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Journal articles on the topic 'Semisolid Dosage Form'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

B, Yuvan, and Inniya C. "Nano Technology based Topical Semisolid Pharmaceutical dosage Forms." International Journal of Pharmacy and Biomedical Engineering 1, no. 1 (2014): 13–15. http://dx.doi.org/10.14445/23942576/ijpbe-v1i1p105.

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The pharmaceutical semisolid dosages are normally present in the form of paste, creams, gels, ointments. Generally these types of semisolid dosages are used only externally such as skin allergies, injuries, etc. The bases used in the semisolid pharmaceutical dosage are more sensitive to the skin. The topical semisolid medical dosages are spread smoothly on the body surface. It will react with the cells and injuries for long time because it adhered for long time. The main advantages of the semisolid dosage are it does not create side effects. This paper proposes the Nano technology based semiso

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Salve, Priyanka M., Shital V. Sonawane, Mayuri B. Patil, and Rajendra K. Surawase. "Dissolution and Dissolution Test Apparatus: A Review." Asian Journal of Research in Pharmaceutical Sciences 11, no. 3 (2021): 229–36. http://dx.doi.org/10.52711/2231-5659.2021.00037.

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Dissolution is an official test. These used by pharmacopeias for evaluating drug release of solid and semisolid dosages forms. The application of the dissolution testing ensures consistent product quality and to predict in vivo drug bioavailability. The dissolution test, in its simplest form, placing the formulation in a dissolution apparatus containing suitable dissolution medium, allowing it to dissolved specified period of time and then using appropriate rational method to determine the amount of drug. Dissolution test are probative and analysis like drug degradation profile, shelf-life stu

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Csóka, I., E. Bozsik, I. Erős, and T. L. Paál. "Regulatory aspects of semisolid dosage form design." European Journal of Pharmaceutical Sciences 32, no. 1 (2007): S9. http://dx.doi.org/10.1016/j.ejps.2007.05.019.

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Prathamesh, Regade* Nikita Patil Komal Bhusare Sardar Shelke Nilesh Chougule. "Evalution Tests Of Different Dosage Forms An Overview." International Journal of Pharmaceutical Sciences 2, no. 7 (2024): 673–87. https://doi.org/10.5281/zenodo.12721342.

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The pharmaceutical industry continually strives to develop and enhance drug delivery systems to meet the diverse needs of patients. This study undertakes a comprehensive evaluation of solid, liquid, and semisolid dosage forms commonly used in pharmaceutical formulations. The research encompasses a range of parameters, including physicochemical properties, stability, bioavailability, and patient acceptability, to provide a holistic view of these formulations. For Solid pharmaceutical formulations, like tablets and capsules, we explore factors impacting dissolution rates, disintegration, The imp

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Patil, P. B., S. K. Datir, and R. B. Saudagar. "A Review on Topical Gels as Drug Delivery System." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 989–94. http://dx.doi.org/10.22270/jddt.v9i3-s.2930.

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The clinical evidence indicates that topical gel is a safe and most effective treatment option for use in the management of skin related disease and used for local action to reduce the side effects associated with other conventional dosage form. Topical drug delivery systems include a large variety of pharmaceutical dosage form like semisolids, liquid preparation, sprays and solid powders. Most widely used semisolid preparation for topical drug delivery includes gels, creams and ointments. A gel is a cross-linked polymer network swollen in a liquid medium. Its properties depend strongly on the

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Kaushal, Dev, and Nikita Upadhyaya. "REVIEW ON OINTMENT." International Journal of Pharmaceutical Sciences and Medicine 7, no. 10 (2022): 30–38. http://dx.doi.org/10.47760/ijpsm.2022.v07i10.003.

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Ointments are semisolid dosage form which usually act as visco-elastic materials when shear stress is applied. They generally contain medicinal ingredients and are used to be applied externally to the body for therapeutic effect. Many therapeutic agents used for topical application to intact or broken skin or to mucous membranes are presented in the form of semisolid consistency variously designated as ointments, creams, pastes etc. It is used mainly as protective or emollient for the skin. The first step towards the goal is screening of plants used in popular medicine. Along with other dosage

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SAKATA, Osamu, Hiraku ONISHI, and Yoshiharu MACHIDA. "Development of Semisolid Dosage Form of Clonazepam for Oral Cavity Administration." YAKUGAKU ZASSHI 130, no. 1 (2010): 119–25. http://dx.doi.org/10.1248/yakushi.130.119.

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Bhinde, SonamSagar, SagarMahendrabhai Bhinde, VirendrakumarK Kori, SwapnilY Chaudhari, BiswajyotiJ Patagiri, and KalpnaS Patel. "Pharmaceutical validation of modified Chitraka Haritaki Avaleha: An ayurveda semisolid dosage form." Journal of Indian System of Medicine 9, no. 1 (2021): 33. http://dx.doi.org/10.4103/jism.jism_109_20.

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9

van Amerongen, I. A., H. A. G. De Ronde, and N. T. M. Klooster. "Physical-chemical characterization of semisolid topical dosage form using a new dissolution system." International Journal of Pharmaceutics 86, no. 1 (1992): 9–15. http://dx.doi.org/10.1016/0378-5173(92)90025-w.

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Joshi, Shruti B., Dr Bharti Umretia, and Prof Dr Bharat D. Kalsariya. "Standard Manufacturing Procedure of Dadrughni Vati (Lepa) and Its Modified Dosage Form Dadrughna Malahara: Tradition to Innovation." International Journal of Pharmaceutical Research and Applications 10, no. 1 (2025): 996–1005. https://doi.org/10.35629/4494-10019961005.

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Introduction: Herbo-mineral formulations, require systematic pharmaceutical procedures to ensure efficacy, safety, and consistency. The increasing global demand for high-quality Ayurvedic products necessitates the development of Standard Manufacturing Procedures (SMPs). This study aims to design and establish an SMP for two Ayurvedic formulations, Dadrughni Vati (Lepa) and Dadrughna Malahara, ensuring reproducibility and quality across multiple batches. Materials and Methods: The study involved the procurement, identification, and preparation. The preparation of Dadrughni Vati (Lepa) involved

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Shivatare, Rakesh, Shailesh Kewatkar, Neetin Bhutale, Vibhavari Chatur, and Harshal Tare. "A Validated IVRT Method to Evaluate Semisolid Dosage Form Containing Ximenynic Acid Using a Novel Approach." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 306–15. http://dx.doi.org/10.25258/ijddt.14.1.44.

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Purpose: Ximenynic acid (XMA) holds significant potential in the market, especially due to its widespread application in the cosmetics sector. As its various biological activities continue to be discovered, there is a sharp rise in demand for ximenynic acid. A novel analytical approach has been devised for an in-house product, comparable to the reference listed drug (Softalia, containing 30% ximenynic acid), utilized in gel formulations. This method is designed to conduct in-vitro release studies employing Franz vertical diffusion cell apparatus and analytical quantification via high-performan

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Luc, V. V., Y. L. Kolicheva, V. V. Gladishev, and A. P. Lisyanska. "Basis of optimal concentration of active pharmaceutical ingredients in combdrugs for external use with antimycotic activity." Farmatsevtychnyi zhurnal, no. 3-4 (August 14, 2018): 53–59. http://dx.doi.org/10.32352/0367-3057.3-4.17.06.

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An analysis of the state of modern resources for pharmacotherapy of foot mycosis was carried out. It showed that the creation of semisolid dosage forms for the topical skin, foot web space and nail treatment with bioactive compound from the group of nonspecific antimycotic substances (2-mercaptobenztiazol, chinozol) on the base of domestic technology ia actual for the modern pharmaceutical and medical science. Successful realization this project will allow to propose the effective complaentic and available for the wide segment of the Ukrainian medications for the effective foot mycisis therapy

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Jain, Priyanshi, Ashish Gupta, and Gajanan Darwhekar. "An Detailed Overview on Mouth Dissolving Film." Journal of Drug Delivery and Therapeutics 13, no. 7 (2023): 172–76. http://dx.doi.org/10.22270/jddt.v13i7.6121.

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The present review aims to enlighten about a potential dosage form that is mouth dissolving films. Mouth dissolving film is a rapidly dissolving dosage form that dissolves in the mouth within a few seconds without the intake of water and is mainly used for pediatric and geriatric patients due to its flexibility and patient compliance. It is a potential dosage form for drugs having high metabolism and low bioavailability. Solvent casting, hot melt extrusion, solid dispersion, semisolid casting, rolling, and other processes can all be used to create mouth dissolving film, but solvent casting is

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OCHIUZ, Lacramioara, Andreea CRETEANU, Manuela HORTOLOMEI, et al. "Development study of new topical formulations with erythromycin." Romanian Journal of Pharmaceutical Practice 10, no. 3 (2017): 109–15. http://dx.doi.org/10.37897/rjphp.2017.3.1.

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Erythromycin is a macrolide antibiotic prescribed for the topical treatment of acne. Pharmacologically, erythromycin has the disadvantage of being poorly soluble in water. This leads to formulation challenges in semisolid dosage forms. In recent years, many published studies have shown the ability of cyclodextrins to form complexes with drugs. These new complexes are characterized by much improved solubility and permeation compared to the „parent“ molecule. The aim of this study was to synthesize an inclusion complex of erythromycin and lactide-β-cyclodextrin for the formulation of semisolid b

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Badyal, Sakshi, Poonam Dang, Puneet Dhawan, and Himanshu Shekhar Tiwari. "Ayurvedic Dosage Forms: Pressing Priorities and Challenges therein with Respect to Solid and Semisolid Oral Dosage Forms." Indian Journal of Ayurveda and Integrative Medicine KLEU 5, no. 2 (2024): 66–70. https://doi.org/10.4103/ijaim.ijaim_4_24.

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ABSTRACT Continuous improvements in elevating traditional dosage forms to increase therapeutic efficacy, to enable patient-centric approaches, and to improve patient compliance are becoming more rational with advancements in technology and an advanced vision to address the existing concerns. Oral dosage forms are well known and still the preferred choice of drug administration methods due to their convenience and cost-effectiveness. Hence, newer areas are explored to modify the preexisting traditional as well as present-day dosage forms to encounter the changing market needs. Search engines an

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Bhavadip, Tanna* Dhirendra Kumar Tarai Khyati Bhupta Dr. Santosh R. Kirtane. "Development And Validation of RP-HPLC Method for Estimation of Esmolol HCL from Semisolid Dosage Form." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2741–64. https://doi.org/10.5281/zenodo.15442329.

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Esmolol Hydrochloride belongs to the class II anti-arrhythmic drugs. Topical Esmolol Hydrochloride used as a Novel Treatment Modality for Diabetic Foot Ulcers. Development and validation of Simple, Precise and Accurate RP-HPLC method for estimation of Esmolol Hydrochloride in Semi solid dosage form. The validation of this method was achieved as per ICH Q2 (R2) guidelines with the optimized experimental conditions. To achieve the proposed method on Intsil C18 column (300 mm x 3.9 mm, 5 µm) column as Stationary Phase and run time was 20 min. The Mobile Phase consists of Acetonitrile:6.8g/L

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Omer Sid Ahmed, Murtada A. Oshi, and Lamia Abdalla Gadien. "Novel Tablet Dosage Forms to Improve the Oral Bioavailability of Curcumin: A Short Review." Omdurman Journal of Pharmaceutical Sciences 2, no. 2 (2022): 169–75. http://dx.doi.org/10.52981/ojps.v2i2.2205.

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AbstractCurcumin is a yellow pigment that is considered as the major biologically active compound of turmeric plant. Curcumin has antioxidant, anti-inflammatory, anti-microbial, anti-neoplastic, and anti-depressant properties. However, due to poor oral bioavailability, its applications has been largely hampered in the clinical settings. Currently, advances in curcumin formulations to different dosage forms such as tablets, capsules or semisolid preparations have been resulted in solving its poor oral bioavailability and subsequently increasing the blood levels of drug for therapeutic activity.

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Hladyshev, V. V., D. M. Romanina, O. B. Kharaponova, et al. "Comparative study of specific activity of the piroctone olamine semisolid dosage form for external use." Current issues in pharmacy and medicine: science and practice 15, no. 2 (2022): 168–73. http://dx.doi.org/10.14739/2409-2932.2022.2.258934.

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The external treatment of seborrheic dermatitis of the scalp depends on the withdrawal of clinical symptoms and the complaints the patient made to the doctor. At present Ukrainian dermatology has several dozen pharmacotherapeutic products in this direction, with dominating medicines of ketoconazole, zinc pyrition, and their combinations. They are characterized by the short-term or weak effect, associated with the pathogenic microorganisms’ resistance against the background of long-term use of biologically active substances which are their active parts. One way to solve the problem is using the

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Hajare, iss A. B., M. M. Nitalikar, C. S. Magdum, S. K. Mohite, S. J. Shid, and V. N. Dange. "Formulation and optimization of dermatological dosage form for comparative in-vitro evaluation of semisolid bases." Research Journal of Topical and Cosmetic Sciences 7, no. 2 (2016): 46. http://dx.doi.org/10.5958/2321-5844.2016.00008.x.

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Madur, Saili, Vinod Matole, Mallinath Kalshetti, Smeeta Patil, and Aishwarya Sakhare. "NEW VISIBLE SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION OF KETOCONAZOLE IN PURE AND SEMISOLID DOSAGE FORM." Asian Journal of Research in Chemistry and Pharmaceutical Sciences 08, no. 01 (2020): 7–11. http://dx.doi.org/10.36673/ajrcps.2020.v08.i01.a02.

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Gharat, KB Bokade AS Kasekar NM Kadam VJ. "Ayurveda: The Mystery of Life." British Journal of Pharmaceutical and Medical Research 04, no. 03 (2019): 1801–9. https://doi.org/10.24942/bjpmr.2019.475.

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Ayurveda is a life science which explains about the different dosage forms, which is the physical form of a medication intended for administration. the different dosage forms can be prepared by the physician according to his yukti, considering <em>samyoga, vishesha, kala </em>and<em> samskara</em>[1]. Ayurveda is the system of medicine that evolved in India with a rational logical foundation and it has survived as a distinct entity from remote antiquity to the present day. The fundamental on which ayurvedic system is based are essentially true for all times and do not change from are to age<su

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Soloviova, Alina, Halyna Kukhtenko, and Olha Kaliuzhnaia. "Substantiation of the composition of a semi-solid dosage form with a probiotic component for use in dermatology." EUREKA: Health Sciences, no. 6 (November 30, 2021): 54–63. https://doi.org/10.21303/2504-5679.2021.002181.

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One of the important issues in the pharmaceutical development of a semisolid preparation for dermal use is the scientific and experimental justification for choosing the base-carrier of active substances. The aim of this study was to experimentally substantiate the choice of rational combination of excipients in the development of a semisolid dosage form with a probiotic component for use in dermatology. Materials and methods. Hydrophilic gelling agents were used as excipients in the study: Sepiplus 400, Aristoflex AVC, Carbopol 934, hydroxyethylcellulose HEC, sodium alginate. Physical and che

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Jeedi, Amaresha, Srinivas Yadav, and Surekha S. Medikeri. "Pharmaceutico analytical study of Mukha Kanthikara Lepa and development of its new dosage form into Cream and Gel." Journal of Ayurveda and Integrated Medical Sciences (JAIMS) 5, no. 05 (2020): 158–66. http://dx.doi.org/10.21760/jaims.5.5.22.

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The need for cosmetics is seen from very ancient days; peoples were using variety of cosmetic products both for curative purpose as well as enhancing beauty. Mukhakantikara Lepa is a polyherbal formulation mentioned in Sharandhara Samhita in the form of Churna, which is extensively used to enhance skin complexion. In present time, the difficulty of portability, application, removal and shelf life of the Churna is a great challenge to Lepa form though being effective. Here arises a need for newer dosage form. Creams and gels are semisolid preparations which may be defined as topical products in

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Soloviova, Alina, Halyna Kukhtenko, and Olha Kaliuzhnaia. "Substantiation of the composition of a semi-solid dosage form with a probiotic component for use in dermatology." EUREKA: Health Sciences, no. 6 (November 30, 2021): 54–63. http://dx.doi.org/10.21303/2504-5679.2021.002181.

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One of the important issues in the pharmaceutical development of a semisolid preparation for dermal use is the scientific and experimental justification for choosing the base-carrier of active substances. The aim of this study was to experimentally substantiate the choice of rational combination of excipients in the development of a semisolid dosage form with a probiotic component for use in dermatology. Materials and methods. Hydrophilic gelling agents were used as excipients in the study: Sepiplus 400, Aristoflex AVC, Carbopol 934, hydroxyethylcellulose HEC, sodium alginate. Phys

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Chunda, Jaykumar R.1 Naik Shreya N.*2. "Formulation And Evaluation Of Soft Medicated Jellies For Treatment Of Vitamin B12 Deficiency." International Journal in Pharmaceutical Sciences 2, no. 9 (2024): 363–73. https://doi.org/10.5281/zenodo.13731662.

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An innovative kind of oral dosage is oral medicated jelly. There is a need to design such dose form in order to address challenges presented by juvenile and geriatric patients in administering standard dosage forms. It is especially good for people who have difficulty swallowing. Oral jelly may be readily chewed and dissolves in saliva without the need for water, giving it a unique form other than dose form. Patients are further drawn to its beauty and delicate texture, resulting in excellent patient acceptability. Jelly is a semisolid dosage form that is clear, non-greasy, and suitable for bo

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Pooja, Kumari, Dilip Agrawal Dr., Ashok Kumar Sharma Mr., Mohit Khandelwal Mr., Shaneza Aman Ms., and Shweta bhandari Ms. "AN RECENT ADVANCEMENT IN TOPICAL DOSAGE FORMS: A REVIEW." International Journal of Current Pharmaceutical Review and Research 13, no. 1 (2021): 01–08. https://doi.org/10.5281/zenodo.12667307.

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There are many semisolid dosage forms but creams, pastes, emulsions, ointments, gels, andrigid foams etc are main examples of this category of dosage form. They serve as carriers fordrugs that are topically, administered by route of the skin (derma), retina, rectal tissue, nasalmucosa, vagina, buccal tissue, urethral membrane, and external ear lining. Extant definitionsof lotions, gels, creams and ointments vary depending on literature source, market history ortraditional use. This often leads to confusion when deciding which topical Dosages forms toprescribe and purchase. The purpose of this

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Vrushali, S. Gangurde*1 Pradnya H. Kapse2 Khanderao Jadhav3 Rishikesh Bachhav4. "Mouth Dissolving Films: A novel approach in oral drug delivery." International Journal in Pharmaceutical Sciences 2, no. 4 (2024): 1223–36. https://doi.org/10.5281/zenodo.11080675.

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The most sophisticated oral solid dose forms are mouth dissolving or orodispersible films because of their versatility and ease of usage. The Mouth Dissolving film is a solid oral dosage form that, when placed in the mouth without water or chewing, dissolves and decomposes rapidly. By avoiding first pass metabolism, the drug's bioavailability is increased when taken in this dosage form. Additionally, orodispersible films may result in a lower dosage, a quicker onset of action, and no choking hazards. Solvent casting and semisolid casting methods are used to laminate API chemicals that mask fla

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Kopylova, A. I., T. A. Kobeleva, and A. I. Sichko. "The Use of the Method of Multiwave Spectrophotometry in Quality Control of Tizol Gel and Metronidazole in a New Mild Dosage Form «Metronidazole»." Medicina 12, no. 3 (2024): 45–54. http://dx.doi.org/10.29234/2308-9113-2024-12-3-45-54.

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Introduction. For the introduction of new medicines into medical practice, a mandatory stage is quality control, which includes determining the quantitative content of active components using modern methods of pharmaceutical analysis. Tizol gel, included in soft dosage forms, is an independent pharmacologically active agent, therefore it is important to evaluate its content in complex medicinal preparations. Aim. To develop a method for quantitative determination of tizol gel and metronidazole in a new semisolid dosage form «Metronidazole» using multiple-wavelength spectrophotometry. Materials

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Velya, M. I., O. A. Ruban, I. V. Kovalevska, M. V. Khalavka, and O. V. Gerush. "The substantiation of the composition of a soft medicine for the therapy of inflammatory diseases of the musculoskeletal system." News of Pharmacy 105, no. 1 (2023): 57–65. http://dx.doi.org/10.24959/nphj.23.110.

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Aim. To substantiate the optimal composition of the base of the semisolid dosage form with the thick extract of feverfew (Tanacetum parthebased on structural-mechanical, textural, adhesive and microscopic studies. Materials and methods. The study objects were samples of a semisolid dosage form with the thick extract of feverfew with various gelling agents and the reference drug “Irikar”. In the course of the research, a complex of structural-mechanical methods and the microscopic analysis of the samples were used. Results and discussion. The studies of structural-mechanical properties have det

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Matole, Vinod, Smita Kumbhar, Yogesh Thorat, et al. "METHOD DEVELOPMENT AND VALIDATION OF AMOROLFINE IN BULK AND ITS SEMISOLID DOSAGE FORM BY VISIBLE SPECTROPHOTOMETRY." Asian Journal of Research in Chemistry and Pharmaceutical Sciences 08, no. 01 (2020): 17–21. http://dx.doi.org/10.36673/ajrcps.2020.v08.i01.a04.

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Nagendra, R.1 Sheetal P.*2 Nanditha V. V.3 Venkatesh K.4 Hanumanthachar Joshi5. "Oral Disintegrating Film: A Review." International Journal in Pharmaceutical Sciences 2, no. 2 (2024): 206–16. https://doi.org/10.5281/zenodo.10640441.

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Oral disintegrating films (ODF) hold great promise for novel and inventive drug delivery methods. Because it is flexible and comfortable to use, mouth dissolving film is the most advanced oral solid dosage form available. Mouth dissolving films are oral solid dosage forms that, when placed in the mouth without water or chewing, dissolve and disintegrate within a minute. With this dosage form, the drug can avoid the first pass metabolism, potentially increasing its bioavailability. Mouth dissolving films have the ability to reduce dosage, improve the onset of action, and get rid of choking anxi

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Pawar, Rajat, Ravi Sharma, Pravin Sharma, and G. N. Darwhekar. "A Review on Mouth Dissolving Film." Journal of Drug Delivery and Therapeutics 9, no. 6 (2019): 206–10. http://dx.doi.org/10.22270/jddt.v9i6.3676.

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Mouth dissolving film is the most advanced oral solid dosage form due to its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of medication may be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films involves both the visual and performance characteristics as p

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Daharwal, Shrinoy, Rajat Pawar, and Sunita Sonartiya. "A REVIEW ON MOUTH DISSOLVING FILM." International Journal of Pharmaceutical Sciences and Medicine 7, no. 5 (2022): 48–59. http://dx.doi.org/10.47760/ijpsm.2022.v07i05.005.

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Oral route of Mouth dissolving film is the most advanced oral solid dosage form due which it is very much in use now a day because of it’s flexibility and comfort. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within few minutes when placed in tongue without taking water. This dosage form allows the medication to bypass the first pass metabolism, so that the bioavailability of medication can be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films inv

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Swati Saxena, Abhishek Patel, and Sarang Kumar Jain. "Formulation and evaluation of mouth dissolving film of antihypertensive agentFormulation and evaluation of mouth dissolving film of antihypertensive agent." World Journal of Advanced Research and Reviews 16, no. 2 (2022): 1107–16. http://dx.doi.org/10.30574/wjarr.2022.16.2.1251.

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Mouth dissolving film is the one of the most advanced oral solid dosage form because of its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of medication may be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films involves both the visual and performance chara

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Swati, Saxena, Patel Abhishek, and Kumar Jain Sarang. "Formulation and evaluation of mouth dissolving film of antihypertensive agentFormulation and evaluation of mouth dissolving film of antihypertensive agent." World Journal of Advanced Research and Reviews 16, no. 2 (2022): 1107–16. https://doi.org/10.5281/zenodo.7790668.

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Mouth dissolving film is the one of the most advanced oral solid dosage form because of its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of medication may be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films involves both the visual and performance chara

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Berenguer, Diana, Maria Magdalena Alcover, Marcella Sessa, et al. "Topical Amphotericin B Semisolid Dosage Form for Cutaneous Leishmaniasis: Physicochemical Characterization, Ex Vivo Skin Permeation and Biological Activity." Pharmaceutics 12, no. 2 (2020): 149. http://dx.doi.org/10.3390/pharmaceutics12020149.

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Amphotericin B (AmB) is a potent antifungal successfully used intravenously to treat visceral leishmaniasis but depending on the Leishmania infecting species, it is not always recommended against cutaneous leishmaniasis (CL). To address the need for alternative topical treatments of CL, the aim of this study was to elaborate and characterize an AmB gel. The physicochemical properties, stability, rheology and in vivo tolerance were assayed. Release and permeation studies were performed on nylon membranes and human skin, respectively. Toxicity was evaluated in macrophage and keratinocyte cell li

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Park, Hye Jin, and Dong Wuk Kim. "Customizable Self-Microemulsifying Rectal Suppositories by Semisolid Extrusion 3D Printing." Pharmaceutics 16, no. 11 (2024): 1359. http://dx.doi.org/10.3390/pharmaceutics16111359.

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Objectives: This study aims to create an innovative self-microemulsifying drug delivery system (SMEDDS) suppository for ibuprofen (IBU) using semisolid extrusion (SSE) three-dimensional (3D) printing technology. Methods: Based on solubility studies and the ability to form a transparent microemulsion upon dilution, a selected oil, surfactant, and co-surfactant were utilized to prepare SMEDDS-3DPS containing IBU. The optimal formulation consisted of 10% Triacetin, 80% Gelucire 48/16, and 10% Tetraethylene glycol. SSE 3D printing was employed to create three different-sized suppositories with var

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Devaraj, Sarathkumar, Amuthalakshmi Sivaperuman, and Nalini Calambur Nagarajan. "Rp-uplc method development and validation for simultaneous estimation of mometasone furoate and miconazole nitrate in semisolid dosage form." ACTA Pharmaceutica Sciencia 58, no. 3 (2020): 335. http://dx.doi.org/10.23893/1307-2080.aps.05819.

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Estefania, Kaban Vera, Jansen Silalahi, Sumaiyah Sumaiyah, and Denny Satria. "Formulation and Evaluation of Cream Turmeric Extract Preparations from Turmeric Rhizomes (Curcuma domestica Val.)." Indonesian Journal of Pharmaceutical and Clinical Research 5, no. 1 (2022): 01–09. http://dx.doi.org/10.32734/idjpcr.v5i1.6479.

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The use of plants as a method of herbal treatment is a step that is currently being developed by many researchers to produce effective and minimal side effects. Turmeric is one of the most widely used cooking spices by the people of Indonesia. The main ingredients possessed by turmeric include curcumin (77%), demethoxy (17%) and bisdemethoxy (3%). One of the pharmaceutical preparations with a topical delivery system is a cream preparation which is a semi-solid dosage form, containing one or more drug ingredients dissolved or dispersed in an appropriate base material. Turmeric can be formulated

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Soloviova, A.V., and O.S. Kaliuzhnaia. "Study of stability of semi-solid drug "Probioskin" for skin application in the process of storage." Annals of Mechnikov Institute, no. 4 (December 6, 2021): 85–90. https://doi.org/10.5281/zenodo.5761544.

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<strong>Introduction. Currently, there are no means for the treatment of dermatological diseases in the domestic pharmaceutical market with the simultaneous correction and maintenance of the skin microbiome. We have developed a combined preparation with a probiotic component for the treatment of dermatological diseases in the form of an emulsion under the conditional name "Probioskin" with anti-inflammatory, antimicrobial, regenerating, emollient action. The development of a new medicinal product requires a study of the stability of its samples during storage by assessing all the qua

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Jovičić-Bata, Jelena, Nemanja Todorović, Veljko Krstonošić, et al. "Liquid- and Semisolid-Filled Hard Gelatin Capsules Containing Alpha-Lipoic Acid as a Suitable Dosage Form for Compounding Medicines and Dietary Supplements." Pharmaceutics 16, no. 7 (2024): 892. http://dx.doi.org/10.3390/pharmaceutics16070892.

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Liquid-filled hard gelatin capsules may have pertinent advantages both for therapeutic effect and extemporaneous preparations of medicines. Alpha lipoic acid is a substance used in medicines and dietary supplements and there is a need for creating an appropriate formulation which would be suitable for each individual patient or consumer. Based on its biopharmaceutical and physical chemical characteristics, eight different capsule formulations were designed and characterized. Silicon dioxide was added to form a semisolid content and prevent leakage. The formulation filled with alpha lipoic acid

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Romanina, D. M., I. I. Berdey, V. V. Gladishev, and G. P. Lisyanska. "Study of influence of the surface-active substances concentration on releasing of praziquantel from the rectal suppository." Farmatsevtychnyi zhurnal, no. 6 (August 14, 2018): 66–70. http://dx.doi.org/10.32352/0367-3057.6.16.04.

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Acne dermatosis (rosacea, perioral dermatitis, seborrheic dermatitis etc.) are one of the most actual problem in dermatology. Praziquantel is an antiparasitic medication effective towards trematodes, cestodes. Investigations developed by domestic scientists revealed antidemodicosis activity of praziquantel. Use of semisolid dosage forms for rectal administration will allow to increase its efficacy and minimize the risks of adverse reactions. On the department of technology of medications Zaporizhzhia State Medical University research of development of praziquantel rectal dosage form for

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Soloviova, A. V., and O. S. Kaliuzhnaia. "Technological aspects of the “Probioskin” emulgel development." News of Pharmacy 103, no. 1 (2022): 73–78. http://dx.doi.org/10.24959/nphj.22.88.

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Aim. To develop a rational technology of a new semisolid preparation for skin application with a probiotic component in the form of an emulgel under the conditional name “Probioskin”. Materials and methods. When developing the technology the study objects were emulgel samples with selected substances – a lyophilized biomass of lactobacilli, dexpanthenol, lactic acid, and excipients – Aristoflex AVC gelling agent, propylene glycol, polysorbate-80, tocopherol, peach oil. To control the quality of the samples, the requirements of the monograph of the SPhU 2.4 on dosage forms “Semi-solid preparati

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De Caro, Viviana, Libero Italo Giannola, and Giulia Di Prima. "Solid and Semisolid Innovative Formulations Containing Miconazole-Loaded Solid Lipid Microparticles to Promote Drug Entrapment into the Buccal Mucosa." Pharmaceutics 13, no. 9 (2021): 1361. http://dx.doi.org/10.3390/pharmaceutics13091361.

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The currently available antifungal therapy for oral candidiasis (OC) has various limitations restricting its clinical use, such as short retention time, suboptimal drug concentration and low patients compliance. These issues could be overcome using micro or nanotechnology. In particular, solid lipid microparticles (SLMs) resulted as a particularly promising penetration enhancer carrier for lipophilic drugs, such as the antifungal miconazole (MCZ). Based on these considerations, cetyl decanoate (here synthesized without the use of metal catalysis) was employed together with 1-hexadecanol to pre

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Jadhav, Mr Vinayak Devidas. "Review on: Herbal Ointment." International Journal for Research in Applied Science and Engineering Technology 13, no. 4 (2025): 5637–42. https://doi.org/10.22214/ijraset.2025.69615.

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Various areas where modern medicine is available, but the majority of the peoples in developing countries utilizes plants or plant preparations in their regular health care, many plant species have been proved to to possess antioxidant, antibacterial, and anti-inflammatory effects.A semisolid dose form, ointments often behave as visco-elastic materials under shear stress. Typically, they are given externally to the body to produce a therapeutic effect and include medicinal components. Natural medicines are also made in the form of ointments, along with various dosage forms. Numerous medicinal

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Divya, Jain*1 Dr. Ranajit Shinde2 Shital Patil3 Krunal Mali4 Hemant Mali5. "Revolutionizing Drug Delivery: 3D Printing of Gastro-Retentive Tablets for Enhanced Therapeutic Efficacy." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1933–49. https://doi.org/10.5281/zenodo.15388189.

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The ability of some heart, gastrointestinal, and infection medications to be absorbed in the body has been shown to improve significantly when using gastro-retentive dosage forms (GRDF). Because of their limited absorption windows, pharmaceutical experts usually find it difficult to develop the bioavailability of these medications at a clinically effective dosage strength. Nevertheless, these medications have a brief biological half-life, and formulations with quick release don't deliver drug levels within the therapeutic range. In addition, the need for multiple doses of the existing formulat

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Kumar, Prince, and Madhu Verma. "Pharmaceutical Suspensions: An Updated Patent Review on Novel Suspending Agents and Recent Advancement." Recent Advances in Drug Delivery and Formulation 17, no. 3 (2023): 193–209. http://dx.doi.org/10.2174/0126673878246149231010085610.

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Abstract: A wide variety of dosage forms are used for the oral administration of drugs to humans and animals. Apart from solid dosage forms, it also includes liquid dosage forms, such as solutions, suspensions, and emulsions. The selection is based on the physiochemical attributes of the therapeutically active ingredient. Suspensions are classified as dispersed systems that are heterogeneous in nature and consist of two phases. One phase is the continuous phase, the dispersion medium, or the external phase, which is either liquid or semisolid; the other is a solid particle dispersed in the ext

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Kikwai, Loice, Daren Tran, Walter W. Hauck, Vinod P. Shah, and Erika S. Stippler. "Effect of Various Operational Parameters on Drug Release from a 1% Hydrocortisone Semisolid Dosage Form Using the Vertical Diffusion Cell Apparatus." Dissolution Technologies 19, no. 3 (2012): 6–13. http://dx.doi.org/10.14227/dt190312p6.

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Albiero, Mattia, Alice Fullin, Gianmarco Villano, et al. "Semisolid Wet Sol–Gel Silica/Hydroxypropyl Methyl Cellulose Formulation for Slow Release of Serpin B3 Promotes Wound Healing In Vivo." Pharmaceutics 14, no. 9 (2022): 1944. http://dx.doi.org/10.3390/pharmaceutics14091944.

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Foot ulcerations are a disabling complication of diabetes and no treatment is currently available based on disease mechanisms. The protein serpin B3 (SB3) was identified as a positive biomarker of successful diabetic wound healing; therefore, its exogenous administration may promote healing. The topical administration of SB3 is challenging due to its protein nature. Physical entrapment in wet sol–gel silica can stabilize the protein’s conformation and permit its sustained delivery. However, irreversible syneresis and poor viscoelastic properties hamper wet sol–gel silica application as a semis

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Kumar, Ravinder. "Pharmaceutical Study of Malhara Kalpna Composed of Aloe Barbadensis and Terminalia Belerica." International Research Journal of Ayurveda & Yoga 05, no. 07 (2022): 41–46. http://dx.doi.org/10.47223/irjay.2022.5707.

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The pharmaceutical branch of Ayurveda known as Bhaisajya Kalpana Vigyan deals with the preparation of herbal and herbo-mineral formulations. Numerous infectious diseases in humans are brought on by microorganisms, which are found everywhere in the soil, water, and air. These microorganisms include bacteria, viruses, fungus, and parasites. Our Acharyas have often mentioned Malaharayogasas a way to prevent issues like this. Malhar kalpanafalls under the category of Bahya kalpana(external application). Compared to the other formulations, Malharhas a longer shelf element of Malhar. The second is a

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