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1

Souza, D. C., D. G. Silva, T. G. Rocha, B. M. Monteiro, G. T. Pereira, L. C. Fiori, R. B. Viana, and J. J. Fagliari. "Serum biochemical profile of neonatal buffalo calves." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 71, no. 1 (February 2019): 187–96. http://dx.doi.org/10.1590/1678-4162-10176.

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ABSTRACT Serum blood samples from 50 Murrah buffalo calves were examined in this study. The animals were allocated into three groups according to the number of parturitions of their mothers: G1 (n= 15) calves from primiparous buffaloes, G2 (n= 19) calves from buffaloes with two to four parturitions, and G3 (n= 16) calves from buffaloes with five or more parturitions. Blood samples were taken at birth, before colostrum ingestion, at 24h, 48h, and 72h after birth, and at 7, 14, 21, and 30 days after birth for determination of levels of gammaglutamyl transferase (GGT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), creatine kinase, total protein, albumin, globulins (including immunoglobulin G), iron, total calcium, ionized calcium, phosphorus, sodium, and potassium. The age of the calves was found to influence all of the biochemical parameters, with the exception of ionized calcium and potassium in the calves in groups G1 and G3. The calving order was found to influence AST, GGT, total protein, albumin, and globulins, including IgG. The high serum ALP activity in the first two days after birth indicates that measurement of the levels of this enzyme may be used as an indirect method of assessing passive immunity transfer.
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Stockham, Steven L. "Interpretation of Equine Serum Biochemical Profile Results." Veterinary Clinics of North America: Equine Practice 11, no. 3 (December 1995): 391–414. http://dx.doi.org/10.1016/s0749-0739(17)30307-3.

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3

Varanis, Laura Ferrari Monteiro, Karla Alves Oliveira, Carolina Moreira Araújo, Wendell Fernando Guimarães da Cruz, and Gilberto de Lima Macedo Júnior. "Serum biochemical reference ranges for pregnant sheep." Bioscience Journal 37 (July 2, 2021): e37036. http://dx.doi.org/10.14393/bj-v37n0a2021-47695.

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Late pregnancy is accompanied by dramatic changes in the metabolism of sheep, in which the nutrient requirements increase and the metabolic capacity of ewes is under severe stress due to the rapid foetal growth and development of the mammary gland. The blood metabolic profile can be used to monitor these alterations, which can lead to metabolic disorders such as pregnancy toxaemia. However, data available on serum parameters in sheep do not consider physiological state. Therefore, the present study aimed to determine the biochemical reference ranges for pregnant ewes, including serum energy, protein and enzyme-related metabolites. Data from a variety of metabolites were obtained from experiments performed in several institutions and commercial farms using Santa Inês, Dorper, Lacaune, Morada Nova, Bergamacia and Suffolk ewes reared under different conditions (grazing, feedlot, semi-feedlot, collective and/or individual pens, and metabolic cages) from 2006 to 2017. All animals were healthy and without feed restriction. Data from ewes with any clinical manifestations were removed. The metabolic energy profile included data of glucose, cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein and very-low-density lipoprotein levels; the metabolic protein profile included the metabolites total protein, uric acid, urea, albumin, and creatinine; and the metabolic enzymatic profile included the enzymes aspartate aminotransferase, gamma-glutamyl transferase and alkaline phosphatase. The reference ranges were estimated using the software RefVal 4.11. Dixon’s test was used to identify and remove outliers. The confidence intervals and percentiles were estimated using the nonparametric method of bootstrap when data were not normally distributed. A 95% confidence level was used. The serum biochemical reference ranges for pregnant sheep determined in our study were strongly divergent from those established by one of the most cited books on the topic, especially considering the high serum urea and cholesterol concentrations and low levels of blood glucose observed. Therefore, it is essential to consider physiological status when evaluating the blood metabolic profile of pregnant ewes in order to maintain an adequate nutritional management and to prevent health disorders that may lead to productive and reproductive losses.
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de Miranda, Renata Lima, Antonio Vicente Mundim, Ana Carolina Silveira Saquy, Álisson Souza Costa, Ednaldo Carvalho Guimarães, Felipe César Gonçalves, and Frederico Ozanam Carneiro e Silva. "Biochemical serum profile of equines subjected to team penning." Comparative Clinical Pathology 18, no. 3 (January 10, 2009): 313–19. http://dx.doi.org/10.1007/s00580-008-0803-6.

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5

Veena, M. P., K. Nagarajan, S. P. Vairamuthu, S. Subapriya, H. Dhanalaksmi, G. P. Kalmath, H. S. Shwetha, and K. Megaha. "Evaluation of Serum Biochemical Profile of Kidney Disorders in Canine." International Journal of Current Microbiology and Applied Sciences 9, no. 3 (March 10, 2020): 700–705. http://dx.doi.org/10.20546/ijcmas.2020.903.084.

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6

Ramesh, D., V. Aswathanarayanappa, G. Kumar, M. Vinuthan, M. Veena, and M. Shivakumar. "Study on Serum Biochemical Profile in Hassan Sheep of Karnataka." International Journal of Livestock Research 8, no. 5 (2018): 98. http://dx.doi.org/10.5455/ijlr.20170411093512.

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Almeida, Adriana Jardim de, Letícia da Silva Leite, Luiz Antônio Eckhardt, Antônio Peixoto Albernaz, Anderson Barros Teixeira, and Karoll Andrea Alfonso Torres. "Serum biochemical profile of emus (Dromaius novaehollandiae) reared in captivity." Journal of Applied Animal Research 46, no. 1 (August 24, 2017): 593–98. http://dx.doi.org/10.1080/09712119.2017.1367686.

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8

Bayir, Abdulkadir, A. Necdet Sirkecioğlu, Harun Polat, and N. Mevlüt Aras. "Biochemical profile of blood serum of siraz Capoeta capoeta umbla." Comparative Clinical Pathology 16, no. 2 (March 13, 2007): 119–26. http://dx.doi.org/10.1007/s00580-006-0663-x.

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9

Acharya, R., and P. B. Pal. "Study of Hematological and Serum Biochemical Profile in Preparturient Murrah Cross Buffaloes in Chitwan District." Nepalese Veterinary Journal 34 (December 21, 2017): 36–40. http://dx.doi.org/10.3126/nvj.v34i0.22892.

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The aim of this study was to establish the reference values for hematology and serum biochemistry of pre-parturient Murrah crossbred buffaloes of Western Chitwan (Bharatpur Metropolitancity). The study was cross-sectional in which31 apparently healthy pregnant Murrah cross buffaloes ranging from 5-8 years were selected randomly after confirmation by rectal palpation. Blood samples collected from jugular vein were stored in EDTA tubes for hematological analysis and for biochemical analysis centrifuged at 1500 rpm for 20 minutes to separate serum after 1 hour of collection. Hematological indices were determined manually using routine laboratory techniques and serum biochemicals were analysed using automated analyzer (Dimension RXL). Serum biochemicals like Glucose, BUN, Creatinine, Calcium, Phosphorous, Magnesium, AST, ALT, total serum Protein and albumin level were found within the normal range. Similarly, hematologic indices Hb, PCV, Platelet counts, RBC counts, WBC counts, and differential leukocyte counts were also in normal ranges. However, eosinophil (7.83±0.82), and monocyte (4.4±0.53) counts were higher at significant numbers which suggests gastrointestinal parasitic infestations and/or allergic diseases along with some chronic infectious diseases in the buffalo herd of Bharatpur Metropolitancity in western Chitwan.
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10

Wardoyo, Suwaji Handaru, and Solichan Badri. "Effect Acupuncture for Low Back Pain; Biochemical and Protein Profile Analysis." Jurnal Kesehatan Masyarakat 16, no. 2 (November 29, 2020): 207–15. http://dx.doi.org/10.15294/kemas.v16i2.22650.

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Low back pain (LBP) is one of the common symptoms experienced by some of the world community. Acupuncture as a method of healing a disease offers a solution for LBP symptom. This study aimed to determine the effect of acupuncture with local and Yamamoto New Scalp Acupuncture (YNSA) points with biochemical analysis related to total protein, albumin, and globulin, and analysis of blood serum protein profiles using the SDS-PAGE method. This research was conducted using sterile acupuncture needles that inserted in patients with several local points, namely BL22 (Sanjiaoshu), BL23 (Shenshu), BL24 (Qihaishu), BL25C (Dachangshu), and BL26C (Guanyuanshu) and combined with the YNSA points through somatotope D points and extra lumbar points H and I. Blood serum was collected for total protein, albumin, and globulin analysis. That blood serum was also used for protein profile analysis using Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE) method. The results showed that six times of acupuncture treatments gave positive correlation in total protein, albumin, and globulin. Analysis of blood serum protein profiles using SDS-PAGE showed a protein band of about 12 KDa and it might be a interleukin-13 protein. The results were expected can be useful as scientific information especially related to acupuncture for LBP treatment and this of about 12 KDa protein band can be used as biomarker candidates for the symptoms.
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11

Shah, Faridullah, Naseeb Ur Rehman, Zakia Khan, Rafat Ullah, and Wasim Ahmad. "Biochemical assessment of iron profile in type 2 diabetes patients." Professional Medical Journal 27, no. 08 (August 10, 2020): 1590–94. http://dx.doi.org/10.29309/tpmj/2020.27.08.4212.

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Objectives: Iron profile is considered to be an important guide for improved health around the globe. An altered iron profile is a risk factor for numerous diseases. Extreme iron accretion in body results in damaging many cellular structures as well as in oxidative damage with many complications. Thus, iron profile must be considered in many ailments including DM. Study Design: Descriptive study. Setting: Department of Biochemistry, BMC Bannu and Department of Medicine, KGN Teaching Hospital Bannu-KPK. Period: January 2019 to June 2019. Material & Methods: 140 subjects were taken in this study, out of which 70 were suffering from type 2 diabetes and 70 were normal healthy controls. BMI was calculated by dividing body weight (Kg) to square of height (meters). The waist / hip circumference ratio was calculated by dividing the waist circumference (cm) to hip circumference (cm). Sphygmomanometer was used for blood pressure measurement. The serum iron, TIBC, UIBC, plasma glucose and HbA1c were measured by semi-auto analyzer. The serum ferritin was estimated by chemiluminescence method. The % transferrin saturation was calculated by formula serum iron (μg/dl) x 100/ TIBC (μg/dl). Result: The anthropometric parameters like weight, BMI, waist circumference, hip circumference, waist hip circumference ratio, systolic and diastolic blood pressure was statistically extremely significantly (p<0.001) increased in type 2 diabetes mellitus subjects as compared to healthy control subjects. The plasma fasting glucose, HbA1C, serum iron, % saturation and serum ferritin were statistically extremely significantly (p<0.001) increased and UIBC was statistically extremely significantly (p<0.001) decreased while TIBC and hemoglobin were statistically significantly (p<0.05) decreased in type 2 diabetes mellitus subjects as compared to healthy control subjects. Conclusion: Elevated iron and ferritin is a risk factor for diabetes and produce many complications. Proper management must be taken to remove the excess iron that can be very harmful to the body.”
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12

Nahar, Khairun, Gazi Mahfuza, Shirin Akhter Begum, Khodeza Khatun, and Md Rafiqul Islam. "Clinical, Biochemical and Hormonal Profile of Polycystic Ovary Syndrome." Journal of National Institute of Neurosciences Bangladesh 3, no. 2 (May 26, 2018): 94–98. http://dx.doi.org/10.3329/jninb.v3i2.36773.

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Background: The polycystic ovary syndrome is a heterogenous condition, the pathophysiology of which is multifactorial. It is considered as a systemic and metabolic disorder like hyperglycemia and insulin resistance with increased risk of type II diabetes mellitus and cardiovascular diseases.Objective: The purpose of the present study was to analyze the clinical, biochemical and hormonal profile of patients PCOS and to find out correlations among them.Methodology: This cross-sectional observational study was done including 100 diagnosed cases of PCOS attending the GOPD, BSMMU Hospital. This study was done to analyze the clinical, biochemical and hormonal characteristics of PCOS patients and to observe the correlations among them.Result: The mean age of study populations was 22.7± 6.9 years and more than half of them were overweight or obese. Menstrual abnormality like oligomenorrhoea and secondary amenorrhoea was found in 95% cases and 5% were eumenorrhic. Prevalence of hirsutism and subfertility was 69% and 50% respectively. More than half (52%) of cases had LH/FSH ratio >2 which is taken to be significant. About one-third (30%) of cases had total testosterone level above the reference range with a mean value of serum testosterone 71.4±27.9 ng/dL.Conclusion: Significant positive correlation was found among increased BMI, increased LH/FSH ratio, serum testosterone and serum TSH level. Further studies are needed to corroborate our findings and to find out the clinical, biochemical and endocrinological characteristics of our women of PCOS.Journal of National Institute of Neurosciences Bangladesh, 2017;3(2): 94-98
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13

Sasikala, V., B. Naik, L. Reddy, A. Sivakumar, and J. Samhitha. "Serum Biochemical Values and Haematological Profile of Farm Emus (Dromaius novaehollandiae)." International Journal of Livestock Research 8, no. 5 (2018): 343. http://dx.doi.org/10.5455/ijlr.20180328061829.

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14

Sivanagendra Babu, B., M. V. A. N. Suryanarayana, E. Raghava Rao, and P. Asha Latha. "Effect of Feed Restriction on Serum Biochemical Profile in Ram Lambs." International Journal of Current Microbiology and Applied Sciences 7, no. 03 (March 10, 2018): 925–30. http://dx.doi.org/10.20546/ijcmas.2018.703.109.

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15

Hossain, MB, MN Islam, AH Shaikat, MG Yasin, MM Hassan, SKMA Islam, A. Rahman, MA Mamun, and SA Khan. "Biochemical profile of wild-captured Indian Flying Fox (Pteropus giganteus) in Bangladesh." Bangladesh Journal of Veterinary Medicine 11, no. 1 (January 19, 2014): 75–79. http://dx.doi.org/10.3329/bjvm.v11i1.17095.

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Bats of the genus Pteropus (P.) under the class Mammalia are important ecologically as pollinators, but little is known about their basic physiology. For this, serum biochemical values of healthy wild captured frugivorus bats (P. giganteus) were determined for providing baseline information and health care assessments in zoological setting. Ninety clinically healthy large frugivorous bats were captured from the wild and anesthetized for 2 hours following capture for blood collection from brachial vein. Serum glucose, total protein (TP), triglyceride (TG), cholesterol, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine phosphokinase (CPK), urea, uric acid, calcium and phosphorus were determined using biochemical analyzer. No major differences were observed in the serum biochemical values between male and female bats, juvenile and adults or fair and good health-state bats except significant variation in the AST (p < 0.05), ALP (p < 0.05) and CPK (p < 0.05) between adult and juvenile bats, calcium (p< 0.01) and phosphorus (p < 0.01) between the good and fair health-state bats. The values from this study can be used to create reference intervals of serum biochemistry of bat found in Indian subcontinent, and they can make up the first comprehensive biochemical study for this highly endangered species. DOI: http://dx.doi.org/10.3329/bjvm.v11i1.17095 Bangl. J. Vet. Med. (2013). 11 (1): 75-79
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Tavazzi, Barbara, Anna Paola Batocchi, Angela Maria Amorini, Viviana Nociti, Serafina D'Urso, Salvatore Longo, Stefano Gullotta, Marika Picardi, and Giuseppe Lazzarino. "Serum Metabolic Profile in Multiple Sclerosis Patients." Multiple Sclerosis International 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/167156.

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Multiple sclerosis (MS) is a progressive demyelinating process considered as an autoimmune disease, although the causes of this pathology have not been yet fully established. Similarly to other neurodegenerations, MS is characterized by a series of biochemical changes affecting to different extent neuronal functions; great attention has been given to oxidative/nitrosative stress and to alterations in mitochondrial functions. According to previous data, MS patients show significant changes in the circulating concentrations of different metabolites, although it is still unclear whether uric acid undergoes to decrease, increase, or no change under this pathological condition. In this study, we report the serum metabolic profile in terms of purines, pyrimidines, creatinine, malondialdehyde, ascorbic acid, nitrite, and nitrate in a group of 170 MS patients. The results show increase in circulating uric acid and other oxypurines (hypoxanthine and xanthine), as well as in uridine and β-pseudouridine. The concomitant increase in circulating creatinine, malondialdehyde, nitrite, and nitrate, and decrease in ascorbic acid, demonstrates that MS induces alteration in energy metabolism and in oxidants/antioxidants balance that can be monitored in serum of MS patients.
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Saravanan, S., V. Umapathi, M. Priyanka, M. Hosamani, B. P. Sreenivasa, B. H. M. Patel, K. Narayanan, Aniket Sanyal, and S. H. Basagoudanavar. "Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus." Veterinary World 13, no. 3 (2020): 426–32. http://dx.doi.org/10.14202/vetworld.2020.426-432.

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Background and Aim: Foot-and-mouth disease (FMD) is an acute viral infection affecting cloven-hoofed animals causing vesicular erosions in the oral cavity and interdigital space. The present study was undertaken to ascertain the time-dependent changes in clinical, hematological, and biochemical profiles in different breeds of cattle following experimental infection. Materials and Methods: The animals were inoculated with 1.0×104 50% bovine tongue infectious dose (BTID50) by intradermolingual route. Clinical signs were observed, and blood/serum samples were collected at different time intervals. Results: The white blood cell count declined sharply on days 7-13 and recovered on day 14 post-FMD infection. Biochemical analysis of serum markers for vital organ profile revealed no marked damage. However, a significant increase in blood urea nitrogen (BUN) value indicated pre-renal azotemia. Transient hyperthyroidism was indicated by the rise in T3 and T4 that can be correlated with a decrease in triglyceride and total cholesterol levels. In the cardiac damage assessment study, a distinct breed difference was observed wherein Malnad Gidda calves showed no cardiac damage. Conclusion: Except thyroid profile, BUN, and creatine kinase-myocardial band, all other serum biochemical parameters showed no significant abnormalities, whereas lymphopenia is the only hematological change and it is suggested that effective ameliorative measures should be targeted mainly on the feed/water intake, thyroid gland, and the level of lymphocytes.
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Eke, IG, UU Eze, IO Ezeh, TA Nzeakor, AO Anaga, and PA Onyeyili. "Effects of secnidazole-diminazene aceturate combination therapy on parasitaemia and serum biochemical profile after late treatment in Trypanosoma brucei brucei infected dogs." Veterinární Medicína 65, No. 12 (December 13, 2020): 543–52. http://dx.doi.org/10.17221/150/2019-vetmed.

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Relapse parasitaemia is a major setback in the chemotherapy of a late stage Trypanosoma brucei brucei infection. An aberrant serum biochemical profile resulting from a T. b. brucei infection in dogs has been attributed to multiple organ injuries resulting from the invasive nature of the organism. Therapy with diminazene aceturate alone has not been satisfactory. This study evaluated the effects of a secnidazole-diminazine aceturate (SEC-DA) combination therapy on parasitaemia and the serum biochemical profile after the late treatment of a T. b. brucei infection in dogs. Eighteen dogs were randomly assigned to 6 groups (n = 3) as follows: Group A: uninfected nor treated; group B: infected without treatment; group C: infected and treated with DA (3.5 mg/kg) (DA-monotherapy) intramuscularly (i.m.) once; group D: infected and treated with SEC (100 mg/kg) and DA (3.5 mg/kg); group E: in-fected and treated with SEC (200 mg/kg) and DA (3.5 mg/kg) and group F: infected and treated with SEC (400 mg/kg) and DA (3.5 mg/kg). Secnidazole was administered orally for 5 days while DA was given i.m. once in groups D–F. The dogs were infected with 5 × 10<sup>5</sup> trypanosomes intraperitoneally and treatment started 14 days post-infection. The parasitaemia was monitored daily while the serum biochemical indicators were monitored 14, 21, and 28 days post-infection. The total aparasitaemia was achieved in the SEC-DA treated dogs 72 h post-treatment and in 86 h in the DA-monotherapy dogs. A relapse parasitaemia occurred in the DA-monotherapy dogs 17 days post-treatment. The SEC-DA combination therapy caused a significant (P &lt; 0.05) decline in the hitherto elevated urea and creatinine concentrations, and the ALP, ALT, AST activities. Also, there was a significant (P &lt; 0.05) increase in the previously decreased serum albumin in the SEC-DA treated dogs. In conclusion, secnidazole-diminazene aceturate combination therapy prevented the relapse parasitaemia and ameliorated aberrant serum biochemical profiles of T. b. brucei infected dogs after late treatment.
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Nozdrin, G. A., E. R. Rafikova, and M. S. Yakovleva. "Hematological and serum biochemical profile of broilers during treatment with Vetom 21.77." Research Journal of Pharmacy and Technology 12, no. 8 (2019): 3739. http://dx.doi.org/10.5958/0974-360x.2019.00640.1.

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DiBartola, SP. "Interpretation of Metabolic Acid Base Disturbances Using the Routine Serum Biochemical Profile." Journal of Feline Medicine and Surgery 3, no. 4 (December 2001): 189–91. http://dx.doi.org/10.1053/jfms.2001.0142.

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Velayudhan, Jithin Mullakkalparambil. "Hemato-biochemical and Serum Iron Profile Study in Dogs with Hemoprotozoal Infection." Advances in Animal and Veterinary Sciences 3, no. 4 (2015): 200–206. http://dx.doi.org/10.14737/journal.aavs/2015/3.4.200.206.

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22

Narasimhan, Denesh, and Silpita Katragadda. "Retrospective analysis of biochemical profile of dengue infection in a tertiary care hospital." International Journal of Research in Medical Sciences 5, no. 12 (November 25, 2017): 5218. http://dx.doi.org/10.18203/2320-6012.ijrms20175131.

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Background: Dengue is an exceedingly common infection of the tropics. The aim of the research to study the biochemical parameters of serologically proven dengue cases.Methods: The study included Dengue patients admitted in PSG Hospital between January 2011and December 2012.Results: Analysis of aspartate aminotransferase results showed that 19.1% had two-fold rise, 13.3% had three-fold rise and 19.6% had more than threefold rise. Analysis of alanine aminotransferase showed that 35.7% had normal values, 14.95% had two-fold rise, 11.1% had three-fold rise and 11.5% had more than threefold rise. Serum proteins were normal in 35.7% and low in 19.6%. Analysis of serum albumin showed low values in 10.6% Serum sodium levels were low in 11.1% of patients. Albuminuria was positive in 53% of patients. Serum ionised calcium levels were low in 26.8% of patients.Conclusions: The biochemical abnormalities noted in our study included include elevated liver enzymes, low sodium and ionised calcium levels, hypoalbuminemia and increased urine albumin excretion.
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Rufino, João Paulo Ferreira, Frank George Guimarães Cruz, Ramon Duque Melo, Julmar Da Costa Feijó, Lucas Duque Melo, Ana Paula Guimarães Cruz Costa, and Natalia Dos Santos Bezerra. "Brazil nut oil in diets for breeder cocks." Acta Scientiarum. Animal Sciences 40 (December 27, 2017): 37472. http://dx.doi.org/10.4025/actascianimsci.v40i0.37472.

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This study aimed to evaluate the inclusion of Brazil nut oil in diets for breeder cocks on performance, semen analyses, biochemical serum profile and testicular morphology. Forty-two Rhode Island Red breeder cocks with 40 weeks of age were used. The experimental design was completely randomized consisting of seven levels of Brazil nut oil (0; 0.30; 0.60; 0.90; 1.20; 1.50 and 1.80%) in the diets. Data collected were evaluated by polynomial regression. Differences (p < 0.05) were detected in feed conversion, semen volume, motility, vigor, pH, swirling and concentration, in which the inclusion of Brazil nut oil in the diets improved the reproductive performance. Differences (p < 0.05) were also detected in the biochemical serum profile (triglycerides, cholesterol and blood pH); the inclusion of Brazil nut oil caused a large increase in blood triglycerides and cholesterol levels, consequently, changing the blood pH. The Brazil nut oil can be used as an energetic additive in diets given to breeder cocks, promoting better reproductive performance, without changing semen and testicular morphology, but altering the biochemical serum profile of the birds.
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Begum, Ferdousi. "Clinical and Hormonal Profile of Polycystic Ovary Syndrome." Journal of South Asian Federation of Obstetrics and Gynaecology 1, no. 2 (2009): 22–25. http://dx.doi.org/10.5005/jp-journals-10006-1023.

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ABSTRACT Objectives The objectives of the study were to find out the clinical features, biochemical and hormonal profile of patients with polycystic ovary syndrome (PCOS) in Bangladesh. Material and Methods A case control and cross-sectional study was undertaken among 78 PCOS patients attending infertility clinic and 33 controls at BIRDEM Hospital, Dhaka. Inclusion criteria for cases were oligo/amenorrhea, transvaginal sonography suggesting PCO and/ or features of hyperandrogenemia with exclusion of other causes. Controls were women with regular menstrual cycle. Results Age and height of cases and controls were similar. BMI >25 was 67% among cases and 19% among controls (P<0.001); waist hip ratio >0.8 was 64% among cases and 29% among controls (P<0.001). Mean BMI of cases was 28.2 + 4.5 and that of cases was 21.05 + 4.1; mean fasting glucose among cases was 5.93 + 1.08 and among controls was 4.4 + 1.11 mmol/L (P<0.01); mean fasting serum insulin level was 32.15+ 12.13 among cases was 11.32 +10.02 ìU/ml among controls(P<.001); insulin resistance (fasting HOMA-IR>6.8) was 42.32% in cases and 12% in control (P<.001). Patients with PCOS had following clinical and biochemical parameters: oligomenorrhea- 74%, amenorrhea- 26%, mean Ferriman-Galaway score -19.89 + 5.06. At day 3 of menstrual cycle meanserum LH was 12.79+7.1 mmol/L, serum FSH was 5.23 + 2.5 miu/ml and serum prolactin was 415.15+180.5 mmol/L; 30% had biochemical hyperandrogenemia. Conclusions PCOS patient in Bangladesh are usually overweight, hirsute (grade I and II), hyperandrogenemic, insulin resitant and have altered LH to FSH ratio.
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Giang, Nguyen, Nguyen Hien, Huynh Loan, Phan Phuc, Nguyen Dai, Takeshi Shimogiri, and Do Khoa. "Serum biochemical properties of Vietnamese indigenous Noi chicken at 56 days old." Biotehnologija u stocarstvu 36, no. 3 (2020): 329–39. http://dx.doi.org/10.2298/bah2003329g.

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Serum profile is generally considered as comprehensive data which directly reflected animal health and their potential resistance to environmental, nutritional and pathological stress. The present study aimed to provide physiological reference values for selected biochemical parameters in Noi chickens, a famous Vietnamese native breed, at 56 days old. The collected blood samples of 355 Noi birds (164 males and 191 females) were used to evaluate biochemical serum profile. Glucose, total protein, albumin, globulin, albumin/globulin ratio, triglycerides, cholesterol, creatinine, and uric acid in the serum were measured. The variation in these values arising from different sexes was also investigated. The results indicated that there were no differences (P>0.05) in the assessed indices between male and female Noi chickens. In overall for the whole group, these values were obtained as 250.86 mg/dL, 7.34 g/dL, 3.40 g/dL, 3.94 g/dL, 1.75, 148.54 mg/dL, 190.86 mg/dL, 0.44 mg/dL, and 1.44 mg/dL, respectively. The relationship among the biochemical parameters showed relatively low coefficients (r=0.79 in maximum). The females obtained higher correlation coefficients between levels of total protein and glucose (r=0.42) as well as between total protein and globulin (r=0.79), compared to the males. It was concluded that the male and female chickens performed similar values of serum indices. The contribution of this study might expand the knowledge on the biochemical profile and improved breeding strategies of Vietnamese indigenous Noi chickens.
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Varanis, Laura Ferrari Monteiro, Erica Beatriz Schultz, Karla Alves Oliveira, Luciano Fernandes Sousa, Wendell Fernando Guimarães da Cruz, and Gilberto de Lima Macedo Junior. "Serum biochemical reference ranges for lambs from birth to 1 year of age in the tropics." Semina: Ciências Agrárias 42, no. 3Supl1 (April 22, 2021): 1725–40. http://dx.doi.org/10.5433/1679-0359.2021v42n3supl1p1725.

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The study aimed to determine the biochemical reference ranges for lambs from birth to 1 year of age in the tropics. Data were obtained from experiments performed in several institutions and commercial farms using Santa Inês, Dorper, Lacaune, Morada Nova, Bergamacia and Suffolk lambs reared under different conditions (grazing, feedlot, semi-feedlot) from 2006 to 2017. Serum energy-, protein-, mineral-, and enzyme-related metabolites were evaluated. The metabolic energy profile included data from glucose, cholesterol, triglycerides, fructosamine, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and very-low-density lipoprotein cholesterol; the metabolic protein profile included total protein, uric acid, urea, albumin, and creatinine; the metabolic mineral profile included data on calcium, phosphorus, and magnesium; and the metabolic enzymatic profile included the enzymes aspartate aminotransferase, gamma-glutamyl transferase, alkaline phosphatase, and creatine kinase. The reference ranges were estimated using confidence intervals with a 95% confidence level, and percentiles were estimated or bootstrapped nonparametrically when the data were not normally distributed. The serum biochemical reference ranges determined for lambs are strongly divergent from those established by one of the most cited books on the topic, especially considering the high serum urea and cholesterol concentrations and low levels of blood glucose observed. Therefore, the serum biochemical reference ranges for lambs from birth to 1 year of age in the tropics differ from international data, which consider adult sheep in temperate climate zones.
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Thasmi, Cut Nila, Husnurrizal Husnurrizal, Muslim Akmal, Sri Wahyuni, and Tongku Nizwan Siregar. "THE BLOOD BIOCHEMICAL PROFILE IN ACEH COWS WITH REPEAT BREEDING." Jurnal Veteriner 22, no. 1 (March 31, 2021): 26–32. http://dx.doi.org/10.19087/jveteriner.2021.22.1.26.

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Tujuan penelitian ini adalah mengetahui profil biokimia darah sapi aceh yang mengalami kawin berulang/repeat breeding (RB). Dalam penelitian ini digunakan 16 ekor sapi aceh yang terdiri atas tujuh ekor sapi aceh fertil dan sembilan ekor sapi aceh RB, yang berumur 3-8 tahun dengan skor kondisi tubuh (SKT) 3-4. Koleksi serum dilakukan untuk pemeriksaan profil biokimia darah meliputi kadar kolesterol, protein, dan glukosa. Kadar kolesterol; protein; dan glukosa sapi aceh fertil vs RB masing-masing adalah 185,86±45,34 vs 144,00±40,69 mg/dL; 6,57±1,55 vs 6,96±2,05 g/dL; dan 67,43±13,72 vs 73,78±15,83 mg/dL. Disimpulkan bahwa kadar glukosa sapi aceh RB lebih tinggi dibandingkan sapi fertile, sedangkan kadar kolesterol dan protein relatif sama.
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Faridi, M. M. A., Anju Aggarwal, Manish Kumar, and Abedin Sarafrazul. "Clinical and biochemical profile of dengue haemorrhagic fever in children in Delhi." Tropical Doctor 38, no. 1 (January 2008): 28–30. http://dx.doi.org/10.1258/td.2007.006158.

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The clinical and biochemical profile of dengue haemorrhagic fever (DHF) varies from epidemic to epidemic. We studied children hospitalized with DHF from September 2003 to December 2003. All were diagnosed, managed and monitored according to a standard protocol. Of the 34 who fulfilled the World Health Organization criteria of DHF, 22 (64.6%) were male. All patients presented with fever and hepatomegaly. Examination also revealed splenomegaly in 11 (32.4%), ascites in 6 (17.6%) and pleural effusion in 3 (8.8%). Common bleeding manifestations were positive tourniquet test in 22 (64.7%) and epistaxis in eight (23.5%). Most children had a platelet count of between 20,000/mm3 and 50,000/mm3 (56%). Bleeding manifestations were not related to platelet count (P > 0.05). Serum glutamic pyruvic transaminase (SGPT) >40 IU/L was seen in 22 (64.6%) patients, alkaline phosphate (ALP) >400 IU/L in 12 (35.3%) and serum bilirubin >1 mg% in 3 (8.8%). IgM dengue serology was positive in 68.5% cases. There was no significant difference in liver function tests with or sex ( P > 0.05). Clinical features of DHF varied from the previous epidemic. Hepatic dysfunction with increased levels of serum enzymes was common in DHF.
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Dv, Krishna Veni, Neetha Kundoor, Srilatha Bashetti, and Prashnathi Rayaprolu. "ALTERED LIPID PROFILE IN HYPOTHYROIDISM: A BIOCHEMICAL VIEWPOINT." Asian Journal of Pharmaceutical and Clinical Research 11, no. 7 (July 7, 2018): 64. http://dx.doi.org/10.22159/ajpcr.2018.v11i7.24277.

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Context: Overt hypothyroidism is the most common endocrine disorder associated with a decrease in 3,5,3’-triiodothyronine and 3,5,3’,5’-tetraiodothyronine levels and increase in thyroid-stimulating hormone (TSH) levels. Thyroid hormones (THs) regulate all major metabolic pathways. THs play an important role in the synthesis, metabolism, and transport of lipids. Thyroid failure is associated with various biochemical and molecular alterations. Hypothyroidism is the common cause of secondary dyslipidemia as well as cardiovascular risk.Objective: The present review focuses on alterations in lipid metabolism associated with hypothyroidism leading to cardiovascular risk.Methods: The data source is from PUBMED, Google Scholar, and EMBASE. The study is a part of our previous research in studying the variations in lipid profile and transaminases in overt hypothyroidism.Result: The serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apo B), lipoprotein (a) (Lp[a]), and triglycerides are elevated in individuals with overt hypothyroidism. In addition, it was also observed that the endothelial dysfunction, normal/depressed systolic function, left ventricular diastolic dysfunction at rest, as well as systolic and diastolic dysfunction on effort was observed in hypothyroidism.Conclusion: THs play an important role in the regulation of lipid metabolism. Hypothyroidism is also linked with altered hemodynamics. The atherogenic lipid profile along with other predisposing factors may contribute to the coronary artery disease.
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FYTIANOU (Α. ΦΥΤΙΑΝΟΥ), A., M. SARIDOMICHELAKIS (Μ. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ), A. F. KOUTINAS (Α. Φ. ΚΟΥΤΙΝΑΣ), N. ROUBIES (Ν. ΡΟΥΜΠΙΕΣ), and Z. POLIZOPOULOU (Ζ. ΠΟΛΥΖΟΠΟΥΛΟΥ). "Reference values of the usual biochemical profile in clinically normal cats." Journal of the Hellenic Veterinary Medical Society 49, no. 3 (January 31, 2018): 204. http://dx.doi.org/10.12681/jhvms.15776.

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The purpose of this study was the establishment of "reference values" for the commonly used blood serum constituents in the everyday practice. A total number of 23 parameters including total proteins, albumin, globulin, albumin/globulin ratio, urea nitrogen (BUN), creatinine, glucose, cholosterol, triglycerides, total and indirect bilirubin, alkaline phosphatase (AP), gamma - glutamylotransferase (γ-GT), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lipase, amylase, creatinine kinase (CK), lactate dehydrogenase (LDH), calcium (Ca), phosphorus (P), potassium (K) and sodium (Na) in the serum samples obtained from 1ΘΘ clinically normal cats equally distributed into two age groups (group A <12 months, group Β >12 months). For the total number of sampled cats and for each age group the mean, the standard deviation, the actual range and the 95% confidence interval were calculated separately. Statistical analysis revealed significant differences between young and adult cats (group A - group B) for as many as 13 parameters. As it was expected our results are both in agreement and disagreement with those reported in the relevant veterinary literature.
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AL-Salmany, Alaa K. M. "Determination of reference values of some serum biochemical parameters of healthy Donkeys in Iraq." Iraqi Journal of Veterinary Medicine 40, no. 2 (January 5, 2017): 57–60. http://dx.doi.org/10.30539/iraqijvm.v40i2.112.

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This study is conducted to establish the profile of some serum biochemicals which included creatinine, urea, glucose, total protein and albumin concentrations in 104 clinically normal donkeys (65 males and 39 females) aged 2-4 years. Animals were classified on the basis of age and sex, in Baghdad city/ Iraq. The Results showed that the, mean values ± standard error (SE) of serum creatinine and urea concentrations were as follows: Creatinine 65.55±2.01 µmol/L and urea 6.79±0.20 mmol/L, while serum concentrations of glucose, total protein and albumin were 54.7±3.09 g/dl, 123±14.3 and 3.4±0.08 mmol/L, respectively. Creatinine values showed a significant difference between 4 years and more than 4 years old subgroups. However, there were no differences in serum urea concentration between male and female and compared with biochemical ranges obtaining for another donkey breeds. This suggested that most biochemical values determined in this study serve as reference ranges for Iraqi donkey and could be used in health control and diagnosis of diseases. In conclusion a significant increase in serum creatinine was recorded at age 4 and more than 4 years as compares with serum urea and no differences in serum glucose, total protein and albumin.
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Jeong, Tae-Dong, Woochang Lee, Sung-Eun Choi, Jae Seung Kim, Hong-Kyu Kim, Sung Jin Bae, Sail Chun, and Won-Ki Min. "Relationship between Serum Total Cholesterol Level and Serum Biochemical Bone Turnover Markers in Healthy Pre- and Postmenopausal Women." BioMed Research International 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/398397.

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Background. The presence of common risk factors suggests that there is a relationship between osteoporosis and cardiovascular disease, possibly via dyslipidemia and inflammation. We investigated the relationships among the lipid profile, the inflammation marker high-sensitivity C-reactive protein (hsCRP), bone turnover markers, and bone mineral density (BMD) to assess the correlation between osteoporosis and cardiovascular disease and identify factors predicting osteoporosis.Methods. The study included 759 Korean women older than 20 years of age. The BMD, serum lipid profile, and levels of hsCRP, cross-linked C-terminal peptide (CTX), and osteocalcin were measured. We compared the serum biomarkers between groups with normal and low BMD and assessed the correlations between the levels of bone turnover markers and the lipid profile and hsCRP level.Results. The concentrations of CTX, osteocalcin, and total cholesterol were significantly higher in the low BMD group than in the normal BMD group in premenopausal women group. However, hsCRP was not correlated with these parameters. Multivariate logistic regression analysis revealed that TC (OR, 1.647; 95% CI, 1.190–2.279) and osteocalcin (OR, 1.044; 95% CI, 1.002–1.088) had an increased risk of low BMD in premenopausal women.Conclusions. These results indicate that total cholesterol concentration is correlated with the levels of bone turnover markers, suggesting that it might predict osteoporosis in premenopausal women.
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Alves, Benner G., Kele A. Alves, Muller C. Martins, Lucas S. Braga, Thiago H. Silva, Bruna G. Alves, Ricarda M. Santos, et al. "Metabolic profile of serum and follicular fluid from postpartum dairy cows during summer and winter." Reproduction, Fertility and Development 26, no. 6 (2014): 866. http://dx.doi.org/10.1071/rd13102.

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This study was designed to monitor the biochemical profiles of serum and follicular fluid (FF) of postpartum dairy cows during the summer (n = 30) and winter (n = 30). Blood and FF (follicles ≥ 9 mm) were obtained from Girolando cows at 30, 45, 60, 75 and 90 days postpartum. The samples were collected and analysed to determine glucose, total cholesterol (TC), triglyceride (TG), urea, sodium (Na), potassium (K) and calcium (Ca) levels. Throughout the study, the following clinical variables were measured: rectal temperature (RT), respiratory rate (RR) and body condition score (BCS). In addition, the temperature humidity index (THI) was calculated for each season. During the summer season, THI was higher, BCS decreased, there was an increase in RT, and glucose, urea, Na and K serum levels were decreased (P < 0.05). The levels of TC, TG, urea, K and Ca in follicular fluid increased (P < 0.05). Positive correlations (P < 0.05) were observed between the serum and FF levels for glucose (r = 0.29), TC (r = 0.24) and Ca (r = 0.30). Therefore, the biochemical profile of serum and FF of dairy cows under summer heat-stress conditions demonstrates marked changes that may impair fertility during lactation.
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34

Brelaz, K. C. B. T. R., F. G. G. Cruz, J. P. F. Rufino, R. J. M. Brasil, A. F. Silva, and A. N. A. Santos. "Serum biochemistry profile of laying hens fed diets with fish waste oil." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 73, no. 1 (February 2021): 223–30. http://dx.doi.org/10.1590/1678-4162-11704.

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ABSTRACT The present study aimed to evaluate increasing levels of fish waste oil in diets for laying hens on serum biochemistry profile. 192 Hisex White laying hens at 29 weeks of age were used, with water and food ad libitum. The experimental design was completely randomized consisting of eight treatments corresponding to the inclusion levels of fish waste oil (0, 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 and 3.5%) in the diets, with four replicates of six birds each. Data collected were subjected to polynomial regression at 5% of significance. Significant differences (P<0.05) were observed in triglycerides, glucose, total cholesterol, and uric acid. These parameters presented a decrease when hens fed diets with higher level of fish waste oil. The results of the present study indicated that the inclusion of fish waste oil caused a significant effect in the serum biochemical profile of laying hens, especially in glucose, triglycerides, total cholesterol, and uric acid concentrations. The inclusion level of 3.5% of fish waste oil caused larger disequilibrium in the serum biochemical profile of laying hens.
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35

Rydzyk, Artur, Jan Błaszczyk, and Rafał Rydzyk. "The Influence of Low-Frequency Vibrations on the Lipid Profile in Women." Acta Balneologica 61, no. 1 (January 2019): 24–28. http://dx.doi.org/10.36740/abal201901104.

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Introduction: The aim of this dissertation is an evaluation of the effect of low frequency vibration on serum lipid profiling women. Materials and Methods: A group of females aged 28-64 years old were assessed twice, before and after 19 days of exposure to low frequency vibration. The parameters of the vibration used (frequency and amplitude) and the short exposition time were selected in order to comply with standards established to safeguard human health; mechanical stimulus safe for human health according to the Polish Standard PN EN ISO 2631-1:1997. The parameters used were as follows: frequency 3.5Hz, amplitude 4 mm and duration time 20 min. The main exclusion criteria for this study were: neoplasm, history of myocardial infarction, history of stroke, history of bone fracture within the two years prior to the study. To assess the effect of low frequency vibration with the parameters as specified above the following physiological and biochemical variables were used: total cholesterol serum level, high density lipoprotein (HDL) cholesterol serum level, low density lipoprotein (LDL) cholesterol serum level, triglycerides (TGD) serum level. Biochemical blood parameters were assessed before and after the trial. Friedawald’s formula was used for the assessment of LDL cholesterol serum level. Upon completion of the study and the subsequent analysis of the results obtained the following conclusions were formulated. Results: A statistically significant lowering of total serum cholesterol and LDL serum cholesterol was observed. Conclusions: The use of the vibration platform with the operational parameters specified had a beneficial effect on the variables measured.
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Sharmin, Nazia, Nasima Sultana, Pinke Mazumder, and Taniza Rahman. "Serum calcium and lipid profile in acute ischemic stroke." Bangladesh Journal of Medical Science 14, no. 3 (June 20, 2015): 286–89. http://dx.doi.org/10.3329/bjms.v14i3.23479.

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Background: Worldwide acute ischemic stroke (AIS) is a major public health problem. Therefore, this study was undertaken to see the association of some biochemical risk factors with AIS in Bangladesh. Methodology: This study was conducted in Biochemistry department of Dhaka Medical College, Dhaka from January 2014 to December 2014. In this study, 50 patients of AIS considered as case and 50 age and sex matched healthy individuals taken as control. Blood sample was collected and tested for serum calcium and lipid profile in case and control. All the parameters then compared statistically between two groups. Results: Study showed that serum calcium was significantly lower (p= 0.001) in cases and serum TChol, TAG, LDL-C significantly higher (p= 0.035, 0.001 and 0.019 respectively) and HDL-C significantly lower (0.001) in cases compared to controls. Conclusions: This study concludes that low serum calcium level and altered lipid profile are significantly associated with AIS.Bangladesh Journal of Medical Science Vol.14(3) 2015 p.286-289
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Al-Musharaf, Sara, Ghadeer S. Aljuraiban, Syed Danish Hussain, Abdullah M. Alnaami, Ponnusamy Saravanan, and Nasser Al-Daghri. "Low Serum Vitamin B12 Levels Are Associated with Adverse Lipid Profiles in Apparently Healthy Young Saudi Women." Nutrients 12, no. 8 (August 10, 2020): 2395. http://dx.doi.org/10.3390/nu12082395.

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An abnormal lipid profile is an independent risk factor for cardiovascular diseases. The relationship between vitamin B12 deficiency and lipid profile is inconclusive, with most studies conducted in unhealthy populations. In this study, we aimed to assess the relationship between serum vitamin B12 levels and lipid profiles in a cross-sectional study that included 341 apparently healthy Saudi women, aged 19–30 years, from different colleges at King Saud University, Saudi Arabia. Sociodemographic, anthropometric, biochemical, and lifestyle data were collected, including diet and physical activity. Serum vitamin B12 deficiency was defined as serum B12 level of <148 pmol/L. The prevalence of vitamin B12 deficiency was approximately 0.6%. Using multivariable linear regression models, serum vitamin B12 levels were found to be inversely associated with total cholesterol (B = −0.26; p < 0.001), low-density lipoprotein cholesterol levels (B = −0.30; p < 0.001), and triglyceride (B = −0.16; p < 0.01) after adjusting for potential confounders, while obesity indices of body mass index, central obesity, and fat percentage showed no association. Therefore, we conclude that low serum vitamin B12 levels are independently associated with abnormal lipid profiles in healthy young Saudi women. Further interventional studies are needed to determine whether improving serum vitamin B12 levels in a healthy population can improve lipid profiles.
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S. A. Hasso, R. K. Muhsen And. "Effect of age and sex on the serum biochemical profile of Local dogs." Al-Qadisiyah Journal of Veterinary Medicine Sciences 9, no. 1 (June 20, 2010): 24. http://dx.doi.org/10.29079/vol9iss1art89.

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Biochemical values of sixty clinically healthy dogs of different ages and both sexes weredetermined for the normal activities of serum aspartate aminotransferase (AST), Alanineaminotransferase (ALT), alkaline phosphatase (ALP), Urea, Creatinine, sodium, potassium,chloride, calcium, phosphorus and glucose. Comparison of the above values between males andfemales revealed that there was no statistical difference between both sexes in all biochemicalparameters. The young dogs had higher concentrations of Creatinine, ALP, and ALT while theadult dogs had higher concentrations of calcium, phosphorus, and chloride. Differences in themean value of the remaining values among young and adults were not statistically significant.
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Santos, João B. F., Maurício M. Franco, Robson C. Antunes, Ednaldo C. Guimarães, and Antonio V. Mundim. "Serum biochemical profile of Pêga breed donkeys in the state of Minas Gerais." Pesquisa Veterinária Brasileira 38, no. 6 (June 2018): 1225–31. http://dx.doi.org/10.1590/1678-5150-pvb-5121.

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ABSTRACT: For the evaluation of serum biochemical parameters of Pêga breed donkeys (Equus asinus), for the different age groups and sex, blood samples of 123 animals were analyzed, of 29 males aged from 8 days to 10 years and of 94 females (15 lactating) aged from 2 days to 12 years, from two farms in the central-southern Minas Gerais, Brazil. The donkeys were divided by age into 5 groups: Group 1 (≤6 months), Group 2 (7-12 months), Group 3 (13-48 months), Group 4 (49-72 months), and Group 5 (≥73 months). According to the sex, they were divided into two groups, males and females. Serum biochemical elements: total protein, albumin, globulin, the A:G ratio, cholesterol, triglycerides, uric acid, creatinine, urea, phosphorus, calcium, Ca:P ratio, magnesium, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma glutamyl transferase (GGT) and creatine kinase (CK), were evaluated in all animals. No significant differences were found for globulins, uric acid, urea and A:G ratio between age groups. Group 4 showed the highest values for total protein when compared with animals in Group 1 and 2. In Goup 2, the donkeys showed albumin levels lower than Group 3 and 4. Group 1 they had cholesterol levels higher than those in Group 2 and 4, and similar of the other groups. Higher phosphorus serum concentration was observed in Group 1. Calcium was significantly lower in Group 2. The Ca:P ratio was higher for Group 5. The magnesium values were significantly higher in donkeys older than 49 months (Group 4 and 5). The value of AST was lower for group 1. The ALP enzyme was significantly higher in younger animals up to 12 months, followed by gradual decrease with advancing age. The values of GGT were higher in donkeys up to 6 months, followed by decreasing values for subsequent groups. No differences were found between genders for albumin, cholesterol, creatinine, urea, uric acid, Ca:P ratio, magnesium, ALT, AST, and alkaline phosphatase. Females had higher values for total protein, globulin and triglycerides. Males showed higher values for A:G ratio, phosphorus, calcium and CK. The results showed that age and sex can influence serum biochemical values of Pêga breed donkeys.
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Padmavathi, Pannuru, Vaddi Damodara Reddy, and Nallanchakravarthula Varadacharyulu. "Influence of Chronic Cigarette Smoking on Serum Biochemical Profile in Male Human Volunteers." JOURNAL OF HEALTH SCIENCE 55, no. 2 (2009): 265–70. http://dx.doi.org/10.1248/jhs.55.265.

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41

van de Kerkhof, N., D. Fekkes, F. van der Heijden, and W. M. A. Verhoeven. "Neurotrophic proteins and symptom profile in psychotic disorders." European Psychiatry 26, S2 (March 2011): 1523. http://dx.doi.org/10.1016/s0924-9338(11)73227-8.

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BackgroundPsychotic disorders are highly prevalent and are treated with antipsychotics. There are no biological markers to predict or measure treatment effects. Research to neurotrophic proteins Brain Derived Neurotrophic Factor (BDNF) and S100B demonstrated association with psychotic symptoms and suggested association with treatment outcome and symptomatology.ObjectivesInvestigate the relevance of neurotrophic proteins BDNF and S100B in patients with psychotic disorders treated with antipsychotics.AimsPrimary objective is to investigate the relationship between serum levels of BDNF and S100B and symptomatology at baseline and after six weeks of treatment. Furthermore, a detailed evaluation of symptom profile and treatment effect is performed.Methods80 patients with acute and chronic psychotic disorder were evaluated during six weeks while receiving antipsychotic treatment of any kind. Symptomatology was assessed using CASH, PANSS and CGI-S/I. Biochemical parameters were determined at baseline and after six weeks. Symptomatology and treatment effect were related to biochemical results.ResultsPreliminary analyses show an overall treatment response of 19% (reduction of PANSS). A significant difference was found at baseline between patients with first-episode psychosis and patients with relapse or chronic psychosis (BDNF 12,4 vs. 21,7μg/l P ≤ 0,01, S100B 0,1055 vs. 0,05937 μg/l, P < 0,05). During treatment, serum levels of neurotrophic proteins returned to normal values in both groups.ConclusionsSix weeks of antipsychotic treatment results in a modest symptomatic improvement. In subgroups with first episode psychosis, S100B levels are higher and BDNF levels are lower. The normalization of both serum levels suggests an effect of antipsychotic treatment on brain neurochemical processes.
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42

Richardson, EF, and NO Brown. "Hematological and biochemical changes and results of aerobic bacteriological culturing in dogs undergoing splenectomy." Journal of the American Animal Hospital Association 32, no. 3 (May 1, 1996): 199–210. http://dx.doi.org/10.5326/15473317-32-3-199.

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Changes in complete blood count (CBC), bone marrow, reticulocyte count, coagulation profile, biochemical analysis, and serum iron, transferrin, and immunoglobulin M (IgM) concentrations were measured three and 10 days after splenectomy in 12 dogs. Spleens were cultured aerobically for bacteria and submitted for histopathological evaluation in 23 dogs undergoing splenectomy. There were no consistent changes in red blood cell (RBC), white blood cell (WBC), or platelet counts; bone-marrow samples; or biochemical profiles. Serum iron, transferrin, and IgM concentrations remained normal. Eight (35%) bacterial cultures yielded growth. Five of the 23 dogs had pyrexic episodes two-to-five days after surgery. In contrast to previous reports done on healthy dogs, this study shows that dogs with splenic disease have no characteristic changes in hematological or biochemical parameters after splenectomy. Rather, the changes tended to reflect the primary disease process. Splenic vascular compromise or a decrease in processing of bacteria may have resulted in the bacterial growth. There was no direct correlation to pyrexic postoperative episodes.
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43

Hassan, Mohammed Zuheir, Mohammed Jaffer AL Anssari, Hayder Hasan Rajab, Ali Abbas Abo Ajon, Ashraf Raoof Mohammed Ali, and Hussein Raof Al Ghazali. "Study of Walnut Oil Supplementation on Serum Biochemical Parameters and Histopathology of Male Rats." NeuroQuantology 19, no. 6 (July 14, 2021): 08–14. http://dx.doi.org/10.14704/nq.2021.19.6.nq21060.

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The purpose of the experiment is an investigate the association of walnut oil with lipid profiles, glucose as well as total proteins and assessment its side effect on some sensitive organs such as the liver and spleen tissues. The experiment divided into two main groups are treated group with walnut oil and the control group, where the former divided into two subgroups 0.25 and 0.5 ml of oil per each. We found a statistically non-significant difference between treated and control groups (for total protein, lipid profile, and glucose). There was no change in total protein, but cholesterol decreased by 0.25 ml but a little increased by 0.5 ml. HDL was increased for the treated group. While on 0.25 ml LDL decreased in treated animals, on another hand no change for 0.5 ml. Also, no change for VLDL between treated and control. The only triglyceride was increased but non-significant for the treated group compared with the control. Both doses decreased in treated animals for glucose. We also found an increase in whole-body weight and on sensitive organs such as the liver and spleen. Even no change in a histological study for the mentioned organs. The conclusion: By walnut oil, all parameters have changed despite the treated group was normal without any induced diseases. So, recommended the researchers induce the disorders in the liver and assessment the extracted oil on the lipid profile.
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44

Millam, Jacob, S. S. Bello, H. Y. Abbaya, and P. A. John. "GROWTH PERFORMANCE AND SERUM BIOCHEMICAL PROFILE IN YANKASA RAMS FED ALKALI-TREATED GROUNDNUT SHELLS." FUDMA JOURNAL OF SCIENCES 4, no. 3 (September 11, 2020): 52–59. http://dx.doi.org/10.33003/fjs-2020-0403-251.

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The study was conducted to assess the chemical composition of alkali treated groundnut shells and their effects on growth and serum biochemical parameters in Yankasa rams. A total of 4 Yankasa rams where used to conduct the experiment in a 4×4 Latin square design. Four diets (14% crude protein) were formulated to contain untreated groundnut shell (UTGNS), urea treated groundnut shell (UGNS), lime treated groundnut shell (LGNS) and urea-lime treated groundnut shell (ULGNS). Growth and blood serum parameters were measured at the end of each period. Samples of the treated groundnut shell and the experimental diets were analysed for proximate analysis, neutral detergent fibre, acid detergent fibre and lignin. The results of the chemical composition of treated groundnut shell showed that alkali chemical increased the protein, energy, and reduced the cell wall constituents of the untreated groundnut shell. Significant (P<0.05) effect were observed for daily weight gain, daily feed intake and feed conversion ratio and serum biochemical profile. Daily feed intake and daily weight gain were higher in UTGNS (183.50 g and 1110.90 g respectively); UGNS had the least feed conversion ratio (5.98). Total protein and glucose levels were above normal range of serum biochemical values for sheep while blood urea and creatinine were within normal range of values. The study revealed that dietary inclusion of treated groundnut shell did not show any negative effect on the growth performance and kidney function but indicated some signs of ailment on the activities of the liver and pancreas.
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45

Stevanovic, O., M. Stojiljkovic, D. Nedic, D. Radoja, V. Nikolic, R. Prodanovic, S. Ivanov, and I. Vujanac. "Variability of blood serum biochemical parameters in Karakachan sheep." Biotehnologija u stocarstvu 31, no. 1 (2015): 55–62. http://dx.doi.org/10.2298/bah1501055s.

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Karakachan sheep represents an endangered, indigenous sheep breed from Balkan Peninsula. There is relatively little information about the characteristics of this sheep breed in the veterinary scientific literature. The aim of this research was an examination of certain metabolic profile parameters of the Karakachan sheep blood serum, and variability of their concentrations in comparison to age and some other indigenous sheep breeds from Balkans. Examination was conducted on 14 clinically healthy sheep divided in two age groups. Blood samples were collected by puncture of v. jugularis and blood serum was separated after spontaneous coagulation. The concentrations of total protein, albumin, calcium, inorganic phosphorus, aspartate amino transferase (AST) and ?- glutamyl transferase (GGT) were determined. In relation to age of Karakachan sheep, statistically significant difference between the calculated mean values of examined parameters was not observed. A statistically significant difference was found between the mean concentrations of the studied parameters in Karakachan sheep and other breeds in total protein (Tsigai, Dubrovnik and Dalmatian sheep), albumin (Dalmatian), calcium and inorganic phosphorus (Tsigai, Dubrovnik) and AST's (Dalmatian, Karakachan sheep from Bulgaria).
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46

Rodrigues, Gustavo Moya, Fernanda Gatti de Oliveira Nascimento, Amanda Bizare, Wilson Junior Oliveira, Ednaldo Carvalho Guimarães, and Antonio Vicente Mundim. "Serum Biochemical Profile of Nile Tilapias (Oreochromis niloticus) Bred in Net Cages during Summer and Winter." Acta Scientiae Veterinariae 46, no. 1 (May 16, 2018): 8. http://dx.doi.org/10.22456/1679-9216.81814.

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Background: The growth of fish farming in Brazil has been noticeable over the past few years, and the Nile tilapia (Oreochromis niloticus) is the most bred species in the country. Studies on the physiology of these animals are necessary so that the production continues to grow and to improve its rates. However, very discrepant data are still found in the area of blood biochemistry. The aim of this study was to evaluate the physiological variations in serum concentrations of proteins, metabolites, electrolytes and serum enzymes in Nile tilapias bred in net cages in Cachoeira Dourada, state of Minas Gerais, Brazil, during summer and winter.Materials, Methods & Results: During the year of 2016, samples from 100 Nile tilapias were collected during summer (January and February) and samples from 100 Nile tilapias were also collected during winter (July and August). Only one blood sample was collected by caudal venipuncture of each fish, just before the slaughter, always in the morning. The serum samples obtained were then analyzed for serum concentrations of proteins, metabolites, electrolytes, lipids and serum enzymes. Serum concentrations of total proteins, globulins, triglycerides, high density lipoprotein (HDL), alkaline phosphatase, sodium and chloride were significantly higher during winter in comparison to summer, while the serum concentration of uric acid was significantly lower during winter in comparison to summer.Discussion: Due to the lower temperature of water during winter, tilapias reduced food intake and became more susceptible to diseases, which led to an increase in circulating globulins. In that same season, there was an increase in serum concentrations of sodium and chloride as a result of adding sodium chloride to the water in order to stimulate mucus secretion on the fishes’ skin and gills to prevent pathologies. Triglycerides, HDL, and uric acid are considered indicators of nutritional status of animals. The increase in serum concentrations of triglycerides and HDL indicates that tilapias are mobilizing energy reserves, however, when the increase in serum concentrations of uric acid is observed, it is fair to assume there has been an increase in food intake, raising protein catabolism. The increase of serum concentration in alkaline phosphatase is caused by the presence of multiple forms of enzymes that are induced by the action of endogenous corticosteroids, which are produced as a result of the stress suffered by tilapias during the fishing process and during winter, when the water temperature is lower than the ideal for this species. It can be concluded that the season has influence on some serum biochemical constituents of Nile tilapias bred in net cages, and that the predominant variations happen during winter due to immunity decline and during summer due to the increase in food intake and, consequently, in the metabolism of tilapias.
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47

Silva, LFN, CCM Riani-Costa, PRR Ramos, and RK Takahira. "Seasonal influence on biochemical profile and serum protein electrophoresis for Boa constrictor amarali in captivity." Brazilian Journal of Biology 71, no. 2 (May 2011): 517–20. http://dx.doi.org/10.1590/s1519-69842011000300023.

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Similarly to other reptiles, snakes are ectothermic animals and depend exclusively on the environment for the maintenance of their physiological, biochemical and immunological processes. Thus, changes in biochemical values can be expected due to seasonal influence. Twenty-two adult specimens of Boa constrictor amarali kept in captivity were used. Blood collections were done in two different seasons: winter (July 2004) and summer (January 2005) for the following assays: uric acid, aspartate aminotransferase (AST), glucose, cholesterol, total protein, and serum protein electrophoresis. The mean biochemical results found in summer and winter, respectively, were: 6.3 ± 3.4 and 11.3 ± 6.2 mg/dL for uric acid; 28.7 ± 12.4 and 20.7 ± 16.2 UI/L for AST; 26.3 ± 17 and 17.4 ± 6.8 mg/dL for glucose; 67.3 ± 30.2 and 69.7 ± 38.5 mg/dL for cholesterol; and 5.9 ± 1.6 and 5.9 ± 1.4 g/dL for total protein. Results regarding electrophoresis in summer and winter, respectively, were: 1.9 ± 0.7 and 2.4 ± 0.6 g/dL for albumin; 0.7 ± 0.2 and 0.5 ± 0.2 g/dL for α-globulin; 1.5 ± 0.5 and 1.7 ± 0.6 g/dL for β-globulin; and 1.8 ± 0.5 and 1.5 ± 0.5 g/dL for g-globulin. In the summer, there was a significant increase in AST and a decrease in uric acid (p < 0.05). Serum protein electrophoresis showed a significant increase in α-globulin fraction (p < 0.05) in the same season. There were not significant differences between seasons for the remaining variables. Based on these results, the period of the year must be considered in the interpretation of some biochemical values for these animals.
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48

Codreanu, Mario Darius. "Correlations Between Changes in Serum Cortisol Level and Biochemical Liver Profile and Adrenal Ultrasound Appearance in Hyperadrenocorticism (Cushing's Syndrome) in Dogs." Indian Journal of Applied Research 4, no. 5 (October 1, 2011): 455–57. http://dx.doi.org/10.15373/2249555x/may2014/140.

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49

Miah, Md Helal, Md Zakir Hossain, Bidhu Bhusun Das, Md Mokhlesur Rahman Sarker, Sumanta Kumar Saha, Md Ashraful Haque, and Md Ghulam Yusuf. "Serum Iron Profile in Chronic Renal Failure Patients." Ibrahim Cardiac Medical Journal 2, no. 2 (November 11, 2012): 8–13. http://dx.doi.org/10.3329/icmj.v2i2.52849.

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Background & objective: Chronic Renal Failure (CRF) is a serious condition with a worldwide impact. Anemia is a common complication of CRF leading to significant morbidity. Iron deficiency may be a contributing factor for developing anemia in CRF patients. It may be particularly problematic during erythropoietin therapy. This study was intended to find the serum iron status in CRF patients. Method: This cross sectional study was conducted on 100 consecutive patients of CRF in the Department of Medicine, Rangpur Medical College & Hospital, Rangpur and Hypertension & Research Centre, Rangpur between July 2010 to June 2012. Result: 40% of the patients were 40-59 years old, 28% were 20 - 39 years and 32% >60 years old. Males were predominant (64%) than the females (36%). None of the biochemical variables (serum creatinine, haemoglobin and serum iron profile), except total iron binding capacity (TIBC) differ by sex. TIBC was significantly higher in females than that males (p = 0.029). Of the 100 patients 40% were iron deficient; of them 12(30%) had absolute iron deficiency and 28(70%) relative iron deficiency. Iron deficiency was not influenced by sex (p = 0.519). It was not even affected by the degree of renal insufficiency (p = 0.524). However, the incidence of severe anemia increases significantly with the degree of renal insufficiency (p = 0.037). Conclusion: Serum iron profile remains normal in most of the cases of CRF patients. It should be investigated in every CRF patients before deciding for iron therapy. Ibrahim Cardiac Med J 2012; 2(2): 8-13
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50

Srinivas V, Balasankar R, Prathyusha K, Manisha Patel K, Sharvana bhava B S, and Venkateshwarlu E. "Assessment of serum biochemical proϑile in breast cancer patients." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (December 25, 2020): 7775–81. http://dx.doi.org/10.26452/ijrps.v11i4.4373.

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Cancer occurrence and it's connected mortality on the rise and has become a significant general wellbeing concern. As of now, it is the subsequent driving reason for death around the globe. Bosom malignant growth is the world's most basic malignant growth in ladies with high mortality rate. This study was planned to evaluate the ailment movement and metastasis. The current investigation is a close, observational examination. One hundred seven female bosom disease patients over the age of 35 years were enlisted to examine varieties in serum biochemical profile of bosom malignant growth patients. In this investigation, the mean estimations of Blood urea nitrogen, Uric corrosive, White platelets and Neutrophil lymphocyte proportion were discovered to be diminished, and that of Serum creatinine, Serum glutamic oxaloacetic transaminase, serum glutamic pyruvic transaminase, Alkaline phosphatase, Fasting glucose, neutrophils and lymphocytes were discovered to be expanded from first to fourth patterns of chemotherapy. The obtained parameters were expressed as Mean ± SD, and the parameters were compared by using paired t-test. All Biochemical parameters should be monitored after every chemotherapy cycle until the completion of a planned treatment regimen. The changes in biochemical parameters provide an opportunity to explain the degree of risk in breast cancer patients by metastasis which helps to avoid further worsening of the disease.
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