Academic literature on the topic 'Self-Microemulsifying Drug Delivery System'

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Journal articles on the topic "Self-Microemulsifying Drug Delivery System"

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Wang, Lingzhi, Wenrui Yan, Yurun Tian, Huanhuan Xue, Jiankai Tang, and Liwei Zhang. "Self-Microemulsifying Drug Delivery System of Phillygenin: Formulation Development, Characterization and Pharmacokinetic Evaluation." Pharmaceutics 12, no. 2 (2020): 130. http://dx.doi.org/10.3390/pharmaceutics12020130.

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Phillygenin, as an active ingredient of Forsythia suspensa, possesses a wide range of biological and pharmacological activity. However, its development and application are restricted due to its poor bioavailability and low solubility. Our work aimed to develop a self-microemulsifying drug delivery system to improve the oral bioavailability of phillygenin. The composition of the self-microemulsifying drug delivery system was preliminary screened by the pseudo-ternary phase diagram. Subsequently, the central composite design method was employed to optimize the prescription of the self-microemuls
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Wankhade, Vikrant P., Nivedita S. Kale, and K. K. Tapar. "Self Microemulsifying Nutraceutical and Drug Delivery Systems." International Journal of Pharmaceutical Sciences and Nanotechnology 7, no. 3 (2014): 2520–28. http://dx.doi.org/10.37285/ijpsn.2014.7.3.3.

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Many chemical entities and nutraceuticals are poor water soluble and show high lipophilicity. It’s difficult to formulate them into oral formulation because of its low aqueous solubility which ultimately affects bioavailability. To enhance the bioavailability of such drugs compounds, self microemulsifying drug delivery system is the reliable drug delivery system. In this system the drug is incorporated in the isotropic system and formulated as unit dosage form. Self microemulsifying drug delivery system is the novel emulsified system composed of anhydrous isotropic mixture of oils, surfactant,
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Aggarwal, Geeta, SasidharanLeelakumari Harikumar, Parul Jaiswal, and Kashmir Singh. "Development of self-microemulsifying drug delivery system and solid-self-microemulsifying drug delivery system of telmisartan." International Journal of Pharmaceutical Investigation 4, no. 4 (2014): 195. http://dx.doi.org/10.4103/2230-973x.143123.

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Meghana, Raykar, and Shinde Ramesh. "SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM: A LIPID BASED DRUG DELIVERY SYSTEM." INTERNATIONAL JOURNAL OF CURRENT RESEARCH AND INNOVATIONS IN PHARMA SCIENCES 1, no. 1 (2022): 16–21. https://doi.org/10.5281/zenodo.8017592.

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., Bhupinder Kaur, and Monika Sharma . "Self-Microemulsifying Drug Delivery System- A Recent Approach in Drug Delivery System." Journal of Current Pharma Research 8, no. 4 (2018): 2504–13. http://dx.doi.org/10.33786/jcpr.2018.v08i04.003.

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Deshmukh, Ashish, and Shirishkumar Kulkarni. "Solid self-microemulsifying drug delivery system of ritonavir." Drug Development and Industrial Pharmacy 40, no. 4 (2013): 477–87. http://dx.doi.org/10.3109/03639045.2013.768632.

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Josef, Elinor, and Havazelet Bianco-Peled. "Sponges carrying self-microemulsifying drug delivery systems." International Journal of Pharmaceutics 458, no. 1 (2013): 208–17. http://dx.doi.org/10.1016/j.ijpharm.2013.09.024.

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Choi, Sung-Up, Mi Jeong Kim, Sung Tae Kim, et al. "Development of Self-Microemulsifying Drug Delivery Systems of Poorly Water-Soluble Pazopanib for Improvement of Oral Absorption." Science of Advanced Materials 12, no. 1 (2020): 152–60. http://dx.doi.org/10.1166/sam.2020.3649.

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Self-microemulsifying drug delivery systems represent a stable formulation for enhancing the solubility and absorption efficacy of poorly soluble drugs. In this study, a self-microemulsifying drug delivery system (SMEDDS) was designed and applied for oral administration of poorly water-soluble pazopanib, a Biopharmaceutical Classification Class II anticancer drug. The solubility of pazopanib was first evaluated using various oils, surfactants, and co-surfactants. Pseudoternary phase diagrams were plotted to identify the selfemulsifying region and the phase behavior of optimized vehicle selecte
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Al-Tamimi, Duaa J., and Ahmed A. Hussien. "Formulation and Characterization of Self-Microemulsifying Drug Delivery System of Tacrolimus." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 30, no. 1 (2021): 91–100. http://dx.doi.org/10.31351/vol30iss1pp91-100.

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 The present investigation aimed to formulate a liquid self-microemulsifying drug delivery system (SMEDDS) of tacrolimus to enhance its oral bioavailability by improving its dispersibility and dissolution rate. Four liquid SMEDDS were prepared using maisine CC as oil phase, labrasol ALF as surfactant and transcutol HP as co-surfactant based on the solubility studies of tacrolimus in these components. The phase behavior of the components and the area of microemulsion were evaluated using pseudoternary phase diagrams. The formulations were also assessed for thermodynamic stability,
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Zhang, Yuxia, Yan Bai, Huali Chen, Yuanrui Huang, Pei Yuan, and Liangke Zhang. "Preparation of a colon-specific sustained-release capsule with curcumin-loaded SMEDDS alginate beads." RSC Advances 7, no. 36 (2017): 22280–85. http://dx.doi.org/10.1039/c6ra27693h.

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Dissertations / Theses on the topic "Self-Microemulsifying Drug Delivery System"

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Challis, Deborah. "Physicochemical and biopharmaceutical studies of novel self-emulsifying systems for administration by the oral route (SEDDS)." Thesis, University of Bath, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280871.

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Whitmire, Rachel Elisabeth. "Self-assembling polymeric nanoparticles for enhanced intra-articular anti-inflammatory protein delivery." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/43587.

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The goal of this thesis was to develop a new drug-delivering material to deliver anti-inflammatory protein for treating OA. Our central hypothesis for this work is that a controlled release/presentation system will more effectively deliver anti-inflammatory protein therapies to the OA joint. The primary goal of this work was to synthesize a block copolymer that could self-assemble into injectable, sub-micron-scale particles and would allow an anti-inflammatory protein, IL-1ra, to be tethered to its surface for efficient protein delivery. The block copolymer incorporated an oligo-ethylene mono
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Uesaka, Akihiro. "Precise Structural and Functional Control of Molecular Assemblies Composed of Amphiphilic Peptides Having a Hydrophobic Helical Block." 京都大学 (Kyoto University), 2015. http://hdl.handle.net/2433/199273.

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Miranda, Beatriz Nogueira Messias de. "Mucus-penetrating polymersomes as a potential lung drug delivery system: preparation, in vitro characterization, and biodistribution tests." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/75/75135/tde-14032019-095025/.

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O muco protege o corpo humano de partículas externas, mas também representa uma barreira para a entrega de controlada de medicamentos através de nanocarregadores. Para ultrapassar a barreira do muco e impedir mucoadesão, nanopartículas sólidas são normalmente revestidas com polímeros inertes, tais como o polietileno glicol (PEG). No entanto, trata-se de um procedimento relativamente complexa. Nesta tese, estudamos métodos para fabricar nanocarreadores com uma excepcional combinação de propriedades, incluindo uma boa capacidade de mucopenetração e uma grande capacidade de carga. Ao contrário do
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Zhao, Tianjing. "Self-nanoemulsifying drug delivery systems (SNEDDS) for the oral delivery of lipophilic drugs." Doctoral thesis, University of Trento, 2015. http://eprints-phd.biblio.unitn.it/1608/1/Doctoral_thesis-Self-nanoemulsifying_drug_delivery_systems_(SNEDDS)_for_the_oral_delivery_of_lipophilic_drugs-Tianjing_ZHAO.pdf.

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The increasing number of lipophilic drug candidates in development in the pharmaceutical industry calls for advanced drug delivery systems with increased bioavailability less day-to-day and food-intake-dependent. Many of these drug candidates possess poor water solubility, so that their dissolution rate in the gastrointestinal tract (GIT) limits their absorption following oral administration. In the past few decades, various lipid-based formulations have been investigated to enhance the bioavailability of such challenging drug candidates and to increase their clinical efficacy when administer
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Zhao, Tianjing. "Self-nanoemulsifying drug delivery systems (SNEDDS) for the oral delivery of lipophilic drugs." Doctoral thesis, Università degli studi di Trento, 2015. https://hdl.handle.net/11572/369035.

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The increasing number of lipophilic drug candidates in development in the pharmaceutical industry calls for advanced drug delivery systems with increased bioavailability less day-to-day and food-intake-dependent. Many of these drug candidates possess poor water solubility, so that their dissolution rate in the gastrointestinal tract (GIT) limits their absorption following oral administration. In the past few decades, various lipid-based formulations have been investigated to enhance the bioavailability of such challenging drug candidates and to increase their clinical efficacy when administere
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Fatnassi, Mohamed. "Microsphères nano-structurées obtenues par atomisation-séchage : synthèses, caractérisation, encapsulation et libération de principes actifs." Thesis, Montpellier 2, 2010. http://www.theses.fr/2010MON20243/document.

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L'objectif de cette thèse consiste à développer une approche globale couplant les procédés sol-gel, les propriétés d'auto-assemblage des tensioactifs et l'atomisation séchage afin d'encapsuler directement des principes actifs dans des microsphères nanostructurées. Nous nous attachons en particulier à étudier les variations de la localisation et l'état physique des principes actifs en fonction des paramètres de synthèse. Le but de ce travail est également de mettre en relation les propriétés de libération avec la texture et la composition des microsphères. En parallèle, cette thèse a aussi pour
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Wang, Han. "Developing Novel Drug Delivery Systems For Platinum-based Anticancer Drugs Using Coordination-driven Self-assembly." Kent State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=kent1595260147978142.

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Michaelsen, Maria Høtoft. "The effect of digestion and drug load on absorption of poorly water soluble drugs from self-nanoemulsifying drug delivery systems (SNEDDS)." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/59178.

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Aldosari, Basmah Nasser Abdullah. "Development and evaluation of self-nanoemulsifying drug delivery systems for oral delivery of indomethacin." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10044225/.

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In this study, indomethacin-loaded self-nanoemulsifying drug delivery systems (SNEDDS) were developed in liquid, solid and carrier-mediated formulations in order to improve the solubility of this model poorly water soluble drug. Liquid SNEDDS based on CapryolTM 90 (oil phase), Cremophor® RH 40 (surfactant) and Transcutol® HP (co-surfactant) were thermodynamically stable and produced clear nanoemulsions upon dilution. Optimized liquid formulations were transformed into solid SNEDDS by adsorption onto the inert carriers Syloid® XDP 3150, Neusilin® US2 and Florite® PS-200. Ratios of adsorbent: li
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Books on the topic "Self-Microemulsifying Drug Delivery System"

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Singh, Sachin Kumar, Samir Mehndiratta, Keshav Raj Paudel, Gabriele De Rubis, Harish Dureja, and Kamal Dua. Application of Self-Nanoemulsifying Drug Delivery Systems in Inflammatory Diseases. CRC Press, 2025. https://doi.org/10.1201/9781032697475.

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V, Kabanov Alexander, Felgner Philip L. 1950-, and Seymour L. W, eds. Self-assembling complexes for gene delivery: From laboratory to clinical trial. Wiley, 1998.

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Shelake, Priyanka, Vidya Nalawade, and Priyanka Majalekar. Solid self-emulsifying drug delivery system: Formulation & evaluation of solid self-emulsifying drug delivery BCS class II drug Mirtazipine. LAP Lambert Academic Publishing, 2020.

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Chandrakant, Mahajan Kiran. Formulation and Optimization of Self Emulsifying Drug Delivery System for Effective Anthelmintic Therapy. Quadry, Fatima, 2023.

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Pulsed and self-regulated drug delivery. CRC Press, 1990.

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Wadhwa, Jyoti. Self Emulsifying Drug Delivery Systems: A Formulation Approach for Poorly Soluble Drugs. LAP Lambert Academic Publishing, 2011.

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Mateescu, M. A., P. Ispas-Szabo, and E. Assaad. Controlled Drug Delivery: The Role of Self-Assembling Multi-Task Excipients. Woodhead Publishing, 2018.

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Mateescu, M. A., P. Ispas-Szabo, and E. Assaad. Controlled Drug Delivery: The Role of Self-Assembling Multi-Task Excipients. Woodhead Publishing, 2015.

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Kaushik, Deepak, and Ravinder Verma. Comprehensive Text Book on Self-Emulsifying Drug Delivery Systems. Bentham Science Publishers, 2021.

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Ravinder, Deepak Kaushik;. Comprehensive Text Book on Self-Emulsifying Drug Delivery Systems. Bentham Science Publishers, 2021.

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Book chapters on the topic "Self-Microemulsifying Drug Delivery System"

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Sailor, Girish U. "Self-Nanoemulsifying Drug Delivery Systems (SNEDDS): An Innovative Approach to Improve Oral Bioavailability." In Nanocarriers: Drug Delivery System. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4497-6_10.

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Holowka, Eric P., and Sujata K. Bhatia. "Self-Microemulsifying Materials." In Drug Delivery. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1998-7_4.

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Chalikwar, Shailesh S., Pankaj V. Dangre, Poorva P. Dusad, and Sanjay J. Surana. "Self-Emulsifying Drug Delivery System for Potential Nutraceuticals: Solidification Techniques and Quality by Design (QbD)." In Nutraceutical Delivery Systems. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003189671-12.

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Polshettiwar, Satish, Pankaj Khuspe, Vishnu Chaudhari, and Ashwin Kuchekar. "Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) in Central Nervous System Diseases." In Application of Self-Nanoemulsifying Drug Delivery Systems in Inflammatory Diseases. CRC Press, 2025. https://doi.org/10.1201/9781032697475-9.

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Dangre, Pankaj V., and Shailesh S. Chalikwar. "Self-Nanoemulsifying Drug Delivery System: Formulation Development and Quality Attributes." In Carbon Nanotubes and Nanoparticles. Apple Academic Press, 2019. http://dx.doi.org/10.1201/9780429463877-13.

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Ahmad, Javed, Saima Amin, Sanjeev Singh, Gulam Mustafa, and Md Abul Barkat. "Self-Nanoemulsifying Drug Delivery System for Improving Efficacy of Bioactive Phytochemicals." In Nanophytomedicine. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4909-0_5.

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Khang, Gil Son, Jae Chan Yang, Jong Tae Ko, et al. "Preparation and Characterization of Ibuprofen Using Self-Emulsifying Drug Delivery System In Vivo." In Advanced Biomaterials VII. Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-436-7.541.

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Katsumi, Hidemasa, Ying-Shu Quan, Fumio Kamiyama, and Akira Yamamoto. "Related Topic: Development of a Transdermal Drug Delivery System Using Self-Dissolving Microneedle Arrays Fabricated with Hyaluronic Acid." In Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Springer Japan, 2017. http://dx.doi.org/10.1007/978-4-431-56526-0_23.

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Sofiana, Annisa, and Rizki Fajar Utami. "The Potential of Black Cumin SNEDDS (Self-nanoemulsifying Drug Delivery System) on Total Cholesterol Level of Hypercholesterolemic Model Zebrafish (Danio Rerio)." In Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-048-0_38.

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Vishwas, Sukriti, Rubiya Khursheed, Sheetu Wadhwa, et al. "Mechanisms of Drug Delivery in Self-Nanoemulsifying Drug Delivery Systems." In Application of Self-Nanoemulsifying Drug Delivery Systems in Inflammatory Diseases. CRC Press, 2025. https://doi.org/10.1201/9781032697475-5.

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Conference papers on the topic "Self-Microemulsifying Drug Delivery System"

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Venkatesh, S., R. Preethi, B. Revathi, R. Dhanya, and B. Sachuthananthan. "A Review on Human Respiratory Model Development for Drug Delivery." In 2024 2nd International Conference on Self Sustainable Artificial Intelligence Systems (ICSSAS). IEEE, 2024. http://dx.doi.org/10.1109/icssas64001.2024.10760678.

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Du, Zhiyuan, Qingda Xu, Ye Xi, et al. "An Implantable Nanoelectrode for Simultaneous in-Situ Self-Referencing, Drug Delivery, and Reliable Fixed-Point Recording Within a Single Neuron." In 2025 IEEE 38th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2025. https://doi.org/10.1109/mems61431.2025.10917494.

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Grifoni, L., G. De Donno, G. Vanti, M. C. Bergonzi, C. Luceri, and A. R. Bilia. "Short Lecture “Cannabidiol loaded self-microemulsifying drug delivery systems (SMEDDS) for oral administration”." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1758961.

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Johnson, William D., Miguel Muzzio, Thomas L. Horn, Michael A. Zeligs, Elizabeth R. Glaze, and David L. McCormick. "Abstract 4931: Enhanced oral bioavailability of 3,3'-diindolylmethane administered in a self-microemulsifying drug delivery system (SMEDDS)." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-4931.

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Desai, Preshita, Arvind Thakkar, Jeffrey Wang, and Sunil Prabhu. "Abstract 2238: Self-microemulsifying drug delivery systems (SMEDDS) containing novel compounds for the chemoprevention of pancreatic cancer." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2238.

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Prabhu, Sunil, Preshita Desai, Naga Jyothi Thumma, and Jeffrey Wang. "Abstract 2165: Self-microemulsifying drug delivery systems (SMEDDS) containing novel compounds in combination with gemcitabine: Bioavailability enhancement and synergistic anticancer efficacy studies for pancreatic cancer management." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-2165.

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Prabhu, Sunil, Preshita Desai, Naga Jyothi Thumma, and Jeffrey Wang. "Abstract 2165: Self-microemulsifying drug delivery systems (SMEDDS) containing novel compounds in combination with gemcitabine: Bioavailability enhancement and synergistic anticancer efficacy studies for pancreatic cancer management." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-2165.

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Syukri, Yandi, Renny Nadya Oktari, Siti Zahliyatul Munawiroh, and Bambang Hernawan Nugroho. "Optimization and preparation of Self-Nanoemulsifying Drug Delivery System (SNEDDS) loaded glimepiride." In 3RD INTERNATIONAL CONFERENCE ON CHEMISTRY, CHEMICAL PROCESS AND ENGINEERING (IC3PE). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0062642.

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Ermawati, Dian Eka, Roro Karina Pambudi, Vinda Aviwiandari, et al. "Developing formula of SNEDDS (self nano emulsifying drug delivery system) antihypertensive herbals “Hortus Medicus”." In THE 14TH JOINT CONFERENCE ON CHEMISTRY 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0005630.

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Li, Yuanpei, Kai Xiao, Juntao Luo, Wenwu Xiao, Joyce Lee, and Kit S. Lam. "Abstract 4439: A reversibly self-crosslinking nano-carrier system for efficient anticancer drug delivery." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4439.

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Reports on the topic "Self-Microemulsifying Drug Delivery System"

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Chakraborty, Payel, and Tamilvanan Shunmugaperumal. Simvastatin repurposing towards endometriosis management: The use of self -nanoemulsifying drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2304p6131285.

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