Relevant bibliographies by topics / Selenomethionin

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Selenomethionin'

Author: Grafiati
Published: 4 June 2021
Last updated: 15 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Selenomethionin.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Selenomethionin"

1

Smith, Janet L., and Andrew Thompson. "Reactivity of selenomethionin – dents in the magic bullet?" Structure 6, no. 7 (July 1998): 815–19. http://dx.doi.org/10.1016/s0969-2126(98)00083-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

AVOSCAN, L., H. KHODJA, M. CARRIÈRE, J. COVÈS, and B. GOUGET. "PIXE ANALYSES OF THE SOLUBLE AND MEMBRANE SE-CONTAINING PROTEINS EXTRACTED FROMCUPRIAVIDUS METALLIDURANSCH34 AFTER SELENIUM OXIDES CHALLENGE." International Journal of PIXE 18, no. 03n04 (January 2008): 91–99. http://dx.doi.org/10.1142/s0129083508001430.

Full text
Abstract:
The soil bacterium Cupriavidus metallidurans CH34 resist selenite by reducing it into the insoluble and less toxic elemental selenium. Two mechanisms of reduction of selenium oxides in C. metallidurans CH34 were highlighted: assimilation leading to organic species and detoxification leading to precipitation of selenite in nanoparticules of elemental selenium. The alkyl selenide detected as an intermediate product during assimilation of selenite or as the major accumulated chemical form during assimilation of selenate was identified as selenomethionine.Soluble and membrane proteins were extracted from C. metallidurans CH34 submitted to selenium oxides challenge. After separation by SDS-PAGE, µPIXE analyses were used for Se identification and quantification at a micrometer scale. The profiles of Se distribution in the different samples suggest a non-specific incorporation of selenium probably reflecting the incorporation of selenomethionin in place of the naturally occurring methionin.
APA, Harvard, Vancouver, ISO, and other styles
3

Kelly, Bernard T., Stephen C. Graham, and David J. Owen. "Using selenomethionyl derivatives to assign sequence in low-resolution structures of the AP2 clathrin adaptor." Acta Crystallographica Section D Structural Biology 72, no. 3 (March 1, 2016): 336–45. http://dx.doi.org/10.1107/s2059798315021580.

Full text
Abstract:
Selenomethionine incorporation is a powerful technique for assigning sequence to regions of electron density at low resolution. Genetic introduction of methionine point mutations and the subsequent preparation and crystallization of selenomethionyl derivatives permits unambiguous sequence assignment by enabling the placement of the anomalous scatterers (Se atoms) thus introduced. Here, the use of this approach in the assignment of sequence in a part of the AP2 clathrin adaptor complex that is responsible for clathrin binding is described. AP2 plays a pivotal role in clathrin-mediated endocytosis, a tightly regulated process in which cell-surface transmembrane proteins are internalized from the plasma membrane by incorporation into lipid-enclosed transport vesicles. AP2 binds cargo destined for internalization and recruits clathrin, a large trimeric protein that helps to deform the membrane to produce the transport vesicle. By selenomethionine labelling of point mutants, it was shown that the clathrin-binding site is buried within a deep cleft of the AP2 complex. A membrane-stimulated conformational change in AP2 releases the clathrin-binding site from autoinhibition, thereby linking clathrin recruitment to membrane localization.
APA, Harvard, Vancouver, ISO, and other styles
4

& Al-Hassani, Ali. "TEMPERATURE AND SOME BLOOD TRAITS RESPONSE TO ORGANIC AND INORGANIC SELENIUM ADDED TO THE BROILER DIET REARED AT HIGH TEMPERATURES." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 51, no. 3 (June 25, 2020): 734–43. http://dx.doi.org/10.36103/ijas.v51i3.1027.

Full text
Abstract:
This study was conducted at the poultry farm -Animal Production Department/ College of Agricultural Engineering Sciences- University of Baghdad, for the period from 2018/8/17 to 2018/9/28, in order to study the effect of adding inorganic and organic selenium to the broiler diets reared at high temperatures in the physiological performance. A 420 un-sexed chicks of breed (Ross 308) were used in the experiment as a one-day old and with weight rate of 36.4g. The chicks were distributed randomly and equally on 7 treatments, each one included 3 replicates at 20 chicks/replicate. The experiment included the following treatments : T1,T2, and T3 as organic selenium treatments which are selenomethionin with a concentration of 0.3, 0.6, and 0.9 mg/kg feed, respectively, and T4, T5, and T6 as inorganic selenium treatments in the form of Sodium Selenite compound at a concentrations of 0.3, 0.6, and 0.9 mg/kg feed, respectively, and T7 control treatment without any addition of selenium, while the chicks were bred at a high temperature rate of 22.5 - 43.9 ℃. Organic and inorganic Selenium have not shown a clear effect in reducing body temperature compared to the control treatment, as well as, a high significant decreasing in the blood Hematocrit and Hemoglobin concentration for inorganic Selenium treatments compared to the organic Selenium and control treatments. Finally, The results indicated that there were no significant differences in the cholesterol and glucose levels in blood of organic and inorganic Selenium and control treatments.
APA, Harvard, Vancouver, ISO, and other styles
5

Kitajima, Toshihiko, Emi Yagi, Tomomi Kubota, Yasunori Chiba, Satoshi Nishikawa, and Yoshifumi Jigami. "Use of novel selenomethionine-resistant yeast to produce selenomethionyl protein suitable for structural analysis." FEMS Yeast Research 9, no. 3 (May 2009): 439–45. http://dx.doi.org/10.1111/j.1567-1364.2009.00484.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Ruszel, Kinga, Piotr Pokorski, and Barbara Nieradko-Iwanicka. "Controversies about selenium supplementation." Polish Journal of Public Health 131, no. 1 (January 1, 2021): 20–26. http://dx.doi.org/10.2478/pjph-2021-0005.

Full text
Abstract:
Abstract Introduction. Selenium (Se) is a trace element found mainly in meat, seafood, nuts and grains. Se is found in selenoproteins such as selenocystein or selenomethionin. A well balanced diet provides enough Se. Many regulatory and metabolic enzymes contain Se as their component, which is why Se supplementation is used in the treatment as well as prevention of multiple disorders. Se may, however, be toxic if overdosed. Aim. The aim of this review is to summarize the data about functions of Se in human body and to discuss its use in treatment and prevention of diseases. Materials and methods. The search was conducted using the PubMed and Google Scholar databases in March and April 2020. The key words used were: ‘selenium’, ‘cardiovascular disease’, ‘selenium supplementation’, ‘Keshan disease’, ‘source of selenium’. A total of 68 articles were analysed. Results. The first cases of chronic Se deficiency cases were documented 85 years ago in China. The patients with cardiomyopathy, extensive fibrosis and degenerative changes in the heart were diagnosed with Keshan disease. Human selenoproteonome consists of at least 25 selenoproteins. Se plays a role in immunity and metabolism via its role in functioning of numerous enzymes: glutathione peroxidase, thioredoxine and methionine sulfoxide reductase, methionine-sulfoxide reductase B1. Se plays a role in glucose homeostasis, Alzheimer’s disease, thyroid disorders, infectious, inflammatory diseases, vascular diseases and fertility. Conclusion. Se deficiency increases the risk of Keshan disease, but there is not enough evidence to recommend its supplementation for prevention of cardiovascular disease. However, Se status is important part of health assessment. Se supplementation should not exceed the dose of 55μg/day.
APA, Harvard, Vancouver, ISO, and other styles
7

Giraud, Marie-France, Helen J. McMiken, Gordon A. Leonard, Paul Messner, Chris Whitfield, and James H. Naismith. "Overexpression, purification, crystallization and preliminary structural study of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD), the fourth enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar Typhimurium." Acta Crystallographica Section D Biological Crystallography 55, no. 12 (December 1, 1999): 2043–46. http://dx.doi.org/10.1107/s0907444999012251.

Full text
Abstract:
L-Rhamnose is an essential component of the cell wall of many pathogenic bacteria. Its precursor, dTDP-L-rhamnose, is synthesized from α-D-glucose-1-phosphate and dTTP via a pathway requiring four distinct enzymes: RmlA, RmlB, RmlC and RmlD. RmlD catalyses the terminal step of this pathway by converting dTDP-6-deoxy-L-lyxo-4-hexulose to dTDP-L-rhamnose. RmlD from Salmonella enterica serovar Typhimurium has been overexpressed in Escherichia coli. The recombinant protein was purified by a two-step protocol involving anion-exchange and hydrophobic chromatography. Dynamic light-scattering experiments indicated that the recombinant protein is monodisperse. Crystals of native and selenomethionine-enriched RmlD have been obtained using the sitting-drop vapour-diffusion method with polyethylene glycol as precipitant. Diffraction data have been collected from orthorhombic crystals of both native and selenomethionyl-derivatized protein, allowing tracing of the protein structure.
APA, Harvard, Vancouver, ISO, and other styles
8

Park, Jimin, Hyojin Kim, Suwon Kim, Daeun Lee, and Dong Hae Shin. "Expression and crystallographic studies ofD-glycero-β-D-manno-heptose-1-phosphate adenylyltransferase fromBurkholderia pseudomallei." Acta Crystallographica Section F Structural Biology Communications 73, no. 2 (January 19, 2017): 90–94. http://dx.doi.org/10.1107/s2053230x16020537.

Full text
Abstract:
The Gram-negative bacteriumBurkholderia pseudomalleiis the causative agent of melioidosis. D-glycero-β-D-manno-Heptose-1-phosphate adenylyltransferase (HldC) is the fourth enzyme of the ADP-L-glycero-β-D-manno-heptose biosynthesis pathway, which produces an essential carbohydrate comprising the inner core of lipopolysaccharide. Therefore, HldC is a potential target of antibiotics against melioidosis. In this study, HldC fromB. pseudomalleihas been cloned, expressed, purified and crystallized. Synchrotron X-ray data from a selenomethionine-substituted HldC crystal were also collected to 2.8 Å resolution. The crystal belonged to the primitive triclinic space groupP1, with unit-cell parametersa= 74.0,b= 74.0,c= 74.9 Å, α = 108.4, β = 108.4, γ = 108.0°. Eight protomers are present in the unit cell and three out of five selenomethionines were found in each protomer using thePHENIXsoftware suite. A full structural determination is in progress to elucidate the structure–function relationship of the protein.
APA, Harvard, Vancouver, ISO, and other styles
9

Kachuee, R., M. Moeini, and M. Souri. "Effects of organic and inorganic selenium supplementation during late pregnancy on colostrum and serum Se status, performance and passive immunity in Merghoz goats." Animal Production Science 54, no. 8 (2014): 1016. http://dx.doi.org/10.1071/an13150.

Full text
Abstract:
This study was conducted to determine the effects of organic and inorganic selenium (Se) supplementation during late pregnancy on serum Se status, colostrum, performance and passive immunity in Merghoz goats in Iran. Thirty Merghoz goats (30 ± 3 kg) were given the same basal diet containing 0.11 mg Se/kg DM and were randomly allocated to one of three dietary treatments in a randomised complete block design. Four weeks before the expected kidding, the basal diets were supplemented with 0 (control), 0.3 mg Se/head.day in the form of L-selenomethionin (Se-Met) and 0.3 mg Se/head.day in the form of sodium selenite. Blood samples were collected from the goats in three phases: (1) a couple of days before starting the supplementation; (2) before the expected kidding; and (3) on the day of kidding. Blood samples were also taken from the newborn kids from the jugular vein at birth and 7 days of age. The serum Se and immunoglobulin G (IgG) concentrations, the white blood cells (WBC) and differential leukocyte counts were measured. The reproductive parameters such as the number of kids born per kidding, total weight of kids born per goat mating, the pregnancy period and kid birthweights were determined. The results indicated that the serum Se concentration increased in supplemented goats compared with controls. The Se concentrations also significantly increased in the colostrum of treated goats (P < 0.05). Similarly, serum Se concentrations in kids of treated goats were increased at birth. On the other hand, colostrum and daily milk production were not affected by Se supplementation. Likewise, the change in the mean serum IgG levels was not different among goats and kids (P > 0.05). However, the WBC, neutrophil and lymphocyte counts were higher in the kids of goats in the Se-Met group compared with the control group on the day of birth and 7 days of age (P < 0.05). It seemed that Se-Met could have influenced the lamb’s immunity at birth and 7 days of age. By contrast, selenite has not affected the performance and passive immunity in Merghoz goats.
APA, Harvard, Vancouver, ISO, and other styles
10

Kitajima, Toshihiko, and Yasunori Chiba. "Selenomethionine metabolism and its toxicity in yeast." BioMolecular Concepts 4, no. 6 (December 1, 2013): 611–16. http://dx.doi.org/10.1515/bmc-2013-0033.

Full text
Abstract:
AbstractThe importance of selenium for organisms can be explained by its existence as selenocysteine in the catalytic centers of glutathione peroxidase and thioredoxin reductase. Another selenoamino acid, selenomethionine, is the major form of selenium in foods, and organisms that require selenium as a nutrient directly metabolize selenomethionine to a reactive form of selenium or store it in general proteins. Selenium is recognized as an essential nutrient for human and animal health; however, its excessive uptake harms mammals and the cytotoxic mechanism of selenium remains unclear. Recent progress in the development of selenium-enriched yeast and selenomethionine-resistant mutant to produce selenomethionine-containing proteins for X-ray crystallography has provided new insights into the molecular mechanism of selenomethionine toxicity. In this review, we describe the metabolism of seleno-compounds in yeast and discuss the cytotoxicity caused by selenomethionine against yeast from a metabolic viewpoint.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Selenomethionin"

1

Klaus, Viola [Verfasser], and Andrea [Akademischer Betreuer] Hartwig. "Die Rolle von p53 in der zellulären Antwort auf Natriumselenit und Selenomethionin / Viola Klaus. Betreuer: Andrea Hartwig." Berlin : Technische Universität Berlin, 2010. http://d-nb.info/1066546134/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Gojkovic, Živan. "Produkce, charakterizace a využití biomasy různého původu." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2014. http://www.nusl.cz/ntk/nusl-233391.

Full text
Abstract:
Úprava biomasy je jedním z nejdůležitějších problémů v moderních přírodních vědách, protože je základní kategorií týkající se zemědělství, potravinářství, ekologie, zpracování odpadu a biotechnologie. Ať už živočišného, rostlinného nebo mikrobiálního původu, biomasa představuje obrovský zdroj surovin jako potravin, čistých chemikálií, bioaktivních molekul atd., jejichž izolace, charakterizace a formulace může vést k zajímavým novým produktům určeným pro lidskou spotřebu, nebo jako nový materiál v biomedicíně. Předložená studie byla zaměřena na výzkum dvou druhů biomasy - kuřecí kůže jako zdroje kolagenu t a biomasy mikrořasy Chlorella sorokiniana obohacené selenomethioninem (SeMet). V první části práce byl z kuřecí kůže izolován, identifikován a charakterizován kolagen typu I. Molekulární vlastnosti kuřecího kolagenu byly analyzovány a srovnány s jinými kolageny z živočišných kůží. Pro molekulární charakterizaci kolagenu byla použita viskosimetrie a ultrazvuková spektroskopie. Ultrazvukovou spektroskopií bylo zjištěno, že disagregace a zkapalňování hovězího kolagenu začíná při teplotě 40 °C, zatímco u kuřecího kolagenu začíná až při 50 °C. Viskosimetrie dále potvrdila vyšší tepelnou stabilitu kolagenu z kuřecí kůže, jeho denaturační teplota byla 50 °C, což je rovněž o deset stupňů více než u hovězího kolagenu. Kuřecí kolagen obsahuje dvakrát vyšší množství lysinu, což poskytuje tepelnou stabilitu kolagenu. Na základě získaných výsledků lze říci, že vzhledem ke své vysoké tepelné stabilitě a vhodnému aminokyselinovému složení, kuřecí kůže může být použita jako alternativní zdroj kolagenu typu I s aplikacemi v potravinářském průmyslu a biomedicíně. Druhá část práce byla zaměřena na obohacení biomasy zelené mikrořasy C. sorokiniana selenomethioninem. Experimentální část byla provedena v Laboratoři biotechnologie řas na Univerzitě Huelva ve Španělsku. Cílem první části experimentů bylo studovat vliv selenu na životaschopnost řas, morfologii buněk a akumulaci SeMet v biomase mikrořasy kultivované v dávkových kulturách. Subletální koncentrace Se v živném médiu, 40 mgL-1 (212 M), snížila rychlost růstu o 25 % ve srovnání s kontrolní kulturou. Hodnota EC50 45 mgL-1 (238,2 M) byla stanovena pro selenan. Ultrastrukturální studie ukazovaly na strukturální změny chloroplastu (granulární stroma, redukce thylakoid). Elektroforéza proteinů z biomasy mikrořasy ukazuje, že Se ovlivňuje expresi genu enzymu Rubisco. C. sorokiniana byla schopna akumulovat až 140 mgkg-1 SeMet během 120 h kultivace. Další část experimentální práce byla zaměřena na obohacování biomasy mikrořasy C. sorokiniana selenomethioninem během kontinuální kultivace s použitím 2,2 L bioreaktoru v kultivačním médiu s přídavkem koncentrace selenu v rozmezí od 5 do 50 mgL-1. C. sorokiniana rostla stejně ve všech testovaných koncentracích selenu kromě koncentrace 50 mgL1, která byla již po krátké době kultivace letální. Během kontinuální kultivace se 40 mgL-1 selenu, bylo získáno maximálně 246 gL-1 selenomethioninu denně. Výsledky ukazují, že kultivace v dávkových kulturách a dlouhodobá kontinuální kultivace mikrořasy C. sorokiniana pro získaní biomasy obohacené SeMet je možná pečlivým výběrem podmínek kultivace a subletálních koncentrací selenu v živném médiu.
APA, Harvard, Vancouver, ISO, and other styles
3

Waschulewski, Ingo Herbert 1962. "Effect of dietary methionine on selenomethionine metabolism and utilization for selenoproteins." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276933.

Full text
Abstract:
The effects of dietary methionine (Met) on the utilization of selenium (Se) from stored tissue Se and dietary selenomethionine (SeMet) for glutathione peroxidase (GSH-Px) synthesis were studied in male rats. Plasma, liver and muscle Se significantly increased when rats were fed 0.5 mg Se/kg diet as SeMet in a Met-deficient diet for 21 d, whereas tissue GSH-Px activities decreased 43-50% during the SeMet supplementation period, suggesting that Se is deposited as SeMet in general body proteins. By calculation, a significant lower percentage of Se was associated with GSH-Px in Met-deficient as compared to Met-supplemented rats. Dietary Met supplementation increased the incorporation of 75Se from 75SeMet into specific rat selenoproteins in addition to liver GSH-Px. Overall, these results suggest that intact SeMet is preferentially incorporated non-specifically into general body proteins in Met-deficient rats, whereas with supplemental Met, more SeMet is degraded and the released Se used for specific selenoprotein synthesis. (Abstract shortened with permission of author.)
APA, Harvard, Vancouver, ISO, and other styles
4

Baines, Antonio Thomas. "The mechanism of action of the anticancer effects of selenomethionine on colon cancer." Diss., The University of Arizona, 2001. http://hdl.handle.net/10150/290479.

Full text
Abstract:
Selenomethionine, an organic derivative of selenium, has been found to be the predominate selenium component of the dietary cancer chemopreventive agent selenized yeast that has been shown to decrease the incidence and mortality rate of lung, colon, and prostate cancers. Another organic selenium derivative found in the selenized yeast is Se-methylselenocysteine. However, the mechanism of action of the anti-cancer effects of these selenium compounds has yet to be identified. To evaluate the effects of these compounds on growth of the cancer cell types mentioned earlier, various cancer cell lines were treated with either compound. Both selenium compounds were able to induce growth inhibition and alterations in the cell cycle, with selenomethionine being the most potent. Previously, our laboratory has shown that treating cancer cells with selenomethionine depleted polyamines. Polyamines are cations that are needed for various roles in growth and proliferation. To extend these findings to an in vivo model, we gave selenomethionine in the diet (1ppm and 2ppm) for 16 weeks to male F344 rats in the azoxymethane (AOM) rat colon carcinogenesis model. The results showed no significant changes in colonic polyamine levels, however, there were significant changes in the development of microadenomas between control and treated groups. Selenomethionine was able to decrease the promotional effects of colon carcinogenesis through a polyamine-independent mechanism. Next, we tested the hypothesis that selenomethionine might affect cell growth by mechanisms involving cyclooxygenases, specifically the inducible isoform COX-2. Cyclooxygenases (COX-1 and COX-2) are enzymes that metabolize arachidonic acid to various prostaglandins. The human adenocarcinoma cell lines HT-29 and HCA-7, that express variable levels of COX-2, were treated for up to 6 days with selenomethionine. Selenomethionine induced growth inhibition in both cell lines and decreased COX-2 protein expression in the treated groups. Also, prostaglandin (PG) E2 levels were decreased in both treated groups at the latter timepoints. The HCA-7 cell line had a dose and time-dependent decrease in RNA levels treated with selenomethionine, whereas, no effects were observed on RNA expression of the HT-29 cell line. In summary, selenomethionine has chemopreventive effects in colon carcinogenesis by potentially modulating COX-2 proteins in cancer cells.
APA, Harvard, Vancouver, ISO, and other styles
5

Gomes, Gabriela Roncada. "Suplementação com selênio orgânico nas dietas de tilápia do Nilo (Oreochromis niloticus) /." Jaboticabal : [s.n.], 2008. http://hdl.handle.net/11449/86697.

Full text
Abstract:
Orientador: Rodrigo Yudi Fujimoto
Banca: Claudinei da Cruz
Banca: Eduardo Makoto Onaka
Resumo: O Selênio é um mineral constituinte de uma série de enzimas antioxidantes que atuam protegendo as membranas celulares dos danos causados pelo processo de oxidação. Sua deficiência ou excesso na dieta pode resultar em depressão do crescimento e aumento da taxa de mortalidade. O objetivo deste estudo foi avaliar o efeito da suplementação da dieta em jovens de tilápia do Nilo (Oreochromis niloticus) com quatro níveis de selenometionina (0,25; 0,50; 1,0; e 1,5 mg Se/kg) e um grupo controle (0,0 mg Se/kg) no desempenho produtivo (ganho de peso, conversão alimentar aparente, taxa de crescimento específico e consumo de ração), nos índices hepatossomático e esplenossomático, na histopatologia do fígado, no índice de parasitismo por monogenea e na hematologia. O consumo de ração aumentou proporcionalmente ao nível de Se nas dietas. Os índices de desempenho produtivo não apresentaram diferenças significativas, no entanto, as concentrações intermediárias (0,25 e 0,50 mg Se/kg) aumentaram o ganho de peso, diminuíram a conversão alimentar e não apresentaram alterações significativas no estrutura morfofuncional do fígado. Não ocorreu diferença significativa para as variáveis hematológicas estudadas e para o índice de parasitismo por monogenea, porém, observou-se que nos níveis de 0,50 e 1,0 mg Se/kg o número de parasitos foi menor em relação às demais concentrações. Assim, pode-se concluir que a melhor suplementação está entre os níveis de 0,25 e 0,50 mg Se/kg de ração.
Abstract: Selenium is an important micronutrient for animals, essential for the normal life processes. This mineral is a constituent of the enzyme antioxidant glutathione peroxidase, of deiodinase and of thioredoxin reductase. The deficiency or toxic levels in feed can be result in growth depression and mortality. The objective of this study was to evaluate the selenomethionine effects for juveniles Nile tilapia (Oreochromis niloticus) on the growth performance (weight gain, index of alimentary conversion, specific growth rate, diet consumption and index of alimentary efficiency), hepatossomatic and esplenossomatic index, liver histopathology, parasitism and haematology, submitted to four levels of selenium in feed (0.25, 0.50, 1.0, and 1.5 mg Se/kg diet) and control group (0.0 mg Se/kg). The results did not show difference, however, the levels of 0.25 and 0.50 mg Se/kg improve the growth performances evaluated and did not show liver histopathology damage. No differences were observed in haematological parameters. The total count of monogeneans reduced in the levels of 0.50 and 1.0 mg Se/kg of diet but without differences due the elevated coefficient of variation. In conclusion the ideal supplementation level was between 0.25 and 0.50 mg Se/kg.
Mestre
APA, Harvard, Vancouver, ISO, and other styles
6

Gomes, Gabriela Roncada [UNESP]. "Suplementação com selênio orgânico nas dietas de tilápia do Nilo (Oreochromis niloticus)." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/86697.

Full text
Abstract:
Made available in DSpace on 2014-06-11T19:22:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-07-18Bitstream added on 2014-06-13T19:48:38Z : No. of bitstreams: 1 gomes_gr_me_jabo.pdf: 339770 bytes, checksum: dd4a8375e7eb01472c1aff691990e379 (MD5)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O Selênio é um mineral constituinte de uma série de enzimas antioxidantes que atuam protegendo as membranas celulares dos danos causados pelo processo de oxidação. Sua deficiência ou excesso na dieta pode resultar em depressão do crescimento e aumento da taxa de mortalidade. O objetivo deste estudo foi avaliar o efeito da suplementação da dieta em jovens de tilápia do Nilo (Oreochromis niloticus) com quatro níveis de selenometionina (0,25; 0,50; 1,0; e 1,5 mg Se/kg) e um grupo controle (0,0 mg Se/kg) no desempenho produtivo (ganho de peso, conversão alimentar aparente, taxa de crescimento específico e consumo de ração), nos índices hepatossomático e esplenossomático, na histopatologia do fígado, no índice de parasitismo por monogenea e na hematologia. O consumo de ração aumentou proporcionalmente ao nível de Se nas dietas. Os índices de desempenho produtivo não apresentaram diferenças significativas, no entanto, as concentrações intermediárias (0,25 e 0,50 mg Se/kg) aumentaram o ganho de peso, diminuíram a conversão alimentar e não apresentaram alterações significativas no estrutura morfofuncional do fígado. Não ocorreu diferença significativa para as variáveis hematológicas estudadas e para o índice de parasitismo por monogenea, porém, observou-se que nos níveis de 0,50 e 1,0 mg Se/kg o número de parasitos foi menor em relação às demais concentrações. Assim, pode-se concluir que a melhor suplementação está entre os níveis de 0,25 e 0,50 mg Se/kg de ração.
Selenium is an important micronutrient for animals, essential for the normal life processes. This mineral is a constituent of the enzyme antioxidant glutathione peroxidase, of deiodinase and of thioredoxin reductase. The deficiency or toxic levels in feed can be result in growth depression and mortality. The objective of this study was to evaluate the selenomethionine effects for juveniles Nile tilapia (Oreochromis niloticus) on the growth performance (weight gain, index of alimentary conversion, specific growth rate, diet consumption and index of alimentary efficiency), hepatossomatic and esplenossomatic index, liver histopathology, parasitism and haematology, submitted to four levels of selenium in feed (0.25, 0.50, 1.0, and 1.5 mg Se/kg diet) and control group (0.0 mg Se/kg). The results did not show difference, however, the levels of 0.25 and 0.50 mg Se/kg improve the growth performances evaluated and did not show liver histopathology damage. No differences were observed in haematological parameters. The total count of monogeneans reduced in the levels of 0.50 and 1.0 mg Se/kg of diet but without differences due the elevated coefficient of variation. In conclusion the ideal supplementation level was between 0.25 and 0.50 mg Se/kg.
APA, Harvard, Vancouver, ISO, and other styles
7

Zorzetto, Priscila Spinola. "Fontes de selênio na dieta de matrizes pesadas." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-31012018-151337/.

Full text
Abstract:
A nutrição para matrizes de frangos de corte tem como objetivo maximizar a produção de ovos e a qualidade da progênie subsequente e é considerada essencial para a melhora da produção e qualidade dos ovos. Os nutrientes transferidos para os ovos são importantes para o crescimento e desenvolvimento fisiológico do embrião. O organismo animal sofre constantemente ação do estresse oxidativo e o selênio (Se) é considerado um eficiente antioxidante natural que é essencial para matrizes de frangos de corte. Este estudo foi conduzido com matrizes de frango de corte alimentadas com duas fontes de Se (selenometionina - orgânica e selenito de sódio - inorgânico) para avaliar o seu desempenho produtivo, as características reprodutivas, a concentração de Se no ovo bem como o desempenho e rendimento de carcaça da progênie subsequente. Foram utilizadas 216 matrizes AP95 Aviagen de 55 a 65 semanas de idade, em delineamento inteiramente casualizado, com dois tratamentos e 27 repetições de quatro aves cada. Para o experimento com a progênie, foram utilizados 520 pintinhos mistos em delineamento inteiramente casualizado em um fatorial 2 x 2 (duas fontes de Se da dieta das matrizes e duas fontes de Se para dietas de frangos de corte - selenito de sódio e selenometionina) com quatro tratamentos, 13 repetições de 10 aves cada. As matrizes alimentadas com Se orgânico melhoraram a produção de ovos em comparação com o Se inorgânico (p = 0,038; p = 0,044). A concentração do Se no ovo e na clara foi maior para Se orgânico em comparação com o inorgânico (p <0,001; p <0,001). As taxas de fertilidade, bem como mortalidade embrionária, não sofreram efeito significativo ao se comparar as duas fontes. Não foram observadas diferenças entre a altura de albúmen, unidade Haugh e espessura da casca para a qualidade do ovo. O peso do ovo e coloração da gema foram estatisticamente diferentes (p=0,001; p=0,026) para fonte inorgânica comprada com a orgânica. A resistência a quebra do ovo foi melhor estatisticamente (p=0,007) para fonte orgânica. Não foram observadas interações entre a dieta da progênie e a dieta materna para nenhum dos critérios avaliados. Não foram observados efeitos da dieta materna, assim como da dieta da progênie sobre o consumo de ração, ganho de peso corporal e rendimento de carcaça e cortes. No entanto, a taxa de conversão alimentar foi melhor (p = 0,017) em frangos de corte provenientes de matrizes alimentadas com selenometiona. Assim, a selenometionina melhorou a produção e qualidade de ovos e propiciou maior transferência de Se para o ovo, principalmente na clara. Além disso, melhorou a conversão alimentar da progênie, devido a sua melhor biodisponibilidade.
The nutrition for broiler breeders has the objective of maximizing egg production and the quality of subsequent progeny. It is essential to improve the egg production and egg quality. The nutrients transferred to the eggs are important for growth and physiological development embryo. The animal organism is constantly suffering by oxidative stress. Selenium (Se) is considered an efficient natural antioxidant and has shown to be essential for broiler breeders. This trial was conducted using broiler breeders fed with two different sources of Se (organic - selenomethionine and inorganic - sodium selenite) to determinate performance, reproductive characteristics, Se concentration in egg as well as performance and carcass yield of the subsequent progeny. It was used 216 AP95 Aviagen broiler breeders, from 55 to 65 weeks of age, in completely randomized design with two treatments and 27 replications of four birds each. For subsequent progeny, it was used 520 straght-run chicks in a completely randomized design in a 2 x 2 factorial (two sources of Se for broiler breeders diets and two sources of Se for broilers diets- sodium selenite and selenomethionine) with four treatments and 13 replications of 10 birds each. Broiler breeders fed with organic Se had improved egg production in comparison to inorganic Se (p=0.038; p=0.044). Se concentration in whole egg and white egg were higher for organic Se in comparison to inorganic Se (p<0.001; p<0.001). The fertility and embryonic mortality were not significant between Se sources. No difference were observed to albumin height, Haugh unit and shell thickness for egg quality. The egg weight and yolk color were statistically different (p = 0.001; p = 0.026) for inorganic source compering to organic. The egg breaking was statistically better (p=0.007) for organic source. For progeny, no interactions between broiler diet and the maternal diet were observed for any of the criteria measured. No effect of maternal diet as well as broiler diet differences were observed on feed intake, body weight gain and carcass yield and cuts. However, feed conversion ratio was improved (p=0,017) in broiler from breeders fed selenomethione. Thus, selenomethionine has improved the egg production and quality, and has been transferred to the egg mainly in the egg white. Also, selenomethionine has improved feed conversion ratio because has a higher bioavailability.
APA, Harvard, Vancouver, ISO, and other styles
8

Gustafsson, Mattias. "Utvärdering av selenmetionins och nitroglycerins påväxthindrande effekter på havstulpaner för eventuell användning i båtbottenfärger : Evaluation of selenomethionine and nitro glycerine for possible use in boat paint to prevent barnacle fouling." Thesis, Linköping University, The Department of Physics, Chemistry and Biology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3963.

Full text
Abstract:

Påväxt på båtar och andra föremål som sätts ner i vattnet är ett stort och kostsamt problem världen över. I Sverige orsakar havstulpanen, Balanus improvisius, den största påväxten. Havstulpanen har många förstadier innan den blir en vuxen havstulpan. I det stadiet innan den sätter sig fast på olika platser, kallas den cyprid. Det tar mellan tre dagar och upp till några veckor innan cypriden valt plats att settla på. Den väljer plats mycket noggrant då den skall tillbringa resterade delen av sitt liv på denna.

Mycket forskning läggs ner på att finna ett alternativ till dagens giftiga båtbottenfärger. Tennorganiska föreningar, som använts för att motverka settling på båtbottnar, blir totalförbjudet 1 januari, 2008. Nu mer tillsätts allt oftare kopparföreningar istället vilket inte är någon större förbättring för miljön. Det finns idag många miljövänliga färger, som t.ex. silikonbaserad färg, men de fungerar inte lika bra som färgerna med metaller. Det forskas även på om ytan på båtbotten skall kunna förändras mekaniskt, för att motverka havstulpanens settling.

De substanser som är testade i denna rapport är selenmetionin och nitroglycerin. De testades i olika koncentrationsintervaller och i olika blandningar med varandra. Med en förhoppning om att selenmetioninen binder in i föreningar och då att hastigheten för reaktioner med tioler kan minska drastiskt och leda till gifteffekter, och att nitroglycerinen skall pacificera cypriden genom att binda till hemoglobinet istället för syre, skall dessa två substanser hålla cypriderna borta från båtbottnarna. Med föraningar om att substanserna har en synergistisk effekt då de blandas, skall lägre koncentrationer kunna användas. Då för höga koncentrationer är kostsamt och har troligen större negativ påverkan på miljön.

Selenmetionin visade en antydan till att minska settling men nitroglycerinen hade en mer främjande effekt på cypridens settling. Det visade sig även att substanserna hade en synergistisk effekt och därmed kan koncentrationerna för substanserna sänkas.


Biological growth on boats and other objects that are placed in water is a big and expensive problem over the entire world. In Sweden, the barnacle, Balanus improvisius, grows the most easily. This barnacle has many larvae stages before it becomes mature. During the larvae stage when it searching for a surface to settle on it is called cyprid. It takes between three days and a couple of weeks before a cyprid chooses a spot to settle on. It chooses the spot to settle on very carefully because it will spend the rest of its life on that exact place.

A lot of research goes into to finding a good alternative to today’s toxic boat paints. Tin organic compounds, as used to counteract settling of cyprids on boats, will be totally forbidden in January, 2008. As a replacement, copper compounds are being added more often to paints. These are not much better for the environment. Today there are many environmentally friendly paints, as for example silicon-based paint, but they do not work as well as the paints with metals. Research is also looking at mechanically changing a boat’s surface so that barnacles cannot attach as easily.

The substances that are tested in this report are selenomethionine and nitro glycerine. They were tested in different concentration intervals and in different mixes with each other with the hope of that selenomethionine will bound into compounds and then the reaction velocity with thioles will be reduced and give toxic effects. The nitro glycerine will make the barnacle passive through the idea that the NO is binding into a heme group instead of oxygen. It was hoped that the substances show a synergistic effect when they are mixed, allowing lower concentrations to be used. With too high concentrations in the paint, the paint becomes too expensive and likely has a bigger negative influence on the environment.

Selenomethionine showed an indication to reduce the likelihood that barnacles would settle on a pained surface, but nitro glycerine, on the other hand, caused an increased rate of cyprid settling. It was also shown that the substances had a synergistic effect and thus the concentrations for the substances can be lowered.

APA, Harvard, Vancouver, ISO, and other styles
9

Jonaitytė, Viktorija. "Skirtingų vitamino E kiekių, naudojant selenitą ir selenometioniną, įtaka viščiukų broilerių produktyvumui, virškinimo procesams bei paukštienos kokybei." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140618_232258-05733.

Full text
Abstract:
Tyrimų problema: vitaminas E ir selenas yra plačiai naudojami maisto papildai gerinant žmonių sveikatingumą. Tarpusavyje šie elementai pasižymi stipriu sinergetiniu veikimu. Vitamino E ir seleno transferacijos laipsnis iš lesalų į paukštieną yra sąlygojamas daugelio faktorių, kaip seleno ir vitamino E formų bei kiekių, sąveikos su kitais mikroelementais bei organinėmis rūgštimis, fitobiotikais, sintetiniais antioksidantais, lesalų gamybos technologinių procesų, paukščių auginimo sąlygų, jų imuniteto ir kt.. Todėl magistrinio darbo tikslas yra ištirti skirtingų vitamino E kiekių, naudojant selenitą ir selenometioniną, įtaką viščiukų broilerių produktyvumui, fiziologinei būklei bei paukštienos kokybei. Uždaviniai: 1.Nustatyti skirtingo vitamino E ir skirtingų koncentracijų seleno bei seleno formų įtaką viščiukų broilerių augimo intensyvumui, lesalų konversijai bei išsaugojimui. 2.Nustatyti skirtingo vitamino E ir skirtingų koncentracijų seleno bei seleno formų įtaką viščiukų broilerių fiziologinei būklei. 3.Nustatyti skirtingo vitamino E ir skirtingų koncentracijų seleno bei seleno formų įtaką viščiukų broilerių mėsos kokybei. Svarbiausios išvados: 1.Naudojant organinį seleną 0,3 mg/kg ir vitaminą E 70 mg/kg tiriamųjų viščiukų broilerių masė padidėjo 5,2% (p<0,05), lesalų konversija pagerėjo 5,2% ir viščiukų išsaugojimas padidėjo 4% palyginus su kontroline grupe. 2.Analizuojant tiriamosios grupės viščiukų broilerių kraujo rodiklius nustatėme, kad esminių skirtumų tarp... [toliau žr. visą tekstą]
The issue of investigation: vitamin E and selenium transferacion degree of feed to poultry is caused by many factors such as selenium and vitamin E forms and levels of interaction with other microelements, organic acids, phytobiotics, synthetic antioxidants, feed manufacturing processes, chicken broilers growing conditions, their immunity, etc.. Therefore, the aim of the Master is to investigate the different levels of vitamin E, using selenite and selenomethionine, on chicken broilers productivity, physiological condition and poultry quality. The tasks of the work: 1. To determine different vitamin E and selenium concentrations and different forms of selenium influence for chicken broilers growth rate, feed conversion and surviving. 2. To determine different vitamin E and selenium concentrations and different forms of selenium influence for chicken broilers physiological conditions. 3. To determine different vitamin E and selenium concentrations and different forms of selenium influence for chicken broilers meat quality. The most important conclusions: 1. When organic selenium 0.3 mg/kg and vitamin E 70 mg/kg was used, the weight of experimental broiler group increased 5.2% (p <0.05), feed conversion improved 5.2%, chicken surviving increased 4% in comparison with the control group. 2. The analysis of the blood parameters in a experimental group of chicken broilers showed that there wasn’t any substantial differences in cholesterol, HDL and LDL. However, the experimental... [to full text]
APA, Harvard, Vancouver, ISO, and other styles
10

Frisk, Peter. "Expressions of mercury-selenium interaction in vitro." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-4913-1/.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Selenomethionin"

1

Mead, Simon. Compartmental modelling of selinium as selenomethionine in the human body. 1995.

Find full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Selenomethionin"

1

Larsson, Anna M., and T. Alwyn Jones. "Selenomethionine Labeling of Recombinant Proteins." In Methods in Molecular Biology, 165–74. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-456-8_12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Grübler, G., H. Zimmermann, S. Stoeva, K. Pfeiffer, K. Baldes, and W. Voelter. "Ion-exchange chromatographic determination of selenomethionine." In Peptides 1994, 410–11. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-1468-4_184.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Spallholz, Julian E. "Selenomethionine and Methioninase: Selenium Free Radical Anticancer Activity." In Methods in Molecular Biology, 199–210. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-8796-2_15.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Wei, Guor-Jien, and Chi-Tang Ho. "Volatile Compounds Formed in a Glucose-Selenomethionine Model System." In ACS Symposium Series, 281–93. Washington, DC: American Chemical Society, 2002. http://dx.doi.org/10.1021/bk-2002-0826.ch018.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Butler, Judy A., and Philip D. Whanger. "Influence of Dietary Methionine on Selenomethionine Metabolism in Rats." In Trace Elements in Man and Animals 6, 337–38. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0723-5_109.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Wolffram, S., B. Berger, and E. Scharrer. "Transport of Selenomethionine and Methionine Across the Intestinal Brush Border Membrane." In Selenium in Biology and Medicine, 109–13. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74421-1_21.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Doublié, Sylvie. "Production of Selenomethionyl Proteins in Prokaryotic and Eukaryotic Expression Systems." In Methods in Molecular Biology, 91–108. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-209-0_5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Naumov, Alexander D., Natalia I. Timokhina, Alexandra V. Litvinchuk, Gennadii G. Vereshchako, Alina M. Khodosovskaya, Svetlana N. Sushko, and Elena M. Kadukova. "Radioprotective Properties of Selenomethionine with Methionine, Extracts from Basidium Fungi and Exogenous DNA." In NATO Science for Peace and Security Series A: Chemistry and Biology, 55–69. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-6513-9_5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Grønbæk, H., and O. Thorlacius-Ussing. "SELENIUM IN THE ANTERIOR PITUITARY AFTER A SINGLE INJECTION OF 75-SE L-SELENOMETHIONINE." In Selenium in Medicine and Biology, edited by Jean Nève and Alain Favier, 75–78. Berlin, Boston: De Gruyter, 1988. http://dx.doi.org/10.1515/9783110861990-014.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Oernsrud, R., and M. Lorentzen. "Bioavailability of Selenium from Untreated and Processed Selenomethionine-Enriched Fillets of Atlantic Salmon (Salmosalar)." In Trace Elements in Man and Animals 10, 891. New York, NY: Springer US, 2002. http://dx.doi.org/10.1007/0-306-47466-2_279.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Selenomethionin"

1

Juniper, D. T., C. Rymer, M. Briens, M. De Marco, J. Barbi, and G. Fontinhas. "Hydroxy-selenomethionine is an effective selenium source for pregnant heifers and their calf." In 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition. The Netherlands: Wageningen Academic Publishers, 2019. http://dx.doi.org/10.3920/978-90-8686-891-9_38.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Rahman, Md Mujibur, Jee Young Kwon, and Young Rok Seo. "Abstract 4861: Identification of novel potential targets for selenomethionine-mediated chemoprevention in colorectal carcinoma mouse model via proteomics analysis." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4861.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Kaag, Matt G., John P. Richie, Arun Das, Ana Calcagnotto, Raghu Sinha, Wanda Neidig, Jiangang Liao, et al. "Abstract 3244: Supplementation with selenium-enriched yeast but not selenomethionine reduces oxidative stress in healthy men in a randomized clinical trial." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3244.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Ozten, Nur, Michael J. Schlicht, and Maarten C. Bosland. "Abstract 5579: Selenomethionine does not protect against testosterone plus 17 beta-estradiol-induced prostate carcinogenesis and prostatic oxidative stress in NBL rats." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-5579.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Jung, Hwa Jin, Ju Han Lee, Seok Won Jeong, Jee Young Kwon, Jee Yeon Park, Hye Lim Kim, Young Ju Lee, Sung-Goo Chang, and Young Rok Seo. "Abstract A40: The enhancement of p53 stability via the inhibition of JNK-modulated ubiquitination with the activation of redox factor 1 (Ref-1) in response to non-genotoxic antioxidant selenomethionine (semet)." In Abstracts: Frontiers in Cancer Prevention Research 2008. American Association for Cancer Research, 2008. http://dx.doi.org/10.1158/1940-6207.prev-08-a40.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Selenomethionin' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography