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Dissertations / Theses on the topic 'Selenic acid'

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Published: 4 June 2021
Last updated: 26 July 2025

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1

張仁傑 and Yan-kit Cheung. "Synthesis and properties of selena and other selenium-containing long chain fatty acid derivatives." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1992. http://hub.hku.hk/bib/B3123303X.

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2

Cheung, Yan-kit. "Synthesis and properties of selena and other selenium-containing long chain fatty acid derivatives /." [Hong Kong : University of Hong Kong], 1992. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13288581.

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3

Silva, Vinícius Martins. "Characterization of genotype variation and agronomic biofortification of cowpea with selenium : impacts on phytic acid and nutritional quality of grains /." Ilha Solteira, 2019. http://hdl.handle.net/11449/180710.

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Orientador: André Rodrigues dos Reis<br>Resumo: O selênio (Se) é um nutriente para humanos e animais e um elemento benéfico para as plantas, sua baixa concentração nos solos do Brasil pode gerar deficiência nos animais e humanos. O fitato é a principal forma de reserva de fósforo (P) encontrado nas sementes de plantas, sendo considerado um “anti-nutriente” por formar complexos não digeríveis com nutrientes como Fe, Ca e Zn. Desta forma, existe a necessidade de se buscar alternativas para aumentar os teores de Se e reduzir o teor de fitato nas partes comestíveis de cultivares modernos. O objeti
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4

Presseau, Nathalie. "Synthesis and Study of a Persistent Selenenic Acid and Preliminary Studies of Thiol Oxidation." Thèse, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/30718.

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Selenenic acids and other organoselenium compounds are important both in organic and biochemistry. In organic chemistry, syn-elemination of selenoxides is used to prepare alkenes, giving a selenenic acid by-product. In biochemistry, selenocysteine is catalytically active in a variety of selenoenzymes, which have antioxidant properties, and is oxidized to a selenenic acid intermediate. For example, glutathione peroxidase (GPx) plays a role in fighting oxidative damage by catalyzing the reduction of hydroperoxides. Previous studies have shown that the lighter chalcogen analogue of selenenic acid
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5

Huang, Donglin. "Heterogeneous reduction of selenite by zero valent iron-steel wool." Morgantown, W. Va. : [West Virginia University Libraries], 2010. http://hdl.handle.net/10450/11233.

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Thesis (Ph. D.)--West Virginia University, 2010.<br>Title from document title page. Document formatted into pages; contains ix, 106 p. : ill. (some col.). Includes abstract. Includes bibliographical references.
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6

Wan, Lili. "Determination of total selenium and seleno-amino acids in yeast and aquatic organisms by liquid chromatography and inductively coupled plasma mass spectrometry." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/4683.

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Thesis (Ph. D.)--University of Missouri-Columbia, 2007.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on March 4, 2008) Vita. Includes bibliographical references.
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7

Baldissarri, Mattia. "Studio di un impasto acido funzionale ad elevata biodisponibilita di selenio." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amslaurea.unibo.it/6185/.

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Dal 2008, sono evidenti che i benefici del selenio nell'organismo dipendono dalla forma in cui è ingerito, stabilendo che quella organica è migliore dell'inorganica. L’introduzione di selenio raccomandato a livello internazionale è di 55-70 μg/giorno e la sua specie chimica efficace dal punto di vista biologico è la seleniometionina. Infatti, si può affermare che il selenio in forma inorganica possieda una bassa bioattività rispetto al selenio legato agli aminoacidi (Se-metionina e Se-cisteina) di maggiore bioattività. Nell’ambito dei prodotti lievitati da forno, uno dei fattori che desta mag
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8

Reyes, Leila. "Involvement of inflammatory oxidants in cardiac ischaemia/reperfusion injury." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/19667.

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Oxidative stress is a major feature of cardiac ischaemia/reperfusion (I/R) injury, with strong evidence implicating infiltrating leukocytes, in particular neutrophils, as a major source of oxidants in the infarcted myocardium. Activated leukocytes release the peroxidase enzyme, myeloperoxidase (MPO), which can produce the oxidants hypochlorous acid (HOCl) and hypothiocyanous acid (HOSCN). Chapter 3 examines the differential cellular effect of (patho)-physiological levels of HOCl and HOCN in cardiomyocytes. Both HOCl and HOSCN induced cellular damage characteristic of cardiac I/R injury and hig
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9

Zhang, Wen. "Structure and Function Studies of Selenium Substituted Nucleic Acids." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/chemistry_diss/63.

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Nucleic acids are responsible for the storage of genetic information and directly participate in gene replication, transcription and expression, and thereby the control of nucleic acids leads to the regulation of genetic information flow and gene expression. Meanwhile, many non-coding RNAs are in-volved in signal transduction directly. Moreover, nucleic acid-based therapeutic strategies have been lead to drug candidates and are effective tools in drug discovery and disease study at the molecular level as well as the genetic level. Consequently, the 3D crystal structure study and related functi
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10

Lin, Lina. "Synthesis, Structure, Function and Biomedical Studies of Nucleic Acid Derivatized with Selenium." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/biology_diss/77.

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Nucleic acids are macromolecules in cells for storing and transferring genetic information. Moreover, nucleic acids, especially RNAs, can fold into well-defined 3D structures and catalyze biochemical reactions. As ubiquitous biological molecules in all living systems, nucleic acids are important drug targets, and they can also be used in diagnostics and therapeutics. Structural information of nucleic acids provides the foundation for DNA and RNA function studies. X-ray crystallography has been a useful tool for structural studies of bio-macromolecules at atomic level. There are two major probl
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11

Wennberg, Maria. "Biomarkers of fish consumption and risk of stroke or myocardial infarction." Doctoral thesis, Umeå : Umeå university, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33906.

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12

Robey, Stephanie. "Reactions of Platinum(II) Compounds with Selenium Containing Amino Acids." TopSCHOLAR®, 2013. http://digitalcommons.wku.edu/theses/1252.

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Platinum(II) anticancer medications essentially react with DNA forming kinks inthe double helix of DNA and causing apoptosis. It has also been noted that theseanticancer medications react with methionine and cysteine in the body. With the new discoveries of selenium containing amino acids including selenomethionine and selenocysteine, new research is ongoing to see what types of products can be formed from these amino acids. Our research reacts [Pt(Met-S,N)Cl2] 2+ with selenomethionine to determine what types of products are produced. Monochelates including [Pt(SeMet-Se,N)Cl2] 2+ have formed t
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13

rob, abdur. "Protein-Nucleic Acid Interactions in Nuclease and Polymerases." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/chemistry_diss/54.

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DNA polymerase binds to the double stranded DNA and extends the primer strand by adding deoxyribonucletide to the 3’-end. Several reactions in the polymerase active site have been reported by Kornberg in addition to the polymerization. We observed DNA polymerase I can act as a pyrophosphatase and hydrolyze deoxyribonucletide. In performing the pyrophosphatase activity, DNA polymerase I requires to interact with RNA. RNA in general, was found to activate the DNA polymerase I as pyrophosphatase. This hydrolysis causes depletion of dNTP and inhibits DNA polymeration synthesis in vitro. In this RN
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14

Rode, Katharina. "Studies Toward Selenium-pi-Acid Catalyzed Oxidative Functionalizations of Olefinic and Acetylenic Multiple Bonds." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://hdl.handle.net/21.11130/00-1735-0000-0005-1491-0.

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15

Mokmeli, Mohammad. "Kinetics of selenium and tellurium removal with cuprous ion from copper sulfate-sulfuric acid solution." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/46407.

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Dissemination of selenium and tellurium in pyritic ores and many of the sulphide minerals results in the contamination of pregnant leach solutions and electrolytes in hydrometallurgical treatment of sulphide ores and residues. In an effort to reduce the detrimental effects of selenium and tellurium, it has been of great interest to remove selenium and tellurium from contaminated solutions to lower levels than allowed in regulations, product specifications or process requirements. The selenium and tellurium content of the solution may be reduced into insoluble precipitates of copper selenides a
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16

Mdluli, Siyabonga Beizel. "Photoluminescent Responses of Polypropylenethiophenoimine-Co-Pedot/ Polystyrenesulfonic Acid and Zinc Selenide Quantum Dot Composite Materials." University of the Western Cape, 2018. http://hdl.handle.net/11394/6320.

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Magister Scientiae - MSc (Chemistry)<br>Research in renewable energy has gained momentum and become a centre of attention as a possible alternative solution to the energy catastrophe. This is attained by the use of solar energy as an alternative clean energy source. The creation of solar energy arises as a consequence of direct conversion of light photons from the sun into electrical energy by the use of solar cells made up of semiconducting materials incorporated into the system. In the context of solar energy, hybrid photovoltaics comprising of organic molecules and nanomaterials have emerge
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17

Nxusani, Ezo. "Novel 3-mercaptopropionic acid capped iridium selenide quantum dots modified electrochemical immunosensor for the detection of fish toxin, nodularin." Thesis, University of the Western Cape, 2012. http://hdl.handle.net/11394/4616.

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>Magister Scientiae - MSc<br>A novel 3-mercaptopropionic acid capped iridium selenide quantum dots based label free impedimetric immunosensor was successfully constructed. The 3-mercaptopropionic acid capped iridium selenide quantum dots synthesized were studied using HRTEM, revealing the formation of very small sizes, of about 3 nm. The optical Uv-Vis absorption wavelength of the quantum dots is blue-shifted, a phenomenon explained by the effective mass approximation (EMA) for semiconducting materials with sizes below 10 nm. Using cyclic voltammetry it is noted that the quantum dots have inte
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18

Alonis, Melenie Lee. "Selenotrisulfide Derivative of Alpha-Lipoic acid: Evaluation in a Cell Culture Model for Potential Use as a Topical Antioxidant." Master's thesis, University of Central Florida, 2005. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3451.

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Selenium is a required micronutrient in mammalian cells. It is incorporated in the form of selenocysteine into selenoenzymes such as glutathione peroxidase and thioredoxin reductase, and is absolutely required for activity. Thioredoxin reductase is necessary for reduction of oxidized thioredoxin and therefore plays a major role in maintaining the redox status of the cell. Glutathione peroxidase is responsible for reducing peroxides into their corresponding alcohols and water. Together, these selenoenzymes constitute a significant part of the cell's arsenal to defend itself against oxidative st
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19

Rode, Katharina [Verfasser]. "Studies Toward Selenium-pi-Acid Catalyzed Oxidative Functionalizations of Olefinic and Acetylenic Multiple Bonds / Katharina Rode." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://d-nb.info/1218299258/34.

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20

Sheng, Jia. "Synthesis, Structure and Function Studies of Selenium and Tellurium Derivatized Nucleic Acids." Digital Archive @ GSU, 2009. http://digitalarchive.gsu.edu/chemistry_diss/30.

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Nucleic acids play important roles in living systems by storing and transferring genetic information and directing protein synthesis. Recently, it was found that nucleic acids can catalyze chemical and biochemical reactions similar to protein enzymes. In addition, they can also serve as drug targets for the treatment of deadly diseases such as AIDS and cancers. As a result, the 3D structure study of nucleic acids and proteinnucleic acids complexes by X-ray crystallography has become one of the most active research areas. However, the two intrinsic bottlenecks of macromolecule X-ray crystallogr
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21

Caton-Williams, Julianne Marie. "Synthesis and Enzymatic Studies of Selenium Derivatized Nucleosides, Nucleotides and Nucleic Acids." Digital Archive @ GSU, 2009. http://digitalarchive.gsu.edu/chemistry_diss/42.

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Nucleoside 5-triphosphates are the building blocks to synthesis of nucleic acids. Nucleic acids (RNA and DNA) participate in many important biological functions in living systems, including genetic information storage, gene expression, and catalysis. Nucleoside 5- triphosphates have many important therapeutic and diagnostic applications. To understand how these triphosphates are utilized in living systems, numerous synthetic mimics have been prepared and used as active metabolites of certain drugs and molecular probes. Over the years, nucleic acids have been modified at the nucleobase, sugar m
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22

Lafin, John Thomas. "Methylseleninic acid induces lipid peroxidation and sensitizes head and neck cancer cells to radiation therapy." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5543.

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Combination radiation and chemotherapy are commonly used to treat locoregionally advanced head and neck squamous cell carcinoma. Aggressive dosing of these therapies is significantly hampered by side effects due to normal tissue toxicity. Selenium represents an adjuvant that selectively sensitizes cancer cells to therapy, potentially by inducing lipid peroxidation (LPO). This study investigated whether one such selenium compound, methylseleninic acid (MSA), induces LPO and radiation sensitivity in HNSCC cells. Results from BODIPY C11 oxidation and ferric thiocyanate assay revealed that MSA ind
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23

Cardozo, Leila. "Perfil de ácidos graxos, estabilidade oxidativa e aspectos sensoriais do leite de vacas suplementadas com óleo de linhaça na dieta e selenito de sódio injetável." Universidade Federal de Santa Maria, 2011. http://repositorio.ufsm.br/handle/1/10085.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The objective of the present work was to evaluate the effect of dietary linseed oil with or without injection of sodium selenite upon fatty acid profile and oxidative stability of milk from dairy cows as well as the acceptance of the milk and the increasing order of preference by the evaluators. Chapter 1 describes the experiment where fourteen cows were allocated into four treatments: Group 1 which received daily 400 mL of linseed oil (LIN); Group 2, 400 mL of linseed oil + 0.2 mg/BW sodium selenite IM (LINSe); Group 3, untreated
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24

Ling, Jie Albrecht-Schmitt Thomas E. "Hydrothermal syntheses, structures, and properties of new iodate and selenite compounds of transition metals, lanthanides, and actinides." Auburn, Ala, 2007. http://repo.lib.auburn.edu/2007%20Fall%20Dissertations/LING_JIE_49.pdf.

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25

Rashid, Mohammad Mamunur. "The Investigation of Photocatalytic and Adsorptive Properties of Humic Acid Grafted Magnetite Nanoparticles for the Remediation of Arsenic, Selenium and Phosphorous from Water." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3745.

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The crisis of freshwater has been a big concern worldwide. Water contamination that occurs through the discharge of toxic pollutants from different natural and anthropogenic sources have worsened the situation. Adsorption has emerged as a simple and economical water treatment procedure although the challenge is to find the right adsorbent that can efficiently remove the target contaminant followed by their easy recovery from the reaction vessel. In this dissertation, I have focused on the synthesis, characterizations and applications of environmentally compatible and magnetic humic acid coated
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26

Papp, Laura V., and n/a. "Multiple Levels of Regulation of Human SECIS Binding Protein 2, SBP2." Griffith University. School of Biomolecular and Biomedical Science, 2006. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20070208.145623.

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Selenium is an essential trace mineral of fundamental importance to human health. Its beneficial functions are largely attributed to its presence within a group of proteins named selenoproteins in the form of the amino acid selenocysteine (Sec). Recently, it was revealed that the human selenoproteome consists of 25 selenoproteins, and for many of them their function remains unknown. The most prominent known roles of selenoproteins are to maintain the intracellular redox homeostasis, redox regulation of intracellular signalling and thyroid hormone metabolism. Sec incorporation into selenoprotei
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Papp, Laura V. "Multiple Levels of Regulation of Human SECIS Binding Protein 2, SBP2." Thesis, Griffith University, 2006. http://hdl.handle.net/10072/367554.

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Selenium is an essential trace mineral of fundamental importance to human health. Its beneficial functions are largely attributed to its presence within a group of proteins named selenoproteins in the form of the amino acid selenocysteine (Sec). Recently, it was revealed that the human selenoproteome consists of 25 selenoproteins, and for many of them their function remains unknown. The most prominent known roles of selenoproteins are to maintain the intracellular redox homeostasis, redox regulation of intracellular signalling and thyroid hormone metabolism. Sec incorporation into selenoprotei
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28

Thompson, Richard A. "Conformational Bias in 2'-Selenium-Modified Nucleosides and the Effect on Helical Structure and Extracellular Recombinant Protein Production: Current Systems and Applications." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/chemistry_theses/37.

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Part One. X-ray crystallography has benefited from the synthetic introduction of selenium to different positions within nucleic acids by easing the solving of the phase problem. Interestingly, its addition to the 2' position of the ribose ring also significantly enhances crystal formation. This phenomenon was investigated to describe the effect of selenium-based and other 2' modifications to the ribose ring of nucleosides in solution, as well as the incorporation of the selenium-modified nucleotides into a helical structure. This work correlates the difference in conformation propensity betwe
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29

Pappas, Athanasios C. "Supplementation of broiler breeder diets with selenium and polyunsaturated fatty acids affects the egg, the embryo and the growing chick." Thesis, University of Glasgow, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425263.

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30

Pieniz, Simone. "Avaliação das atividades antimicrobiana, antioxidante e capacidade de bioacumulação de selênio em células de Enterococcus." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/27839.

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As bactérias ácido lácticas (BAL) possuem papel importante em uma ampla variedade de alimentos, incluindo produtos lácteos e cárneos. Neste trabalho foram investigadas as atividades antimicrobiana e antioxidante, do sobrenadante bruto e do extrato intracelular, de 36 BAL isoladas de produtos lácteos e cárneos. Estas bactérias foram identificadas através do seqüenciamento do rRNA da região 16S. A análise através do GenBank BLAST revelou que todos os isolados pertencem ao gênero Enterococcus. Três isolados foram identificados como E. hirae, um isolado como Enterococcus sp., 17 como E. faecium e
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31

Celante, Gizele. "Controle da regiosseletividade de abertura de 2,3-epóxi-éster empregando selenolatos metálicos visando a obtenção de seleno-α-hidroxi-éster." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-21062017-081349/.

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No presente trabalho foram realizados estudos de regiosseletividade das reações de abertura de 2,3-epoxipropanoato de etila (1) utilizando diferentes nucleófilos de selênio e algumas dessas reações foram desenvolvidas com a adição do ácido de Lewis trifluoreto de boro dietil éter (BF3&#183;Et2O). A abertura desse oxirano ao utilizar os nucleófilos MeSeMgCl e MeSeLi-BF3&#183;Et2O ocorreu seletivamente no Carbono C-3 formando o composto de interesse (3-metilseleno 2-hidroxipropanoato de etila), já ao utilizar MeSeLi (em ausência ácido de Lewis) a abertura procedeu-se seletivamente no carbono C-2
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32

Karimi, Farhad. "[11C]Carbon Monoxide in Palladium- / Selenium-Promoted Carbonylation Reactions : Synthesis of 11C-Imides, Hydrazides, Amides, Carboxylic Acids, Carboxylic Esters, Carbothioates, Ketones and Carbamoyl Compounds." Doctoral thesis, Uppsala universitet, Avdelningen för organisk kemi, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2931.

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[11C]Carbon monoxide in low concentrations has been used in palladium- or seleniummediated carbonylation reactions such as the synthesis of 11C-imides, hydrazides, amides, carboxylic acids, esters, carbothioates, ketones and carbamoyl compounds. In these reactions aryl iodides have been used in most cases. However, less reactive aryl triflate, chloride and bromides were activated using tetrabutylammonium iodide. The reactivities of nucleophiles may have influence on the radiochemical yield of the 11Clabelled compounds. Carboxyamination of aryl halides using aniline derivatives yielded 10% of t
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33

SHAH, MONIKA. "CHARACTERIZATION OF BIOLOGICALLY IMPORTANT VOLATILE AND NON-VOLATILE MOLECULES VIA HETEROATOM DETERMINATION USING CHROMATOGRAPHY AND MASS SPECTROMETRY." University of Cincinnati / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1148309632.

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34

Obah, kosso Anne. "Arylsélénation et sélénocyanation d'hétérocycles riches en électrons." Electronic Thesis or Diss., Aix-Marseille, 2019. http://www.theses.fr/2019AIXM0643.

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Ce travail s’inscrit dans la recherche et le développement de nouvelles méthodologies pour la synthèse de molécules portant un groupement sélénocyané ou arylsélanyle. Dans une première partie, le trisélénodicyanure (TSD) généré à partir du malononitrile et du dioxyde de sélénium a été utilisé pour la substitution électrophile d’hétérocycles riches en électrons tels que les imidazohétérocycles, les chromèn-4-ones et également pour l’ipso-sélénocyanation d’acides arylboroniques sans l’utilisation de métaux. Cette sélénocyanation permet d’accéder rapidement et de façon fiable aux dimères diséléni
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35

Sá, Fabiano Cesar [UNESP]. "Energia mecânica, energia térmica e moagem na extrusão de alimentos para cães e gatos." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/126533.

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Made available in DSpace on 2015-08-20T17:10:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-03-20. Added 1 bitstream(s) on 2015-08-20T17:25:55Z : No. of bitstreams: 1 000835580.pdf: 2655261 bytes, checksum: e7af4bb36dc30d671baadb257d339877 (MD5)<br>A eficiência do processo de extrusão está diretamente relacionada à energia total transferida para a massa de ração. Extrusoras de rosca simples usualmente implementam ao redor de 20kWh/ton de energia mecânica específica (EME), mas menos se conhece à respeito da implementação de energia térmica específica (ETE) e das implicações da rela
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Sá, Fabiano Cesar. "Energia mecânica, energia térmica e moagem na extrusão de alimentos para cães e gatos /." Jaboticabal, 2015. http://hdl.handle.net/11449/126533.

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Orientador: Aulus Cavalieri Carciofi<br>Banca: Atushi Sugohara<br>Banca: Dalton José Carneiro<br>Banca: Ricardo Souza Vasconcellos<br>Banca: Luciano Trevisan<br>Resumo: A eficiência do processo de extrusão está diretamente relacionada à energia total transferida para a massa de ração. Extrusoras de rosca simples usualmente implementam ao redor de 20kWh/ton de energia mecânica específica (EME), mas menos se conhece à respeito da implementação de energia térmica específica (ETE) e das implicações da relação entre ETE:EME no processamento de alimentos para cães e gatos. O presente estudo avaliou
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37

DeSilva, Veronica. "Selenium redox cycling isolation and characterization of a stimulatory component from tissue of loblolly pine for multiplication of somatic embryos; development of an assay to measure l-phenylalanine concentration in blood plasma /." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/29788.

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Thesis (Ph.D)--Chemistry and Biochemistry, Georgia Institute of Technology, 2007.<br>Committee Chair: Sheldon May; Committee Members: Nicholas Hud, Stanley Pollock, James Powers, and Gerald Pullman. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Geszke-Moritz, Malgorzata. "Synthesis of stable and non-cadmium containing quantum dots conjugated with folic acid for imaging of cancer cells." Thesis, Vandoeuvre-les-Nancy, INPL, 2011. http://www.theses.fr/2011INPL066N/document.

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Les Quantum Dots (QDs) sont des particules cristallines de semi-conducteur ou du métal de forme sphérique et de dimension nanométrique. L'intérêt majeur des QDs réside dans leur grande adaptabilité à de nombreuses applications biologiques.Le but de mon travail était de développer une nouvelle classe de QDs de faible toxicité afin de les utiliser pour la bio-imagerie des cellules cancéreuses. Pour cela, il est nécessaire de préparer des sondes hydrosolubles, photostables, biocompatibles, de luminescence élevée et possédant une faible toxicité. La synthèse des cœurs de type ZnS and ZnSe dopés au
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Karimi, Farhad. "[11C]Carbon Monoxide in Palladium- / Selenium-Promoted Carbonylation Reactions : Synthesis of 11C-Imides, Hydrazides, Amides, Carboxylic Acids, Carboxylic Esters, Carbothioates, Ketones and Carbamoyl Compounds." Doctoral thesis, Uppsala University, Organic Chemistry, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2931.

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<p>[<sup>11</sup>C]Carbon monoxide in low concentrations has been used in palladium- or seleniummediated carbonylation reactions such as the synthesis of <sup>11</sup>C-imides, hydrazides, amides, carboxylic acids, esters, carbothioates, ketones and carbamoyl compounds.</p><p>In these reactions aryl iodides have been used in most cases. However, less reactive aryl triflate, chloride and bromides were activated using tetrabutylammonium iodide.</p><p>The reactivities of nucleophiles may have influence on the radiochemical yield of the <sup>11</sup>Clabelled compounds. Carboxyamination of aryl ha
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40

Luchese, Cristiane. "Mecanismos envolvidos no efeito antioxidante do disseleneto de difenila no dano oxidativo causado pela exposição à fumaça do cigarro em ratos jovens." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/4411.

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Cigarette smoking is a complex mixture of many constituents identified, among them reactive substances (reactive oxygen and nitrogen species), which are capable of initiating or promoting oxidative damage. Lungs and brain are affected by cigarette smoke exposure. Exposure to cigarette smoke is related to development of diseases in children and adults. However, children are more susceptible than adults to damage caused by cigarette smoke. Thus, the use of antioxidants is a good alternative to protect tissues of oxidative damage caused by cigarette smoke exposure. Diphenyl diselenide [(PhSe)2] i
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Wilhelm, Ethel Antunes. "Ação farmacológica do 3-alquinil selenofeno em modelos de convulsão em ratos jovens." Universidade Federal de Santa Maria, 2012. http://repositorio.ufsm.br/handle/1/4453.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Seizures have important consequences in terms of mortality and quality of life of the affected population, being a risk factor for the development of cognitive and behavioral abnormalities. Considering the promising pharmacological properties of molecules containing selenium, in article 1, we evaluated the anticonvulsant action of 1-(2,5-diphenylselenophen-3-yl)-3-methylpent-1-yn-3-ol, generically called 3-alkynyl selenophene (3-ASP) against seizures induced by pilocarpine (PC), pentylenetetrazole (PTZ) and kainate (KA) in 21-day
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42

Chapple, Charles E. "Finding a needle in haystack: the Eukaryotic selenoproteome." Doctoral thesis, Universitat Pompeu Fabra, 2009. http://hdl.handle.net/10803/7184.

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Les selenoproteïnes constitueixen una família diversa de proteïnes, caracteritzada per la presència del Seleni (Se), en forma de l'amino àcid atípic, la selenocisteïna (Sec). La selenocisteïna, coneguda com l'amino àcid 21, és similar a la cisteïna (Cys) amb un àtom de seleni en lloc de sofre (S). Les selenoproteïnes són els responsables majoritaris dels efectes biològics del seleni i s'ha observat que poden estar implicades en la infertilitat masculina, el càncer, algunes malalties coronàries,l'activació de virus latents i l'envelliment. La selenocisteïna es codifica pel codó UGA, normalment
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43

Oranzie, Marlon. "Electrochemical Aptasensing of B-Type Natriuretic Peptide-A Biomarker for Myocardial Infarction." University of the Western Cape, 2019. http://hdl.handle.net/11394/7707.

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>Magister Scientiae - MSc<br>infarction (MI) affects many parts of the western world and in South Africa alone it is estimated that MI is responsible for 1 in 6 deaths (17.3%). Traditional diagnostic methods for MI include an electrocardiograms and blood tests. The problem with these diagnostic methods are that they are time consuming, require large sample volumes, expensive equipment and complicated machinery. To achieve early detection of MI the discovery of specific, sensitive and reliable biomarkers are required. Brain natriuretic peptide (BNP) has been identified as a reliable biomarker f
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Bahng, Hee-Jeong. "Antioxidants as Risk Factors for Gingival Bleeding." VCU Scholars Compass, 2004. http://scholarscompass.vcu.edu/etd/1516.

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Background: Studies of gingival bleeding and the effects of antioxidants on extracellular matrix and immunologic and inflammatory responses provide a rationale for hypothesizing that antioxidants reduce the risk for gingival bleeding.Methods: This study evaluated the role of antioxidants as contributing risk factors for gingival bleeding utilizing the Third National Health and Nutrition Examination Survey (NAHNES III). A sample of 18,825 adults (20 to ≥ 90 years of age), with dental measurement and assessment of serum levels of antioxidants were included in the study. Gingival bleeding was def
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Paschoal, Juliana Jorge. "Efeito da dieta contendo alta inclusão de soja extrusada e fonte orgânica de selênio sobre a composição, teor de CLA, perfil de ácidos graxos e estabilidade oxidativa do leite de vacas holandesas." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/74/74131/tde-05062007-082323/.

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A formulação de dietas para ruminantes pode alterar o perfil de ácidos do leite, potencializando o valor nutritivo e nutracêutico do mesmo. Estas alterações podem, no entanto, aumentar a susceptibilidade do leite à oxidação, perdendo qualidade em sabor e tempo de prateleira. O objetivo deste trabalho consistiu em avaliar o efeito do fornecimento de dieta com alto teor de soja integral extrusada, associada ou não à suplementação com selênio orgânico, sobre a produção, a composição, a concentração de CLA, o perfil de ácidos graxos e a estabilidade oxidativa do leite. Vinte e quatro vacas holande
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Burns, Kristi Lee. "An exploration of biochemistry including biotechnology, structural characterization, drug design, and chromatographic analyses." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/29593.

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Thesis (Ph. D.)--Chemistry and Biochemistry, Georgia Institute of Technology, 2007.<br>Committee Chair: Sheldon W. May ; Committee Members: Donald F. Doyle, Leslie T. Gelbaum, Stanley H. Pollock, and James Powers. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Wu, Jia-Ying, and 吳佳螢. "Rosmarinic acid alleviated selenite-induced cataract in rats." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/493n48.

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碩士<br>環球科技大學<br>生物技術研究所<br>105<br>Cataracts are the most common cause of human blindness worldwide, and their incidence is likely to increase as the environmental variation. Cataract is caused by mutation of lens-specific proteins which, the infection, the flesh wound or other diseases cause, can let the crystalline lens of the lens be muddy. In the present study, the aim was to evaluate the protection effects on sodium selenite-induced cataractogenesis. The rosemary acid (Rosmarinic acid, is called RA) is one kind of water-soluble natural phenol acids compound which the separation obtains fro
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48

Jasperse, Craig Peter. "The chemistry of isoselenazolidin-3-ones and a selenenic acid." 1987. http://catalog.hathitrust.org/api/volumes/oclc/16147966.html.

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林基福. "Synthesis and biological evaluation of selenium-containing phenoleic acid ester derivatives." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/75197146576281167797.

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Jiang, Sibo. "Novel Selenium-modified Nucleic Acids For Structural and Functional Studies." 2014. http://scholarworks.gsu.edu/chemistry_diss/92.

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Nucleic acids, as one of the most important macromolecules in living systems, play critical roles in storing, transferring, regulating genetic information, directing proteins synthesis, and catalysis. Understanding the structure of nucleic acid can bring us valuable information for mechanistic study and for drug discovery as well. Among all experimental methods, X-ray crystallography is the most powerful tool in structural biology study to reveal the 3D structure of macromolecules, which has provided over 80% of the highly detailed structural information to date. However, this great technology
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