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Relevant bibliographies by topics / Sertoli cells

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Academic literature on the topic 'Sertoli cells'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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Journal articles on the topic "Sertoli cells"

1

Xiong, Weipeng, Haikun Wang, Hui Wu, Yongmei Chen, and Daishu Han. "Apoptotic spermatogenic cells can be energy sources for Sertoli cells." REPRODUCTION 137, no. 3 (2009): 469–79. http://dx.doi.org/10.1530/rep-08-0343.

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Apoptotic spermatogenic cells and residual bodies are phagocytosed and degraded by Sertoli cells during mammalian spermatogenesis. The meaning of this event remains to be clarified. In this report, we demonstrate that apoptotic spermatogenic cells and residual bodies can be used to produce ATP by Sertoli cells after phagocytosis of them. Sertoli cells produced the highest level of ATP compared with other testicular cells. Phagocytosis assayin vitroshowed that engulfment of apoptotic spermatogenic cells increases ATP production by Sertoli cells. The increased ATP production was detected in semi

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Golat, Brian T., and Don F. Cameron. "Sertoli Cells Enhance Formation of Capillary-Like Structures in Vitro." Cell Transplantation 17, no. 10-11 (2008): 1135–44. http://dx.doi.org/10.3727/096368908787236512.

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Sertoli cells isolated from the testis (referred to as extratesticular Sertoli cells) have been shown to facilitate allo- and xenogeneic cell transplantations. It appears likely that the ability of these cells to enhance the success of cell engraftment is due, in part, to the retention of their intratesticular functions of trophic support and immunoprotection. Sertoli cells also are involved in the regulation of angiogenesis in the testis, which may also contribute to enhanced cell engraftment success facilitated by extratesticular Sertoli cells. Because the maintenance of the cell's intratest

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Griswold, Michael D. "50 years of spermatogenesis: Sertoli cells and their interactions with germ cells." Biology of Reproduction 99, no. 1 (2018): 87–100. http://dx.doi.org/10.1093/biolre/ioy027.

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Abstract The complex morphology of the Sertoli cells and their interactions with germ cells has been a focus of investigators since they were first described by Enrico Sertoli. In the past 50 years, information on Sertoli cells has transcended morphology alone to become increasingly more focused on molecular questions. The goal of investigators has been to understand the role of the Sertoli cells in spermatogenesis and to apply that information to problems relating to male fertility. Sertoli cells are unique in that they are a nondividing cell population that is active for the reproductive lif

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Cameron, D. F., J. J. Hushen, T. Dejarlais, et al. "A Unique Cytoplasmic Marker for Extratesticular Sertoli Cells." Cell Transplantation 11, no. 6 (2002): 507–12. http://dx.doi.org/10.3727/000000002783985530.

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In the absence of a definitive cell marker for testis-derived Sertoli cells, their identification in cell culture or in Sertoli cell-facilitated cell transplantation protocols is difficult and limits the creditable evaluation of experimental results. However, the production by prepubertal Sertoli cells of Mullerian inhibiting substance (MIS) presents the possibility of specifically identifying extratesticular Sertoli cells as well as Sertoli cells in situ, by the immunodection of this unique glycoprotein. This study was designed to determine if isolated rat Sertoli cells could be identified by

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Zhang, Lianjun, Min Chen, Qing Wen, et al. "Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation." Proceedings of the National Academy of Sciences 112, no. 13 (2015): 4003–8. http://dx.doi.org/10.1073/pnas.1422371112.

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Sertoli and Leydig cells, the two major somatic cell types in the testis, have different morphologies and functions. Both are essential for gonad development and spermatogenesis. However, whether these cells are derived from the same progenitor cells and the mechanism regulating the differentiation between these two cell types during gonad development remains unclear. A previous study showed that overactivation of Ctnnb1 (cadherin-associated protein, beta 1) in Sertoli cells resulted in Sertoli cell tumors. Surprisingly, in the present study, we found that simultaneous deletion of Wilms’ Tumor

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Xiong, Weipeng, Yongmei Chen, Huizhen Wang, et al. "Gas6 and the Tyro 3 receptor tyrosine kinase subfamily regulate the phagocytic function of Sertoli cells." REPRODUCTION 135, no. 1 (2008): 77–87. http://dx.doi.org/10.1530/rep-07-0287.

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The apoptotic spermatogenic cells and residual bodies are phagocytosed and degraded by Sertoli cells during spermatogenesis. The mechanisms of this process are largely unknown. Here, we demonstrate that Gas6 and its receptors, the Tyro 3 subfamily of receptor tyrosine kinases (RTKs; Tyro 3, Axl, and Mer), regulate the phagocytic function of Sertoli cells. The phagocytic ability of Sertoli cells increased by five times in the presence of Gas6 in serum-free medium when compared with controls. The Sertoli cells lacking Mer showed a 35% reduction in phagocytosis of apoptotic spermatogenic cells wh

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Wang, Shuai, Pengxiang Wang, Dongli Liang, and Yuan Wang. "BRG1 Is Dispensable for Sertoli Cell Development and Functions in Mice." International Journal of Molecular Sciences 21, no. 12 (2020): 4358. http://dx.doi.org/10.3390/ijms21124358.

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Sertoli cells are somatic supporting cells in spermatogenic niche and play critical roles in germ cell development, but it is yet to be understood how epigenetic modifiers regulate Sertoli cell development and contribution to spermatogenesis. BRG1 (Brahma related gene 1) is a catalytic subunit of the mammalian SWI/SNF chromatin remodeling complex and participates in transcriptional regulation. The present study aimed to define the functions of BRG1 in mouse Sertoli cells during mouse spermatogenesis. We found that BRG1 protein was localized in the nuclei of both Sertoli cells and germ cells in

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Yokonishi, Tetsuhiro, and Blanche Capel. "Differentiation of fetal sertoli cells in the adult testis." Reproduction 162, no. 2 (2021): 141–47. http://dx.doi.org/10.1530/rep-21-0106.

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Sertoli cells proliferate and construct seminiferous tubules during fetal life, then undergo differentiation and maturation in the prepubertal testes. In the adult testes, mature Sertoli cells maintain spermatogonia and support spermatogenesis during the entire lifetime. Although Sertoli-like cells have been derived from iPS cells, they tend to remain immature. To investigate whether Sertoli cells can spontaneously acquire the ability to support spermatogenesis when transferred into the adult testis, we transplanted mouse fetal testicular cells into a Sertoli-depleted adult testis. We found th

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Hadley, M. A., S. W. Byers, C. A. Suárez-Quian, H. K. Kleinman, and M. Dym. "Extracellular matrix regulates Sertoli cell differentiation, testicular cord formation, and germ cell development in vitro." Journal of Cell Biology 101, no. 4 (1985): 1511–22. http://dx.doi.org/10.1083/jcb.101.4.1511.

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Sertoli cell preparations isolated from 10-day-old rats were cultured on three different substrates: plastic, a matrix deposited by co-culture of Sertoli and peritubular myoid cells, and a reconstituted basement membrane gel from the EHS tumor. When grown on plastic, Sertoli cells formed a squamous monolayer that did not retain contaminating germ cells. Grown on the matrix deposited by Sertoli-myoid cell co-cultures, Sertoli cells were more cuboidal and supported some germ cells but did not allow them to differentiate. After 3 wk however, the Sertoli cells flattened to resemble those grown on

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THOMPSON, ERIK W., ALAN W. BLACKSHAW, and SAMIR S. RAYCHOUDHURY. "Secreted Products and Extracellular Matrix from Testicular Peritubular Myoid Cells Influence Androgen‐Binding Protein Secretion by Sertoli Cells in Culture." Journal of Andrology 16, no. 1 (1995): 28–35. http://dx.doi.org/10.1002/j.1939-4640.1995.tb01726.x.

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ABSTRACT: Metabolic cooperation mediated by secreted factors between Sertoli cells and peritubular myoid cells has been well documented. We have confirmed that factors secreted by peritubular myoid cells modulate androgen‐binding protein (ABP) secretion by Sertoli cells and shown further that this can also be achieved with peritubular myoid cell extracellular matrix (ECM). While peritubular myoid cell ECM potentiated the stimulatory effect of dibutyryl cyclic AMP on Sertoli cell ABP secretion, secreted factors did not, suggesting that the two components influence Sertoli cells through distinct

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Dissertations / Theses on the topic "Sertoli cells"

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Wang, Qiufan Claire, and 王秋帆. "Mechanisms of junctional restructuring at the sertoli-sertoli and sertoli-germ cell interfaces during spermatogenesis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B40887686.

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Wang, Qiufan Claire. "Mechanisms of junctional restructuring at the sertoli-sertoli and sertoli-germ cell interfaces during spermatogenesis." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40887686.

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Vija, Lavinia. "Androgen Signaling in Sertoli Cells." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T031/document.

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Les cellules de Sertoli (CS) jouent des rôles essentiels pour la régulation de la spermatogenèse, via la signalisation modulée par le récepteur aux androgènes (RA). Les objectifs de ce travail ont été d’identifier les mécanismes moléculaires de la régulation androgénique et des rôles des partenaires moléculaires dans la régulation androgénique des cellules de Sertoli pendant le développement testiculaire, du fœtus à l’âge adulte, pendant différentes stades du développement. Nous avons caractérisé et étudié une nouvelle lignée immortalisée, mature, de CS, ST38c, présentant une expression substa

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Kadkhodamohammadi, Abdolrahim. "Counting Sertoli Cells in Thin Testicular Tissue." Thesis, Uppsala universitet, Institutionen för informationsteknologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-175237.

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This master thesis develops a novel system to model the tubular structure in thin sections of testicular tissue and count the Sertoli cells. A three-phase method is proposed to model the tubular structure in microscopic images of the tissue, the model is deployed to detect the cells. In the first phase, the germ-mass, which represents the inside layer of tubules, are detected. All cells are detected by radial symmetry transform and then the graph cut algorithm is used to separate the germ cells. Each region covered by a compact set of germ cells is considered as the germ-mass. In the second ph

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Petersen, Cecilia. "Paracrine regulation of Sertoli cell proliferation /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-443-7/.

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Samy, Eileen Teresa. "Regulation of testin and prostaglandin D2 synthetase expression in sertoli cells: a molecular and cell biologystudy and its implication in sertoli-germ cell interactions." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B3122331X.

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Amlani, Shahira R. "Intermediate filaments in Sertoli cells : distribution and possible function." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/27790.

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The distribution of vimentin intermediate filaments in Sertoli cells during spermatogenesis was observed with immunofluorescence, and was confirmed with electron microscopy. The distribution of vimentin filaments within Sertoli cells changes with changes in the germ cell population. At stages where elongate spermatids reside in crypts located deep within the seminiferous epithelium, groups of eight to twelve intermediate filaments were consistently found at the convex surface of the spermatid heads. Here the filaments are in close association with ectoplasmic specializations. At later stages

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Pearce, Kristen (Kristen Joanne) 1974. "Regulation of adhesion between round spermatids and Sertoli cells in the testis." Monash University, Dept. of Obstetrics and Gynaecology, 2003. http://arrow.monash.edu.au/hdl/1959.1/6606.

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Hayes, Marianne Kay. "Bovine testicular cells in vitro: establishment of primary cultures and investigations of secretory functions : a thesis presented for the degree of Doctor of Philosophy in the University of Adelaide." Title page, contents and summary only, 1986. http://web4.library.adelaide.edu.au/theses/09PH/09phh4178.pdf.

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Includes bibliographical references (leaves 98-128). Investigates protein secretion by bovine Sertoli cells in culture. Cultures were obtained from bulls at all stages of post natal development and from sexually mature animals.

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Sneddon, Sharon F. "Oestrogen regulation of gene expression in male germ cells and Sertoli cells." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/29373.

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The aims of this study were to investigate the role of steroid hormones, in particular oestrogens, in murine spermatogenesis. A major focus of these investigations was the role played by ERβ in the modulation of germ cell and somatic cell function. Studies were conducted both using a transformed murine Sertoli cell line (SK11), which has maintained a differentiated Sertoli cell phenotype and spermatogonial stem cells, which were successfully isolated and characterised. ERβ mRNA and protein were shown to be expressed in the SK11 cells both in the undifferentiated and differentiated states. Tran

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Books on the topic "Sertoli cells"

1

Alves, Marco G., and Pedro F. Oliveira, eds. Sertoli Cells. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7698-0.

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D, Griswold Michael, ed. The Sertoli cell. Cache River Press, 1993.

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Dee, Russell Lonnie, and Griswold Michael D, eds. The Sertoli cell. Cache River Press, 1993.

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K, Skinner Michael, and Griswold Michael D, eds. Sertoli cell biology. Elsevier Academic Press, 2005.

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Oliveira, Pedro F., and Marco G. Alves. Sertoli Cell Metabolism and Spermatogenesis. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19791-3.

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Beck, F. F., B. Christ, F. Clascá, et al., eds. Regulation of Sertoli Cell and Germ Cell Differentation. Springer-Verlag, 2005. http://dx.doi.org/10.1007/3-540-29446-5.

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Griswold, Michael D. Sertoli Cell Biology. Elsevier Science & Technology Books, 2014.

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Griswold, Michael D. Sertoli Cell Biology. Elsevier Science & Technology Books, 2014.

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Griswold, Michael D., and Michael K. Skinner. Sertoli Cell Biology. Elsevier Science & Technology Books, 2004.

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Griswold, Michael D. Sertoli Cell Biology. Elsevier, 2018.

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Book chapters on the topic "Sertoli cells"

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Liu, Chao, Jehangir Khan, and Wei Li. "Assessing Autophagy in Sertoli Cells." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7698-0_10.

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Emerich, Dwaine F., Cesario V. Borlongan, and Craig R. Halberstadt. "The Use of Sertoli Cells in Neural Transplantation." In Cell Therapy, Stem Cells, and Brain Repair. Humana Press, 2006. http://dx.doi.org/10.1007/978-1-59745-147-5_9.

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Griswold, M. D., and D. McLean. "Control of Spermatogenesis via Sertoli Cells." In Testicular Tangrams. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-05066-8_6.

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Sanborn, Barbara M., Chung Ying Ku, and Qingxian Lu. "Androgen Action in Sertoli and Peritubular Cells." In Function of Somatic Cells in the Testis. Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2638-3_15.

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Bernardino, Raquel L., Marco G. Alves, and Pedro F. Oliveira. "Establishment of Primary Culture of Sertoli Cells." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7698-0_1.

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Selawry, Helena P. "Sertoli Cells in Islet Transplantation: Testicular Immune Privilege." In Local Immunosuppression of Organ Transplants. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-662-22105-1_19.

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Griswold, Michael D., Leslie Heckert, Tamara Goetz, and Carol Linder. "Expression of the FSH Receptor in the Sertoli Cells." In Function of Somatic Cells in the Testis. Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2638-3_13.

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Freitas, Maria João, and Margarida Fardilha. "Profiling Signaling Proteins in Sertoli Cells by Co-immunoprecipitation." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7698-0_7.

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Dym, M., M. A. Hadley, D. Djakiew, and S. W. Byers. "Differentiation and Polarized Function of Sertoli Cells In Vitro." In Advances in Experimental Medicine and Biology. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5395-9_23.

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Benahmed, M., F. Chuzel, R. Bars, et al. "Role of Sertoli Cells in Hypospermatogenesis Induced by Antiandrogens." In Testicular Tangrams. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-05066-8_2.

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Conference papers on the topic "Sertoli cells"

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Jethwani, Umesh, and Divya Jethwani. "Sertoli cell tumor of ovary: A rare case report." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685324.

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Introduction: Sertoli-Leydig cell tumor (SLCT) is a rare ovarian tumor, Constitute less than 0.5% of ovarian tumors. Most tumors are unilateral, confined to the ovaries. They are seen during the second and third decades of life. They are characterized by the presence of testicular structures that produce androgens. Patients have symptoms of virilization (depending on the quantity of androgen). Case Report: A 42-year-old woman presented Amenorrhea for 14 months. Change in her voice for 1 year and Excessive hair growth on her face, chest, and limbs for the last 2 months. She complained of vague

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Lang, Lang, Ting Zhang, Yu-Bin Ji, and Miao Yu. "Influence of Butyl Benzyl Phthalate and Its Metabolites on Sertoli Cells of Testicle." In 2015 International Conference on Medicine and Biopharmaceutical. WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789814719810_0118.

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Balan, Ion, Dinu Gavojdian, Nicolae Rosca, et al. "Influence of intrinsic and extrinsic factors on somatic and germ cells development." In Conferința științifică națională cu participare internațională "Integrare prin cercetare și inovare", dedicată Zilei Internaționale a Științei pentru Pace și Dezvoltare. Moldova State University, 2025. https://doi.org/10.59295/spd2024n.33.

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Mammalian spermatogenesis is the most complex regulated process of cell development and represents a specific physiological process for the study of the peculiarities of the mechanism of spermatogenesis and for perceiving the basic evolution of all developmental processes, since it involves specific molecular processes of somatic and sex cells. Spermatogenesis generates spermatozoa from spermatogonal stem cells through several stages and comprises spermatocytogenesis, meiosis and spermiogenesis with the continuous unfolding of molecular events of mitosis, meiosis and epigenetic dynamic changes

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Karacaoğlu, Elif. "T-2 Toxin Disrupts Sertoli Cell Barrier via Changes in Tight and Adherent Junctional Proteins in SerW3 Cells." In 15th International Congress of Histochemistry and Cytochemistry. LookUs Scientific, 2017. http://dx.doi.org/10.5505/2017ichc.op-45.

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Korolev, Y. N., L. A. Nikulina, and L. V. Mihaylik. "Ultrastructural analysis of Sertoli cells under the action of low-intensity electromagnetic radiation radiation (experimental study)." In Arbat readings. Знание-М, 2020. http://dx.doi.org/10.38006/907345-01-0.2020.40.44.

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Lima, Marjorie Pinto de Oliveira, Eduarda da Fontoura Moura, Ísis Moukaddem de Souza, et al. "Sertolioma in a Canine: Case Report." In III SEVEN INTERNATIONAL MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/seveniiimulti2023-188.

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Sertolioma is frequent in elderly, non-castrated and cryptorchid dogs, originating from leidig, sertoli and/or seminoma cells, benign and unilateral. The objective of this study was to report the case of a canine, male, 5 years old and cryptorchid, describing the changes caused by the myelotoxicity of hyperestrogenism secondary to sertolioma. The animal showed swelling in the abdominal region, genital hyperpigmentation, pendular foreskin, generalized gynecomastia and cryptorchidism. In the blood count, severe anemia, leukopenia and thrombocytopenia were found. On ultrasound, it was possible to

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Yuniarifa, Conita, Joko Wahyu Wibowo, and Taufiqurrachman Nasihun. "The effect of vitamin C, vitamin E, glutation and zink combination on the number of sertoli and leydig cells: Pre-clinical test in male wistar rats (Rattus norvegicus) exposed to cigarette smoke." In INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND NANO-MEDICINE FROM NATURAL RESOURCES FOR BIOMEDICAL RESEARCH: 3rd Annual Scientific Meeting for Biomedical Sciences. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5109980.

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Ozturk, Ayse Betul, Selcuk Erkilinc, Ilker Cakir, and Sena Ozcan. "771 Gross adnexal mass: sertoli-leydig cell tumor." In ESGO 2024 Congress Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/ijgc-2024-esgo.100.

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Stanton, C. A., C. F. Risquez Cordovez, and S. A. Woods. "Sertoli-Leydig Cell Tumor Presenting as Pseudo-Meigs' Syndrome." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3178.

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Coll, Carla Roura, Ester Miralpeix Rovira, Alvaro Taus Garcia, et al. "732 Sertoli-leydig cell tumour a rare and challenging condition." In ESGO 2024 Congress Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/ijgc-2024-esgo.702.

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