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Dissertations / Theses on the topic 'Selective enrichment'

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1

Paranjape, Mrudula. "Hydrogen enrichment by selective surface flow, SSF, membranes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq20879.pdf.

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2

Fang, Xueping. "Targeting biomarkers via CITP-based selective proteome enrichment." College Park, Md. : University of Maryland, 2008. http://hdl.handle.net/1903/8518.

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Thesis (Ph. D.)--University of Maryland, College Park, 2008.<br>Thesis research directed by: Dept. of Chemistry and Biochemistry. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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3

Kahatapitiya, Prathibha Chathurani. "Enrichment of skeletal muscle stem cell transplantation using chemotherapeutic drugs." Thesis, The University of Sydney, 2009. http://hdl.handle.net/2123/4050.

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The BCNU + O6benzylguanine (O6BG) driven selective enrichment strategy was first established for enhanced transplantation of hematopoietic stem cells. This study describes a novel application of this BCNU + O6BG driven selective enrichment strategy in skeletal muscle stem cell transplantation. Furthermore, this study addresses the three main limitations observed in previously reported skeletal muscle stem cell transplantation strategies. Limitation of ineffective donor cells which lack the ability for successful engraftment was overcome by using a heterogeneous population of donor cells which
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Kahatapitiya, Prathibha Chathurani. "Enrichment of skeletal muscle stem cell transplantation using chemotherapeutic drugs." University of Sydney, 2009. http://hdl.handle.net/2123/4050.

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Doctor of Philosophy (PhD)<br>The BCNU + O6benzylguanine (O6BG) driven selective enrichment strategy was first established for enhanced transplantation of hematopoietic stem cells. This study describes a novel application of this BCNU + O6BG driven selective enrichment strategy in skeletal muscle stem cell transplantation. Furthermore, this study addresses the three main limitations observed in previously reported skeletal muscle stem cell transplantation strategies. Limitation of ineffective donor cells which lack the ability for successful engraftment was overcome by using a heterogeneous po
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5

Duffy, Claire Jennifer. "Protein foaming : an investigation of protein enrichment, selective separation and consequences for protein activity." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272352.

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6

Ouyang, Wei Ph D. Massachusetts Institute of Technology. "Hierarchical selective electrokinetic concentration : the universal next-generation biomolecule enrichment technique for molecular diagnostics." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/128323.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2020<br>Cataloged from PDF of thesis.<br>Includes bibliographical references (pages 182-200).<br>Rapid and reliable detection of ultralow-abundance nucleic acids and proteins in complex biological media may greatly advance clinical diagnostics and biotechnology development. Because of the slow mass transport and weak binding kinetics at ultralow concentration of target biomolecules, enrichment of target biomolecules plays an essential role in the detection of ultralow-abundance bio
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7

Clapp, Justin Peter. "Selective enrichment of genomic DNA data for the isolation of species-specific probes in insects." Thesis, University of Hertfordshire, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296538.

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8

Inada, Tomoya. "Evaluation of the sustainability of a logging system consisting of selective logging and line planting in Indonesia." Kyoto University, 2015. http://hdl.handle.net/2433/199361.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第19037号<br>農博第2115号<br>新制||農||1031(附属図書館)<br>学位論文||H27||N4919(農学部図書室)<br>31988<br>京都大学大学院農学研究科森林科学専攻<br>(主査)教授 神﨑 護, 教授 北島 薫, 教授 北山 兼弘<br>学位規則第4条第1項該当
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Hanke, Sabrina Annette [Verfasser], and Christoph [Akademischer Betreuer] Rösli. "Development of Novel Reagents for the Selective Enrichment of Vascular Accessible Proteins and the Identification of Disease-Specific Biomarkers / Sabrina Annette Hanke ; Betreuer: Christoph Rösli." Heidelberg : Universitätsbibliothek Heidelberg, 2015. http://d-nb.info/1180614119/34.

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10

Nyarko, Esmond Boafo. "Improved Recovery And Rapid Identification Of Strains, Mixed Strains, Mixed Species, And Various Physiological States Of Foodborne Pathogens Using Infrared Spectroscopy." ScholarWorks @ UVM, 2014. http://scholarworks.uvm.edu/graddis/276.

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Challenges encountered in pathogen identification and detection include the genetic heterogeneity of strains within species of some foodborne pathogens, isolation of injured cells, mixed strains or mixed species contamination of foods, and differentiation between viable and dead cells. The first objective of this research was to evaluate an isolation medium that was based on time-delayed release (5 to 6 h) of selective agents in tablet format to a modified Listeria recovery enrichment broth (mLRB) medium for enhanced and rapid recovery of injured Listeria. The second objective involved the use
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11

Cartwright, John Alexander. "Study of the leaching of polymetallic sulphide ores using ion selective membranes." Thesis, Queensland University of Technology, 1998.

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12

Agunso, Camila Noia. "Enriquecimento seletivo para pesquisa de Mycobacterium bovis em leite e queijo." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-22042014-162454/.

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O Mycobacterium bovis causa a tuberculose bovina, doença zoonótica que propaga, provavelmente com baixa prevalência, em todo o território nacional e pode ser transmitida pelo leite. A adoção sistemática da pasteurização do leite contribuiu para a redução dos casos humanos da doença, mas em alguns países, como o Brasil, é comum o consumo de leite cru e de seus derivados, o que pode contribuir para ocorrência de casos humanos. A participação desse agente nos atuais índices de tuberculose humana, cujo principal agente é o M. tuberculosis, é pouco investigada, mas acredita-se que seja maior do que
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13

Nilsson, Angelica. "Optimisation of a method for isolation of Clostridium difficile from faeces." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-126892.

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Clostridium difficile is a pathogen for both humans and animals and is often associated with antibiotic-associated diarrhea. Recently, several human cases of C. difficile-infection with increased mortality and morbidity have been reported. In studies performed in different countries C. difficile has been found in meat. Therefore the question whether C. difficile can be a zoonotic agent has been raised. The aim of this study was to optimize a method for isolation of C. difficile from faeces. When C. difficile is isolated from animals that do not have diarrhea the sample must be cultivated in an
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Chen, Xiaohui. "Comparisons of statistical modeling for constructing gene regulatory networks." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/4068.

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Genetic regulatory networks are of great importance in terms of scientific interests and practical medical importance. Since a number of high-throughput measurement devices are available, such as microarrays and sequencing techniques, regulatory networks have been intensively studied over the last decade. Based on these high-throughput data sets, statistical interpretations of these billions of bits are crucial for biologist to extract meaningful results. In this thesis, we compare a variety of existing regression models and apply them to construct regulatory networks which span trancription f
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Lin, Yuan. "In Vivo Imaging of Engraftment and Enrichment of Lentiviral Transduced Hematopoietic Bone Marrow Cells Under MGMT-P140K Mediated Selection." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1295039430.

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Panji, Sumir. "Identification of bacterial pathogenic gene classes subject to diversifying selection." Thesis, University of the Western Cape, 2009. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_5842_1297942831.

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<p>Availability of genome sequences for numerous bacterial species comprising of different bacterial strains allows elucidation of species and strain specific adaptations that facilitate their survival in widely fluctuating micro-environments and enhance their pathogenic potential. Different bacterial species use different strategies in their pathogenesis and the pathogenic potential of a bacterial species is dependent on its genomic complement of virulence factors. A bacterial virulence factor, within the context of this study, is defined as any endogenous protein product encoded by a gene th
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Duval, Johanna. "Eco-valorisation de la plante Kniphofia uvaria : de la plante à la galénique." Thesis, Orléans, 2016. http://www.theses.fr/2016ORLE2045/document.

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À l’heure où l’intégration des enjeux environnementaux dans le développement de procédés éco-efficients joue un rôle essentiel dans le moteur de l’innovation responsable, la chimie verte est devenue l’un des sujets de préoccupation majeure. Ainsi, le développement de nouveaux procédés éco-respectueux pour la production d’ingrédients naturels issus de matières premières végétales renouvelables est devenu une démarche incontournable dans le modèle de recherche. L’objectif de cette thèse a consisté au développement d’une stratégie d’éco-valorisation innovante employant les fluides sub/supercritiq
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18

Telford, Marco 1984. "Genetic diversity and geographic patterns of human herpesvirus 4 and 6." Doctoral thesis, Universitat Pompeu Fabra, 2017. http://hdl.handle.net/10803/664509.

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This thesis focuses on Human herpesvirus 4 and 6, two ubiquitous viruses with a long list of putative disease associations, ranging from malignancies such as lymphomas and carcinomas to multiple sclerosis. To date, the relatively limited genetic data on these organisms hinders the understanding of their variability and their genetic structure at a population level. We here explore wet lab techniques for the production of genetic data in a cost-effective manner in order to reach the order of magnitude that is required to unravel the genetics these viruses. After successfully identifying indiv
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Deehan, Gerald A. JR. "The effect of differential rearing conditions on the consumption of and operant responding for ethanol in the Indiana university selectively bred alcohol-preferring (p) and -non-preferring (np) rat lines." Diss., Manhattan, Kan. : Kansas State University, 2009. http://hdl.handle.net/2097/1390.

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20

Zeng, Yi-You, and 曾乙祐. "Mesoporous TiO2 Nanowires for Selective and Reproducible Enrichment of Phosphopeptides." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/28519707295374520955.

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碩士<br>國立暨南國際大學<br>應用化學系<br>100<br>Abstract Titanium dioxide (TiO2) affinity enrichment has been widely used in phosphoproteomic studies. Although many attempts have been made to fabricate TiO2-based materials for selective enrichment of phosphopeptides, the effects of structural properties, such as crytsallinity, pore diameter, porosity, and specific surface area of TiO2, on selectivity has not been widely explored. Herein, we synthesized TiO2 nanowires with well-defined nanopores and high specific surface area for selective and reproducible enrichment of phosphopeptides from complex peptide m
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Lu, Jing-Wun, and 盧敬文. "Facile Synthesis of Titanium Sulfonate-Functionalized Nanodiamonds for Selective Enrichment of Phosphopeptides." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/3889xh.

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博士<br>國立暨南國際大學<br>應用化學系<br>105<br>In this work, we have developed a novel synthesis route for the production of titanium (IV) sulfonate-functionalized nanodiamonds (Ti4+-SND) as Ti4+-IMAC (Immobilized metal-ion affinity chromatography)adsorbents for selective enrichment of phosphopeptides. Nanodiamonds were first functionalized with polyarginine via EDC-mediated coupling reaction and then the titanium-sulfonate functionalization was performed by mixing with polystyrene sulfate and TiCl4 solutions. The obtained Ti4+-SNDs were used to specific capture of phosphopeptides from standard protein dig
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"Selective Enrichment Of Burkholderia Pseudomallei Outer Membrane Vesicles For Vaccination Against Melioidosis." 2016.

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Burkholderia pseudomallei (Bp) is the causative agent of melioidosis, a disease with a mortality rate of over 40%, and is a major public health concern in the endemic regions of Thailand and northern Australia. Bp is a resilient pathogen capable of surviving in diverse environments including soil, fresh and seawater, and plant and animal tissues for extended lengths of time. Bp is intrinsically resistant to antibiotics, which contributes to persistence and relapse in over 25% of melioidosis patients, and there is currently no vaccine. Our lab has previously shown that immunization with Bp oute
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Chen, Chun-Hua, and 陳俊樺. "Selective Profiling of Protein Cysteine Oxidative Modifications by TiO2 Enrichment and Mass spectrometry." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/37663862666571767886.

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碩士<br>國立暨南國際大學<br>應用化學系<br>100<br>Reversible oxidative cysteine modifications play a critical role in the redox-based signaling mechanism. Dynamic profiling oxidation state of the cysteine residues in protein such as Peroxiredoxin (Prx) presents a formidable challenge. Here, we present a novel approach to selectively isolate sulfopeptides (peptides containing cysteine sulfonic acid and sulfinic acid) from complex digests using TiO2-coated nanodiamonds (TiO2-coated NDs) prior to MS analysis. The method was applied to selectively concentrate sulfopeptides from either a highly dilute solution or
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Hung, Shain-Un, and 洪翔文. "Selective Enrichment of Phosphopeptides from HeLa cell lysate using Titanium Dioxide-coated Nanodiamonds." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/86913670871509553250.

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碩士<br>國立暨南國際大學<br>應用化學系<br>101<br>Selective isolation and concentration of phosphopeptides is a prerequisite step prior to MS analysis. Currently titanium oxide affinity chromatography has gained more and more popularity among the common phosphopeptide isolation methods. Here, we present a new hybrid material, TiO2-coated nanodiamonds (TiO2-NDs), for selective enrichment of phosphopeptides from complex peptide mixtures. The results showed that TiO2-NDs outperformed the commercial TiO2 beads for higher enrichment capacity and specificity toward phosphopeptides. We identified 932 unique phos
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Tsai, Peng-Hsuan, and 蔡朋璇. "Facile Preparation of Chitosan-Immobilized Magnetic Nanoparticles for Selective Enrichment of Phosphorylated Peptides." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/34181588009116319015.

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碩士<br>國立暨南國際大學<br>應用化學系<br>102<br>A facile and effective approach to synthesize chitosan-immobilized magnetic nanoparticles was proposed using carbon-encapsulated iron nanoparticles (Fe@CNPs) as the magnetic core.Poly(acrylic acid)-coated Fe@CNPs were prepared by free radical polymerization of acrylic acid and used as magnetic substrates for subsequent Chitosan immobilization.The chitosan-immobilized magnetic probes were applied for rapid and selective identification of phosphopeptides from complex peptide mixtures by MALDI-TOF MS.
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Lai, Mei Chu, and 賴美珠. "Evaluation of sensitivity and specificityin combination of selective media and enrichment broth for Salmonella isolation from human stoolsEvaluation of sensitivity and specificityin combination of selective media and enrichment broth for Salmonella iso." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/71281041756709802713.

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碩士<br>大葉大學<br>生物產業科技學系碩士在職專班<br>93<br>Salmonellae is one of the most common causes of human gastroenteritis. This study compared the performance of three selective media namely CAS (CHROMagar Salmonella medium), HE (Hektoen enteric agar) and XLD (Xylose lysine desoxycholate agar) and three enrichment broths namely GN (Gram-negative broth), SB (Selenite broth) and SBG (Selenite brilliant green sulfa enrichment broth) to optimize the use of plating media and enrichment broths for isolation of Salmonella spp. from human stools. The 304 stools were cultured onto the above three selective media by
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Lin, Tzu-Hsiang, and 林子翔. "Selective enrichment of catecholamines using iron oxide nanoparticles followed by CE with UV detection." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/46065879865126615300.

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碩士<br>國立中山大學<br>化學系研究所<br>100<br>This study examines the use of unmodified magnetite nanoparticles (Fe3O4 NPs) for selective extraction and enrichment of the catecholamines dopamine (DA), noradrenaline (NE), and adrenaline (E), prior to analysis using capillary electrophoresis with UV detection. Coordination between Fe3+ on-the-surface Fe3O4 NPs and the catechol moiety of catecholamines enables Fe3O4 NPs to capture catecholamines from an aqueous solution. We obtained maximum loading of catecholamines on the NP surface by adjusting the pH of the solution to 7.0. In addition, catecholamine loadi
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28

Chang, Chia-Kai, and 張家愷. "Selective enrichment of phosphoproteins/ multiphosphorylated peptides using polyarginine coated diamond nanoaprticles as high affinity probes." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/28994682663254151671.

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碩士<br>國立暨南國際大學<br>應用化學系<br>96<br>Mass spectrometric identification of phosphoproteins and their phosphorylation sites is challenging , due to their low abundance in nature. Therefore, it is essential to perform an enrichment strategy prior to MS analysis. In this work, we employed polyarginine (PA) - coated diamond nanoparticles (nominal size 100 nm) as high affinity probes to selectivity capture phosphoproteins / phosphopeptides from a complex solution of tryptic digested proteins. Compared to IMAC and MOAC methods for phosphopeptide enrichment, The polyarginine-coated nanodiamonds show an
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"Microbial Electrochemical Cells for Selective Enrichment and Characterization of Photosynthetic and Haloalkaliphilic Anode-Respiring Bacteria." Doctoral diss., 2013. http://hdl.handle.net/2286/R.I.18043.

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abstract: Microbial electrochemical cells (MXCs) are promising platforms for bioenergy production from renewable resources. In these systems, specialized anode-respiring bacteria (ARB) deliver electrons from oxidation of organic substrates to the anode of an MXC. While much progress has been made in understanding the microbiology, physiology, and electrochemistry of well-studied model ARB such as Geobacter and Shewanella, tremendous potential exists for MXCs as microbiological platforms for exploring novel ARB. This dissertation introduces approaches for selective enrichment and characterizati
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Chan, Andrew. "A Method for Selective Concentrating of DNA Targets by Capillary Affinity Gel Electrophoresis." Thesis, 2013. http://hdl.handle.net/1807/35786.

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A method for the selective concentrating of DNA targets using capillary affinity gel electrophoresis is presented. Complementary ssDNA targets are retained through hybridization with oligonucleotide probes immobilized within polyacrylamide gels while non-complementary targets are removed. The captured DNA targets were concentrated by step elution, where a localized thermal zone was applied in small steps along the capillary. Evaluation of the selective capture of a 150 nt DNA target in a complicated mixture was carried out by factorial analysis. Gels with a smaller average pore size were found
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HSIAO, CHEN-FANG, and 蕭争芳. "Preparation of TiO2 Hollow Nanocages for Highly Selective Enrichment of Phosphopeptides by Nanodiamond-based Template Method." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/b3q3f8.

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碩士<br>國立暨南國際大學<br>應用化學系<br>106<br>In this work, we have developed a novel synthesis strategy for the production of TiO2 hollow nanocage for highly efficient enrichment of phosphopeptides via a Nanodiamond(ND)-assisted template method. We reduced the ND surface to OH groups and then coated the silica dioxide and titanium dioxide on the ND by sol-gel method, and the ND template was removed by calcination at 650 degrees for eight hours. The nanostructure of the obtained TiO2 hollow nanocage was characterized by nitrogen adsorption-desorption isotherms, X-ray powder diffraction (XRD), transmission
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Hsieh, Feng-Jen, and 謝豐任. "Selective Enrichment of Multiply Phosphorylated Peptides Using Polyarginine-coated Nanodiamonds Prior to Liquid Chromatography Mass Spectrometric Analysis." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/08610896987120268256.

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碩士<br>國立臺灣大學<br>化學研究所<br>98<br>Identification of multi-phosphorylated peptides by liquid chromatography-tandem mass spectrometry(LC-MS/MS)remains a challenging task due to the poor ionization of the species. For this reason, various kits to selectively enrich phosphopeptides prior to MS analysis have been developed and commercialized, but most of them are selective only for singly phosphorylated peptides. Interestingly, poly-arginine-coated nanodiamond(PA-ND)shows a high selectivity for multi-phosphorylated peptides and this has been demonstrated by Chang et al. For further applications in
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Shiau, Kai Jung, and 蕭凱鐘. "A Novel Two–Step Enrichment Procedure for Fractionation and Selective Identification of Multiply and Singly Phosphorylated Peptides." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/24101832783251335952.

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碩士<br>國立暨南國際大學<br>應用化學系<br>97<br>Abstract Despite recent technical advances, comprehensive characterization of protein phosphorylation remains a challenge. We explored the possibility using a two–step enrichment procedure for fractionation and selective identification of multiply and singly phosphorylated segments from enzymatic digestion of complex proteins. The procedure involved isolation of multiply phosphorylated peptides from solution using polyarginine-coated nonadiamond and subsequent isolation of singly phosphorylated peptides from the same pool of solution using TiO2-coated magnetic
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Wilson, TK. "Development of a streamlined, selective-enrichment culture, one-tube (RT-)PCR-enzyme hybridization assay to detect bacterial fish pathogens in covertly infected farmed salmonids." Thesis, 2003. https://eprints.utas.edu.au/22118/1/whole_WilsonTeresaKaye2003_thesis.pdf.

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A new system which offers a low-cost and high performance means for detecting four bacterial pathogens Aeromonas salmonicida, Tenacibaculum maritimum, Lactococcus garvieae and Yersinia ruckeri in covertly infected farmed salmonid fish has been developed. The system couples Selective Enrichment Culture (SEC), Polymerase Chain Reaction (PCR) and Enzyme Hybridization Assay (EHA) technologies to provide streamlined high-throughput sample processing suitable for large scale surveillance and monitoring programs. The SEC media used for the technology were those developed by T.Wilson and J.Ca
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Motaragheb, Jafarpour Saeed. "Investigation of multicomponent catalyst systems for type-selective growth of SWCNTs by CVD." 2019. https://monarch.qucosa.de/id/qucosa%3A38384.

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Excellent electronic properties of semiconducting single-walled carbon nanotubes (sc-SWCNTs) motivated the investigation for using them in different application areas such as microelectronics, sensorics, MEMS and MOEMS. However, challenges arise from the lack of selectivity with respect to electronic type and chirality as well as ensuring high quality, high purity and well-aligned SWCNTs during fabrication process. Catalytic chemical vapour deposition (CCVD) has shown great potential in direct synthesis of high quality SWCNTs with chiral or type selectivity. This thesis addresses three importa
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Ward, Rachel Jane. "The use of denaturing gradient gel electrophoresis in examining the species-specific influence of ectomycorrhizal fungi on selective bacteria enrichment in the mycorrhizosphere of Pinius rigida grown in a natural pine barrens habitat." 2007. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.16793.

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TUEN, LAM TUNG, та 林東團. "ENRICHMENT OF STEM CELL DERIVED NEURON BY βIII-TUBULIN TARGETED LINEAGE SELECTION". Thesis, 2007. http://ndltd.ncl.edu.tw/handle/79025839454287588854.

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碩士<br>長庚大學<br>醫學生物技術研究所<br>95<br>ABSTRACT ENRICHMENT OF STEM CELL DERIVED NEURON BY βIII-TUBULIN TARGETED LINEAGE SELECTION Neural stem cells are the prime candidate for studying the neuro-genesis and as a donor sources for the cell replacement therapy in several neurological diseases. Study indicated that neural stem cell has the potential to proliferate in vitro and differentiate into neuronal-like cells with biochemical and electro-physiological properties. Although the neural stem cell provided an unlimited source of neuron, the current differentiation protocol could be difficult to achie
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Kim, Jinho. "A Microfluidic Approach to Selection and Enrichment of Aptamers for Biomolecules and Cells." Thesis, 2013. https://doi.org/10.7916/D8HX1M18.

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This thesis presents microfluidic devices for selection and amplification of nucleic acids (aptamers) that bind to specific targets. Aptamers are very attractive molecules in many biological applications due to their interesting properties including high target binding affinities and stability. Using conventional platforms for aptamer generation (SELEX, systematic evolution of ligands by exponential enrichment) is labor-intensive and time consuming. Microfluidic devices have been developed to improve the aptamer enrichment efficiency. However, aptamer generation using these devices is still in
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HUANG, CHIEN-YU, and 黃千瑜. "Selection enrichment and detection of phosphopeptides using zirconium ion and polyarginine functionalized nanodiamonds." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/92641123990999522148.

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碩士<br>國立暨南國際大學<br>應用化學系<br>104<br>In this work, we have developed a facile method for efficient production of metal-ion and polyarginine co-functionalized nanodiamonds (denotes as PA-ND@PSS-Mn+) as a novel IMAC platform for phosphoproteomic analysis. Polyarginine-coated nanodiamonds (PA-ND) were mixed with poly-styrenesulfonate(PSS) via multivalent electrostatic interactions. Immobilization of zirconium ion on the surface of poly-arginine/poly-styrenesulfonate(PSS) functionalized nanodiamonds was done by a 30-min incubation in ZrCl4 solution at room temperature. The PA-ND@PSS-Zr4+ was furth
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Chuang, Chun Chieh, and 莊竣傑. "Selection and Enrichment of Liver Cancer Stem Cells by Using Hyaluronan Based Polyelectrolyte Multilayer Films." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/08143864810222263614.

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