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Dissertations / Theses on the topic 'Serum lipids and lipoproteins'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Marsh, M. S. "The effect of different regimens of hormone replacement therapy on serum lipids and lipoproteins in postmenopausal women." Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297209.

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2

Persons, Jane Elizabeth. "Characterizing the relationship between low serum low-density lipoprotein and depressive symptoms." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/5600.

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The purpose of this study was to resolve a critical gap in depression literature through assessment of the temporal relationship between depression and low LDL. A systematic review and meta-analysis was conducted to investigate the overall cross-sectional association between serum LDL and depression. Inconsistent findings suggest that more work must be done to clarify the link between LDL and depression. Next, Cox regression was used to explore the association between LDL and the subsequent onset of depressive symptoms within a subset of the Women’s Health Initiative cohort and evaluate the po

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3

Norrgård, Örjan. "Familial occurrence of abdominal aortic aneurysms." Doctoral thesis, Umeå universitet, Kirurgi, 1985. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100555.

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The occurrence of clinically diagnosed and/or ruptured abdominal aortic aneurysms (AAAs) in the families of 220 patients with AAAs, treated at the Surgical Clinic, University Hospital of Umeå in the northern part of Sweden during the years 1965-82, was studied. A questionnaire concerning the blood relatives was answered by 87/89 patients. 16/87 patients (18%) had blood relatives with AAAs. In 14 families one blood relative was affected, and in 2 families two blood relatives were affected. First degree relatives were affected in 9/87 cases (10%), and second degree relatives in 7/87 cases (8%).

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4

Slunga, Lisbeth. "Serum lipoprotein(a) in relation to ischemic heart disease and associated risk factors." Doctoral thesis, Umeå universitet, Klinisk kemi, 1993. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-101298.

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Lipoprotein(a) (Lp(a)) consists of an LDL-like particle and the specific protein apo(a), which is very similar to plasminogen. Apo(a) contains repeated kringle structures and a serine protease domain, which cannot be activated by t-PA. Lp(a) is considered to be a predictor for atherosclerotic disease. It has been found incorporated in atherosclerotic plaques and inhibits in vitro fibrinolysis. Lp(a) was determined in 1527 randomly selected individuals participating in the Northern Sweden WHO-MONICA project. A weak but significant relation between Lp(a) and increasing age was found. Menopausal

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5

Tanyanyiwa, Donald Moshen. "Apolipoprotein E variants, plasma lipids, lipoproteins and dysApolipoprotein E variants, plasma lipids, lipoproteins and dysβLipoproteinaemia during pregnancy in Zimbabwean women". Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/2703.

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Includes bibliographical references (leaves 117-138).<br>This study of pregnant women in Zimbabwe therefore set itself the following aims: To describe lipid and lipoproteins during and after pregnancy, To examine the prevalence of apoE variants, To evaluate dysβlipoproteinaemia in pregnancy, The correlation between dysβplipoproteinaemia and the apoE genotypes. This is the first study to systematically examine lipids and lipoproteins during pregnancy in black Africans.

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6

Sattar, Naveed Amjid. "Lipids and lipoproteins in normal and complicated pregnancies." Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244436.

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7

Myers, Christine Lee. "Detection of oxidation in human serum lipoproteins." Texas A&M University, 2005. http://hdl.handle.net/1969.1/3303.

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A method for the oxidation of lipoproteins in vitro was developed using the free radical initiator, 2,2?-azobis-(2-amidinopropane) dihydrochloride (AAPH). Following in vitro oxidation, the susceptibility to oxidation of the serum samples was studied using density gradient ultracentifugation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). Shifts in mean buoyant density of the lipoprotein particles, specifically low density lipoprotein (LDL) and high density lipoprotein (HDL), were observed in the density profile following centrifugation. Th

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8

Ma, Yanshan. "Factors Influencing the Oxidation of Lipoproteins and Plasma Lipids." Digital Commons @ East Tennessee State University, 1994. https://dc.etsu.edu/etd/2724.

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The hypothesis that antioxidant vitamins (ascorbate and tocopherols) along with urate protect blood plasma lipids from oxidation was tested. Dietary fat is also an important factor influencing plasma lipid peroxidation. The purpose of this study was to investigate the role of plasma antioxidants and dietary fat on low density lipoprotein (LDL) and plasma lipid oxidation. In the first part of this study, we compared the ability of urate and ascorbate to protect human LDL from in vitro oxidation. LDL oxidation was initiated by 15 mM of a water soluble azo-initiator in the presenc

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9

Bocchino, Lisa. "The effects of exercise on serum lipoproteins in postmenopausal women." Scholarly Commons, 1989. https://scholarlycommons.pacific.edu/uop_etds/2190.

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A lot of attention has been focused on reducing cholesteric problems before individuals reach middle age, but is it not possible to reduce the risk factors for CHD after middle age? This study was initiated to determine id moderate exercise had an effect on the serum lipoproteins in postmenopausal women. Plasma concentrations of glucose, triglyceride (TRIG), TC, HDL, and LDL were measured before and after a monitored regime of moderate exercise.

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10

Razay, George. "Insulin, lipids and lipoproteins in relation to cardiovascular risk and Alzheimer's disease." Thesis, University of Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295520.

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11

Gelaye, Bizu, Torrealva Gloria T. Larrabure, Chunfang Qiu, et al. "Fasting lipid and lipoproteins concentrations in pregnant women with a history of migraine." John Wiley & Sons, Inc, 2015. http://hdl.handle.net/10757/610594.

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Migraine is associated with a number of cardiometabolic risk factors including abnormalities in lipid metabolism. However, little is known about these associations among pregnant migraineurs. We conducted the present study to evaluate the extent to which altered lipid profiles are associated with history of migraine among pregnant women.

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12

Ahmad, Aryati. "Studies on the effects of dietary carbohydrates on human plasma lipids and lipoproteins." Thesis, University of Surrey, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590656.

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The dietary recommendation to replace saturated fat with carbohydrate as a means of reducing cardiovascular risk, has been hindered by the adverse effect of dietary extrinsic sugars on plasma lipids. The project described in this thesis, formed part of a BBSRC- funded trial to examine the impact of dietary extrinsic sugars on lipoprotein kinetics. A key objective of this project was to design and deliver two diets, high and low in extrinsic sugars, to test the hypothesis of the main trial; that dietary sugars influence plasma lipids, via differential effects on the kinetics of plasma lipoprote

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13

Harman, Nicola Louise. "The influence of dietary modifications and weight loss on plasma lipids and lipoproteins." Thesis, University of Surrey, 2007. http://epubs.surrey.ac.uk/843976/.

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The studies presented in this thesis investigated dietary strategies to reduce cardiovascular (CV) risk associated with atherogenic dyslipidaemia. The thesis also describes the development of a new method for the separation of the principal HDL subclasses. The 'RISCK' study five examined the effects of five diets, differing in the type and amount of dietary fat and carbohydrate, on plasma lipids in subjects at risk of developing metabolic syndrome. All diets showed a significant reduction in serum total, and LDL cholesterol. Whilst no diet was superior in its lipid-lowering effect, the two low

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14

Carpenter, Alexis Anne. "The separation of lipoproteins and the determination of cholesterol in human serum /." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74624.

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A flow-injection system is described which employs immobilized cholesterol esterase and cholesterol oxidase for the determination of total serum cholesterol. Hydrogen peroxide generated by the enzymatic reaction is measured directly at a home-made amperometric thin-layer flow-cell held at +600 mV vs Ag/AgCl. Serum samples are passed through an anion exchange resin to remove possible interferences prior to detection. The accuracy and precision of the system were evaluated with the use of certified reference materials for serum cholesterol and were found to conform to the recommended guidelines

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15

Chandra, Richa. "The analysis of triglyceride-rich lipoproteins in human serum for clinical studies." [College Station, Tex. : Texas A&M University, 2006. http://hdl.handle.net/1969.1/ETD-TAMU-1745.

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16

Chen, Pak-lam Sammy. "Influence of microsomal triglyceride transfer protein (MTP) gene polymorphism on plasma lipids and lipoproteins in southern Chinese." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31980922.

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17

Åkerlund, Börje. "Impact of sepsis and HIV-1 infection on neutrophil radical production, lipids and lipoproteins /." Stockholm, 1998. http://diss.kib.ki.se/search/diss.se.cfm?19980529aker.

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18

Prindiville, John S. "Circulating lipoproteins and tissue lipids: Effects of gemfibrozil on lipid metabolism in rainbow trout." Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28555.

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Lipids support crucial functions in teleost fish, including the production of energy; lipoproteins support the movement of lipids through the vascular system. The objective of this thesis was to determine if gemfibrozil (GEM), a mammalian PPARalpha agonist pharmaceutical, could alter the circulating lipoproteins and tissue lipid metabolism in the rainbow trout, Oncorhynchus mykiss. Injections of GEM lowered the concentration of lipoproteins and changed their size distribution, lipid and fatty acid content. These changes were associated with an increased lipoprotein lipase transcript level but

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19

Ng, Ai-Leng. "Comparisons of serum lipid levels and dietary lipid intakes of parents and children." Thesis, Virginia Tech, 1988. http://hdl.handle.net/10919/43259.

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Fifty-seven subjects from 14 families participated in a study designed to investigate similarities and differences between parents and children residing with them relative to their serum lipid levels and dietary lipid intakes. To participate, at least one of the parents needed to have a serum total cholesterol of at least 240 mg/dL. Fasting blood samples obtained from the participants were analyzed for serum total cholesterol, HDL-C, LDL-C, and VLDL-C levels. Anthropometric measurements and blood pressure readings also were taken. Dietary records, questionnaires on lifestyle, health habits,

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20

Al-Najadah, Rabah. "The effect of exercise and fish oil capsules on serum blood lipid and lipoprotein levels in pre and post menopausal women." Thesis, Bangor University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332402.

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21

Rauchhaus, Mathias. "Studies on bacterial endotoxin and serum lipoproteins in patients with chronic heart failure." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407049.

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22

Chen, Pak-lam Sammy, and 陳栢林. "Influence of microsomal triglyceride transfer protein (MTP) gene polymorphism on plasma lipids and lipoproteins in southern Chinese." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31980922.

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23

Hagström, Emil. "Metabolic disturbances in relation to serum calcium and primary hyperparathyroidism /." Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6893.

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24

Chanti-Ketterl, Marianne. "Lipoproteins and Health Outcomes: Cognitive and Physical Function in Older Adults." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5920.

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Cardiovascular health is a major determinant of quality of life and mortality, especially in older adulthood. With the world’s oldest population increasing at expedited rates, challenges from cardiovascular conditions and its implications are spawning. Although it is well known that dyslipidemia may lead to cardiac events, less is known about the effects on cognitive and physical function in older adults. Epidemiological studies show that optimizing current preventive strategies even at older ages may reduce the incidence of cardiovascular comorbidity (e.g. hypertension, stroke) and increase q

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25

Suresh, Swetha. "Probing protein-lipid interactions using atomic force microscopy." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609231.

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26

Jordan, Julie Ann. "Altered feeding pattern:its effect on selected blood lipids in humans." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/91034.

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Seventeen males participated in an investigation comparing the effects of a three meal per day feeding pattern versus a six meal per day feeding pattern on a serum lipid profile. During a two week acclimation period three meals per day were consumed by all subjects. The subjects were then divided into two groups. Group I consumed three meals per day for six weeks while group II consumed six meals per day for the same amount of time. The two groups then reversed feeding patterns for an additional six week period. Subjects completed five four-day food records which were analyzed qualitatively. T

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27

Mansfield, Elizabeth 1960. "A comparison of dietary intake, plasma CETP mass and HDL composition between exercising and sedentary males." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=42299.

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In a cross-sectional study we examined Iipoprotein composition and CETP mass in 15 sedentary and 12 exercising, healthy male volunteers, aged between 17-35 years. The exercising group were defined as individuals participating in at least five weekly 45 minute exercise sessions of an aerobic nature (60-85% estimated maximal oxygen uptake). The sedentary subjects were only irregularly engaged in bouts of physical activity, not more than 45 minutes per week. Seasonal data were collected: one data collection in the fall and one in the spring. A 20 day food and exercise journal was maintained durin

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28

Pocathikorn, Anothai. "Low density lipoprotein receptor-related protein (LRP) and its mRNA : influence of genetic polymorphisms, a fat load and statin therapy /." Connect to this title, 2005. http://theses.library.uwa.edu.au/adt-WU2006.0117.

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29

Kaushik, Shalini Mathews Suresh T. "Ser312 fetuin-A phosphorylation and its association with serum lipids in metabolic syndrome." Auburn, Ala, 2008. http://repo.lib.auburn.edu/EtdRoot/2008/SUMMER/Nutrition_and_Food_Science/Thesis/Kaushik_Shalini_4.pdf.

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30

Koska, Juraj, Hussein Yassine, Olgica Trenchevska, et al. "Disialylated apolipoprotein C-III proteoform is associated with improved lipids in prediabetes and type 2 diabetes." AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2016. http://hdl.handle.net/10150/614755.

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The apoC-III proteoform containing two sialic acid residues (apoC-III2) has different in vitro effects on lipid metabolism compared with asialylated (apoC-III0) or the most abundant monosialylated (apoC-III1) proteoforms. Cross-sectional and longitudinal associations between plasma apoC-III proteoforms (by mass spectrometric immunoassay) and plasma lipids were tested in two randomized clinical trials: ACT NOW, a study of pioglitazone in subjects with impaired glucose tolerance (n = 531), and RACED (n = 296), a study of intensive glycemic control and atherosclerosis in type 2 diabetes patients.

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31

Rajaratnam, Radhakrishnan. "Impact of serum squalene, postprandial lipoproteins, and cholesterol metabolism on coronary artery disease in postmenopausal women." Helsinki : University of Helsinki, 2000. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/rajaratnam/.

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32

Bass, Roger Thompson II. "Effects of Vitamin E Supplementation in Late Gestation Cattle and Evaluation of Vitamin E, Cholesterol, and Phospholipid Relationships in Bovine Serum and Serum Lipoproteins." Diss., Virginia Tech, 1999. http://hdl.handle.net/10919/28313.

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The effects of vitamin E supplementation during late gestation were evaluated in dairy or beef cattle in three experiments. Dairy cows were injected with vitamin E and selenium (Se) in one study; beef cows were offered oral vitamin E supplementation via a free-choice vitamin-mineral mix in two studies. Breed-related effects were also evaluated. Jerseys had higher blood Se and lower serum vitamin E concentrations than Holsteins at dry-off and higher blood Se concentrations than Holsteins 3-4 weeks pre-calving and at calving. Selenium supplementation increased blood Se concentrations at calv

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33

Clayton, Daniel John. "Spectroscopic studies of apolipoprotein e and the low-density lipoprotein receptor /." [St. Lucia, Qld.], 2001. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16846.pdf.

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34

Hagström, Emil. "Metabolic Disturbances in Relation to Serum Calcium and Primary Hyperparathyroidism." Doctoral thesis, Uppsala University, Department of Surgical Sciences, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6893.

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<p>Primary hyperparathyroidism (pHPT), characterized by elevated serum levels of calcium and parathyroid hormone (PTH), is associated with a number of metabolic derangements causing secondary manifestations. These include osteoporosis and increased risk of fractures, but also risk factors for cardiovascular morbidity and mortality. These risk factors include impaired glucose tolerance (IGT), dyslipidemia, increased body mass index and hypertension. While the skeletal abnormalities are mainly due to elevated PTH, the latter disturbances are still unexplained. Non-insulin dependent diabetes mell

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35

Khaliullina-Skultety, Helena. "Patched-mediated regulation of Smoothened trafficking and activity by Lipophorin-derived lipids." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-65291.

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Hedgehog is a lipid-linked morphogen that is carried on lipoprotein particles and that regulates both patterning and proliferation in a wide variety of vertebrate and invertebrate tissues. Hyperactivity of Hedgehog signaling causes numerous forms of cancer. Hedgehog acts by binding to its receptor Patched, relieving the suppression of Smoothened and initiating Smoothened signaling. The mechanism by which Patched represses Smoothened has been unclear, but correlates with reduced Smoothened levels on the basolateral membrane. The structural homology of Patched with the Niemann-Pick-Type C1 prote

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36

Maisonet, Mildred, Simo Näyhä, Debbie A. Lawlor, and Michele Marcus. "Prenatal Exposures to Perfluoroalkyl Acids and Serum Lipids at Ages 7 and 15 in Females." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/29.

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Background In some cross-sectional epidemiologic studies the shape of the association between serum concentrations of perfluoroalkyl acids (PFAAs) and lipids suggests departures from linearity. Objectives We used statistical approaches allowing for non-linearity to determine associations of prenatal exposures of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) with lipid concentrations. Methods PFAAs were measured in serum from pregnant women collected in 1991–1992 at enrollment in the Avon Longitudinal Study of Parents and Children and lipids in serum from their daughter

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37

Bartlett, Betty Jean Miller. "Relationships between measures of body fatness, body fat distribution and serum lipids in healthy elderly /." The Ohio State University, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487683756127619.

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38

DeLany, James Patrick. "Effects of fish oil on serum lipids in college men in a controlled feeding trial /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487268021749804.

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39

Zakiev, Emil. "Omics of human plasma lipoproteins : role in cardiometabolic diseases." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS436.

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Omics vise à la caractérisation et à la quantification collectives de pools de molécules biologiques qui traduisent notre compréhension de la structure et de la fonction d'un organisme ou d'une partie de celui-ci. Les lipoprotéines plasmatiques humaines jouent un rôle important dans le développement de la résistance à l'insuline, de la dyslipidémie, de l'hypertension, de l'adiposité centrale et de maladie cardiovasculaire (MCV), le tout collectivement appelé maladie cardiométabolique (MCM). En effet, on sait que la diminution des taux de cholestérol lipoprotéine de haute densité (LHD) et l’aug

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40

Júnior, Antonio Carlos de Arruda Leite. "Avaliação de aspectos funcionais da lipoproteína de alta densidade (HDL) e suas subfrações em pacientes com doença arterial coronária." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-01072015-103450/.

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Estudos clínicos e epidemiológicos indicam que baixas concentrações plasmáticas da lipoproteína de alta densidade (HDL) estão forte e independentemente associadas a uma maior incidência de doença arterial coronária (DAC). Entretanto, o insucesso dos agentes que são capazes de aumentar a concentração de HDL-C sugere que a funcionalidade da HDL pode representar um alvo terapêutico mais apropriado. Para a avaliação de um dos aspectos funcionais da HDL, o presente trabalho descreve o desenvolvimento de um método de grande praticidade que permite uma visão integrada de uma etapa fundamental do meta

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41

Stricker, Lindsey A. "Suboptimal Nutrient Intake in HIV-Infected Youth and Associations with Serum Lipid Profiles and HIV-Related Factors." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/nutrition_theses/38.

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Background: Few studies have evaluated habitual nutrient intake among HIV-infected youth in the United States, even though diet may influence disease progression and chronic complication risk. Objective: This study determined micro- and macronutrient intake in HIV-infected youth, and investigated relationships among nutrient intake, demographics, lipid profiles, and HIV-related factors. Design: HIV-infected subjects and healthy controls 1-25 years old were prospectively enrolled. Concomitant demographic, clinical and laboratory data were collected. Nutrient intake was assessed via 24-hr dietar

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42

Black, Melinda Lori. "Cholesterol lowering effects of bovine serum immunoglobulin in human participants with mild hypercholesterolemia." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4153.

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Hypercholesterolemia is a major risk factor for cardiovascular disease (CVD). Interestingly, the consumption of dairy products, namely milk, has been shown to lower cholesterol. The mechanism of action surrounding this observation has been attributed to the protein fraction of milk. While there have been many studies evaluating the effects of dietary protein sources on cholesterol concentrations, few studies have evaluated specific animal protein components and no human clinical studies regarding the effects of animal plasma protein fractions on cholesterol metabolism have been conducted. This

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43

Skinner, Sven E. "Cellular actions of serum lipids in atherogenesis and hypertension-role of pericytes as an additional tool /." [S.l.] : [s.n.], 1998. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=12534.

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44

Augustin, Livia S. A. "The effect of wheat bran particle size and wheat protein on serum lipids and colonic health." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0014/MQ40821.pdf.

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45

Wickman, Sanna. "Aromatase inhibition in boys with delayed puberty effects on growth, maturation, bone, serum lipids, and insulin." Helsinki : University of Helsinki, 2003. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/wickman/.

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46

Ouali, Mustapha. "Cationic lipids involved in gene transfer increase intracellular calcium level." Doctoral thesis, Universite Libre de Bruxelles, 2007. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210739.

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Cationic lipids are efficient tools to introduce nucleic acids and proteins into cells. Elucidation of the mechanism and cellular pathways associated to such a transport has been relatively slow, even though significant progress has been made in the characterization of the intracellular trafficking of cationic lipid/DNA complexes. Surprisingly, little is known about the effects of these delivery vectors on cell functioning. In the present thesis, we show that cationic lipids and cationic lipid/DNA complexes strongly increase the intracellular Ca2+ concentration. The end point of the Ca2+ incre

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47

Dikotope, Sekgothe Abram. "Response of serum lipids to a fat meal in Black South African subjects with different apoe genotypes." Thesis, University of Limpopo (Turfloop Campus), 2013. http://hdl.handle.net/10386/1059.

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Thesis (M.Sc. (Chemical Pathology)) --University of Limpopo, 2013<br>Objectives The present study investigated how the serum lipids responded to a high-fat meal in black South African subjects with different APOE genotypes, a population that until recently was reported to be consuming a traditional diet of low fat and high carbohydrates. Methods Sixty students (males and females) of the University of Limpopo, Turfloop Campus were successfully genotyped using Restriction Fragment Length Polymorphism (RFLP) and grouped into four APOE genotype groups; ε2, ε2/ε4, ε3 and ε4. Only thirty-three

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48

Noborn, Fredrik. "Heparan Sulfate Dependent Mechanisms of Amyloidosis." Doctoral thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-168309.

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A common theme in amyloid disorders is the deposition of disease-specific protein aggregates in tissues. Amyloid proteins bind to heparan sulfate (HS), a sulfated glycosaminoglycan, and HS has been found to promote the aggregation process. The present work relates to HS mediated mechanisms of amyloidosis, particularly transthyretin (TTR) amyloidosis, AA-amyloidosis and Alzheimer’s disease (AD). TTR is a transport protein present in the blood and cerebrospinal fluid, which under unclear circumstances can deposit as amyloid in the myocardium of elderly individuals. Examination of cardiac tissue

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49

Saltos, Etta Angel. "Factors affecting serum lipid levels in renal patients undergoing maintenance hemodialysis or continuous ambulatory peritoneal dialysis treatments /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487263399027131.

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50

Fleenor, Bradley S. "The effects of policosanol on reaction time, force production, and the blood lipid profile." Virtual Press, 2002. http://liblink.bsu.edu/uhtbin/catkey/1231340.

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Thirty recreationally active individuals, 16 males and 14 females, participated in the study to examine the effects of policosanol supplementation on reaction time, force production and the blood lipid profile. The subjects were matched based on height, weight. gender, current physical activity level and body fat percentage. The matched subjects where randomly assigned to either the policosanol or placebo group. Supplementation period lasted 8 weeks with reaction and decision time measurements taken at baseline, weeks 2, 4, 6 and 8. Force production was evaluated with the Cybex Dynamometer at

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