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Dissertations / Theses on the topic 'Separation of the diastereomers'

Author: Grafiati

Published: 24 April 2022

Last updated: 30 July 2025

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1

Sistla, Venkata Subbarayudu [Verfasser], and Andreas [Akademischer Betreuer] Seidel-Morgenstern. "Formation and crystallization based separation of diastereomeric salts / Venkata Subbarayudu Sistla. Betreuer: Andreas Seidel-Morgenstern." Magdeburg : Universitätsbibliothek, 2012. http://d-nb.info/1053914121/34.

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2

Coss, Clifford Scott. "Minimally Competent Lewis Acid Catalysts. General Methods for the Synthesis and Separation of Diastereomeric Mixtures of Monorhamnolipids of Pseudomonas aeruginosa with Peracetate Glycoside Donors." Diss., The University of Arizona, 2012. http://hdl.handle.net/10150/238915.

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Rhamnolipids are rhamnose-based glycolipids with strong biosurfactant properties. Because they are naturally occurring surfactants found in Gram-negative bacterial walls, rhamnolipids are biodegradable, low in toxicity and have the potential for bioremediation. However, rhamnolipids are biosynthesized as a large mixture of congeners, making purification poor and scalability difficult. The "green" properties of the compound make it a highly desirable alternative for the many carcinogenic and toxic synthetic surfactants on the market. A method for synthesizing rhamnolipids cost-effectively and a

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3

Kämmler, Lena [Verfasser], and Martin [Akademischer Betreuer] Maier. "Totalsynthese von Biselyngbyolid B und dessen (21Z)-Diastereomers, sowie Studien zur Totalsynthese von Biselyngbyasid / Lena Kämmler ; Betreuer: Martin Maier." Tübingen : Universitätsbibliothek Tübingen, 2018. http://d-nb.info/1196701261/34.

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4

Stensils, Elin. "Separation." Thesis, KTH, Arkitektur, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-168616.

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Separation Mitt projekt rör sig kring temat separation, separation av funktioner, separation i fysisk bemärkelse och separation av människor. Jag spenderade mycket tid åt att undersöka kreamtoriet som anläggning, dess programdelar och platsen som vi fått till förfogande. Hela tiden rörde sig undersökningen tillbaka till separation, krematoriets funktionsseparering, åtskillnaden av industri och ceremoni. Jag valde att använda detta som en språngbräda för projektet. Krematoriet är som byggnad tydligt indelad i olika funktioner som försöker distansiera sig från varandra, den industriella och den

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5

Klüppel, André [Verfasser], Martin [Akademischer Betreuer] Hiersemann, and Norbert [Gutachter] Krause. "Ex-chiral-pool-Synthese des (11R,13S,14R,15R)-Diastereomers von (‒)-Lytophilippin A / André Klüppel ; Gutachter: Norbert Krause ; Betreuer: Martin Hiersemann." Dortmund : Universitätsbibliothek Dortmund, 2019. http://d-nb.info/1189420368/34.

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6

Ahmed, A. "Signal separation." Thesis, University of Cambridge, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.595390.

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The problem of signal separation is a very broad and fundamental one. A powerful paradigm within which signal separation can be achieved is the assumption that the signals/sources are statistically independent of one another. This is known as Independent Component Analysis , (ICA). In this thesis, the theoretical aspects and derivation of ICA are examined, from which disparate approaches to signal separation are drawn together in a unifying framework. This is followed by a review of signal separation techniques based on ICA. Second order statistics based output decorrelation methods are employ

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7

Strid, Matilda. "Does Play Pre-separation Affect Separation Behaviors in Dogs?" Thesis, Linköpings universitet, Biologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-148212.

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Separation anxiety is one of the most common behavioral disorder in companion dogs. Dogs not suffering from separation anxiety may still exhibit separation-related behaviors, which can differ depending on environmental contexts. In the present study, dogs without separation-related problems were video recorded during a short separation (3 min) from, and during reunion with, their owner. Comparison was done between if the dogs had played or been calm pre-separation. The dogs spent most time in proximity to the entrance and gazing towards where the owner left during separation. Their body-positi

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8

Bhattacharjee, Samita. "Prediction Of Separation Factor In Foam Separation Of Proteins." Thesis, Indian Institute of Science, 1994. https://etd.iisc.ac.in/handle/2005/132.

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Polyhedral foams offer large gas-liquid interfacial area associated with a small amount of liquid. Therefore, if a solute adsorbs preferentially at the interface, the concentration of the solute in the foam will be greater than in the solution from which the foam has been generated. This effect provides a simple method of concentrating materials which have a tendency to adsorb on the gas-liquid interface. This is particularly relevant to biomaterials like whole cells, proteins, enzymes etc., which are surface active and are present in low concentrations in the broth. Foam separation has theref

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9

Bhattacharjee, Samita. "Prediction Of Separation Factor In Foam Separation Of Proteins." Thesis, Indian Institute of Science, 1994. http://hdl.handle.net/2005/132.

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Polyhedral foams offer large gas-liquid interfacial area associated with a small amount of liquid. Therefore, if a solute adsorbs preferentially at the interface, the concentration of the solute in the foam will be greater than in the solution from which the foam has been generated. This effect provides a simple method of concentrating materials which have a tendency to adsorb on the gas-liquid interface. This is particularly relevant to biomaterials like whole cells, proteins, enzymes etc., which are surface active and are present in low concentrations in the broth. Foam separation has theref

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10

Hoettges, Kai F. "Miniaturisation in separation science : liquid-liquid separation on a chip." Thesis, University of Surrey, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252454.

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11

Wenger, Rephael. "Stabbing and separation." Thesis, McGill University, 1988. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74054.

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12

Chan, D. C. B. "Blind signal separation." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597415.

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The separation of independent sources from mixed observed data is a fundamental and challenging signal processing problem. In many practical situations, one or more desired signals need to be recovered from the mixtures only. A typical example is speech recordings made in an acoustic environment in the presence of background noise and/or competing speakers. Other examples include EEG signals, passive sonar applications and cross-talk in data communications. The audio signal separation problem is sometimes referred to as <I>The Cocktail Party Problem</I>. When several people in the same room ar

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13

Wright, Adam. "Structural separation logic." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/17838.

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This thesis presents structural separation logic, a novel program reasoning approach for software that manipulates both standard heaps and structured data such as lists and trees. Structural separation logic builds upon existing work in both separation logic and context logic. It considers data abstractly, much as it is exposed by library interfaces, ignoring implementation details. We provide a programming language that works over structural heaps, which are similar to standard heaps but allow data to be stored in an abstract form. We introduce abstract heaps, which extend structural heaps to

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14

COUDE, DU FORESTO DE CASTELLAN ANNE. "Separation a l'adolescence." Lille 2, 1989. http://www.theses.fr/1989LIL2M383.

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15

Ziemski, Marcin. "Modelling HTR separation /." St. Lucia, Qld, 2002. http://adt.library.uq.edu.au/public/adt-QU20030902.124611/index.html.

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16

Yusoff, Mohd Suria Affandi. "Separation of olein - stearin from palm oil by crystallization and separation." Thesis, University of Manchester, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390292.

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17

Källdahl, Malin. "Separation Analysis with OpenModelica." Thesis, Linköping University, Department of Electrical Engineering, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-10399.

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<p>When launching a satellite a separation system is used to keep the satellite attached to a launch vehicle during ascent and to separate it from the launch vehicle while in space. In separation analysis the separation is studied by simulations to see if requirements on the system can be fulfilled. The purpose of this master’s thesis is to investigate if separation analysis can be done using the modeling program OpenModelica and to evaluate OpenModelica and compare it to other modeling programs.</p><p>OpenModelica is free software implementing the Modelica language, which is an object-oriente

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18

Al-Mosawi, Masar. "Optimal separation of points." Thesis, KTH, Optimeringslära och systemteori, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-103082.

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How should n points be distributed in a given region F in R^d such that they are separated as much as possible? This general problem is studied in this paper, for some combinations of F, d, n, and the ways one can state the problem mathematically. Some numerical optimization methods are suggested and tested, both on the point separation problem and the closely related circle packing problem. The results are compared with some known analytical results. The main conclusion is that the suggested numerical methods are useful general tools to obtain optimal solutions to the considered problems.

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19

Nassara, Ramiel. "Adsorption separation of ethyleneethane." Thesis, University of Ottawa (Canada), 2008. http://hdl.handle.net/10393/27721.

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To offset rising energy costs, it is becoming a necessity to lower energy usage within industrial processes. Such can be said for the separation of olefin/paraffin mixtures. An example of such a mixture is ethylene/ethane. This highly energy intensive industrial separation employs cryogenic distillation to achieve a high purity product. Subsequently, the energy cost to run such a system is extremely high. Hybrid scenarios have been explored, with adsorption being a potential candidate. This work studied the potential of three adsorbents for the separation of ethylene/ethane: AgNO3/SiO2, CuCl/S

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20

Vogelaar, Laura. "Phase separation micro molding." Enschede : University of Twente [Host], 2005. http://doc.utwente.nl/57840.

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21

Ladanowski, Caroline. "Separation with reverse-micelles." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=60587.

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Reverse-micelles are surfactant aggregates in an apolar solvent. The surfactants, which must have two hydrophobic tails, cluster around a water core. The effects of the compositions of the solvent and the aqueous phase on water solubilization were studied for two anionic surfactants: sodium di-2-ethylhexylsulfosuccinate (AOT) and dinonylnaphthalene sulfonic acid (DNNSA). Single straight chain alkanes having 6-17 carbons, mixtures of these alkanes and branched alkanes were used as solvents. The aqueous phases consisted of salts and buffers.<br>For AOT in straight chain alkanes, water uptake inc

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22

Houle, Michael E. "Weak separation of sets." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74229.

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Consider the following fundamental problem: given two sets R and G of objects positioned in d-dimensional Euclidean space, does there exist a surface of some specific type which separates the objects of R from the objects of G?<br>Much attention has been given to this problem, for many classes of objects and separating surfaces. However, very few satisfactory alternatives exist when the objects are not separable by any of the surfaces of the chosen class. In this thesis, a new combinatorial measure of separability is proposed, based on the largest subset of the objects in $R cup G$ that may be

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23

Deghani, Ali. "Shape separation by screening." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395671.

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24

Wang, Beiming. "Musical audio stream separation." Thesis, Queen Mary, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511337.

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25

Kirstein, Sara N. "MEDICAL SEPARATION AMONG CAREERISTS." Monterey, California. Naval Postgraduate School, 2013. http://hdl.handle.net/10945/32850.

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The last 10 years have presented the Marine Corps with the challenge of continuous deployments to hostile environments at an unprecedented rate. This study examines the correlation between deployment tempo and medical separation rates for Marines who have shown an intention to remain in the Service by reenlisting past their first term. It does so by comparing the probability of medical separation for careerists relative to other causes of separation. The data comes from the Marine Corps Total Data Force Warehouse. Interaction effects were measured using a Linear Probability Model and probit es

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26

Coughlin, Devin. "Type-Intertwined Separation Logic." Thesis, University of Colorado at Boulder, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3704668.

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<p>Static program analysis can improve programmer productivity and software reliability by definitively ruling out entire classes of programmer mistakes. For mainstream imperative languages such as C, C++, and Java, static analysis about the heap---memory that is dynamically allocated at run time---is particularly challenging because heap memory acts as global, mutable state. This dissertation describes how to soundly combine two static analyses that each take vastly different approaches to reasoning about the heap: type systems and separation logic. Traditional type systems take an alias-agno

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27

Hansen, Darcy Michael. "Store separation methodology analysis." Thesis, Monterey, California. Naval Postgraduate School, 1991. http://hdl.handle.net/10945/26790.

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28

Battrum, M. J. "Gas separation by adsorption." Thesis, University of Bath, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376289.

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29

Li, Kang. "Gas separation using membranes." Thesis, University of Salford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292882.

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30

Li, Zhengnan. "Vortex magnetic separation (VMS)." Thesis, University of Southampton, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292447.

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31

Pengilley, Christine. "Membranes for gas separation." Thesis, University of Bath, 2016. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678858.

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The effective separation of ammonia from the synthesis loop in ammonia synthesis plants is an important step in its manufacture. This work presents the use of nanocomposite MFI zeolite membranes prepared by a pore-plugging method for this separation process. Performance of a zeolite membrane is highly dependent on the operating conditions. Therefore, the influences of differential pressure, temperature, sweep gas flow, feed gas flow and gas composition are studied experimentally. Transport of NH3 in this membrane is by surface diffusion in the intracrystalline (zeolite) pores in parallel with

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32

Sagar, Ambuj Daya. "Materials separation by dielectrophoresis." Thesis, Massachusetts Institute of Technology, 1989. http://hdl.handle.net/1721.1/14215.

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33

Nieuwoudt, Traute. "The separation of alcohols." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/53172.

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Thesis (MScEng)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: Pure primary alcohols are very valuable as raw materials and solvents. Close-boiling alcohol mixtures are produced as byproducts from the Fischer Tropsch synthesis. These byproducts include the mixtures 1-butanol+2- penta noI and 1-pentanol+2-hexanol. Due to the small difference in boiling points these alcohols cannot be separated from one another by using conventional distillation. This study has been undertaken to determine whether primary and secondary alcohols may be separated by exploitation of their chemical prop

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34

Emmott, John David. "Chromatographic separation of metals." Thesis, University of Central Lancashire, 2016. http://clok.uclan.ac.uk/16599/.

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In nuclear reprocessing, PUREX, a solvent extraction process, has long been the separation method employed for the separation of the bulk components of irradiated nuclear fuel (namely uranium and plutonium) from the fission products and other minor actinides produced during the fuel use. The uranium and plutonium constitutes approximately 96 % by mass of the irradiated fuel and for this to be removed, requires large volumes of extractant and equipment with large surface area contactors and therefore floor space requirements. The PUREX process has for nearly 60 years been the largely unchalleng

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35

Li, Yipeng. "Monaural Musical Sound Separation." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1211994188.

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36

Khan, Faheem. "Audio-visual speaker separation." Thesis, University of East Anglia, 2016. https://ueaeprints.uea.ac.uk/59679/.

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Communication using speech is often an audio-visual experience. Listeners hear what is being uttered by speakers and also see the corresponding facial movements and other gestures. This thesis is an attempt to exploit this bimodal (audio-visual) nature of speech for speaker separation. In addition to the audio speech features, visual speech features are used to achieve the task of speaker separation. An analysis of the correlation between audio and visual speech features is carried out first. This correlation between audio and visual features is then used in the estimation of clean audio featu

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37

El, Filali Hassna. "Locator id separation protocol." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amslaurea.unibo.it/6198/.

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38

Becker, Saskia. "The Propagation-Separation Approach." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II, 2014. http://dx.doi.org/10.18452/16960.

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Lokal parametrische Modelle werden häufig im Kontext der nichtparametrischen Schätzung verwendet. Bei einer punktweisen Schätzung der Zielfunktion können die parametrischen Umgebungen mithilfe von Gewichten beschrieben werden, die entweder von den Designpunkten oder (zusätzlich) von den Beobachtungen abhängen. Der Vergleich von verrauschten Beobachtungen in einzelnen Punkten leidet allerdings unter einem Mangel an Robustheit. Der Propagations-Separations-Ansatz von Polzehl und Spokoiny [2006] verwendet daher einen Multiskalen-Ansatz mit iterativ aktualisierten Gewichten. Wir präsentieren hier

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39

Donnelly, Joan. "Military separation : effects and mitigating factors : a mixed methods study : does separation relate to retention? : how does acceptance of separation develop?" Thesis, University of East London, 2011. http://roar.uel.ac.uk/3723/.

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Increasing operational commitments mean that military personnel are often separated from their family. Two main concerns arise: what is the impact on the serving person and family? Does increased time away from home affect retention in the Services? A review of relevant literature shows that much of the research to date has treated these as separate outcomes. Several possible research designs are considered. A pragmatist position, asserting that the research question is of primary importance in the choice of methods, is adopted. The design used is a sequential (two phase) explanatory design: q

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40

Augustsson, Jenny, and Emma Nelsson. "Föräldrars separation under småbarnsfasen : en studie om BVC-sjuksköterskors uppfattningom prevention av separation." Thesis, Linköpings universitet, Institutionen för klinisk och experimentell medicin, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-160322.

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Syftet med denna studie är att undersöka BVC:s möjligheter att förebygga de separationer som sker till följd av omställningen från att vara ett par till att även bli förälder. I studien beskrivs BHV-sjuksköterskors uppfattning om prevention av separation under småbarnsfasen samt hur BHV-sjuksköterskor ser på sina förutsättningar att arbeta med föräldrars parrelation. Studien är en kvantitativ enkätstudie. Enkäten har besvarats av BHV-sjuksköterskor anställda i Region Östergötland eller privata utförare med Region Östergötland-avtal. Totalt delades 99 enkäter ut. Svarsfrekvensen var 83 %. Resul

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Hemleben, John Frederick, Benjamin J. Roberts, and Ronald A. Weitzman. "USMC voluntary separation incentive and special separation benefit: who's leaving? : a focus on quality." Thesis, Monterey, California: Naval Postgraduate School, 1993. http://hdl.handle.net/10945/24248.

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42

Nurra, Claudia. "Separation processes in microalgae biorefining." Doctoral thesis, Universitat Rovira i Virgili, 2014. http://hdl.handle.net/10803/403367.

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Aquesta tesi se centra en el desenvolupament de nous enfocaments per a processos de separació en la producció de biodièsel a partir de microalgues mitjançant tecnologia de membranes. Entre totes les etapes implicades en el procés, aquesta tesi se centra en la investigació de la deshidratació de microalgues mitjançant l'ús de diverses tècniques de filtració de membrana i en la transesterificació mitjançant l'ús d'un reactor catalític de membrana. L'etapa de collita és una de les principals responsables del cost final del biodièsel de microalgues, i la reacció de transesterificació necessita la

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43

Pejkovic, Tomislav. "Polynomial root separation and applications." Phd thesis, Universit�� de Strasbourg, 2012. http://tel.archives-ouvertes.fr/tel-00731080.

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We study bounds on the distances of roots of integer polynomials and applications of such results. The separation of complex roots for reducible monic integer polynomials of fourth degree is thoroughly explained. Lemmas on roots of polynomials in the p-adic setting are proved. Explicit families of polynomials of general degree as well as families in some classes of quadratic and cubic polynomials with very good separation of roots in the same setting are exhibited. The second part of the thesis is concerned with results on p-adic versions of Mahler's and Koksma's functions wn and w*n and the r

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44

Newton, Elizabeth Lynn. "Sustainable Reaction and Separation Systems." Thesis, Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/7463.

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With increasing environmental awareness and natural resource limitations, researchers must begin to incorporate sustainability into their process and product designs. One target for green engineering is in reaction and separation design. This is typically done in a wasteful and often toxic manner with organic solvents and lack of recycle. The following thesis discusses alternatives to these costly separations by means of ionic liquids, benign extraction, separation with carbon dioxide, and near critical water. Ionic liquids are combined with carbon dioxide to induce melting point depressio

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45

Li, Yanhong. "Phase separation in giant vesicles." Phd thesis, Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2009/2913/.

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Giant vesicles may contain several spatial compartments formed by phase separation within their enclosed aqueous solution. This phenomenon might be related to molecular crowding, fractionation and protein sorting in cells. To elucidate this process we used two chemically dissimilar polymers, polyethylene glycol (PEG) and dextran, encapsulated in giant vesicles. The dynamics of the phase separation of this polymer solution enclosed in vesicles is studied by concentration quench, i.e. exposing the vesicles to hypertonic solutions. The excess membrane area, produced by dehydration, can either for

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46

Davies, Clair. "Capillary Electrophoretic Separation of Sulfoxides." TopSCHOLAR®, 1998. http://digitalcommons.wku.edu/theses/338.

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Chiral sulfoxides are most widely used in asymmetric synthesis. Their application as chiral synthons has now become a well-established and reliable strategy, mainly due to availability and high asymmetric induction exerted by the chiral sulfinyl group. Very few articles have been published on the separation of chiral sulfoxides; most involve HPLC or GC. The first separation of optically active sulfoxides was described by Phillips and co-workers. To date no work has been reported using capillary electrophoresis for the separation of alkylaryl sulfoxides. A series of alkylaryl sulfoxides were s

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47

Barkey, Wolf Frederik Dirk. "Swept and unswept separation bubbles." Thesis, University of Cambridge, 1987. https://www.repository.cam.ac.uk/handle/1810/250906.

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The effect of sweep on separation bubbles as occurring in the subsonic flows past thin flat plates with rectangular leading edges has been studied experimentally. The distance between separation and reattachment, at high Reynolds number, was about 5.5 times the plate thickness in the flow region undisturbed by end effects. This distance was independent of sweepback for sweep angles up to and including 45<SUP>o</SUP>. The chordwise distribution of a static-pressure coefficient and a coefficient of the intensity of the static-pressure fluctuations, both measured on the surface of the plate and b

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48

Joakim, Valberg. "Document Separation in Digital Mailrooms." Thesis, Linköpings universitet, Artificiell intelligens och integrerad datorsystem, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-122406.

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The growing mail volumes for businesses worldwide is one reason why theyare increasingly turning to digital mailrooms. A digital mailroom automaticallymanages the incoming mails, and a vital technology to its success isdocument classication. A problem with digital mailrooms and the documentclassication is separating the input stream of pages into documents.This thesis investigates existing classication theory and applies it to createan algorithm which solves the document separation problem. This algorithmis evaluated and compared against an existing algorithmic solution, over adataset containi

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Sweeper, Susie, and n/a. "Adult Adjustment to Relationship Separation." Griffith University. School of Applied Psychology, 2004. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20041012.112619.

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Relationship separation is prevalent in Western society and ongoing problems for adults and children are common, resulting in high personal and social costs. A literature review revealed that no existing measure of separation adjustment assessed multiple domains of separation adjustment, and was psychometrically sound. Additionally, a literature review revealed that few studies have investigated change in separation adjustment over time using cognitive predictors. This thesis is a program of research investigating separation adjustment in recently separated adults. Five studies were conducted

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50

Gunawan, David Oon Tao Electrical Engineering &amp Telecommunications Faculty of Engineering UNSW. "Musical instrument sound source separation." Awarded By:University of New South Wales. Electrical Engineering & Telecommunications, 2009. http://handle.unsw.edu.au/1959.4/41751.

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The structured arrangement of sounds in musical pieces, results in the unique creation of complex acoustic mixtures. The analysis of these mixtures, with the objective of estimating the individual sounds which constitute them, is known as musical instrument sound source separation, and has applications in audio coding, audio restoration, music production, music information retrieval and music education. This thesis principally addresses the issues related to the separation of harmonic musical instrument sound sources in single-channel mixtures. The contributions presented in this work include

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