Academic literature on the topic 'Sepsis-Score'

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Journal articles on the topic "Sepsis-Score"

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Osborn, Tiffany M., Gary Phillips, Stanley Lemeshow, et al. "Sepsis Severity Score." Critical Care Medicine 42, no. 9 (2014): 1969–76. http://dx.doi.org/10.1097/ccm.0000000000000416.

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Albright, C. M., T. N. Ali, V. Lopes, D. J. Rouse, and B. L. Anderson. "The Sepsis in Obstetrics Score." Obstetric Anesthesia Digest 35, no. 3 (2015): 142–43. http://dx.doi.org/10.1097/01.aoa.0000469477.57600.9b.

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Krishnamurthy, Vani, Deepti Thandaveshwar, and Srinivasa Murthy Doreswamy. "Modified hematological sepsis score in early diagnosis of neonatal sepsis." International Journal of Research in Medical Sciences 5, no. 8 (2017): 3573. http://dx.doi.org/10.18203/2320-6012.ijrms20173565.

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Background: Diagnosis of neonatal sepsis at an early stage substantially reduces the mortality. The clinician often relies on laboratory parameters to support the clinical suspicion. As blood culture takes time and yield is low, hematological and biochemical parameters often guide to the diagnosis and management. Rodwell’s Hematological sepsis score (HSS) has a reasonable sensitivity but low specificity. Some of the parameters included in that scoring system are repetitive of same pathogenic mechanism. A modified HSS was developed by the authors by removing the repetitive parameters, increasin
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Phillips, Gary S., Tiffany M. Osborn, Kathleen M. Terry, Foster Gesten, Mitchell M. Levy, and Stanley Lemeshow. "The New York Sepsis Severity Score." Critical Care Medicine 46, no. 5 (2018): 674–83. http://dx.doi.org/10.1097/ccm.0000000000002824.

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Reist, K., O. Hilfiker, M. Stepniewski, et al. "Sepsis-Score in der operativen Intensivmedizin." AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie 31, no. 09 (1996): 556–62. http://dx.doi.org/10.1055/s-2007-995984.

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Bohnen, John M. A. "APACHE II Score and Abdominal Sepsis." Archives of Surgery 123, no. 2 (1988): 225. http://dx.doi.org/10.1001/archsurg.1988.01400260113014.

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SCHEIN, MOSHE. "APACHE II Score in Abdominal Sepsis." Archives of Surgery 123, no. 10 (1988): 1288. http://dx.doi.org/10.1001/archsurg.1988.01400340114026.

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Sathaporn, Natthaka, and Bodin Khwannimit. "Validation the performance of New York Sepsis Severity Score compared with Sepsis Severity Score in predicting hospital mortality among sepsis patients." Journal of Critical Care 53 (October 2019): 155–61. http://dx.doi.org/10.1016/j.jcrc.2019.06.017.

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Iskandar, Agustin, and Fran Siska. "Analisis Hubungan Sequential Organ Failure Assessment (Sofa) Score Dengan Mortalitas Pasien Sepsis." Jurnal Kesehatan Andalas 9, no. 2 (2020): 168. http://dx.doi.org/10.25077/jka.v9i2.1221.

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Sepsis merupakan kondisi disfungsi organ mengancam nyawa yang diakibatkan oleh disregulasi sistem imun pejamu terhadap infeksi dan Sequential Organ Failure Assessment (SOFA) score merupakan suatu skoring untuk menilai kegagalan organ terkait sepsis. Peningkatan SOFA score diasosiasikan dengan outcome pasien yang lebih buruk. Tujuan: Menganalisis korelasi SOFA score dengan mortalitas pada pasien sepsis. Metode: Desain penelitian adalah kohort prospektif yang dilakukan di RSU Dr Saiful Anwar dari Maret 2018 hingga Juni 2019. Kriteria diagnosis sepsis ditegakkan berdasarkan The Third Internationa
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Syplyviy, V. A., S. V. Grinchenko, D. V. Ievtushenko, and A. V. Ievtushenko. "Evaluation Scale of Sepsis II severity score." Modern medical technologies 41 part 3, no. 2 (2019): 40–44. http://dx.doi.org/10.34287/mmt.2(41).2019.38.

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Background. Actually sepsis is one of the main causes of high lethality among surgical patients. The purpose of this study. Is improvement of Sepsis severity evaluation Score based on available clinical and laboratory indicators.Materials and methods. 140 patients with surgical sepsis and purulent focuses localized in skin and subcutaneous tissue, abdominal cavity, lung, urogenital system were included to investigation. Results. Improved Sepsis severity evaluation Score includes clinical characteristics (estimation of consciousness, systolic blood pressure, heart rate, respiratory rate, daily
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Dissertations / Theses on the topic "Sepsis-Score"

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Diedrich, Stephan, der Linde Julia van, Michael Nielson, et al. "The MRI Sepsis Score: An Innovative Tool for the Evaluation of Septic Peritonitis in Mice Using 7-Tesla Small Animal MRI." Karger, 2018. https://tud.qucosa.de/id/qucosa%3A38909.

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Background: Magnetic resonance imaging (MRI) techniques are rarely used in the context of abdominal sepsis and in sepsis research. This study investigates the impact of MRI for monitoring septic peritonitis in an animal model (colon ascendens stent-induced peritonitis, CASP). The CASP model closely mimics that of human disease and is highly standardized. The most frequently employed readout parameter in mouse CASP studies is prolonged or decreased rate of survival. Monitoring the progression of peritonitis via MRI could provide a helpful tool in the evaluation of severity. The use of alternati
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Herrera, Hurtado Gianina Liseth del Carmen. "Evaluación del Score SOFA y el Quick SOFA para el diagnóstico de la sepsis en pacientes del Hospital Nacional Daniel Alcides Carrión, 2016." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2017. https://hdl.handle.net/20.500.12672/6011.

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Hinder, Anja [Verfasser]. "Haben SAPS II-, SAPS 3-, APACHE II- und SOFA-Score, sowie Anzahl der Organdysfunktionen, neben der Zeit bis zur Antibiose und Fokussanierung, eine Aussagekraft bezüglich der Mortalität von Patienten mit schwerer Sepsis und septischem Schock? / Anja Hinder." Ulm : Universität Ulm, 2018. http://d-nb.info/1153828510/34.

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Klee, Yvonne. "Bedeutung des primären Infektfokus für die Morbidität und Mortalität bei Patienten mit Sepsis." Doctoral thesis, 2017. http://hdl.handle.net/11858/00-1735-0000-0023-3F42-4.

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Klimpel, Jenny. "Die Auswirkung der Sepsis-3 Definition auf die intensivmedizinische Aufnahme von Patienten mit Infektion." 2020. https://ul.qucosa.de/id/qucosa%3A74098.

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Schaefer, Steffen [Verfasser]. "Arrhythmien und eingeschränkte Herzfrequenzvariabilität bei Patienten mit Score-quantifizierter Sepsis und Score-quantifiziertem MODS : eine prospektive Studie auf einer internistischen Intensivstation / von Steffen Schaefer." 2005. http://d-nb.info/985247355/34.

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Faisal, Muhammad, Andy J. Scally, D. Richardson, et al. "Development and external validation of an automated computer-aided risk score for predicting sepsis in emergency medical admissions using the patient’s first electronically recorded vital signs and blood test results." 2017. http://hdl.handle.net/10454/14800.

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Yes<br>Objectives: To develop a logistic regression model to predict the risk of sepsis following emergency medical admission using the patient’s first, routinely collected, electronically recorded vital signs and blood test results and to validate this novel computer-aided risk of sepsis model, using data from another hospital. Design: Cross-sectional model development and external validation study reporting the C-statistic based on a validated optimized algorithm to identify sepsis and severe sepsis (including septic shock) from administrative hospital databases using International Classi
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Faisal, Muhammad, D. Richardson, Andy J. Scally, et al. "Computer-aided National Early Warning Score to predict the risk of sepsis following emergency medical admission to hospital: a model development and external validation study." 2019. http://hdl.handle.net/10454/17028.

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Yes<br>Background: In English hospitals, the patient’s vital signs are monitored and summarised into a National Early Warning Score (NEWS). NEWS is more accurate than the quick sepsis related organ failure assessment (qSOFA) score at identifying patients with sepsis. We investigate the extent to which the accuracy of the NEWS is enhanced by developing computer-aided NEWS (cNEWS) models. We compared three cNEWS models (M0=NEWS alone; M1=M0 + age + sex; M2=M1 + subcomponents of NEWS + diastolic blood pressure) to predict the risk of sepsis. Methods: All adult emergency medical admissions discha
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Gerber, Sebastian. "Assoziation des PDCD1 rs11568821 GG-Genotyps mit stärkerer Morbidität bei Intensivpatienten mit Krankheitsbild Sepsis: Vergleich der SOFA-Sub-Scores." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0028-878B-B.

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Books on the topic "Sepsis-Score"

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Moaveni, Daria M. Systemic Inflammatory Response Syndrome and Sepsis in the Pregnant Patient. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0047.

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The chapter “Systemic Inflammatory Response Syndrome and Sepsis in the Pregnant Patient” reviews diagnostic criteria for sepsis in pregnant women, as well as the etiology, risk factors, workup, and treatment of this preventable and treatable cause of maternal morbidity and mortality. It also briefly reviews the history and epidemiology of sepsis. It compares the original diagnostic criteria for systemic inflammatory response syndrome established in 1992, the sepsis diagnostic criteria from the Surviving Sepsis Campaign, and the Sepsis in Obstetrics Score. It discusses the initial workup and re
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Adam, Sheila, Sue Osborne, and John Welch. The critical care continuum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199696260.003.0001.

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This chapter provides an overview of the development and expansion of critical care, to include early intervention and enhancement of recovery. This is based on the patient’s acuity and need for intervention rather than their location. It includes early recognition of, and response to, acute deterioration in patients in order to prevent irreversible organ damage or death. The use of tools such as the National Early Warning Score (NEWS) to identify these patients is described. The chapter covers the critical care outreach and medical emergency team concepts, as well as surviving sepsis and avoi
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Book chapters on the topic "Sepsis-Score"

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Mohamad Suhaimi, Fatanah, Ummu Kulthum Jamaludin, Normy Norfiza Abdul Razak, et al. "Blood Glucose and Sepsis Score on Sepsis Patients Requiring Insulin Therapy." In IFMBE Proceedings. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-7554-4_46.

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Marshall, J. C. "Multiple Organ Dysfunction (MOD) Score." In Sepsis and Organ Dysfunction. Springer Milan, 1998. http://dx.doi.org/10.1007/978-88-470-2271-3_4.

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Díaz, Emili, and Thiago Lisboa. "Ventilator-Associated Pneumonia PIRO Score." In Management of Sepsis: The PIRO Approach. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00479-7_4.

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Littlejohn, James E. "Postoperative Septic Shock." In Cardiothoracic Critical Care. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190082482.003.0010.

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This chapter discusses postoperative sepsis, which is a severe systemic inflammatory response to an infection. Sepsis is particularly difficult to diagnose in the early postoperative period because the systemic inflammatory response syndrome (SIRS) from cardiac surgery alone can mimic the early symptoms. Organ dysfunction identified using the Sequential Organ Failure Assessment (SOFA) score has been replacing the SIRS criteria as a more sensitive means by which to identify physiologic effects of infection. Evidence from studies using the SOFA-guided definition supports the use of the Sepsis-3 criteria for early identification and treatment of patients who are at high risk of adverse outcomes from sepsis and septic shock. The chapter also explores the role of biomarkers to expedite diagnosis and management of infections and/or sepsis. Procalcitonin levels are a biomarker that shows promise in predicting bacteremia, as well as lending clinical support to wean antibiotic duration in certain circumstances. The chapter then details the treatment for sepsis and septic shock. The first objective is to identify possible causes of infection and accomplish source control. Once sepsis has been identified, early resuscitation interventions are pivotal to reduce morbidity and mortality.
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Nesaragi, Naimahmed, and Shivnarayan Patidar. "An Explainable Machine Learning Model for Early Prediction of Sepsis Using ICU Data." In Infectious Diseases and Sepsis [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98957.

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Early identification of individuals with sepsis is very useful in assisting clinical triage and decision-making, resulting in early intervention and improved outcomes. This study aims to develop an explainable machine learning model with the clinical interpretability to predict sepsis onset before 6 hours and validate with improved prediction risk power for every time interval since admission to the ICU. The retrospective observational cohort study is carried out using PhysioNet Challenge 2019 ICU data from three distinct hospital systems, viz. A, B, and C. Data from A and B were shared publicly for training and validation while sequestered data from all three cohorts were used for scoring. However, this study is limited only to publicly available training data. Training data contains 15,52,210 patient records of 40,336 ICU patients with up to 40 clinical variables (sourced for each hour of their ICU stay) divided into two datasets, based on hospital systems A and B. The clinical feature exploration and interpretation for early prediction of sepsis is achieved using the proposed framework, viz. the explainable Machine Learning model for Early Prediction of Sepsis (xMLEPS). A total of 85 features comprising the given 40 clinical variables augmented with 10 derived physiological features and 35 time-lag difference features are fed to xMLEPS for the said prediction task of sepsis onset. A ten-fold cross-validation scheme is employed wherein an optimal prediction risk threshold is searched for each of the 10 LightGBM models. These optimum threshold values are later used by the corresponding models to refine the predictive power in terms of utility score for the prediction of labels in each fold. The entire framework is designed via Bayesian optimization and trained with the resultant feature set of 85 features, yielding an average normalized utility score of 0.4214 and area under receiver operating characteristic curve of 0.8591 on publicly available training data. This study establish a practical and explainable sepsis onset prediction model for ICU data using applied ML approach, mainly gradient boosting. The study highlights the clinical significance of physiological inter-relations among the given and proposed clinical signs via feature importance and SHapley Additive exPlanations (SHAP) plots for visualized interpretation.
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Melzer, Mark. "Sepsis—Recognition, Diagnosis, and Management in Adult Patients." In Tutorial Topics in Infection for the Combined Infection Training Programme. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198801740.003.0032.

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Sepsis is defined as life- threatening organ dysfunction caused by a detrimental host response to infection. Septic shock is a subset of sepsis in which underlying circulatory and cellular abnormalities are profound enough to substantially increase mortality. Septic shock is characterized by: ● The need for vasopressors to maintain mean arterial pressure (MAP) &gt; 65mmHg despite adequate volume resuscitation. ● A serum lactate &gt; 2mmol/L In lay terms, it is hypoperfusion with evidence of metabolic derangement. The mortality for both criteria is ~40%, compared to 20–30% for a single item. Please also refer to: https:// www.nice.org.uk/ guidance/indevelopment/gid-cgwave0686 The old definitions of sepsis described a heterogeneous group of patients and did not discriminate between infectious and non- infectious causes such as pancreatitis and trauma. The new definitions also allow easier recognition, based on a combination of symptoms and signs. Key parameters include: decreased level of consciousness, rigors, severe myalgia, high or low temperature, pulse &gt; 130/min, systolic blood pressure &lt; 90mmHg, respiratory rate (RR) &gt; 25/ min, creatinine &gt; 170μmol/ L, platelets &lt; 100 x 109/l and bilirubin &gt; 33μmol/ L. The Clinical Quality Commission recommend that NHS trusts use the national early warning score (NEWS), and a score &gt; 5 is an indication to consider moving a patient to critical care. SIRS is defined as any of the two following criteria: acutely altered mental state, temperature &lt; 36°C or &gt; 38°C, pulse &gt; 90/ min, RR &gt; 20/ min, WCC &gt; 12 or &lt; 4 x 109/L and hyperglycaemia in the absence of diabetes mellitus. In the former definitions (1991 and 2001), sepsis was defined as infection plus SIRS. SIRS, however, was not good at separating infected patients who died from those who recovered from infection. SIRS was often an appropriate reaction to infection and many hospitalized patients meet the SIRS criteria. Also, as many as one in eight patients admitted to critical care units with infection and new organ failure did not have two SIRS criteria required to fulfil the sepsis definition. SIRS is no longer part of the new definitions.
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Fairchild, Karen D., and J. Randall Moorman. "Heart Rate Characteristics Monitoring in the NICU." In Neonatal Monitoring Technologies. IGI Global, 2012. http://dx.doi.org/10.4018/978-1-4666-0975-4.ch008.

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Heart rate variability (HRV), a marker of autonomic nervous system function, is depressed in sepsis and other acute and chronic diseases. Preterm neonates with sepsis have been shown to have both depressed HRV and repetitive transient heart rate decelerations. These abnormal heart rate characteristics (HRC) of depressed variability and decelerations may precede other clinical signs and symptoms of sepsis and usually are not apparent to clinicians using conventional vital signs monitoring. In order to quantitate these changes associated with sepsis, a heart rate characteristics monitor was developed which continuously calculates an HRC index from the conventional electrocardiogram waveform tracing. This HRC index is the fold-increase in risk that a baby will experience a clinical deterioration consistent with proven or clinical sepsis in the next 24 hours. This HRC or HeRO™ (Heart Rate Observation) Monitor can alert clinicians to carefully evaluate a patient and consider antibiotic therapy or other interventions. The impact of continuous HRC monitoring on outcomes of preterm infants was the subject of a multicenter randomized clinical trial of 3003 very low birth weight infants, completed in 2010, which showed a significant reduction in mortality in neonates whose HRC index, or “HeRO Score” was displayed to clinicians in the NICU. Continuous HRC monitoring is an important new tool for both clinical care and research in the NICU.
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Heidbuchel, Hein. "Clinical investigation of patients presenting with atrial fibrillation." In ESC CardioMed. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0502.

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A patient presenting with atrial fibrillation (AF) should trigger a thorough search for underlying contributing causes since treatment of these will contribute to the prevention of new AF recurrences but also to improved morbidity and mortality in general. If the initial presentation with AF is associated with severe symptoms or precipitating factors such as sepsis, hospitalization is required for specialized care. Full initial evaluation of a new AF patient includes a thorough medical history, physical examination, 12-lead electrocardiogram (ECG), transthoracic echocardiography, and laboratory testing, mainly to assess underlying factors and comorbidities. Ancillary investigations such as exercise testing, long-term ECG recording, or advanced cardiac or cerebral imaging may be indicated in some. A further systematic assessment of symptoms (by means of the modified European Heart Rhythm Association score), of thromboembolic risk (with the CHA<sub>2</sub>DS<sub>2</sub>-VASc score), and of modifiable bleeding risk factors (through the HAS-BLED score), will allow the development of an individualized management plan. Patient and other caregiver education on the goals of the different treatment components and on concrete action items (such as weight loss, medication adherence, and reaction in case of recurrent symptoms) forms an integral part of the initial evaluation to ensure successful implementation of the management plan.
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"Haematology and oncology." In Emergencies in Clinical Medicine, edited by Piers Page, Asif Shah, Greg Skinner, Alan Weir, and Natasha Eagles. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198779117.003.0008.

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This chapter contains guidance on the immediate management and treatment of a number of haematological and oncological emergencies, including acute transfusion reactions, acute sickle crisis, neutropenic sepsis, deep vein thrombosis, superior vena cava obstruction, and metastatic spinal cord compression. Concise advice is given on the immediate treatment of each condition, with instructions on which tests and cultures to take, and the conditions in which it is necessary to report to the transfusion laboratory. Helpful guidelines are provided, such as the Wells score for deep vein thrombosis along with a flowchart to track the condition’s development. Further reading is provided at the end of each topic.
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Lubis, I. N. D., D. E. F. Liestiadi, E. Azlin, and S. Nafianti. "Use of C-Reactive Protein (CRP) and haematological score to predict positive blood cultures in sepsis." In Stem Cell Oncology. CRC Press, 2018. http://dx.doi.org/10.1201/9781351190152-17.

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Conference papers on the topic "Sepsis-Score"

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Wu, P. F. "The Association of Sepsis Bundles Adherence and Outcome of Sepsis Patients with High Quick Sequential Organ Failure Assessment (qSOFA) Score." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3512.

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Zahir, M., KK Eneh, P. Sharma, FM Schmidt, and EA Jaffe. "Correlation of Mortality in Emergency Department Sepsis (MEDS) Score and 30 Day In-Hospital Mortality: A Retrospective Analysis." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4726.

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Janks, M., F. Cantle, E. Ryan, and H. Joyce. "G242(P) Does the sepsis screening tool used in the paediatric emergency department highlight children at risk of sepsis and what is the relationship of initial bpews score to patient outcome." In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference–Online, 25 September 2020–13 November 2020. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2020. http://dx.doi.org/10.1136/archdischild-2020-rcpch.209.

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Wang, R., G. Banda-Katha, S. B. Gordon, C. S. Calfee, L. Huang, and J. Rylance. "The Sonographic B-Line Score Is Associated with the Volume of Intravenous Fluid Given to Malawian Patients with Suspected Sepsis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4127.

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Smith, SB, TM Ehle, O. Gajic, and B. Afessa. "The Performance of APACHE III Score in Predicting the Outcome of Patients with Hematologic Malignancy Admitted for Severe Sepsis/Septic Shock." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5839.

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Shitrit, David, David Dahan, Daniel King, Lilach Israeli-Shani, and Gali Epstein Shochet. "Resting Energy Expenditure (REE) level is significantly associated with CRP, WBC and the Sepsis-related Organ Failure Assessment (SOFA) score in ICU septic patients." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2114.

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Jahn, M., J. Rekowski, G. Gerken, A. Kribben, A. Canbay, and A. Katsounas. "Der SAPS 2 Score unterschätzt das Mortalitätsrisiko bei Lebererkrankungen und Sepsis: Ergebnisse einer retrospektiven Studie auf einer gastroenterologisch-hepatologisch-nephrologisch geführten, konservativen 22-Betten Intermediate Care Unit (IMC) an einem Westdeutschen Transplantationszentrum." In Viszeralmedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1695272.

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Giri, Shveta, Swati Shah, Rupinder Sekhon, and Sudhir Rawal. "Clinical outcomes of cytoreductive surgery and HIPEC in advanced and recurrent epithelial ovarian cancers with peritoneal carcinomatosis." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685311.

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Introduction: The role of surgery for Peritoneal carcinomatosis (PC) has slowly evolved from palliation to potential curative intent. Attempting to remove all visible tumor deposits, “surgical cytoreduction” (CRS) was reported in 1930s for ovarian cancer and eventually became an accepted therapy with proven survival benefit. The new approach of combining CRS and Hyperthermic intraperitoneal chemotherapy (HIPEC) to treat peritoneal metastasis offer hope for long term survival in this group of patients. The risk and benefit of this approach continued to be debated. A prospective study was conduc
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Giri, Shveta, Swati Shah, Rupinder Sekhon, and Sudhir Rawal. "Clinical outcomes of cytoreductive surgery and HIPEC in advanced and recurrent epithelial ovarian cancers with peritoneal carcinomatosis." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685300.

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Introduction: The role of surgery for peritoneal carcinomatosis (PC) has slowly evolved from palliation to potential curative intent. Attempting to remove all visible tumor deposits, “surgical cytoreduction” (CRS) was reported in 1930s for ovarian cancer and eventually became an accepted therapy with proven survival benefit. The new approach of combining CRS and hyperthermic intraperitoneal chemotherapy (HIPEC) to treat peritoneal metastasis offer hope for long term survival in this group of patients. The risk and benefit of this approach continued to be debated. A prospective study was conduc
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