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Journal articles on the topic 'Semi-solid dosage forms'

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1

Prathamesh, Regade* Nikita Patil Komal Bhusare Sardar Shelke Nilesh Chougule. "Evalution Tests Of Different Dosage Forms An Overview." International Journal of Pharmaceutical Sciences 2, no. 7 (2024): 673–87. https://doi.org/10.5281/zenodo.12721342.

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The pharmaceutical industry continually strives to develop and enhance drug delivery systems to meet the diverse needs of patients. This study undertakes a comprehensive evaluation of solid, liquid, and semisolid dosage forms commonly used in pharmaceutical formulations. The research encompasses a range of parameters, including physicochemical properties, stability, bioavailability, and patient acceptability, to provide a holistic view of these formulations. For Solid pharmaceutical formulations, like tablets and capsules, we explore factors impacting dissolution rates, disintegration, The imp
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Pandey, Shubham, Sujeet Pratap Singh, and Dr Tarkeshwar P. Shukla. "Review–Formulation Development of Semi-Solid Dosage Form." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 07, no. 09 (2023): 1–11. http://dx.doi.org/10.55041/ijsrem25878.

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Semi-solid dosage forms are generally found in medicines for all types of patients. Though, they have specific advantages, along with fast efficacy due to the devoid of dissolution time and quick absorption in the skin surface. Semi-solid formulations have been broadly used in pharmacy due to their high dosing adjustability, easy use off, and rapid onset of action. Keywords: Semi-solid dosage forms, Gels, Ointment, Cream
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Krishna Sailaja, A. "Study of Natural Excipients in Semi-Solid Dosage Forms." Journal of Clinical Case Reports and Studies 6, no. 2 (2025): 01–07. https://doi.org/10.31579/2690-8808/245.

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A significant proportion of pharmaceutical dosage forms are semi solid preparations. They serve as carriers for drugs that are topically delivered by way of the skin, cornea, rectal tissue, nasal mucosa, vagina, buccal tissue, urethral membrane, and external ear lining. This data collection's goal is to give readers a comprehensive understanding of the different tools, tactics, crucial process variables, and production and validation procedures processes specific to semisolid dosage forms.
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4

YAMAUCHI, Hitoshi. "Semi-solid Dosage Forms and Transdermal Drug Delivery System." Oleoscience 17, no. 11 (2017): 559–65. http://dx.doi.org/10.5650/oleoscience.17.559.

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5

Kanfer, Isadore, Seeprarani Rath, Potiwa Purazi, and Nyengeterai Amanda Mudyahoto. "In Vitro Release Testing of Semi-Solid Dosage Forms." Dissolution Technologies 24, no. 3 (2017): 52–60. http://dx.doi.org/10.14227/dt240317p52.

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6

Mariia, Velia, Ruban Olena, Khalavka Maryna, and Hohlova Larisa. "Research of the choice of the basis of a semi-solid medicine with a semi-solid extract of Feverfew (Tanacetum parthenium)." ScienceRise: Pharmaceutical Science, no. 1(29) (February 27, 2021): 51–59. https://doi.org/10.15587/2519-4852.2021.225764.

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<strong>The aim.</strong>&nbsp;To conduct the research on the choice of the basis for a mild drug with a semi-solid extract of feverfew for use in dermatology. <strong>Materials and methods.</strong>&nbsp;In the study of the solubility of a semi-solid extract of feverfew (SSFE) used the method of optical microscopy using a laboratory microscope &ldquo;Konus Academy&rdquo;. Determination of pH and homogeneity of the studied samples was performed according to the methods described in SPhU, Vol.1. The bioavailability of the model samples was investigated by diffusion in 3 % agar gel. Colloidal st
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7

Sahu, Yogesh, Arvind Singh Jadon, Prateek Jain, Bhupendra Singh Thakur, Basant Khare, and Anushree Jain. "An Overview on Recent Advances in Pharmaceutical Suspensions." International Journal of Medical Sciences and Pharma Research 7, no. 1 (2021): 1–3. http://dx.doi.org/10.22270/ijmspr.v7i1.54.

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The suspension is a biphasic liquid or semi-solid dosage form where the finely divided insoluble solid drug particles are homogeneously dispersed in a liquid or semi-solid medium. The solid drug particles act here as the dispersed phase and the liquid or the semi-solid as the dispersion medium. The particle diameter in a suspension is usually greater than 0.5 µm. However, it is difficult and also impractical to impose a sharp boundary between the suspensions and the dispersions having finer particles. Suspensions are an important class of pharmaceutical dosage forms. The advantages of suspensi
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8

Schwarz, E., and S. Pfeffer. "Use of subambient DSC for liquid and semi solid dosage forms." Journal of Thermal Analysis 48, no. 3 (1997): 557–67. http://dx.doi.org/10.1007/bf01979502.

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9

Haverkamp, Jan Boris, Uwe Lipke, Thomas Zapf, Rudolf Galensa, and Cornelia Lipperheide. "Contamination of semi-solid dosage forms by leachables from aluminium tubes." European Journal of Pharmaceutics and Biopharmaceutics 70, no. 3 (2008): 921–28. http://dx.doi.org/10.1016/j.ejpb.2008.06.012.

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10

Svіtlana, Bilous, and Kovalevskaya Inna. "Study of the stability of organoleptic and structural-mechanical indicators of semi-solid preparations with metal nanoparticles." ScienceRise: Pharmaceutical Science, no. 1(17) (February 28, 2019): 39–44. https://doi.org/10.15587/2519-4852.2019.158590.

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<strong>Aim.</strong>&nbsp;Research of the stability of organoleptic and rheological properties of semi-solid preparations with silver and gold nanoparticles. <strong>Methods.</strong>&nbsp;For the study of organoleptic parameters, a classic method for determining the stability with periodic control of dosage forms in two temperature regimens was used: 8-15 &deg;C (cool place) and 15-25 &deg;C (room temperature). To study the rheological characteristics of semi-solid preparations, a rotary viscometer with a system of coaxial cylinders was used. <strong>Results.</strong>&nbsp;We studied three m
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11

Brown, Teagan, Steve Petrovski, Hiu Chan, Michael Angove, and Joseph Tucci. "Semi-Solid and Solid Dosage Forms for the Delivery of Phage Therapy to Epithelia." Pharmaceuticals 11, no. 1 (2018): 26. http://dx.doi.org/10.3390/ph11010026.

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12

Nardi-Ricart, Anna, Maria Jose Linares, Faviola Villca-Pozo, et al. "A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)." PLOS ONE 13, no. 9 (2018): e0201643. http://dx.doi.org/10.1371/journal.pone.0201643.

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13

Gennari, Chiara G. M., Francesca Selmin, Paola Minghetti, and Francesco Cilurzo. "Medicated Foams and Film Forming Dosage Forms as Tools to Improve the Thermodynamic Activity of Drugs to be Administered Through the Skin." Current Drug Delivery 16, no. 5 (2019): 461–71. http://dx.doi.org/10.2174/1567201816666190118124439.

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Medicated foams and film forming systems are dosage forms formulated to undergo a controlled metamorphosis when applied on the skin. Indeed, due to the presence of propellant or a particular air-spray foam pump, a liquid can generate foam when applied on the stratum corneum, or a liquid or conventional dosage form can form on the skin a continuous film as a consequence of the solvent evaporation. Thanks to these controlled modifications, the drug thermodynamic activity increases favoring the skin penetration and, therefore, the bioavailability with respect to conventional semi-solid and liquid
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14

Herbig, Michael E., Dirk-Heinrich Evers, Sascha Gorissen, and Melanie Köllmer. "Rational Design of Topical Semi-Solid Dosage Forms-How Far Are We?" Pharmaceutics 15, no. 7 (2023): 1822. http://dx.doi.org/10.3390/pharmaceutics15071822.

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Specific aspects of semi-solid dosage forms for topical application include the nature of the barrier to be overcome, aspects of susceptibility to physical and chemical instability, and a greater influence of sensory perception. Advances in understanding the driving forces of skin penetration as well as the design principles and inner structure of formulations, provide a good basis for the more rational design of such dosage forms, which still often follow more traditional design approaches. This review analyses the opportunities and constraints of rational formulation design approaches in the
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15

Pooja, Kumari, Dilip Agrawal Dr., Ashok Kumar Sharma Mr., Mohit Khandelwal Mr., Shaneza Aman Ms., and Shweta bhandari Ms. "AN RECENT ADVANCEMENT IN TOPICAL DOSAGE FORMS: A REVIEW." International Journal of Current Pharmaceutical Review and Research 13, no. 1 (2021): 01–08. https://doi.org/10.5281/zenodo.12667307.

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There are many semisolid dosage forms but creams, pastes, emulsions, ointments, gels, andrigid foams etc are main examples of this category of dosage form. They serve as carriers fordrugs that are topically, administered by route of the skin (derma), retina, rectal tissue, nasalmucosa, vagina, buccal tissue, urethral membrane, and external ear lining. Extant definitionsof lotions, gels, creams and ointments vary depending on literature source, market history ortraditional use. This often leads to confusion when deciding which topical Dosages forms toprescribe and purchase. The purpose of this
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16

Shah, Nidhi, Anuja Rana, Shuchi Mitra, Usha Sharma, and Khem Chand Sharma. "A Comprehensive Exploration of Topical Dosage Form in Ayurveda: A Review." Scholars International Journal of Traditional and Complementary Medicine 7, no. 02 (2024): 19–25. http://dx.doi.org/10.36348/sijtcm.2024.v07i02.001.

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In order to effectively deliver drug molecules to their intended targets in the body, different dosage forms are utilized. Adapting dosage forms to the specific needs of the modern era and the condition of the disease can enhance the provision of healthcare to those in need, particularly through the use of herbal and traditional (Unani and Ayurvedic) products. Ayurveda employs various classifications of dosage forms, such as Aushadha kalpana and Ahara kalpana. Aushadha kalpana can be further categorized into Primary kalpana (Panchavidha kashaya Kalpana) and Secondary kalpana. These classificat
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17

Stamate, Monica Cretan, Carmen Gafitanu, Ciprian Stamate, and Eliza Gafitanu. "Evaluation of Surface Roughness Variations of Solid Dosage Forms in Simulated Physiological Conditions." Applied Mechanics and Materials 245 (December 2012): 68–73. http://dx.doi.org/10.4028/www.scientific.net/amm.245.68.

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Rehabilitation of joints that underwent major surgery, involves reducing postoperative pain and inflammation. Many pharmaceutical product used in reducing joint pain are based on the extended-release technology and becoming increasingly important in research domain. The performance of extended-release matrix tablets is dependent on the solid dosage properties like matrix materials used, which are semi-synthetic polymer like hydroxypropyl methylcellulose (HPMC) and sodium carboxy methylcellulose (Na CMC). Depending on the properties of the polymer used, drug release from the tablets may be cont
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18

Chattaraj, S. C., J. Swarbrick, and I. Kanfer. "A simple diffusion cell to monitor drug release from semi-solid dosage forms." International Journal of Pharmaceutics 120, no. 1 (1995): 119–24. http://dx.doi.org/10.1016/0378-5173(94)00426-6.

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19

Santosh Kumar, Rada, and Annu Kumari. "Superdisintegrant: crucial elements for mouth dissolving tablets." Journal of Drug Delivery and Therapeutics 9, no. 2 (2019): 461–68. http://dx.doi.org/10.22270/jddt.v9i2.2480.

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Mouth dissolving tablets have gained more popularity among solid oral dosage forms. They perform better than conventional tablets because of its ease of administration and patient’s compliance. It facilitates water less administration and rapid onset of action. It also helps in improving oral bioavailability. The fast disintegration followed by dissolution leads to quick therapeutic activity makes these tablets superior over available tablets and capsules. Disintegration is an important key step for any solid dosage forms to show its pharmacologic effect as any solid dosage forms should disper
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20

Sjöholm, Erica, Rathna Mathiyalagan, Xiaoju Wang, and Niklas Sandler. "Compounding Tailored Veterinary Chewable Tablets Close to the Point-of-Care by Means of 3D Printing." Pharmaceutics 14, no. 7 (2022): 1339. http://dx.doi.org/10.3390/pharmaceutics14071339.

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Certain patient populations receive insufficient medicinal treatment due to a lack of commercially available products. The number of approved veterinary products is limited, making animals a patient population with suboptimal medicinal treatments available. To answer to this unmet need, compounding and off-label use of human-marketed products are practiced. Both of which have a significant risk of preparation errors. Hence, there is a dire demand to find and implement a more automated approach to the accurate, precise, and rapid production of veterinary dosage forms close to the point-of-care.
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21

Suárez-González, Javier, Eduardo Díaz-Torres, Cecilia N. Monzón-Rodríguez, Ana Santoveña-Estévez, and José B. Fariña. "Revolutionizing Three-Dimensional Printing: Enhancing Quality Assurance and Point-of-Care Integration through Instrumentation." Pharmaceutics 16, no. 3 (2024): 408. http://dx.doi.org/10.3390/pharmaceutics16030408.

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Three-dimensional printing in the field of additive manufacturing shows potential for customized medicines and solving gaps in paediatric formulations. Despite successful clinical trials, 3D printing use in pharmaceutical point-of-care is limited by regulatory loopholes and a lack of Pharmacopoeia guidelines to ensure quality. Semi-solid extrusion is a 3D printing technology that stands out for its versatility, but understanding the fluid dynamics of the semi-solid mass is critical. The aim of this research is to look into the advantages of instrumenting a 3D printer with a semi-solid extrusio
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22

Raman, Subashini, Vikneswaran Murugaiyah, and Thaigarajan Parumasivam. "Andrographis paniculata Dosage Forms and Advances in Nanoparticulate Delivery Systems: An Overview." Molecules 27, no. 19 (2022): 6164. http://dx.doi.org/10.3390/molecules27196164.

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Andrographis paniculata is a well-known Asian medicinal plant with a major phytoconstituent of diterpene lactones, such as andrographolide, 14-deoxyandrographolide, and neoandrographolide. A World Health Organization (WHO) monograph on selected medicinal plants showed that A. paniculata extracts and its major diterpene lactones have promising anti-inflammatory, antidiabetic, antimalarial, anticancer, antifungal, antibacterial, antioxidant, and hypoglycemic activities. However, these active phytochemicals have poor water solubility and bioavailability when delivered in a conventional dosage for
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23

Salamanca, Constain, Alvaro Barrera-Ocampo, Juan Lasso, Nathalia Camacho, and Cristhian Yarce. "Franz Diffusion Cell Approach for Pre-Formulation Characterisation of Ketoprofen Semi-Solid Dosage Forms." Pharmaceutics 10, no. 3 (2018): 148. http://dx.doi.org/10.3390/pharmaceutics10030148.

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This study aimed to evaluate and compare, using the methodology of Franz diffusion cells, the ketoprofen (KTP) releasing profiles of two formulations: A gel and a conventional suspension. The second aim was to show that this methodology might be easily applied for the development of semi-solid prototypes and claim proof in pre-formulation stages. Drug release analysis was carried out under physiological conditions (pH: 5.6 to 7.4; ionic strength 0.15 M; at 37 °C) for 24 h. Three independent vertical Franz cells were used with a nominal volume of the acceptor compartment of 125 mL and a diffusi
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24

Hashizaki, Kaname, Yuto Hoshii, Kosuke Ikeuchi, et al. "A Method for Measuring the Surface Free Energy of Topical Semi-solid Dosage Forms." Chemical and Pharmaceutical Bulletin 69, no. 11 (2021): 1083–87. http://dx.doi.org/10.1248/cpb.c21-00537.

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25

Al-Rimawi, Fuad, and Mohammad Atieh. "Preparation of Semi-Solid Dosage Forms Containing Psidium Guava Leaves Extract as Antimicrobial Preservative." Jordan Journal of Pharmaceutical Sciences 16, no. 2 (2023): 460. http://dx.doi.org/10.35516/jjps.v16i2.1499.

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Guava leaves extract has several medicinal activities as antimicrobial, antioxidant, anti-cancer and anti-inflammatory. Several studies have been proposed to use guava leaves extract in several preparations. However, applying guava leaves extract as a preservative in a pharmaceutical product has not been studied previously. In the present work, Guava leaves extract was used as natural preservative instead of chemical ones (methyl and propyl paraben). Guava leaves were extracted with ethanol 95% as extraction solvent with a percentage yield of 20%. This extract was tested by HPLC; several pheno
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26

R, B. Saudagar, and A. Gangurde P. "Film Forming Gels: A Review." International Journal of Current Pharmaceutical Review and Research 9, no. 3 (2017): 244–48. https://doi.org/10.5281/zenodo.12674504.

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Film forming gels are a novel approach in this area that might present at an alternative to the conventional dosage formused on the skin , such as ointments , creams , gels or patches. The polymeric solution is applied to the skin as a liquid andforms an alomost invisible film in situ by solvent evaporation. transdermal drug delivery system and dermal drug deliverysystem can provide some desirable performance over conventional pharmaceutical dosage formulations, such as avoidinggut and hepatic first-pass metabolism, improving drug bioavailability, reducing dose frequency and stabilizing drugde
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R, B. Saudagar, and A. Gangurde P. "Film Forming Gels: A Review." International Journal of Current Pharmaceutical Review and Research 8, no. 3 (2017): 244–48. https://doi.org/10.5281/zenodo.12677529.

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Film forming gels are a novel approach in this area that might present at an alternative to the conventional dosage formused on the skin , such as ointments , creams , gels or patches. The polymeric solution is applied to the skin as a liquid andforms an alomost invisible film in situ by solvent evaporation. transdermal drug delivery system and dermal drug deliverysystem can provide some desirable performance over conventional pharmaceutical dosage formulations, such as avoidinggut and hepatic first-pass metabolism, improving drug bioavailability, reducing dose frequency and stabilizing drugde
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28

Aina, Morenikeji, Fabien Baillon, Romain Sescousse, et al. "Development of Personalised Immediate-Release Gel-Based Formulations Using Semi-Solid Extrusion." Gels 10, no. 10 (2024): 665. http://dx.doi.org/10.3390/gels10100665.

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Precision in dosing is crucial for optimizing therapeutic outcomes and preventing overdosing, especially in preterm infants. Traditional manual adjustments to adapt the dose often lead to inaccuracies, contamination risks, and reduced precision. To overcome these challenges, semi-solid extrusion 3D printing was used to create personalised gel-based caffeine dosage forms. The hydrogels, made from agar and hydroxypropyl methylcellulose, demonstrated excellent rheological properties, ensuring uniform extrusion and accurate shape retention during and after printing. This gel formulation allowed fo
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29

Bartos, Csilla, Piroska Szabó-Révész, Tamás Horváth, Patrícia Varga, and Rita Ambrus. "Comparison of Modern In Vitro Permeability Methods with the Aim of Investigation Nasal Dosage Forms." Pharmaceutics 13, no. 6 (2021): 846. http://dx.doi.org/10.3390/pharmaceutics13060846.

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Nowadays, the intranasal route has become a reliable alternative route for drug administration to the systemic circulation or central nervous system. However, there are no official in vitro diffusion and dissolution tests especially for the investigation of nasal formulations. Our main goal was to study and compare a well-known and a lesser-known in vitro permeability investigation method, in order to ascertain which was suitable for the determination of drug permeability through the nasal mucosa from different formulations. The vertical diffusion cell (Franz cell) was compared with the horizo
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Nurdin, Erpi Nurdin. "A Study of Fungal Growth in Alternative Media of Breadfruit (Artocarpus altilis) in Direct and Powder Formulations." Biocelebes 15, no. 1 (2021): 21–29. http://dx.doi.org/10.22487/bioceb.v15i1.15515.

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Background: Medium is a material consisting of a mixture of nutrients which functions as a place to grow microbes. Semi-synthetic media such as PDAs contain sufficient carbohydrates so that they are good for use for fungal growth. This medium is quite a lot needed in the breeding of Candida albicans and Aspergillus niger both in the laboratory. However, the price of this media is quite expensive and limited, while the need is increasing so that alternative media are needed to replace the breeding.&#x0D; Objective: To determine the growth rate of unicellular and multicellular fungi on breadfrui
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31

Sirisha, V., and P. Tripura Sundari. "Formulation and Evaluation of Semi Solid Dosage Forms Based On Naturally Occurring Analgesic Agent Camphor." American Journal of PharmTech Research 9, no. 6 (2019): 43–56. http://dx.doi.org/10.46624/ajptr.2019.v9.i6.003.

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32

Teżyk, Michał, Bartłomiej Milanowski, Andrzej Ernst, and Janina Lulek. "Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review." Drug Development and Industrial Pharmacy 42, no. 8 (2015): 1195–214. http://dx.doi.org/10.3109/03639045.2015.1122607.

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33

Sjöholm, Erica, Rathna Mathiyalagan, Dhayakumar Rajan Prakash, et al. "3D-Printed Veterinary Dosage Forms—A Comparative Study of Three Semi-Solid Extrusion 3D Printers." Pharmaceutics 12, no. 12 (2020): 1239. http://dx.doi.org/10.3390/pharmaceutics12121239.

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Currently, the number of approved veterinary medicines are limited, and human medications are used off-label. These approved human medications are of too high potencies for a cat or a small dog breed. Therefore, there is a dire demand for smaller doses of veterinary medicines. This study aims to investigate the use of three semi-solid extrusion 3D printers in a pharmacy or animal clinic setting for the extemporaneous manufacturing of prednisolone containing orodispersible films for veterinary use. Orodispersible films with adequate content uniformity and acceptance values as defined by the Eur
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34

Chattaraj, S. C., and I. Kanfer. "‘The insertion cell’: A novel approach to monitor drug release from semi-solid dosage forms." International Journal of Pharmaceutics 133, no. 1-2 (1996): 59–63. http://dx.doi.org/10.1016/0378-5173(95)04410-8.

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35

Białek, Antoni, Julia Krysztofiak, Aleksandra Hozakowska, et al. "Novel Soft Dosage Forms for Paediatric Applications: Can We 3D-Print Them or Not?" Gels 11, no. 3 (2025): 187. https://doi.org/10.3390/gels11030187.

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Over the past years, numerous novel dosage forms, including gels, have been investigated for paediatric treatment due to the need to provide flexible dose adjustment possibilities, as well as a patient-friendly approach to drug delivery. Simultaneously, 3D printing technology is continuously advancing and gaining interest as a tool for personalised formulation development. Multiple additive manufacturing methods, including the semi-solid extrusion, especially used in gel printing, provide flexibility regarding the dose of active ingredients and the adjustment of the design of soft dosage forms
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Kute, Vaibhav Ghansham, Rajeshwari Satish Patil, Vaishnavi Ghansham Kute, and Priti Dilip Kaluse. "Immediate-release dosage form; focus on disintegrants use as a promising excipient." Journal of Drug Delivery and Therapeutics 13, no. 9 (2023): 170–80. http://dx.doi.org/10.22270/jddt.v13i9.6217.

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Disintegrants are materials or mixtures of substances added in the drug formulations, which make easier dispersion or breakup of tablets and ingredients of capsules in small-scale particles for fast dissolution then it comes in contact with water in the GI tract. Immediate drug release dosage forms disintegrate rapidly after administration with an enhanced rate of dissolution. The superdisintegrants provide instantaneous disintegration of tablets after administration in the stomach. In this field, immediate-release liquid dosage forms and parenteral dosage forms have also been introduced for t
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Chattaraj, S. C., and I. Kanfer. "Release of acyclovir from semi-solid dosage forms: A semi-automated procedure using a simple plexiglass flow-through cell." International Journal of Pharmaceutics 125, no. 2 (1995): 215–22. http://dx.doi.org/10.1016/0378-5173(95)00126-4.

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38

Zuikina, Ye. V., M. V. Buryak, and S. S. Zuikina. "Study of rheological and texture properties of emulsion ointment bases using modern emulsifiers." Annals of Mechnikov Institute, no. 2 (June 16, 2023): 85–93. https://doi.org/10.5281/zenodo.8046319.

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<strong>Introduction.</strong> Dermatological diseases are not only a medical, but also a social problem, which significantly worsens the quality of life of people suffering from them. Emulsion-based ointments are the most adapted to human skin medicinal form in extemporaneous practice. They have high therapeutic efficiency and satisfactory consumer properties due to the presence of two phases at once, are able to provide improved diffusion of active pharmaceutical ingredients (API), maintain optimal concentration in the area of application, have high adhesive properties, which allows them to
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39

Serrano, Dolores R., Aytug Kara, Iván Yuste, et al. "3D Printing Technologies in Personalized Medicine, Nanomedicines, and Biopharmaceuticals." Pharmaceutics 15, no. 2 (2023): 313. http://dx.doi.org/10.3390/pharmaceutics15020313.

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3D printing technologies enable medicine customization adapted to patients’ needs. There are several 3D printing techniques available, but majority of dosage forms and medical devices are printed using nozzle-based extrusion, laser-writing systems, and powder binder jetting. 3D printing has been demonstrated for a broad range of applications in development and targeting solid, semi-solid, and locally applied or implanted medicines. 3D-printed solid dosage forms allow the combination of one or more drugs within the same solid dosage form to improve patient compliance, facilitate deglutition, ta
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40

Rodríguez-Pombo, Lucía, Atheer Awad, Abdul W. Basit, Carmen Alvarez-Lorenzo, and Alvaro Goyanes. "Innovations in Chewable Formulations: The Novelty and Applications of 3D Printing in Drug Product Design." Pharmaceutics 14, no. 8 (2022): 1732. http://dx.doi.org/10.3390/pharmaceutics14081732.

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Since their introduction, chewable dosage forms have gained traction due to their ability to facilitate swallowing, especially in paediatric, geriatric and dysphagia patients. Their benefits stretch beyond human use to also include veterinary applications, improving administration and palatability in different animal species. Despite their advantages, current chewable formulations do not account for individualised dosing and palatability preferences. In light of this, three-dimensional (3D) printing, and in particular the semi-solid extrusion technology, has been suggested as a novel manufactu
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Zuykina, E.V., and N. P. Polovko. "Justification of conditions of salicylic acid introduction into emulsion ointment base composition." Annals of Mechnikov Institute, no. 2 (June 8, 2020): 30–34. https://doi.org/10.5281/zenodo.3885073.

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<strong>Introduction.</strong> The revival of extemporaneous production requires the updating of prescriptions, the improvement of the technology of drugs, the study of stability in the process of storage in order to extend the shelf life. Semi-solid dosage forms, which take more than 25&nbsp;% of medicines prepared in pharmacies about the stock, are currently prepared on a vaseline base. It has many disadvantages compared to the modern emulsion bases that are widely used in European practice. Therefore, the creation and implementation of modern emulsion bases for semi-soled dosage forms is a
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42

Roman, Vaishnavi* Gaikwad Rutuja. "Development And Characterization of Lornoxicam Tablets Incorporating Banana Starch as A Superdisintegrating for Enhanced Dissolution." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 2058–63. https://doi.org/10.5281/zenodo.15232534.

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Orally disintegrating tablets (ODTs) are an emerging trend in novel drug delivery system and have received ever-increasing demand during the last few decades. ODTs are solid unit dosage forms, which disintegrate or dissolve rapidly in the mouth without chewing and water. This type of property in dosage form can be attained by addition of different excipients, in which disintegrants are the key adjuvant. In recent years, several newer agents have been developed known as super-disintegrants. Super-disintegrants are used to improve the efficacy of solid dosage form and influence the release rate
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43

Severino, Patrícia, Wanessa Santana, Erika S. Lisboa, et al. "Cutaneous/Mucocutaneous Leishmaniasis Treatment for Wound Healing: Classical versus New Treatment Approaches." Microbiology Research 13, no. 4 (2022): 836–52. http://dx.doi.org/10.3390/microbiolres13040059.

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Cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (ML) show clinical spectra that can range from a localized lesion (with a spontaneous healing process) to cases that progress to a generalized systemic disease with a risk of death. The treatment of leishmaniasis is complex since most of the available drugs show high toxicity. The development of an effective topical drug formulation for CL and ML treatment offers advantages as it will improve patient’s compliance to the therapy given the possibility for self-administration, as well as overcoming the first pass metabolism and the high
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44

Waszczuk, Mairique, Sara Elis Bianchi, Vanessa Pittol, et al. "The challenge of improving pterostilbene (PTS) solubility for solid and semi-solid dosage forms: The obtention of binary and ternary systems." International Journal of Pharmaceutics 635 (March 2023): 122736. http://dx.doi.org/10.1016/j.ijpharm.2023.122736.

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45

Dubashynskaya, Natallia, Valentina Petrova, and Yury Skorik. "Biopolymer Drug Delivery Systems for Oromucosal Application: Recent Trends in Pharmaceutical R & D." International Journal of Molecular Sciences 25, no. 10 (2024): 5359. http://dx.doi.org/10.3390/ijms25105359.

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Oromucosal drug delivery, both local and transmucosal (buccal), is an effective alternative to traditional oral and parenteral dosage forms because it increases drug bioavailability and reduces systemic drug toxicity. The oral mucosa has a good blood supply, which ensures that drug molecules enter the systemic circulation directly, avoiding drug metabolism during the first passage through the liver. At the same time, the mucosa has a number of barriers, including mucus, epithelium, enzymes, and immunocompetent cells, that are designed to prevent the entry of foreign substances into the body, w
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Блынская, E. Blynskaya, Турчинская, et al. "The Technology of Self-Emulsifying Drug Delivery Systems." Journal of New Medical Technologies 21, no. 1 (2014): 128–33. http://dx.doi.org/10.12737/3320.

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Nearly 40% of novel chemical entities show evidence of low solubility in water and low bioavailability. Self-emulsifying formulations have showed the power to improve the bioavailability of hydrophobic drugs. Self-emulsifying formulations belong to lipid formulations, and their size range from 100 nm in case of self-emulsifying drug delivery systems and less than 50 nm in case of self-microemulsifying drug delivery systems. In general self-emulsifying formulations s represent isotropic mixtures of oils, surfactants and co-surfactants, which emulsify spontaneous in aqueous media under condition
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Dhiman, Jasmine, Dhruv Dev, and D. N. Prasad. "Superdisintegrants: Brief Review." Journal of Drug Delivery and Therapeutics 12, no. 1 (2022): 170–75. http://dx.doi.org/10.22270/jddt.v12i1.5155.

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Oral disintegrating tablets are a new trend in novel drug delivery systems that have seen a surge in popularity in recent decades. To improve the efficacy of solid dosage forms, super disintegrants are used. This is accomplished by reducing the disintegration time, which improves the rate of drug dissolution. Disintegrants are substances or combination of substances added to a drug formulation to aid in the breaking up or disintegration of tablet or capsule content into smaller fragments that dissolve more quickly than without them. Several newer agents known as ‘Superdisintegrants’ have been
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48

Jha, Shubhendra, and Sheo Datta Maurya. "ORGANOGELS AS A POTENTIAL TOPICAL DRUG DELIVERY SYSTEM." International Journal of Drug Regulatory Affairs 1, no. 2 (2018): 49–58. http://dx.doi.org/10.22270/ijdra.v1i2.110.

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Semisolid preparations for external application to skin have gained much demand, since it is easily absorbed through the skin layers. Many novel topical dosage forms have been discovered, among which organogels appears to play an important role. Interest in organogels has increased in a wide variety of fields including chemistry, biotechnology and pharmaceutics. Organogels are thermodynamically stable, biocompatible, isotropic gel, which not only give localized effect, but also systemic effect through percutaneous absorption. Organogels are semi-solid systems, in which an organic liquid phase
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Sonar, Shivani, Sheetal Gondkar, and Ravindranath B. Saudagar. "Liquid Filled Hard Gelatin Capsule." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 832–35. http://dx.doi.org/10.22270/jddt.v9i3-s.2794.

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Novel dosage forms emerges more and more in recent years. One of them is liquid-filled hard gelatin capsules, which have gelatin or the hydroxypropyl methyl cellulose (HPMC) as capsule shell. The liquid-filled hard gelatin capsule is gradually getting attention because of its new-concept dosage form design, which bring liquid drugs by solid form. The paper mostly presents application, pharmaceutical manufacturing, quality assessment, vision of liquid-filled hard gelatin capsules and emphases on the application and pharmaceutical manufacturing of liquid-filled capsule. It is recommended that th
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ZUIKINA, YELIZAVETA. "THE IN VITRO RELEASE TESTING AND THE ANTIMICROBIAL ACTIVITY OF SEMI-SOLID DOSAGE FORMS WHICH CONTAIN SALICYLIC ACID." FARMACIA 69, no. 6 (2021): 1073–79. http://dx.doi.org/10.31925/farmacia.2021.6.8.

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