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Journal articles on the topic 'Sequential schedule'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Fatchurrochman, Fatchurrochman, Arif Nur Afandi, and M. Zainal Arifin. "Sistem Penjadwalan Perkuliahan Universitas Otomatis Menggunakan Algoritma Sequential Search." Jurnal Inovasi Teknologi dan Edukasi Teknik 2, no. 4 (2022): 170–78. http://dx.doi.org/10.17977/um068v2i42022p170-178.

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University course timetabling is a routine activity that takes a long time to complete. There are many things to consider. This research focuses on solving the problem of lecture scheduling as a system. There are three components in the system that are used to solve lecture scheduling problems in the real world. The first component is used to generate schedules automatically which guarantees that hard constraints will not be violated. The second component is an interactive lecture scheduling component used to improve and enhance the lecture schedule obtained from the first component. This seco

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O'Shaughnessy, JA, DJ Venzon, M. Gossard, et al. "A phase I study of sequential versus concurrent interleukin-3 and granulocyte-macrophage colony-stimulating factor in advanced breast cancer patients treated with FLAC (5-fluorouracil, leucovorin, doxorubicin, cyclophosphamide) chemotherapy." Blood 86, no. 8 (1995): 2913–21. http://dx.doi.org/10.1182/blood.v86.8.2913.2913.

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Abstract Cumulative thrombocytopenia is a dose-limiting toxicity of dose-intensive chemotherapy for advanced breast cancer. In this phase I study, we have studied the hematologic toxicity associated with sequential interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF; molgramostim) administration after multiple cycles of FLAC (5-fluorouracil, leucovorin, doxorubicin, cyclophosphamide) chemotherapy compared with that after concurrent cytokine administration or to each cytokine administered alone. Ninety- three patients with advanced breast cancer were treated with f

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O'Shaughnessy, JA, DJ Venzon, M. Gossard, et al. "A phase I study of sequential versus concurrent interleukin-3 and granulocyte-macrophage colony-stimulating factor in advanced breast cancer patients treated with FLAC (5-fluorouracil, leucovorin, doxorubicin, cyclophosphamide) chemotherapy." Blood 86, no. 8 (1995): 2913–21. http://dx.doi.org/10.1182/blood.v86.8.2913.bloodjournal8682913.

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Cumulative thrombocytopenia is a dose-limiting toxicity of dose-intensive chemotherapy for advanced breast cancer. In this phase I study, we have studied the hematologic toxicity associated with sequential interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF; molgramostim) administration after multiple cycles of FLAC (5-fluorouracil, leucovorin, doxorubicin, cyclophosphamide) chemotherapy compared with that after concurrent cytokine administration or to each cytokine administered alone. Ninety- three patients with advanced breast cancer were treated with five cycle

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Wang, Ziwei, and Ehsan Rezazadeh Azar. "BIM-based draft schedule generation in reinforced concrete-framed buildings." Construction Innovation 19, no. 2 (2019): 280–94. http://dx.doi.org/10.1108/ci-11-2018-0094.

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PurposeProject schedules have a vital role in the effective management of time, cost, scope and resources in construction projects, and creating schedules requires schedulers with construction knowledge and experience. The increase in the complexity of building projects and the emergence of building information modeling (BIM) in the architecture, engineering and construction industry have encouraged researchers to explore BIM capabilities for automated schedule generation. The scope and capabilities of the developed systems, however, are limited and the link between design and scheduling is st

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Velarde Martínez, Apolinar. "Parallelization of Array Method with Hybrid Programming: OpenMP and MPI." Applied Sciences 12, no. 15 (2022): 7706. http://dx.doi.org/10.3390/app12157706.

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For parallelization of applications with high processing times and large amounts of storage in High Performance Computing (HPC) systems, shared memory programming and distributed memory programming have been used; a parallel application is represented by Parallel Task Graphs (PTGs) using Directed Acyclic Graphs (DAGs). For the execution of PTGs in HPC systems, a scheduler is executed in two phases: scheduling and allocation; the execution of the scheduler is considered an NP-complete combinatorial problem and requires large amounts of storage and long processing times. Array Method (AM) is a s

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Othman, Jamal, Naemah Abdul Wahab, Rozita Kadar, and Saiful NizamWarris. "Assigning Examination Invigilator's Schedule Problem: An Approach of Programming Techniques Using Simple Sequential Assignment." Journal of Computing Research and Innovation 2, no. 1 (2018): 1–9. http://dx.doi.org/10.24191/jcrinn.v2i1.17.

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Preparation of examination invigilation schedule is a tedious and challenging tasks. It is impossible to satisfy all invigilators or proctors with the invigilation schedules prepared. The examination committees have to analyze and thoroughly checks all constraints submitted by the invigilators. Formerly, the process of assignments and deciding the best slot for invigilation will usually take a couple of weeks and all these processes are done manually. This paper proposes a programming technique using simple sequential approach to assign the invigilators on the proper examination slot without a

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7

Han, Wen-Jui, and Julia Shu-Huah Wang. "Changing Employment and Work Schedule Patterns over the 30 Working Years—A Sequential Cluster Analysis." International Journal of Environmental Research and Public Health 19, no. 20 (2022): 13677. http://dx.doi.org/10.3390/ijerph192013677.

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Objective. As labor markets have become increasingly volatile and precarious since 1980s, more workers are susceptible to working conditions such as unpredictable and unstable hours, threatening their economic security. However, our understanding of employment patterns regarding the changes in work schedules over our working lives has yet been established. This study builds our knowledge in this area by paying attention to how social positions may shape the specific work schedule patterns over our working lives. Methods. We used the National Longitudinal Survey of Youth-1979 (NLSY79) to examin

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Sobrero, A. F., C. Aschele, and J. R. Bertino. "Fluorouracil in colorectal cancer--a tale of two drugs: implications for biochemical modulation." Journal of Clinical Oncology 15, no. 1 (1997): 368–81. http://dx.doi.org/10.1200/jco.1997.15.1.368.

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PURPOSE To determine if fluorouracil (FUra) has different mechanisms of action as a function of the dose schedule used. DESIGN The preclinical and clinical literature relating toxicity and antitumor effects of FUra as a function of its dose schedule, with and without modulating agents, was reviewed. RESULTS The data support the hypothesis that FUra may be considered to be two different drugs, depending on its dose schedule (bolus v continuous infusion [CI]). CONCLUSION These results suggest that additional therapeutic benefit may be obtained from FUra regimens by (1) appropriate schedule-depen

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Fang, Jiaqi, Hanping Hou, Changxiang Lu, et al. "A new scheduling method based on sequential time windows developed to distribute first-aid medicine for emergency logistics following an earthquake." PLOS ONE 16, no. 2 (2021): e0247566. http://dx.doi.org/10.1371/journal.pone.0247566.

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After an earthquake, affected areas have insufficient medicinal supplies, thereby necessitating substantial distribution of first-aid medicine from other supply centers. To make a proper distribution schedule, we considered the timing of supply and demand. In the present study, a “sequential time window” is used to describe the time to generate of supply and demand and the time of supply delivery. Then, considering the sequential time window, we proposed two multiobjective scheduling models with the consideration of demand uncertainty; two multiobjective stochastic programming models were also

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10

Yackley, Aaron. "Developing Musicianship through Chamber Ensembles: A Sequential Unit Design." Music Educators Journal 108, no. 1 (2021): 34–42. http://dx.doi.org/10.1177/00274321211027628.

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Shifting school schedules, small class sizes, and unpredictable instrumentation resulting from the global pandemic necessitated a creative approach to teaching ensemble music classes this year. In response to that challenge, I constructed a curriculum for developing independent musicianship through chamber music. Part independence, self-evaluation, communication skills, and practice strategies were key focuses during the term. This sequential approach to introducing chamber music can be transferred beyond a “pandemic schedule” with any ensemble regardless of experience level or instrumentation

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Mezentsev, Yu A., Yu L. Korotkova, and I. V. Estraich. "An Efficient Algorithm for Solving the Applied Problem Scheduling Optimization of a Parallel-Sequential System." Informacionnye Tehnologii 27, no. 12 (2021): 642–50. http://dx.doi.org/10.17587/it.27.642-650.

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The problem of optimal regulation of airline fleet schedules by reassigning aircraft to flights is considered. The optimal regulation of schedules is to create or change them in such a way that minimizes system losses due to current violations. As an estimate of losses, the total deviation of the adjusted schedule from the spetified departure schedules of aircraft is used. It is shown that the described technological system belongs to the category of parallel-sequential systems. Accordingly, the considered system control problem is NP-hard and does not have effective algorithms for exact solut

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&NA;. "Sequential docetaxel schedule feasible for metastatic breast cancer." Inpharma Weekly &NA;, no. 1304 (2001): 18. http://dx.doi.org/10.2165/00128413-200113040-00049.

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Liu, Zheng, and Barry J. Richmond. "Response Differences in Monkey TE and Perirhinal Cortex: Stimulus Association Related to Reward Schedules." Journal of Neurophysiology 83, no. 3 (2000): 1677–92. http://dx.doi.org/10.1152/jn.2000.83.3.1677.

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Anatomic and behavioral evidence shows that TE and perirhinal cortices are two directly connected but distinct inferior temporal areas. Despite this distinctness, physiological properties of neurons in these two areas generally have been similar with neurons in both areas showing selectivity for complex visual patterns and showing response modulations related to behavioral context in the sequential delayed match-to-sample (DMS) trials, attention, and stimulus familiarity. Here we identify physiological differences in the neuronal activity of these two areas. We recorded single neurons from are

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Cicirello, Vincent. "Variable Annealing Length and Parallelism in Simulated Annealing." Proceedings of the International Symposium on Combinatorial Search 8, no. 1 (2021): 2–10. http://dx.doi.org/10.1609/socs.v8i1.18424.

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In this paper, we propose: (a) a restart schedule for an adaptive simulated annealer, and (b) parallel simulated annealing, with an adaptive and parameter-free annealing schedule. The foundation of our approach is the Modified Lam annealing schedule, which adaptively controls the temperature parameter to track a theoretically ideal rate of acceptance of neighboring states. A sequential implementation of Modified Lam simulated annealing is almost parameter-free. However, it requires prior knowledge of the annealing length. We eliminate this parameter using restarts, with an exponentially increa

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Horwitz, Steven M., Julie M. Vose, Ranjana Advani, et al. "Pralatrexate and Gemcitabine in Patients with Relapsed or Refractory Lymphoproliferative Malignancies: Phase 1 Results." Blood 114, no. 22 (2009): 1674. http://dx.doi.org/10.1182/blood.v114.22.1674.1674.

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Abstract Abstract 1674 Poster Board I-700 Background Pralatrexate is a new anti-folate with increased affinity for the reduced folate carrier 1 (RFC-1) and longer intracellular retention in tumor cells due to efficient polyglutamation by folylpolyglutamyl synthetase (FPGS). Pralatrexate and gemcitabine each have activity as monotherapy in patients with relapsed or refractory lymphoma. Preclinical data reported synergy for the combination in NHL cell lines and xenografts that was schedule dependent (pralatrexate followed by gemcitabine) (Clin Cancer Res 2006;12:924-932). We initiated a multi-ce

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Yao, Wan X. "Average-Kr Schedule Benefits Generalized Motor Program Learning." Perceptual and Motor Skills 97, no. 1 (2003): 185–91. http://dx.doi.org/10.2466/pms.2003.97.1.185.

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The main purpose of this study was to examine the effects of average Knowledge of Results (KR) on generalized motor program learning and parameter learning. Two groups of participants ( n = 15 per group) performed 80 acquisition trials of sequential timing tasks. All participants were asked to depress sequentially four keys (2, 4, 8, and 6) on the numeric pad portion of the computer keyboard with the index finger of the right hand. The author presented average feedback on timing errors based on 5-trial blocks and compared this feedback schedule with every-trial feedback. Analysis of the delaye

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Adler, Philip. "Letter To The Editor." Pediatrics 98, no. 4 (1996): 795–96. http://dx.doi.org/10.1542/peds.98.4.795b.

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In his argument supporting the Advisory Committee on Immunization Practices-recommended switch to a sequential inactivated polio vaccine/oral polio vaccine (IPV/OPV) immunization schedule (Pediatrics. 1996;98:116-117), Dr Samuel Katz fails to address the enormity of the threat that an untested immunization practice poses to an unprepared public. Dr Katz theorizes that the proposed sequential schedule may reduce the six to eight cases of vaccine-associated paralytic polio that occur each year. Yet no solid proof exists to support this claim.

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Garuti, G., M. Colonnelli, A. Soliani, C. Lubrano, and M. Soligo. "Estro-progestin and progestogen intake: What’s the impact on hysteroscopic imaging?" Facts, Views and Vision in ObGyn 15, no. 1 (2023): 61–67. http://dx.doi.org/10.52054/fvvo.15.1.056.

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Background: In current literature there is no report aimed to evaluate the effects of exogenous steroids on hysteroscopic imaging. Objectives: To evaluate the hysteroscopic features of endometrium in women undergoing female hormones administration. Material and Methods: We reviewed video-records of hysteroscopies carried-out in women taking estro-progestins (EP), progestogen (P) and Hormonal Replacement Therapy (HRT). All women underwent biopsies resulting in atrophic, functional, or dysfunctional pathological reports. Main Outcome Measures: Description of hysteroscopic pictures related to eac

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Horwitz, Steven M., Julie M. Vose, Ranjana Advani, et al. "A Phase 1/2A Open-Label Study of Pralatrexate and Gemcitabine in Patients with Relapsed or Refractory Lymphoproliferative Malignancies." Blood 112, no. 11 (2008): 1570. http://dx.doi.org/10.1182/blood.v112.11.1570.1570.

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Abstract Background: Pralatrexate (PDX) is a novel targeted antifolate that is designed to accumulate preferentially in cancer cells. Pralatrexate has demonstrated activity in the treatment of non-Hodgkin’s lymphoma (NHL). Single-agent gemcitabine (Gem) has demonstrated promising activity in relapsed Hodgkin’s lymphoma, T-cell lymphoma, and select sub-types of B-cell NHL. Based on pre-clinical data demonstrating a schedule dependent synergy for this combination (pralatrexate + Gem) (Clin Cancer Res2006; 12(3):924–932), a Phase 1/2a, non-randomized, open-label, multi-center trial was designed t

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Skene, Debra J., Elena Skornyakov, Namrata R. Chowdhury, et al. "Separation of circadian- and behavior-driven metabolite rhythms in humans provides a window on peripheral oscillators and metabolism." Proceedings of the National Academy of Sciences 115, no. 30 (2018): 7825–30. http://dx.doi.org/10.1073/pnas.1801183115.

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Misalignment between internal circadian rhythmicity and externally imposed behavioral schedules, such as occurs in shift workers, has been implicated in elevated risk of metabolic disorders. To determine underlying mechanisms, it is essential to assess whether and how peripheral clocks are disturbed during shift work and to what extent this is linked to the central suprachiasmatic nuclei (SCN) pacemaker and/or misaligned behavioral time cues. Investigating rhythms in circulating metabolites as biomarkers of peripheral clock disturbances may offer new insights. We evaluated the impact of misali

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Danilov, V. I. "Stable systems of schedule contracts." Journal of the New Economic Association 51, no. 3 (2021): 12–29. http://dx.doi.org/10.31737/2221-2264-2021-51-3-1.

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The paper studies the systems of paired contracts between agents of two complementary groups (workers and firms, students and universities, depositors and banks). Multiple contracts are allowed, as well as flexible contracts when the contract is concluded with some intensity. Agent preferences are described using choice functions. It is shown that if these choice functions satisfy the condition that we call conservativeness, then there are so-called stable systems of contracts, when it is unprofitable for any pair of counterparties to change the concluded contracts. The existence of a stable s

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Kolasa, Maureen S., Shalini N. Desai, Kristine M. Bisgard, Karen Dibling, and D. Rebecca Prevots. "Impact of the sequential poliovirus immunization schedule: a demonstration project." American Journal of Preventive Medicine 18, no. 2 (2000): 140–45. http://dx.doi.org/10.1016/s0749-3797(99)00132-4.

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Melman, Shoshana T., Elizabeth S. Ehrlich, Darren Klugman, and Ran D. Anbar. "Compliance with Initiation of a Sequential Schedule for Polio Immunization." Clinical Pediatrics 39, no. 1 (2000): 51–53. http://dx.doi.org/10.1177/000992280003900108.

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Cassinello, J., J. V. Álvarez, M. J. García-López, et al. "Capecitabine plus oxaliplatin (XELOX) followed by capecitabine plus irinotecan (XELIRI) in a sequential schedule in first-line metastatic colorectal cancer (MCRC): a phase II multicenter study." Journal of Clinical Oncology 24, no. 18_suppl (2006): 13516. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.13516.

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13516 Background: In phase II trials, XELOX and XELIRI were highly active and well tolerated in first-line MCRC. The aim of this study is to explore the efficacy and safety of XELOX followed by XELIRI as first-line treatment in MCRC. Specifically, we wanted to evaluate the impact of sequential scheduling on the dose-limiting neurotoxicity associated with oxaliplatin accumulation. Methods: Eligible patients (pts) had histologically or cytologically confirmed MCRC, ECOG PS ≤ 2 and adequate bone marrow, renal and hepatic function. Prior chemotherapy for MCRC was not allowed. Pts received 4 cycles

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Hatton, Matthew Q. F., Claire Anne Lawless, Corinne Faivre-Finn, et al. "Accelerated, Dose escalated, Sequential Chemoradiotherapy in Non-small-cell lung cancer (ADSCaN): a protocol for a randomised phase II study." BMJ Open 9, no. 1 (2019): e019903. http://dx.doi.org/10.1136/bmjopen-2017-019903.

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IntroductionLung cancer is the most common cause of cancer mortality in the UK, and non-small-cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancers. Most patients present with inoperable disease; therefore, radiotherapy plays a major role in treatment. However, the majority of patients are not suitable for the gold standard treatment (concurrent chemoradiotherapy) due to performance status and comorbidities. Novel strategies integrating radiotherapy advances and radiobiological knowledge need to be evaluated in patients treated with sequential chemoradiotherapy. Four sepa

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Hazini, Kamran, Reza Dehghan, and Janaka Ruwanpura. "A heuristic method to determine optimum degree of activity accelerating and overlapping in schedule compression." Canadian Journal of Civil Engineering 40, no. 4 (2013): 382–91. http://dx.doi.org/10.1139/cjce-2012-0380.

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Schedule compression is an attempt to reduce project durations for early delivery, or to catch up on occurred delays. This is usually performed using “crashing”, “overlapping” and “substitution” of activities. “Crashing” is shortening task duration by adding more resource hours. “Substitution” is changing the method or tool by which the activity is performed. “Overlapping” is performing sequential activities in parallel. Few studies can be found in the literature that compare costs and benefits of each technique and recommend the optimum combination of these techniques in project schedules. In

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Zhu, Bo, Xiang Ling Cao, Yu Wang, and Qiang Gao. "Constraint Programming Method for Crew Schedule Recovery." Applied Mechanics and Materials 496-500 (January 2014): 1788–91. http://dx.doi.org/10.4028/www.scientific.net/amm.496-500.1788.

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Unexpected disruptions such as aircraft failure and airport closure often make the original flight schedule cannot operate regularly and destroy the crew duties. This paper proposed a constraint programming model to solve the crew recovery problem. The total recovery cost was taken as the objective function, temporal-spacial requirements, deadheading and time legalities were considered as constraints. An algorithm based on sequential, least slack and greedy thoughts was designed to search the solution space. Finally, an example was test to indicated feasibility of the proposed model and algori

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Krasteva, Silvana, and Huseyin Yildirim. "Strategic Ignorance in Sequential Procurement." American Economic Journal: Microeconomics 11, no. 2 (2019): 131–72. http://dx.doi.org/10.1257/mic.20170076.

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Should a buyer approach sellers of complementary goods informed or uninformed of her private valuations, and if informed, in which sequence? In this paper, we show that an informed buyer would start with the high-value seller to minimize future holdup. Informed (or careful) sequencing may, however, hurt the buyer as sellers “read” into it. The buyer may, therefore, commit to ignorance, perhaps, by overloading herself with unrelated tasks, delegating the sequencing decision, or letting sellers self-schedule. Absent such commitment, we show that ignorance is not time-consistent for the buyer, bu

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Ariessanti, Hani Dewi, Dwi Sloria Suharti, and Ary Budi Warsito. "OPTIMASI PENJADWALAN PERKULIAHAN MENGGUNAKAN METODEAUTO GENERATE TIMETABLE DENGAN ARRAY." CCIT Journal 11, no. 2 (2018): 257–66. http://dx.doi.org/10.33050/ccit.v11i2.593.

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Scheduling is one of the many problems that has been done in research for many years. Problems preparing the schedule in college are about college scheduling. The timing process should be done for each semester, which is a tiring and time-consuming task. The overall allocation of events in timeslots and spaces is done by the course scheduling process by considering the list of hard constraints and soft constraints, so there is no conflict created in allocating the schedule. Therefore, it is necessary to create a lecture scheduling application that is able to facilitate and overcome the problem

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Grabitz, Hans-Joachim, and Marianne Hammerl. "Transfer effects as a function of sequential and quantitative schedule constraints." Integrative Physiological and Behavioral Science 28, no. 2 (1993): 182–85. http://dx.doi.org/10.1007/bf02691225.

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Heinemann, V., E. Estey, M. J. Keating, and W. Plunkett. "Patient-specific dose rate for continuous infusion high-dose cytarabine in relapsed acute myelogenous leukemia." Journal of Clinical Oncology 7, no. 5 (1989): 622–28. http://dx.doi.org/10.1200/jco.1989.7.5.622.

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We hypothesized that the steady-state concentration of intracellular cytarabine 5'-triphosphate (ara-CTPss) in leukemia cells is proportional to the dose rate of cytarabine (ara-C) during continuous infusion. To evaluate this possibility, patients with acute myelogenous leukemia in relapse were treated with two sequential schedules of serially increasing ara-C dose rates over a total of 36 hours. Schedule I consisted of serial infusions of 250, 500, and 750 mg/m2 each over 12 hours. Subsequently, patients entered on schedule II received 500, 1,000, and 1,500 mg/m2 serially, each over 12 hours.

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Stathis, A., S. Hotte, H. Hirte, et al. "Phase I study of intravenous decitabine in combination with oral vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas (NHL)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 3528. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.3528.

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3528 Background: Decitabine (D), a hypomethylating agent, and vorinostat (V), a histone deacetylase inhibitor, belong to two different classes of drugs with an epigenetic effect. The ideal dose scheduling of these drugs remains controversial. This phase I study aims to determine the recommended phase II dose (RPTD) of the combination, their toxicity profile, pharmacokinetic (PK) interaction and preliminary clinical activity. Methods: Patients (pts) with advanced solid tumors or relapsed/refractory NHL are eligible. Two different schedules of D and V are being evaluated: sequential administrati

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Syaputra, Muhammad Adie, and Cacah Firmansyah. "APLIKASI SMS GATEWAY SEBAGAI REMINDER JADWAL SIDANG DALAM PERKARA PERDATA (Study Kasus : Pengadilan Negeri Metro Kelas IB)." SIMADA (Jurnal Sistem Informasi dan Manajemen Basis Data) 2, no. 1 (2019): 50–63. http://dx.doi.org/10.30873/simada.v2i1.1421.

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At this time the process of calling the party related to the trial process in the Metro District Court was still carried out by calling on the Jurusita with a relatively long period of time from the stipulated trial schedule. SMS gateway is an application for utilizing SMS facilities, SMS gateway is a gateway that connects computers and clients via SMS. From the problems faced, the SMS gateway technology is applied in the trial schedule reminder system using the GAMMU application and PHP programming, so that the trial schedule information can be sent by the administrator via scheduled SMS (Sho

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LIN, DAMING, MING J. ZUO, and RICHARD C. M. YAM. "GENERAL SEQUENTIAL IMPERFECT PREVENTIVE MAINTENANCE MODELS." International Journal of Reliability, Quality and Safety Engineering 07, no. 03 (2000): 253–66. http://dx.doi.org/10.1142/s0218539300000213.

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This paper presents new sequential imperfect preventive maintenance (PM) models incorporating adjustment/improvement factors in hazard rate and effective age. The models are hybrid in the sense that they are combinations of the age reduction PM model and the hazard rate adjustment PM model. It is assumed that PM is imperfect: It not only reduces the effective age but also changes the hazard rate, while the hazard rate increases with the number of PMs. PM is performed in a sequence of intervals. The objective is to determine the optimal PM schedule to minimize the mean cost rate. Numerical exam

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Yee, Karen W. L., Mark D. Minden, Joseph Brandwein, et al. "A Phase I Trial of Two Sequence-Specific Schedules of Decitabine and Vorinostat in Patients with Acute Myeloid Leukemia (AML)." Blood 110, no. 11 (2007): 908. http://dx.doi.org/10.1182/blood.v110.11.908.908.

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Abstract Background: Epigenetic silencing of genes has been documented in AML. This phase I trial evaluates the safety, tolerability, and maximum tolerated dose (MTD) of two schedules of administration of the hypomethylating agent decitabine in combination with the pan-selective histone deacetylase inhibitor vorinostat. Methods: Patients receive escalating doses of oral vorinostat administered either sequentially [100 mg bid (n=4), 200 mg bid (n=4), or 200 mg tid (n=8) Days 6–21] or concurrently [100 mg (n=3) or 200 mg (n=6) bid Days 1–21 or 200 mg tid (n=2) Days 1–14] with decitabine (20 mg/m

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Safrin, Ali, and M. Iqbal. "Perancangan Sistem Informasi Pelabuhan Labuhan Haji Berbasis Website." Journal Digital Technology Trend 1, no. 2 (2022): 72–91. http://dx.doi.org/10.56347/jdtt.v1i2.65.

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Keeping up with technological developments applied to transportation facilities, it is very rare to find sea transportation facilities that can be accessed on a web-based basis, both from departure schedules, information and for booking tickets with one company. This research attempts to design an Android-based mobile application that can solve the problem of ticket ordering and ship departure schedules at the Sinabang Haj port crossing. This application will take advantage of the fast access that the web has that is used to order boat tickets, find out the departure schedules of various ships

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Wahyudi, Danu, and Sumarno Sumarno. "Web-Based Badminton Court Rental Information System." JICTE (Journal of Information and Computer Technology Education) 8, no. 1 (2024): 24–30. https://doi.org/10.21070/jicte.v8i1.1657.

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Badminton is a popular sport that is loved by many people in various circles of society. The Graha Sentosa meeting and sports hall is one of the many businesses that provides badminton court rentals. However, booking bookings and rental schedules still use conventional methods. This makes the manager work less effectively in recording and as a customer it is also difficult for him to see the available field schedule. The aim of creating this web-based information system is to make it easier for managers to record orders and assist customers in ordering and viewing field schedules. The research

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Chen, Yin, Xinjun Mao, Shuo Yang, and Qiuzhen Wang. "Cost-efficient inter-robot delivery for resource-constrained and interdependent multi-robot schedules." International Journal of Advanced Robotic Systems 16, no. 1 (2019): 172988141982804. http://dx.doi.org/10.1177/1729881419828049.

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A multi-robot system in resource-constrained environments needs to obtain resources for task execution. Typically, resources can be fetched from fixed stations, which, however, can be costly and even impossible when fixed stations are unavailable, depleted or distant from task execution locations. We present a method that allows robots to acquire urgently required resources from those robots with superfluous residual resources, by conducting rendezvouses with these robots. We consider a scenario where tasks are organised into a schedule on each robot for sequential execution, with cross-schedu

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Kelly, W. K., H. I. Scher, M. Mazumdar, et al. "Suramin and hydrocortisone: determining drug efficacy in androgen-independent prostate cancer." Journal of Clinical Oncology 13, no. 9 (1995): 2214–22. http://dx.doi.org/10.1200/jco.1995.13.9.2214.

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PURPOSE The combination of suramin and hydrocortisone has shown clinical benefit in patients with androgen-independent prostate cancer. Widespread use was limited by the complex dose schedules and the need for pharmacologic monitoring. This study reports three sequential pharmacokinetically derived treatment regimens that simplified the administration of suramin and hydrocortisone with reduced toxicity. PATIENTS AND METHODS Three cohorts of patients with advanced prostate cancer that progressed despite castrate levels of testosterone received oral hydrocortisone plus suramin administered in th

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Udikeri, Sarvadaman, L. Hanumantharaya, Jayalaxmi Narayan Hegde, D. Lakshmana, and Sadashiv Nadukeri. "Management of Fruit and Shoot Borer, Leucinodes orbonalis (Guenee) in Brinjal through Sequential Application of Selected Insecticides and Biorationals." International Journal of Environment and Climate Change 14, no. 1 (2024): 704–11. http://dx.doi.org/10.9734/ijecc/2024/v14i13885.

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Leucinodes orbonalis Guenee (Lepidoptera: Crambidae), commonly known as brinjal shoot and fruit borer is a dreaded pest in India. The bio efficacy of insecticides and biorationals has been test verified in managing fruit and shoot borer through logical sequential schedules. The results of the present field experiment conducted during Summer 2023 in Agricultural and Horticultural research Station (AHRS), Bavikere revealed the most effective insecticidal schedule among the tested sequences. The sequence containing Chlorantraniliprole 18.5 SC @ 0.3 ml/L - Spinosad 45 SC @ 0.4 ml/L - Lufenuron 5 E

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Ochs, J., J. Rodman, M. Abromowitch, et al. "A phase II study of combined methotrexate and teniposide infusions prior to reinduction therapy in relapsed childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study." Journal of Clinical Oncology 9, no. 1 (1991): 139–44. http://dx.doi.org/10.1200/jco.1991.9.1.139.

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Teniposide (VM-26) can increase intracellular methotrexate (MTX) and its polyglutamate derivatives in vitro and thus has the potential to improve the therapeutic index of regimens containing MTX. In this phase II study, children and adolescents with acute lymphoblastic leukemia (ALL) in first or second marrow relapse were randomly assigned to receive either simultaneous (n = 11) or sequential (n = 12) continuous infusions of MTX and VM-26 prior to reinduction. Infusions of VM-26 were begun 12 hours after completion of MTX infusion in the sequential group. Dosages were individually adjusted to

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Cha, Jae-Ryong, and Jae-Hyun Kim. "A Distributed Sequential Link Schedule Combined with Routing in Wireless Mesh Networks." ETRI Journal 34, no. 3 (2012): 462–65. http://dx.doi.org/10.4218/etrij.12.0211.0402.

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Korotkova, Yulia L., and Yury A. Mesentsev. "A risk-based approach to solving the problem of airline schedule operational management." Analysis and data processing systems, no. 4 (December 27, 2021): 19–36. http://dx.doi.org/10.17212/2782-2001-2021-4-19-36.

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The paper discusses the problem of optimal regulation of aircraft assignments for airline flights. Due to the fact that the activities of the airline are subject to changes caused by both external and internal environment, the planned schedule needs continuous management and control. In the event when the actual flight schedule deviates from the planned one, it is necessary to promptly make a decision on adjusting (restoring) the schedule and reassigning aircraft. Operational schedule management involves making adjustments to the current schedule from a depth of several hours to several days.

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Moharana, U. C., S. P. Sarmah, and Pradeep Kumar Rathore. "Application of data mining for spare parts information in maintenance schedule: a case study." Journal of Manufacturing Technology Management 30, no. 7 (2019): 1055–72. http://dx.doi.org/10.1108/jmtm-09-2018-0303.

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Purpose The purpose of this paper is to suggest a framework for extracting the sequential patterns of maintenance activities and related spare parts information from historical records of maintenance data with pre-defined support or threshold values. Design/methodology/approach A data mining approach has been adopted for predicting the maintenance activity along with spare parts. It starts with a collection of spare parts and maintenance data, and then the development of sequential patterns followed by formation of frequent spare part groups, and finally, integration of sequential maintenance

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Zavrski, Ivana, Martin Kaiser, Marleen Rosche, et al. "Bortezomib (PS-341) Sensitizes Multiple Myeloma Cell Lines to Etoposide-Induced Apoptosis." Blood 106, no. 11 (2005): 5166. http://dx.doi.org/10.1182/blood.v106.11.5166.5166.

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Abstract Proteasome inhibitor bortezomib interacts with the regulation of protein turnover in eukaryotic cells. The results of proteasomal inhibition consist in cell cycle arrest and induction of apoptosis. Etoposid targets topoisomerase IIα and is included in several protocols for myeloma treatment. In this study, we examined the effects of simultaneous and sequential treatments of bortezomib and the topoisomerase IIα inhibitor etoposide in multiple myeloma cell lines, particularly in terms of potential synergistic effects between both drugs. Using the MTT assay, cytotoxicity levels for dosag

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Al-Harthy, M. H., A. K. Khurana, S. Begg, and R. B. Bratvold. "SEQUENTIAL AND SYSTEMS APPROACHES FOR EVALUATING INVESTMENT DECISIONS—INFLUENCE OF FUNCTIONAL DEPENDENCIES AND INTERACTIONS." APPEA Journal 46, no. 1 (2006): 511. http://dx.doi.org/10.1071/aj05031.

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Development decision-making practices in the oil and gas industry focus on detailed modelling of every decision parameter—such as reserves, production schedule, facilities design, costs and prices—individually, without due attention to the dependencies and interactions between these parameters. Dependencies and interactions are captured in modelling of uncertainties in some parts of the system (such as reserves and production schedules) but not in others.Modelling uncertainty without modelling dependencies fails to benefit from investing in the values of flexibility and information. Modelling

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Cheng, Min-Yuan, Quoc-Tuan Vu, and Frederik Elly Gosal. "Hybrid deep learning model for accurate cost and schedule estimation in construction projects using sequential and non-sequential data." Automation in Construction 170 (February 2025): 105904. https://doi.org/10.1016/j.autcon.2024.105904.

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Yu, Catherine, Alaina Kessler, Theresa Shao, Sarah Cate, Paula Klein, and Manjeet Chadha. "Abstract PO5-03-09: Concurrent versus sequential use of adjuvant capecitabine and radiation in patients with triple-negative breast cancer with residual disease: A retrospective review." Cancer Research 84, no. 9_Supplement (2024): PO5–03–09—PO5–03–09. http://dx.doi.org/10.1158/1538-7445.sabcs23-po5-03-09.

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Abstract Background: The CREATE-X trial demonstrated benefit of adjuvant capecitabine for patients with triple-negative breast cancer (TNBC) with residual disease after neoadjuvant chemotherapy and surgery. In clinical practice however, physician discretion determines the sequence of capecitabine relative to radiation therapy (RT), as well as the treatment dose. Therefore, our study aimed to assess the treatment patterns and tolerance of capecitabine and RT in patients with residual TNBC at our institution after publication of the CREATE-X study. Methods: This was a retrospective IRB-approved

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Ben-Shatach, Zohar, Tomer Ziv-Baran, Ella Fudim, et al. "Delaying an infliximab infusion by more than 3 days is associated with a significant reduction in trough levels but not with clinical worsening." Therapeutic Advances in Gastroenterology 15 (January 2022): 175628482210833. http://dx.doi.org/10.1177/17562848221083395.

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Background: Higher infliximab trough levels (TLs) correlate with better clinical, inflammatory, and endoscopic outcomes among inflammatory bowel disease (IBD) patients. Although standard scheduled infliximab therapy regimen consists of infusions at pre-defined time-points (weeks 0, 2, 6, and every 8 weeks), short-period deviations from therapeutic schedule are common in ‘real life’, but the pharmacokinetic impact of these deviations has not been explored. In this study, we aim to determine whether short-period deviations from infusion schedule affect infliximab-TL. Methods: A retrospective ana

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Sprenger, Ralf, Dennis Häckl, Nils Kossack, Julia Schiffner-Rohe, Jessica Wohlleben, and Christof von Eiff. "Pneumococcal vaccination rates in immunocompromised patients in Germany: A retrospective cohort study to assess sequential vaccination rates and changes over time." PLOS ONE 17, no. 3 (2022): e0265433. http://dx.doi.org/10.1371/journal.pone.0265433.

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Background Pneumococcal vaccination is recommended by the German Standing Committee on Vaccination (STIKO) for infants, elderly 60+ years and patients at risk. In 2016, a sequential pneumococcal vaccination schedule (conjugate vaccine followed by polysaccharide vaccine 6–12 months later) supplemented this recommendation for immunocompromised patients ≥2 years of age. Previous research showed low pneumococcal vaccination rates (pnc-VR) in this vulnerable group. Moreover, no evidence is available on adherence to the newer sequential schedule. This study aimed to analyze the development of pnc-VR

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