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Dissertations / Theses on the topic 'Serotonin (5-HT) receptors'

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1

Quérée, Philip. "Feedback control in the central 5-HT system : evidence for a role of 5-HT₂c receptors." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670061.

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2

Liwicki, Gemma Michele. "The design and synthesis of 5-HT₁B receptor antagonists." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608202.

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3

Benjamin, Daniel E. (Daniel Ernest). "The effects of sustained gepirone administration on rodent brain 5-HT receptors and behavioral analogues of anxiety." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc798440/.

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Clinical evidence has demonstrated that the anxiolytic effects produced by the selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist, gepirone, increase progressively over one to three weeks of treatment.
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4

Cohen, Zvi. "Central serotonin (5-HT) neurons in the control of the cerebral circulation, anatomical basis and functional receptors." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0003/NQ44387.pdf.

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5

Cohen, Zvi 1967. "Central serotonin (5-HT) neurons in the control of the cerebral circulation : anatomical basis and functional receptors." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37543.

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Serotonin (5-hydroxytryptamine, 5-HT) is known to influence cerebrovascular functions such as local cerebral blood flow (CBF) and blood brain barrier (BBB) permeability, and has been implicated in cerebrovascular diseases. The present study used a multifaceted approach to determine the distribution, density and origin of the 5-HT innervation of blood vessels at the base of the brain and overlying the cerebral cortex as well as those embedded in the cortical parenchyma. In addition, the type(s) of 5-HT receptor(s) present on intracortical blood vessels as well as their precise cellular localiza
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6

Kinoshita, Minako. "Regulation of adipocyte differentiation by activation of serotonin (5-HT) receptors 5-HT2AR and 5-HT2CR and involvement of microRNA-448-mediated repression of KLF5." Kyoto University, 2010. http://hdl.handle.net/2433/131915.

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7

Zhou, Zhu. "Exploring the effects of 5-HT2A and AMPA receptors on brain 5-HT via a mechanism-based pharmacodynamic model." Scholarly Commons, 2014. https://scholarlycommons.pacific.edu/uop_etds/143.

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Depression is a common mood disorder. Although major ethical challenges make it nearly impossible to invasively and directly measure serotonin (5-hydroxytryptamine, 5-HT) levels in human brains, neuroimaging technologies have shown macroscopic structural and functional abnormalities in the prefrontal cortex (PFC) of depressed patients. The monoamine hypothesis of depression is based on the neurotransmitter imbalance, such as deceased serotonin brain levels are implicated in the cause of depression. Research has focused on the control mechanisms involved in the dorsal raphé nucleus (DRN) which
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8

Thirumaran, Sangeetha-Laura. "Polypharmacologie des récepteurs mélatoninergiques et sérotoninergiques à visée thérapeutique Structure-activity relationships of serotonin 5-HT 7 receptors ligands: A review." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMC406.

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Un des enjeux actuels de santé publique est de proposer de nouvelles stratégies pour le traitement de pathologies neurodégénératives et neuropsychiatriques qui, de part leurs origines multifactorielles, restent difficiles à traiter. Ces dernières décennies ont vu l’émergence d’une nouvelle alternative thérapeutique prometteuse, en vue d’obtenir non seulement une action préventive mais aussi curative : la polypharmacologie. Des effets neuroprotecteurs et pro-cognitifs ont ainsi été mis en évidence in vivo par la modulation simultanée de différentes cibles biologiques impliquées dans la physiopa
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9

Majeed, Zana R. "MODULATORY ACTIONS OF SEROTONERGIC SYSTEM IN CARDIAC FUNCTION, BEHAVIOR, AND SENSORIMOTOR CIRCUIT ACTIVITY IN DROSOPHILA MELANOGASTER." UKnowledge, 2016. http://uknowledge.uky.edu/biology_etds/32.

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In this dissertation, I have focused on the role of serotonin (5-HT) as a modulator in heart rate, feeding and locomotion behaviors as well as sensorimotor circuit activity in Drosophila melanogaster. A general overview in the actions of the serotonergic (5-HTergic) system on the larval heart and nervous system in larvae and adults is reviewed in Chapter One. I sought to further study the actions of serotonergic system to provide additional insights into cellular and molecular underpinnings in the actions of 5-HT.In Chapter two, I present studies on mechanisms of action by 5-HT in larvae cardi
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10

Jouha, Jabrane. "Conception, synthèse et évaluation biologique de nouveaux ligands sérotoninergiques 5-HT₇." Thesis, Orléans, 2017. http://www.theses.fr/2017ORLE2013/document.

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Dès la découverte des récepteurs 5-HT₇ en 1993, des études intenses de relation structure-activité ont été poursuivies par plusieurs groupes de recherches, dont notre laboratoire. En conséquence, un nombre impressionnant de ligands potentiels 5-HT₇ sont référencés dans la littérature mais peu sont des agonistes sélectifs. Dans ce contexte, ce travail de thèse a pour but principal, la conception de quatre classes distinctes de ligands et leur évaluation en tant que ligand agoniste des 5-HT₇R. Dans un premier temps, nous nous sommes intéressés à la préparation de ligands de type 2,4-diaminopyrid
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11

Oh, Eugene. "Postsynaptic Effectors of Neuron Morphology and Function: Part I. Characterization of Postsynaptic Drosophila Syndapin. Part II. Chimeric Light-Activated Receptors for the Control of 5-ht1a Signaling." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1291397945.

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12

Ayme-Dietrich, Estelle. "Implication de la sérotonine et des récepteurs 5-HT 2A/2B dans le remodelage des valves cardiaques et des bioprothèses valvulaires." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAJ099.

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L’hypothèse d’un lien entre valvulopathies et surexpression du système sérotoninergique fait suite aux lésions valvulaires observées lors de tumeurs carcinoïdes (taux sanguins de 5-HT élevés) et lors de l’utilisation chronique d’agonistes sérotoninergiques 5-HT2 (comme les dérivés de l’ergot de seigle, les fenfluramines). Le dogme actuel repose sur un effet prolifératif de la sérotonine, activant des cellules résidentes valvulaires, mais ne suffit pas à expliquer la dégénérescence de bioprothèses acellulaires. Nos travaux ont permis d’identifier des cellules progénitrices endothéliales (CD34+/
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13

Verdonk, Marinus Leendert. "Reflections on structural aspects of Serotonin 5-HT 2C receptor pharmacology = Beschouwingen over structurele aspecten van Serotonine 5-HT 2C receptor farmacologie /." [S.l. : s.n.], 1995. http://www.gbv.de/dms/bs/toc/227501942.pdf.

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14

Jaber, Fadi Luc. "The Physiological Role of Serotonergic Transmission in Adult Rat Taste Buds." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1357250524.

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15

Hooft, Johannes A. van. "Molecular pharmacology of the serotonin 5-HT 3 receptor : three concepts concerning a ligand-gated ion channcel = Moleculaire farmacologie van de serotonine 5-HT 3 receptor /." [S.l. : s.n.], 1997. http://www.gbv.de/dms/bs/toc/238006727.pdf.

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16

Wishart, Grant. "The design and synthesis of novel heterocycles as potential 5-HT receptor ligands." Thesis, Abertay University, 1997. https://rke.abertay.ac.uk/en/studentTheses/bfc1f404-1d94-4881-afc6-7c18bd649cdc.

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The seven transmembrane α-helices of the human 5 -HT<sub>1A</sub> , 5-HT<sub>1Dα</sub> and 5-HT<sub>1Dβ</sub> receptors have been modelled using the 3-dimensional coordinates of the seven transmembrane a-helices of the bacterial protein bacteriorhodopsin as a template. The probable 5-HT binding site was identified between helices 3, 4, 5 and 6. Interactions between the natural ligand 5-HT (A) and the receptor models are described in detail and the agonist binding site is further validated by the docking of four known 5-HT receptor ligands. The models are able to account qualitatively for the r
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17

Klenc, Jeffrey D. "Design and Synthesis of Novel Serotonin Receptor Ligands." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/chemistry_diss/50.

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Novel and potent ligands to the serotonin7 (5-HT7) receptor have been synthesized. The synthesized compounds include a set of substituted pyrimidines which show high affinity to the 5-HT7 receptor, synthesized by previously described methods [1,2] in high yield. Comparing the affinities of substituted pyrimidines to previously calculated models [3,4] yielded new hypotheses about the nature of interaction between the pyrimidine ligands and the 5-HT7 binding site. Several new series of compounds were synthesized by various methods to validate these hypotheses, including a conjugate addition t
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18

Rossi, Dania V. "Regional differences in the regulation of 5-HT₁A receptor function at the level of 5-HT₁A receptor-G protein interaction following chronic antidepressant treatment : a dissertation /." San Antonio : UTHSC, 2007. http://proquest.umi.com/pqdweb?did=1428839281&sid=1&Fmt=2&clientId=70986&RQT=309&VName=PQD.

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19

Strachan, Ryan Thomas. "P90 ribosomal S6 kinase 2 (RSK₂) directly phosphorylates the 5-HT₂A serotonin receptor thereby modulating signaling." Cleveland, Ohio : Case Western Reserve University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=case1247172805.

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20

Rahimian, Roshanak. "Possible role of PKC in regulation of neuronal serotonin uptake and 5-HT(2A) receptor." Thesis, University of Ottawa (Canada), 1995. http://hdl.handle.net/10393/10006.

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We investigated whether neuronal serotonin uptake is regulated by PKC. ($\sp3$H) 5-HT uptake and its kinetics parameters (Km and Vmax) were measured in the synaptosomal (P$\sb2$) fraction of brain tissue in vitro in the presence of different concentration of 4$\beta$-phorbol-12 myristate-13-acetate (PMA) and of a selective 5-HT uptake inhibitor, citalopram. Exposure of cortical synaptosomes to citalopram produced a marked decrease of 5-HT uptake at all time intervals of pre-incubation. However, the PKC activator PMA failed to produce unequivocal changes in the tate of 5-HT uptake by cortical
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21

RIAD, MUSTAPHA. "Les recepteurs 5-ht#1#a et 5-ht#3 de la serotonine - nouvelles approches pour l'etude de leurs implications fonctionnelles dans des cellules en culture." Paris 6, 1994. http://www.theses.fr/1994PA066686.

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Cette these est consacree a l'etude de deux recepteurs de la serotonine, un neuromediateur implique dans le controle de nombreuses fonctions du systeme nerveux central. Ces recepteurs caracterisent les deux grandes familles de recepteurs de neuromediateurs puisque le recepteur 5-ht#1#a est couple a une proteine g, tandis que le recepteur 5-ht#3 est un canal ionique. Des anticorps polyclonaux anti-recepteur 5-ht#1#a de rat ont ete produits chez le lapin en utilisant comme antigene, un peptide synthetique correspondant a un domaine tres specifique de la troisieme boucle intracytoplasmique de ce
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22

Strachan, Ryan Thomas. "P90 Ribosomal S6 Kinase 2 (RSK2) Directly Phosphorylates the 5-HT2A Serotonin Receptor thereby Modulating Signaling." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1247172805.

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23

Barclay, Elaine. "Characterisation of palmitoylation in alpha₂_A adrenoceptor and 5-HT₁_A serotonin receptor-G₀₁α G protein fusion proteins". Thesis, University of Glasgow, 2004. http://theses.gla.ac.uk/4998/.

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Palmitoylation variant GPCR-G protein fusion proteins were created between the porcine u2A-adrenoceptor or the human 5-HT1A-serotonin receptor and the pertussis toxin resistant, Cys35lIle, form of the rat Go1u protein. These palmitoylation-variant fusions were transiently expressed in HEK293T cells prior to analysis of the regulation of palmitoylation and the functional consequences of palmitoylation for both the GPCR and G protein parts of the fusions. When the regulation of palmitoylation was studied for u2A-adrenoceptor-GoluCys35IIle fusion proteins, dynamic palmitoylation and depalmitoylat
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24

Yan, Hongmei. "Stereoselective transport of drugs across the blood-brain barrier (BBB) in vivo and in vitro : pharmacokinetic and pharmacodynamic studies of the (S)- and (R)-enantiomers of different 5-HT₁A receptor agonists and antagonists /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5280-9/.

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25

Blake, Ava L. "Synthesis of Substituted Pyrimidines and Pyridines as Ligands to the 5-HT7 Receptor." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/chemistry_theses/29.

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Of the seven existing classes of serotonin receptors, the 5-HT7 receptors (5-HT7Rs) are the most recently discovered. Abundance of 5-HT7 in the central nervous system is suggestive of the receptor’s role in several physiological and pathophysiological functions. Existing research has afforded a number of compounds exhibiting specific affinity to the receptor. These selective ligands can provide structural information about the receptor and can serve as the foundation for pharmacological profiling . This thesis describes the synthesis of substituted pyrimidines and pyridines for affinity to the
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26

Sun, Jingjing. "Exploring the effect of alpha2 receptor on brain 5-HT via a mechanism-based pharmacodynamic model." Scholarly Commons, 2012. https://scholarlycommons.pacific.edu/uop_etds/154.

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Purpose: 5-hydroxytryptamine (5-HT) is an important neurotransmitter in depression. It is believed that α 1 and α 2 adrenoceptors mediate the 5-HT level in the brain. The mechanism is complex and not well explored. Especially in different combination treatments, the receptor systems may show varied modulation capability. Additionally, some research has suggested that α 2 heteroceptors may contribute to the time delay problem in dual depression treatment which is thought as the time needed for certain inhibition receptor to get desensitized. We hypothesized that the α 2 adrenoceptors had inhibi
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27

Vouret-Craviari, Valérie. "Les recepteurs mitogeniques couples aux proteines g (-thrombine et serotonine 5-ht#2) : clonage, expression fonctionnelle et mecanismes de desensibilisation." Nice, 1994. http://www.theses.fr/1994NICE4752.

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Nous nous sommes interesses a l'implication des recepteurs couples aux proteines g dans le controle de la proliferation cellulaire. Notre modele, la lignee ccl39 de fibroblastes de poumon de hamster chinois, exprime le recepteur de la serotonine de type 5-ht#2 et le recepteur de la thrombine. Ce dernier active la phospholipase c (plc) via une proteine gq et inhibe l'adenylate cyclase via une proteine gi-like sensible a la toxine pertussique. L'utilisation du recepteur 5-ht#25, qui active specifiquement la plc, nous a permis de montrer que l'activation de cette enzyme ne constitue pas un elemen
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28

KOSCIELNIAK, THIERRY. "Recepteurs de la serotonine : modelisation et etude de relations quantitatives de structure-activite de ligands des recepteurs 5-htv#1#a. syntheses, marquages et proprietes pharmacologiques de travaux ligands des recepteurs 5-ht#3." Paris 6, 1991. http://www.theses.fr/1991PA066537.

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Le travail presente dans cette these concerne l'etude des ligands des recepteurs de la serotonine (5-ht) centraux. Il comporte deux volets: 1) les recepteurs (5-ht#3 sont des canaux ioniques et les antagonistes 5-ht#3 ont des proprietes (antiemetiques, antipsychotiques. . . ) qui en font des medicaments potentiels. En prenant comme structure de base celle du zacopride, nous avons realise la synthese du premier radioligand iode des recepteurs 5-ht#3 centraux. Le #1#2#5i iodozacopride s'est avere etre un excellent outil pour l'etude autoradiographique des recepteurs 5-ht#3 dans le systeme nerveu
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29

Xie, Enzhong E. "The human serotonin 5-HT(2C) receptor: Complete cDNA, genomic structure, alternatively-spliced variant and a 200-bp exon I sequence that inhibits promoter activity /." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487942476409675.

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30

Holmberg, Pär. "Synthesis of Molecular Probes for Exploring the Human Consciousness, 5-HT7 Ligands and Salvinorins." Doctoral thesis, Uppsala University, Department of Medicinal Chemistry, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4824.

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<p>In this study, we have addressed the serotonergic and the opioid system within the CNS. Both systems are of outmost importance in the etiology of disease states, especially mental disorders. </p><p>In our investigation of the serotonergic system, we have synthesized novel enantiomerically pure 6-aryl-3-amino- and 8-aryl-3-aminochromans as ligands for the 5-HT<sub>7</sub> receptor. One reason for the lack of understanding of the physiological functionality of the serotonin 5-HT<sub>7</sub> receptor, the most recently discovered member of the serotonin receptor family, is the absence of parti
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31

Zahratka, Jeffrey Allen. "Serotonin Modulates a Calcium-Driven Negative Feedback Loop in a C. elegans Nociceptor." University of Toledo / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1449748910.

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32

Fachini, Gabriel. "O ondansetron, antagonista dos receptores 5-HT3, reverte o efeito ansiolítico das injeções de midazolam no hipocampo ventral de camundongos expostos aos modelos labirinto em cruz elevado (LCE) e exposição ao rato." Universidade Federal de São Carlos, 2012. https://repositorio.ufscar.br/handle/ufscar/1237.

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Made available in DSpace on 2016-06-02T19:22:08Z (GMT). No. of bitstreams: 1 4470.pdf: 1297687 bytes, checksum: f9b62c4b271de961a3a6053528edf8c2 (MD5) Previous issue date: 2012-02-10<br>Universidade Federal de Sao Carlos<br>Animal models have often been used to investigate the neurobiology of emotional states (fear and anxiety). In this sense, the elevated plus maze (EPM) and the rat exposure test are effective to evaluate these states and EPM exposure (aversive stimulus) can result in activation of serotonergic pathways with projections to structures belonging to the defense system, such as
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33

Castensson, Anja. "High-resolution Studies of mRNA Expression in Brain : A Search for Genes Differently Expressed in Schizophrenia." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3605.

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34

"Role of 5-HT₃ and tachykinin NK₁ receptors in drug-induced emesis and associated behaviours in the ferret and suncus murinus." 2003. http://library.cuhk.edu.hk/record=b5891693.

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Lau Hoi Yan.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2003.<br>Includes bibliographical references (leaves 134-157).<br>Abstracts in English and Chinese.<br>PUBLICATIONS BASED ON WORK IN THIS THESIS --- p.I<br>ABSTRACT --- p.II<br>ACKNOWLEDGEMENTS --- p.VI<br>TABLE OF CONTENTS --- p.VIII<br>Chapter CHAPTER 1 --- INTRODUCTION --- p.1<br>Chapter 1.1 --- General Introduction --- p.1<br>Chapter 1.2 --- Emesis --- p.3<br>Chapter 1.2.1 --- Introduction --- p.3<br>Chapter 1.2.2 --- Retching & Vomiting --- p.3<br>Chapter 1.2.3 --- Nausea --- p.4<br>Chapter 1.2.4 --- Motor Co
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35

Agahari, Fransiscus Adrian. "Serotonergic Modulation of Glutamate Release in Layer II of Rat Somatosensory Cortex: Mechanisms and Network Specificity." Phd thesis, 2017. http://hdl.handle.net/1885/133300.

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As axons from the raphe nuclei densely innervate the somatosensory cortex, the modulation of transmitter release by serotonin (5-HT) was investigated in pyramidal cells in layer II of rat barrel cortex. The idea was that 5-HT, via presynaptic 5-HT2 receptors (5-HT2R) coupled to Gq proteins, activates Ca2+ release from stores to increase spontaneous transmitter release. Addition of 10 µM 5-HT, in the presence of TTX and gabazine, caused a waxing and waning of the instantaneous mEPSC frequency. Specifically, 5-HT increased the frequency by 28 ± 7% within 5
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36

Lamarre, Amanda Kathleen. "Chronic corticosterone regulates 5-HT₁A but not 5-HT₂A agonist-induced serotonin receptor-mediated functions." Thesis, 2004. http://hdl.handle.net/2429/15636.

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There has been much research on serotonin (5-HT) 1A and 2A receptor activity, and speculation on how these receptors are implicated in the etiology of depression. Moreover, interest has been focused on mechanisms through which corticosteroids interact with these receptors to produce biochemical, physiological and behavioural changes. The 5-HT[sub 1A] and 5-HT[sub 2A] receptors appear to be controlled by corticosteroids in a biphasic manner; low corticosteroid levels exert influence on 5-HT[sub 1A] receptor activity, while high levels activate 5-HT[sub 2A] receptors. It is therefore reasonable
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Chang, Wei-Jen, and 張瑋仁. "Serotonin receptor 2B is involved in 5-HT-induced mechanical hyperalgesia." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/41415134622508026153.

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碩士<br>國立中央大學<br>生命科學研究所<br>99<br>Serotonin (5-hydroxtryptamine [5-HT]) is one of the inflammatory mediators present in central and peripheral nervous system. After injury or inflammation, 5-HT is released from platelets and mast cells to peripheral nervous system, causing pain and hyperalgesia. 5-HT receptors include seven subtypes (5HT1-7). However, it remains unclear which subtype of 5-HT receptors is involved in 5-HT-induced pain and hyperalgesia. In this study, we have investigated the roles of 5-HT2B receptors in 5-HT-induced pain and hyperalgesia. We have found that injection of 5-HT or
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38

Scott, Jacqui. "Methotrexate depletes serotonin (5-HT) production and 5-HT2B receptor expression in the small intestine of rats." Thesis, 2020. http://hdl.handle.net/2440/130838.

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39

Fentress, Hugh M. "Human 5-HT₂C̳ receptor variants functional properties and genetic associations in major depressive disorder /." Diss., 2005. http://etd.library.vanderbilt.edu/ETD-db/available/etd-06202005-085733/.

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40

Papoucheva, Ekaterina. "Die Funktionelle Rolle der Palmitilierung des 5-HT 1A Rezeptor." Doctoral thesis, 2004. http://hdl.handle.net/11858/00-1735-0000-0006-ABCA-5.

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41

Goodfellow, Nathalie M. "Serotonin 5-HT Receptor Currents in the Healthy Rodent Prefrontal Cortex and in a Model of Affective Disorders." Thesis, 2013. http://hdl.handle.net/1807/35831.

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Affective disorders represent one of the greatest global burdens of disease. Work in patients with affective disorders demonstrates that serotonin (5-HT) signaling within the prefrontal cortex, particularly at the level of the 5-HT receptors, plays an integral role in both the pathology and treatment of these diseases. Surprisingly, the characterization of the prefrontal 5-HT receptors under both healthy and pathological conditions remains incomplete. The technique of whole cell electrophysiological recording provides an unparalleled tool for investigating the functional effects of these 5-HT
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42

Kruk, Jeffrey Stephen. "Transactivation of platelet-derived growth factor receptor type ??: Mechanisms and potential relevance in neurobiology." Thesis, 2013. http://hdl.handle.net/10012/8104.

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In the absence of ligand, certain growth factor receptors can be activated via G protein-coupled receptor (GPCR) activation in a process termed transactivation. Serotonin (5-HT) receptors can transactivate the receptor tyrosine kinase (RTK) platelet-derived growth factor (PDGF) ?? receptors in smooth muscle cells, but it is not known if similar pathways occur in neuronal cells. Here, it is shown that 5-HT can transiently increase the phosphorylation of PDGF?? receptors in a time- and concentration-dependent manner in SH-SY5Y neuroblastoma cells. This transactivation pathway was pertussis-toxin
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Bokelmann, Kristin. "Charakterisierung des 5-HT3B-Promotors der Ratte vor dem Hintergrund eines mit Chemotherapie-induziertem Erbrechen assoziierten Polymorphismus." Doctoral thesis, 2011. http://hdl.handle.net/11858/00-1735-0000-0006-AE42-E.

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