Journal articles on the topic 'Serpiginous tracks'

Cutaneous larva migrans (CLM) is a zoonotic skin disorder caused by the infestation of animal hookworm larvae, the most common being Ancylostoma braziliense. The larvae penetrate the skin surface and subsequently migrate to the epidermis, leaving a typical manifestation of linear or serpiginous erythematous burrow-like tracks, known as creeping eruption. This report presented a case of a young man with complaints of the serpiginous erupted lesion over the upper left thigh, following a recent history of beach travel. On dermatological examination, an erythematous serpiginous lesion and papules were found, portraying the clinical presentation of CLM. The administration of albendazole 400 mg was started, and the symptoms were completely resolved. Keywords: larva migrans, skin disease, creeping eruption, nematodes, albendazole.

Cutaneous Larva Migrans (CLM) commonly known as creeping eruptions is a zoonotic skin infection caused by the larval stages of hookworms of dogs and cats. This disease is particularly prevalent in tropical and subtropical regions, including parts of India, where warm, humid climates and poor sanitation create ideal conditions for larval survival. Humans might contract CLM when their skin comes into contact with contaminated soil. The infection manifests as itchy, snake-like rashes on the skin, typically on the feet, hands, or other exposed areas, and can lead to discomfort and secondary bacterial infections if not managed properly. CLM is a significant public health concern, especially for vulnerable populations such as children, immunocompromised individuals, and those living in poverty-stricken areas with inadequate sanitation. Prevention is the key to control the spread of the disease, as it underscores the interconnectedness of human and animal health. Collaborative efforts between veterinarians and public health authorities are essential to implement effective prevention and control strategies. By raising awareness about CLM and promoting preventive measures, we can reduce its global burden and improve community health. This article aims to highlight the importance of understanding CLM, particularly in regions like India where it is endemic, and to emphasize the role of veterinary science in addressing zoonotic diseases.

The article presents a description of two clinical cases of “Larva migrans cutanea”. These patients had intolerable itching sensations in the skin lesions that appeared after returning from tropical countries. Clinical presentation was visualized by erythema with clear boundaries and serpiginous intradermal tracks. The diagnosis was verified on the basis of complaints, anamnesis and a characteristic clinical presentation. The treatment was included antihelmintic drug Albendazole. In both cases patients were recovered. Larva migrans cutanea with prompt and appropriate treatment lends itself well to therapy with rapid achievement of the positive effect without development of complications.

The article presents a description of two clinical cases of “Larva migrans cutanea”. These patients had intolerable itching sensations in the skin lesions that appeared after returning from tropical countries. Clinical presentation was visualized by erythema with clear boundaries and serpiginous intradermal tracks. The diagnosis was verified on the basis of complaints, anamnesis and a characteristic clinical presentation. The treatment was included antihelmintic drug Albendazole. In both cases patients were recovered. Larva migrans cutanea with prompt and appropriate treatment lends itself well to therapy with rapid achievement of the positive effect without development of complications.

<strong>RESUMEN</strong> El S&iacute;ndrome de Larva Migrans Cut&aacute;nea (LMC) es una erupci&oacute;n vesicular, ampollosa de aspecto serpiginoso, condicionada por la presencia y desplazamiento intraepid&eacute;rmico de larvas de <em>Ancylostoma</em> spp., <em>Necator americanus</em>, <em>Uncinaria stenocephala</em>, entre otros nem&aacute;todos. El objetivo fue determinar la prevalencia de LMC en pacientes atendidos en el Complejo Universitario &ldquo;Ruiz y P&aacute;ez&rdquo; y Servicio de Dermatolog&iacute;a del Hospital &ldquo;Julio Criollo Rivas&rdquo; del estado Bol&iacute;var. Se realiz&oacute; un estudio retrospectivo, revisando los archivos m&eacute;dicos durante 46 a&ntilde;os (1968-2014). Se evaluaron 100 historias m&eacute;dicas con diagn&oacute;stico confirmado de LMC. La prevalencia de LMC fue de 9 por cada 10.000 pacientes atendidos. La poblaci&oacute;n estuvo comprendida en edades entre 1 mes y 74 a&ntilde;os, con una media de 10,2 a&ntilde;os (DE &plusmn; 13,4 a&ntilde;os). El grupo etario de mayor prevalencia fue de 0 a 10 a&ntilde;os (69,0%); (<em>p</em> &lt; 0,05), en su&nbsp; mayor&iacute;a masculino (61,0%). Los meses con mayor diagn&oacute;stico de LMC fueron: septiembre (14,0%), julio y agosto (13,0%). La fuente de contagio estuvo asociada con visitas a parques (37,0%), contacto con perros (36,0%), arena (31,0%), gatos (24,0%); adicionalmente, contacto con botaderos de basura (32,0%) y ba&ntilde;os en r&iacute;os (22,0%) (<em>p</em> = 0,001). Las manifestaciones cl&iacute;nicas fueron: aumento de volumen, p&aacute;pulas eritematosas en surco serpiginosos y prurito (58,0%); predominantemente lineal (83,0%); en pie (17,0%) y mano derecha (16,0%). El tratamiento de elecci&oacute;n fue albendazol (63,0%). LMC es una entidad end&eacute;mica y durante un per&iacute;odo de 46 a&ntilde;os ha mantenido una prevalencia baja, de acuerdo a los registros de los principales centros de salud de Ciudad Bol&iacute;var, estado Bol&iacute;var. <strong>ABSTRACT</strong> Cutaneous Larva Migrans Syndrome (CML) is a vesicular, bullous eruption with a characteristic serpiginous appearance, conditioned by the presence and intraepidermal displacement of larvae of <em>Ancylostoma</em> spp, <em>Necator americanus</em>, <em>Uncinaria stenocephala</em>, among other parasitic nematodes. The purpose of the study was to determine the prevalence of CML in patients treated at the &ldquo;Ruiz y P&aacute;ez&rdquo; University Complex and Dermatology Service of the &ldquo;Julio Criollo Rivas&rdquo; Hospital in Bol&iacute;var State. A retrospective study was carried out, reviewing medical records from 46 years (1968-2014). One hundred medical records with CML confirmed diagnosis were evaluated. Prevalence of CML was 9 for every 10,000 patients attended. The age of the population in the sample was between 1 month and 74 years old, with a mean of 10.2 years (SD &plusmn; 13.4). The highest prevalence among age groups was from 0 to 10 years (69.0%) (<em>p</em> &lt; 0.05), mainly in males (61.0%). The months with the highest diagnosis were: September (14.0%), July and August (13.0%). The sources of infection were associated to visits to parks (37.0%), contact with dogs (36.0%), sand (31.0%) and cats (24.0%); in addition, contact with garbage dump (32.0%) and bathing in rivers (22.0%) (<em>p</em> = 0.001). Clinical manifestations were: increased local volume, erythematous papule in a serpiginous groove, and itching (58.0%); the shape was predominantly linear (83.0%); located on foot (17.0%) and right hand (16.0%). The preferred treatment was albendazole (63.0%). CML is an endemic entity and over a period of 46 years it has maintained a low prevalence, according to records from the main health centers in Ciudad Bol&iacute;var, Bol&iacute;var state.

Background: The skin lesions of Cutaneous Larva Migrans (CLM) commonly manifests as single, linear, irregular, serpiginous raised erythematous track, but the other clinical variants exist. This case series aimed to report one case of a vesiculobullous lesion in CLM and one case of CLM with generalized distribution serpiginous erythematous skin lesion. Objectives: We report one case of a vesiculobullous lesion in CLM and one case of CLM with generalized distribution serpiginous erythematous skin lesion. Conclusion: There were CLM with vesiculobullous lesions and also with generalized distribution of skin lesion. The pathogenesis of this condition is still unknown. In both cases, albendazole 400 mg per day for 3 and 5 days gave an effective result.

&lt;p&gt;Cutaneous larvae migrans or creeping eruption is a serpiginous cutaneous eruption caused by the accidental penetration and migration of animal hookworm (nematode) larvae through the epidermis and subcutaneous tissue. The infection occurs most frequently in warmer climates and is associated with pruritus and burning sensation&lt;span style="text-decoration: line-through;"&gt;s&lt;/span&gt;. We report a case of 48 years old farmer with vesicular lesion on left ankle progressing into a serpiginous track on the skin surface without any characteristic symptoms. Treatment with oral and topical drugs led to successful resolution of lesions within 10 days.&lt;/p&gt;

<strong>RESUMEN</strong> &nbsp; Se presenta la experiencia del diagn&oacute;stico cl&iacute;nico del s&iacute;ndrome de larva migrans cut&aacute;nea, en 11 individuos que exhibieron lesiones m&uacute;ltiples en pies, con trayectos migratorios serpiginosos, ampollas e intenso prurito nocturno. La similitud de antecedentes epidemiol&oacute;gicos y la expresi&oacute;n de las mismas manifestaciones cl&iacute;nicas en un grupo que asisti&oacute; a una reuni&oacute;n nocturna con fin recreacional, luego de haber permanecido cinco horas descalzos sobre arena de playa, cre&oacute; la sospecha del brote epid&eacute;mico. Se inspeccion&oacute; el lugar referido como posible fuente de infecci&oacute;n y adicionalmente, fueron tomadas dos muestras de arena. Se realiz&oacute; evaluaci&oacute;n microbiol&oacute;gica (por el m&eacute;todo de Baerman modificado y sedimentaci&oacute;n espontanea) y estudio granulom&eacute;trico (ASTM C136). Se demostr&oacute; la presencia de larvas rhabditiformes en transici&oacute;n (L2-L3) de <em>Ancylostoma</em> spp. Los pacientes fueron tratados con albendazol VO (400 mg cada 12 horas durante cinco d&iacute;as), observ&aacute;ndose cura cl&iacute;nica. Se recomienda evitar el contacto directo y por tiempo prolongado, en arena de playa cuando se observe fecalismo al aire libre de perros y gatos, ya que estas condiciones son un ambiente propicio para zoonosis. <strong>ABSTRACT</strong> The experience of the clinical diagnosis of cutaneous syndrome larva migrans is presented, in 11 individuals who exhibited multiple lesions on the feet, with serpeginous migratory paths, blisters and intense nocturnal itching. The similarity of epidemiological antecedents and the expression of the same clinical manifestations in a group that attended an evening meeting for recreational purposes, after having spent 5 hours barefoot on beach sand, created the suspicion of an epidemic outbreak. The place referred to as a possible source of infection was inspected and, additionally, two sand samples were taken. Microbiological evaluation (by the modified Baerman method) and granulometric study (ASTM C136) were carried out. The presence of rhabditiform larvae in transition (L2-L3) of <em>Ancylostoma</em> spp. was demonstrated. The patients were treated with albendazole PO (400 mg every 12 hours for five days), observing clinical cure. It is recommended to avoid direct contact and for prolonged time, in beach sand when fecalism is observed in the open air of dogs and cats, since these conditions are a favorable environment for zoonoses.

Hookworm-related cutaneous larva migrans is caused by the intradermal migration of soil-dwelling filariform larvae of dog and cat hookworms, most commonly Ancylostoma, usually develop itchy skin lesions, usually consisting of migrating superficial serpiginous traces, or sometimes stationary follicular eruptions. The plantar topography or on the regions of the body in contact with the sand of the beaches of the Antilles, West Africa and East Asia, the presence of fine and not very mobile serpiginous furrows and eczematization with vesiculobullous eruption, are characteristic. There are misleading profuse forms such as pseudo-folliculitis. We present a Moroccan patient who developed the disease after their return from and who responded well to treatment with albendazole.

Introduction: Cutaneous larva migrans (CLM) is a parasitic infestation that commonly occurs in warm climates among people who have contact with contaminated soil. This is caused by the migration of hookworm larvae into human skin. Clinically, itchy, erythematous, linear serpiginous tracts appear within days to months after exposure to infected sand or soil. Diagnosis is based on clinical presentation. CLM can heal on its own and usually resolves within a few weeks to several months without treatment . Case report: This case report is about a 30-year-old female patient with complaints of itching on the little finger of the left foot since 4 days ago accompanied by multiple erythematous papules with serpiginous arrangement, the surface of the left dorsal leg. Conclusion: CLM associated with hookworm is diagnosed clinically based on the typical clinical appearance, as well as a history of travel to endemic areas and exposure to contaminated soil/sand.

Graft-versus-host disease (GVHD) is an expected and relatively common complication after allogeneic hematopoietic stem cell transplantation. It may affect different organs and typically involves the skin, liver, and gastrointestinal tract (GI-GVHD). GI-GVHD may show heterogeneous presentations with peculiar diagnostic implications. Although an endoscopic biopsy is considered the “gold standard” for the diagnosis of GI-GVHD, its broad application is limited due to the poor clinical conditions usually present in these patients, including thrombocytopenia. In the emergency department, enhanced computed tomography (CECT) has emerged as the best imaging modality for the evaluation of GI damage in frail patients. However, the role of CT in the context of either acute or chronic GI-GVHD has not been systematically investigated. Herein, we focus on the radiological features found on CECT in five patients with GI-GVHD confirmed on histology. CECT was performed for the persistence of GI symptoms in three cases (case 1, case 3, and case 4), for small bowel occlusion in one case (case 5), and for acute GI symptoms in one case (case 2). Serpiginous intestinal wall appearance with multisegmental parietal thickness and homogeneous, mucosal, or stratified small bowel enhancement were common features. Colic involvement with segmental or diffuse parietal thickness was also present. One patient (case 5) presented with inflammatory jejunal multisegmental stenosis with sub-occlusion as a chronic presentation of GI-GVHD. Regarding mesenterial findings, all five patients presented comb signs in the absence of lymphadenopathy. Extraintestinal findings included biliary tract dilatation in two cases (case 2 and case 4). These data support the utility of appropriate radiological investigation in GI-GVHD, paving the way for further serial and systematic investigations to track the appearance and evolution of GI damage in GVHD patients.

Background Paravalvular or paraprosthetic leak (PVL) is a complication associated with the surgical/transcatheter implantation of a prosthetic heart valve, more commonly a mechanical than a bioprosthetic valve. Transthoracic echocardiography (TTE) is the most important diagnostic modality for prosthetic valve function/dysfunction. However, TTE often cannot differentiate the PVL from prosthetic regurgitation. Transesophageal echocardiography (TEE) is the modality of choice which is also able to detect small, nonsignificant jets. Case Report We present a case of 78-year-old male who had undergone mitral valve replacement with Epic St. Jude tissue valve 3 years back and now presented to our hospital with NYHA class III dyspnea since few months prior to admission. It was associated with cough with mucoid expectoration along with orthopnea. TTE revealed moderate PAH with increased gradient across bioprosthetic mitral valve with suspicion of peravalvular leak (Fig. 1). Three-dimensional (3D) volume rendering image analysis after cropping suggested oval perivalvular area of leakage which was confirmed with the help of 3D color rendering (Fig. 2). It showed early separation of perivalvular leak from paravalvular area. Discussion The majority of PVL are crescent, oval or roundish-shaped and their track can be parallel, perpendicular or serpiginous. Incidence of PVL, including small nonsignificant jets, is estimated to be as high as 20%.1 TEE is more useful than TTE in evaluating the shape of paravalvular defect. It may also help in assessing eccentric jets and differentiating between single and multiple jets. Major progress in TEE in the area of PVL imaging has been 3D reconstruction.2 A semiquantitative assessment of the size of PVL may be made by measurement of the ratio of total sewing ring circumference to the length of suture dehiscence (&gt;10%: Mild, 10-20%: Moderate, &gt;20%: Severe, &gt;40%: Instability of the prosthetic valve).3 Conclusion The TEE, especially if 3D volume rendering is used along with, provides a systematic method to accurately localize native and prosthetic mitral valve regurgitant lesions. Also, paravalvular leaks may be more easily delineated and quantified using 3D echo. Due to accurate localization of the defects, this modality helps to improve the preoperative assessment and decisions about patients with significant mitral regurgitation.

Cutaneous larva migrans (CLM) is a skin disorder in the form of serpiginous spreading with erythematous and papule as a skin reaction to the invasion of hookworm. Apart from the skin infection symptoms, helminthic infections tend to most frequently involve the respiratory, gastrointestinal, neurological, and eye. We report the case of a 21-year-old male who came with erythematous papules and linear tracks in the entire body that felt itchy, especially on the abdomen and at the back. On the physical examination, there were erythematous papules, erythematous tracks in serpiginous patterns, excoriations, and erosions. The patient was diagnosed with extensive CLM. The patient was treated with oral Albendazole 400 mg once daily for 3 days, oral Cetirizine 10 mg once daily to reduce the itch, and oral Cefixime 200 mg twice daily for 3 days. At the end of the follow-up, all the lesions had resolved, and no other symptoms appeared. Extensive cases of CLM are noteworthy for the presence of Loeffler syndrome and superinfection. In remote areas, sometimes, the availability of drugs is limited. Therapy using oral Mebendazole only gives 70% resolution of the skin lesion compared to Albendazole. Combination therapy of Albendazole, antihistamines, and antibiotics gave satisfactory results.

Cutaneous larvae migrans or creeping eruption is a serpiginous cutaneous eruption caused by the accidental penetration and migration of animal hookworm (nematode) larvae through the epidermis and subcutaneous tissue. The infection occurs most frequently in warmer climates and is associated with pruritus and burning sensations. We report a case of 8 years female child with vesicular lesion on left ankle progressing into a serpiginous track on the skin surface associated with itching. Treatment with albendazole led to successful resolution of lesions within 10 days.

Abstract Cutaneous larva migrans (CLM), results from hookworm larvae infestation, mainly A. braziliense or A. caninum. It is common in Sub-Saharan Africa, often acquired through soil contact, especially in sandy beaches, manifesting as serpiginous, erythematous, and intensely pruritic tracts within the epidermis and presenting with diverse clinical appearances. Diagnosis is mostly clinical, however, dermoscopy can enhance diagnostic accuracy and distinction from mimics. The current body of literature is deficient in its representation of dermoscopic data for CLM in blacks. This study explores dermoscopy in 9 dark-skinned patients with 16 CLM lesions. Distinctive serpiginous structureless areas displaying a range of colors, peripheral scales surrounding brown areas and brown dots were predominant features, whereas vascular characteristics were less evident. This article highlights the presence of distinct reaction patterns, including brown dots, scales, and accentuated, often disrupted brown reticular lines in addition to the characteristic winding tracts in the darker skin.