Academic literature on the topic 'Sendai'

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Journal articles on the topic "Sendai"

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NA, Nancy Pe. "Sendai." Perspectives in the Arts and Humanities Asia 10, no. 2 (October 29, 2021): 287–88. http://dx.doi.org/10.13185/paha2020.10212.

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SATO, Yutaka. "Welcome to Sendai!" JOURNAL OF THE JAPAN WELDING SOCIETY 88, no. 3 (2019): 155–56. http://dx.doi.org/10.2207/jjws.88.155.

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Sasaki, Mutsuro. "Sendai Mediatheque, Japan." Structural Engineering International 12, no. 3 (August 2002): 146–48. http://dx.doi.org/10.2749/101686602777965315.

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Shoji, Tetsuo, and Masumi Saka. "Welcome to Sendai." Proceedings of the Asian Pacific Conference on Fracture and Strength and International Conference on Advanced Technology in Experimental Mechanics 1.01.203 (2001): A1. http://dx.doi.org/10.1299/jsmeatemapcfs.1.01.203.0_a1.

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Shoji, Tetsuo, and Masumi Saka. "Welcome to Sendai." Proceedings of the Asian Pacific Conference on Fracture and Strength and International Conference on Advanced Technology in Experimental Mechanics 2.01.03 (2001): A1. http://dx.doi.org/10.1299/jsmeatemapcfs.2.01.03.0_a1.

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OKADA, Satoru, Kouichi IIBUCHI, and Yasuo NAGAI. "GAIJIN-YA OF SENDAI 1N SENDAI-HAN DURING EDO-ERA." Journal of Architecture and Planning (Transactions of AIJ) 65, no. 527 (2000): 233–40. http://dx.doi.org/10.3130/aija.65.233_1.

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Kure, Shuichi, Taichi Tebakari, and Mamoru Miyamoto. "Review of Recent Water-Related Disasters and Scientific Activities in Southeast Asia: Lessons Learned and Future Challenges for Disaster Risk Reduction." Journal of Disaster Research 11, no. 3 (June 1, 2016): 394–401. http://dx.doi.org/10.20965/jdr.2016.p0394.

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This article reports on the public forum conducted by the authors at the Third United Nations World Conference on Disaster Risk Reduction, held in Sendai City, Miyagi Prefecture, Japan, from March 14 to 18, 2015. The conference included case studies of recent water-related disasters in the Southeast Asia region, reviews of academic research, and a description of the current situation about measures for risk reduction. This article also clarifies the relationship between the various recommendations proposed in the public forum and the Sendai Framework for Disaster Risk Reduction 2015–2030 (the Sendai framework), in order to identify the efforts that are necessary for the implementation of the Sendai framework.
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Kast, W. M., C. J. Boog, B. O. Roep, A. C. Voordouw, and C. J. Melief. "Failure or success in the restoration of virus-specific cytotoxic T lymphocyte response defects by dendritic cells." Journal of Immunology 140, no. 9 (May 1, 1988): 3186–93. http://dx.doi.org/10.4049/jimmunol.140.9.3186.

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Abstract C57BL/6 (B6, H-2b) mice are CTL responders to both Sendai virus and Moloney leukemia virus. In the former response the H-2Kb class I MHC molecule is used as CTL restriction element, in the latter response the H-2Db molecule. B6 dendritic cells (DC) are superior in the presentation of Sendai virus Ag to CTL in comparison with B6 normal spleen cells. Con A blasts have even less capacity to present viral Ag than NSC, and LPS blasts show an intermediate capacity to present viral Ag. H-2Kb mutant bm1 mice do not generate a CTL response to Sendai virus, but respond to Moloney leukemia virus, as demonstrated by undetectable CTL precursors to Sendai virus and a normal CTL precursor frequency to Moloney virus. Compared to B6 mice, other H-2Kb mutant mice show decreased Sendai virus-specific CTL precursor frequencies in a hierarchy reflecting the response in bulk culture. The Sendai virus-specific CTL response defect of bm1 mice was not restored by highly potent Sendai virus-infected DC as APC for in vivo priming and/or in vitro restimulation. In mirror image to H-2Kb mutant bm1 mice, H-2Db mutant bm14 mice do not generate a CTL response to Moloney virus, but respond normally to Sendai virus. This specific CTL response defect was restored by syngeneic Moloney virus-infected DC for in vitro restimulation. This response was Kb restricted indicating that the Dbm14 molecule remained largely defective and that a dormant Kb repertoire was aroused after optimal Ag presentation by DC. In conclusion, DC very effectively present viral Ag to CTL. However, their capacity to restore MHC class I determined specific CTL response defects probably requires at least some ability of a particular MHC class I/virus combination to associate and thus form an immunogenic complex.
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HOFFMANN, MICHAEL M., HUBERT SCHARNAGL, ELEFTHERIA PANAGIOTOU, WERNER T. BANGHARD, HEINRICH WIELAND, and WINFRIED MÄRZ. "Diminished LDL Receptor and High Heparin Binding of Apolipoprotein E2 Sendai Associated with Lipoprotein Glomerulopathy." Journal of the American Society of Nephrology 12, no. 3 (March 2001): 524–30. http://dx.doi.org/10.1681/asn.v123524.

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Abstract. Variants of apolipoprotein E (apoE) have been linked to lipoprotein glomerulopathy, a new glomerular disease characterized by the deposition of lipoproteins in mesangial capillaries. One third of affected patients are heterozygous for apoE2 Sendai (Arg145 Pro). Variants of apoE can also produce type III hyperlipoproteinemia (HLP). Recessive type III HLP is caused by apoE2 (Arg158 Cys), a mutant with diminished low-density lipoprotein (LDL) receptor binding but halfnormal heparin binding. Dominant type III HLP is caused by mutations that markedly alter heparin binding but modestly reduce receptor binding. This study examined whether apoE2 Sendai (Arg145 Pro) was functionally different from type III HLP-producing apoE variants by expressing apoE3, apoE2 (Arg158 Cys), apoE1 (Arg146 Glu), a dominant apoE variant, and apoE2 Sendai (Arg145 Pro) in the baculovirus system. LDL receptor binding was studied using recombinant apoE complexed to phospholipid vesicles and to very lowdensity lipoprotein from a patient with familiar apoE deficiency. Compared with apoE3, receptor-binding activities of apoE2 (Arg158 Cys), apoE1 (Arg146 Glu), and apoE2 Sendai (Arg145 Pro) all were less than 5%. Heparin-binding activities were 53%, 23%, and 66%, respectively, of apoE3. The distribution of apoE2 Sendai among the major plasma lipoprotein fractions was similar to that of apoE3 and apoE2 (Arg158 Cys). ApoE2 Sendai (Arg145 Pro) represents the only known mutation within the heparin-binding domain of apoE (residues 142 through 147), revealing diminished receptor binding and almost normal heparin binding. These unique characteristics of apoE2 Sendai (Arg145 Pro) may relate to the development of lipoprotein glomerulopathy.
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Percy, D. H., D. C. Auger, and B. A. Croy. "Signs and Lesions of Experimental Sendai Virus Infection in Two Genetically Distinct Strains of SCID/Beige Mice." Veterinary Pathology 31, no. 1 (January 1994): 67–73. http://dx.doi.org/10.1177/030098589403100109.

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The pathogenesis of Sendai virus infection was studied in genetically immunodeficient mice of genotype scid/scid.bg/bg (SCID-beige) using C.B-17 SCID-beige mice, a BALB/c-related strain that expresses the same major histocompatibility complex as the Sendai virus-susceptible DBA/2 (H-24). Mice were inoculated intranasals with isolate 771076 of Sendai virus, then killed at 2-day intervals beginning on day 4 post-inoculation. Clinical signs were evident beginning at 8 to 10 days post-inoculation, and all animals remaining were killed in extremis by 14 to 17 days post-inoculation. Lesions in inoculated mice were confined to the respiratory tract. In the nasal passages, a nonresolving rhinitis, with epithelial hyperplasia/metaplasia occurred. Cranioventral bronchopneumonitis was characterized by marked hyperplasia and necrosis of epithelial cells lining airways and with leukocytic infiltration. At the alveolar level, there was marked hypertrophy and hyperplasia of type II pneumocytes, mobilization of alveolar macrophages, and obliteration of the normal architecture in severely affected areas. Viral antigen was evident beginning at 4 days post-inoculation and persisted in affected areas throughout the duration of the study. Because immunocompetent C57BL/6 mice are known to be genetically resistant to Sendai virus, the susceptibility of C57B/6 SCID-beige to Sendai virus was then compared to that of C.B-17 SCID-beige mice. In age-matched animals of the two strains, there was no evidence of natural resistance to Sendai virus infection in the immunodeficient C57BL/6 strain compared to the C.B-17 mice. These studies indicate that the genetic differences in susceptibility of two strains of immunocompetent mice to Sendai virus infection are eliminated by expression of the mutations scid and beige.
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Dissertations / Theses on the topic "Sendai"

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Tarbouriech, Nicolas. "Etudes structurales de la phosphoprotéine du virus de Sendai." Université Joseph Fourier (Grenoble), 2000. http://www.theses.fr/2000GRE10075.

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Ce travail de these a permis d'explorer la structure de la proteine p du virus de sendai. Cette proteine est le cofacteur de la polymerase qui permet sa fixation sur la matrice d'arn recouvert de la proteine n. Elle est donc un element indispensable a la synthese d'arn par le virus. L'analyse de la sequence primaire de cette proteine a permis la definition de domaines structuraux qui a ete renforcee par une etude par proteolyse limitee. Nous avons etudie la forme generale et la contribution de chacun des domaines a cette forme par chromatographie sur tamis moleculaire et diffusion de rayons x ou de neutrons aux petits angles. Celle-ci s'est revelee tres allongee. Ces domaines ont ete etudies plus en details par pontage chimique, ultra-centrifugation analytique et par un test de dilution de his-tag. Ces experiences ont montre que cette proteine forme des tetrameres tres stables. Une etude par cristallographie aux rayons x a alors ete entreprise sur le domaine de multimerisation. Les premiers cristaux obtenus se sont reveles macles par une macle rare qui a ete etudiee et comprise. Une nouvelle construction, legerement plus courte, nous a permis grace a un derive de mercure et a une experience de dispersion anomale multi-longueur d'onde, de resoudre cette structure. Ce domaine adopte une conformation en homo-tetra-helice super enroulee qui n'avais jamais ete decrite dans le cas d'une proteine naturelle. Une etude par resonance magnetique nucleaire a ete initiee afin d'etudier le domaine de fixation a la nucleocapside. Cette etude nous permettra, en la couplant avec la structure resolue par cristallographie et les etudes de forme et de taille de modeliser l'ensemble du domaine necessaire a l'activite de transcription et ainsi de mieux apprehender les mecanismes d'action et les contacts entre les proteines impliquees dans la synthese d'arn par le virus.
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Ho, Ting-hin, and 何廷軒. "Immunostimulatory function of the defective interfering RNA of Sendai virus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/197496.

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The Cantell strain of Sendai virus (SeV-C) represents a typical laboratory attenuated virus which is less virulent and able to induce large amount of interferon in infected cells. This strain has widely been used in the laboratory for immunological studies due to its extraordinary ability to stimulate type I interferon production. Nevertheless, the underlying mechanism by which SeV-C is sensed by immune receptors as an invading microorganism is still largely unknown. Meanwhile, during the course of infection, Sendai virus is known to generate substantial amount of non-infectious viral particles consisting of defective interfering RNAs (DI RNAs) from replication errors. It was known that one major form of DI RNAs generated by some negative stranded RNA viruses may adopt a stem-loop panhandle structure with a relatively long double stranded region. Therefore, we hypothesized that some SeV-C DI RNAs may bear structures similar to intermediate-length dsRNA recognized by cytosolic immune receptor RIG-I, thus triggering interferon production. In this study, three DI RNAs were successfully isolated from SeV-C infected cells. Particularly, one of them designated T4 was found to contain a double stranded region of 93 base pair, and it was capable of stimulating interferon β production when transfected to reporter cells. The immunostimulatory activity of T4 alone was as potent as that of SeV-C, suggesting that T4 would be the major component in attenuated virus SeV-C that activates type I interferon production. Furthermore, cellular dsRNA binding protein PACT was shown to play a role in T4 recognition by RIG-I. T4 binds to PACT and potently stimulates PACT-induced activation of RIG-I. The identification and characterization of T4 reveals the major immunostimulatory component in SeV-C. Our work defines a RIG-I agonist naturally produced during the course of viral infection and provides a new mechanism to explain virus attenuation. We also demonstrate the role of PACT in immune sensing of a viral RNA. In addition, our findings also provide new strategies for the design and development of vaccines, vaccine adjuvants and other immunostimulatory agents.
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Biochemistry
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Master of Philosophy
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Okumura, Yutaka. "Mass Balance and Bioaccumulation of Major Dioxins in Sendai Bay." Kyoto University, 2011. http://hdl.handle.net/2433/135409.

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Séchoy, Odile. "Étude des interactions membranaires de la protéine F du virus Sendai." Montpellier 2, 1987. http://www.theses.fr/1987MON20222.

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Séchoy, Odile. "Etude et interactions membranaires de la protéine F du virus Sendai." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376098311.

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Goto, Kazuya. "Simple Derivation of Spinal Motor Neurons from ESCs/iPSCs Using Sendai Virus Vectors." Kyoto University, 2017. http://hdl.handle.net/2433/226763.

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Piga, Nadia. "Profil fonctionnel des glycoprotéines du virus Sendai (6/94) : conservation des épitopes chez les paramyxovirus et leur rôle dans la protection." Lyon 1, 1989. http://www.theses.fr/1989LYO1T052.

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Beiser, Sylvia. "Trends und Visionen im modernen Bibliotheksbau mit den Beispielen Seattle Public Library, Sendai Médiathèque, Phoenix Central Library /." [S.l. : s.n.], 2004. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB11675712.

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Rocheleau, Jonathan V. "Membrane distribution and dynamics of a synthetic ganglioside and its interaction with sendai virus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0017/NQ58160.pdf.

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Touzelet, Oliver. "The generation characterization and exploitation of recombinant sendai virus (SeV) as a novel virus vector." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492483.

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Reverse genetics technology has facilitated the genetic manipulation of many nonsegmented negative strand RNA viruses (NNSV), including Sendai virus (SeV). It has provided the means to exploit SeV as a vector for vaccines or gene therapy, via insertion of extra-numeral transcription units (ENTU) encoding heterologous genes. SeV contains six contiguous genes flanked by the leader (Ld) and trailer (Tr) promoter sequences (3 'Ld-N-P-M-F-HN-L-Tr 5 '). Characterisation of an infectious clone containing the entire antigenome of SeV confirmed that it contained all elements necessary for recombinant (r)SeV rescue. We inserted a heterologous gene encoding respiratory syncytial virus (RSV) fusion (F) protein between the Nand P genes of SeV. A recombinant virus (rSeV/RSV F) was successfully rescued and expressed functional RSV F protein. Importantly, it induced protective immunity in a BALB/c mouse model, demonstrating its vaccine potential against RSV. A common consequence of ENTU insertion is growth attenuation. Therefore, we hypothesised that a rSey containing a bicistronic gene, in which the second cistron encodes a heterologous gene, would circumvent this limitation. To address this, we used a 9nucleotide sequence with known Internal Ribosome Entry Site (IRES) activity. Furthermore, . multiple linked repeats of this IRES increased the expression efficiency of the second cistron. We inserted the Renilla luciferase (rLlle) ORF, preceded by 1, 3 or 7 synthetic IRES copies within the SeV N gene 5' untranslated region. We successfully rescued the corresponding rSeVs, thereby confirming the feasibility of generating bicistronic NNSVs. We confirmed luciferase expression in infected cells and that the number of IRES copies influenced expression efficiency. However, luciferase activity was invariably lower than that from rSeV expressing rLuc from an ENTU. Importantly, and in contrast to rSeV ENTU constructs, our data demonstrated that bicistronic rSeVs were not growth attenuated. Therefore, our approach offers a novel way to express heterologous genes from NNSVs.
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Books on the topic "Sendai"

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Bolognesi, Marco. Sendai City. Rimini]: NFC edizioni, 2014.

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Hakubutsukan, Sendai-shi. Sendai-han no kaiga: Paintings of Sendai Han. Sendai-shi: Sendai-shi Hakubutsukan, 1993.

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Nagai, Yoshiyuki, ed. Sendai Virus Vector. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9.

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Sendai Kanʼi Hoken Jimu Sentā (Japan), ed. Sendai Kanpo gojūnenshi. Sendai-shi: Sendai Kanʼi Hoken Jimu Sentā, 1985.

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Kenji, Asano. Sendai hōgen jiten. Tōkyō: Tōkyōdō Shuppan, 1985.

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Kenji, Asano. Sendai hōgen jiten. Tōkyō: Tōkyōdō Shuppan, 1985.

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Takakura, Kiyoshi. Sendai-han hankachō. Sendai-shi: Konno Insatsu Kabushiki Kaisha, 1995.

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Hakubutsukan, Sendai-shi. Sendai yondai gaka. Sendai-shi: Sendai-shi Hakubutsukan, 1997.

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Takakura, Jun. Sendai-han keibatsuki. Sendai-shi: Takakura Jun, 1988.

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Endō, Minoru. Sendai jidō bunkashi. Tōkyō: Kyūzansha, 1996.

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Book chapters on the topic "Sendai"

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Conzelmann, Karl-Klaus. "Reverse Genetics of Mononegavirales: The Rabies Virus Paradigm." In Sendai Virus Vector, 1–20. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_1.

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Nagai, Yoshiyuki, and Atsushi Kato. "Sendai Virus Biology and Engineering Leading up to the Development of a Novel Class of Expression Vector." In Sendai Virus Vector, 21–68. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_2.

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Iida, Akihiro, and Makoto Inoue. "Concept and Technology Underlying Sendai Virus (SeV) Vector Development." In Sendai Virus Vector, 69–89. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_3.

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Wiegand, Marian, and Wolfgang J. Neubert. "Genome Replication-Incompetent Sendai Virus Vaccine Vector Against Respiratory Viral Infections That Is Capable of Eliciting a Broad Spectrum of Specific Immune Response." In Sendai Virus Vector, 91–126. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_4.

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Seki, Sayuri, and Tetsuro Matano. "Development of Vaccines Using SeV Vectors Against AIDS and Other Infectious Diseases." In Sendai Virus Vector, 127–49. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_5.

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Yonemitsu, Yoshikazu, Yasuji Ueda, and Mamoru Hasegawa. "BioKnife, a Modified Sendai Virus, to Resect Malignant Tumors." In Sendai Virus Vector, 151–69. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_6.

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Fusaki, Noemi, and Hiroshi Ban. "Induction of Human Pluripotent Stem Cells by the Sendai Virus Vector: Establishment of a Highly Efficient and Footprint-Free System." In Sendai Virus Vector, 171–83. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_7.

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Yonemitsu, Yoshikazu, Takuya Matsumoto, and Yoshihiko Maehara. "Gene Therapy for Peripheral Arterial Disease Using Sendai Virus Vector: From Preclinical Studies to the Phase I/IIa Clinical Trial." In Sendai Virus Vector, 185–99. Tokyo: Springer Japan, 2013. http://dx.doi.org/10.1007/978-4-431-54556-9_8.

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Krüger, Marco, and Friedrich Gabel. "From Lisbon to Sendai." In The Routledge Handbook on Responsibility in International Relations, 203–16. London: Routledge, 2021. http://dx.doi.org/10.4324/9780429266317-15.

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Kondo, Tamiyo. "Miyagi Prefecture, Sendai, Japan." In Landscape Architecture for Sea Level Rise, 154–63. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003183419-19.

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Conference papers on the topic "Sendai"

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Polivka, Adam, Miroslav Houdek, Pieter Bastiaan Ober, and Michel Tossaint. "Satellite navigation data mining (SENDAI)." In 2015 International Association of Institutes of Navigation World Congress (IAIN). IEEE, 2015. http://dx.doi.org/10.1109/iain.2015.7352225.

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SHINOZUKA, T. "RIB PROJECTS OF SENDAI NEW CYCLOTRON." In Proceedings of the 4th Italy-Japan Symposium. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812791320_0035.

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SHIMIZU, H. "NEW γ BEAM LINE AT LNS SENDAI." In Proceedings of the International Symposium. WORLD SCIENTIFIC, 2004. http://dx.doi.org/10.1142/9789812702920_0030.

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Shirotori, K. "THE γ-RAY SPECTROSCOPY OF LIGHT HYPERNUCLEI AT J-PARC (E13)." In Proceedings of the Sendai International Symposium. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814277860_0065.

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Imai, Ken'ichi. "EXPERIMENTAL OVERVIEW AND CHALLENGE IN STRANGENESS NUCLEAR PHYSICS: STRANGENESS IN THE PAST AND COMING DECADES." In Proceedings of the Sendai International Symposium. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814277860_0003.

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Oka, Makoto. "RECENT QCD RESULTS ON THE STRANGE HADRON SYSTEMS." In Proceedings of the Sendai International Symposium. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814277860_0004.

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Burkert, Volker D. "STRANGENESS PHYSICS WITH CLAS." In Proceedings of the Sendai International Symposium. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814277860_0005.

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Mart, T. "PROGRESS AND ISSUES IN THE ELECTROMAGNETIC PRODUCTION OF KAON ON THE NUCLEON." In Proceedings of the Sendai International Symposium. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814277860_0006.

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Thomas, A. W. "IMPORTANCE OF STRANGE QUARKS IN HADRONS, NUCLEI AND DENSE MATTER." In Proceedings of the Sendai International Symposium. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814277860_0001.

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Gal, Avraham. "OVERVIEW OF STRANGENESS NUCLEAR PHYSICS." In Proceedings of the Sendai International Symposium. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814277860_0002.

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Reports on the topic "Sendai"

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Hobbs, T. E., J. M. Journeay, A. S. Rao, L. Martins, P. LeSueur, M. Kolaj, M. Simionato, et al. Scientific basis of Canada's first public national seismic risk model. Natural Resources Canada/CMSS/Information Management, 2022. http://dx.doi.org/10.4095/330927.

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Natural Resources Canada, in partnership with the Global Earthquake Model Foundation, has prepared a public Canadian Seismic Risk Model to support disaster risk reduction efforts across industry and all levels of government, and to aid in Canada's adoption of the Sendai Framework for Disaster Risk Reduction. Developing this model has involved the creation of a national exposure inventory, Canadian specific fragility and vulnerability curves, and adjustment of the Canadian Seismic Hazard Model which forms the basis for the seismic provisions of the National Building Code of Canada. Using the Global Earthquake Model Foundation's OpenQuake Engine (OQ), risk modelling is completed using both deterministic and probabilistic risk calculations, under baseline and simulated retrofit conditions. Output results are available in all settled regions of Canada, at the scale of a neighbourhood or smaller. We report on expected shaking damage to buildings, financial losses, fatalities, and other impacts such as housing disruption and the generation of debris. This paper documents the technical details of the modelling approach including a description of novel datasets in use, as well as preliminary results for a magnitude 9.0 earthquake on the Cascadia megathrust and nation-wide 500 year expected probabilistic losses. These kinds of results, such as earthquake scenario impacts, loss exceedance curves, and annual average losses, provide a quantitative base of evidence for decision making at local, regional, and national levels.
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Perera, Duminda, Ousmane Seidou, Jetal Agnihotri, Mohamed Rasmy, Vladimir Smakhtin, Paulin Coulibaly, and Hamid Mehmood. Flood Early Warning Systems: A Review Of Benefits, Challenges And Prospects. United Nations University Institute for Water, Environment and Health, August 2019. http://dx.doi.org/10.53328/mjfq3791.

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Floods are major water-related disasters that affect millions of people resulting in thousands of mortalities and billiondollar losses globally every year. Flood Early Warning Systems (FEWS) - one of the floods risk management measures - are currently operational in many countries. The UN Office for Disaster Risk Reduction recognises their importance and strongly advocates for an increase in their availability under the targets of the Sendai Framework for Disaster Risk Reduction, and Sustainable Development Goals (SDGs). However, despite widespread recognition of the importance of FEWS for disaster risk reduction (DRR), there’s a lack of information on their availability and status around the world, their benefits and costs, challenges and trends associated with their development. This report contributes to bridging these gaps by analyzing the responses to a comprehensive online survey with over 80 questions on various components of FEWS (risk knowledge, monitoring and forecasting, warning dissemination and communication, and response capabilities), investments into FEWS, their operational effectiveness, benefits, and challenges. FEWS were classified as technologically “basic”, “intermediate” and “advanced” depending on the existence and sophistication of FEWS` components such as hydrological data = collection systems, data transfer systems, flood forecasting methods, and early warning communication methods. The survey questionnaire was distributed to flood forecasting and warning centers around the globe; the primary focus was developing and least-developed countries (LDCs). The questionnaire is available here: https://inweh.unu.edu/questionnaireevaluation-of-flood-early-warning-systems/ and can be useful in its own right for similar studies at national or regional scales, in its current form or with case-specific modifications. Survey responses were received from 47 developing (including LDCs) and six developed countries. Additional information for some countries was extracted from available literature. Analysis of these data suggests the existence of an equal number of “intermediate” and “advanced” FEWS in surveyed river basins. While developing countries overall appear to progress well in FEWS implementation, LDCs are still lagging behind since most of them have “basic” FEWS. The difference between types of operational systems in developing and developed countries appear to be insignificant; presence of basic, intermediate or advanced FEWS depends on available investments for system developments and continuous financing for their operations, and there is evidence of more financial support — on the order of USD 100 million — to FEWS in developing countries thanks to international aid. However, training the staff and maintaining the FEWS for long-term operations are challenging. About 75% of responses indicate that river basins have inadequate hydrological network coverage and back-up equipment. Almost half of the responders indicated that their models are not advanced and accurate enough to produce reliable forecasts. Lack of technical expertise and limited skilled manpower to perform forecasts was cited by 50% of respondents. The primary reason for establishing FEWS, based on the survey, is to avoid property damage; minimizing causalities and agricultural losses appear to be secondary reasons. The range of the community benefited by FEWS varies, but 55% of FEWS operate in the range between 100,000 to 1 million of population. The number of flood disasters and their causalities has declined since the year 2000, while 50% of currently operating FEWS were established over the same period. This decline may be attributed to the combined DRR efforts, of which FEWS are an integral part. In lower-middle-income and low-income countries, economic losses due to flood disasters may be smaller in absolute terms, but they represent a higher percentage of such countries’ GDP. In high-income countries, higher flood-related losses accounted for a small percentage of their GDP. To improve global knowledge on FEWS status and implementation in the context of Sendai Framework and SDGs, the report’s recommendations include: i) coordinate global investments in FEWS development and standardise investment reporting; ii) establish an international hub to monitor the status of FEWS in collaboration with the national responsible agencies. This will support the sharing of FEWS-related information for accelerated global progress in DRR; iii) develop a comprehensive, index-based ranking system for FEWS according to their effectiveness in flood disaster mitigation. This will provide clear standards and a roadmap for improving FEWS’ effectiveness, and iv) improve coordination between institutions responsible for flood forecasting and those responsible for communicating warnings and community preparedness and awareness.
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3

Kucherawy, M. Resolution of the Sender Policy Framework (SPF) and Sender ID Experiments. RFC Editor, July 2012. http://dx.doi.org/10.17487/rfc6686.

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Lyon, J., and M. Wong. Sender ID: Authenticating E-Mail. RFC Editor, April 2006. http://dx.doi.org/10.17487/rfc4406.

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5

Kumar, Prasanna. A Remark on Sendov Conjectur. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, June 2018. http://dx.doi.org/10.7546/crabs.2018.06.01.

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6

Bashyam, M., M. Jethanandani, and A. Ramaiah. TCP Sender Clarification for Persist Condition. RFC Editor, December 2011. http://dx.doi.org/10.17487/rfc6429.

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7

Troth, R. SIFT/UFT: Sender-Initiated/Unsolicited File Transfer. RFC Editor, July 1993. http://dx.doi.org/10.17487/rfc1440.

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8

Graff, C. IPv4 Option for Sender Directed Multi-Destination Delivery. RFC Editor, March 1995. http://dx.doi.org/10.17487/rfc1770.

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9

Journeay, M., P. LeSueur, W. Chow, and C L Wagner. Physical exposure to natural hazards in Canada. Natural Resources Canada/CMSS/Information Management, 2022. http://dx.doi.org/10.4095/330012.

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Natural hazard threats occur in areas of the built environment where buildings, people, and related financial assets are exposed to the physical effects of earth system processes that have a potential to cause damage, injuries, losses, and related socioeconomic disruption. As cities, towns, and villages continue to expand and densify in response to the pressures of urban growth and development, so too do the levels of exposure and susceptibility to natural hazard threat. While our understanding of natural hazard processes has increased significantly over the last few decades, the ability to assess both overall levels of physical exposure and the expected impacts and consequences of future disaster events (i.e., risk) is often limited by access to an equally comprehensive understanding of the built environment and detailed descriptions of who and what are situated in harm's way. This study addresses the current gaps in our understanding of physical exposure to natural hazards by presenting results of a national model that documents characteristics of the built environment for all settled areas in Canada. The model (CanEM) includes a characterization of broad land use patterns that describe the form and function of cities, towns, and villages of varying size and complexity, and the corresponding portfolios of people, buildings and related financial assets that make up the internal structure and composition of these communities at the census dissemination area level. Outputs of the CanEM model are used to carry out a preliminary assessment of exposure and susceptibility to significant natural hazard threats in Canada including earthquake ground shaking; inundation of low-lying areas by floods and tsunami; severe winds associated with hurricanes and tornados; wildland urban interface fire (wildfire); and landslides of various types. Results of our assessment provide important new insights on patterns of development and defining characteristics of the built environment for major metropolitan centres, rural and remote communities in different physiographic regions of Canada, and the effects of ongoing urbanization on escalating disaster risk trends at the community level. Profiles of physical exposure and hazard susceptibility described in this report are accompanied by open-source datasets that can be used to inform local and/or regional assessments of disaster risk, community planning and emergency management activities for all areas in Canada. Study outputs contribute to broader policy goals and objectives of the International Sustainable Development Goals (SDG 2015-2030; Un General Assembly, 2015) and the Sendai Framework for Disaster Risk Reduction (SFDRR 2015-2030; United Nations Office for Disaster Reduction [UNDRR], 2015), of which Canada is a contributing member. These include a more complete understanding of natural hazard risk at all levels of government, and the translation of this knowledge into actionable strategies that are effective in reducing intrinsic vulnerabilities of the built environment and in strengthening the capacity of communities to withstand and recover from future disaster events.
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Divakaran, Ajay, Jeffrey Lubin, and Joe Ferraro. Sensei: A Multi-Modal Framework for Assessing Stress Resiliency. Fort Belvoir, VA: Defense Technical Information Center, April 2013. http://dx.doi.org/10.21236/ada578627.

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