Relevant bibliographies by topics / SETBP1

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'SETBP1'

Author: Grafiati
Published: 9 March 2023
Last updated: 31 July 2025

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Journal articles on the topic "SETBP1"

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Carlson, Hanqian L., Samantha Tauchmann, Thai Nguyen, et al. "SETBP1 Regulates Myst Acetyltransferase Complexes to Drive a Leukemogenic Gene Expression Program." Blood 144, Supplement 1 (2024): 3143. https://doi.org/10.1182/blood-2024-203971.

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Mutations in set binding protein 1 (SETBP1) are frequent in non-classical myeloproliferative disorders and are strongly associated with adverse prognosis. SETBP1 mutations are found in ~45% of chronic neutrophilic leukemia, 24% of atypical chronic myeloid leukemia, 4-15% of chronic myelomonocytic leukemia, and ~30% of juvenile myelomonocytic leukemia cases. Despite strong prognostic significance, we lack a comprehensive understanding of the oncogenic mechanism of SETBP1 mutations and have no therapies that target them. SETBP1 is a nuclear protein that interacts with chromatin. SETBP1 mutations
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Nguyen, Nhu, Kristbjorn Orri Gudmundsson, Anthony R. Soltis, et al. "Recruitment of MLL1 Complex Is Essential for SETBP1 to Induce Myeloid Transformation." Blood 138, Supplement 1 (2021): 1147. http://dx.doi.org/10.1182/blood-2021-152825.

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Abstract Abnormal activation of SETBP1 due to overexpression or missense mutations occurs frequently in various myeloid neoplasms and associates with poor prognosis. Direct activation of Hoxa9/Hoxa10/Myb transcription by SETBP1 and its missense mutants is essential for their transforming capability; however, the underlying mechanisms for such activation remain elusive. We found that knockdown of Mll1 in mouse myeloid progenitors immortalized by SETBP1 or its missense mutant SETBP1(D/N) caused significant reduction in the mRNA levels of Hoxa9/Hoxa10/Myb, suggesting that Mll1 is critical for the
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Pacharne, Suruchi, Oliver M. Dovey, Jonathan L. Cooper, et al. "SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD–mutant AML." Blood Advances 5, no. 9 (2021): 2412–25. http://dx.doi.org/10.1182/bloodadvances.2020003443.

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Abstract Advances in cancer genomics have revealed genomic classes of acute myeloid leukemia (AML) characterized by class-defining mutations, such as chimeric fusion genes or in genes such as NPM1, MLL, and CEBPA. These class-defining mutations frequently synergize with internal tandem duplications in FLT3 (FLT3-ITDs) to drive leukemogenesis. However, ∼20% of FLT3-ITD–positive AMLs bare no class-defining mutations, and mechanisms of leukemic transformation in these cases are unknown. To identify pathways that drive FLT3-ITD mutant AML in the absence of class-defining mutations, we performed an
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Yang, Jingyi, Shanlan Mo, Xudong Wei, et al. "Heritable SETBP1 Mutations Associated with Myelodysplastic Syndrome and Acute Myeloid Leukemia." Blood 142, Supplement 1 (2023): 5684. http://dx.doi.org/10.1182/blood-2023-182788.

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Introduction The SET binding protein 1 (SETBP1) gene is an oncogene located on chromosome 18q12.3, which is related to DNA replication and gene transcription regulation. Variants in SETBP1 are involved in germline and somatic mutations, leading to extremely different pathologic consequences. Germline mutations in SETBP1 are associated with Schinzel-Giedion syndrome (SGS) and SETBP1 Haploinsufficiency Disorder. In contrast, somatic mutations in SETBP1 are linked with myeloid malignancies and clonal hematopoiesis. The vast majority of reported germline SETBP1 mutations were located in the SKI ho
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Kawashima, Nozomu, Yusuke Okuno, Yuko Sekiya, et al. "Generation of Cell Lines Harboring SETBP1 Mutations By the Crispr/Cas9 System." Blood 124, no. 21 (2014): 4622. http://dx.doi.org/10.1182/blood.v124.21.4622.4622.

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Abstract Introduction Recent advances in cancer genetics have led to the identification of somatic mutations in SET-binding protein 1 (SETBP1) in myeloid malignancies categorized as myeloproliferative neoplasm (MPN) and myelodysplastic syndromes (MDS). Heterozygous point mutations in SETBP1 are essentially found at a genomic level in myeloid malignancies, and the frequency of the mutated allele in cDNA suggests somatic heterozygosity without substantial imbalance in allelic expression. Thus, mutant SETBP1 presumably has a dominant altered biological activity. Most mutations in SETBP1 are locat
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Crespiatico, Ilaria, Mattia Zaghi, Cristina Mastini, et al. "First-hit SETBP1 mutations cause a myeloproliferative disorder with bone marrow fibrosis." Blood 143, no. 14 (2024): 1399–413. http://dx.doi.org/10.1182/blood.2023021349.

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Abstract SETBP1 mutations are found in various clonal myeloid disorders. However, it is unclear whether they can initiate leukemia, because SETBP1 mutations typically appear as later events during oncogenesis. To answer this question, we generated a mouse model expressing mutated SETBP1 in hematopoietic tissue: this model showed profound alterations in the differentiation program of hematopoietic progenitors and developed a myeloid neoplasm with megakaryocytic dysplasia, splenomegaly, and bone marrow fibrosis, prompting us to investigate SETBP1 mutations in a cohort of 36 triple-negative prima
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Pacharne, Suruchi, Oliver M. Dovey, Jonathan L. Cooper, et al. "Setbp1 Overexpression Acts in the Place of Class-Defining Somatic Mutations to Drive Mouse and Human FLT3-ITD-Mutant AMLs." Blood 136, Supplement 1 (2020): 31–32. http://dx.doi.org/10.1182/blood-2020-141743.

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Setbp1 overexpression acts in the place of class-defining somatic mutations to drive mouse and human FLT3-ITD-mutant AMLs Suruchi Pacharne,1,2 Oliver M. Dovey,1 Jonathan L. Cooper,1 Muxin Gu,1,2 MS Vijaybaskar,1,2 Mathias J. Friedrich,1,5 Malgorzata Gozdecka,1,2 Sandeep S. Rajan,1,4, Etienne De Braekeleer,1,2 Maxim Barenboim,5,6 Grace Collord,1,2 Hannes Ponstingl,1 Ruben Bautista,1 Milena Mazan,1,8 Roland Rad,5,6 Konstantinos Tzelepis,1,7 Penny Wright,3 and George S. Vassiliou1,2,9* Abstract Internal tandem duplications in FLT3 (FLT3-ITD) are found in 30% of acute myeloid leukemia (AML) cases
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Oakley, Kevin, Yufen Han, Bandana A. Vishwakarma, et al. "Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10." Blood 119, no. 25 (2012): 6099–108. http://dx.doi.org/10.1182/blood-2011-10-388710.

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Abstract Acquisition of self-renewal capability by myeloid progenitors to become leukemic stem cells during myeloid leukemia development is poorly understood. Here, we show that Setbp1 overexpression efficiently confers self-renewal capability to myeloid progenitors in vitro, causing their immortalization in the presence of stem cell factor and IL-3. Self-renewal after immortalization requires continuous Setbp1 expression. We also found that Hoxa9 and Hoxa10 mRNA are present at dramatically higher levels in Setbp1-immortalized cells compared with other immortalized cells, and are induced short
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Whitlock, Jordan H., Elizabeth J. Wilk, Timothy C. Howton, Amanda D. Clark, and Brittany N. Lasseigne. "The landscape of SETBP1 gene expression and transcription factor activity across human tissues." PLOS ONE 19, no. 1 (2024): e0296328. http://dx.doi.org/10.1371/journal.pone.0296328.

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The SET binding protein 1 (SETBP1) gene encodes a transcription factor (TF) involved in various cellular processes. Variants in SETBP1 can result in three different diseases determined by the introduction (germline vs. somatic) and location of the variant. Germline variants cause the ultra-rare pediatric Schinzel Giedion Syndrome (SGS) and SETBP1 haploinsufficiency disorder (SETBP1-HD), characterized by severe multisystemic abnormalities with neurodegeneration or a less severe brain phenotype accompanied by hypotonia and strabismus, respectively. Somatic variants in SETBP1 are associated with
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Makishima, Hideki, Kenichi Yoshida, Nhu Nguyen, et al. "Somatic Mutations in Schinzel-Giedion Syndrome Gene SETBP1 Determine Progression in Myeloid Malignancies." Blood 120, no. 21 (2012): 2. http://dx.doi.org/10.1182/blood.v120.21.2.2.

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Abstract Abstract 2 MDS and other chronic myeloid malignancies such as MDS/MPN are characterized by a frequent progression to secondary AML (sAML), a likely multistep process of acquisition of genetic abnormalities. Genes involved in congenital genetic cancer susceptibility syndromes are often targets of somatic mutations in various tumors. For instance, germ-line mutations of SETBP1 are associated with Schinzel-Giedion syndrome (SGS), which is characterized by skeletal malformations, mental retardation and frequent neuroepithelial tumors. While SETBP1 overexpression in myeloid malignancies li
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Dissertations / Theses on the topic "SETBP1"

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VALLETTA, SIMONA. "Recurrent SETBP1 mutations in atypical chronic myeloid leukemia." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50227.

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Atypical chronic myeloid leukemia (aCML) is a heterogeneous disorder belonging to the group of myelodysplastic/myeloproliferative (MDS/MPN) syndromes. aCML shares clinical and laboratory features with Chronic Myeloid Leukemia (CML), but it lacks the Philadelphia chromosome and the resulting BCR-ABL fusion gene. This crucial difference with CML points to a different pathogenetic process. Because no specific recurrent genomic or karyotypic abnormalities have been identified in aCML, and the molecular pathogenesis of this disease has remained elusive with a dismal outcome, we performed exome-sequ
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PERONACI, MARCO. "Characterization of new oncogenes identified through NGS-based analysis of leukemias: SETBP1 and ETS2-ERG." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2017. http://hdl.handle.net/10281/144663.

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In the past years, the improvements in sequencing technology led to the development of “Next Generation Sequencing” (NGS) technologies. Several NGS approaches exist. Whole genome sequencing (WGS) and whole exome sequencing (WES) allow the identification of genomic alterations such as small insertions/deletions, point mutations and structural variants. Whole transcriptome sequencing (RNA-Seq) permits to quantify gene expression profiles and to detect alternative splicing and fusion transcripts. Recently, by using WES on atypical chronic myeloid leukemia (aCML) samples, our group identified recu
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KHANDELWAL, PRAVEEN. "Elucidating the oncogenic role of genetic events in BCR-ABL1 positive chronic myeloid leukemia." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2016. http://hdl.handle.net/10281/99449.

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In hematological myeloid malignancies the accumulation of oncogenic events plays a significant role in disease progression. Therefore, in this work, we studied (i) the mutational landscape in typical chronic myeloid leukemia (CML) patients and (ii) the neoplastic role of Setbp1 mutation in atypical chronic myeloid leukemia (aCML). 1) We evaluated somatic variants in CML patients by Next Generation Sequencing, to study the molecular pathogenesis of cancer. We conducted a mutational analysis on 23 chronic phase BCR-ABL1+ CML patients through exome and RNA sequencing performed on diagnosis samp
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Rediger, Daniel. "Minimizing production setups by optimizing the production setup." Connect to resource, 2006. http://hdl.handle.net/1811/6493.

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Thesis (Honors)--Ohio State University, 2006.<br>Title from first page of PDF file. Document formatted into pages: contains 9 p. Includes bibliographical references (p. ). Available online via Ohio State University's Knowledge Bank.
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Andersson, Joakim, and Jimmy Bertilsson. "SETUP TIME OPTIMIZATION." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-23661.

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Sammanfattning   Emhart Glass AB är världsledande företag inom glasflasktillverkning. De konstruerar automatiserade maskiner som formar glasflaskor. I Sverige finns det två fabriker, en i Örebro och en i Sundsvall. I Örebro tillverkar man främst reservdelar och nya delar till maskinerna medan man i Sundsvall monterar ihop maskinerna. Det finns totalt 15 olika fabriker och kontor över världen med huvudkontor i schweiziska Cham.      Eftersom Emhart Glass Örebro har för långa ställtider på några av deras maskiner ska det undersökas hur omställningsarbetet går till i dagsläget och hur omställning
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Bernardo, Heliudson de Oliveira. "Cosmological models from string theory setups /." São Paulo, 2019. http://hdl.handle.net/11449/183612.

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Orientador: Horatiu Nastase<br>Resumo: Nesta tese, discutimos três modelos cosmológicos que são baseados direta ou indiretamente em ideias advindas de teoria das cordas. Depois de uma revisão geral de cosmologia em teoria das cordas, um resumo de cosmologia e teoria das cordas é apresentado, com ênfase nos conceitos fundamentais e teóricos. Então descrevemos como o acoplamento camaleônico pode potencialmente afetar as predições de inflação cósmica com campo único, com tratamento cuidadoso dos modos de perturbação cosmológica adiabáticos e de entropia. Além disso uma nova abordagem para a duali
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Yang, Yanchun Bulfin Robert L. "Knapsack problems with setup." Auburn, Ala., 2006. http://repo.lib.auburn.edu/2006%20Summer/Dissertations/YANG_YANCHUN_31.pdf.

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Apotsos, Alex. "Setup in the surfzone." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/42219.

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Thesis (Ph. D.)--Joint Program in Applied Ocean Science and Engineering (Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering; and the Woods Hole Oceanographic Institution), 2007.<br>Includes bibliographical references.<br>Surfzone wave height transformation and wave-breaking-driven increases in the mean sea level (setup) are examined on alongshore-uniform beaches with alongshore homogeneous and inhomogeneous wave forcing. While previously derived models predict wave heights adequately (root-mean-square errors typically less than 20%), the models can be improved
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Yemm, Sean P. "Field Observation of setup." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2004. http://library.nps.navy.mil/uhtbin/hyperion/04Jun%5FYemm.pdf.

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Thesis (M.S. in Meteorology and Physical Oceanography)--Naval Postgraduate School, June 2004.<br>Thesis advisor(s): Edward Thornton. Includes bibliographical references (p. 29-31). Also available online.
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D'Uva, Michael. "Motor Generator Dynamometer Setup." Thesis, D'Uva, Michael (2013) Motor Generator Dynamometer Setup. Other thesis, Murdoch University, 2013. https://researchrepository.murdoch.edu.au/id/eprint/21902/.

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The primary aim of this thesis was the further development and reconstruction of the Motor Generator Dynamometer set up. Once completed, the apparatus is to be used as a learning tool for the engineering students at Murdoch University, demonstrating key concepts of electric machines and their reactions to the change in load conditions. For the mention primary aim the design, construction and commissioning of a load bank had to be adapted to the initial setup to enable the students to alter the connected load. Measurements and control of the apparatus was achieved through National instruments N
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Books on the topic "SETBP1"

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Earley, Fran. Setup. Harlequin Books, 1987.

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Earley, Fran. Setup. Harlequin Books, 1987.

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Mucha, Jiří. Spálená setba. 2nd ed. Eminent, 2001.

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Philippines. Department of Science and Technology. Setup success. Dept. of Science and Technology, 2011.

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Haidler, Jaroslav. Prokletá setba. Jota, 2011.

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Knight, Tim, ed. High-Probability Trade Setups. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781119202431.

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West, Roy. Setup and tutorials. NeXT Computer, 1991.

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Margaret, Watson. An unlikely setup. Harlequin, 2010.

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United States. Congress. Office of Compliance. Computer workstation setup. Office of Compliance, 2011.

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Fibonacci Price Cluster Setups: Trade Setup 1. McGraw-Hill, 2010.

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Book chapters on the topic "SETBP1"

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Hall, Christine M., Amaka C. Offiah, Francesca Forzano, Mario Lituania, Gen Nishimura, and Valérie Cormier-Daire. "Schinzel-Giedion Syndrome, SETBP1-Related." In Fetal and Perinatal Skeletal Dysplasias, 2nd ed. CRC Press, 2024. http://dx.doi.org/10.1201/9781003166948-140.

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Pütz, Ralph, and Ton Serné. "Vermessung des Setups Measurement of Setup." In Rennwagentechnik - Praxislehrgang Fahrdynamik. Springer Fachmedien Wiesbaden, 2017. http://dx.doi.org/10.1007/978-3-658-16102-6_1.

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Pütz, Ralph, and Ton Serné. "Vermessung des Setups Measurement of Setup." In Rennwagentechnik - Praxislehrgang Fahrdynamik. Springer Fachmedien Wiesbaden, 2019. http://dx.doi.org/10.1007/978-3-658-26704-9_1.

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Mohan, R. "1950–1967: One-Party Dominance in a Multi-Party Democracy." In India’s Federal Setup. Routledge, 2025. https://doi.org/10.4324/9781003615569-4.

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Mohan, R. "1967–71: An Interlude or the Beginning of a New Future?" In India’s Federal Setup. Routledge, 2025. https://doi.org/10.4324/9781003615569-5.

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Mohan, R. "The Way Ahead: What Can Be Envisioned." In India’s Federal Setup. Routledge, 2025. https://doi.org/10.4324/9781003615569-16.

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Mohan, R. "Five Questions on Federalism in India: What Does the Experience After Independence Reveal?" In India’s Federal Setup. Routledge, 2025. https://doi.org/10.4324/9781003615569-14.

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Mohan, R. "The 1990s: Changes in Politics and Economic Policy Shifts." In India’s Federal Setup. Routledge, 2025. https://doi.org/10.4324/9781003615569-9.

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Mohan, R. "Analysing the Evolving Trends." In India’s Federal Setup. Routledge, 2025. https://doi.org/10.4324/9781003615569-15.

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Mohan, R. "Political Actions and Their Impact on Federal Polity." In India’s Federal Setup. Routledge, 2025. https://doi.org/10.4324/9781003615569-11.

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Conference papers on the topic "SETBP1"

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Piazza, Rocco, Simona Valletta, Nils Winkelmann, et al. "Abstract 3176: Recurrent SETBP1 mutations in atypical chronic myeloid leukemia abrogate an ubiquitination site and dysregulate SETBP1 protein levels." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3176.

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Redaelli, Sara, Simona Valletta, Rocco Piazza, et al. "Abstract 2993: Patterns of recurrent mutations in SETBP1 mutated and wild-type atypical Chronic Myeloid Leukemia patients." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2993.

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Saito, Y., and K. Kobayashi. "Proposal of optical farming: development of several optical sensing instruments for agricultural use." In SPIE SeTBio, edited by Naoshi Kondo. SPIE, 2013. http://dx.doi.org/10.1117/12.2028830.

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Mat Nawi, Nazmi, Guangnan Chen, and Troy Jensen. "Application of visible and shortwave near infrared spectrometer to predict sugarcane quality from different sample forms." In SPIE SeTBio, edited by Naoshi Kondo. SPIE, 2013. http://dx.doi.org/10.1117/12.2029395.

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De Vylder, Jonas, Dominique Van Der Straeten, and Wilfried Philips. "Multiple leaf tracking using computer vision methods with shape constraints." In SPIE SeTBio, edited by Naoshi Kondo. SPIE, 2013. http://dx.doi.org/10.1117/12.2029789.

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Nguyen Do Trong, Nghia, Chyngyz Erkinbaev, Bart Nicolaï, Wouter Saeys, Mizuki Tsuta, and Josse De Baerdemaeker. "Spatially resolved spectroscopy for nondestructive quality measurements of Braeburn apples cultivated in sub-fertilization condition." In SPIE SeTBio, edited by Naoshi Kondo. SPIE, 2013. http://dx.doi.org/10.1117/12.2030407.

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Catalano, Pasquale, Flavio Fucci, Ferruccio Giametta, Giovanna La Fianza, and Biagio Bianchi. "Vibration analysis using a contactless acquisition system." In SPIE SeTBio, edited by Naoshi Kondo. SPIE, 2013. http://dx.doi.org/10.1117/12.2030414.

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Van Beers, Robbe, Ben Aernouts, Josse De Baerdemaeker, and Wouter Saeys. "Apple ripeness detection using hyperspectral laser scatter imaging." In SPIE SeTBio, edited by Naoshi Kondo. SPIE, 2013. http://dx.doi.org/10.1117/12.2030569.

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Kakinoki, Yoshiaki, Yuya Kato, Kosuke Ogawa, Akira Nakao, Zenshiro Okai, and Toshio Katsuyama. "Efficient plant growth using automatic position-feedback laser light irradiation." In SPIE SeTBio, edited by Naoshi Kondo. SPIE, 2013. http://dx.doi.org/10.1117/12.2030575.

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Sumriddetchkajorn, Sarun. "Mobile device-based optical instruments for agriculture." In SPIE SeTBio, edited by Naoshi Kondo. SPIE, 2013. http://dx.doi.org/10.1117/12.2030626.

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Reports on the topic "SETBP1"

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Milbrath, Brian, and Aviva Joy Sussman. Lufkin_Exercise_ Setup. Office of Scientific and Technical Information (OSTI), 2017. http://dx.doi.org/10.2172/1392855.

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Jean, Brian Altom. LANL problem setup. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1068931.

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Gillespie, L. K. Setup reduction approaches for machining. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/481589.

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Gardner, C. J. Booster Double Harmonic Setup Notes. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1172091.

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Grove, John W. Eulerian Applications Project - xRage Setup. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1607914.

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Rodgers, David E. Tritium calorimeter setup and operation. Office of Scientific and Technical Information (OSTI), 2002. http://dx.doi.org/10.2172/813568.

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Reid, Douglas J., Anthony D. Guzman, and John T. Munley. Majorana Thermosyphon Prototype Experimental Setup. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1025684.

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Frey, Lucille, and Guy Mcnamara. ASC Simulation-Setup Contour-File Specification. Office of Scientific and Technical Information (OSTI), 2014. http://dx.doi.org/10.2172/1164018.

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Andersson, L., R. Callon, R. Dantu, et al. Constraint-Based LSP Setup using LDP. Edited by B. Jamoussi. RFC Editor, 2002. http://dx.doi.org/10.17487/rfc3212.

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Yu, Ken F. Android Virtual Machine (VM) Setup on Linux. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada612920.

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