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Journal articles on the topic 'Serum Efficacy'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Linder, Stig, and Ayodele Alaiya. "Serum efficacy biomarkers for oncology." Biomarkers in Medicine 3, no. 1 (2009): 47–54. http://dx.doi.org/10.2217/17520363.3.1.47.

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Haberman, R. J., P. W. Ladenson, L. S. Cameron Griffith, and E. P. Veltri. "Serum reverse T3and amiodarone efficacy." Clinical Cardiology 12, no. 3 (1989): 140–44. http://dx.doi.org/10.1002/clc.4960120305.

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WALSH, NANCY. "Serum Markers Reflect Cyclophosphamide Efficacy." Rheumatology News 6, no. 9 (2007): 7. https://doi.org/10.1016/s1541-9800(07)70507-0.

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Krishna, Singh, Vaish Rahul, and Kumar Gupta Ashwani. "Comparative Study of Efficacy and Safety of Ramipril and Telmisartan on Serum Electrolytes in Newly Diagnosed Hypertensive Patients." International Journal of Pharmaceutical and Clinical Research 16, no. 5 (2024): 171–77. https://doi.org/10.5281/zenodo.11399590.

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<strong>Introduction:</strong> ACEIs (angiotensin converting enzyme inhibitor) and ARBs (angiotensin II receptor blockers) are two medications that are frequently recommended to treat heart conditions and hypertension. It is now crucial to assess and investigate into how these medications affect the variations in serum electrolytes. <strong>Objective:</strong>  To compare the effects of Ramipril and Telmisartan on blood pressure, serum potassium and serum sodium. <strong>Materials and Methods:</strong> The prospective study, which lasted 24 weeks and involved patients

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Sanjana, Deshmukh* Dr. Nikita Parage. "A Comprehensive Review on Face Serum." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4229–46. https://doi.org/10.5281/zenodo.15512543.

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Currently, there is a significant rise in the demand for skin care products and treatments. Many individuals are increasingly preoccupied with enhancing their appearance. Consequently, a variety of products have been launched to promote a youthful and attractive look. The use of herbal ingredients in cosmetics has gained global popularity. The market for herbal cosmetics is expanding, as they are considered an invaluable gift from nature. The formulation of these products involves combining various herbal components with a cosmetic base to nourish and address different skin concerns. As a resu

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&NA;. "Serum vancomycin concentrations predict efficacy and nephrotoxicity." Inpharma Weekly &NA;, no. 974 (1995): 17. http://dx.doi.org/10.2165/00128413-199509740-00034.

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Wen, Sihui, Shenghao Cheng, Shaobing Xie, et al. "Predictive Value of Nasal Nitric Oxide and Serum NOS2 Levels in the Efficacy of Subcutaneous Immunotherapy in Pediatric Patients with Allergic Rhinitis." Mediators of Inflammation 2022 (August 16, 2022): 1–10. http://dx.doi.org/10.1155/2022/1679536.

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Background. Subcutaneous immunotherapy (SCIT) is an effective therapy for allergic rhinitis (AR), but some AR patients still do not benefit from it. Nasal nitric oxide (nNO) and inducible nitric oxide synthase (iNOS/NOS2) act important roles in AR. This study aims to explore the abilities of serum NOS2 and nNO in predicting the clinical efficacy of SCIT in AR patients. Methods. We recruited 40 healthy controls (HCs) and 120 AR patients in this study. Serum NOS2 and nNO levels were compared between the two groups. In the AR group, patients underwent and finished 1-year of SCIT, and divided into

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Payal, Jagnade* Shrutika Nakshane Gaurav Meshram Dr. Nilesh Chachda. "A Comparative Review of Sunscreen Serum: UV Protection Efficacy and Spectroscopic Analysis." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 2097–105. https://doi.org/10.5281/zenodo.14474645.

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This review examines the efficacy and formulation of sunscreen serums, emphasizing their UV protective properties evaluated through UV spectroscopy. By delving into various ingredients and their absorption spectra, the study highlights the ultimate importance of understanding how different formulations influence UV protection. Additionally, the article addresses challenges in standardization and the need for rigorous testing to ensure consumer safety and product effectiveness. The findings underscore the role of UV spectroscopy as a vital tool in the assessment and development of advanced suns

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Soleimani, Neda, Sahand Mohammadzadeh, and Fateme Asadian. "Lipemia Interferences in Biochemical Tests, Investigating the Efficacy of Different Removal Methods in comparison with Ultracentrifugation as the Gold Standard." Journal of Analytical Methods in Chemistry 2020 (February 12, 2020): 1–6. http://dx.doi.org/10.1155/2020/9857636.

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Introduction. As a common interferer in clinical chemistry, lipemic specimens could be a source of significant analytical errors. Ultracentrifugation has been by far the only reliable, but an unavailable and expensive, method to eliminate the lipemic effect. Materials and Methods. Among the daily samples, those with triglyceride >400 mg/dL (4.6 mmol/L) and also turbid were selected, divided into three groups, based on triglyceride concentration, and three pooled serums were made for each group. Then all pooled serums were investigated by using a DIRUI biochemistry analyzer CS-800 for routin

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Garg, Abhimanyu. "Efficacy of dietary fiber in lowering serum cholesterol." American Journal of Medicine 97, no. 6 (1994): 501–3. http://dx.doi.org/10.1016/0002-9343(94)90343-3.

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Saxena, Ashima, Wei Sun, Paul A. Dabisch, et al. "Efficacy of human serum butyrylcholinesterase against sarin vapor." Chemico-Biological Interactions 175, no. 1-3 (2008): 267–72. http://dx.doi.org/10.1016/j.cbi.2008.05.022.

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Latran, Michael J. "Review of Serum Voriconazole Concentrations and Correlations with Adverse Events and Efficacy." Journal of Pharmacy Technology 25, no. 3 (2009): 183–89. http://dx.doi.org/10.1177/875512250902500307.

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Objective: To review the available evidence regarding the monitoring of serum voriconazole concentrations in terms of efficacy and safety. Data Sources: A literature search of MEDLINE was conducted (1950–February 2009), with combinations of the following search terms: voriconazole, therapeutic drug monitoring, voriconazole serum concentrations, voriconazole levels, trough, and adverse events. Data Collection: All studies and case reports that evaluated serum voriconazole concentrations in adults were reviewed and considered for inclusion. Citations in identified articles were searched for addi

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Deng, Peng, Mi Li, and Yuni Wu. "The Predictive Efficacy of Serum Exosomal microRNA-122 and microRNA-148a for Hepatocellular Carcinoma Based on Smart Healthcare." Journal of Healthcare Engineering 2022 (January 4, 2022): 1–10. http://dx.doi.org/10.1155/2022/5914541.

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Objective. Hepatocellular carcinoma (HCC) remains a devastating tumor globally. Serum exosomes are reliable biomarkers for tumors, including HCC. Hence, this study explored the efficacy and mechanism of serum exosomes in HCC. Methods. microRNA (miR)-122 and miR-148a expressions in serum exosomes from HCC patients and healthy subjects and their predictive efficacy for HCC were detected. Correlation between serum exosomal miR-122/148a expressions with survival rate, clinical stage, lymph node metastasis, and tumor differentiation level and levels of HCC-related serum markers (CA199, FucAFP, ALD-

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Kwon, Eun-Jeong, Yunyeong Choi, Shin Young Kim, et al. "Development of Drug Efficacy Testing Platform for Glomerulonephritis." Micromachines 15, no. 3 (2024): 317. http://dx.doi.org/10.3390/mi15030317.

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We developed a 3D glomeruli tissue chip for glomerulonephritis (GN) testing, featuring a gravity-driven glomerular filtration barrier (GFB) with human podocytes and endothelial cells with a bidirectional flow in the bottom channel. Using puromycin-induced GN, we observed decreased cell viability, increased albumin permeability, and reduced WT1 and nephrin compared to the normal GFB. Tacrolimus restored cell viability, reduced albumin permeability, and increased WT1 expression. Using serum from five membranous nephropathy (MN) patients, we created MN models using a GFB-mimicking chip. A notable

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Liu, Wenlong, Qingxiang Zeng, and Renzhong Luo. "Predictors for Short-Term Efficacy of Allergen-Specific Sublingual Immunotherapy in Children with Allergic Rhinitis." Mediators of Inflammation 2020 (April 21, 2020): 1–7. http://dx.doi.org/10.1155/2020/1847061.

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Background.A good compliance in allergen-specific sublingual immunotherapy (SLIT) often comes from good short-term efficacy. We aimed to evaluate the pretreatment parameters which can predict the short-term clinical efficacy in children that underwent SLIT. Methods. 517 children with allergic rhinitis (AR) that underwent SLIT were recruited in this study. Baseline clinical characteristics and laboratory parameters were collected, and the clinical efficacy was evaluated using symptom and medication scores. A multivariate logistic regression model and receiver operating characteristic (ROC) curv

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Bezek, Štefan, Zuzana Brnoliaková, Ružena Sotníková, et al. "Monotherapy of experimental metabolic syndrome: I. Efficacy and safety." Interdisciplinary Toxicology 10, no. 3 (2017): 81–85. http://dx.doi.org/10.1515/intox-2017-0013.

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AbstractElevated plasma cholesterol, especially low density lipoprotein (LDL) cholesterol, is one of the major risk factors for atherosclerosis and coronary heart disease. Hereditary hypertriglyceridemic rats (hHTG) were developed as a new inbred model for the study of relationships between blood pressure and metabolic abnormalities. The aim of this work was to determine the cholesterol-lowering and antioxidant effects of the novel pyridoindol derivative SMe1EC2, compared to the cholesterol-lowering drug atorvastatin, in rats fed either standard or high-fat and high-cholesterol diet (HFC; 1% c

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Lokesh, N. Patil, and P. Deshmukh Swati. "Apple serum for health and beauty." GSC Biological and Pharmaceutical Sciences 25, no. 2 (2023): 180–86. https://doi.org/10.5281/zenodo.10609209.

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In recent years, there has been a growing interest in harnessing the potential of natural ingredients for enhancing health and beauty. Apple serum, derived from apples, has gained prominence as a potent elixir with numerous benefits for both internal well-being and external appearance. This abstract provides an overview of the research and findings related to the application of apple serum in health and beauty. The primary components of apple serum include antioxidants, vitamins, and minerals that play a pivotal role in skin health, hair vitality, and overall bodily health. Apple serum is abun

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Dai, Shan, Nan Dai, and Jie Zhang. "Nanomagnetic bead-based nucleic acid isolation to examine the correlation of serum TRAP1 and MDSC levels with clinical treatment efficacy and prognosis in nonsmall cell lung cancer." Materials Express 13, no. 9 (2023): 1483–89. http://dx.doi.org/10.1166/mex.2023.2501.

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To explore the correlation of tumor necrosis factor receptor-associated protein (TRAP1) and myeloid-derived suppressor cells (MDSCs) in peripheral blood with clinical treatment efficacy and prognosis in nonsmall-cell lung cancer (NSCLC). The study cohort comprised 112 patients with NSCLC who were treated between March 2020 to December 2022, including 45 and 67 patients with stage I–II and III–VI NSCLC, respectively, and 90 healthy individuals as controls. Peripheral blood samples of study participants before and after chemotherapy were collected. Serum MDSC and TRAP1 levels were compared in pa

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Aguilar, Adriana, Jacques Planas, Enrique Trilla, and Juan Morote. "Methods for Evaluating the Efficacy of Medical Castration: A Systematic Review." Cancers 15, no. 13 (2023): 3479. http://dx.doi.org/10.3390/cancers15133479.

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Measuring serum testosterone determination during medical castration is recommended by prostate cancer (PCa) guidelines to assess its efficacy and define castration resistance. It has been suggested that other biochemical compounds, such as free testosterone or luteinising hormone (LH), could also assess castration efficacy. We aimed to analyse the current evidence for serum biochemical compounds that could be appropriate candidates for evaluating medical castration efficacy. A systematic review was conducted after two investigators independently searched the literature in the PubMed, Cochrane

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., Naseemullah, Abdul Qayum Khan, Farooq Azam Khan, Shahzad Rashid Awan, and Mehran Khan. "Efficacy of Intramuscular Platelet Rich Plasma Versus Oral Antihistamine In Chronic Urticaria." Pakistan Journal of Medical & Health Sciences 16, no. 10 (2022): 390–92. http://dx.doi.org/10.53350/pjmhs221610390.

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Background: Chronic urticaria is defined as a pruritic skin disorder that persists daily or about daily for ˃6 weeks. Chronic urticaria is a common problem in Pakistan. The common treatment method is oral histamine. Currently the important treatment method used is autologous serum therapy. The objective of this study was to determine the efficacy of intramuscular platelet rich plasma versus oral antihistamine in the treatment of chronic urticaria Methodology: This study was randomized controlled clinical trial carried out at the Dermatology Department, Qazi Hussain Ahmad Complex Nowshera and a

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Draelos, Zoe Diana. "25877 Efficacy evaluation of a topical hyaluronic acid serum." Journal of the American Academy of Dermatology 85, no. 3 (2021): AB73. http://dx.doi.org/10.1016/j.jaad.2021.06.317.

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INAGAKI, Y., K. SUMIKAWA, K. FUKUMITSU, K. YOSHIKAWA, and I. YOSHIYA. "A323 SERUM CONCENTRATIONS OF MIDAZOLAM AND THE ANESTHETIC EFFICACY." Anesthesiology 73, no. 3A (1990): NA. http://dx.doi.org/10.1097/00000542-199009001-00319.

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Sabatini, Luca, Claire Wilson, Talha Al Shawaf, Adrian Lower, and Jurgis G. Grudzinskas. "Efficacy of serum albumin to prevent ovarian hyperstimulation syndrome?" Fertility and Sterility 67, no. 3 (1997): 587–88. http://dx.doi.org/10.1016/s0015-0282(97)80098-2.

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Yumoto, Yu, Takehiko Yukishita, Keiko Lee, and Hiroyuki Kobayashi. "The efficacy of recovery care with cool veil serum." Health 02, no. 12 (2010): 1425–29. http://dx.doi.org/10.4236/health.2010.212212.

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Pearl, Karlyn K., Ana A. Ortiz, and William Pearl. "Efficacy of Immunization with a Combination of Serum and Recombinant Hepatitis B Vaccines." Infection Control & Hospital Epidemiology 14, no. 8 (1993): 476–78. http://dx.doi.org/10.1086/646783.

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AbstractObjective:To evaluate the efficacy of giving a third dose of recombinant hepatitis B vaccine to healthcare workers who already had received two doses of serum-derived vaccine, which is no longer available in the United States.Design:Volunteers who already had received two standard doses of serum-derived vaccine were given a third dose of either serum or recombinant vaccine in a double-blind fashion. Antibodies to hepatitis B surface antigen were measured at the time of the third immunization, three months later, and one year after the third immunization.Setting:U.S. Army Medical Center

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Alnafisah, Ruyuf Y., Atheer S. Alragea, Mona K. Alzamil, and Amani S. Alqahtani. "The Impact and Efficacy of Vitamin D Fortification." Nutrients 16, no. 24 (2024): 4322. https://doi.org/10.3390/nu16244322.

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Vitamin D deficiency is a global health issue linked to various chronic diseases and overall mortality. It primarily arises from insufficient sunlight exposure, compounded by dietary limitations. Vitamin D fortification of commonly consumed foods has emerged as a viable public health intervention to address this deficiency. This review evaluates the impact of vitamin D food fortification on serum levels, intake, and health outcomes and explores the stability, bio-accessibility, bioavailability, and cost-effectiveness of such interventions. A comprehensive literature search was conducted in Pub

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Fröscher, Walter, Ferdinand Keller, Heinrich Vogt, and Günter Krämer. "Prospective study on concentration‐efficacy and concentration‐toxicity: Correlations with lamotrigine serum levels." Epileptic Disorders 4, no. 1 (2002): 49–55. http://dx.doi.org/10.1684/j.1950-6945.2002.tb00436.x.

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ABSTRACT Rationale: The relationship between lamotrigine (LTG) serum concentration and clinical response in patients with epilepsy is still controversial. We therefore performed a prospective study in which LTG was added to the existing therapeutic regimen in patients with poorly controlled epilepsy. The goal of the study was to determine the serum levels of patients with seizure reduction of at least 50% after addition of LTG, and to assess a possible relationship between the occurrence of adverse effects due to LTG and its serum concentration. Methods: Fifteen adult patients were evaluated w

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Ahmad, Saeed, Ejaz Mohiuddin, Syed Muhammad Ali Shah, et al. "Therapeutic Efficacy of Urinile Against Gouty Arthritis." Dose-Response 18, no. 4 (2020): 155932582094693. http://dx.doi.org/10.1177/1559325820946934.

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Gout is arthritis caused due to Monosodium urate (MSU) crystals deposition occurring particularly in patients with associated comorbidities limiting the use of conventional therapies. This study was planned to evaluate the therapeutic efficacy of urinile (a herbal drug) for the treatment of gouty arthritis. Allopurinol was used as standard drug (positive control). The study population of 250 volunteers (gouty arthritis patients) were divided into 2 groups as test and control group (n = 125 each). Gouty arthritis patients in test and control group were treated with 300 mg each of urinile and al

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Sommatis, Sabrina, Maria Chiara Capillo, Cristina Maccario, et al. "Biophysical and Biological Tools to Better Characterize the Stability, Safety and Efficacy of a Cosmeceutical for Acne-Prone Skin." Molecules 27, no. 4 (2022): 1255. http://dx.doi.org/10.3390/molecules27041255.

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(1) Background: Acne is a widespread skin disease, especially among adolescents. Following the COVID-19 pandemic and the use of masks, the problem has been affecting a greater number of people, and the attention of the skin care beauty routine cosmetics has been focused on the “Maskne”, caused by the sebum excretion rate (SER) that stimulates microbial proliferation. (2) Methods: the present study was focused on the rheological characterization and quality assurance of the preservative system of an anti-acne serum. The biological effectiveness (cytotoxicity—skin and eye irritation—antimicrobia

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Abou-Khalil, Bassel W. "Making Sense of Lamotrigine Serum Levels." Epilepsy Currents 5, no. 3 (2005): 115. http://dx.doi.org/10.1111/j.1535-7511.2005.05303.x.

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Correlating Lamotrigine Serum Concentrations with Tolerability in Patients with Epilepsy Hirsch LJ, Weintraub D, Du Y, Buchsbaum R, Spencer HT, Hager M, Straka T, Bazil CW, Adams DJ, Resor SR Jr, Morrell MJ Neurology 2004;63:1022–1026 Objective To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy. Methods The charts of 811 outpatients with epilepsy who had received LTG and were seen at the Columbia Comprehensive Epilepsy Center after January 1, 2000, were reviewed. Data gathered included levels, dosage, duration of use, concomitant antiepilep

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Mejías-Trueba, Marta, Marta Alonso-Moreno, Laura Herrera-Hidalgo, and Maria Victoria Gil-Navarro. "Target Attainment and Clinical Efficacy for Vancomycin in Neonates: Systematic Review." Antibiotics 10, no. 4 (2021): 347. http://dx.doi.org/10.3390/antibiotics10040347.

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Vancomycin is commonly used as a treatment for neonatal infections. However, there is a lack of consensus establishing the optimal vancomycin therapeutic regimen and defining the most appropriate PK/PD parameter correlated with the efficacy. A recent guideline recommends AUC–guided therapeutic dosing in treating serious infections in neonates. However, in clinical practice, trough serum concentrations are commonly used as a surrogate PKPD index for AUC24. Despite this, target serum concentrations in a neonatal population remain poorly defined. The objective is to describe the relationship betw

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Perreault, Marc M., Nikola J. Ostrop, and Michael G. Tierney. "Efficacy and Safety of Intravenous Phosphate Replacement in Critically Ill Patients." Annals of Pharmacotherapy 31, no. 6 (1997): 683–88. http://dx.doi.org/10.1177/106002809703100603.

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OBJECTIVE: To evaluate the efficacy and safety of intravenous potassium phosphate administered in a fixed-dose regimen in critically ill patients. DESIGN: Prospective, unblind study. SETTING: Surgical—medical intensive care unit (ICU). PARTICIPANTS: Patients who developed hypophosphatemia during their ICU admission. INTERVENTIONS: Patients with a serum phosphate concentration between 1.27 and 2.48 mg/dL (group 1) and those with a concentration of 1.24 mg/dL or less (group 2) received 15 and 30 mmol, respectively, of phosphate as a potassium salt via a central line over 3 hours. MAIN OUTCOME ME

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Zhou, Yandan, Min Xu, Wei Gong, et al. "Circulating MMP-12 as Potential Biomarker in Evaluating Disease Severity and Efficacy of Sublingual Immunotherapy in Allergic Rhinitis." Mediators of Inflammation 2022 (June 12, 2022): 1–10. http://dx.doi.org/10.1155/2022/3378035.

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Background. Allergic rhinitis (AR) is a highly heterogeneous disease, and allergen-specific immunotherapy (AIT) is an effective treatment. This study aims to evaluate the circulating mas-related G protein-coupled receptor-X2 (MRGPRX2) and matrix metalloproteinase-12 (MMP-12) levels in evaluating disease severity and predicting efficacy of SLIT in AR patients. Methods. We enrolled 110 moderate-severe persist AR patients (AR group) and 40 healthy controls (HC group). Circulating levels of MRGPRX2 and MMP-12 were measured, and their associations with disease severity were evaluated. All AR patien

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Lim, S. S., H. M. Zu, and H. S. Loh. "Chitosan-TiO₂ nanotubes scaffolds for proliferation and early differentiation of MG63 by functionalization with fetal bovine serum." IOP Conference Series: Materials Science and Engineering 1195, no. 1 (2021): 012041. http://dx.doi.org/10.1088/1757-899x/1195/1/012041.

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Abstract Scaffolds have been used as alternative biomaterials to overcome physiological bone disorders. Production of scaffolds has been challenging to fulfil the following criteria: biodegradability, mechanical sustainability, and biocompatibility. For cellular interaction, protein adsorbed on scaffold surface is important for osteoblastic activities. This study aimed to functionalize chitosan-TiO2 nanotubes scaffolds with fetal bovine serum and investigate in vitro efficacy of such scaffolds with fetal bovine serum. Chitosan-TiO2 nanotubes scaffolds were prepared via direct blending and lyop

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TAŞ, Nurmuhammet. "A Meta-analysis on the Efficacy of Various Medicated Treatment Options for Osteoporosis." Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 12, no. 3 (2023): 1131–40. http://dx.doi.org/10.37989/gumussagbil.1346550.

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Bu meta-analizin amacı, osteoporoz için farklı tedavi seçeneklerini gözden geçirmek ve değerlendirmek, etkinliklerini incelemektir. Özellikle, osteoporoz tedavisinde D vitamini, bifosfonatlar, odanacatib, neridronat, teriparatid ve raloksifenin kullanımının tedavi sürecindeki etkinliği araştırılmaktadır. Bu amaçla mevcut araştırmaların harmanlanarak yorumlanmasına olanak sunan meta-analiz yöntemi kullanılmıştır. Çalışmaya 10 birincil çalışma dâhil edilmiştir. Çalışma, osteoporoz ilaçlarının serum phosphate, sCTX ve Serum 25(OH)D değerleri üzerindeki etkisini değerlendirmeyi amaçlamıştır. Bulgu

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Baltzer, Axel W. A., Martin S. Ostapczuk, Daniel Stosch, Florian Seidel, and Markus Granrath. "A new treatment for hip osteoarthritis: clinical evidence for the efficacy of autologous conditioned serum." Orthopedic Reviews 5, no. 2 (2013): 13. http://dx.doi.org/10.4081/or.2013.e13.

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The purpose of the present study was to investigate the effect of intra-articular injections of autologous conditioned serum on human hip osteoarthritis and to test whether a potential treatment effect might be increased by additional injections of steroids and the recombinant interleukin-1 receptor antagonist protein anakinra. We compared the effects of autologous conditioned serum 46 hip osteoarthritis patients), autologous conditioned serum+cortisone (56 patients), and autologous conditioned serum+cortisone+recombinant interleukin-1 receptor antagonist protein (17 patients) in a retrospecti

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Kumar, Kaushal, Sonu Pant, Neha Jacob, Fatima Nishat, and Harshita Dubey. "Comparing the Efficacy of Autologus Blood Serum vs Fibrin Glue in Conjunctival Autograft for Pterygium Excision." International Journal of Science and Research (IJSR) 14, no. 2 (2025): 204–11. https://doi.org/10.21275/sr25201162134.

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Zhao, Meizhen, Li Juanjuan, Fan Weijia, et al. "Expression Levels of MicroRNA-125b in Serum Exosomes of Patients with Asthma of Different Severity and its Diagnostic Significance." Current Drug Metabolism 20, no. 10 (2019): 781–84. http://dx.doi.org/10.2174/1389200220666191021100001.

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Background: This study aimed to investigate the expression levels of microRNA (miRNA)-125b in serum exosomes and its diagnostic efficacy for asthma severity. Methods: The study included 80 patients with untreated asthma and 80 healthy volunteers. The patients were divided into 4 groups according to disease severity: 20 with the intermittent state, 20 with the mildly persistent state, 20 with the moderately persistent state, and 20 with the severely persistent state. The expression levels of miRNA-125b in serum exosomes of each group were detected using a quantitative polymerase chain reaction

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Gayatri, Chude* Asawali Pawar Swati Deshmukh. "Formulation And Evaluation of Face Serum by Using Rose and Beatroot Extract." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1744–53. https://doi.org/10.5281/zenodo.15382816.

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This research paper focuses on the formulation and evaluation of a face serum using rose and beetroot extracts, leveraging their antioxidant, anti-inflammatory and skin-protective properties. The serum was formulated using a combination of rose and beetroot extracts, along with other natural ingredients and its physical and chemical stability, texture, and efficacy were evaluated. This research paper presents the formulation and evaluation of a face serum utilizing rose and beetroot extracts, renowned for their antioxidant, anti-inflammatory and skin-protective properties. The primary objectiv

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McKay, Alannah K. A., Paul S. R. Goods, Martyn J. Binnie, Carmel Goodman, and Peter Peeling. "Examining the decay in serum ferritin following intravenous iron infusion: a retrospective cohort analysis of Olympic sport female athletes." Applied Physiology, Nutrition, and Metabolism 45, no. 10 (2020): 1174–77. http://dx.doi.org/10.1139/apnm-2020-0132.

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The long-term decay rate of serum ferritin post-iron infusion in athletic populations is currently unknown. Here, we modelled the decay rate of serum ferritin in female athletes after an intravenous iron infusion (n = 22). The post-infusion serum ferritin response and the rate of decay was highly variable between athletes; however, we demonstrate that follow-up blood testing at 1 (154 μg/L; 77–300 μg/L) and 6 months (107 μg/L; 54–208 μg/L) post-infusion is appropriate to observe treatment efficacy and effectiveness. Novelty Female athletes should have serum ferritin assessed at 1 and 6 months

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Schroeppel, Thomas J., L. Paige Clement, Danielle L. Barnard, et al. "Propofol Infusion Syndrome: Efficacy of a Prospective Screening Protocol." American Surgeon 84, no. 8 (2018): 1333–38. http://dx.doi.org/10.1177/000313481808400848.

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Propofol infusion syndrome (PIS) is a potentially lethal complication of propofol marked by rhabdomyolysis, metabolic acidosis, and cardiac arrhythmias or collapse. The objective of this study was to determine the effectiveness of a prospective screening protocol to prevent PIS. All trauma patients admitted who received propofol as a continuous infusion were prospectively screened from November 1, 2013 to December 31, 2015. Variables studied included demographics, injury severity, laboratory values, infusion rates, and mortality. Serum creatine phosphokinase (CPK) and lactate were drawn daily.

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Yang, Xiuqin, Yumei Zhang, Hai Lin, Hui Zhong, and Zhihui Wu. "Diagnostic Value of the Triple Combination of Serum Heparin-Binding Protein, Procalcitonin, and C-Reactive Protein in Children with Acute Bacterial Upper Respiratory Tract Infection." Journal of Healthcare Engineering 2022 (March 10, 2022): 1–8. http://dx.doi.org/10.1155/2022/1877960.

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To investigate the role of the triple combination serum heparin-binding protein (HBP), procalcitonin (PCT), and C-reactive protein (CRP) in children with acute bacterial upper respiratory tract infection (ABURTI). A total of 130 children with upper respiratory tract infection admitted to the Department of Pediatrics of Fujian Maternity and Child Health Hospital from September 2019 to January 2021 were selected as the research group. According to the results of pathogenic analysis, children were further subdivided into a bacterial infection group (n = 67) and a viral infection group (n = 63). A

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Elkholy, Rasha A., Reham L. Younis, Alzahraa A. Allam, Rasha Youssef Hagag, and Muhammad Tarek Abdel Ghafar. "Diagnostic efficacy of serum and urinary netrin-1 in the early detection of diabetic nephropathy." Journal of Investigative Medicine 69, no. 6 (2021): 1189–95. http://dx.doi.org/10.1136/jim-2021-001785.

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This study aimed to assess the diagnostic value of serum and urinary netrin-1 in patients with type 2 diabetes mellitus (T2DM) at different stages of diabetic nephropathy (DN) and to compare its efficacy of estimation in serum with that in the urine. This study was carried out on 135 patients with T2DM and 45 healthy subjects. The patients with diabetes were divided according to urinary albumin creatinine ratio (UACR) into: T2DM with normoalbuminuria, incipient DN with microalbuminuria, and overt DN with macroalbuminuria groups. Serum and urinary levels of netrin-1 were measured by ELISA. The

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Thompson, Dennis F., Marsha A. Raebel, Collin D. Freeman, Richard Quintiliani, and Charles H. Nightingale. "Vancomycin Therapeutic Drug Monitoring: Is it Necessary?" Annals of Pharmacotherapy 27, no. 5 (1993): 594–98. http://dx.doi.org/10.1177/106002809302700514.

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OBJECTIVE: To review the literature and assess the validity of obtaining vancomycin serum drug concentrations in patients. DATA SOURCES: A MEDLINE search of the English literature and a bibliographic review of articles pertaining to vancomycin serum concentrations, their use, and the rationale of cited therapeutic ranges. STUDY SELECTION AND DATA EXTRACTION: Studies pertaining to the use of vancomycin concentrations in the clinical setting, methods for predicting these concentrations, and studies that reported efficacy or toxicity associated with vancomycin use and possible correlation of seru

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KUBANOVA, A. A., I. N. LESNAYA, N. V. FRIGO, N. L. KAGANOVA, L. F. ZNAMENSKAYA, and A. A. KUBANOV. "Molecular Markers In Forecasting The Clinical Efficacy Of Infliximab In Psoriasis Patients." Vestnik dermatologii i venerologii 86, no. 1 (2010): 57–66. http://dx.doi.org/10.25208/vdv827.

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Biosamples (skin tissue samples taken from affection foci and blood serum) from 22 patients suffering from severe to medium psoriasis (8 women and 14 men) aged 19-57 treated with Infliximab were analyzed. As for skin tissue samples, the molecular structure of genes TNF-a, TNF-R-I and TNF-R-II, contents of cytokine TNF-a and its soluble receptors (sTNF-RI and sTNF-RII) and proteome composition was analyzed in skin tissue samples; contents of TNF-a, IL2, IL4, IL6, IL-8 and IL-10 were analyzed in the blood serum. The homozygous TT genotype of TNF-R-II gene at the 676 locus and high IL10 level in

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Sim, Jeeho, SeongDae Gong, Geonwoo Kang, et al. "Enhanced Micro-Channeling System via Dissolving Microneedle to Improve Transdermal Serum Delivery for Various Clinical Skincare Treatments." Pharmaceutics 14, no. 12 (2022): 2804. http://dx.doi.org/10.3390/pharmaceutics14122804.

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Topical liquid formulations, dissolving microneedles (DMNs), and microscale needles composed of biodegradable materials have been widely used for the transdermal delivery of active compounds for skincare. However, transdermal active compound delivery by topical liquid formulation application is inhibited by skin barriers, and the skincare efficacy of DMNs is restricted by the low encapsulation capacity and incomplete insertion. In this study, topical serum application via a dissolvable micro-channeling system (DMCS) was used to enhance serum delivery through micro-channels embedded with DMNs.

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Eliseev, M. S., O. V. Zhelyabina, M. N. Chikina, and M. M. Thakokov. "Febuxostat efficacy in patients with gout depending on kidney function." Russian Medical Inquiry 6, no. 3 (2022): 140–47. http://dx.doi.org/10.32364/2587-6821-2022-6-3-140-147.

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Aim: to determine the probability of achieving the target serum uric acid (UA) level during therapy with febuxostat (in the tablet form) in patients with gout stratified depending on kidney function, including patients with type 2 diabetes mellitus (DM2). Patients and Methods: the study included patients over 18 years of age with gout who had not previously taken febuxostat or other urate- lowering drugs for at least 2 weeks before inclusion, with a serum UA level >360 μmoL/L. All were prescribed with febuxostat in the tablet form 80 mg/day. If the target serum UA level was not reached (&lt

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Marcus, F. I. "Titrating cardiovascular drugs." Clinical Chemistry 42, no. 8 (1996): 1312–15. http://dx.doi.org/10.1093/clinchem/42.8.1312.

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Abstract Titrating cardiovascular drugs is important to ensure efficacy and to minimize the risk of toxicity. A serum assay is extremely useful to guide digoxin therapy. Assessment of the effect of warfarin on blood clotting should be used to adjust dose. Serum cholesterol and lipid measurements guide therapy with antilipemic agents. The antihypertensive drugs, beta blockers, calcium channel blockers, and vasodilators can be assessed by their clinical effects. There is no strict relation between serum concentration of antiarrhythmic drugs and their effects, nor is it clear that the long-term e

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Kasiyati, K., W. Manalu, S. Sumiati, and D. R. Ekastuti. "EFFICACY OF CURCUMIN AND MONOCHROMATIC LIGHT IN IMPROVING LIVER FUNCTIONS OF SEXUALLY MATURE MAGELANG DUCKS." Journal of the Indonesian Tropical Animal Agriculture 41, no. 3 (2016): 153–60. http://dx.doi.org/10.14710/jitaa.41.3.153-160.

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The liver of female poultry has a vital role as an organ for biosynthesis of the yolk precursor and has a greater chance of experiencing cellular damages. This experiment was designed to study the uses of curcumin and monochromatic light in suppressing liver destruction during the period of yolk biosynthesis in Magelang ducks. One hundred and ninety two female Magelang ducks were assigned into a completely randomized design with a 4x4 factorial arrangement. The first factor was dose of curcumin supplementation consisted of 4 levels i.e., 0, 9, 18, and 36 mg. The second factor was the color of

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Murphy, Philip T., and Philip W. Murphy. "Serum ferritin to predict efficacy of adult HLH induction therapy." Annals of Medicine 54, no. 1 (2022): 1561. http://dx.doi.org/10.1080/07853890.2022.2081870.

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