Dissertations / Theses on the topic 'Series B'
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Jaunzems, Davis. "Time-series long-term forcasting for A/B tests." Thesis, KTH, Skolan för informations- och kommunikationsteknik (ICT), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-205344.
Full textThe technological development of computing devices and communication tools has allowed to store and process more information than ever before. For researchers it is a means of making more accurate scientific discoveries, for companies it is a way of better understanding their clients, products and gain an edge over the competitors. In the industry A/B testing is becoming an important and a common way of obtaining insights that help to make data-driven decisions. A/B test is a comparison of two or more versions to determine which is performing better according to predetermined measurements. In combination of data mining and statistical analysis, these tests allow to answer important questions and help to transition from the state of “we think” to “we know”. Nevertheless, running bad test cases can have negative impact on businesses and can result in bad user experience. That is why it is important to be able to forecast A/B test long-term effects from short-term data. In this report A/B tests and their forecasting is looked at using the univariate time-series analysis. However, because of the short duration and high diversity, it poses a great challenge in providing accurate long-term forecasts. This is a quantitative and empirical study that uses real-world data set from a social game development company King Digital Entertainment PLC(King.com). First through series of steps the data are analysed and pre-processed. Time-series forecasting has been around for generations. That is why an analysis and accuracy comparison of existing forecasting models, like, mean forecast, ARIMA and Artificial Neural Networks, is carried out. The results on real data set show similar results that other researchers have found for long-term forecasts with short-term data. To improve the forecasting accuracy a time-series clustering method is proposed. The method utilizes similarity between time-series through Dynamic Time Warping, and trains separate cluster forecasting models. The clusters are chosen with high accuracy using Random Forest classifier, and certainty about time-series long-term range is obtained by using historical tests and a Markov Chain. The proposed method shows superior results against existing models, and can be used to obtain long-term forecasts for A/B tests.
Nefdt, Ryan. "The metaphysics of time investigations in tense-logic and a B-series semantics." Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/3669.
Full textThe view that time flows from the future to the present and then recedes into the past is both natural and deeply problematic. So called 'A-theories' about time claim that this is the fundamental nature of temporality. This is not the view which will be defended in this paper. Rather I shall argue for what is known as a 'B-theory' analysis of time and language, one in which the relations of 'earlier than' and 'later than' are necessary and sufficient for any analysis of time. The structure of this paper is tripartite. The first part will address the philosophical and metaphysical tenets of both the A and B-theories of time. In this section, McTaggart's 1908 argument for the unreality of time will be presented along with some objections to it. I will show that some seemingly convincing arguments against 'McTaggart's paradox' are unsuccessful and his paradox does indeed call the A-series into question. This section will lay the groundwork for further discussions relating to other disciplines which are concerned with this debate by describing the issues and points of tension.
Silver-Warner, Stephen John. "Associative memory neural networks : an investigation with application to chaotic time series prediction." Thesis, Brunel University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362486.
Full textArnold, Douglas E. II. "Comparison of Achievement in 7A/B Block Scheduled Schools and 7-Period Traditional Scheduled Schools in Virginia." Diss., Virginia Tech, 1998. http://hdl.handle.net/10919/30428.
Full textEd. D.
Shraberg, Joshua. "A Computational Study of Procyanidin Binding to Histatin 5 and Thermodynamic Properties of Hofmeister-Anion Binding to a Hydrophobic Cavitand." ScholarWorks@UNO, 2014. http://scholarworks.uno.edu/td/1944.
Full textSauzeau, Julie. "Variété centrale hautement oscillante et une application en écologie." Thesis, Rennes 1, 2016. http://www.theses.fr/2016REN1S018/document.
Full textWe have studied a differential system ruled by two dynamics : a center manifold dynamics and a periodic highly oscillating dynamics. We wanted to find informations about the qualitative behaviour of the system, and to approximate it. We have proved the existence of a highly oscillating asymptotic dynamics, and we have used it approximate the system. Then, we have applied this results to an ecological system of prey-predator interaction. Moreover, we have used the B-series theory to obtain formal expansions of the quantities related to the center manifold. Lastly, we have approximated the system for all time by the composition of a change of variable and of the solution of a partially decoupled differential system
Oliveira, Fernando Esteves de. "O presentismo como resposta ao paradoxo de McTaggart." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/170403.
Full textOne of the most important milestones of contemporary philosophy of time is the paper by McTaggart (1908) "The Unreality of Time", in which he argues that the existence of time is contradictory. The work in question took a few decades to have its philosophical importance duly acknowledged, mainly due to the difficulty of the second part of McTaggart’s argument, which came to be called “McTaggart’s Paradox”, since it does not show the consistency of the assumption that time is unreal, but that the idea of the existence of what is commonly understood by time is inconsistent due to a contradiction in applying the predicates of being past, present or future. There are some authors who consider the McTaggart's argument very plausible, and have developed responses to it in order to ensure the reality of time, abandoning some of the fundamental notions that are usually attributed to time. One of these responses is called presentism, and consists in the assumption that all and only what exists is present and all and only what is present exists. That response faces some difficulties, like the difficulty of the truthmakers, the makers of the truth-value of assumptions about the past and the future, since only the present exists, or the difficulty reconciling presentism and Relativity Theory. The purpose of this dissertation, then, is to examine McTaggart's Paradox, analyzing the requirements needed to interpret it in a way that is consistent. If the argument shows itself sound, the next step will be to analyze presentism as a coherent theory in order to finally verify the possibility of using presentism as a concrete alternative for interpreting reality in which time is real, solving the McTaggart’s Paradox.
Miranzi, Sybelle de Souza Castro. "Análise de tendência temporal: uma alternativa para avaliação do impacto da vacinação contra Haemophilus influenzae tipo b, no Brasil." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/22/22133/tde-18122007-153143/.
Full textMeningitis is an important disease within the national health system, due to its epidemiological characteristics and socioeconomic impact. The Haemophilus influenzae (HIB) type B causes respiratory infections as well as invasive diseases such as meningitis, pneumonias, epiglottitis, sinusitis, bacteremias, otitis and arthritis. Among these diseases, the meningitis has been the most studied due to its high morbi-mortality rate and also because requires compulsory notification. The purpose of this study was to evaluate the trend, considering the history series, regarding morbi-mortality and case fatality rates of meningitis caused by Hib in Brazil, as an alternative for the evaluation of the impact of a specific vaccination. This research was an ecologic observation from 1983 to 2002. The author calculated the incidence, mortality and case fatality rates of Hib meningitis, based on data from the National Health Department and the Geography and Statistics Brazilian Foundation Institute. In order to analyze these indicators\' trends, authors estimated prediction lines, with confidence intervals of 95%. The softwares used to manage and analyze data were: Excel, Epiinfo and Stata. In Brazil, from 1983 to 2002, 23.921 cases of Hib meningitis were notified. Among them, 10.524 (43.99%) in babies with less than one year and 9.269 (38.75%) in children with age varying from 1 to 4 years. The higher magnitude of incidence, mortality and case fatality rates were observed in the ages less than 1 year and varying from 1 to 4 years. Since 1988, the author observed an increment in the magnitude of the incidence and mortality rates. The North and Northeast regions presented a lower magnitude for these indicators, while for case fatality, the Northeast region presented indicators of higher magnitude in babies with age less than 1 year old. In general, although the case fatality rates presented a decreasing pattern since the beginning of the series, its magnitude was high until 2001. The impact of vaccination on case fatality rates was perceived only after 2002, suggesting that it can take three years, in average, to have some effect on the Hib meningitis prognosis. With exception to the Northeast region, the trends regarding the incidence and mortality in Brazil were similar, in the pre-vaccination period (increase), detecting a decrease after the introduction of vaccination in the routine of the do Programa Nacional de Imunização. In Brazil and in the North, Northeast, South and Southeast (age less than one year) regions, the case fatality trend was of decline during all series. In the Centerwest and Southwest regions, the impact of the vaccination introduction on the incidence and mortality rates was precocious (1999-2000), if compared to the other regions studied and maybe due to the fact that in these regions the vaccination achieved a greater amount of the population. The impact of vaccination was clearer on the incidence and mortality than on the case fatality rates. Results revealed a positive impact of the vaccination strategies against Hib in Brazil and in macro regions, including the age ranges that were not vaccinated. The author recommends the continuous monitoring of these diseases, through epidemiological surveillance actions and the improvement of the Health Information System.
Losey, Arthur Bill. "STRUCTURAL VARIATION IN THE PHOSPHATE OLIVINE LITHIOPHILITE-TRIPHYLITE SERIES AND CHARACTERIZATION OF LIGHT ELEMENT (Li, Be, AND B) MINERAL STANDARDS." Miami University / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=miami1015014954.
Full textFulat, Alper Ihsan. "Investigating Time Series Shoreline Changes By Integration Of Remote Sensing And Geographical Information Systems." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12606912/index.pdf.
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k Menderes Delta, by geographical information systems for the last fifty-year period, in order to approximate future shoreline position of Bü
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k Menderes Delta shoreline, and to evaluate appropriate models while predicting the future shoreline position. To achieve the purpose of the study time series shoreline position data is extracted from three sets of topographic maps belonging to 1954-1957, 1977-1978 and 1993 aerial photographs and two sets of high resolution satellite imageries (January 2002 Ikonos, August 2004 QuickBird). Then Coastal script of TNTMips, which uses some statistical shoreline analyses methods, that are End Point Rate (EPR), Average of Rates (AOR), Linear Regression (LR) and Jackknifing (JK) is edited so that it can locate the future shoreline positions on the map. Suitable baselines are created and appropriate transect intervals are decided to analyze the shoreline. Finally, some additional analyses that are Backward Analysis and Oscillation Analysis are done to obtain most suitable future shoreline position with rate-of-changes. The results showed that, shorelines having different geomorphologic characteristics needed to be analyzed separately and the linear methods to model the future shoreline position differ from one geomorphologic region to another.
Mineo, Eduardo Phillipe. "DCOBS: forecasting the term structure of interest rates with dynamic constrained smoothing B-Splines." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/45/45132/tde-16012018-111318/.
Full textO framework Nelson-Siegel publicado por Diebold e Li uma década atrás criou um importante benchmark e originou diversos trabalhos na literatura de previsão de estrutura a termo de taxas de juros. Por exemplo, o framework Nelson-Siegel Livre de Arbitragem melhorou a performance preditiva impondo condições de não-arbitragem ao framework Nelson-Siegel. No entanto, estes frameworks foram construídos em cima do modelo de curvas paramétricas. Em casos mais sensíveis de formas de curvas, este modelo tem um desempenho muito ruim, afetando o resultado da previsão. Nós propomos o DCOBS com restrições de não-arbitragem para prever a estrutura a termo. Ele é construído em cima do modelo de curva não-paramétrico com B-Splines restritas e suavizadas. Este modelo demonstrou ser uma solução ótima entre integridade financeira e respeito às formas de curvas de juros. Embora este modelo de curva possa resultar em curvas forwards mais voláteis que os modelos paramétricos, ele é ainda mais acurado que aqueles do framework Nelson-Siegel. Um software foi desenvolvido com uma implementação completa das técnicas de ajustes de curvas de juros discutidas nesta dissertação. DCOBS foi avaliado utilizando dez anos de dados de títulos públicos do governo brasileiro e demonstrou boa consistência com os fatos estilizados das curvas de juros. Os resultados do DCOBS são promissores, especialmente na previsão de curto prazo, e demonstrou maior estabilidade e menor erro quadrático médio que o modelo Nelson-Siegel Livre de Arbitragem.
Fernandes, Marlene Neves. "Saberes em foco: diálogos de M. B. Lourenço Filho na série de leitura graduada Pedrinho (1953 1970)." Universidade do Estado de Santa Catarina, 2011. http://tede.udesc.br/handle/handle/1064.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
In this master's degree dissertation, are presented the results of the research held on the reading textbooks written and produced between 1953 to 1957 by Teacher Manoel Bergström Lourenço Filho (1897- 1970), aimed at students of primary public schools of the country. Known as the Pedrinho Graduate Reading Series, consisted of four literature books and a reading primer, namely: Pedrinho (1953), Pedrinho e seus amigos (1954), Aventuras de Pedrinho (1955), Leituras de Pedrinho e Maria Clara (1956), and the primer, Upa, cavalinho! (1957) All published by Companhia Editora Melhoramentos, (SP). For the elaboration of the Series (Lourenço Filho), beyond the texts of his authorship, selected excerpts were taken from work already published by other authors, all of whom appeared throughout the four books of literature in the form of lessons. These textbooks were produced with the intention to stimulate the desire to read with comprehension in a productive form, and the second specifies the actual author on the presentation of the first volume of The first grade to watch the problems of human relations at home, at school, and in the social life (LOURENÇO FILHO, 1961). Approached based upon the assumptions of the Educational History in interface with the books history and the literature, is centered in researched bibliography and documentary. The objective of the present job consists of elaborating in a mapping of the authors chosen by Lourenço Filho to compose the scope of Series. From this survey, only a few authors were highlighted, due to those who contributed more in terms of quantity of lessons published, and identified himself to learn more focus placed on those same lessons. This analyses created possibilities to conclude what, in the historic moment in which what was published and utilized, as selected lectures continued knowing who composed the Primary Education pertaining to various disciplines; however, it was found that Lourenço Filho, whom chose authors to write the Series, emphasized texts that privileged knowledge especially dedicated to the teaching of History and Geography in Brazil as disciplines formed the Brazilian nationality
Nesta dissertação de mestrado, são apresentados os resultados de pesquisa realizada nos manuais escolares de leitura escritos e produzidos entre 1953 e 1957 pelo prof. Manoel Bergström Lourenço Filho (1897 1970), voltados a alunos de escolas primárias públicas do País. Conhecida como Série de Leitura Graduada Pedrinho, era composta por quatro livros de leitura e uma cartilha, a saber: Pedrinho (1953), Pedrinho e seus amigos (1954), Aventuras de Pedrinho (1955), Leituras de Pedrinho e Maria Clara (1956), e a cartilha Upa, cavalinho! (1957), todos publicados pela Companhia Editora Melhoramentos (SP). Para a elaboração da Série, Lourenço Filho, além de textos de sua autoria, selecionou variados trechos de obras já publicados por outros autores e autoras que figuram ao longo dos quatro livros de leitura em forma de lições. Esses manuais escolares foram produzidos com a pretensão de estimular a vontade de ler com compreensão, de forma produtiva, bem como, segundo explicita o próprio autor na apresentação do primeiro volume, ser a primeira série a cuidar dos problemas das relações humanas no lar, na escola e na vida social (LOURENÇO FILHO, 1961). Mediante abordagem baseada nos pressupostos da História da Educação em interface com a História do Livro e da Leitura e centrado em pesquisa bibliográfica e documental, o objetivo do presente trabalho consiste em elaborar um mapeamento dos autores e autoras escolhidos por Lourenço Filho para compor o escopo da Série. A partir desse mapeamento, destaca-se os que mais contribuíram em termos de quantidade de lições publicadas, bem como identificou-se os saberes mais colocados em foco nessas mesmas lições. Esta análise criou possibilidades para concluir que, no momento histórico em que foi publicada e utilizada, as lições selecionadas continham saberes que compunham o Ensino Primário concernentes a diversas disciplinas; entretanto, verificou-se que Lourenço Filho, ao escolher autores para compor a Série, enfatizou textos que privilegiavam especialmente saberes dedicados ao ensino da História e da Geografia brasileiras identificadas como disciplinas formadoras da nacionalidade
Tang, Lin. "Efficient Inference for Periodic Autoregressive Coefficients with Polynomial Spline Smoothing Approach." University of Toledo / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1449770216.
Full textRocchi, Clizia. "Proposta di sottotitolaggio della serie tv spagnola B&b de boca en boca." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8187/.
Full textRiemer, Nathanael. "Yoav Elstein/Avidov Lipsker/Rella Kushelevsky (Hg.): Enziklopediya shel Enziklopediya shel ha-Sippur ha-yehudi : Sippur okev Sippur ; Kerah B. [Encyclopedia of the Jewish Story : Sippur okev Sippur, Vol. 2. Thema ; A Series of Thematological Studies in the Literature of the Jewish People] / [rezensiert von] Nathanael Riemer." Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5335/.
Full textMillspaugh, Gary F. "Use of the Stewart B. McKinney Homeless Assistance Act by two small cities." Instructions for remote access. Click here to access this electronic resource. Access available to Kutztown University faculty, staff, and students only, 1991. http://www.kutztown.edu/library/services/remote_access.asp.
Full textDartiguelongue, Caroline. "Contribution a la synthese de derives 2-hydroxyethylamine en serie cylopenta(b) cyclohexa(b) furaniques a proprietes antivirales et cytotoxiques potentielles." Angers, 1997. http://www.theses.fr/1997ANGE0502.
Full textMondschein, Lauri A. "The development of an interactive computer program to be used as a teaching aid in a college course covering A/B roll editing." Instructions for remote access. Click here to access this electronic resource. Access available to Kutztown University faculty, staff, and students only, 2002. http://www.kutztown.edu/library/services/remote_access.asp.
Full textSource: Masters Abstracts International, Volume: 45-06, page: 2808. Typescript. Abstract precedes thesis as 2 preliminary leaves. Includes bibliographical references (leaves 45-47).
MONNOT, JACQUARD BENEDICTE. "Traitement de l'hepatite chronique post-virale b par l'association vidarabine monophosphate - interferon alpha recombinant : resultats preliminaires obtenus dans une serie de 13 patients." Besançon, 1994. http://www.theses.fr/1994BESA3027.
Full textMADADI, MESSAOUD NACER. "Recherche en pharmacochimie heterocyclique antiparasitaire : pharmacomodulation de derives thiopheniques et reactions de transfert monoelectronique en serie imadazo (1,2-a) pyridine et en serie imadazo (2,1-b) thiazole." Aix-Marseille 2, 1991. http://www.theses.fr/1991AIX22956.
Full textLEBRETON, LUC. "Syntheses de nouvelles molecules en serie heterocyclique. Etude de leur activite inhibitrice sur les monoamines oxydases a et b." Paris 7, 1989. http://www.theses.fr/1989PA077272.
Full textBuxton, Robert S. "Musical Time and Memory: A Bergsonian Interpretation of Sergei Rachmaninoff's Prelude Op. 32 No. 10 in B Minor." Thesis, University of North Texas, 2018. https://digital.library.unt.edu/ark:/67531/metadc1248480/.
Full textRoth, Emily Renee. "An examination of major works for concert band and chamber ensembles: Down a Country Lane by Aaron Copland, Two Pieces from Lieutenant Kije by Sergei Prokofiev, and Suite in B-flat by Richard Strauss." Kansas State University, 2015. http://hdl.handle.net/2097/19089.
Full textDepartment of Music, Theatre, and Dance
Frank C. Tracz
The following report is a detailed analysis on the following three pieces: Suite in B-flat by Richard Strauss for woodwind chamber ensemble, Two Pieces from Lieutenant Kije by Sergei Prokofiev for brass and percussion ensemble, and a finally Down a Country Lane by Aaron Copland for concert band. The goal of the analysis is to provide rehearsal information for educational purposes. Aspects of the compositions studied include: background information on the composer and composition, a historical perspective, technical and stylistic considerations, and the musical elements. The researchers perspective on philosophy of music education is also stated as well as the importance of choosing quality literature for pedagogical needs and performance. The goal of this report is to aid future conductors in their performances of the literature and for that reason the seating charts for the ensembles, acoustical justifications, as well as rehearsal plans have been included.
Wittchen, Sergei [Verfasser], Ralf B. [Gutachter] Wehrspohn, Mario [Gutachter] Beiner, and Dirk [Gutachter] Enke. "Untersuchung von langfristigen Haftungs- und Wechselwirkungsmechanismen Polyurethan-basierter Beschichtungen auf thermoplastischen Substraten unter Einfluss alkoholischer und wässriger Umgebungsmedien / Sergei Wittchen ; Gutachter: Ralf B. Wehrspohn, Mario Beiner, Dirk Enke." Halle (Saale) : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2020. http://d-nb.info/122297486X/34.
Full textLiu, Louise Jiayin. "Sergei Taneyev (1856-1915): An Analysis of His Piano Concerto in E-flat Major and Its Relationship to Tchaikovskys Piano Concerto No.1." Thesis, University of North Texas, 2007. https://digital.library.unt.edu/ark:/67531/metadc3648/.
Full textCouch, Roy L. "Comparison and Contrast of Performance Practice for the Tuba in Igor Stravinsky's The Rite of Spring, Dmitri Shostakovich's Symphony No. 5 in D major, Op. 47, and Sergei Prokofiev's Symphony No. 5 in B flat major, Op. 100." Thesis, connect to online resource, 2006. http://www.unt.edu/etd/all/May2006/couch%5Froy%5Flee/index.htm.
Full textSystem requirements: Adobe Acrobat Reader. Accompanied by 4 recitals, recorded June 25, 2001, Nov. 18, 2002, Mar. 21, 2005, and Feb. 20, 2006. Includes bibliographical references (p. 44-48).
Sessions, John W. "In Vitro Molecular Modification of Human Cultured and Primary Cells Using Lance Array Nanoinjection." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/5859.
Full textRicker, William, and John Jr Kolb. "A HIGH-SPEED, RUGGEDIZED, MINIATURE INSTRUMENTATION RECORDER UTILIZING COMMERCIAL TECHNOLOGY." International Foundation for Telemetering, 1992. http://hdl.handle.net/10150/608915.
Full textDue to the vast amount of data required to be collected for design/performance analysis of operational and development systems, there has evolved a real requirement for a high-speed, large capacity, data collection/record system in a small Flight/Ruggedized package. This need is realized by several user communities and factors which include the evolution of small operational vehicles (airborne, land and UAV’s), the desire of weapons manufacturers/integrators to be independent from the vehicle during vehicle integration, and a general need for a field/airborne, reliable portable data collection system for intelligence gathering, operational performance verification and on-board data processing. In the Air Defence community, the need for a ruggedized record system was highlighted after Desert Storm, in which the operational performance of the Patriot Missile was questioned and data collection was not performed to support the performance. The Aydin Vector Division in conjunction with the prime contractor, has come up with a solution to this problem which utilizes a commercially available helical scan 8mm data storage unit. This solution provides a highly reliable record system, ruggedized for airborne and field environments and a low price in comparison with the more traditional approaches currently offered. This paper will describe the design implementation of this small ruggedized, flight worthy Data collection system deemed the ATD-800. It will also discuss the performance and limitations of implementing such a system, as well as provide several applications and solutions to different operational environments to be encountered. Additionally, the paper will conclude with several product enhancements which may benefit the flight test, operational and intelligence communities in the future.
Rajnoha, Andrej. "Polohování objektu ve 3D prostoru pomocí paralelního lanového robota." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2016. http://www.nusl.cz/ntk/nusl-240842.
Full textDomínguez, Solà David. "Mecanismes de regulació en l'activitat biològica del factor de transcripció Snail." Doctoral thesis, Universitat Pompeu Fabra, 2003. http://hdl.handle.net/10803/7065.
Full textEn els mamífers l'activitat d'Snail és modulada per dos mecanismes. (i) En el promotor humà es troben regions definides de resposta a factors repressors, predominants en les cèl·lules epitelials, i elements diferenciats de resposta a inductors de la "transició epiteli-mesènquima". (ii) L'activitat d'Snail és condicionada també per la seva localització subcel·lular, modulada per mecanismes no transcripcionals: la fosforilació d'Snail determina si és o no exclós del nucli. Al citosol no pot actuar com a repressor transcripcional però pot interaccionar amb la xarxa microtubular, que estabilitza i en condiciona el dinamisme. Això coincideix amb l'activació de la GTPasa RhoA i la reorientació dels filaments de vimentina, fets associats a l'adquisició de capacitat migratòria. L'efecte com a repressor transcripcional i la modulació del dinamisme microtubular són possiblement esdeveniments coordinats necessaris per al rol biològic d'Snail en mamífers.
Snail family of transcription factors is fundamental to the "epithelial-mesenchymal transition", morphogenic process essential to embryonic development and metastatic phenomena in tumors.
Snail's activity is modulated in two ways in mammals. (i) The human promoter harbors definite regions that respond to repressor factors, which prevail in epithelial cells; and differentiated elements that respond to known inducers of the "epithelial-mesenchymal transition". (ii) Snail's activity is also conditioned by its subcellular localization, mechanism not dependent on its transcriptional control: Snail phosphorylation determines whether Snail is excluded or not from the nucleus. When in the cytosol, Snail is unable to act as a transcriptional repressor, but however binds to the microtubular meshwork, which becomes stabilized and whose dynamism is conditioned as a result. This fact coincides with the activation of the RhoA GTPase and reorientation of vimentin filaments, both phenomena being related to the acquisition of cell motility. The transcriptional repressor and the microtubule dynamics effects are probably two coordinated events necessary to Snail's biological role in mammals.
Yu-Fang, Jhang, and 張玉芳. "The Photophysical and Photochemical Properties of 2-Styrylquinoline Derivatives:(a) 5-Member Hetero-ring series (b) 8-Hydroxyquinoline series." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/4jws85.
Full text國立嘉義大學
應用化學系研究所
96
Different 2-styrylquinoline derivatives possessing intramolecular charge transfer characters, including 5-member heterocyclic or 8-hydroxyquinoline, were synthesized to study the influence of substituent on the photophysics and photochemistry. For 5-member heterocyclic derivatives, the basicity of the quinoline ring are enhanced in excited state (pKa ⊿= 8 ~ 10). Comparing with thiophene derivatives, pyrrole ring possesses a stronger electron-donating ability. However, these molecules all practiced an excited state proton transfer (ESPT) reaction in strong hydrogen donor solvents, such as the mixed solvents (dichloromethane and trifluoroethanol). The electronic effect of the hydroxyl group depends on the substituent effect for the 8-hydroxyquinoline derivatives. When a strong electron-donating group, such as –NMe2, appeared as a donor part on the 8-hydroxyquinoline derivatives, the hydroxyl group behaves an electron-withdrawing group. However, the hydroxyl group becomes as an electron-donating group when –NMe2 was replaced by –NO2 or protonated –NMe2. The discovery of the electronic-effects inversion for the hydroxyl group on the 8-hydroxyquinoline derivatives is important in studying the mechanism of the ESPT.
Poleri, Isabel Filipa Ribeiro. "Incidence and characteristics of type B aortic dissection - a single center series." Dissertação, 2018. https://repositorio-aberto.up.pt/handle/10216/111966.
Full textPoleri, Isabel Filipa Ribeiro. "Incidence and characteristics of type B aortic dissection - a single center series." Master's thesis, 2018. https://hdl.handle.net/10216/111966.
Full textWaibel, Fabian. "Arithmetic and analytical aspects of Siegel modular forms." Doctoral thesis, 2020. http://hdl.handle.net/21.11130/00-1735-0000-0005-1496-B.
Full textHuang, Chun-Chieh, and 黃俊傑. "Assessment of Carotid Artery Distensibility Using Approximate Entropy and B-mode Ultrasound Image Series." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/10855193807750494952.
Full text國立中正大學
資訊工程研究所
102
World Health Organization showed that cardiovascular disease is the main cause of death around the world, and the number of death is increasing every year. Atherosclerosis is an important factor that causes cardiovascular disease, and more and more clinical practices uses arterial stiffness to diagnose cardiovascular disease. The carotid artery is the main channel of blood supply to the brain, and also the predilection sites of atherosclerosis. Therefore it is an important diagnostic site to prevent stroke. Carotid artery is only 1 to 2 cm below the skin surface, and the lesions on arterial wall can be assessed by ultrasound imaging plus the experience and skill of the operator. In the past the researchers only considered the instantaneous changes of lumen cross-section area and blood pressure between the systolic and diastolic period, which is fundamentally problematic and controversial because these changes are impressionable by many factors. Our objective is to develop an image processing tool that allows users to easily obtain the long term information of the arterial geometry, and quantify the temporal variation by approximate entropy in order to correlate with arterial distensibility. Our experimental results show that the extracting cross-sectional area from carotid artery image series is reliable and consistent. The imaging rates and data length must be fixed when assessing arterial distensibility by approximate entropy. The site of imaging does not change the estimation results. The estimated arterial distensibility increased after short-term exercise. Other people showed the same phenomenon by using aortic pulse wave velocity (APWV). We also found such assessment is reproducible according to our repeated experiments. In all the experiments we compared approximate entropy with the common statistical measure, variance, and found approximate entropy is a better and convincing indicator for carotid atherosclerosis.
Lin, Chien-ho, and 林建和. "Preliminary Study on the Effect of Leading Edge Protuberances on B-Series Propeller’s Performance." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/56865593884975467982.
Full text國立成功大學
系統及船舶機電工程學系碩博士班
97
The purpose of this study of propeller performance improvement at low propeller advance coefficient is to explore effect of the leading edge change that is similar to the humpback whales’ flipper Protuberances. In this paper, the experiment of B-series propeller (B4-70) with two different forms of leading edge change were carried out in a towing tank, including propeller performance experiments and visualization of propeller flow field. The results of performance experiments show that the efficiency of leading edge changes is not better at low advance coefficient (J=0~0.55), but slightly declines at high advance coefficient (J>0.55). Flow visualization results showed that the tufts behind leading-edge protuberances do not have obvious swinging, meaning that vortex and turbulence is not strong. This is different from 2-dimensional wing with protuberances. The reason is probably that most part of the propeller did not reach stall regime, such that the effect of protuberances is not obvious. The effect of swept leading edge and twisted blade needs further study.
Siao, Zonghan, and 蕭宗瀚. "Magnetic properties, phase evolution, and microstructure of Nd-Fe-Ti-Zr-B series rods and ribbons." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/04120110833758206697.
Full text國立中正大學
物理學系暨研究所
100
In order to simplify the manufacturing the processes for making isotropic magnets, we adopted the copper mould casting method to fabricate Nd-Fe-B-type alloy rods. At first, the effect of external magnetic field applied solidification on the magnetic properties of Nd9.5Febal.Ti2.5Zr0.5Cr1B14.5C0.5 rods with different cooling rate has been studied. Applying external magnetic field during solidification could refine the grain size of the rods, resulting in the improvement of magnetic properties. Nevertheless, it is found that the slower the cooling rate, the larger the effect of external field on the magnetic properties enhancement of the bulk magnets is. Second, magnetic properties, phase evolution, and microstructure of Nd9.5-1.5xFebal.Ti2.5Zr0.5B15+2x (x=0、1、2、3、4) rods and ribbons are studied. For both rods and ribbons, with increasing x, 4πM12kOe increases and iHc decreases due to the increase of the volume fraction of t-Fe3B、o-Fe3B phase and the decrease of 2:14:1 phase, while the volume fraction of t-Fe3B phase may decrease and o-Fe3B phase increase with increasing the annealing temperature. The optimal magnetic properties of Br = 6.1 kG, iHc = 11 kOe, (BH)max = 7.2 MGOe and Br = 7.2 kG, iHc = 13.4 kOe, (BH)max =10 MGOe could be obtained for Nd9.5Febal.Ti2.5Zr0.5B15 rod and ribbon, respectively. Finally, the magnetic properties and microstructure of Nd9.5Febai.Ti2.5Zr0.5B23 and Nd6.5Y3Febai.Ti2.5Zr0.5B23 alloy with various diameters (0.9 - 2.5 mm) are compared. The magnetic properties of both series alloys are decreased with the increase of diameter, but the glass forming ability is obviously enhanced by Y addition. As a result, the rod magnet with a diameter of 2.5 mm annealed at 750 ◦C could also exhibit attractive magnetic properties arisen from its finer microstructure. The Br = 5.0 kG, iHc = 10.6 kOe, and (BH)max = 4.7 MGOe were attained for Nd6.5Y3Febai.Ti2.5Zr0.5B23 rod magnet.
Papish, Volodymyr Gregory. "The Hecke C*-algebra of the ax + b group of the Laurent series over a finite field." 2005. http://hdl.handle.net/1828/688.
Full textWANG, MU-HUA, and 王睦華. "The Application of Time Series Forecasting Method and Data Mining to Lean Production-A Case Study of Sales Forecasting in B Company." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/qy66d9.
Full text國立虎尾科技大學
工業管理系工業工程與管理碩士班
107
Many small and medium enterprises started original design manufacturer and then developed their own brands in Taiwan. Faced with many challenges in the process,how to solve the waste problem in order to achieve cost reduction and profits increased is a major issue for companies.Lean production management focused on eliminating waste,reduced inventory and improved productivity.This study is based on lean production management.Through the discussion of the existing waste of case study and proposed the improvement plans.To predict the product sales by constructing a sales forecast model.Instead of maintaining resources in anticipation of what might be required for future manufacturing.This study uses seasonal trend forecasting and exponential smoothing of the time series forecasting method,and combining neural network with seasonal indexes analysis to conduct the sales forecasting research.The result is calculated and verified with the actual sales value in 2017 by the average absolute error percentage analysis.The results of exponential smoothing method is closest to the actual sales value,as to provide the enterprise with reference.
Lutz, Ronny Bernd. "The search for substellar companions to subdwarf B stars in connection with evolutionary aspects." Doctoral thesis, 2011. http://hdl.handle.net/11858/00-1735-0000-0006-B53E-1.
Full textVanderVennen, Robert E., Stanley Carlson, William V. Rowe, and Heather Marsman. "Perspective vol. 10 no. 2 (Feb 1976)." 2013. http://hdl.handle.net/10756/251334.
Full textVandenberg, Natasha, and Robert Sweetman. "Perspective vol. 35 no. 1 (Jan 2001)." 2013. http://hdl.handle.net/10756/251195.
Full textVanderBerg, Natasja, and Robert Sweetman. "Perspective vol. 35 no. 1 (Jan 2001)." 2001. http://hdl.handle.net/10756/277684.
Full textJoldersma, Clarence W., Roseanne Lopers Sweetman, Beilen Aileen Van, Henriette Thompson, and Bernard Zylstra. "Perspective vol. 15 no. 2 (Apr 1981)." 2013. http://hdl.handle.net/10756/251299.
Full textCarvill, Robert Lee, Mary Baumgartner, R. W. Bruinsma, and Andy den Otter. "Perspective vol. 5 no. 5 (Nov 1971)." 2013. http://hdl.handle.net/10756/251227.
Full textBannwitz, Sven. "C-2-Substituierte Derivate des 8-Hydroxy-naphthol[2,3-b]thiophen-4,9-dions als potenzielle Antipsoriatika: Synthese und biologische Evaluierung /." 2005. http://www.gbv.de/du/services/toc/bs/504716190.
Full textZuse, Anne. "Neue niedermolekulare Inhibitoren der Tubulinpolymerisation : Synthese und In-vitro-Prüfung von 9-Benzyliden-naphtho[2,3-b]thiophen-4(9H)-onen /." 2005. http://www.gbv.de/du/services/toc/bs/506320685.
Full textGary, Duim, Bernard Zylstra, and George Vandervelde. "Perspective vol. 17 no. 4 (Oct 1983)." 2013. http://hdl.handle.net/10756/251283.
Full textKuo, Szu-Chi, and 郭思琦. "A Study and Performance Practices on Sergei Rachmaninoff's Sonata No. 2 in B-flat Minor, Op. 36." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/64183449139542098539.
Full text國立臺北教育大學
音樂學系碩士班
103
Sergei Rachmaninoff (1873-1943) was an outstanding Russian musician in the late nineteenth century. Meanwhile, he was a very famous composer, conductor, and pianist ever. Although Rachmaninoff was from an upper class family, his life was still full of twists and turns. He experienced family broken, wars, the ups and downs in his composition career which all made Rachmaninoff’s music presents the feeling of pensive. This thesis will discuss Rachmaninoff’s piano sonata No.2 Op.36 . The different versions, background history, musical analysis of this music piece will be presented in the content. How this piece became a form of cyclic work and where to find the bell effects in this piano sonata were included in this thesis. Furthermore, the author provides the interpretations of this work by the author’s own experience as a piano performer. There are three movements in Piano Sonata No. 2 Op. 36. In the exposition of the first movement, there are three important motives in the first theme. Those three motives will be used in different forms and shapes in this sonata. Especially, in the second movement, the melody of Dies Irae is hidden in the beginning of the section A. The third movement is a sonata form without development part. In conclusion, Rachmaninoff’s Piano Sonata No. 2 Op. 36 is worth researching because of its musical constructions, development of musical motives, and harmony.
Pitt, Clifford C., Bruce Clemenger, and John R. A. Mayer. "Perspective vol. 22 no. 2 (Apr 1988)." 2013. http://hdl.handle.net/10756/251255.
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