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1

Ahmed, Sara S., Jabbar S. Hassan, and Qahtan A. Mahdi. "Detection of The Quaternary Ammonium Compound Antiseptic Resistance Gene (qac A/B qac C and qac E gene) In Pseudomonas Aeruginosa Recovered from Topical Wound Infection." International Journal of Membrane Science and Technology 10, no. 4 (2023): 1983–91. http://dx.doi.org/10.15379/ijmst.v10i4.2340.

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Background: Quaternary ammonium compounds (QACs) have represented one of the most visible and effective classes of antiseptics and disinfectants substances that used in different parts of life including food production, water treatment and healthcare such as hospitals to prevent infections and intoxications. The increased use of disinfectants containing quaternary ammonium compounds (QACs) has raised concerns about the development of resistance. Aim of the study: this study pursues to determination frequency of antiseptic resistant Quaternary Ammonium Compound (qacA/B, qacC and qacE gene) in P
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2

Castro, Vinicius Silva, Yuri Duarte Porto, Xianqin Yang, Carlos Adam Conte Junior, Eduardo Eustáquio de Souza Figueiredo, and Kim Stanford. "The Trade-Off Between Sanitizer Resistance and Virulence Genes: Genomic Insights into E. coli Adaptation." Antibiotics 14, no. 3 (2025): 291. https://doi.org/10.3390/antibiotics14030291.

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Background: Escherichia coli is one of the most studied bacteria worldwide due to its genetic plasticity. Recently, in addition to characterizing its pathogenic potential, research has focused on understanding its resistance profile to inhibitory agents, whether these be antibiotics or sanitizers. Objectives: The present study aimed to investigate six of the main serogroups of foodborne infection (O26, O45, O103, O111, O121, and O157) and to understand the dynamics of heterogeneity in resistance to sanitizers derived from quaternary ammonium compounds (QACs) and peracetic acid (PAA) using whol
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Yang, Peng, Bing Li, Cong-Yi Lv, Qi-Feng Yin, and Yu-Juan Wang. "Cationic Quaternized Chitosan Nanoparticles for C-phycocyanin Delivery to Hela Cells." International Journal of Sciences Volume 4, no. 2015-09 (2015): 17–23. https://doi.org/10.5281/zenodo.3349007.

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In this study we synthesize C-PC/QAC nanoparticles using cationic quaternary ammonium chitosan (QAC) as substrate material loaded C-phycocyanin (C-PC) by ionic-gelation method. The prepared NPs was about 120nm size with spherical morphology, the entrapment efficient was 62%, and the drug-loading amount was 20%. The NPs exhibited a pH sensitive realease of C-PC in vitro. The drug-NPs were proved to be hemocompatible and safe. In conclusion, QAC increased bioavailability and anticancer property of C-PC.Read Complete Article at ijSciences: V4201509834 AND DOI: http://dx.doi.org/10.18483/ijSci.834
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4

Grillitsch, B., O. Gans, N. Kreuzinger, S. Scharf, M. Uhl, and M. Fuerhacker. "Environmental risk assessment for quaternary ammonium compounds: a case study from Austria." Water Science and Technology 54, no. 11-12 (2006): 111–18. http://dx.doi.org/10.2166/wst.2006.840.

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Quaternary ammonium compounds (QAC) are widely used as disinfectants, biocides, and detergents, among a variety of other applications. The cationic surface-activity of QAC determines their potential to act as a biocide on both target and non-target organisms. This study aims to provide a broad-based environmental risk characterization and evaluation for selected QAC with particular focus on the situation in Austrian rivers. A modular study design was employed involving environmental exposure characterization, QAC fate and effect analysis in wastewater, ecotoxicological effect characterization,
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Antosik, Adrian Krzysztof, Karolina Mozelewska, Magdalena Zdanowicz, Konrad Gziut, and Piotr Miądlicki. "Organophilized Montmorillonites as Fillers for Silicone Pressure-Sensitive Adhesives." Materials 16, no. 3 (2023): 950. http://dx.doi.org/10.3390/ma16030950.

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In the presented work, organophilized montmorillonites (OMMT) with selected quaternary ammonium compounds (QAC) with different chemical structure ((trioctylmethylammonium chloride—A336, dimethyloctadecyl[3-trimethoxysilyl)propyl]ammonium chloride—D, cetyltrimethylammonium bromide—CTAB, 2-methacryloxyethyltrimethylammonium chloride—MOA) were obtained and used as fillers for physically modified silicone pressure-sensitive adhesives (Si-PSA). Before OMMT addition into Si-PSA matrix, they were analyzed via TGA and XRD techniques. Type of chemical structure of QAC affected d-spacing of OMMT. New se
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Jiang, Danyang, Honghui Chen, and Fei Cai. "Exploiting Query’s Temporal Patterns for Query Autocompletion." Mathematical Problems in Engineering 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/7490879.

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Query autocompletion (QAC) is a common interactive feature of web search engines. It aims at assisting users to formulate queries and avoiding spelling mistakes by presenting them with a list of query completions as soon as they start typing in the search box. Existing QAC models mostly rank the query completions by their past popularity collected in the query logs. For some queries, their popularity exhibits relatively stable or periodic behavior while others may experience a sudden rise in their query popularity. Current time-sensitive QAC models focus on either periodicity or recency and ar
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7

Sidhu, Maan Singh, Even Heir, Truls Leegaard, Karianne Wiger та Askild Holck. "Frequency of Disinfectant Resistance Genes and Genetic Linkage with β-Lactamase Transposon Tn552 among Clinical Staphylococci". Antimicrobial Agents and Chemotherapy 46, № 9 (2002): 2797–803. http://dx.doi.org/10.1128/aac.46.9.2797-2803.2002.

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ABSTRACT A total of 61 strains of Staphylococcus aureus and 177 coagulase-negative staphylococcal strains were isolated from the blood of patients with bloodstream infections and from the skin of both children under cancer treatment and human immunodeficiency virus-positive patients. The MIC analyses revealed that 118 isolates (50%) were resistant to quaternary ammonium compound-based disinfectant benzalkonium chloride (BC). The frequencies of resistance to a range of antibiotics were significantly higher among BC-resistant staphylococci than among BC-sensitive staphylococci. Of 78 BC-resistan
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8

He, Gui-Xin, Michael Landry, Huizhong Chen, et al. "Detection of benzalkonium chloride resistance in community environmental isolates of staphylococci." Journal of Medical Microbiology 63, no. 5 (2014): 735–41. http://dx.doi.org/10.1099/jmm.0.073072-0.

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We isolated a total of 653 strains from 64 community environmental samples in Massachusetts, USA. Among these isolates, 9.65 % (63 strains) were benzalkonium chloride (BC)-resistant staphylococci. All BC-resistant strains were collected from surfaces upon which antibacterial wipes or antibacterial sprays containing 0.02–0.12 % BC had frequently been used in the fitness centres. However, isolates from surfaces upon which antibacterial wipes or antibacterial sprays had not been used were all sensitive to BC. All BC-resistant strains were also resistant to erythromycin, penicillin and ampicillin.
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9

Ibrahim, Waleed A., Sherif A. Marouf, Ahmed M. Erfan, Soad A. Nasef, and Jakeen K. El Jakee. "The occurrence of disinfectant and antibiotic-resistant genes in Escherichia coli isolated from chickens in Egypt." Veterinary World 12, no. 1 (2019): 141–45. http://dx.doi.org/10.14202/vetworld.2019.141-145.

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Aim: This work aimed to determine the occurrence of antibiotic and disinfectant resistance genes in Escherichia coli isolated from chickens in Egypt. Materials and Methods: Organs (liver, lung, heart, yolk sac, and bone marrow) of 1500 chicken samples were collected from diseased chickens suffered from colibacillosis with PM findings as CRD, diarrhea and omphalitis from different governorates of Egypt as: Giza, EL-Bahira, Fayoum, El-Dakahlia, El-Ismalia, and El-Sharkia during 2015-2016. These samples were labeled and transported immediately on ice to the Reference laboratory for quality contro
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10

Biswas, Saswati, and Indranil Biswas. "Role of VltAB, an ABC Transporter Complex, in Viologen Tolerance inStreptococcus mutans." Antimicrobial Agents and Chemotherapy 55, no. 4 (2011): 1460–69. http://dx.doi.org/10.1128/aac.01094-10.

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ABSTRACTStreptococcus mutans, a Gram-positive organism, is the primary causative agent in the formation of dental caries in humans. To persist in the oral cavity,S. mutansmust be able to tolerate rapid environmental fluctuations and exposure to various toxic chemicals. However, the mechanisms underlying the ability of this cariogenic pathogen to survive and proliferate under harsh environmental conditions remain largely unknown. Here, we wanted to understand the mechanisms by whichS. mutanswithstands exposure to methyl viologen (MV), a quaternary ammonium compound (QAC) that generates superoxi
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11

Tomat, David, Cecilia Casabonne, Virginia Aquili, and Andrea Quiberoni. "Evaluation of Food-Grade Additives on the Viability of Ten Shigella flexneri Phages in Food to Improve Safety in Agricultural Products." Viruses 17, no. 4 (2025): 474. https://doi.org/10.3390/v17040474.

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Bacteriophages can be used as biocontrol agents in agriculture to improve food safety, provided they can remain viable in food environments. The viability of ten Shigella phages (AShi, Shi3, Shi22, Shi30, Shi33, Shi34, Shi40, Shi88, Shi93, and Shi113) was evaluated against different additives and biocides used daily in food applications. In addition, the influence of additives on phage viability in a food matrix was investigated. Treatments with lactic and citric acid were the most effective to inactivate phages. In addition, the acetic acid was the most phage-friendly treatment evaluated. Pre
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12

Hanczvikkel, Adrienn, András Víg, and Ákos Tóth. "Survival capability of healthcare-associated, multidrug-resistant bacteria on untreated and on antimicrobial textiles." Journal of Industrial Textiles 48, no. 7 (2018): 1113–35. http://dx.doi.org/10.1177/1528083718754901.

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Healthcare-associated infections are of global concern, and textiles can contribute to the transmission of pathogens. In this study, we examined quantitatively the survival capability of 60 multidrug-resistant bacterial strains from four species ( Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus and Enterococcus faecium) on untreated cotton textile in clinically relevant incubation periods. We determined the antibacterial efficiency of textiles treated either with quaternary ammonium compound (QAC)-containing Sanitized T99-19 liquid (50 m/m% Dimethyltetradecyl (3-(trimetho
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13

Soloski, M. J., A. Lattimore, D. Hereld, J. L. Krakow, M. G. Low, and G. Einhorn. "Further characterization of the membrane anchor found on the tissue-specific class I molecule Qa2." Journal of Immunology 140, no. 11 (1988): 3858–66. http://dx.doi.org/10.4049/jimmunol.140.11.3858.

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Abstract Previous studies have determined that various Qa2 serologic determinants can be removed from the surface of spleen cells by treatment with a phospholipase C. Our studies have determined that the class I molecule Qa2, expressed on the surface of spleen cells and activated T cells, behaves as an integral membrane protein based on its ability to associate with detergent micelles. Studies utilizing two purified phospholipase C have revealed that although most (90 to 95%) of the Qa2 molecules expressed on the surface of resting spleen cells are released as intact 40-kDa polypeptides associ
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14

Bardasheva, Alevtina, Artem Tikunov, Yuliya Kozlova, et al. "Antibiotic Resistance and Pathogenomics of Staphylococci Circulating in Novosibirsk, Russia." Microorganisms 9, no. 12 (2021): 2487. http://dx.doi.org/10.3390/microorganisms9122487.

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A total of 394 strains of staphylococci found in humans and pets in Novosibirsk, Siberian Russia, were characterized in terms of antibiotic resistance and corresponding genes. Two coagulase-positive and 17 coagulase-negative species were identified. The majority of isolates, with the exception of S. haemolyticus and hospital S. epidermidis isolates, were sensitive to most of the tested antibiotics, and isolates from pets displayed the lowest level of resistance. Nevertheless, methicillin-resistant (MRS) and/or multidrug-resistant (MDR) isolates were found in all prevailed species, including co
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15

Crabb, Charlene. "More sensitive assay to detect drug-resistant HIV." AIDS 21, no. 18 (2007): N3. http://dx.doi.org/10.1097/qad.0b013e3282f20d0c.

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16

Manzano, Alberto, Daniele Musso, and Alvaro Leitao. "Real quantum amplitude estimation." EPJ Quantum Technology, no. 10 (February 3, 2023): 2. https://doi.org/10.1140/epjqt/s40507-023-00159-0.

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We introduce the Real Quantum Amplitude Estimation (RQAE) algorithm, an extension of Quantum Amplitude Estimation (QAE) which is sensitive to the sign of the amplitude. RQAE is an iterative algorithm which offers explicit control over the amplification policy through an adjustable parameter. We provide a rigorous analysis of the RQAE performance and prove that it achieves a quadratic speedup, modulo logarithmic corrections, with respect to unamplified sampling. Besides, we corroborate the theoretical analysis with a set of numerical experiments.
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17

Molina-García, Lucía, M. Luisa Fernández-de Córdova, and Antonio Ruiz-Medina. "Sensitive Determination of Indomethacin in Pharmaceuticals and Urine by Sequential Injection Analysis and Optosensing." Journal of AOAC INTERNATIONAL 93, no. 5 (2010): 1443–49. http://dx.doi.org/10.1093/jaoac/93.5.1443.

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Abstract A selective and sensitive method based on coupling of sequential injection analysis (SIA) and optosensing was developed and applied to the determination of indomethacin in pharmaceutical and urinary samples. After alkaline hydrolysis, the fluorescent product generated from indomethacin is inserted in the flow system, transitorily retained on an active solid support (Sephadex QAE A-25) filling the flowcell, and monitored at 283/371 nm (λex/λem). The system was calibrated for two sample volumes, 100 and 1000 µL. It showed a linear dynamic range of 0.56.5 ng/mL, with an LOD of 0.15 ng/mL
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18

Nash, Denis, Yussef Bennani, Chitra Ramaswamy, and Lucia Torian. "Estimates of HIV Incidence Among Persons Testing for HIV Using the Sensitive/Less Sensitive Enzyme Immunoassy, New York City, 2001." JAIDS Journal of Acquired Immune Deficiency Syndromes 39, no. 1 (2005): 102–11. http://dx.doi.org/10.1097/01.qai.0000144446.52141.4c.

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19

Williams, Emily C., Kathleen A. McGinnis, Janet P. Tate, et al. "HIV Disease Severity Is Sensitive to Temporal Changes in Alcohol Use." JAIDS Journal of Acquired Immune Deficiency Syndromes 81, no. 4 (2019): 448–55. http://dx.doi.org/10.1097/qai.0000000000002049.

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20

Nabatiyan, Arman, Michael A. Baumann, Zaheer Parpia, and David Kelso. "A Lateral Flow-Based Ultra-Sensitive p24 HIV Assay Utilizing Fluorescent Microparticles." JAIDS Journal of Acquired Immune Deficiency Syndromes 53, no. 1 (2010): 55–61. http://dx.doi.org/10.1097/qai.0b013e3181c4b9d5.

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21

Kawamoto, Manabu, Akiko Fujiwara, Shin-ichi Kuno, and Ikuo Yasumasu. "Changes in the activities of protein phosphatase type 1 and type 2A in sea urchin embryos during early development." Zygote 8, S1 (1999): S68—S69. http://dx.doi.org/10.1017/s0967199400130370.

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Serine/threonine protein phosphatases expected to participate in the process of signal transduction, cell movement such as cell division and gene expression (Kinoshita et al., 1990; Healy et al., 1991; Mayer-Jaekel et al., 1993; Mumby & Walter, 1993), are classified into type 1 (PP1), type 2A (PP2A), type 2B and type 2C in mammalian cells. PP1 and PP2A are known to be strongly inhibited by okadaic acid (OA) (Tachibana et al., 1981; Bialojan Takai, 1988), a polyether fatty acid isolated from the marine sponge Halicondria okadai (Haystead et al., 1989). OA is also known to inhibit PP2A at lo
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22

K., Radharavia*1 P.D. Gokulana1 K. L. Senthil Kumara1 R. Ramyaa1 M. Karthik2. "An effective quantitative Gas Chromatography-Head space method development and validation for isopropyl alcohol content in mesalamine prolonged release tablets." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 1419–29. https://doi.org/10.5281/zenodo.11318039.

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This study developed and validated a straightforward, accurate, and sensitive head space-gas chromatography method for measuring the content of isopropyl alcohol in mesalamine prolonged-release tablets. The method uses Agilent Head space-gas chromatography, which has a flame ionization detector, capillary mid-polar stationary phase [DB-624 6% cyanopropyl, 94% polydimethylsiloxane (30 m*0.53 mm, 3µm)] with nitrogen as the carrier gas, and a linear velocity flow rate of 27 ml/min with a 1:5 spilt ratio and an injector temperature of 150 °C. The experiment ran for a total of twelve minu
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K., Radharavi*1 P.D. Gokulan1 K. L. Senthil Kumar1 R. Ramya1 M. Karthik2. "An Effective Quantitative Gas Chromatography-Head Space Method Development And Validation For Isopropyl Alcohol Content In Mesalamine Prolonged Release Tablets." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 1419–29. https://doi.org/10.5281/zenodo.11354677.

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This study developed and validated a straightforward, accurate, and sensitive head space-gas chromatography method for measuring the content of isopropyl alcohol in mesalamine prolonged-release tablets. The method uses Agilent Head space-gas chromatography, which has a flame ionization detector, capillary mid-polar stationary phase [DB-624 6% cyanopropyl, 94% polydimethylsiloxane (30 m*0.53 mm, 3µm)] with nitrogen as the carrier gas, and a linear velocity flow rate of 27 ml/min with a 1:5 spilt ratio and an injector temperature of 150 °C. The experiment ran for a total of twelve minu
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24

Umeki, T., O. Tadanaga, M. Asobe, Y. Miyamoto, and H. Takenouchi. "First demonstration of high-order QAM signal amplification in PPLN-based phase sensitive amplifier." Optics Express 22, no. 3 (2014): 2473. http://dx.doi.org/10.1364/oe.22.002473.

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25

Li, Jin-fen, Laurie Linley, Richard Kline, Rebecca Ziebell, Walid Heneine, and Jeffrey A. Johnson. "Sensitive sentinel mutation screening reveals differential underestimation of transmitted HIV drug resistance among demographic groups." AIDS 30, no. 9 (2016): 1439–45. http://dx.doi.org/10.1097/qad.0000000000001099.

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26

Kikuchi, N., and S. Sasaki. "Highly Sensitive Optical Multilevel Transmission of Arbitrary Quadrature-Amplitude Modulation (QAM) Signals With Direct Detection." Journal of Lightwave Technology 28, no. 1 (2010): 123–30. http://dx.doi.org/10.1109/jlt.2009.2035827.

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27

Allers, Kristina, Stefanie A. Knoepfel, Pia Rauch, et al. "Persistence of Lamivudine-Sensitive HIV-1 Quasispecies in the Presence of Lamivudine In Vitro and In Vivo." JAIDS Journal of Acquired Immune Deficiency Syndromes 44, no. 4 (2007): 377–85. http://dx.doi.org/10.1097/qai.0b013e31803104c0.

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28

Mei, Joanne V., Meredith Kennedy, Laurie Linley, et al. "Standardization and Monitoring of Laboratory Performance and Quality Assurance by Use of the Less-Sensitive HIV Incidence Assay." JAIDS Journal of Acquired Immune Deficiency Syndromes 58, no. 5 (2011): 482–88. http://dx.doi.org/10.1097/qai.0b013e318230dd77.

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29

Abbate, I., G. Rozera, C. Vlassi, et al. "211 Virological Charactrization of HIV-1 Acute Infection by Ultra-Sensitive Next Generation Sequencing." JAIDS Journal of Acquired Immune Deficiency Syndromes 56 (April 2011): 90. http://dx.doi.org/10.1097/01.qai.0000397393.67006.42.

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30

Tang, Shixing, Jiangqin Zhao, James J. Storhoff, et al. "Nanoparticle-Based Biobarcode Amplification Assay (BCA) for Sensitive and Early Detection of Human Immunodeficiency Type 1 Capsid (p24) Antigen." JAIDS Journal of Acquired Immune Deficiency Syndromes 46, no. 2 (2007): 231–37. http://dx.doi.org/10.1097/qai.0b013e31814a554b.

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31

Ellis, Giovanina M., Libby C. Page, Blaire E. Burman, Susan Buskin, and Lisa M. Frenkel. "Increased Detection of HIV-1 Drug Resistance at Time of Diagnosis by Testing Viral DNA With a Sensitive Assay." JAIDS Journal of Acquired Immune Deficiency Syndromes 51, no. 3 (2009): 283–89. http://dx.doi.org/10.1097/qai.0b013e3181a9972c.

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32

Boger, Michael S., Ayumi Shintani, Leigh Anne Redhage, et al. "Highly Sensitive C-Reactive Protein, Body Mass Index, and Serum Lipids in HIV-Infected Persons Receiving Antiretroviral Therapy: A Longitudinal Study." JAIDS Journal of Acquired Immune Deficiency Syndromes 52, no. 4 (2009): 480–87. http://dx.doi.org/10.1097/qai.0b013e3181b939e5.

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33

He, Chunlong, Qigang Jiang, and Peng Wang. "An Improved Physics-Based Dual-Band Model for Satellite-Derived Bathymetry Using SuperDove Imagery." Remote Sensing 16, no. 20 (2024): 3801. http://dx.doi.org/10.3390/rs16203801.

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Shallow water bathymetry is critical for environmental monitoring and maritime security. Current widely used statistical models based on passive optical satellite remote sensing often rely on prior bathymetric data, limiting their application to regions lacking such information. In contrast, the physics-based dual-band log-linear analytical model (P-DLA) can estimate shallow water bathymetry without in situ measurements, offering significant potential. However, the quasi-analytical algorithm (QAA) used in the P-DLA is sensitive to non-ideal pixels, resulting in unstable bathymetry estimation.
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&NA;. "Highly Sensitive C-Reactive Protein, Body Mass Index, and Serum Lipids in HIV-Infected Persons Receiving Antiretroviral Therapy: A Longitudinal Study: Erratum." JAIDS Journal of Acquired Immune Deficiency Syndromes 53, no. 1 (2010): 157. http://dx.doi.org/10.1097/qai.0b013e3181cc804e.

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Wang, Hongxiang, Gen Li, and Yuefeng Ji. "Phase and amplitude regeneration of a rectangular 8-QAM in a phase-sensitive amplifier with low-order harmonics." Applied Optics 56, no. 3 (2017): 506. http://dx.doi.org/10.1364/ao.56.000506.

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Sánchez, Victoria, Mar Masiá, Catalina Robledano, et al. "A Highly Sensitive and Specific Model for Predicting HIV-1 Tropism in Treatment-Experienced Patients Combining Interpretation of V3 Loop Sequences and Clinical Parameters." JAIDS Journal of Acquired Immune Deficiency Syndromes 56, no. 1 (2011): 51–58. http://dx.doi.org/10.1097/qai.0b013e3181fc012b.

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37

James Popham, W., David C. Berliner, Neal M. Kingston, et al. "Can today’s standardized achievement tests yield instructionally useful data?" Quality Assurance in Education 22, no. 4 (2014): 303–18. http://dx.doi.org/10.1108/qae-07-2014-0033.

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Purpose – Against a backdrop of high-stakes assessment policies in the USA, this paper explores the challenges, promises and the “state of the art” with regard to designing standardized achievement tests and educational assessment systems that are instructionally useful. Authors deliberate on the consequences of using inappropriately designed tests, and in particular tests that are insensitive to instruction, for teacher and/or school evaluation purposes. Methodology/approach – The method used is a “moderated policy discussion”. The six invited commentaries represent voices of leading educatio
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38

Wong, Ilene Y., Nicholas V. Lawrence, Helen Struthers, James McIntyre, and Gerald H. Friedland. "Development and Assessment of an Innovative Culturally Sensitive Educational Videotape to Improve Adherence to Highly Active Antiretroviral Therapy in Soweto, South Africa." JAIDS Journal of Acquired Immune Deficiency Syndromes 43, Supplement 1 (2006): S142—S148. http://dx.doi.org/10.1097/01.qai.0000248345.02760.03.

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39

Valdez, Susana. "Using the vignette technique to research health communication in linguistically and culturally discordant settings." Qualitative Health Communication 4, no. 1 (2025): 37–53. https://doi.org/10.7146/qhc.150075.

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Background: The linguistic diversity of today’s societies presents challenges to ensuring that everyone, regardless of their linguistic background, can access and understand health information. The vignette technique offers an approach to exploring these challenges and collecting rich data through contextualized scenarios. Aim: To explore the use of the vignette technique for data collection in linguistically and culturally diverse healthcare settings involving migrants. Methods: To contextualize the vignette technique, the article reviews studies that have employed this method for data collec
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40

Tefferi, A., BA Owen, WL Nichols, TE Witzig, and WG Owen. "Isolation of a heparin-like anticoagulant from the plasma of a patient with metastatic bladder carcinoma." Blood 74, no. 1 (1989): 252–54. http://dx.doi.org/10.1182/blood.v74.1.252.252.

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Abstract A 73-year-old woman with metastatic transitional cell carcinoma of the bladder developed vaginal bleeding a few days after undergoing radical cystectomy. She had no other signs of mucocutaneous bleeding. Coagulation studies revealed a markedly prolonged thrombin time (greater than 600 seconds), a slightly prolonged reptilase time (20 seconds), and mildly elevated fibrinogen (4.39 g/L), and fibrin D-dimer (200 to 500 ng/mL) levels. Treatment of the patient's plasma in vitro with protamine or barium sulfate normalized the thrombin time. The anticoagulant activity corresponded to 0.15 he
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Tefferi, A., BA Owen, WL Nichols, TE Witzig, and WG Owen. "Isolation of a heparin-like anticoagulant from the plasma of a patient with metastatic bladder carcinoma." Blood 74, no. 1 (1989): 252–54. http://dx.doi.org/10.1182/blood.v74.1.252.bloodjournal741252.

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A 73-year-old woman with metastatic transitional cell carcinoma of the bladder developed vaginal bleeding a few days after undergoing radical cystectomy. She had no other signs of mucocutaneous bleeding. Coagulation studies revealed a markedly prolonged thrombin time (greater than 600 seconds), a slightly prolonged reptilase time (20 seconds), and mildly elevated fibrinogen (4.39 g/L), and fibrin D-dimer (200 to 500 ng/mL) levels. Treatment of the patient's plasma in vitro with protamine or barium sulfate normalized the thrombin time. The anticoagulant activity corresponded to 0.15 heparin U/m
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Cui, Jiabin, Guo-Wei Lu, Hongxiang Wang, and Yuefeng Ji. "On-Chip Optical Vector Quadrature De-Multiplexer Proposal for QAM De-Aggregation by Single Bi-Directional SOA-Based Phase-Sensitive Amplifier." IEEE Access 7 (2019): 763–72. http://dx.doi.org/10.1109/access.2018.2885815.

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Kuznetsova, Marina V., Larisa Y. Nesterova, Veronika S. Mihailovskaya, et al. "Nosocomial Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus: Sensitivity to Chlorhexidine-Based Biocides and Prevalence of Efflux Pump Genes." International Journal of Molecular Sciences 26, no. 1 (2025): 355. https://doi.org/10.3390/ijms26010355.

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The widespread use of disinfectants and antiseptics has led to the emergence of nosocomial pathogens that are less sensitive to these agents, which in combination with multidrug resistance (MDR) can pose a significant epidemiologic risk. We investigated the susceptibility of nosocomial Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus to a 0.05% chlorhexidine (CHX) solution and a biocidal S7 composite solution based on CHX (0.07%) and benzalkonium chloride (BAC, 0.055%). The prevalence of efflux pump genes associated with biocide resistance and their re
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Esra, Rachel, Mpho Mmelesi, Akeem T. Ketlogetswe, et al. "Improved Indicators for Subnational Unmet Antiretroviral Therapy Need in the Health System: Updates to the Naomi Model in 2023." JAIDS Journal of Acquired Immune Deficiency Syndromes 95, no. 1S (2024): e24-e33. http://dx.doi.org/10.1097/qai.0000000000003324.

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Background: Quantifying subnational need for antiretroviral therapy (ART) for HIV is challenging because people living with HIV (PLHIV) access health facilities in areas that may differ from their residence. We defined and demonstrated new indicators for PLHIV treatment needed to guide health system target setting and resource allocation. Setting: Botswana. Methods: We extended Naomi, a Bayesian small-area model for estimating district-level HIV indicators from national household survey and HIV service delivery data. We used model outputs for ART seeking probabilities in neighboring districts
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Rajesh Kumar Chawla, Koteswara Rao G S N, Umasankar Kulandaivelu, Siva Prasad Panda, and Rajasekhar Reddy Alavala. "Development and Validation of a Headspace Gas Chromatographic (HS-GC) Method for Determination of Residual Solvents in Nitazoxanide API." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 1719–27. http://dx.doi.org/10.26452/ijrps.v11ispl4.4362.

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Controlling residual solvents in the drug substances or active pharmaceutical ingredients (API) is mandatory to the specified limits as per the International Conference on Harmonisation (ICH) Q3C guidelines. Residual solvents in pharmaceuticals are mostly determined by Gas Chromatography with Headspace. A simple and sensitive headspace gas chromatographic (HS-GC) method has been developed for the determination of Acetone, Dichloromethane and Cyclohexane in Nitazoxanide API. The separation of analytes was achieved with DB – 624 (30 m length, 0.53 mm inner diameter and 3.0 μm in film thickness)
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Glaubius, Robert, John Stover, Leigh F. Johnson, Severin G. Mahiane, Mary I. Mahy, and Jeffrey W. Eaton. "Differences in Breastfeeding Duration by Maternal HIV Status: A Pooled Analysis of Nationally Representative Surveys in Sub-Saharan Africa." JAIDS Journal of Acquired Immune Deficiency Syndromes 95, no. 1S (2024): e81-e88. http://dx.doi.org/10.1097/qai.0000000000003317.

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Background: Breastfeeding improves child survival but is a source of mother-to-child HIV transmission among women with unsuppressed HIV infection. Estimated HIV incidence in children is sensitive to breastfeeding duration among mothers living with HIV (MLHIV). Breastfeeding duration may vary according to maternal HIV status. Setting: Sub-Saharan Africa. Methods: We analyzed pooled data from nationally representative household surveys conducted during 2003–2019 that included HIV testing and elicited breastfeeding practices. We fitted survival models of breastfeeding duration by country, year, a
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Lua, Lu, Pei Tong, Xiaowen Yub, et al. "ST103 HIV-1 variants with mutations in the gp41 pocket region are resistant to HIV fusion inhibitors with pocket-binding domain, but sensitive to T20." JAIDS Journal of Acquired Immune Deficiency Syndromes 62 (April 2013): S65. http://dx.doi.org/10.1097/01.qai.0000429264.98091.c5.

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Stevens, Oliver, Rebecca Anderson, John Stover, et al. "Comparison of Empirically Derived and Model-Based Estimates of Key Population HIV Incidence and the Distribution of New Infections by Population Group in Sub-Saharan Africa." JAIDS Journal of Acquired Immune Deficiency Syndromes 95, no. 1S (2024): e46-e58. http://dx.doi.org/10.1097/qai.0000000000003321.

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Background: The distribution of new HIV infections among key populations, including female sex workers (FSWs), gay men and other men who have sex with men (MSM), and people who inject drugs (PWID) are essential information to guide an HIV response, but data are limited in sub-Saharan Africa (SSA). We analyzed empirically derived and mathematical model-based estimates of HIV incidence among key populations and compared with the Joint United Nations Programme on HIV/AIDS (UNAIDS) estimates. Methods: We estimated HIV incidence among FSW and MSM in SSA by combining meta-analyses of empirical key p
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Omekudo, Oviemuno, Emmanuel Ikpefan, and Felix Enwa. "Antimicrobial and antioxidant studies of the methanolic extract of Cnestis ferruginea DC (connaraceae) leaves." Journal of Current Biomedical Research 2, no. 6, November-December (2022): 683–96. http://dx.doi.org/10.54117/jcbr.v2i6.9.

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Extract from Cnestis ferruginea leaves has been used worldwide due to its antimicrobial and antioxidant activities in treating related ailments. The aim of this study is to investigate the antimicrobial and antioxidant studies of the extract of Cnestis ferruginea DC (Connaraceae) leaves. The methanol extract was evaluated for the presence of phytochemicals. The methanol extract was evaluated for antimicrobial activities against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, Candida albicans, and Aspergillus spp. Thereafter, antioxidant activities were also
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PIACENZA, L., R. RADI, F. GOÑI, and C. CARMONA. "CuZn superoxide dismutase activities from Fasciola hepatica." Parasitology 117, no. 6 (1998): 555–62. http://dx.doi.org/10.1017/s0031182098003394.

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The levels of superoxide dismutase (SOD) were determined in detergent-soluble, somatic and excretion–secretion (E–S) preparations from adult Fasciola hepatica using the xanthine oxidase system and visualized in substrate gels. Compared to detergent-soluble and somatic extracts, E–S products showed the highest SOD activity (88 ·5 U/mg), indicating active release to the medium in which parasites were maintained. SOD specific activity was also detected at high levels in E–S products from 3-week-old and 5-week-old immature migrating flukes (25 and 143 U/mg, respectively). In all preparations excep
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