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1

Lee, Seung Wook, Tae Soo Kim, Mi-Ja Kim, and Jae Hwan Lee. "Study on the Factors Influencing the Changes of Sesamol and Sesamolin in Sesame Oils during Thermal Oxidation." Food Engineering Progress 15, no. 4 (2011): 420–25. http://dx.doi.org/10.13050/foodengprog.2011.15.4.420.

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Addition effects of free fatty acids (FFA), glycerol, monoacylglycerol (MAG), sesamol, and aqueous extracts of sesame seed meal (ASM) on the changes of sesamol and sesamolin were determined in thermally oxidized sesame oil (SO) at 180°C for 90 min. Sesamol and sesamolin in SO were analyzed by high performance liquid chromatography (HPLC). As the concentration of FFA and MAG in SO increased up to 10% (w/w), the concentration of sesamol increased significantly by 0.94 and 0.70 mM, respectively (p < 0.05) whereas sesamol in control samples increased by 0.09 mM for 90 min oxidation. Sesamolin i
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2

Rosalina, Reny, and Natthida Weerapreeyakul. "An Insight into Sesamolin: Physicochemical Properties, Pharmacological Activities, and Future Research Prospects." Molecules 26, no. 19 (2021): 5849. http://dx.doi.org/10.3390/molecules26195849.

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Sesame seeds are rich in lignan content and have been well-known for their health benefits. Unlike the other sesame lignan compounds (i.e., sesamin and sesamol), the study of the pharmacological activity of sesamolin has not been explored widely. This review, therefore, summarizes the information related to sesamolin’s pharmacological activities, and the mechanism of action. Moreover, the influence of its physicochemical properties on pharmacological activity is also discussed. Sesamolin possessed neuroprotective activity against hypoxia-induced reactive oxygen species (ROS) and oxidative stre
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3

Anna, Belinska, Bochkarev Sergiy, Varankina Oleksandra, et al. "RESEARCH ON OXIDATIVE STABILITY OF PROTEIN-FAT MIXTURE BASED ON SESAME AND FLAX SEEDS FOR USE IN HALVA TECHNOLOGY." Eastern-European Journal of Enterprise Technologies 5, no. 11 (101) (2019): 6–14. https://doi.org/10.15587/1729-4061.2019.178908.

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The analysis of the main methods of modeling the formulations of protein-fat mixtures for special purposes has been conducted. Considerable attention is paid to the choice of methods for stabilizing their lipid component from oxidative damage. The urgency of increasing the oxidative stability of the protein-fat mixtures due to natural antioxidants is emphasized. The feasibility of comprehensive studies of their effect on the stability to oxidation of the most labile biologically active substances of protein-fat mixtures is substantiated. The content of furan antioxidants in the sesame seeds of
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4

Lim, Jin Seon, Yoshikazu Adachi, Yoko Takahashi, and Takashi Ide. "Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats." British Journal of Nutrition 97, no. 1 (2007): 85–95. http://dx.doi.org/10.1017/s0007114507252699.

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Effects of sesamin and sesamolin (sesame lignans) on hepatic fatty acid metabolism were compared in rats. Rats were fed either a lignan-free diet, a diet containing 0·6 or 2 g/kg lignan (sesamin or sesamolin), or a diet containing both sesamin (1·4 g/kg) and sesamolin (0·6 g/kg), for 10 d. Sesamin and sesamolin dose-dependently increased the activity and mRNA abundance of various enzymes involved in hepatic fatty acid oxidation. The increase was much greater with sesamolin than with sesamin. These lignans increased parameters of hepatic fatty acid oxidation in an additive manner when added sim
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5

Wan, Yuan, Qiaoyun Zhou, Mengge Zhao, and Tao Hou. "Byproducts of Sesame Oil Extraction: Composition, Function, and Comprehensive Utilization." Foods 12, no. 12 (2023): 2383. http://dx.doi.org/10.3390/foods12122383.

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Sesame is principally used to generate oil, which is produced by chemical refining or pressing. Sesame meal, as a main byproduct of sesame oil extraction, is usually discarded, causing resource waste and economic loss. Sesame meal is rich in sesame protein and three types of sesame lignans (sesamin, sesamolin, and sesamol). Sesame protein extracted via a physical method and an enzymic method has balanced amino acid composition and is an important protein source, and thus it is often added to animal feed and used as a human dietary supplement. Extracted sesame lignan exhibits multiple biologica
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6

Yu, Jing, Hao Sun, Yang Yang, and Yaping Yan. "Sesamolin Alleviates Nonalcoholic Fatty Liver Disease through Modulating Gut Microbiota and Metabolites in High-Fat and High-Fructose Diet-Fed Mice." International Journal of Molecular Sciences 23, no. 22 (2022): 13853. http://dx.doi.org/10.3390/ijms232213853.

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Nonalcoholic fatty liver disease (NAFLD) has become a major public health problem. The effects of sesamolin on obesity-associated NAFLD and its possible mechanism are still poorly understood. The present study investigated the effects of sesamolin on NAFLD and changes in gut microbiota and serum metabolites in high-fat and high-fructose (HF-HF) diet-fed mice. Mice with NAFLD were treated with or without sesamolin. Sesamolin effectively suppressed obesity-associated metabolic disorder, attenuated hepatic steatosis and the infiltration of inflammatory cells, and decreased levels of hepatic proin
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7

Baek, Seung-Hwa, Myung-Gyun Kang, and Daeui Park. "Inhibitory Effect of Sesamolin on Melanogenesis in B16F10 Cells Determined by In Vitro and Molecular Docking Analyses." Current Pharmaceutical Biotechnology 21, no. 2 (2020): 169–78. http://dx.doi.org/10.2174/1389201020666191011151123.

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Background: Melanin protects the skin against the harmful effects of ultraviolet irradiation. However, melanin overproduction can result in several aesthetic problems, including melasma, freckles, age spots and chloasma. Therefore, development of anti-melanogenic agents is important for the prevention of serious hyperpigmentation diseases. Sesamolin is a lignan compound isolated from sesame seeds with several beneficial properties, including potential for melanin inhibition. Objective: The aim of this study was to evaluate the anti-melanogenic effect of sesamolin in cell culture in vitro and t
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8

Hadeel, S. Y., S. A. Khalida, and Marie Walsh. "Antioxidant activity of sesame seed lignans in sunflower and flaxseed oils." Food Research 4, no. 3 (2019): 612–22. http://dx.doi.org/10.26656/fr.2017.4(3).331.

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This study investigated the antioxidant activity of crude lignan extracts and purified lignans (sesamin, sesamolin, and sesamol) in sunflower and flaxseed oils. Lignan extracts were prepared from roasted sesame seed oil (LRSO) and unroasted sesame seed oil (LUSO). Additionally, the individual lignans were purified from both oils. The crude extracts and purified lignans were added at concentrations of 0.01, 0.02 and 0.03% to the oils and stored at 25 and 65°C over time and peroxide values and thiobarbituric acid values were measured. Each oil showed an increase in oxidation over time, with the
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9

Tzen, Jason T. C., Fu-Chou Cheng, Tzyy-Rong Jinn, and Rolis C. W. Hou. "Neuroprotective Effects of Sesamin and Sesamolin on Gerbil Brain in Cerebral Ischemia." International Journal of Biomedical Science 2, no. 3 (2006): 284–88. http://dx.doi.org/10.59566/ijbs.2006.2284.

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Sesamin and sesamolin, abundant lignans found in sesame oil, have been demonstrated to possess several bioactivities beneficial for human health. Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated when they were pretreated with sesamin or sesamolin. The neuroprotective effect of sesamin and sesamolin was also observed in vivo using gerbils subjected to a focal cerebral ischemia induced by occlusion of the right common carotid artery and the right middle cerebral artery. Repeated treatment of sesamin or a crude sesame oil
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10

Xu, Fangtao, Rong Zhou, Senouwa Segla Koffi Dossou, Shengnan Song, and Linhai Wang. "Fine Mapping of a Major Pleiotropic QTL Associated with Sesamin and Sesamolin Variation in Sesame (Sesamum indicum L.)." Plants 10, no. 7 (2021): 1343. http://dx.doi.org/10.3390/plants10071343.

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Deciphering the genetic basis of quantitative agronomic traits is a prerequisite for their improvement. Herein, we identified loci governing the main sesame lignans, sesamin and sesamolin variation in a recombinant inbred lines (RILs, F8) population under two environments. The content of the two lignans in the seeds was investigated by HPLC. The sesamin and sesamolin contents ranged from 0.33 to 7.52 mg/g and 0.36 to 2.70 mg/g, respectively. In total, we revealed 26 QTLs on a linkage map comprising 424 SSR markers, including 16 and 10 loci associated with sesamin and sesamolin variation, respe
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11

Matsumura, Shinichi, Kazuya Murata, Nobuhiro Zaima та ін. "Inhibitory Activities of Sesame Seed Extract and its Constituents against β-Secretase". Natural Product Communications 11, № 11 (2016): 1934578X1601101. http://dx.doi.org/10.1177/1934578x1601101112.

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The need for a preventive agent against dementia led us to screen natural plant resources. Among the herbs and spices tested, sesame seed prepared from Sesamum indicum seeds showed potent β-secretase inhibitory activity. The active principles were determined to be sesamin and sesamolin, typical lignans in S. indicum. The IC50 values of sesamin and sesamolin were 257 and 140 μM, respectively. These compounds were investigated in a preliminary absorption experiment. After oral administration, these compounds were detected in an intact form in the brain and serum. These results suggest that consu
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12

Junhom, C., B. Siriwarin, N. Weerapreeyakul, and S. Barusrux. "210: Effect of sesamin, sesamolin and sesamol on P-glycoprotein mediated efflux." European Journal of Cancer 50 (July 2014): S48. http://dx.doi.org/10.1016/s0959-8049(14)50181-5.

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13

Srisayam, Montra, Natthida Weerapreeyakul, and Kwanjai Kanokmedhakul. "Inhibition of two stages of melanin synthesis by sesamol, sesamin and sesamolin." Asian Pacific Journal of Tropical Biomedicine 7, no. 10 (2017): 886–95. http://dx.doi.org/10.1016/j.apjtb.2017.09.013.

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14

Hofer, Otmar, Gerda Lutz, Günter Brader, and Christoph Kratky. "Conformational Analysis of Tetrahydrofurofuran Lignans: Sesamolin." HETEROCYCLES 45, no. 2 (1997): 287. http://dx.doi.org/10.3987/com-96-7651.

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15

Jeng, K., and R. Hou. "Sesamin and Sesamolin: Natures Therapeutic Lignans." Current Enzyme Inhibition 1, no. 1 (2005): 11–20. http://dx.doi.org/10.2174/1573408052952748.

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16

Salamah, Nina. "Identify the Purity of Sesame Oil from Sesame Seeds (Sesamum indicum L.) and Analysis Using the ATR-FTIR Method." Indonesian Journal of Pharmaceutical Science and Technology 11, no. 3 (2024): 382–92. http://dx.doi.org/10.24198/ijpst.v11i3.50102.

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Sesame seeds (Sesamum indicum L.) are a plant that produces the most important and oldest oil known to man. Apart from being rich in nutrients, sesame consists of important functional components such as sesamin, sesamolin, sesamol, sesaminol, sesamolin phenol, and other lignan-like active ingredients and can trigger the motive to produce sesame oil by adulteration in order to achieve market desires. The aim of this research is to identify the purity of sesame oil and analyze it using the ATR-FTIR method to detect and prevent counterfeiting. Testing the characteristics of sesame oil can be adju
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17

Shah, Hayder Ali, Ajay Kumar Tikoo, and Sabiha Khan. "Phytochemical and Ethnopharmacological Review of Till Safeed (Sesamum indicum Linn.)." Journal of Drug Delivery and Therapeutics 14, no. 9 (2024): 223–31. http://dx.doi.org/10.22270/jddt.v14i9.6803.

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Within the management of health care, the traditional system of medicine remains indispensable. The Unani system of medicine treats a variety of illnesses with a range of medications derived from plants. Historically, people have utilized sesamum indicum seeds as a medicinal ingredient. Various parts of the plant have been used by traditional physicians. However, the dried seed and oil are commonly used as Till in Unani Medicine. The plant has a very long history of use as a medicinal herb. It can be used on its own or in compound pharmacopeial compositions with other medications. Till Safeed
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18

Kurt, Cemal. "Susamın (Sesamum indicum) Sağlık Üzerine Bazı Etkileri." Turkish Journal of Agriculture - Food Science and Technology 12, no. 7 (2024): 1231–37. http://dx.doi.org/10.24925/turjaf.v12i7.1231-1237.6241.

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Zengin bir protein kaynağı olan susam, yağ elde etmek amacıyla yetiştirilen ilk bitkilerden biridir ve dünyanın birçok ülkesinde tarih öncesi çağlardan beri kültürü yapılmaktadır. Susam tohumları yüksek oranda içerdiği yağ asitlerinin (ortalama %80) doymamış yanı sıra insan sağlığı için önemli faydaları olan sesamol ve sesamolin gibi antioksidanları da içermektedir. Ayrıca tohumları önemli bir Ca, Mg ve Se kaynağıdır. Son yıllarda yapılan çalışmalar, susam tohumları ve yağının insan beslenmesi için yüksek enerji kaynağı olmasının yanı sıra insan sağlığı açısından da anti-aging, antikanserojen,
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19

Bedigian, Dorothea, David S. Seigler, and Jack R. Harlan. "Sesamin, sesamolin and the origin of sesame." Biochemical Systematics and Ecology 13, no. 2 (1985): 133–39. http://dx.doi.org/10.1016/0305-1978(85)90071-7.

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20

Liu, Ling-shuai, Yu-meng Yu, Chen-xia Zhang, et al. "Acid-catalyzed conversion of sesamolin to sesamol: Kinetics and reaction mechanism based on density functional theory." Food Chemistry 472 (April 2025): 142972. https://doi.org/10.1016/j.foodchem.2025.142972.

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21

Andargie, Mebeaselassie, Maria Vinas, Anna Rathgeb, Evelyn Möller, and Petr Karlovsky. "Lignans of Sesame (Sesamum indicum L.): A Comprehensive Review." Molecules 26, no. 4 (2021): 883. http://dx.doi.org/10.3390/molecules26040883.

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Major lignans of sesame sesamin and sesamolin are benzodioxol--substituted furofurans. Sesamol, sesaminol, its epimers, and episesamin are transformation products found in processed products. Synthetic routes to all lignans are known but only sesamol is synthesized industrially. Biosynthesis of furofuran lignans begins with the dimerization of coniferyl alcohol, followed by the formation of dioxoles, oxidation, and glycosylation. Most genes of the lignan pathway in sesame have been identified but the inheritance of lignan content is poorly understood. Health-promoting properties make lignans a
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22

LUTZ, G., O. HOFER, G. BRADER, and C. KRATKY. "ChemInform Abstract: Conformational Analysis of Tetrahydrofurofuran Lignans: Sesamolin." ChemInform 28, no. 34 (2010): no. http://dx.doi.org/10.1002/chin.199734276.

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23

Wu, Ming-Shun, Levent Bless B. Aquino, Marjette Ylreb U. Barbaza, et al. "Anti-Inflammatory and Anticancer Properties of Bioactive Compounds from Sesamum indicum L.—A Review." Molecules 24, no. 24 (2019): 4426. http://dx.doi.org/10.3390/molecules24244426.

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The use of foodstuff as natural medicines has already been established through studies demonstrating the pharmacological activities that they exhibit. Knowing the nutritional and pharmacological significance of foods enables the understanding of their role against several diseases. Among the foods that can potentially be considered as medicine, is sesame or Sesamum indicum L., which is part of the Pedaliaceae family and is composed of its lignans such as sesamin, sesamol, sesaminol and sesamolin. Its lignans have been widely studied and are known to possess antiaging, anticancer, antidiabetes,
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24

Bożek, Małgorzata, Julia Trybała, Agata Lebiedowska, Anna Stolecka-Warzecha, Paula Babczyńska, and Sławomir Wilczyński. "Assessment of the Sunscreen Properties of Sesame Oil Using the Hemispherical Directional Reflectance Method." Applied Sciences 14, no. 15 (2024): 6545. http://dx.doi.org/10.3390/app14156545.

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Sesame oil has been widely used for centuries. It is not only used as a kitchen ingredient, but it is also used to apply to the skin. Sesame oil contains natural compounds such as sesamol, sesamolin and sesamide, which have the ability to reflect or absorb certain UV rays. These substances can act as UV filters, helping to minimize the effects of harmful UV radiation on the skin. The aim of the study was to investigate the radioprotective/sun protection properties of sesame oil. The influence of sesame oils from different manufacturers on the directional reflectance of the skin was analyzed at
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Kitipaspallop, Wannakarn, Siwapech Sillapaprayoon, Preecha Phuwapraisirisan, Woo-Keun Kim, Chanpen Chanchao, and Wittaya Pimtong. "Developmental effects of sesamolin on zebrafish (Danio rerio) embryos." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 256 (June 2022): 109319. http://dx.doi.org/10.1016/j.cbpc.2022.109319.

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26

Kang, Myung-Hwa, Michitaka Naito, Nobuko Tsujihara, and Toshihiko Osawa. "Sesamolin Inhibits Lipid Peroxidation in Rat Liver and Kidney." Journal of Nutrition 128, no. 6 (1998): 1018–22. http://dx.doi.org/10.1093/jn/128.6.1018.

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27

Srisongkram, Tarapong, and Natthida Weerapreeyakul. "Route of intracellular uptake and cytotoxicity of sesamol, sesamin, and sesamolin in human melanoma SK-MEL-2 cells." Biomedicine & Pharmacotherapy 146 (February 2022): 112528. http://dx.doi.org/10.1016/j.biopha.2021.112528.

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28

Lee, Jinyoung, Yoosung Lee, and Eunok Choe. "Effects of sesamol, sesamin, and sesamolin extracted from roasted sesame oil on the thermal oxidation of methyl linoleate." LWT - Food Science and Technology 41, no. 10 (2008): 1871–75. http://dx.doi.org/10.1016/j.lwt.2007.11.019.

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29

Shin, Bo Ram, Seung-Ok Yang, Hye-Won Song, Myung-Sub Chung, and Young-Suk Kim. "Effects of adsorbents on benzo(a)pyrene, sesamol, and sesamolin contents and volatile component profiles in sesame oil." Food Science and Biotechnology 24, no. 6 (2015): 2017–22. http://dx.doi.org/10.1007/s10068-015-0266-x.

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30

Yuenyong, Jitkunya, Suchintana Limkoey, Chonlathit Phuksuk, et al. "Enhancing Functional Compounds in Sesame Oil through Acid-Soaking and Microwave-Heating of Sesame Seeds." Foods 13, no. 18 (2024): 2891. http://dx.doi.org/10.3390/foods13182891.

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This study investigated whether pre-treating sesame (Sesamum indicum L.) seeds with a combination of acid-soaking and microwave-heating could significantly enhance the quality of the resulting sesame oil, particularly by increasing its content of functional compounds such as lignans, tocopherol, phytosterol, and squalene. The study revealed that soaking the sesame seeds in a solution of HCl and citric acid, along with microwave-heating, significantly increased the content of these compounds. The detected ranges were sesamin (1365–6927 µg g−1), sesamolin (605–3493 µg g−1), tocopherol (69.31–282
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Chantzos, Nickolaos, and Constantinos Georgiou. "Monitoring lipid oxidation events at frying temperatures through radical scavenging assays." Chemical Industry and Chemical Engineering Quarterly 13, no. 3 (2007): 163–66. http://dx.doi.org/10.2298/ciceq0703163c.

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This communication proposes an alternative approach for monitoring oils during thermal stress at frying temperatures through radical scavenging assays. Oxidation events for extra virgin olive, pomace, sesame, sunflower, soybean, corn and of a commercial blend of oils are followed through the DPPH assay during heating at 100, 150 and 190?C. Radical scavenging activity decrease expressed as trolox equivalent antioxidant capacity (?TEAC, mmol trolox kg-1 oil) is found to be linearly related to increases in total oxidation (?TOTOX) values. This relationship is valid down to a certain - ?TEAC value
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Kandalkar, Ankita, Anushka Dinesh, and Sagar Nagare. "Identification of Potent Natural Inhibitor Against Papain Like Protease of SARS CoV 2 an in Silico Approach." Defence Life Science Journal 8, no. 1 (2023): 41–49. http://dx.doi.org/10.14429/dlsj.8.17831.

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One of the most complicated tasks the healthcare system has faced in recent years has been the development of a curative treatment to stop the progression of the SARS CoV-2 virus. No consensus has been reached on a medical cure to slow the virus spread. From this point of view, investigating existing drugs such as SARS-CoV-2 inhibitors is an appropriate technique. With critical involvement in viral replication and host-immune suppression, Papain-like protease (PL-pro) is recognized as a key enzyme target for drug development among other SARS-CoV-2 druggable targets. Phytolignans have a wide ra
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Kim, A.-Young, Choong-In Yun, Joon-Goo Lee, and Young-Jun Kim. "Determination and Daily Intake Estimation of Lignans in Sesame Seeds and Sesame Oil Products in Korea." Foods 9, no. 4 (2020): 394. http://dx.doi.org/10.3390/foods9040394.

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Sesame (Sesamum indicum L.) is a plant that belongs to the Pedaliaceae family which was first classified as a food source around 4000 years ago. Lignans (sesamin, sesamolin, sesamol, and sesaminol) present in sesame are the primary functional compounds that impart important health benefits. However, very little information is available on the lignan intake from sesame seeds and sesame oil products. Sesame oil is frequently and highly consumed in Korea and therefore is one of the important lignan intake sources due to the food eating habits of Koreans. Herein, we studied the distribution of lig
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Muangrat, Rattana, Yongyut Chalermchart, Supachet Pannasai, and Sukhuntha Osiriphun. "Effect of Roasting and Vacuum Microwave Treatments on Physicochemical and Antioxidant Properties of Oil Extracted from Black Sesame Seeds." Current Research in Nutrition and Food Science Journal 8, no. 3 (2020): 798–814. http://dx.doi.org/10.12944/crnfsj.8.3.12.

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Unroasted, roasted (at roasting temperatures of 100, 150 and 200 C and roasting times of 10, 20 and 30 min) and vacuum microwaved (at microwave watt powers of 800, 1440, 2400 and 3600 watts/kg black sesame seeds, for heating times of 10, 20 and 30 min) black sesame seeds were processed to extract oil using a single screw press at a constant pressing temperature of 50 C. The results revealed that different heat pre-treatments significantly affected yield and physiochemical and antioxidant properties of extracted oils. The extracted oil samples exhibited significantly different levels of total
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NAGATA, Masayasu, Toshihiko OSAWA, Mitsuo NAMIKI, Yasuko FUKUDA, and Tatsuhiko OZAKI. "Stereochemical structures of antioxidative bisepoxylignans, sesaminol and its isomers, transformed from sesamolin." Agricultural and Biological Chemistry 51, no. 5 (1987): 1285–89. http://dx.doi.org/10.1271/bbb1961.51.1285.

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Nagata, Masayasu, Toshihiko Osawa, Mitsuo Namiki, Yasuko Fukuda, and Tatsuhiko Ozaki. "Stereochemical Structures of Antioxidative Bisepoxylignans, Sesaminol and Its Isomers, Transformed from Sesamolin." Agricultural and Biological Chemistry 51, no. 5 (1987): 1285–89. http://dx.doi.org/10.1080/00021369.1987.10868187.

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37

Liang, Ming-Tsai, Ru-Chien Liang, Li-Rong Huang, Ping-Hsuan Hsu, Yu-Hsuan Wu, and Hung-En Yen. "Separation of Sesamin and Sesamolin by a Supercritical Fluid-Simulated Moving Bed." American Journal of Analytical Chemistry 03, no. 12 (2012): 931–38. http://dx.doi.org/10.4236/ajac.2012.312a123.

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38

Keowkase, Roongpetch, Natthawut Shoomarom, Worawee Bunargin, Worapan Sitthithaworn та Natthida Weerapreeyakul. "Sesamin and sesamolin reduce amyloid-β toxicity in a transgenic Caenorhabditis elegans". Biomedicine & Pharmacotherapy 107 (листопад 2018): 656–64. http://dx.doi.org/10.1016/j.biopha.2018.08.037.

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Hou, Rolis Chien-Wei, Hsueh-Meei Huang, Jason T. C. Tzen, and Kee-Ching G. Jeng. "Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells." Journal of Neuroscience Research 74, no. 1 (2003): 123–33. http://dx.doi.org/10.1002/jnr.10749.

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40

Huang, Jinian, Guohui Song, Lixia Zhang, Qiang Sun, and Xin Lu. "A novel conversion of sesamolin to sesaminol by acidic cation exchange resin." European Journal of Lipid Science and Technology 114, no. 7 (2012): 842–48. http://dx.doi.org/10.1002/ejlt.201100247.

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Jan, Kuo-Ching, and Mohsen Gavahian. "Sustainable Supercritical Carbon Dioxide Extraction of Value-Added Lignan from Sesame Meal: Achieving Green Neuroprotection and Waste Valorization by Optimizing Temperature, Solvent, and Pressure." Molecules 30, no. 3 (2025): 539. https://doi.org/10.3390/molecules30030539.

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In pursuing sustainable health solutions and growing demand for neuroprotective interventions, the industry demands alternative green extraction technologies to valorize agri-food by-products. This study aimed to develop an optimized supercritical carbon dioxide extraction to isolate sesame meal’s functional compound (lignans) and assess their neuroprotective effects. Extraction was performed at various pressures (2–4 kpsi), temperatures (40–60 °C), co-solvent concentrations (2–25 mol% ethanol), and CO2 collection segments (0–100 NL) to systematically analyze extraction parameters. Extracts we
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Shin, Bo Ram, Hye-Won Song, Joon-Goo Lee, Hae-Jung Yoon, Myung-Sub Chung, and Young-Suk Kim. "Comparison of the contents of benzo(a)pyrene, sesamol and sesamolin, and volatiles in sesame oils according to origins of sesame seeds." Applied Biological Chemistry 59, no. 1 (2016): 129–41. http://dx.doi.org/10.1007/s13765-015-0138-3.

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Takahashi, Miki, Yuzo Nishizaki, Koji Morimoto, Naoki Sugimoto, Kyoko Sato, and Koichi Inoue. "Design of synthetic single reference standards for the simultaneous determination of sesamin, sesamolin, episesamin, and sesamol by HPLC using relative molar sensitivity." Separation Science Plus 1, no. 7 (2018): 498–505. http://dx.doi.org/10.1002/sscp.201800081.

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OZAYDİN, Dilan, and Pınar KURU BEKTAŞOĞLU. "Travmatik Beyin Hasarı Sıçan Modelinde Sesamol’ün İkincil Yaralanmaya Karşı Koruyucu Etkileri." Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 25, no. 1 (2023): 136–42. http://dx.doi.org/10.24938/kutfd.1262700.

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Amaç: Sesamol güçlü bir antioksidan, antiinflammatuar, antiapoptotik ve nöroprotektif bir kimyasaldır. Bu çalışmada, sesamolün sıçan travmatik beyin hasarı (TBH) modelinde histopatolojik etkilerinin araştırılması amaçlanmıştır.
 
 Gereç ve Yöntemler: Otuz iki erkek sıçan dört gruba ayrıldı: kontrol, travma, sham ve sesamol. Travma, sham ve sesamol gruplarına ağırlık düşme yöntemi ile kapalı kafa travması uygulandı, travmadan hemen sonra sırasıyla sham ve sesamol gruplarına periton içine salin ve sesamol (100 mg/kg) uygulandı. Travmadan 24 saat sonra, beyin örnekleri alındı ve elektro
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Fukuda, Yasuko, Minoru Isobe, Masayasu Nagata, Toshihiko Owaea, and Mitsuo Namiki. "Acidic Transformation of Sesamolin, the Sesami-oil Constituent, into an Antioxidant Bisepoxylignan, Sesaminol." HETEROCYCLES 24, no. 4 (1986): 923. http://dx.doi.org/10.3987/r-1986-04-0923.

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Tsai, Hsin-Ya, Wei-Ju Lee, I.-Hsuan Chu, Wei-Ching Hung, and Nan-Wei Su. "Formation of Samin Diastereomers by Acid-Catalyzed Transformation of Sesamolin with Hydrogen Peroxide." Journal of Agricultural and Food Chemistry 68, no. 23 (2020): 6430–38. http://dx.doi.org/10.1021/acs.jafc.0c01616.

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AMAROWICZ, R., F. SHAHIDI, and R. B. PEGG. "APPLICATION OF SEMIPREPARATIVE RP-18 HPLC FOR THE PURIFICATION OF SESAMIN AND SESAMOLIN." Journal of Food Lipids 8, no. 2 (2001): 85–94. http://dx.doi.org/10.1111/j.1745-4522.2001.tb00186.x.

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Lee, Jae Kwon. "Sesamolin promotes cytolysis and migration activity of natural killer cells via dendritic cells." Archives of Pharmacal Research 43, no. 4 (2020): 462–74. http://dx.doi.org/10.1007/s12272-020-01229-y.

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Dehkordi, Farshad Roghani, and Mehrdad Roghani. "Mechanisms Underlying Sesamolin-Induced Attenuation of Vascular Dysfunction in Rats With Streptozotocin-Induced Diabetes." International Journal of Endocrinology & Metabolism 9, no. 2 (2012): 311–16. http://dx.doi.org/10.5812/kowsar.1726913x.2380.

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FUKUDA, Yasuko, Toshihiko OSAWA, Shunro KAWAGISHI, and Mitsuo NAMIKI. "Comparison of contents of sesamolin and lignan antioxidants in sesame seeds cultivated in Japan." NIPPON SHOKUHIN KOGYO GAKKAISHI 35, no. 7 (1988): 483–86. http://dx.doi.org/10.3136/nskkk1962.35.7_483.

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