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1

KISSLING, E., P. WATTIAU, B. CHINA, et al. "B. anthracis in a wool-processing factory: seroprevalence and occupational risk." Epidemiology and Infection 140, no. 5 (2011): 879–86. http://dx.doi.org/10.1017/s0950268811001488.

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SUMMARYIn a Belgian wool-processing factory, living anthrax spores were found in raw goat hair and air dust, but confirmed anthrax cases had never been reported. Anthrax vaccines are not licensed nor recommended in Belgium. We conducted a B. anthracis seroprevalence study to investigate risk factors associated with positive serology and advise on protective measures. Overall 12·1% (8/66) employees were seropositive; 30% of persons processing raw goat hair and 20% of persons sorting raw goat hair were seropositive compared to 3% in less exposed jobs [adjusted prevalence ratio (aPR) 44·4, P=0·00
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2

Katusiime, Christine, and Andrew Kambugu. "Chronic genital ulcer disease with subsequent development of methicillin-resistant Staphylococcus aureus (MRSA) urethritis and bacteraemia in an HIV-seropositive person – a case observation." Southern African Journal of HIV Medicine 13, no. 1 (2012): 34–35. http://dx.doi.org/10.4102/sajhivmed.v13i1.158.

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HIV-seropositive persons are at increased risk of methicillin-resistant Staphylococcus aureus (MRSA). Genital ulcerative disease and sexually transmitted infection with subsequent MRSA infection in HIV-seropositive persons have been documented only once. We report a case of a 44-year-old man who presented to the Infectious Diseases Institute, Kampala, Uganda, with chronic genital ulcer disease and who subsequently developed MRSA urethritis and bacteraemia. This case also demonstrates that persistent genital ulcer disease in HIV-seropositive persons may be as a result of concurrent MRSA infecti
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3

Larsen, Christian P., Flavio Vincenti, Tzuyung D. Kou, et al. "Long-term Safety in Epstein–Barr Virus–Seropositive Kidney-only Transplant Recipients Treated With Belatacept in Clinical Practice: Final Study Results From the ENLiST Registry." Transplantation Direct 10, no. 6 (2024): e1644. http://dx.doi.org/10.1097/txd.0000000000001644.

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Background. Belatacept, a selective T-cell costimulation blocker, was associated with improved survival and renal function but also with a risk of posttransplant lymphoproliferative disorder (PTLD) in adult kidney transplant recipients in phase 3 trials. This registry examined long-term safety in Epstein–Barr virus (EBV)–seropositive kidney transplant recipients treated with belatacept. Methods. This US-based, prospective, voluntary, multicenter registry (Evaluating Nulojix Long-Term Safety in Transplant [ENLiST]) included adult EBV-seropositive kidney-only transplant recipients treated de nov
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Fikadu, Worku, Chala Dechassa, Zelalem Desalegn, Adisu Ewunetu, Matiyos Lema, and Adisu Tekle. "HIV seropositive disclosure and associated factors among adult HIV positive clients in public health facilities in East Wollega Zone, Oromia Regional State, Western Ethiopia." PLOS ONE 19, no. 10 (2024): e0305389. http://dx.doi.org/10.1371/journal.pone.0305389.

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Background Disclosure of HIV-seropositive is important for HIV prevention and maintenance of health for people living with HIV and the community at large. Although HIV seropositive disclosure is mandatory for access to care and treatment, there is a paucity of data in the study setting. Objective This study aimed to assess the magnitude of HIV Sero Positive Disclosure and associated factors among adult HIV positive clients in public health facilities in the east wollega zone, Oromia Regional State, Western Ethiopia, in 2023. Methods A facility-based cross-sectional study design was conducted a
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Anusha, Mekala, Rithvik Ramesh, Sundar Shanmugam, et al. "Camptocormia in a young man with anti-GAD-seropositive stiff-person syndrome." BMJ Case Reports 17, no. 8 (2024): e262122. http://dx.doi.org/10.1136/bcr-2024-262122.

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Stiff-person syndrome (SPS) usually manifests as an autoimmune neuromuscular disorder characterised by pronounced and advancing rigidity, primarily affecting the trunk and proximal muscles. There are various clinical subtypes like classic SPS (truncal stiffness, generalised rigidity and muscle spasms), partial SPS (stiff-limb syndrome) and uncommon forms including progressive encephalomyelitis with rigidity and myoclonus. Camptocormia, defined as forward flexion of the spine in the upright position that disappears in the supine position, without fixed deformity, has been described only in two
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Steven, BK. "Seropositive PERM associated with leucocytoclastic vasculitis." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 42, S1 (2015): S35—S36. http://dx.doi.org/10.1017/cjn.2015.164.

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Background: Progressive encephalomyelitis, rigidity, and myoclonus (PERM) is a variant stiff-person plus syndrome consisting of brainstem and pyrimidal dysfunction, muscular rigidity, stimulus-evoked spasms, and dysautonomia. Continuous motor-unit activity from ectopic anterior horn cell discharges underlies the myotomal hyperactivity. Case Report: A 51-year-old man with an 8-year history of “spasmodic” mid and low back pain presented with increasing stiffness, hyperekplexia-induced opisthotonus-like posturing, urinary retention, long-tract motor signs, and diplopia. He had a recent history of
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7

Goryoka, Grace W., Caitlin M. Cossaboom, Radhika Gharpure, et al. "One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020." Viruses 13, no. 9 (2021): 1813. http://dx.doi.org/10.3390/v13091813.

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Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from April–May 2020. We enrolled 37 dogs and 19 cats from 34 households. All oropharyngeal, nasal, and rectal swabs tested negative by rRT-PCR; one dog’s fur swabs (2%) tested positive by rRT-PCR at the first sampling. Among 47 pets with serological results, eight (17%) pets (four dogs, four cats) from 6/
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8

Hidayati, Rizqi Wahyu, and Dwi Kartika Rukmi. "Pengalaman Ibu Saat Pertama Kali Terdiagnosa HIV." Jurnal Penelitian Kesehatan "SUARA FORIKES" (Journal of Health Research "Forikes Voice") 11, no. 3 (2020): 287. http://dx.doi.org/10.33846/sf11313.

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Increasing number of HIV cases were worried. The new case was found increasing 39% in sixteen years. Indonesia had 150.296 cases. ARV program and screening were used to hold the cases. On the other hand, this program had difficulties to improve because of the stigma. Most of them did not want to share their diagnosis. Because of that, self-disclosure of HIV person was an interesting thing to catch up. This aim of the research was to know the meaning of self-disclosure for mother who had seropositive HIV in Victory Plus Yogyakarta Foundation. The method was qualitative study with phenomenology
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9

Lawrence, DN, JM Jason, JD Bouhasin, et al. "HTLV-III/LAV antibody status of spouses and household contacts assisting in home infusion of hemophilia patients." Blood 66, no. 3 (1985): 703–5. http://dx.doi.org/10.1182/blood.v66.3.703.703.

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Abstract Thirty-four adult and pediatric hemophilia A and B patients and 50 nonhemophilic members belonging to 28 families were enrolled in August 1984 in a study of human T cell lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) antibody status and T cell subpopulation numbers. All 50 household contacts, including three spouses of LAV antibody-positive adult hemophiliacs, were immunologically normal and serologically negative with respect to HTLV- III/LAV. Based on Western blot serologic testing of blood samples collected intermittently between July 1981 and August 19
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Lawrence, DN, JM Jason, JD Bouhasin, et al. "HTLV-III/LAV antibody status of spouses and household contacts assisting in home infusion of hemophilia patients." Blood 66, no. 3 (1985): 703–5. http://dx.doi.org/10.1182/blood.v66.3.703.bloodjournal663703.

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Thirty-four adult and pediatric hemophilia A and B patients and 50 nonhemophilic members belonging to 28 families were enrolled in August 1984 in a study of human T cell lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) antibody status and T cell subpopulation numbers. All 50 household contacts, including three spouses of LAV antibody-positive adult hemophiliacs, were immunologically normal and serologically negative with respect to HTLV- III/LAV. Based on Western blot serologic testing of blood samples collected intermittently between July 1981 and August 1984 from 3
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11

Intini, D., S. Scannicchio, V. Velucci, et al. "Anti-Amphiphysin-IgG-seropositive paraneoplastic syndrome: a rare cause of Stiff Person Syndrome." Parkinsonism & Related Disorders 134 (May 2025): 107481. https://doi.org/10.1016/j.parkreldis.2025.107481.

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12

Hinson, Shannon R., A. Sebastian Lopez-Chiriboga, James H. Bower, et al. "Glycine receptor modulating antibody predicting treatable stiff-person spectrum disorders." Neurology - Neuroimmunology Neuroinflammation 5, no. 2 (2018): e438. http://dx.doi.org/10.1212/nxi.0000000000000438.

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BackgroundGlycine receptor alpha-1 subunit (GlyRα1)-immunoglobulin G (IgG) is diagnostic of stiff-person syndrome (SPS) spectrum but has been reported detectable in other neurologic diseases for which significance is less certain.MethodsTo assess GlyRα1-IgGs as biomarkers of SPS spectrum among patients and controls, specimens were tested using cell-based assays (binding [4°C] and modulating [antigen endocytosing, 37°C]). Medical records of seropositive patients were reviewed.ResultsGlyRα1-IgG (binding antibody) was detected in 21 of 247 patients with suspected SPS spectrum (8.5%) and in 8 of 1
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13

Chia, Nicholas, Andrew McKeon, Eoin Flanagan, et al. "Stiff Person Syndrome Misdiagnosis: Clinical and Ancillary Testing Characteristics." Neurology 99, no. 23 Supplement 2 (2022): S12—S13. http://dx.doi.org/10.1212/01.wnl.0000903120.29940.d6.

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ObjectiveTo assess stiff person syndrome (SPS) misdiagnosis and identify factors differentiating SPS from non-SPS.BackgroundSPS is a heterogeneous immune-mediated central hyperexcitability disorder that is challenging to differentiate from alternative diagnoses.Design/MethodsPatients referred to the Mayo Autoimmune Neurology Clinic for SPS (01-Jul-2016 to 30-Jun-2021) were included. SPS diagnosis was defined as compatible clinical syndrome confirmed by an autoimmune neurologist and either serum positivity for high-titer GAD65-IgG (>20.0 nmol/L), glycine-receptor-IgG or amphiphysin-IgG (sero
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14

Sandu, Mihaela Luminita, Mariana Floricica Calin, and Mariana Violeta Fusea. "Self-esteem and unconditional acceptance of oneself, in HIV positive people." Technium Social Sciences Journal 41 (March 9, 2023): 147–68. http://dx.doi.org/10.47577/tssj.v41i1.8501.

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The present work entitled "Self-esteem and unconditional acceptance of oneself, in seropositive people", highlights the problem of real states, which seropositive people face, to situations and intercessions related to self-esteem. This followed the behavior of HIV positive people, attitudes towards other people or vis-à-vis their own lives. Self-esteem is an element of the self and refers to affective living, to the emotions that the individual experiences when referring to himself. It is a make-up of the cognitive scheme relating to oneself. The idea that self-esteem is one of the factors th
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BENCE, Angel Ricardo, María Celeste MORAN, Claudio Santiago CACCIATO, Javier SOTO, Silvina Elena GUTIERREZ, and Silvia Marcela ESTEIN. "Identification of a small-scale pig farm infected with Brucella suis linked to a clinical case of human brucellosis in Buenos Aires province, Argentina." FAVE Sección Ciencias Veterinarias 20, no. 1 (2021): 34–40. http://dx.doi.org/10.14409/favecv.v20i1.10055.

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Here we report a case of human brucellosis due to Brucella suis in a person who worked in a small-scale pig farm. The farm had no history of clinical brucellosis, and signs of the disease were not observed upon clinical examination of the animals. Serum from all the 3 boars, 16/22 sows and 9/25 gilts was obtained for serological examination by Buffered Plate Agglutination Test (BPAT), Rose Bengal Test (RBT) and Fluorescent Polarization Assay (FPA). Bacteriological culture and Direct Fluorescence Antibody Test (DFAT) were performed in tissue samples from a seropositive boar and a sow. Specific
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16

Al-Knawy, BA, M.-Elbagir K. Ahmed, S. Mirdad, A. ElMekki, and O. Al-Ammari. "Intrafamillial Clustering ofHelicobacter pyloriInfection in Saubi Arabia." Canadian Journal of Gastroenterology 14, no. 9 (2000): 772–74. http://dx.doi.org/10.1155/2000/952965.

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AIM: To study the pattern ofHelicobacter pyloriinfection among family members in the Saudi population.METHODS: A cross-sectional, population-based, seroepidemiological study of family members was undertaken in a Saudi population using salivaH pyloriimmunoglobulin (Ig) G antibodies (Helisal kit).RESULTS: A total of 42 families comprising 271 children and 84 parents were studied (355 subjects; mean age 23 years, SD 19 years) The overall frequencies ofH pyloriIgG antibodies in mothers, fathers and children were 67%, 64% and 23%, respectively. There was no significant difference in the infection r
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Lee, Min Young, Kok Pin Yong, Jae-Won Hyun, Su-Hyun Kim, Sang-Hyun Lee, and Ho Jin Kim. "Incidence of interattack asymptomatic brain lesions in NMO spectrum disorder." Neurology 95, no. 23 (2020): e3124-e3128. http://dx.doi.org/10.1212/wnl.0000000000010847.

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ObjectiveTo determine whether aquaporin-4 (AQP4) antibody–seropositive patients with neuromyelitis optica spectrum disorder (NMOSD) develop new asymptomatic brain lesions during the interattack period.MethodsOf 296 consecutive AQP4 antibody–seropositive patients in the NMOSD database of the National Cancer Center from May 2005 to November 2019, 145 patients, who had serial brain MRI scans over an interval of at least 1 year during relapse-free period after immunosuppressive therapy, with 370 longitudinally assessed brain MRI scans were included in this study. We retrospectively analyzed them f
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Kim, Haein, Joo hee jung, Jiwon Jung, et al. "1106. The incidence and risk factors associated with varicella zoster virus infection in kidney transplant recipients after 1-month acyclovir prophylaxis in a CMV preemptive therapy era." Open Forum Infectious Diseases 7, Supplement_1 (2020): S583—S584. http://dx.doi.org/10.1093/ofid/ofaa439.1292.

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Abstract Background Varicella zoster virus (VZV) infection is a well-known opportunistic infection in solid organ transplant recipients. Since the various strategies of the use of anti-herpetic drugs including ganciclovir or acyclovir have evolved, the epidemiology of VZV infection is changing. However, there are limited data on the recent incidence and risk factors of post-transplant VZV infection in popular preemptive ganciclovir era for CMV infection. We evaluated the incidence, risk factors and clinical characteristic of patients with development of post-transplant VZV infection in kidney
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Bran-Piedrahita, Lemy, Sergio Gómez-Molina, Alejandro Valencia-Arias, et al. "Access Barriers to Health Services Perceived by People Living With HIV and Their Families." Global Journal of Health Science 10, no. 3 (2018): 54. http://dx.doi.org/10.5539/gjhs.v10n3p54.

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INTRODUCCTION: The Human Immunodeficiency Virus (HIV) is a retrovirus that destroys the body's T cells. Its advanced stage is the Acquired Immune Deficiency Syndrome (AIDS), since its onset, it has been extensively studied because of an associated burden of morbidity and also to understand the access barriers to diagnostic tests and the required treatment. Objective: To understand the barriers to access health services as perceived by adults living with HIV and their families in the city of Medellín (Colombia).METHODOLOGY: A qualitative investigation by using historical-hermeneutical approach
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Arenal-Cruz, F., G. Jobson, E. Villanueva, and J. Zhu. "AB0313 UNDERSTANDING DISEASE PREVALENCE AND COMORBIDITY PROFILES AMONG SEROPOSITIVE AND SERONEGATIVE RHEUMATOID ARTHRITIS PATIENTS IN PUERTO RICO." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1340.2–1340. http://dx.doi.org/10.1136/annrheumdis-2023-eular.594.

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BackgroundPrevalence of rheumatoid factor (RF) and/or anti-cyclic citrullinated peptide antibody (ACPA) positivity in US patients with rheumatoid arthritis (RA) is around 70%[1]. Seropositive RA status, defined by positivity for RF and/or ACPA, is associated with poor disease prognosis[2].Little is known about the prevalence of RA, percentages of seropositive RA versus seronegative RA, and the comorbidity profile and infections of these patients in Puerto Rico (PR).ObjectivesTo estimate the prevalence of seropositive and seronegative RA in PR and to understand the demographic and clinical char
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Bosevska, Golubinka, Nikola Panovski, Eleni Dokić, and Violeta Grunevska. "RT-PCR Detection of HIV in Republic of Macedonia." Bosnian Journal of Basic Medical Sciences 8, no. 4 (2008): 350–55. http://dx.doi.org/10.17305/bjbms.2008.2896.

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The aim of the study was to detect HIV RNA in seropositive patients using RT-PCR method and thus, to establish PCR methodology in the routine laboratory works.The total of 33 examined persons were divided in two groups: 1) 13 persons seropositive for HIV; and 2) 20 healthy persons - randomly selected blood donors that made the case control group. The subjects age was between 25 and 52 years (average 38,5).ELFA test for combined detection of HIV p24 antigen and anti HIV-1 + 2 IgG and ELISA test for detection of antibodies against HIV-1 and HIV-2, were performed for each examined person. RNA fro
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Hu, Yang, Jeffrey A. Sparks, Susan Malspeis, et al. "Long-term dietary quality and risk of developing rheumatoid arthritis in women." Annals of the Rheumatic Diseases 76, no. 8 (2017): 1357–64. http://dx.doi.org/10.1136/annrheumdis-2016-210431.

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ObjectivesTo evaluate the association between long-term dietary quality, measured by the 2010 Alternative Healthy Eating Index, and risk of rheumatoid arthritis (RA) in women.MethodsWe prospectively followed 76 597 women in the Nurses' Health Study aged 30–55 years and 93 392 women in the Nurses' Health Study II aged 25–42 years at baseline and free from RA or other connective tissue diseases. The lifestyle, environmental exposure and anthropometric information were collected at baseline and updated biennially. Cumulative follow-up rates were more than 90% for both cohorts. The primary outcome
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Jain, Amita, Anuragani Verma, Suruchi Shukla, and Anil K. Verma. "Dynamics of anti-SARS-CoV-2 IgG antibodies over four months period during pandemic in health care workers." International Journal Of Community Medicine And Public Health 9, no. 5 (2022): 2149. http://dx.doi.org/10.18203/2394-6040.ijcmph20221232.

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Background: Person infected with Severe acute respiratory syndrome- coronavirus-2 (SARS-CoV-2) may develop virus specific IgG antibodies but antibody titers might decline over time, if antibody titer decline over time, chances of HCWs getting re-infected are higher.Methods: Here we assessed status of Anti SARS-CoV-2 antibodies in HCWs over a four months period by detection of anti-SARS-CoV-2-IgG antibodies using a semi-quantitative enzyme-linked immunosorbent assay (ELISA).Results: The present follow up study shows that during four months period sero-positivity in HCWs increased from 32% to 42
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Kiyong’a, Alice N., Elizabeth A. J. Cook, Nisreen M. A. Okba, et al. "Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Seropositive Camel Handlers in Kenya." Viruses 12, no. 4 (2020): 396. http://dx.doi.org/10.3390/v12040396.

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Middle East respiratory syndrome (MERS) is a respiratory disease caused by a zoonotic coronavirus (MERS-CoV). Camel handlers, including slaughterhouse workers and herders, are at risk of acquiring MERS-CoV infections. However, there is limited evidence of infections among camel handlers in Africa. The purpose of this study was to determine the presence of antibodies to MERS-CoV in high-risk groups in Kenya. Sera collected from 93 camel handlers, 58 slaughterhouse workers and 35 camel herders, were screened for MERS-CoV antibodies using ELISA and PRNT. We found four seropositive slaughterhouse
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Tiwari, Manoj, Binay Thakur, Zhenqing Shun, Sagar Khatiwada, and Sachee Bhattarai. "Subxiphoid thoracoscopic thymectomy in a young female with seropositive Myasthenia Gravis: A case report." Nepalese Journal of Cancer 8, no. 1 (2024): 71–75. http://dx.doi.org/10.3126/njc.v8i1.68241.

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Case: Myasthenia Gravis (MG) is an autoimmune disease that occurs at the neuromuscular junction and characterized by weakness of voluntary skeletal muscles which may be generalized or localized with an incidence of 4.1 to 30 cases per million person-years. MG is diagnosed clinically and by measuring the level of acetylcholine receptor antibodies, Muscle specific kinase antibodies and Low-density lipoprotein receptor related protein-4 antibodies. Patient is managed conservatively with cholinesterase inhibitor (pyridostigmine), prednisone, Mycophenolate mofetil and surgically by thymectomy. Here
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Chernokhaeva, L. L., G. B. Maikova, Yu V. Rogova, et al. "COMPARISON OF RESULTS OBTAINED BY ELISA AND NEUTRALIZATION TEST IN ASSESSING THE PROTECTION OF POPULATION FROM TICK-BORNE ENCEPHALITIS." Problems of Virology, Russian journal 63, no. 1 (2018): 36–40. http://dx.doi.org/10.18821/0507-4088-2018-63-1-36-40.

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The enzyme-linked immunosorbent assay (ELISA) and the neutralization test (NT) are often used to determine the level of seropositive population and to evaluate the immunogenicity of vaccines. ELISA provides information on the total pool of antiviral antibodies, while NT allows the antiviral protection level of a person to be estimated. It is assumed that the 1:100 titer in ELISA and the 1:10 titer in NT are protective. Obviously, the ratio of the total pool and virus neutralizing antibodies can vary as a result of natural immunization or vaccination. In this study, two methods were used to stu
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Leidi, Antonio, Amandine Berner, Roxane Dumont, et al. "Occupational risk of SARS-CoV-2 infection and reinfection during the second pandemic surge: a cohort study." Occupational and Environmental Medicine 79, no. 2 (2021): 116–19. http://dx.doi.org/10.1136/oemed-2021-107924.

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ObjectivesThis cohort study including essential workers, assessed the risk and incidence of SARS-CoV-2 infection during the second surge of COVID-19 according to baseline serostatus and occupational sector.MethodsEssential workers were selected from a seroprevalence survey cohort in Geneva, Switzerland and were linked to a state centralised registry compiling SARS-CoV-2 infections. Primary outcome was the incidence of virologically confirmed infections from serological assessment (between May and September 2020) to 25 January 2021, according to baseline antibody status and stratified by three
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Herring, Belinda L., Rose Tsui, Lorraine Peddada, Michael Busch, and Eric L. Delwart. "Wide Range of Quasispecies Diversity during Primary Hepatitis C Virus Infection." Journal of Virology 79, no. 7 (2005): 4340–46. http://dx.doi.org/10.1128/jvi.79.7.4340-4346.2005.

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ABSTRACT Hepatitis C virus (HCV) infections may be initiated by multiple infectious particles, resulting in a genetically heterogeneous viral population, or by a single particle, leading to a clonal population in the initial stage of infection. To determine which of these scenarios is most common, we evaluated the genetic diversity of HCV quasispecies in 12 seronegative subjects with primary infection following community exposures, six acutely infected recipients of HCV-seropositive blood transfusions and six seropositive individuals with infections of undetermined durations. RNA isolated from
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Bualert, Lertwut, Toon Ruang-areerate, Mathirut Mungthin, et al. "Incidence and persistence of asymptomatic Leishmania infection among HIV-infected patients in Trang province, Southern Thailand: A cohort study." PLOS Neglected Tropical Diseases 18, no. 10 (2024): e0012581. http://dx.doi.org/10.1371/journal.pntd.0012581.

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Leishmaniasis poses a significant health burden, particularly among immunocompromised patients. In Thailand, Leishmania infection caused by Leishmania martiniquensis and Leishmania orientalis lacks information about the incidence and risk factors among HIV-infected populations. This longitudinal cohort study aimed to investigate the incidence and persistence of Leishmania infection among HIV-infected individuals in an affected area, Trang Province, Southern Thailand. The study also identified risk factors associated with the incidence of Leishmania infection. The study enrolled 373 participant
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Cardoso, Mauro Nogueira, Waleska Teixeira Caiaffa, and Sueli Aparecida Mingoti. "AIDS incidence and mortality in injecting drug users: the AjUDE-Brasil II Project." Cadernos de Saúde Pública 22, no. 4 (2006): 827–37. http://dx.doi.org/10.1590/s0102-311x2006000400021.

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This paper presents AIDS incidence and mortality among injecting drug users (IDUs) reached by the AjUDE-Brasil II Project. From a cross-sectional survey, 478 IDUs were interviewed in three Brazilian cities: Porto Alegre, São José do Rio Preto, and Itajaí. The cohort was followed up in the Brazilian surveillance database for AIDS and mortality during 2000 and 2001. AIDS incidence was 1.1 cases per 100 person-years, and the mortality rate was 2.8 deaths per 100 person-years. AIDS cases only occurred in IDUs who reported ever having shared injecting equipment. Female gender (RR = 5.30), homelessn
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Muula, Adamson S., and Joseph M. Mfutso-Bengo. "When is Public Disclosure of HIV Seropositivity Acceptable?" Nursing Ethics 12, no. 3 (2005): 288–95. http://dx.doi.org/10.1191/0969733005ne790oa.

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HIV/AIDS is a major public health problem in Africa. Stigmatization, discrimination and lack of appropriate health care are among the commonest challenges that HIV infected persons and their families face. It has been suggested that among the tools available in the fight against stigmatization and discrimination is public disclosure of a person’s HIV seropositive status. While public disclosure of HIV status has a place in the fight against HIV and AIDS, especially by resulting in behavioural change among people who know of an HIV infected person, we argue that such disclosure also has potenti
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Cardinal, Marta Victoria, Gustavo Fabián Enriquez, Natalia Paula Macchiaverna, et al. "Long-term impact of a ten-year intervention program on human and canine Trypanosoma cruzi infection in the Argentine Chaco." PLOS Neglected Tropical Diseases 15, no. 5 (2021): e0009389. http://dx.doi.org/10.1371/journal.pntd.0009389.

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Background Interruption of domestic vector-borne transmission of Trypanosoma cruzi is still an unmet goal in several American countries. In 2007 we launched a long-term intervention program aimed to suppress house infestation with the main domestic vector in southern South America (Triatoma infestans) and domestic transmission in Pampa del Indio, a resource-constrained, hyperendemic municipality with 1446 rural houses inhabited by Creole and indigenous people, in the Argentine Chaco ecoregion. Here, we assessed whether the 10-year insecticide-based program combined with community mobilization
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Soussi, B. G., R. L. Cordtz, S. Kristensen, et al. "POS0025 INCIDENCE RATES AND POINT PREVALENCE OF SEROPOSITIVE AND SERONEGATIVE RHEUMATOID ARTHRITIS IN DENMARK: A NATIONWIDE REGISTER-BASED STUDY FROM 1998 TO 2018 USING FOUR DIFFERENT CASE CRITERIA." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 215–16. http://dx.doi.org/10.1136/annrheumdis-2021-eular.131.

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Background:Few previous studies have investigated the incidence rate (IR) and point prevalence (PP) of seropositive and seronegative rheumatoid arthritis (RA), and further, the estimates remain unknown in the Danish population.Objectives:To investigate the IR and PP of seropositive and seronegative RA in the adult Danish population from 1998 to 2018 using four register-based case definitions of RA.Methods:Nationwide register-based cohort study. Using the Danish administrative registers, patients with RA between 1998 and end of 2018 were identified. ICD-10 codes for RA were identified in the Da
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Chatzidionysiou, K., D. Di Giuseppe, J. Söderling, A. Catrina, and J. Askling. "POS0061 THE RISK OF LUNG CANCER IN RHEUMATOID ARTHRITIS AND IN RELATION TO AUTOANTIBODY POSITIVITY AND SMOKING." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 247.2–247. http://dx.doi.org/10.1136/annrheumdis-2022-eular.600.

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BackgroundLung cancer is a common malignancy in rheumatoid arthritis (RA)1,2. Since smoking is a risk factor for both (seropositive) RA and lung cancer, it remains unclear whether RA, in itself, increases lung cancer risk.ObjectivesThe aim of this study was to examine whether and to what extent the increased risk of lung cancer in RA may (or may not) be attributable to smoking, and to examine this association, both in terms of absolute and relative risks, specifically in relation to RA serostatus.MethodsWe performed a population-based cohort study of RA patients and individually matched genera
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Besombes, Camille, Richard Njouom, Juliette Paireau, et al. "The epidemiology of hepatitis delta virus infection in Cameroon." Gut 69, no. 7 (2020): 1294–300. http://dx.doi.org/10.1136/gutjnl-2019-320027.

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ObjectiveTo investigate the distribution and risk factors of hepatitis delta virus (HDV) infection in Cameroon.DesignWe tested for hepatitis B virus (HBV) surface antigen (HBsAg) and anti-HDV antibody 14 150 samples collected during a survey whose participants were representative of the Cameroonian adult population. The samples had already been tested for hepatitis C virus and HIV antibodies.ResultsOverall, 1621/14 150 (weighted prevalence=11.9%) participants were HBsAg positive, among whom 224/1621 (10.6%) were anti-HDV positive. In 2011, the estimated numbers of HBsAg positive and HDV seropo
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Ndlovu, Kwazi C. Z., and Alain Assounga. "Continuous Ambulatory Peritoneal Dialysis in Patients with HIV and End-Stage Renal Failure." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 37, no. 3 (2017): 321–30. http://dx.doi.org/10.3747/pdi.2016.00165.

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Background This study aimed to evaluate the differences in continuous ambulatory peritoneal dialysis (CAPD)-related outcomes according to human immunodeficiency virus (HIV) status of end-stage renal failure patients. Methods This prospective cohort study included 70 HIV-negative and 70 HIV-positive consecutive patients with renal failure who underwent dialysis with newly inserted Tenckhoff catheters between September 2012 and February 2015. Patients were followed up monthly at a central renal clinic for 1 year or until the primary endpoints of technique failure or death. Results Technique fail
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de Paula, Fabiana M., Bruna B. Gomes, Dirce Mary C. L. Meisel, et al. "Dynamics of anti-Strongyloides IgG antibody responses and implications for strongyloidiasis surveillance in rural Amazonians: A population-based panel data analysis." PLOS Neglected Tropical Diseases 19, no. 4 (2025): e0012967. https://doi.org/10.1371/journal.pntd.0012967.

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Background Human strongyloidiasis was recently incorporated into the World Health Organization roadmap for neglected tropical diseases targeted for control in 2021−2030. However, the prevalence, incidence, and clinical burden of Strongyloides stercoralis infection remain understudied in remote communities across the Amazon due to its chronic nature, usually with absent or unspecific clinical manifestations, and the lack of practical and sensitive diagnostics for large-scale use. Here, we apply repeated antibody testing to estimate the prevalence of anti-Strongyloides IgG responses and identify
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Magwedere, K., A. Bishi, G. Tjipura-Zaire, et al. "Brucellae through the food chain: the role of sheep, goats and springbok (Antidorcus marsupialis) as sources of human infections in Namibia." Journal of the South African Veterinary Association 82, no. 4 (2011): 205–12. https://doi.org/10.5281/zenodo.13537309.

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(Uploaded by Plazi for the Bat Literature Project) A confirmed case of human brucellosis motivated an investigation into the potential source of infection in Namibia. Since domestic animals are principal sources of Brucella infection in humans, 1692 serum samples were screened from sheep, goats and cattle from 4 presumably at-risk farms and 900 springbok (Antidorcas marsupialis) serum samples from 29 mixed farming units for Brucella antibodies by the Rose-Bengal test (RBT) and positive cases confirmed by complement fixation test (CFT). To assess the prevalence of human brucellosis, 137 abattoi
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Magwedere, K., A. Bishi, G. Tjipura-Zaire, et al. "Brucellae through the food chain: the role of sheep, goats and springbok (Antidorcus marsupialis) as sources of human infections in Namibia." Journal of the South African Veterinary Association 82, no. 4 (2011): 205–12. https://doi.org/10.5281/zenodo.13537309.

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(Uploaded by Plazi for the Bat Literature Project) A confirmed case of human brucellosis motivated an investigation into the potential source of infection in Namibia. Since domestic animals are principal sources of Brucella infection in humans, 1692 serum samples were screened from sheep, goats and cattle from 4 presumably at-risk farms and 900 springbok (Antidorcas marsupialis) serum samples from 29 mixed farming units for Brucella antibodies by the Rose-Bengal test (RBT) and positive cases confirmed by complement fixation test (CFT). To assess the prevalence of human brucellosis, 137 abattoi
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Iwamoto, Chelsea, Kelsey E. Lesteberg, Molly M. Lamb, et al. "High SARS-CoV-2 Seroprevalence and Rapid Neutralizing Antibody Decline among Agricultural Workers in Rural Guatemala, June 2020–March 2021." Vaccines 10, no. 7 (2022): 1160. http://dx.doi.org/10.3390/vaccines10071160.

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Essential agricultural workers work under occupational conditions that may increase the risk of SARS-CoV-2 exposure and transmission. Data from an agricultural worker cohort in Guatemala, and anti-SARS-CoV-2 nucleocapsid IgG (anti-N IgG) testing were used to estimate past infections and analyze risk factors associated with seropositivity at enrollment and association with SARS-CoV-2 infection. The stability of neutralizing antibody (NAb) responses were assessed in a subset of participants. The adjusted relative risk (aRR) for seroprevalence at enrollment was estimated accounting for correlatio
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KOKSAL, I., G. YILMAZ, F. AKSOY, S. ERENSOY, and H. AYDIN. "The seroprevalance of Crimean-Congo haemorrhagic fever in people living in the same environment with Crimean-Congo haemorrhagic fever patients in an endemic region in Turkey." Epidemiology and Infection 142, no. 2 (2013): 239–45. http://dx.doi.org/10.1017/s0950268813001155.

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SUMMARYCrimean-Congo haemorrhagic fever (CCHF) is endemic in Turkey, and since 2004 many cases have been reported from different regions of Turkey. There are limited data about the seroprevalence of the disease in household members of patients or persons sharing the same environment. We evaluated seroprevalence of CCHF in the immediate neighbourhood and in household members of patients living in the same environment as confirmed cases of CCHF in an endemic area of Turkey. A total of 625 healthy subjects [mean (s.d.) age: 42·3 (18·4) years, 58·7% females] without a past history of CCHF infectio
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Martinez, Rudolf Cymorr Kirby. "“Journey of Uncertainties:” Nature of Transitioning among Persons Living with Undetectable HIV." Journal of Health and Caring Sciences 2, no. 1 (2020): 19–33. http://dx.doi.org/10.37719/jhcs.2020.v2i1.oa002.

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 Introduction: The management of persons living with HIV gears towards making that person “seronegative,” undetectable in screening and practically with almost no risk of transmitting the disease. Although the trajectory of this management is clear, the process by which the person living with HIV transition from being seropositive to seronegative remains to be explored. There remains to be a paucity of research on the nature of transitioning among seronegative persons living with HIV especially from the lens of an Asian nation.
 Methodology: This study explored the nature of transit
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Mazhari, Ramin, Shazia Ruybal-Pesántez, Fiona Angrisano, et al. "SARS-CoV-2 Multi-Antigen Serology Assay." Methods and Protocols 4, no. 4 (2021): 72. http://dx.doi.org/10.3390/mps4040072.

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Serology tests are extremely useful for assessing whether a person has been infected with a pathogen. Since the onset of the COVID-19 pandemic, measurement of anti-SARS-CoV-2-specific antibodies has been considered an essential tool in identifying seropositive individuals and thereby understanding the extent of transmission in communities. The Luminex system is a bead-based technology that has the capacity to assess multiple antigens simultaneously using very low sample volumes and is ideal for high-throughput studies. We have adapted this technology to develop a COVID-19 multi-antigen serolog
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Chiang, Pai-Shan, Shin-Wei Su, Su-Lin Yang, et al. "Delayed correlation between the incidence rate of indigenous murine typhus in humans and the seropositive rate of Rickettsia typhi infection in small mammals in Taiwan from 2007–2019." PLOS Neglected Tropical Diseases 16, no. 4 (2022): e0010394. http://dx.doi.org/10.1371/journal.pntd.0010394.

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Murine typhus is a flea-borne zoonotic disease with acute febrile illness caused by Rickettsia typhi and is distributed widely throughout the world, particularly in port cities and coastal regions. We observed that murine typhus was an endemic disease (number of annual indigenous cases = 29.23±8.76) with a low incidence rate (0.13±2.03*10−4 per 100,000 person-years) in Taiwan from 2007–2019. Most (45.79%, 174/380) indigenous infections were reported in May, June, and July. The incidence rates in both May and June were statistically higher than those in other months (p<0.05). Correspondingly
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Shaffer, Brian C., Andrew Flynn, David Moorshead, et al. "Infectious Complications After Unrelated Donor Allogeneic Hematopoietic Cell Transplantation With Or Without Alemtuzumab Based In Vivo Lymphocyte Depletion." Blood 122, no. 21 (2013): 4580. http://dx.doi.org/10.1182/blood.v122.21.4580.4580.

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The addition of alemtuzumab to conditioning may decrease the incidence of graft versus host disease (GVHD) after unrelated donor (URD) allogeneic hematopoietic cell transplantation (alloHCT) but may also contribute to impaired pathogen immunity due to donor lymphocyte depletion. We identified and graded infections occurring within 6 months after URD alloHCT in 78 individuals treated either with (N=40) or without (N=38) alemtuzumab during alloHCT for hematologic cancers. Conditioning included fludarabine (120 mg/m2 total) and cyclophosphamide (4,800 mg/m2 total) over 4 days with either alemtuzu
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Kant, Surya, Ankit Kumar, Vijeta Niranjan, Darshan Kumar Bajaj, and Laxmi Devi. "Urine-lipoarabinomannan-might fill the gap in delayed diagnosis of life-threatening tuberculosis." IP Indian Journal of Immunology and Respiratory Medicine 7, no. 2 (2022): 54–59. http://dx.doi.org/10.18231/j.ijirm.2022.014.

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Mycobacterium tuberculosis bacilli is a causative organism for tuberculosis disease. The lungs are the most commonly affected organ with this infection but it can infect any vital organ of the body. The person with signs and symptoms of tuberculosis disease was identified with detection of acid-fast bacilli in the biological specimen and with rapid molecular testing. However, the limiting factor for the early tuberculosis (Tb) diagnosis is the running cost of the diagnostic test. It is the common reason preventing the advancement of diagnostic laboratories in low and middle-income countries. T
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Vuković, Igor. "Issues of criminal transmission of HIV." Crimen 1, no. 1 (2010): 66–90. https://doi.org/10.5937/crimen1001066v.

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Unlike many other countries, which apply existing criminal law offences to conduct that transmits HIV or risks transmission, Serbia enacted legislation that specifically prohibits and penalizes transmission of HIV as an offence against public health. Under Serbian law (according to Art. 250 of the Serbian Criminal Code), a person who knowingly endangers another person with infection by HIV virus may be guilty of a crime. The first issue this article addresses comes from the fact that this crime involves sexual act as an activity to which the participants are usually consenting. The author hold
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Ascione, S., C. Salliot, F. Artaud, et al. "POS1437 ASSOCIATION BETWEEN BEVERAGE CONSUMPTION AND RISK OF RHEUMATOID ARTHRITIS: A PROSPECTIVE STUDY FROM THE FRENCH E3N COHORT." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1062.1–1062. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3660.

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BackgroundThe role of nutrition in the pathogenesis of RA has been suggested in many studies but remains controversial.ObjectivesTo assess the relationship between consumption of the most frequently drinked specific beverages (coffee, tea, alcohol, and soft drinks) and the risk of RA.MethodsThe E3N Study (Étude Épidémiologique auprès des femmes de la Mutuelle Générale de l’Éducation Nationale) is a French prospective cohort including 98,995 women since 1990. RA cases have been previously identified with specific questionnaires and medication reimbursement database (1). Food and beverage consum
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Golden, Subhash Kumar Mishra, and Nidhi Vishnoi. "LONG-TERM INCIDENCE OF CERVICAL CANCER IN WOMEN WITH HUMAN IMMUNODEFICIENCY VIRUS." Journal of Drug Delivery and Therapeutics 8, no. 5-s (2018): 394–99. http://dx.doi.org/10.22270/jddt.v8i5-s.1996.

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Background: The objective of this study was to estimate the incidence of invasive cervical cancer (ICC) in women with human immunodeficiency virus (HIV) and compare it with the incidence in HIV-uninfected women.
 Methods: In a cohort study of HIV-infected and uninfected women who had Papanicolaou tests obtained every 6 months, pathology reports were retrieved for women who had biopsy results or a self report of ICC. Histology was reviewed when reports confirmed ICC. Incidence rates were calculated and compared with those in HIV-negative women.
 Results: After a median follow-up of 10
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Alzubiery, Tawfique, and Sameh Taha. "Pattern of Cytomegalovirus among Yemeni Population." Journal of Preventive Medicine,Infectious Diseases & Therapy 2, no. 1 (2025): 1–10. https://doi.org/10.63721/25jpmidt0103.

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The Cytomegalovirus is highly prevalent worldwide, the prevalence varied according to country and the epidemiological factors and ranged from 100% in both Africa and Asia to 80% in Europe and North America. CMV establishes lifelong latency that can lead to periodic reactivation spontaneously or in conditions where immunity is suppressed. In addition, CMV can be easily transmitted from person to person by direct contact, with saliva, semen, vaginal fluids, blood, urine, tears, feces, and maternally from pregnant women to infant or by breast milk feeding. CMV infections are could be a symptomati
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