Academic literature on the topic 'Selenium – Therapeutic use'

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Journal articles on the topic "Selenium – Therapeutic use"

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Duntas, Leonidas H., and Alicja Hubalewska-Dydejczyk. "Selenium and Inflammation— Potential Use and Future Perspectives." US Endocrinology 11, no. 02 (2015): 97. http://dx.doi.org/10.17925/use.2015.11.02.97.

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The essential trace element selenium (Se) is constitutively incorporated as selenocysteine, in proteins, among others in antioxidative selenoproteins, such as glutathione peroxidase(s) and thioredoxin reductase. Since chronic inflammation is thought to deplete Se stores in the body, Se supplementation should be considered in prolonged inflammatory states, Se being the trace element the most affected in chronic or low-grade inflammation. Se administration might also be beneficial in bacterial and viral diseases as well as metabolic and autoimmune diseases. In order to maintain a Se steady state
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Hubalewska-Dydejczyk, Alicja, Leonidas Duntas, and Aleksandra Gilis-Januszewska. "Pregnancy, thyroid, and the potential use of selenium." Hormones 19, no. 1 (2019): 47–53. http://dx.doi.org/10.1007/s42000-019-00144-2.

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Abstract The management of pregnant women is a major concern of health care around the world. There is growing evidence regarding the influence of selenium (Se) on pregnancy and fetus outcomes. However, due to as yet insufficient evidence, lack of measurable markers to assess the effect of Se supplementation on the human metabolism, and Se’s narrow therapeutic index, the majority of experts and the current guidelines published by several scientific societies do not recommend the use of Se in pregnancy and in women of childbearing age. Further research based on well-designed studies, including
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Janka, Vašková, Kočan Ladislav, Firment Jozef, and Vaško Ladislav. "Restoration of antioxidant enzymes in the therapeutic use of selenium in septic patients." Wiener klinische Wochenschrift 125, no. 11-12 (2013): 316–25. http://dx.doi.org/10.1007/s00508-013-0371-x.

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Achibat, Hanane, Nohad A. AlOmari, Federica Messina, Luca Sancineto, Mostafa Khouili, and Claudio Santi. "Organoselenium Compounds as Phytochemicals from the Natural Kingdom." Natural Product Communications 10, no. 11 (2015): 1934578X1501001. http://dx.doi.org/10.1177/1934578x1501001119.

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Selenium is naturally present in soils but it is also produced by pollution from human activities into the environment. Its incorporation into plants affords organoselenium metabolites that, depending on the nature of the molecules and the plant species, can be incorporated into proteins, stored or eliminated by volatilization. The possibility to use the selenium metabolism of some plants as a method for bioremediation and, at the main time, as a source of selenated phytochemicals is here discussed taking into consideration the growing interest in organic selenium derivatives as new potential
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Mirdayani, Eli, Irma M. Puspitasari, Rizky Abdulah, and Anas Surbanas. "Selenium sebagai Suplemen Terapi Kanker: Sebuah Review." Indonesian Journal of Clinical Pharmacy 8, no. 4 (2019): 301. http://dx.doi.org/10.15416/ijcp.2019.8.4.301.

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Selenium merupakan unsur mikronutrien yang penting bagi kesehatan manusia. Di dalam tubuh, selenium tersebar di semua organ dalam bentuk senyawa terkonjugasi protein (selenoprotein). Senyawa selenoprotein setidaknya mengandung selenosistein yang terdiri dari asam amino sistein. Senyawa selenoprotein pada umumnya bersifat antioksidan. Selenium dihubungkan dengan pengaruhnya terhadap kesehatan manusia termasuk beberapa jenis penyakit kanker. Studi penggunaan suplementasi selenium pada terapi kanker dengan radiasi dan kemoterapi menunjukan peningkatan kadar selenium pada plasma, meningkatkan efek
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Gong, Guifang, Bailing Fu, Caixin Ying, et al. "Targeted delivery of paclitaxel by functionalized selenium nanoparticles for anticancer therapy through ROS-mediated signaling pathways." RSC Advances 8, no. 70 (2018): 39957–66. http://dx.doi.org/10.1039/c8ra07539e.

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Lanzolla, Giulia, Claudio Marcocci, and Michele Marinò. "Oxidative Stress in Graves Disease and Graves Orbitopathy." European Thyroid Journal 9, Suppl. 1 (2020): 40–50. http://dx.doi.org/10.1159/000509615.

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Oxidative stress is involved in the pathogenesis of Graves hyperthyroidism (GH) and Graves orbitopathy (GO) and an antioxidant approach has been proposed for both. In GH, a disbalance of the cell redox state is associated with thyroid hyperfunction and antithyroid medications may reduce oxidative stress. Tissue hypoxia participates in the pathogenesis of GO, and oxygen free radicals are involved in the typical changes of orbital tissues as reported by in vitro and clinical studies. Antioxidant agents, especially selenium, have been proposed as a therapeutic option for GH and GO. A clinical stu
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Truong, Linh B., David Medina-Cruz, Ebrahim Mostafavi, and Navid Rabiee. "Selenium Nanomaterials to Combat Antimicrobial Resistance." Molecules 26, no. 12 (2021): 3611. http://dx.doi.org/10.3390/molecules26123611.

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The rise of antimicrobial resistance to antibiotics (AMR) as a healthcare crisis has led to a tremendous social and economic impact, whose damage poses a significant threat to future generations. Current treatments either are less effective or result in further acquired resistance. At the same time, several new antimicrobial discovery approaches are expensive, slow, and relatively poorly equipped for translation into the clinical world. Therefore, the use of nanomaterials is presented as a suitable solution. In particular, this review discusses selenium nanoparticles (SeNPs) as one of the most
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Pillay, Nikita Simone, Aliscia Daniels, and Moganavelli Singh. "Folate-Targeted Transgenic Activity of Dendrimer Functionalized Selenium Nanoparticles In Vitro." International Journal of Molecular Sciences 21, no. 19 (2020): 7177. http://dx.doi.org/10.3390/ijms21197177.

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Current chemotherapeutic drugs, although effective, lack cell-specific targeting, instigate adverse side effects in healthy tissue, exhibit unfavourable bio-circulation and can generate drug-resistant cancers. The synergistic use of nanotechnology and gene therapy, using nanoparticles (NPs) for therapeutic gene delivery to cancer cells is hereby proposed. This includes the benefit of cell-specific targeting and exploitation of receptors overexpressed in specific cancer types. The aim of this study was to formulate dendrimer-functionalized selenium nanoparticles (PAMAM-SeNPs) containing the tar
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Bodnar, O. I., H. B. Kovalska, O. Ya Lukashiv та V. V. Grubinko. "ОЦІНКА БІОЛОГІЧНОЇ ДІЇ ЕЛЕМЕНТВМІСНИХ ЛІПІДНИХ КОМПЛЕКСІВ З CHLORELLA VULGARIS НА ФУНКЦІОНАЛЬНИЙ СТАН ЗДОРОВИХ ЩУРІВ". Scientific Issue Ternopil Volodymyr Hnatiuk National Pedagogical University. Series: Biology 80, № 3-4 (2020): 50–62. http://dx.doi.org/10.25128/2078-2357.20.3-4.7.

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Chlorella is one of the most promising species of algae, which is widely cultivated for the industrial production of nutraceuticals in the form of tablets or powder. The value of Chlorella is primarily due to the high content of proteins and lipids (51–58 % and 20–23 % of dry weight respectively), carotenoids and an almost complete set of vitamins. At the same time, in the process of cultivation, a method was developed to enrich algobiomass and its individual components (primarily the lipid fraction) with selenium, zinc, chromium, as important regulatory trace elements.
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Dissertations / Theses on the topic "Selenium – Therapeutic use"

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Murphy, Stephanie A. "Effects of selenium and vitamin B-6 on growth of chemically- induced transplanted tumors in BALB/c inbred mice." Thesis, Virginia Tech, 1989. http://hdl.handle.net/10919/43906.

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Male weanling inbred, mice were inoculated with fibrosarcoma cells (hindquarter) originally produced by 2-methylcholanthrene. Before inoculation, mice were randomly divided into three groups of 24 and one of 12 (control). After a one week acclimation period, each group was fed a diet containing either suboptimal vitamin B-6, 0.5 mg/kg diet; adequate, 7.0 mg/kg diet; or excess, 100 mg/kg diet. Controls were fed the adequate vitamin. B-6 diet. Twenty-four hours after tumor cell inoculation, a series of sodium selenite injections (0.5 μg/.10 mL) were given to half of each treatment group and
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"Induction of apoptosis in selected human cancer cells by organoselenium compounds, ruthenium compounds and selenium containing ruthenium complexes." 2013. http://library.cuhk.edu.hk/record=b5884433.

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Liu, Yanan.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2013.<br>Includes bibliographical references (leaves 87-98).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstracts also in Chinese.
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"Selenocystine-induced apoptosis in human leukemia Sup-T₁ cells." 2010. http://library.cuhk.edu.hk/record=b5894398.

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Wong, Wing Yin.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2010.<br>Includes bibliographical references (leaves 90-105).<br>Abstracts in English and Chinese.<br>Acknowledgements --- p.i<br>Abstract --- p.iii<br>Abstract (Chinese Version) --- p.v<br>Table of Contents --- p.vi<br>List of Figures --- p.ix<br>List of Abbreviations --- p.xi<br>Chapter Chapter 1 --- General Introduction<br>Chapter 1.1 --- Overview of cancer --- p.1<br>Chapter 1.2 --- Acute lymphoblastic leukemia --- p.3<br>Chapter 1.2.1 --- T-cell acute lymphoblastic leukemia --- p.5<br>Chapter 1.2.1.1 --- Chemot
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"Selenocystine induces mitochondrial-mediated apoptosis in breast carcinoma MCF-7 cells and melanoma A-375 cells with involvement of p53 phosphorylation and reactive oxygen species." Thesis, 2008. http://library.cuhk.edu.hk/record=b6074646.

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Additionally, we showed that SeC induced S-phase arrest in MCF-7 cells associated with a marked decrease in the protein expression of cyclin A, D1 and D3 and cyclin-dependent kinases (CDK) 4 and 6, with concomitant induction of p21waf1/Cip1, p27Kip1 and p53. Expose of MCF-7 cells to SeC resulted in delayed onset of apoptosis as evidenced by caspase activation, PARP cleavage and DNA fragmentation. SeC treatment also triggered the activation of JNK, p38 MAPK, ERK and Akt phosphorylation. Inhibitors of ERK (U0126) or Akt (LY294002), but not JNK (SP600125) and p38 MAPK (SB203580), significantly su
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Yu, Qing 1966. "Effect of dietary fluoride on selenite toxicity in the rat." Thesis, 1992. http://hdl.handle.net/1957/27040.

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Two factorial experiments were conducted to determine if high dietary fluoride would inhibit selenite toxicity in rats. In each study, two levels of selenite (0.05 and 5 mg/kg diet) were matched against two levels of fluoride (1 and 150 mg/kg diet) for either 6 or 8 weeks. Fluoride failed to prevent the depressive effect of selenite on food intake and body weight gain in either study. Although liver selenium concentration was slightly (15%) but significantly (P < 0.005) reduced when the highest fluoride and selenium level were combined in the first study, this effect could not be repeated. Th
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Books on the topic "Selenium – Therapeutic use"

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Seale, Lucia A. Role of selenium in mitigating mercury toxicity. Nova Science Publishers, 2011.

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International Symposium on Selenium in Biology and Medicine (3rd 1984 Beijing, China). Selenium in biology and medicine: Proceedings of the Third International Symposium on Selenium in Biology and Medicine, held May 27-June 1, 1984, Xiangshan (Fragance Hills) Hotel Beijing, People's Republic of China. Van Nostrand Reinhold, 1987.

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Passwater, Richard A. Selenium against cancer and aids: The trace mineral that can make a life-or-death difference-- and that many of us lack. Keats Pub., 1996.

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1982-, Hovde Scott Curtiss, and North Dakota State University. Dept. of Agribusiness and Applied Economics., eds. Identifying market preferences for high selenium beef. Dept. of Agribusiness and Applied Economics, North Dakota State University, 2007.

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F, Combs Gerald, ed. Selenium in biology and medicine. Van Nostrand Reinhold, 1987.

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Spallholz, Julian E., G. F. Combs, and O. A. Levander. Selenium in Biology and Medicine: Proceedings of the Third International Symposium on Selenium in Biology and Medicine, Parts A and B/Third Internat. A V I Publishing Company, 1987.

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Diversity of Selenium Functions in Health and Disease. Taylor & Francis Group, 2015.

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Mu, Ying, Guimin Luo, and Junqiu Liu. Selenoproteins and Mimics. Springer, 2012.

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Selenoproteins And Mimics. Springer, 2012.

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Yu, Qing. Effect of dietary fluoride on selenite toxicity in the rat. 1991.

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Book chapters on the topic "Selenium – Therapeutic use"

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Jinpeng, Xu. "Selenium and Kashin-Beck Disease." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_61.

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Calomme, M. R., V. Th Ramaekers, W. Makropoulos, and D. A. Vanden Berghe. "Selenium Deficiency Triggering Intractable Seizures." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_62.

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Le Moël, G., T. Gousson, A. Dauvergne, et al. "Selenium and Antioxidant Factors in Crohn’s Disease." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_24.

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Ducros, V., P. Faure, M. Ferry, F. Couzy, I. Biajoux, and A. Favier. "Influence of Nutritional Status on Selenium Pharmacokinetics." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_5.

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Whanger, P. D. "The Relationship of Dietary Selenium to Carcinogenesis." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_58.

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da Silva, C., J. Poupon, P. J. Guillausseau, and P. Chappuis. "Serum Selenium, Micro and Macrovascular Complications in Diabetic Patients." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_26.

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Zloch, Z. "The Antioxidative Role of Selenium in Cadmium Chronic Intoxication." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_38.

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Ortuño, Josefina, Gaspar Ros, María Jesús Periago, Carmen Martínez, and Ginés López. "Selenium Availability and Protein Digestibility in Homogenised Infant Foods." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_9.

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Bauer, Ph, F. Belleville-Nabet, E. Vauthier, et al. "Metabolism of Selenium in a Model of Mesenteric Ischemia-Reperfusion Injury." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_39.

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Viegas-Crespo, A. M., M. L. Pavão, M. L. Mira, I. Torres, M. J. Halpern, and J. Nève. "Comparison of Serum Selenium Levels in Inhabitants from Different Portuguese Regions." In Therapeutic Uses of Trace Elements. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0167-5_60.

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