Academic literature on the topic 'Serum LDH: Pleural fluid ADA'

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Journal articles on the topic "Serum LDH: Pleural fluid ADA"

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Verma, Akash, John Abisheganaden, and R. W. Light. "Identifying Malignant Pleural Effusion by A Cancer Ratio (Serum LDH: Pleural Fluid ADA Ratio)." Lung 194, no. 1 (2015): 147–53. http://dx.doi.org/10.1007/s00408-015-9831-6.

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Verma, Akash, Rucha S. Dagaonkar, Dominic Marshall, John Abisheganaden, and R. W. Light. "Differentiating Malignant from Tubercular Pleural Effusion by Cancer Ratio Plus (Cancer Ratio: Pleural Lymphocyte Count)." Canadian Respiratory Journal 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/7348239.

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Background. We performed prospective validation of the cancer ratio (serum LDH : pleural ADA ratio), previously reported as predictive of malignant effusion retrospectively, and assessed the effect of combining it with “pleural lymphocyte count” in diagnosing malignant pleural effusion (MPE).Methods. Prospective cohort study of patients hospitalized with lymphocyte predominant exudative pleural effusion in 2015.Results. 118 patients, 84 (71.2%) having MPE and 34 (28.8%) having tuberculous pleural effusion (TPE), were analysed. In multivariate logistic regression analysis, cancer ratio, serum L
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International, Journal of Medical Science and Innovative Research (IJMSIR). "A Cross Sectional Study to Determine The Efficacy of Serum LDH: Pleural Fluid Ada Ratio As A Biomarker of Malignant Pleural Effusion in IRD, SMS Medical College, Jaipur." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 4 (2024): 151–58. https://doi.org/10.5281/zenodo.15422923.

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<strong>Abstract</strong> <strong>Introduction</strong>: The malignant pleural effusion is one of the most common causes of exudative pleural effusion. There is no accurate and commonly accepted biochemical marker of MPE, hence using common parameters two ratio serum LDH: pleural fluid ADA (cancer ratio) and cancer ratio: pleural fluid lymphocyte count (cancer ratio plus) derived and their efficacy in identification of MPE is studied. <strong>Methods</strong>: 60 undiagnosed pleural effusion patients were studied in a hospital based cross sectional observational analytical study. The values of
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Nishanth, P. S., Thomas Vadakkan Devassy, and Tessa Jose. "Diagnostic utility of cancer ratio in differentiating malignant from non-malignant pleural effusions in a tertiary care centre in central Kerala." International Journal of Advances in Medicine 9, no. 2 (2022): 102. http://dx.doi.org/10.18203/2349-3933.ijam20220116.

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Background: Malignant pleural effusion (MPE) is a common clinical condition observed in patients suffering from malignant diseases. None of the tumour markers have both high sensitivity and specificity. A retrospective study on patients with pleural effusion was done to evaluate the diagnostic accuracy of Cancer ratio (CR) in diagnosing MPE.Methods:A retrospective analysis of patients with undiagnosed exudative pleural effusion was done. Results of serum Lactate dehydrogenase (LDH), pleural fluid Adenosine deaminase (ADA), pleural fluid analysis such as cytology and histopathology reports of p
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Amer, Ahmed M., Kareeman G. Mohamed, Passant A. Shibel, and Hussein E. Fayiad. "Role of cancer ratio (serum LDH/pleural ADA) and carcinoembryonic antigen in diagnosis of malignant pleural effusion." Egyptian Journal of Chest Diseases and Tuberculosis 73, no. 2 (2024): 132–35. http://dx.doi.org/10.4103/ecdt.ecdt_75_23.

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Abstract Background Pleural effusion may be malignant or nonmalignant, Cytology has been used in malignant pleural effusion (MPE) diagnosis due to its high specificity. Its sensitivity is about 0.6. Cancer ratio (CR) and carcinoembryonic antigen (CEA) may be used in MPE diagnosis. Aim Evaluate the role of CR and CEA as diagnostic markers of MPE and their role in differentiating different types of MPE. Patients and methods This cross-sectional study included 70 patients with pleural effusion admitted to Chest Department, Kasr Alainy Faculty of Medicine, Cairo University. Thirty-five patients ha
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Gao, Lijuan, Wujun Wang, Ying Zhang, et al. "Adenosine deaminase-based measurement in the differential diagnosis of pleural effusion: a multicenter retrospective study." Therapeutic Advances in Respiratory Disease 17 (January 2023): 175346662311557. http://dx.doi.org/10.1177/17534666231155747.

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Introduction: The differential diagnosis of pleural effusion is difficult, and studies have reported on the potential role of adenosine deaminase (ADA) in the differential diagnosis of undiagnosed pleural effusion. This retrospective study aimed to investigate the diagnostic role of ADA in pleural effusion. Methods: 266 patients with pleural effusion from three centers were enrolled. The concentrations of ADA and lactate dehydrogenase (LDH) were measured in pleural fluids and serum samples of the patients. The diagnostic performance of ADA-based measurement for tuberculous pleural effusion (TP
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Singh, Jaspreet, Khushdeep Singh, Rincal Saini, Umesh Kumar, Shiv Sharma, and Harvinder Singh. "Diagnostic role of different biochemical parameters in pleural effusion." International Journal of Clinical Biochemistry and Research 9, no. 4 (2022): 291–94. http://dx.doi.org/10.18231/j.ijcbr.2022.057.

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A pleural effusion, an excessive accumulation of fluid in the pleural space, indicates an imbalance between pleural fluid formation and removal. For diagnosing and treatment plan, pleural effusions have to be classified into transudate and exudate. The aim of present study was to analyze various biochemical parameters (LDH, pH, Glucose, Triglycerides, Cholesterol, Creatinine, Amylase and ADA) in pleural fluid and to correlate these Biochemical parameters with diagnosis of the patients. The study was a hospital based descriptive study. The study was conducted over a period of one year on 100 sa
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Babapour, Behzad, Mohammad Mirzaaghazadeh, Bita Shahbazzadegan, Hadi Mohsenifar, Alireza Mohammadzadeh, and Bijan Zamani. "Evaluation of diagnostic value of n-terminal pro brain natriuretic peptide in pleural fluid with cardiac origin." International Journal Of Community Medicine And Public Health 5, no. 3 (2018): 912. http://dx.doi.org/10.18203/2394-6040.ijcmph20180746.

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Background: Pleural effusion is a common finding in patients. For a long time, a light criterion is used to analysis of pleural effusion for separation of transudative from exudative fluid. Sensitivity of light criteria is very high to determine exudative pleural effusion (98%). However, the ability of these criteria for ruling out of transudative effusions is low. For this reason, this study was carried out to determine the level of NT-proBNP in pleural fluid.Methods: A descriptive-analytic study was carried out on 21 patients with complaints of shortness of breath and diagnosis of pleural ef
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Bai, Wenjing, Jiangnan Chen, Yijian Mao, et al. "A Predictive Model for the Identification of Cardiac Effusions Misclassified by Light’s Criteria." Laboratory Medicine 51, no. 4 (2019): 370–76. http://dx.doi.org/10.1093/labmed/lmz072.

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Abstract Objectives The application of Light’s criteria misidentifies approximately 30% of transudates as exudates, particularly in patients on diuretics with cardiac effusions. The purpose of this study was to establish a predictive model to effectively identify cardiac effusions misclassified by Light’s criteria. Methods We retrospectively studied 675 consecutive patients with pleural effusion diagnosed by Light’s criteria as exudates, of which 43 were heart failure patients. A multivariate logistic model was developed to predict cardiac effusions. The performance of the predictive model was
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Cojocaru, Viorica, Elena Dantes, Mariana Gabriela Novac, et al. "The Value of Adenosine Deaminase Enzime Level in the Positive Diagnosis of Tuberculous Pleural Effusion." Revista de Chimie 69, no. 12 (2019): 3688–91. http://dx.doi.org/10.37358/rc.18.12.6820.

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The etiologic diagnosis of pleural effusion is often difficult, requiring invasive investigations to determine it. In Romania, tuberculosis is a frequent cause of pleural effusion, with the diagnosis of certainty being based on the bacteriological or histopathological examination. Adenosine deaminase (ADA) is an enzyme found in T lymphocytes, stimulated by Mycobacterium tuberculosis, which is why it is considered to be an essential marker of etiologic diagnosis in countries where the TB endemic is elevated. A case-control study was conducted in the Clinical Pneumophthisiology Hospital of Const
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Book chapters on the topic "Serum LDH: Pleural fluid ADA"

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Davies, Robert J. O., Fergus V. Gleeson, Y. C. Gary Lee, Jose Porcel, and Fraser Brims. "Pleural diseases." In Oxford Textbook of Medicine. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199204854.003.1817_update_001.

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Case History—A 40 yr old woman with pleuritic chest pain. This is a common clinical problem which can complicate a range of lung and systemic diseases. Most cases can be diagnosed by pleural fluid analysis and pleural biopsy, with Light’s criteria making it possible to discriminate between transudates and exudates. These state that a pleural effusion is an exudate if any of the following are present: (1) pleural fluid to serum protein ratio greater than 0.5; (2) pleural fluid lactate dehydrogenase (LDH) greater than two-thirds of the upper limit of normal serum LDH; (3) pleural fluid to serum
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