Academic literature on the topic 'Sennoside'

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Journal articles on the topic "Sennoside"

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Ratnayaka, H. H., B. Meurer-Grimes, and D. Kincaid. "Sennoside Yields in Tinnevelly Senna Affected by Deflowering and Leaf Maturity." HortScience 37, no. 5 (2002): 768–72. http://dx.doi.org/10.21273/hortsci.37.5.768.

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Manual deflowering and leaf maturity were evaluated for effect on the yields of the bioactive sennosides A and B in Tinnevelly senna (Cassia angustifolia Vahl). Deflowering increased sennoside A and B concentration (percent dry weight) in leaves by 25%, the total leaf dry mass by 63%, and the harvest index by 22%, with the result that the sennoside A and B yield (grams) per plant doubled in response to deflowering. During the same time, net photosynthesis remained consistently lower in the deflowered plants. Youngest leaves had the greatest sennoside A and B concentration. A clone raised from cuttings of one seedling had lower sennoside A:B ratio than the plants raised from the seedlings. Although crop type and possibly environmental conditions influenced the sennoside A:B ratio, deflowering and leaf maturity had no effect. The sennoside A and B concentrations in the dried leaves of deflowered plants harvested in 1.5-hour intervals appeared to increase during the course of the day. Deflowering, harvesting of young leaves, and harvesting time of day constitute promising component technologies for field investigations.
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Wei, Zhonghong, Peiliang Shen, Peng Cheng, Yin Lu, Aiyun Wang, and Zhiguang Sun. "Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits." Oxidative Medicine and Cellular Longevity 2020 (June 25, 2020): 1–16. http://dx.doi.org/10.1155/2020/2375676.

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Accumulating evidences implicate that gut microbiota play an important role in the onset and prolongation of fat inflammation and diabetes. Sennoside A, the main active ingredient of Rhizoma Rhei (rhubarb), is widely used for constipation as a kind of anthranoid laxative (e.g., senna). Here, we put forward the hypothesis that the structural alteration of gut microbiota in obesity mice may be involved in the pathogenesis of type 2 diabetes (T2D) which may be ameliorated by Sennoside A. We investigated the appearance of obesity, insulin resistance, host inflammation, and leaky gut phenotype with or without Sennoside A in db/db mice. Horizontal fecal microbiota transplantation (FMT) was used to confirm the critical roles of gut microbiota in the amelioration of the indices in T2D mice after Sennoside A treatment. As a result, we found that Sennoside A administration markedly improved the indices in T2D mice and obesity-related traits including blood glucose level, body weight, lipid metabolism disorder, and insulin resistance. The gut microbiota changed quickly during the onset of T2D in db/db mice, which confirmed the hypothesis that gut microbiota was involved in the pathogenesis of T2D. Sennoside A altered gut microbial composition which might mediate the antiobesogenic effects in T2D remission. Sennoside A also reduced inflammation and increased tight junction proteins in the ileum in gene-deficient mice via gut microbiota alteration. FMT lowered the blood glucose level and improved insulin resistance, corroborating that Sennoside A perhaps exerted its antiobesogenic effects through gut microbiota alteration. Chemical Compounds Studied in This Article. Compounds studied in this article include Sennoside A (PubChem CID: 73111) and metformin hydrochloride (PubChem CID: 14219).
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Morinaga, Osamu, Takuhiro Uto, Seiichi Sakamoto, et al. "Development of eastern blotting technique for sennoside A and sennoside B using anti-sennoside A and anti-sennoside B monoclonal antibodies." Phytochemical Analysis 20, no. 2 (2009): 154–58. http://dx.doi.org/10.1002/pca.1111.

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Tan, Peng, Yan-ling Zhao, Jun-ling Cao, Xiao-he Xiao, and Jia-bo Wang. "Development and validation of ultra-high-performance liquid chromatography for the determination of sennoside A and sennoside B in laxatives based on optimal chromatographic parameters." Analytical Methods 7, no. 23 (2015): 9817–24. http://dx.doi.org/10.1039/c5ay02458g.

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Srivastava, Alpana, Richa Pandey, Ram K. Verma, and Madan M. Gupta. "Liquid Chromatographic Determination of Sennosides in Cassia angustifolia Leaves." Journal of AOAC INTERNATIONAL 89, no. 4 (2006): 937–41. http://dx.doi.org/10.1093/jaoac/89.4.937.

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Abstract A simple liquid chromatographic method was developed for the determination of sennosides B and A in leaves of Cassia angustifolia. These compounds were extracted from leaves with a mixture of methanolwater (70 + 30, v/v) after defatting with hexane. Analyte separation and quantitation were achieved by gradient reversed-phase liquid chromatography and UV absorbance at 270 nm using a photodiode array detector. The method involves the use of an RP-18 Lichrocart reversed-phase column (5 μm, 125 × 4.0 mm id) and a binary gradient mobile-phase profile. The various other aspects of analysis, namely, peak purity, similarity, recovery, repeatability, and robustness, were validated. Average recoveries of 98.5 and 98.6%, with a coefficient of variation of 0.8 and 0.3%, were obtained by spiking sample solution with 3 different concentration solutions of standards (60, 100, and 200 μg/mL). Detection limits were 10 μg/mL for sennoside B and 35 μg/ML for sennoside A, present in the sample solution. The quantitation limits were 28 and 100 μg/mL. The analytical method was applied to a large number of senna leaf samples. The new method provides a reliable tool for rapid screening of C. angustifolia samples in large numbers, which is needed in breeding/genetic engineering and genetic mapping experiments.
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Dutta, A., and B. De. "CASSIA FISTULA: A SOURCE OF SENNOSIDE B (CHROMOSOME MORPHOLOGY AND SENNOSIDE CONTENT)." Acta Horticulturae, no. 576 (April 2002): 45–48. http://dx.doi.org/10.17660/actahortic.2002.576.6.

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SATOH, Kanako, Takako SETO, Norie MIYATAKE, Tomoko HAMANO, Hiroko SHIODA, and Kazuo ONISHI. "Determination of Sennoside A and Sennoside B in Formulation Using Capillary Electrophoresis." YAKUGAKU ZASSHI 119, no. 1 (1999): 88–92. http://dx.doi.org/10.1248/yakushi1947.119.1_88.

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Peng, Lei, Prasannavenkatesh Durai, Keunwan Park, Jeong Joo Pyo та Yongsoo Choi. "A Novel Competitive Binding Screening Assay Reveals Sennoside B as a Potent Natural Product Inhibitor of TNF-α". Biomedicines 9, № 9 (2021): 1250. http://dx.doi.org/10.3390/biomedicines9091250.

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Natural products (NPs) have played a significant role in drug discovery for diverse diseases, and numerous attempts have been made to discover promising NP inhibitors of tumor necrosis factor α (TNF-α), a major therapeutic target in autoimmune diseases. However, NP inhibitors of TNF-α, which have the potential to be developed as new drugs, have not been reported for over a decade. To facilitate the search for new promising inhibitors of TNF-α, we developed an efficient competitive binding screening assay based on analytical size exclusion chromatography coupled with liquid chromatography-tandem mass spectrometry. Application of this screening method to the NP library led to the discovery of a potent inhibitor of TNF-α, sennoside B, with an IC50 value of 0.32 µM in TNF-α induced HeLa cell toxicity assays. Surprisingly, the potency of sennoside B was 5.7-fold higher than that of the synthetic TNF-α inhibitor SPD304. Molecular docking was performed to determine the binding mode of sennoside B to TNF-α. In conclusion, we successfully developed a novel competition binding screening method to discover small molecule TNF-α inhibitors and identified the natural compound sennoside B as having exceptional potency.
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AlZain, Mashail N., Abdulrahman A. AlAtar, Abdulaziz A. Alqarawi, et al. "The Influence of Mycorrhizal Fungi on the Accumulation of Sennosides A and B in Senna alexandrina and Senna italica." Separations 7, no. 4 (2020): 65. http://dx.doi.org/10.3390/separations7040065.

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Symbiotic arbuscular mycorrhizal fungi (AMF) play a major role in plant development, growth, and relationships with the environment through a change in the accumulation of secondary metabolites; hence, we planned to investigate AMF’s influence on sennoside A and B accumulation in Senna alexandrina (SA) and Senna italica (SI). Seeds of SA (S. alexandrina free of mycorrhizae) and SI (S. italica free of mycorrhizae) were planted in two types of soils: +mycorrhiza and—mycorrhiza. The plant leaves of SA, SI, S. alexandrina with mycorrhizae (SAM) and S. italica with mycorrhizae (SIM) were collected and extracted (with 85% methanol), and sennoside A and B content was evaluated by the HPLC–UV method. The antioxidant activity of SA, SI, SAM and SIM was evaluated by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods, while antimicrobial properties were evaluated by the minimum inhibitory concentration method (MIC). The AMF colonization was 85.66% and 85%, respectively, in the roots of SA and SI. The HPLC analysis showed a significant increase in (%) the content of sennoside A/sennoside B by 71.11/88.21, respectively, in SAM and 6.76/36.37 in SIM, which clearly indicated positive AMF effects. The DPPH/ABTS [The half maximal inhibitory concentration (IC50): 235.9/321.5 µg/mL] scavenging activity of SAM was comparatively higher and it also exhibited strong antibacterial action (MIC: 156.25 µg/mL), which supported the increase in sennoside content. This finding may be useful for further investigations of the symbiotic relation of mycorrhizal fungi with other plant species.
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Kon, Risako, Miho Yamamura, Yukari Matsunaga, et al. "Laxative effect of repeated Daiokanzoto is attributable to decrease in aquaporin-3 expression in the colon." Journal of Natural Medicines 72, no. 2 (2018): 493–502. http://dx.doi.org/10.1007/s11418-018-1174-1.

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Abstract Daiokanzoto (DKT) exerts its laxative effect via colonic inflammation caused by sennoside A in Daio (rhubarb). Previously, we showed that the laxative effect of sennoside A is related to decreased aquaporin-3 (AQP3) expression in mucosal epithelial cells due to colonic inflammation. We also found that a combination of glycyrrhizin, an ingredient in Kanzo (glycyrrhiza), and sennoside A attenuates the inflammatory response induced by sennoside A and reduces its laxative effect. These findings indicate that DKT may be a long-term treatment for chronic constipation, but there is no evidence supporting this hypothesis. In this study, we analyzed the laxative effect of repeated DKT administration, focusing on AQP3 expression in the colon. After rats were treated for 7 days, decreased AQP3 expression and the onset of diarrhea were observed in the DKT group, but were not seen in the Daio group either. Although the relative abundance of gut microbiota after repeated DKT administration was similar to that after control treatment, Daio reduced Lactobacillaceae, Bifidobacteriaceae, and Bacteroidaceae levels and markedly increased Lachnospiraceae levels. In this study, we show that DKT has a sustained laxative effect, even upon repeated use, probably because it maintains decreased AQP3 expression and gut microbiota homeostasis. This outcome therefore indicates that DKT can be used as a long-term treatment for chronic constipation.
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Dissertations / Theses on the topic "Sennoside"

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Masse, Patrick. "Drogues végétales à principes hydroxyanthracéniques: ètude pharmacologique et clinique des effets laxatifs." Paris 5, 1990. http://www.theses.fr/1990PA05P007.

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Malamoussi, Zoi. "Akuteffekt von Anthrachinonen (Sennosiden, Danthron), Bisacodyl und Na-Picosulphat auf den Gehalt von Somatostatin, VIP und Substanz P im Rattenkolon." Diss., kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/8672/.

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Lee, Li-Hua, and 李麗華. "Determination of contents of sennoside A and sennoside B in various commercial senna leaves containing tea bags by HPLC." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/17775186468210255098.

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碩士<br>國立臺灣海洋大學<br>食品科學系<br>99<br>Two different high performance liquid chromatographic columns: C8 and C18 were used to analyze the content of sennoside A and B in commercially available senna leaf tea bags. Chromatography conditions used by the C8 column were GL Sciences C8 column (5 μm, 4.6 mm × 250 mm), with the mobile phase of acetonitrile and 1% acetic acid solution in gradient elution mode, while the detection wavelength was set at 270 nm. The results revealed that the retention time of sennoside A was about 47 - 48 min, while that of sennoside B was about 53 - 54 min. The calibration curves for sennoside A and B showed good linearity. The linear regression equation of sennoside A was y = 4655.5x + 2217.6, and its coefficient of determination (R2) was 0.9983; the equation for sennoside B was y = 7932.7x + 1248.3, and its coefficient of determination was 0.9991. Chromatography conditions used by C18 column were Biosil C18 column (5 μm, 4.6 mm × 250 mm), with the mobile phase of acetonitrile and 1% acetic acid solution in linear gradient elution mode, while the detection wavelength was set at 270 nm. The results revealed that the retention time of sennoside A was about 22 - 23 min, while that of sennoside B was about 17 - 18 min. The calibration curves of sennoside A and B showed good linearity. The linear regression equation for sennoside A was y = 5424.9x - 29272, and its coefficient of determination was 0.9988; the equation for sennoside B was y = 10655x + 10468, and its coefficient of determination was 0.9993. Ten samples of commercially available senna leaf tea bags were also analyzed, and an extraction with 70% menthanol showed that the sennosides content of each bag was 2.18 - 41.73 mg. The Department of Health’s provision is that the total content of sennosides in food-grade senna tea leaf bags shall not exceed 12 mg. If the total content in each bag exceeds 12 mg, the product shall be managed as pharmaceutical grade. The test results indicated that the unsatisfactory rafio of commercially available senna tea leaf bags was 30%. Analysis with C8 and C18 columns revealed that two of the ten tested samples were significantly different in terms of the measured sennosides content, while the others were not much different in this regard. Retention time of C8 column was more than twice that of the C18 column. Despite the long retention time of C8 column, fewer interference peaks appeared in its chromatogram.
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Wen, Chia-Yun, and 溫嘉筠. "The use of a new generation column of high performance liquid chromatography, monolithic column, to analyze sennoside A and sennoside B in a senna tablet." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/97968472236430974907.

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碩士<br>國立臺灣大學<br>藥學研究所<br>93<br>Sennoside A and sennoside B are the most significant and abundant active components in senna tablets. Clinically, they are used for constipation treatment. However, overdose will cause tormina and severe diarrhea. In order to make sure and determine the doses of sennoside A and sennoside B effectively, this study employed one of the monolithic columns, ChromolithTM performance RP-18e. Compared to the traditional particle-packed column, this one is with lower column pressure and thus it can be analyzed under high flow rate to reduce separation time. In the course of method development, parameters including concentration and pH value of buffer solution, concentration of ion-pair reagents, volume of organic solvent modifier, column temperature and flow rate of the mobile phase were varied to find out the optimum conditions of separation. The most optimum conditions were : ChromolithTM performance RP-18e (100 �e 4.6 mm) as column, 0.1 M acetate buffer at pH 5.0 and ACN (70:30, v/v) containing 7 mM tetra-n-octylammonium bromide as mobile phase. Flow rate, temperature, and detection wavelength were set at 5 mL/min, 25℃, and 270 nm, respectively. Sennoside A and sennoside B could be separated from other components in 5 minutes. The optimum condition was validated with the tests of specificity, precision, linearity, limit of detection and accuracy. Plackett-Burman experimental design was adopted for the robustness test. The effects of five experimental factors, including concentration of ion-pair reagent, percentage of organic modifier (acetonitrile), pH and concentration of buffer and flow rate on four response factors, such as resolution, retention time, plate number and tailing factor were investigated. Five experimental factors mentioned above had significant effects on plate number of sennoside A. Concentration of ion-pair reagent, percentage of organic modifier and flow rate especially had greater effect on resolution.
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Chen, Rui-Yu, and 陳瑞宇. "I. Total synthesis of Sennoside A and B II. The Study of Asymmetric Nozaki-Hiyama-Kishi Reaction." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/8k5dh3.

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Lee, Chia-Ling, and 李佳玲. "Levels of sennoside A and B in the tea bag of senna leaves and effect of extracting temperature and time." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/51128807148072918438.

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碩士<br>國立臺灣海洋大學<br>食品科學系<br>92<br>Abstract A rapid HPLC method was developed for determination of sennoside A and B in the tea bag of senna leaves. Chromatographic condition consisted of column : Hypersil C18 (5 μm, 4.6 mm × 250 mm); mobile phase : acetonitrile and 1% acetic acid solution (pH 2.6) by gradient; detector wavelength : 270 nm. The pH value of mobile phase did not affect the retention time of sennoside A and B. The recovery was 101.06-102.56% for sennoside A and 95.83-106.10% for sennoside B, respectively. The linear standard curve was obtained and the detective range of sennoside A and B was 4-12 ppm. The standard curve of sennoside A was y = 36.232x – 5.328 (R2 = 0.9996), and that of sennoside B was y = 35.185x – 4.738 (R2 = 0.9997). After analyzing 11 tea bag samples of senna leaves sold in the markets, the contents of sennosides ranged from 1.48 to 29.72 mg per bag. According to the regulation of Department of Health, the content of sennosides for food grade must be less than 12 mg. The illegal rate was 36.36% (4/11) . Furthermore, the tea bag samples were separately soaked at 100℃、90℃、85℃、65℃ and 25℃. Although the extracted content of sennoside A and B was the highest at 100℃ for 5 min, others it was the highest at 90℃ for 15-60 min. The extracted content of sennosides was 30% when tea bag sample was soaked at 90℃ for 1 hour. The longer the soaking time was, the more sennosides the tea bag sample released. Also, sennosides was found to be unstable at high temperature (especially for over 80℃). Among both components, sennoside B was less stable than sennoside A. The decomposed rates of sennosides were increased as soaking temperature and time increased.
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Su, Hsiu-Ting, and 蘇秀婷. "Determination of sennosides A and B in a commercial Senna preparation by HPLC." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/11013898862988580336.

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碩士<br>國立臺灣大學<br>藥學研究所<br>89<br>This study developed an efficient and reliable ion-pair liquid chromatographic method for quantitation of sennosides A and B in a commercial Senna preparation. In the course of method development, parameters including the kind of column, type and concentration of ion-pair reagent, percentage of organic modifier in the mobile phase, buffer pH and the column temperature were varied to find out the optimum conditions of separation. The optimum conditions found were: a Hypersil C 18 column (250 ×4.6 mm, 5 mm) as stationay phase, a mixture of 0.1 M acetate buffer of pH 6.0 and acetonitrile (70:30, v/v) containing 5 mM tetrahexylammonium bromide as mobile phase, column temperature at 40°C. Flow rate and detection wavelength were set at 1.0 mL/min and 270 nm respectively. Sennosides A and B were completely separated from other constituents within 15 min. The developed method was validated with the tests of specificity, precision, linearity, accuracy and robustness. Both run-to-run repeatability (n = 10) and day-to-day reproducibility (n = 3) of peak area were below 0.4% RSD. Linearity of peak area was tested in the range 30-70 µg/mL (r > 0.9997). Accuracy was assessed with recovery and the recoveries for sennosides A and B were 101.73 ± 1.30% and 101.81 ± 2.18% (n = 3´6), respectively. Robustness of the analytical method was tested using a three-levelled Plackett-Burman design in which 11 factors were assessed with 23 experiments being carried out. Eight factors (column, concentration of ion pair reagent, volume % of organic modifier (acetonitrile), pH of buffer, column temperature, flow rate, time constant and detection wavelength) were investigated in a specified range above and below the nominal method conditions. It was found that: (1) column and % acetonitrile affected significantly resolution and retention time, (2) column, % acetonitrile, column temperature, flow rate and time constant affected significantly the plate number, and (3) column, column temperature and time constant affected significantly the tailing factor.
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Malamoussi, Zoi [Verfasser]. "Akuteffekt von Anthrachinonen (Sennosiden, Danthron), Bisacodyl und Na-Picosulphat auf den Gehalt von Somatostatin, VIP und Substanz P im Rattenkolon / vorgelegt von Zoi Malamoussi." 2008. http://d-nb.info/989817261/34.

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Yeh, Pei-Chen, and 葉佩真. "Part I: Analysis of anthraquinones and bianthrones in rhubarb by microemulsion electrokinetic chromatographyPart II: Analysis of sennosides A and B in commercial senna tablets by capillary zone electrophoresis." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/49105309866033143461.

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碩士<br>國立臺灣大學<br>藥學研究所<br>93<br>Part I: Analysis of anthraquinones and bianthrones in rhubarb by microemulsion electrokinetic chromatography Microemulsion eletrokinetic chromatograpy (MEEKC) is a separation technique which is similar in principle to micellar electrokinetic chromatography (MEKC), but with more parameters to be adjusted so as to obtain better separation results. The separation of nine anthraquinones and bianthrones in the present study was investigated for the key-operating variables such as the concentration and the type of surfactant, the type of oil phase, and the addition of organic solvent. The optimal condition was found to be 0.5% (w/w) di-n-butyl-L-tartrate, 1.2% (w/w) 1-butanol, 0.6% (w/w) SDS, 97.7% (w/w) 10 mM Na2B4O7 (pH 9.2) and ACN 30% (v/v), under which these nine compounds could be baseline separated within 20 minuntes. Owing to the complexity of rhubarb constituents, we used solid- phase extraction (SPE) for sample pretreatment. By utilizing suitable proportion of weak acid, weak base, and organic solvent for sample loading, washing, and eluting steps on an Oasis HLB sorbet, most of interference in the crude extracts of rhubarb could be cleaned off. The partially purified extracts with finely tuned concentrations could be injected into capillary electrophoresis. Thus, seven analytes were accurately quantitated. Part II: Analysis of sennoside A and sennoside B in commercial senna tablets by capillary zone electrophoresis Qualitative and quantitative analyses of sennoside A and sennoside B, the major cathartic constituents, in commercial senna tablets was performed in the present study by capillary zone electrophoresis. During the process of method development, we investigated the influence of possible parameters on resolution, including the type, concentration, and pH value of the buffer solution, the temperature, the applied voltage and the addition of organic solvent. The optimal condition was found to be 100 mM CAPS (pH 10.4) at 25 kV and 30�aC. To prevent the overlapping of the internal standard (phenol) with the components in senna, the condition was slightly modified to 120 mM CAPS (pH 10.25) at 25 kV and 25�aC. Compared with the condition developed initially (35 mM Na2B4O7, pH 9.0;ACN 15% (v/v);20 kV;30�aC), the final method possessed advantages of shorter analysis time, more stable baseline, smaller responding current, and void of organic solvent. Therefore, this method is an efficient and reliable for the analysis of the commercial senna formulation.
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Books on the topic "Sennoside"

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Dalal, Shalini. Docusate and Sennosides for Constipation (DRAFT). Edited by Nathan A. Gray and Thomas W. LeBlanc. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190658618.003.0024.

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This chapter describes a prospective study that ran from December 2005 to November 2010 using three hospital inpatient units of adding a stool softener, docusate versus placebo, to sennosides alone for the treatment of constipation among hospice patients. Patients were adults admitted to an inpatient hospice program with a Palliative Performance Status 20% or greater. The chapter describes the basics of the study, including funding, year study began, year study was published, study location, who was studied, who was excluded, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, gives a summary and discusses implications, and concludes with a relevant clinical case.
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Book chapters on the topic "Sennoside"

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Shibata, S. "Rheum Species (Rhubarb): In Vitro Culture and the Production of Sennosides." In Medicinal and Aromatic Plants IV. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77004-3_20.

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"S-II (Sennoside to Spongiane)." In RÖMPP Lexikon Naturstoffe, edited by Wolfgang Steglich, Burkhard Fugmann, and Susanne Lang-Fugmann. Georg Thieme Verlag, 1997. http://dx.doi.org/10.1055/b-0036-133865.

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Morinaga, Osamu, and Yukihiro Shoyam. "Quality Control of Rheum and Cassia Species by Immunological Methods Using Monoclonal Antibodies Against Sennosides." In Latest Research into Quality Control. InTech, 2012. http://dx.doi.org/10.5772/51272.

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Conference papers on the topic "Sennoside"

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Meier, N., B. Meier, S. Peter, G. Josic, and E. Wolfram. "Photostability of sennosides in solution and their degradation products 1." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608273.

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Meier, N., B. Meier, S. Peter, and E. Wolfram. "HPTLC fingerprint method for the detection of sennosides in Senna dry extracts." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608524.

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Schenk, A., LN Ziegler, N. Meier, S. Peter, and E. Wolfram. "Combined determination of sennosides, monomeric hydroxyanthacene glycosides and anthraquinone aglycones by UHPLC-DAD." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608215.

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Siddique, Iram. "In vitro organogenesis from epicotyl explants in Cassia angustifolia Vahl. An important source of Sennosides." In 3rd Annual International Conference on Advances in Biotechnology (BioTech 2013). Global Science and Technology Forum, 2013. http://dx.doi.org/10.5176/2251-2489_biotech13.23.

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