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Journal articles on the topic 'Sertaconazole'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

&NA;. "Sertaconazole." Reactions Weekly &NA;, no. 563 (1995): 9. http://dx.doi.org/10.2165/00128415-199505630-00028.

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Croxtall, Jamie D., and Greg L. Plosker. "Sertaconazole." Drugs 69, no. 3 (2009): 339–59. http://dx.doi.org/10.2165/00003495-200969030-00009.

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&NA;. "???and sertaconazole." Inpharma Weekly &NA;, no. 866 (1992): 23. http://dx.doi.org/10.2165/00128413-199208660-00054.

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Carrillo-Muñoz, Alfonso J., Cristina Tur-Tur, Delia C. Cárdenes, Dolors Estivill, and Gustavo Giusiano. "Sertaconazole Nitrate Shows Fungicidal and Fungistatic Activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, Causative Agents of Tinea Pedis." Antimicrobial Agents and Chemotherapy 55, no. 9 (2011): 4420–21. http://dx.doi.org/10.1128/aac.00219-11.

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ABSTRACTThe fungistatic and fungicidal activities of sertaconazole against dermatophytes were evaluated by testing 150 clinical isolates of causative agents of tinea pedis,Trichophyton rubrum,Trichophyton mentagrophytes, andEpidermophyton floccosum. The overall geometric means for fungistatic and fungicidal activities of sertaconazole against these isolates were 0.26 and 2.26 μg/ml, respectively, although values were higher forT. mentagrophytesthan for the others. This is the first comprehensive demonstration of the fungicidal activity of sertaconazole against dermatophytes.

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Raghavendra Babu, N. "MICROBIOLOGICAL ANALYTICAL METHOD FOR DETERMINATION OF SERTACONAZOLE NITRATE IN PHARMACEUTICAL FORMULATIONS." YMER Digital 21, no. 07 (2022): 1104–15. http://dx.doi.org/10.37896/ymer21.07/91.

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Sertaconazole nitrate is a third generation synthetic broad-spectrum, benzothiophene imidazole antifungal agent. A new microbiological method was developed for analysis of sertaconazole tablets using candida Albicans as test microorganism. The diffusion assay method was optimized by using different media, organisms and conditions. Prospective validation of the method showed adequate linearity (r = 0.9964), precision (% RSD<2%) and accuracy (mean recovery = 98.26%). Highperformance liquid chromatography was chosen as a comparison method for voriconazole determination. Results of both the mic

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KHAMAGANOVA, I. V., and D. F. KASHEVAROV. "APPLICATION OF SERTACONAZOLE FOR SUPERFICIAL MYCOSES COMPLICATED BY BACTERIAL INFECTION." Russian Journal of Allergy 11, no. 3 (2014): 68–72. http://dx.doi.org/10.36691/rja532.

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Sertaconazole properties are discussed in the article. According to literature data application of the derivation of benzotiafene and imidazole solves a problem of resistance towards antimycotics. Sertaconazole has a wide spectrum of activity towards fungi & bacteria and also has antiinflammatory effect. The present examination of therapeutic efficacy included 33 patients who suffered from superficial mycoses complicated by bacterial infection. Levocetirizine was prescribed in case of dermatomikides. Both monotherapy by sertaconazole and combination with levocetirizine were high effective

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Georgescu, Simona Roxana, Cristina Iulia Mitran, Madalina Irina Mitran, Andreea Amuzescu, Clara Matei, and Mircea Tampa. "A Meta-Analysis on the Effectiveness of Sertaconazole 2% Cream Compared with Other Topical Therapies for Seborrheic Dermatitis." Journal of Personalized Medicine 12, no. 9 (2022): 1540. http://dx.doi.org/10.3390/jpm12091540.

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Seborrheic dermatitis (SD) is a relapsing inflammatory skin disorder that affects the seborrheic areas of the body. Its etiology is not completely elucidated; however, the link between disease exacerbations and the proliferation of Malassezia spp., along with the good response to antifungal agents, indicate the role of fungi in its pathophysiology. Sertaconazole nitrate is a relatively new imidazole antifungal agent with a particular structure, consisting in a benzothiophene ring similar to the indole ring of tryptophan, and it acts mainly through the inhibition of ergosterol synthesis and the

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Roongpisuthipong, Anuvat, Amphan Chalermchockcharoenkit, Korakot Sirimai, et al. "Safety and efficacy of a new imidazole fungicide, Sertaconazole, in the treatment of fungal vulvo-vaginitis: a comparative study using Fluconazole and Clotrimazole." Asian Biomedicine 4, no. 3 (2010): 443–48. http://dx.doi.org/10.2478/abm-2010-0054.

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Abstract Background: Sertaconazole is a new imidazole fungicide introduced for vulvo-vaginal candidiasis. It has an azole group with benzothiophene that inhibits biosynthesis of ergosterol and brings about a massive leak of cytoplasm with consequent fungal cell death. Objective: Assess the safety and efficacy of Sertaconazole in the treatment of fungal vulvo-vaginitis for comparison with Fluconazole and Clotrimazole. Subjects and methods: One-hundred eighty-eight outpatients with fungal vulvo-vaginitis were recruited at Siriraj Hospital, Thailand between August 31, 2004 and January 30, 2006. T

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Mohit, Khandelwal, and Gupta Abhay. "Development and Evaluation Hydrogel of Sertaconazole." International Journal of Current Pharmaceutical Review and Research 15, no. 10 (2023): 319–24. https://doi.org/10.5281/zenodo.11630822.

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AbstractThe main aim of this study was to develop a topical drug delivery (Hydrogel) of Sertaconazole to reduce thedose of the active drug, to improve patient compliance, to avoid the side effects and increase local onsetabsorption and action. Sertaconazole interfare with 14-α sterol demethylase, a cytochrome P-450 enzymeessential for conversion of lanosterol to ergosterol. These turn in inhibition in synthesis of ergosterol and alsoenhance cellular permeability of fungus due to reduced amounts of ergosterol present in the fungal cellmembrane.Methods: Topical Hydrogel formulations develo

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Khondker, Lubna. "Role of Sertaconazole in the Treatment of Dermatophytosis." Medicine Today 36, no. 1 (2024): 62–66. http://dx.doi.org/10.3329/medtoday.v36i1.72905.

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Dermatophytosis is a major health burden worldwide and is now increasing day by day. Dermatophytosis is also becoming increasingly unresponsive to topical conventional antifungals now a day. Newer topical antifungals may be more effective in these patients. Sertaconazole is a new, broad spectrum, fungicidal and fungistatic imidazole with added antipruritic and anti-inflammatory activity that may be effective and beneficial in improving the quality of life for the patient with dermatophytoses. It is indicated in the European Union(EU) for the treatment of superficial skin mycoses such as dermat

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11

Saurabh, Krishna Misra, K. Singh Hariom, Ranjan Singh Ravi, and Dokania Richa. "Comparative Study of the Efficacy and Safety of Topical Antifungal Agents Clotrimazole versus Sertaconazole in the Treatment of Tinea Corporis/Cruris." International Journal of Pharmaceutical and Clinical Research 16, no. 6 (2024): 2294–97. https://doi.org/10.5281/zenodo.13140376.

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<strong>Background: </strong>Tinea corporis and tinea cruris are common dermatophytic infections affecting the skin, causing significant discomfort and morbidity. Topical antifungal agents like clotrimazole and sertaconazole are widely used for treatment. This study aims to compare the efficacy and safety of clotrimazole versus sertaconazole in the treatment of tinea corporis and tinea cruris. <strong>Materials and Methods: </strong>A total of 250 patients diagnosed with tinea corporis or tinea cruris were enrolled in this study conducted in Kaushambi, Uttar Pradesh, from July 2

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Susilo, Rudy, Hans C. Korting, Wolfgang Greb, and Uwe Phillip Strauss. "Nail Penetration of Sertaconazole with a Sertaconazole-Containing Nail Patch Formulation." American Journal of Clinical Dermatology 7, no. 4 (2006): 259–62. http://dx.doi.org/10.2165/00128071-200607040-00007.

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Nakka, Annie Ratnam, Janardhan Bommakanti, Siva Rami R. Karumuri, and Naresh B. Thambisetti. "Evaluation of newer imidazoles in dermatophytosis." International Journal of Research in Dermatology 6, no. 1 (2019): 75. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20195677.

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<p class="abstract"><strong>Background:</strong> Eberconazole, a newer Imidazole derivative, antimycotic drug. Similarly, sertaconazole and luliconazole are also newer antifungal which all exhibit fungicidal, fungistatic and anti-inflammatory actions. But, sertaconazole in addition have antipruritic effect also.</p><p class="abstract"><strong>Methods:</strong> Randomized, open-labelled, prospective study comprising of 75 patients divided into three equal groups A, B, C of 25 patients each. Group A received eberconazole 1%, Group B received sertaconazol

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Gasparyan, S. A., A. A. Khazhbiev, and V. V. Ryzhkov. "Experience with sertaconazole in pregnant women with vulvo-vaginal candidiasis." Medical Council, no. 13 (October 10, 2019): 160–65. http://dx.doi.org/10.21518/2079-701x-2019-13-160-165.

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Objective. To evaluate the clinical efficacy of sertaconazole in the treatment of acute vulvo-vaginal candidiasis (VVC) in pregnant women with caesarean section. Subject and methods. The study included 136 pregnant women. In the treatment, 1 candle of sertaconazole 300 mg once was used. Efficacy was evaluated after 7 and 28 days. Results. At 74.0% of pregnant women identified VVK. After treatment with sertaconazole, positive dynamics was observed in 91.9% of patients, in whom clinical manifestations of the disease disappeared by the third day. Culture testing revealed a normalization of the va

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Lakhani, Som J., Dhaval B. Joshi, Kalindi R. Kumbhani, and Rajesh B. Haldia. "Prospective study on comparison of efficacy of topical anti-fungal agents: clotrimazole 1% and sertaconazole 2% in treatment of tinea cruris." International Journal of Research in Dermatology 6, no. 1 (2019): 43. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20195672.

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<p class="abstract"><strong>Background:</strong> Tinea cruris is a common superficial dermatophytic infection of the skin occurring in 20-25% population worldwide. The various types of antifungal agents are available for topical use in treatment of tinea cruris. Clotrimazole is conventional imidazole antifungal drug whereas sertaconazole is newer imidazole antifungal claimed to be superior to clotrimazole in tinea infection. The aim of the study was to determine and compare the efficacy of potent topical azole agents 1% clotrimazole and 2% sertaconazole in patients diagnosed

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Pajić, Nataša Z. Bubić, Marija N. Todosijević, Gordana M. Vuleta, et al. "Alkyl polyglucoside vs. ethoxylated surfactant-based microemulsions as vehicles for two poorly water-soluble drugs: physicochemical characterization and in vivo skin performance." Acta Pharmaceutica 67, no. 4 (2017): 415–39. http://dx.doi.org/10.1515/acph-2017-0036.

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Abstract Two types of biocompatible surfactants were evaluated for their capability to formulate skin-friendly/non-irritant microemulsions as vehicles for two poorly water-soluble model drugs differing in properties and concentrations: alkyl polyglucosides (decyl glucoside and caprylyl/capryl glucoside) and ethoxylated surfactants (glycereth-7-caprylate/ caprate and polysorbate 80). Phase behavior, structural inversion and microemulsion solubilization potential for sertaconazole nitrate and adapalene were found to be highly dependent on the surfactants structure and HLB value. Performed charac

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&NA;. "Glenmark launches sertaconazole in India." Inpharma Weekly &NA;, no. 1637 (2008): 22. http://dx.doi.org/10.2165/00128413-200816370-00069.

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Romero, A., M. T. Grau, F. Villamayor, et al. "Ocular tolerance of sertaconazole gel." Mycoses 39, no. 1-2 (1996): 57–60. http://dx.doi.org/10.1111/j.1439-0507.1996.tb00085.x.

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&NA;. "Sertaconazole effective for tinea pedis." Inpharma Weekly &NA;, no. 1566 (2006): 11. http://dx.doi.org/10.2165/00128413-200615660-00024.

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Kutueva, Flora R., Ruslan I. Glushakov, Natalia I. Tapilskaya, Alla E. Nikolaeva, Artem A. Poromov, and Olga A. Pustotina. "Flucovag: efficacy and safety in patients with vulvovaginal candidiasis: a prospective, multicenter, open-label, randomized, comparative clinical study." Gynecology 25, no. 1 (2023): 55–61. http://dx.doi.org/10.26442/20795696.2023.1.202037.

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Design. A prospective, multicenter, open-label, randomized, comparative clinical study. Objective. To compare the efficacy and safety of Flucovag (sertaconazole) vaginal suppositories, 300 mg (OTCPharm JSC, Russia; manufactured by Altpharm LLC, Russia) and the brand-name drug Zalain (sertaconazole), 300 mg (Egis Pharmaceuticals PLC, Hungary) in the treatment of vulvovaginal candidiasis. Materials and methods. The study included female patients (1855 years old) with uncomplicated vulvovaginal candidiasis treated in outpatient settings. In total, 220 patients were randomized into two

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Castelló, J. M. "Sertaconazole Nitrate < Rec INNM >." Drugs of the Future 16, no. 3 (1991): 213. http://dx.doi.org/10.1358/dof.1991.016.03.132977.

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Elisyutina, O. G., E. S. Fedenko, and O. V. Shtirbul. "Sertaconazole in treatment of atopic dermatitis patients." Russian Journal of Allergy 10, no. 2 (2013): 66–73. http://dx.doi.org/10.36691/rja647.

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Kruglova, L. S., and N. O. Pereverzina. "Efficacy of topical forms of sertaconazole in treatment of mycoses of skin." Medical alphabet, no. 24 (November 8, 2023): 41–46. http://dx.doi.org/10.33667/2078-5631-2023-24-41-46.

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Published research results indicate the high effectiveness of sertaconazole in the treatment of mycoses of the skin. According to a number of studies, it is superior to other antifungal agents in terms of cure rate and speed of action, and also has anti-inflammatory and antipruritic activity.Material and methods. The aim of the observational study was to evaluate the effectiveness of Zalain cream (sertaconazole 2%) in patients with mycosis of the smooth skin of the groin area. We observed 21 patients (13 men and 8 women) aged from 37 to 72 years with a verified diagnosis of mycosis of smooth s

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Sharmeen, Ayesha, Syed Suhail Amin, Mohammad Adil, and Iti Varshney. "Study of effect of oral itraconazole with 2% sertaconazole cream versus oral terbinafine with 2% sertaconazole cream in dermatophytosis." International Journal of Research in Dermatology 9, no. 5 (2023): 274–81. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20232542.

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Background: Dermatophytosis is a common dermatological problem. Recent studies have reported an increase in the prevalence of the disease. Management of dermatophytosis thus has become challenging for both dermatologists and patients due to their resistance to treatment and their refractory nature. Currently the management of dermatophytic infection includes both oral and topical antifungals. The study compared the clinical efficacy and adverse effect profile of systemic with topical drugs. Methods: Patients were randomly divided into two groups of 90 each. They were given oral Itraconazole 10

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Kothari, R., R. Sadoughifar, Torello Lotti, and Mohamad Goldust. "Efficacy of 1% clotrimazole cream versus 2% sertaconazole cream in the management of seborrheic dermatitis: A randomized controlled trial." Russian Journal of Skin and Venereal Diseases 23, no. 3 (2020): 146–49. http://dx.doi.org/10.17816/dv48905.

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Background: Antifungals are regarded as one of the first line agents in the management of seborrheic dermatitis (SD). However, the data on head to head comparison among various antifungal agents is deplete and is required to broaden the number of first line agents that can be used in SD treatment. Aim: To compare the efficacy of 1% clotrimazole cream with 2% sertaconazole cream in the management of SD. Methods: 60 patients of SD were included and divided into 2 groups. The first group (n = 30) received topical 2% sertoconazole cream for twice a day application for four weeks. The o

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Borovikov, I. O., I. I. Kutsenko, O. I. Borovikova, et al. "Possibilities of local therapy of recurrent candidiasis against the background of mixed vaginal dysbiosis." Meditsinskiy sovet = Medical Council, no. 15 (October 21, 2023): 83–93. http://dx.doi.org/10.21518/ms2023-295.

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Introduction. The article describes the experience of treating patients with recurrent vulvovaginal candidosis combined with mixed vaginal dysbiosis using a variant of complex local therapy with drugs containing sertaconazole nitrate and benzyl-dimethyl-[3-(myristoylamino) propyl] ammonium chloride monohydrate.Aim. To evaluate the efficacy of local therapy in patients with recurrent vulvovaginal candidosis with underlying mixed non-specific vaginal dysbiosis.Materials and methods. A prospective open randomized clinical trial to evaluate the outcomes of treatment with drugs containing sertacona

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Efendieva, Z. N. "Sertaconazole in the treatment of vulvovaginal candidiasis." Medical Council, no. 13 (October 10, 2019): 94–98. http://dx.doi.org/10.21518/2079-701x-2019-13-94-98.

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Vulvovaginal candidiasis today is one of the most pressing problems in the field of women’s health. However, the prevalence of Candida with formed drug resistance to fluconazole significantly complicates the treatment of this disease. Thus, the evaluation of the safety and efficacy of other antimycotic drugs becomes an important task in the fight against recurrent genital candidiasis. The article presents the data of international and domestic studies on the possibilities of using sertaconazole in the therapy of vulvovaginal candidiasis.

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&NA;. "Sertaconazole preferred over miconazole in cutaneous mycoses." Inpharma Weekly &NA;, no. 841 (1992): 18. http://dx.doi.org/10.2165/00128413-199208410-00029.

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Palacı́n, C., C. Tarragó, and J. A. Ortiz. "Sertaconazole: pharmacology of a gynecological antifungal agent." International Journal of Gynecology & Obstetrics 71 (December 2000): 37–46. http://dx.doi.org/10.1016/s0020-7292(00)00351-9.

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Eldemiri, Omar Magdy, Germeen NS Girgis, Sara Hamdy Fouad, and Thanaa Mohamed Borg. "Improved Topical Antifungal Medication using Sertaconazole Bilosomes: In vitro Permeability, Cytotoxicity, and Clinical Assessment." Journal of Pharmaceutical Research International 36, no. 7 (2024): 96–117. http://dx.doi.org/10.9734/jpri/2024/v36i77541.

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Objective: The purpose of the current study was to develop Sertaconazole bilosomes (SBs) with enhanced permeability, skin deposition, anti-fungal properties, and clinical efficacy. Methods: By changing span 60 to cholesterol molar ratio, bile salt type, and concentration, 12 formulations of SBs were prepared using the thin film hydration method and characterized by particle size (PS), zeta potential (ZP), polydispersity index (PDI), % entrapment efficiency (% EE), and % cumulative drug released after 8h (% Q8h ) and 24h (% Q24h). The optimized formulation (SB 5) was incorporated into 1% Carbop

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Carrillo-Muñoz, Alfonso J., Gustavo Giusiano, Pilar Ariadna Ezkurra, and Guillermo Quindós. "Sertaconazole: updated review of a topical antifungal agent." Expert Review of Anti-infective Therapy 3, no. 3 (2005): 333–42. http://dx.doi.org/10.1586/14787210.3.3.333.

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Lopez-Montero, Elena, Jose-Fernando Rosa dos Santos, Juan J. Torres-Labandeira, Angel Concheiro, and Carmen Alvarez-Lorenzo. "Sertaconazole-Loaded Cyclodextrin - Polysaccharide Hydrogels as Antifungal Devices§." Open Drug Delivery Journal 3, no. 1 (2009): 1–9. http://dx.doi.org/10.2174/1874126600903010001.

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Chetan, Sharma, Agrawal Dilip, Khandelwa Mohit, and Mahatma Gandhi College of Pharmaceutical Sciences Jaipur Rajasthan Professor. "DESIGN, DEVELOPMENT AND EVALUATION ANTIFUNGAL OLEOGEL OF SERTACONAZOLE." International Journal of Current Pharmaceutical Review and Research 14, no. 03 (2022): 113–17. https://doi.org/10.5281/zenodo.12658837.

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The main purpose of the study is to develop a topical drug delivery (Oleogel) system ofSerteconazole to reduce side effect the dose of the active drug, to improve patientcompliance, and increase local onset absorption and action. Sartaconazole interacts with 14-αdemethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. Asergosterol is an essential component of the fungal cell membrane, inhibition of its synthesisresults in increased cellular permeability causing leakage of cellular contents. TopicalOleogel formulations development of Serteconazole was prepared

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J., Sumyuktha, Murali Narasimhan, and Parveen Basher Ahamed. "A comparative trial between the therapeutic efficacy of topical 2% sertaconazole cream and 1% terbinafine cream in the treatment of tinea cruris/tinea corporis." International Journal of Research in Dermatology 3, no. 1 (2017): 59. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20170082.

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<p class="abstract"><strong>Background:</strong> Skin infections caused by dermatophyte fungi account for 6% of dermatology consultations at our hospital and 3 to 4% worldwide. A variety of antifungal agents are available for topical use. Terbinafine 1% cream is considered the first line topical medication in the treatment of dermatophytosis. Sertaconazole 2% cream is a relatively new drug having antifungal as well as antiflammatory property. In this prospective study we sought to compare the safety and efficacy of topical 2% Sertaconazole and 1% Terbinafine creams in the tre

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Е., Н. Носенко, and П. Головатюк Е. "Modern methods of diagnosis and treatment of vaginal dysbiosis caused by mushrooms of the genus Candida." REPRODUCTIVE ENDOCRINOLOGY, no. 36 (September 14, 2017): 64–72. https://doi.org/10.18370/2309-4117.2017.36.64-72.

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The article presents literature data on modern approaches to diagnosis and treatment of vaginal dysbiosis caused by fungi of the genus Candida and personal data on the effectiveness of vaginal dysbiosis treatment in women with recurrent miscarriage occurring in ART cycles by combined local therapy with sertaconazole and povidone-iodine. 240 patients of reproductive age with habitual miscarriage of pregnancy after ART and 30 conditionally healthy fertile women were examined. The state of vaginal microbiota was studied using PCR and culture. It were carried out a species identification of the fu

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Venkateswarlu Rayudu, S., and P. Kumar. "An Easy, Efficient and Improved Synthesis of Sertaconazole Nitrate." Russian Journal of Organic Chemistry 55, no. 8 (2019): 1212–16. http://dx.doi.org/10.1134/s1070428019080219.

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Wang, Peng-Hui, Hsiang-Tai Chao, Cheng-Li Chen, and Chiou-Chung Yuan. "Single-dose Sertaconazole Vaginal Tablet Treatment of Vulvovaginal Candidiasis." Journal of the Chinese Medical Association 69, no. 6 (2006): 259–63. http://dx.doi.org/10.1016/s1726-4901(09)70253-9.

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Liebel, Frank, Peter Lyte, Michelle Garay, Jeffrey Babad, and Michael D. Southall. "Anti-inflammatory and anti-itch activity of sertaconazole nitrate." Archives of Dermatological Research 298, no. 4 (2006): 191–99. http://dx.doi.org/10.1007/s00403-006-0679-8.

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Guarro, J., M. J. Figueras, and J. Cano. "Alterations Produced by Sertaconazole on the Morphology and Ultrastructure of Candida albicans: Sertaconazol-bedingte Veranderungen der Morphologie und Ultrastruktur von Candida albicans." Mycoses 32, no. 6 (2009): 283–95. http://dx.doi.org/10.1111/j.1439-0507.1989.tb02246.x.

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Prithpal, S. Matreja. "Comparison of safety and efficacy of Oral Terbinafine with Amphotericin B gel and Sertaconazole cream for the treatment of Tinea Corporis and its effect on quality of life of patients." International Journal of Dermatology and Clinical Research 3, no. 1 (2017): 018–21. https://doi.org/10.17352/2455-8605.000021.

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<strong>Background:</strong> Tinea Corporis is a superfi cial fungal infection affecting 20-25% of the world’s population. Management involves using topical and oral antifungal drugs. Terbinafi ne has been used commonly for the treatment of tinea corporis to prevent the emergence of resistance combination of drugs is used. Hence, this study was designed to compare the safety and effi cacy of Sertaconazole and Amphotericin B when either is used with oral Terbinafi ne.

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Kruglova, L. S., and R. Yu Mayorov. "Mycoses of the skin: Issues of effective therapy." Medical alphabet 1, no. 27 (2022): 24–28. http://dx.doi.org/10.33667/2078-5631-2022-27-24-28.

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A practicing physician always faces a rather difficult task when choosing a topical drug for the treatment of mycoses, while the optimal ratio of efficacy/safety and a wide spectrum of action, including against possible contamination by various pathogens, can be considered a priority factor. Sertaconazole (Zalain) is a highly active broad-spectrum antifungal drug that has fungicidal, antibacterial, anti-inflammatory and antipruritic effects.Material and methods. On an outpatient basis, under our supervision were 25 patients aged 42 to 76 years with a verified diagnosis of foot mycosis, confirm

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Carrillo-Muñoz, A. J., B. Fernandez-Torres, and J. Guarro. "In VitroAntifungal Activity of Sertaconazole Against 309 Dermatophyte Clinical Isolates." Journal of Chemotherapy 15, no. 6 (2003): 555–57. http://dx.doi.org/10.1179/joc.2003.15.6.555.

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Figueras, M. J., J. F. Cano, and J. Guarro. "Ultrastructural alterations produced by sertaconazole on several opportunistic pathogenic fungi." Medical Mycology 33, no. 6 (1995): 395–401. http://dx.doi.org/10.1080/02681219580000761.

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Nemutlu, Emirhan, Ceren Yardımcı, and Nuran Özaltın. "Determination of sertaconazole in pharmaceutical preparations by capillary zone electrophoresis." Analytica Chimica Acta 547, no. 1 (2005): 83–88. http://dx.doi.org/10.1016/j.aca.2004.09.059.

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Torres, J., M. Márquez, and F. Camps. "Sertaconazole in the treatment of mycoses: from dermatology to gynecology." International Journal of Gynecology & Obstetrics 71 (December 2000): 3–20. http://dx.doi.org/10.1016/s0020-7292(00)00349-0.

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Sahoo, Susijit, Nihar Ranjan Pani, and Sunit Kumar Sahoo. "Microemulsion based topical hydrogel of sertaconazole: Formulation, characterization and evaluation." Colloids and Surfaces B: Biointerfaces 120 (August 2014): 193–99. http://dx.doi.org/10.1016/j.colsurfb.2014.05.022.

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Moura, Sofia, Paulo Duarte, Ana Sofia Oliveira, José Martinez-de-Oliveira, Ana Palmeira-de-Oliveira, and Joana Rolo. "Azole Antifungal Consumption in Community Pharmacy Sales in Mainland Portugal: Trend Analysis from 2014 to 2023." Antibiotics 14, no. 1 (2025): 33. https://doi.org/10.3390/antibiotics14010033.

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Background/Objectives: Excessive or inadequate use of antimicrobial drugs may lead to the emergence of resistant strains. For this reason, it is important to monitor consumption indicators to assess drugs’ utilization over time. This study aimed to analyze the consumption of medically prescribed azole antifungal drugs in mainland Portugal from 2014 to 2023, focusing on those directed to genital infections: fluconazole, isoconazole, itraconazole, and sertaconazole. Methods: For each drug, the evaluated parameters were the total number of packages, number of packages per 1000 inhabitants, define

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Mohammed, Rasheeduddin. "Cutaneous phaeohyphomycosis of foot web by Curvularia lunata." Global Journal of Medical and Clinical Case Reports 4, no. 3 (2017): 074–75. https://doi.org/10.17352/2455-5282.000053.

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A case of cutaneous phaeohyphomycosis of the foot affecting interdigital spaces between toes in a 31 year old immunocompetent male with no history of diabetes is illustrated. Fugal elements were found in direct microscopic examination of skin scrapping. The etiologic agent was identified as Curvularia lunata based on macromophology and microscopic examination of pure culture growth. The patient was prescribed with a topical cream containing sertaconazole nitrate and oral itraconazole by the treating dermatologist. Nondermatophyte infections clinically mimic dermatophytosis, and microscopically

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Harsha, G., Naseeb Basha Shaik, PK Lakshmi, and K. Latha. "Formulation and evaluation of sertaconazole nitrate loaded nanosponges for topical application." RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY 14, no. 2 (2021): 895–902. http://dx.doi.org/10.5958/0974-360x.2021.00159.1.

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Abdellatif, Menna M., Islam A. Khalil, Yara E. Elakkad, Hesham A. Eliwa, Tamer Samir, and Asmaa K. Al-Mokaddem. "Formulation and Characterization of Sertaconazole Nitrate Mucoadhesive Liposomes for Vaginal Candidiasis." International Journal of Nanomedicine Volume 15 (June 2020): 4079–90. http://dx.doi.org/10.2147/ijn.s250960.

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