Relevant bibliographies by topics / Serine recombinase

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Serine recombinase'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Serine recombinase.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Serine recombinase"

1

Marshall Stark, W., Martin R. Boocock, Femi J. Olorunniji, and Sally-J. Rowland. "Intermediates in serine recombinase-mediated site-specific recombination." Biochemical Society Transactions 39, no. 2 (2011): 617–22. http://dx.doi.org/10.1042/bst0390617.

Full text
Abstract:
Site-specific recombinases are enzymes that promote precise rearrangements of DNA sequences. They do this by cutting and rejoining the DNA strands at specific positions within a pair of target sites recognized and bound by the recombinase. One group of these enzymes, the serine recombinases, initiates strand exchange by making double-strand breaks in the DNA of the two sites, in an intermediate built around a catalytic tetramer of recombinase subunits. However, these catalytic steps are only the culmination of a complex pathway that begins when recombinase subunits recognize and bind to their
APA, Harvard, Vancouver, ISO, and other styles
2

Rice, Phoebe A., Kent W. Mouw, Sherwin P. Montaño, Martin R. Boocock, Sally-J. Rowland, and W. Marshall Stark. "Orchestrating serine resolvases." Biochemical Society Transactions 38, no. 2 (2010): 384–87. http://dx.doi.org/10.1042/bst0380384.

Full text
Abstract:
A remarkable feature of the serine resolvases is their regulation: the wild-type enzymes will catalyse intra- but not inter-molecular recombination, can sense the relative orientation of their sites and can exchange strands directionally, despite the fact that there is no net release of chemical bond energy. The key to this regulation is that they are only active within a large intertwined complex called the ‘synaptosome’. Because substrate topology greatly facilitates (or, in other cases, inhibits) formation of the synaptosome, it acts as a ‘topological filter’. Within the defined topology of
APA, Harvard, Vancouver, ISO, and other styles
3

Mouw, Kent W., Sally-J. Rowland, Mark M. Gajjar, Martin R. Boocock, W. Marshall Stark, and Phoebe A. Rice. "Architecture of a Serine Recombinase-DNA Regulatory Complex." Molecular Cell 30, no. 2 (2008): 145–55. http://dx.doi.org/10.1016/j.molcel.2008.02.023.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Van Duyne, Gregory D., and Karen Rutherford. "Large serine recombinase domain structure and attachment site binding." Critical Reviews in Biochemistry and Molecular Biology 48, no. 5 (2013): 476–91. http://dx.doi.org/10.3109/10409238.2013.831807.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Gaj, T., A. C. Mercer, C. A. Gersbach, R. M. Gordley, and C. F. Barbas. "Structure-guided reprogramming of serine recombinase DNA sequence specificity." Proceedings of the National Academy of Sciences 108, no. 2 (2010): 498–503. http://dx.doi.org/10.1073/pnas.1014214108.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Keenholtz, Ross A., Sally-J. Rowland, Martin R. Boocock, W. Marshall Stark, and Phoebe A. Rice. "Structural Basis for Catalytic Activation of a Serine Recombinase." Structure 19, no. 6 (2011): 799–809. http://dx.doi.org/10.1016/j.str.2011.03.017.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Rutherford, Karen, Kushol Gupta, and Gregory Van Duyne. "Solution Scattering Studies of Large Serine Recombinase-DNA Complexes." Biophysical Journal 104, no. 2 (2013): 368a. http://dx.doi.org/10.1016/j.bpj.2012.11.2046.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Bibb, Lori A., Maria I. Hancox та Graham F. Hatfull. "Integration and excision by the large serine recombinase φRv1 integrase". Molecular Microbiology 55, № 6 (2005): 1896–910. http://dx.doi.org/10.1111/j.1365-2958.2005.04517.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Sirk, Shannon J., Thomas Gaj, Andreas Jonsson, Andrew C. Mercer, and Carlos F. Barbas. "Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants." Nucleic Acids Research 42, no. 7 (2014): 4755–66. http://dx.doi.org/10.1093/nar/gkt1389.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Shao, Min, Shashi Kumar, and James G. Thomson. "Precise excision of plastid DNA by the large serine recombinase Bxb1." Plant Biotechnology Journal 12, no. 3 (2013): 322–29. http://dx.doi.org/10.1111/pbi.12139.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Serine recombinase"

1

Malla, Sunir K. "Using site-specific serine recombinases as tools for chromosome engineering." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430624.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Kobir, Ahasanul. "Physiological roles of Eukaryotic Hanks type Ser/Thr kinase in transition to stationary phase in Bacillus subtilis." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00911812.

Full text
Abstract:
Bacillus subtilis is the model organism for low GC Gram-positive bacteria and is of great biotechnological interest. Protein phosphorylation is an important regulatory mechanism in bacteria and it has not been extensively studied yet. Recent site-specific phosphoproteomic studies identified a large number of novel serine/threonine phosphorylation sites in B. subtilis, including a) two transition phase global gene regulators DegS and AbrB and b) RecA, that plays a major role in double-strand break repair and DNA recombination. .B. subtilis disposes of several putative Ser/Thr kinases like PrkA,
APA, Harvard, Vancouver, ISO, and other styles
3

Marcello, Matthew R. "Analysis of recombinant human prostasin carrying a serine active site mutation." Honors in the Major Thesis, University of Central Florida, 2003. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/325.

Full text
Abstract:
This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf.edu/Systems/DigitalInitiatives/DigitalCollections/InternetDistributionConsentAgreementForm.pdf You may also contact the project coordinator, Kerri Bottorff, at kerri.bottorff@ucf.edu for more information.<br>Bachelors<br>Health and Public Affairs<br>Molecular Biology and Microbiology
APA, Harvard, Vancouver, ISO, and other styles
4

Santos, Juliete Vitorino dos. "Expressão e purificação da forma recombinante dos Inibidores de Serino Peptidase ISP1 e ISP2 de Leishmania infantum chagasi." reponame:Repositório Institucional da UFABC, 2017.

Find full text
Abstract:
Orientadora: Profª Drª Márcia Aparecida Sperança<br>Dissertação (mestrado) - Universidade Federal do ABC, Programa de Pós-Graduação em Biossistemas, 2017.<br>A leishmaniose visceral, causada pelos parasitas das espécies Leishmania infantum e Leishmania donovani, do Velho Mundo, e pela Leishmania infantum chagasi, do Novo Mundo, é uma doença infecciosa e letal se não for tratada. O número de casos desta doença está aumentando no Estado de São Paulo. Uma vez diagnosticada, o tratamento para a leishmaniose visceral tem efeitos colaterais importantes, além da ocorrência de parasitas resistentes ao
APA, Harvard, Vancouver, ISO, and other styles
5

Benchabane, Meriem. "Modifications post-traductionnelles d'une serpine humaine recombinante exprimée chez les plantes." Thesis, Université Laval, 2007. http://www.theses.ulaval.ca/2007/24868/24868.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Benchabane, Meriem. "Modifications post-traductionnelles d’une serpine humaine recombinante exprimée chez les plantes." Rouen, 2007. http://www.theses.fr/2007ROUES020.

Full text
Abstract:
Les plantes ont la capacité de produire des protéines recombinantes mais des problèmes de N-glycosylation et de protéolyse persistent. Afin d’établir l’impact de la localisation sur la stabilité et la glycosylation d'une protéine recombinante, nous avons exprimé l’inhibiteur de protéase α1-antichymotrypsine (AACT) humaine dans quatre compartiments (RE, vacuole, apoplasme et cytosol) de cellules de tabac en culture. Le produit obtenu s'est avéré être plus hétérogène au sein du système de sécrétion, en raison d'une maturation de la N-glycosylation et d'une maturation protéolytique. Inversement,
APA, Harvard, Vancouver, ISO, and other styles
7

Eilerts, Diane. "Recombinant Expression and Potential Autocatalysis of Aedes aegypti Trypsin-Like Serine Proteases (AaSPII and AaSPIV)." Thesis, San Jose State University, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10284010.

Full text
Abstract:
<p> <i>Aedes aegypti</i> mosquitoes can be found globally in tropical and subtropical urban areas and spread Zika, Dengue fever, yellow fever, and Chikungunya viruses. Current vector control methods are limited and nonspecific. The female <i>Ae. aegypti</i> mosquito uses blood meal proteins to obtain nutrients required for oogenesis; inhibition of the midgut trypsin-like serine proteases responsible for blood meal digestion may provide a novel method of vector control. <i>Ae. aegypti</i> blood meal digestion is complex and the role of uncharacterized serine proteases in blood digestion is uncl
APA, Harvard, Vancouver, ISO, and other styles
8

Telli, Ilkin Ece. "Determination Of Metabolic Bottlenecks Using Reaction Engineering Principles In Serine Alkaline Protease Production By Recombinant Bacillus Species." Master's thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/2/12605227/index.pdf.

Full text
Abstract:
In this study, firstly, bioprocess characteristics for Serine Alkaline Protease (SAP) production, using recombinant Bacillus subtilis carrying pHV1431::subC, were examined. The cell concentration, substrate concentration, SAP activity and SAP synthesis rate profiles demonstrated that the system reaches to a steady state in terms of cell growth and SAP synthesis between t=15-25 h, therefore, this time interval is appropriate to employ both metabolic flux analysis and metabolic control analysis, which apply strictly to steady state systems. After that, three separate perturbations were intr
APA, Harvard, Vancouver, ISO, and other styles
9

Andrade, Regina Aparecida de. "Desenvolvimento de Vioserpina para estudo de especificidade e inibição da calicreína tecidual humana 5 recombinante, utilizando mutantes da vioserpina." reponame:Repositório Institucional da UFABC, 2017.

Find full text
Abstract:
Orientador: Prof. Dr. Luciano Puzer<br>Dissertação (mestrado) - Universidade Federal do ABC, Programa de Pós-Graduação em Biossistemas, São Bernardo do Campo, 2017.<br>Serpina é o nome dado à superfamília de proteínas com uma vasta diversidade de funções biológicas, que tem como principal característica a inibição irreversível de serino proteases. A característica estrutural mais marcante das serpinas é a presença de uma alça na sua porção C-terminal, composta por 20 aminoácidos denominados alça do centro reativo (RCL). A RCL é a região da serpina que se liga covalentemente ao sítio ativo da s
APA, Harvard, Vancouver, ISO, and other styles
10

Rascon, Alberto, Johnathon Gearin, Jun Isoe, and Roger Miesfeld. "In vitro activation and enzyme kinetic analysis of recombinant midgut serine proteases from the Dengue vector mosquito Aedes aegypti." BioMed Central, 2011. http://hdl.handle.net/10150/610098.

Full text
Abstract:
BACKGROUND:The major Dengue virus vector Aedes aegypti requires nutrients obtained from blood meal proteins to complete the gonotrophic cycle. Although bioinformatic analyses of Ae. aegypti midgut serine proteases have provided evolutionary insights, very little is known about the biochemical activity of these digestive enzymes.RESULTS:We used peptide specific antibodies to show that midgut serine proteases are expressed as zymogen precursors, which are cleaved to the mature form after blood feeding. Since midgut protein levels are insufficient to purify active proteases directly from blood fe
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Serine recombinase"

1

Perry, Dennis. The Recombinant Mystery of Frankenstein. Edited by Thomas Leitch. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199331000.013.8.

Full text
Abstract:
Mary Shelley’s Frankenstein, itself adapted from several sources, has triggered a never-ending series of film adaptations, each exploring the meaning of human life through the evolving landscapes of cultural and technological development. Adapted in James Whale’s Frankenstein as a figure of both horror and deep pathos, the monster and his creator have played a pivotal role in the development of the cinema of gothic horror, borrowing along the way from a wide array of genres as different as surrealism, slapstick comedy, and the Western. This basic story of human fears and desires has become the
APA, Harvard, Vancouver, ISO, and other styles
2

James, Philip. The natural environment. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198827238.003.0004.

Full text
Abstract:
As urbanization occurs in a particular location, so there are changes to the natural environment. Habitats become fragmented. Disturbance increases. Species diversity is often reduced. While some habitats are lost, other new ones are created. New combinations of plants and animals, occurring as recombinant communities, replace natural communities. Community structure is simplified, as is succession. The result is a series of habitats and communities that are unlike those found outside urban environments. Many of the normal rules of ecology seem not to apply in urban environments as humans modi
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Serine recombinase"

1

Marshall Stark, W. "The Serine Recombinases." In Mobile DNA III. ASM Press, 2015. http://dx.doi.org/10.1128/9781555819217.ch3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Smith, Margaret C. M. "Phage-encoded Serine Integrases and Other Large Serine Recombinases." In Mobile DNA III. ASM Press, 2015. http://dx.doi.org/10.1128/9781555819217.ch11.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Johnson, Reid C. "Site-specific DNA Inversion by Serine Recombinases." In Mobile DNA III. ASM Press, 2015. http://dx.doi.org/10.1128/9781555819217.ch9.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Baumgart, Florian, Clara Aicart-Ramos, and Ignacio Rodriguez-Crespo. "Preparation and Assay of Recombinant Serine Racemase." In Methods in Molecular Biology. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-331-8_24.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Olorunniji, Femi J., Christine Merrick, Susan J. Rosser, Margaret C. M. Smith, W. Marshall Stark, and Sean D. Colloms. "Multipart DNA Assembly Using Site-Specific Recombinases from the Large Serine Integrase Family." In Methods in Molecular Biology. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7169-5_19.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Bell, Christopher W., Victoria A. Roberts, Karen-Beth G. Scholthof, Guisheng Zhang, and Alexander E. Karu. "Recombinant Antibodies to Diuron." In ACS Symposium Series. American Chemical Society, 1995. http://dx.doi.org/10.1021/bk-1995-0586.ch004.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Fowler, Tim. "Recombinant β-Glucosidase ofTrichoderma reesei." In ACS Symposium Series. American Chemical Society, 1993. http://dx.doi.org/10.1021/bk-1993-0516.ch019.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Lee, Heather A., Gary Wyatt, Stephen D. Garrett, Maria C. Yanguela, and Michael R. A. Morgan. "Recombinant Antibodies Against Haptenic Mycotoxins." In ACS Symposium Series. American Chemical Society, 1995. http://dx.doi.org/10.1021/bk-1995-0586.ch002.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Kramer, K., and B. Hock. "Recombinant Antibodies for Agrochemicals: Evolutionary Optimization." In ACS Symposium Series. American Chemical Society, 2007. http://dx.doi.org/10.1021/bk-2007-0966.ch010.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Coppella, Steven J., Gregory F. Payne, and Neslihan DelaCruz. "Secondary Concerns of Recombinant Microorganism Processing." In ACS Symposium Series. American Chemical Society, 1991. http://dx.doi.org/10.1021/bk-1991-0477.ch001.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Serine recombinase"

1

Christensen, C., H. Arup, and R. T. Hill. "Corrosion Monitoring in Wet Sour Gas by Use of Hydrogen Permeation Probes." In CORROSION 1989. NACE International, 1989. https://doi.org/10.5006/c1989-89477.

Full text
Abstract:
Abstract Hydrogen is inevitably formed at corroding metal surfaces in oxygen free environments such wet sour gas or sour crude oil. Part of the hydrogen becomes absorbed into the metal substrate and once into the steel the hydrogen may recombine at phase boundaries and non metallic inclusions to cause blistering or collect at sites of high stresses where it interferes with the integrety of the matrix thereby resulting in a hydrogen embrittlement type of cracking. Monitoring of the hydrogen activity at the corroding surface can be accomplished using a sealed Devanathan cell with a steel membran
APA, Harvard, Vancouver, ISO, and other styles
2

Ny, T., L. Hansson, and B. Åstedt. "ISOLATION OF cDNA FOR TYPE-2 PLASMINOGEN ACTIVATOR INHIBITOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642855.

Full text
Abstract:
The placental type plasminogen activator inhibitor (PAI-2) has been purified from extracts of human placenta and from a histiocytic lymphoma cell line. It is mainly an uPA inhibitor but it also inhibits the two-chain form of tPA.In order to determine the factors regulating PAI-2 gene expression and thereby clarify the physiological role of PAI-2 we have undertaken the molecular cloning of PAI-2 cDNA. A λgt11 expression library prepared from placental mRNA, was screened, immunologically using a monoclonal antibody probe developed against PAI-2 purified from human placenta. When 1.7×105 recombin
APA, Harvard, Vancouver, ISO, and other styles
3

Karelina, K. V., R. B. Bayandin, and V. A. . Ternovoi. "PRODUCTION OF A FRAGMENT OF RECOMBINANT TICK PROTECTIVE ANTIGEN SERPIN IPIS-1, RCL-LOOP DOMAIN, OF IXODES PERSULCATUS TICKS." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-87.

Full text
Abstract:
Infections carried by ticks cause significant damage to livestock production, infections lead to loss of productivity, weakened immunity, allergic reactions, weight loss, and in severe cases death. When bitten, ticks produce a number of proteins — tick defense antigens — that facilitate the tick’s feeding on the host and thus facilitate the transmission of the infections they carry. Some of the tick protective antigens are serpins, a promising target for animal immunization and infection control. In studies, serpins from tick saliva have been shown to interact with host proteins while reducing
APA, Harvard, Vancouver, ISO, and other styles
4

Ashok Kumar, A., Margaret Insley, Jay Gambee, Sharon J. Busby, and Kathleen L. Berkner. "SITE SPECIFIC MUTAGENESIS WITHIN THE GLA-DOMAIN OF HUMAN FACTOR IX." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644079.

Full text
Abstract:
Factor IX, a plasma protein, plays a critical role in blood coagulation. The biological activity of factor IX as well as several other plasma proteins depends on the presence of gamma-carboxy glutamic acid (Gla) residues in their amino terminal region. In vitro mutagenesis has been used to selectively replace Gla residues of factor IX with aspartic acid (Asp) residues in order to establish the contribution of individual as well as paired Gla residues to the normal functioning of the protein. These substitutions were made at positions 7, 15, 20 and 26 in human factor IX. In addition, residue nu
APA, Harvard, Vancouver, ISO, and other styles
5

Qiu, Weiguo, Arjun Stokes, Joseph Cappello, and Xiaoyi Wu. "Electrospinning of Recombinant Protein Polymer Nanofibers." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206352.

Full text
Abstract:
Structural proteins often in the form of micro and nanofibers, constituting most of intra- and extracellular matrix (ECM), are the fundamental building blocks of life [1]. Recent efforts to replace diseased or damaged tissues and organs have resulted in the molecular design and genetic engineering of recombinant proteins, and the advent of new technology for fabricating structural proteins into micro-/nanofibrous scaffolds, hoping to resemble some or all the characteristics of ECM structure and function. The fabrication of such an ECM mimic may be an important step in engineering a functional
APA, Harvard, Vancouver, ISO, and other styles
6

Teng, Weibing, Yiding Huang, Joseph Cappello, and Xiaoyi Wu. "Mechanical and In-Vitro Cell Compatibility Properties of Silk-Elastinlike Protein-Based Biomaterial." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13141.

Full text
Abstract:
A series of genetically engineered recombinant silk-elastinlike proteins (SELPs) have been produced by combining polypeptide sequences derived from native silk of superior mechanical strength and elastin that is extremely durable and resilient. They have displayed a set of outstanding properties such as good biocompatibility and controllable biodegradation rates. In the study, we characterized the mechanical property of genetically engineered, recombinant silk-elastinlike protein copolymer, SELP-47K, under physical and chemical treatments. The biocompatibility of the SELP-47K was also evaluate
APA, Harvard, Vancouver, ISO, and other styles
7

Berkner, K. L., S. J. Busby, J. Gambee, and A. Kumar. "EXPRESSION IN MAMMALIAN CELLS OF FUSION PROTEINS BETWEEN HUMAN FACTORS IX AND VII." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643568.

Full text
Abstract:
The vitamin K-dependent plasma proteins demonstrate remarkable similarities in their structures: all have multiple domains in common and extensive homology is observed within many of these domains. In order to investigate the structure-function relationship of these proteins, we have interchanged domains of one protein (factor IX) with that of another (factor VII) and have compared the expression of these fusion proteins with recombinant and native factors IX and VII. Oligonucleotide-directed mutagenesis was used to generate four fusion proteins: factor IX/VII-1, which contains the factor IX l
APA, Harvard, Vancouver, ISO, and other styles
8

de La Cadena, R. A., D. Flores, C. F. Scott, et al. "RECOMBINANT ALPHA-1-ANTITRYPSIN PITTSBURGH ATTENUATES EXPERIMENTAL GRAM-NEGATIVE SEPTICEMIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644242.

Full text
Abstract:
Gram-negative septicemia is known to be associated with activation of the contact system and disseminated intravascular coagulation. Alpha-l-antitryosin-Pittsburgh (AT-P), a naturally occurring lethal nutation (358Met →&gt; Arg) is a potent inhibitor of all the contact enzymes as well as the coagulation enzyme, thrombin. We hypothesized that the administration of AT-P might modulate the course of gram-negative sepsis. The pig was selected as the animal model of choice since its fibrinolytic, kinin-forming, and coagulation systems are similar to man as well as its response to endotoxin. Young p
APA, Harvard, Vancouver, ISO, and other styles
9

Carrell, R. W., P. D. Christey, and D. R. Boswell. "SERPINS: ANTITHROMBIN AND OTHER INHIBITORS OF COAGULATION AND FIBRINOLYSIS. EVIDENCE FROM AMINO ACID SEQUENCES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642896.

Full text
Abstract:
A number of the key inhibitors of coagulation and fibrinolysis have recently been shown to be members of the same superfamily of serine protease inhibitors, the serpins. The archetypes of the group are alpha-l-antitrypsin and antithrombin and it includes antiplasmin, C1-inhibitor, heparin cofactor II and the newly recognised inhibitors of plasminogen activators and activated Protein C. Alignment of their structures shows that they have the same skeletal three-dimensional conformation and, by inference, the same general function mechanisms.The serpins have a reactive centre, primarily dependent
APA, Harvard, Vancouver, ISO, and other styles
10

Sas, G. "DEFECTS IN SERINE PROTEASE INHIBITORS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643714.

Full text
Abstract:
Several serine protease inhibitorsof plasma inhibit the activated coagulation enzymes but only antithrombin III(AT-III)and heparin cofactor II (HC-II) are implicated in the pathogenesisof the familial thrombosis. Since thefirst publication (1965) many thrombophilic families with reduced AT-III synthesis have been investigated. These studies have proved that the disorder is associated with a high risk forvenous thrombosis and the inheritanceis autosomal dominant. The AT-III activity in the plasma of the affected patients is about 50% of the normalvalue.In recent years the heterogeneity of the i
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Serine recombinase"

1

นุชประยูร, อิศรางค์, มณฑน์มาศ สุนทราวัฒน์ та ธัญณิชา อ่อนดี. การศึกษาโปรตีน ที่สำคัญในพิษงูแมวเซาเพื่อนำมาดัดแปลงใช้ประโยชน์ทางการแพทย์ : รายงานการวิจัยฉบับสมบูรณ์. จุฬาลงกรณ์มหาวิทยาลัย, 2009. https://doi.org/10.58837/chula.res.2009.23.

Full text
Abstract:
ปัญหางูพิษกัดเป็นปัญหาทางสาธารณะสุขที่สำคัญของประเทศไทย หนึ่งในงูพิษที่สำคัญในไทยคืองูแมวเซา (Daboia russellii siamensis) งูชนิดนี้พบมากในแถบภาคกลางและภาคตะวันออกของไทย ผู้ที่ถูกงูชนิดนี้กัด มักมีอาการทางระบบเลือด และภาวะไตวายเฉียบพลัน ซึ่งเป็นสาเหตุสำคัญที่ทำให้ผู้ที่ถูกงูแมวเซากัดเสียชีวิต ในปัจจุบันความรู้เกี่ยวกับกลไกการเกิดพิษหลังถูกงูแมวเซากัด รวมทั้งโปรตีนสำคัญในพิษงูแมวเซาที่อาจมีประโยชน์ทางการแพทย์ ยังไม่มีการศึกษาอย่างแน่ชัด การศึกษาองค์ประกอบของพิษงูแมวเซาในเชิงลึก จะช่วยให้เข้าใจกลไกการเกิดพิษ นำไปสู่การรักษาที่มีประสิทธิภาพที่ดีขึ้น พร้อมทั้งอาจนำความรู้ที่ได้ไปใช้ประโยชน์ในทางการ
APA, Harvard, Vancouver, ISO, and other styles
2

Norelli, John L., Moshe Flaishman, Herb Aldwinckle, and David Gidoni. Regulated expression of site-specific DNA recombination for precision genetic engineering of apple. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7587214.bard.

Full text
Abstract:
Objectives: The original objectives of this project were to: 1) evaluate inducible promoters for the expression of recombinase in apple (USDA-ARS); 2) develop alternative selectable markers for use in apple to facilitate the positive selection of gene excision by recombinase (Cornell University); 3) compare the activity of three different recombinase systems (Cre/lox, FLP/FRT, and R/RS)in apple using a rapid transient assay (ARO); and 4) evaluate the use of recombinase systems in apple using the best promoters, selectable markers and recombinase systems identified in 1, 2 and 3 above (Collabor
APA, Harvard, Vancouver, ISO, and other styles
3

Galili, Gad, and Alan Bennett. Role of Molecular Chaperone in Wheat Storage Protein Assembly. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604926.bard.

Full text
Abstract:
Following sequestration into the ER, wheat gliadins assemble into complexes that initiate the formation of protein bodies. In the present work we have characterized the DNA sequence and regulation of expression of a plant BiP and also studied its interaction with wheat storage proteins as well as its role in the maturation of these storage proteins. In the Israeli lab, immunoprecipitation studies were made using anti BiP and anti storage proteins sera, both in wheat and in transgenic tobacco plants expressing a wheat gliadin storage proteins. In both cases, we could show that BiP interacts wit
APA, Harvard, Vancouver, ISO, and other styles
4

Leitner, Gabriel, and Naomi Balaban. Novel Immunotherapeutic Agent for the Treatment and Prevention of Staphylococcal Mastitis in Dairy Cows. United States Department of Agriculture, 2009. http://dx.doi.org/10.32747/2009.7709880.bard.

Full text
Abstract:
Staphylococci are the most common and costly mammary disease of dairy cattle worldwide. TRAP, a membrane associated 167AA protein, is highly conserved among staphylococci. The aims of this study were to test the safety and efficacy of recombinant TRAP (rTRAP) vaccine in dairy animals. The vaccine was safe as 2-3 subcutaneous injections of rTRAP (54–100μg) with adjuvant ISA 206 to cows and goats did not lead to any abnormal symptoms of sensitivity to the vaccine. The rTRAP vaccine was immunogenic and caused the induction of a humoral immune response that remained high for at least 160 days post
APA, Harvard, Vancouver, ISO, and other styles
5

Leitner, Gabriel, and Naomi Balaban. Novel Immunotherapeutic Agent for the Treatment and Prevention of Staphylococcal Mastitis in Dairy Cows. United States Department of Agriculture, 2009. http://dx.doi.org/10.32747/2009.7695866.bard.

Full text
Abstract:
Staphylococci are the most common and costly mammary disease of dairy cattle worldwide. TRAP, a membrane associated 167AA protein, is highly conserved among staphylococci. The aims of this study were to test the safety and efficacy of recombinant TRAP (rTRAP) vaccine in dairy animals. The vaccine was safe as 2-3 subcutaneous injections of rTRAP (54–100μg) with adjuvant ISA 206 to cows and goats did not lead to any abnormal symptoms of sensitivity to the vaccine. The rTRAP vaccine was immunogenic and caused the induction of a humoral immune response that remained high for at least 160 days post
APA, Harvard, Vancouver, ISO, and other styles
6

Boisclair, Yves R., Alan W. Bell, and Avi Shamay. Regulation and Action of Leptin in Pregnant and Lactating Dairy Cows. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7586465.bard.

Full text
Abstract:
The original project had four specific objectives: (1) To complete the development of a radioimmunoassay for bovine leptin; (2) To characterize the leptin system in lactating dairy cows during the transition from pregnancy to lactation; (3) To identify endocrine factors regulating the production of leptin by bovine adipose tissue; (4) To study the actions of leptin on bovine adipose and mammary tissues in vitro. However, BARD funded only the development of the bovine leptin RIA (Objective 1) for a single year. This report describes our work in completing this objective. Leptin, a protein hormo
APA, Harvard, Vancouver, ISO, and other styles
7

Grumet, R., J. Burger, Y. Tadmor, et al. Cucumis fruit surface biology: Genetic analysis of fruit exocarp features in melon (C. melo) and cucumber (C. sativus). United States-Israel Binational Agricultural Research and Development Fund, 2020. http://dx.doi.org/10.32747/2020.8134155.bard.

Full text
Abstract:
The fruit surface (exocarp) is a unique tissue with multiple roles influencing fruit growth and development, disease susceptibility, crop yield, post-harvest treatments, shipping and storage quality, and food safety. Furthermore, highly visible exocarp traits are the consumer's first exposure to the fruit, serving to identify fruit type, variety, attractiveness, and market value. Cucurbit fruit, including the closely related Cucumis species, melon (C. melo) and cucumber (C. sativus), exhibit tremendous diversity for fruit surface properties that are not present in model species. In this projec
APA, Harvard, Vancouver, ISO, and other styles
8

Splitter, Gary, Zeev Trainin, and Yacov Brenner. Lymphocyte Response to Genetically Engineered Bovine Leukemia Virus Proteins in Persistently Lymphocytic Cattle from Israel and the U.S. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570556.bard.

Full text
Abstract:
The goal of this proposal was to identify proteins of BLV recognized by lymphocyte subpopulations and determine the contribution of these proteins to viral pathogenesis. Our hypothesis was that BLV pathogenesis is governed by the T-cell response and that the immune system likely plays an important role in controlling the utcome of infection. Our studies presented in ths final report demonstrate that T cell competency declines with advancing stages of infection. Dramatic differences were observed in lymphocyte proliferation to recombinant proteins encoded by BLV gag (p12, p15, and p24) and env
APA, Harvard, Vancouver, ISO, and other styles
9

Aharoni, Asaph, Zhangjun Fei, Efraim Lewinsohn, Arthur Schaffer, and Yaakov Tadmor. System Approach to Understanding the Metabolic Diversity in Melon. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7593400.bard.

Full text
Abstract:
Fruit quality is determined by numerous genetic factors that affect taste, aroma, ‎color, texture, nutritional value and shelf life. To unravel the genetic components ‎involved in the metabolic pathways behind these traits, the major goal of the project was to identify novel genes that are involved in, or that regulate, these pathways using correlation analysis between genotype, metabolite and gene expression data. The original and specific research objectives were: (1) Collection of replicated fruit from a population of 96 RI lines derived from parents distinguished by great diversity in frui
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Serine recombinase' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography