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Dissertations / Theses on the topic 'Severe acute malnutrition'

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1

Fergusson, Pamela Lynne. "Severe acute malnutrition and HIV in children in Malawi." Thesis, University of Chester, 2009. http://hdl.handle.net/10034/93477.

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Sub-Saharan Africa is more affected by the HIV epidemic than any other region of the world. At the same time, malnutrition remains a major public health concern. HIV and malnutrition are interlinked, both epidemiologically and physiologically, contributing to high mortality and poor growth and development of children in sub-Saharan Africa. This thesis aims to explore the impact of HIV on the treatment and care of children with severe acute malnutrition in Malawi. The thesis will investigate mortality and nutritional recovery in HIV-infected and uninfected children with SAM; HIV infection and n
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2

Kellerhals, Sarah. "Understanding Severe Acute Malnutrition in Children Globally: A Systematic Review." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/624202.

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A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.<br>Severe acute malnutrition (SAM) affects 13 million children under the age of 5 worldwide, and contributes to 1‐2 million preventable deaths each year. Malnutrition is a significant factor in approximately one third of the nearly 8 million deaths in children who are under 5 years of age worldwide. There have been many revolutions in treatment of SAM over time; however, the exact etiology of this preventable condition is not well unders
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3

Piniel, Abigail. "Factors contributing to severe acute malnutrition among the under five children in Francistown-Botswana." Thesis, University of the Western Cape, 2016. http://hdl.handle.net/11394/5253.

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Magister Artium (Child and Family Studies) - MA(CFS)<br>Introduction: Malnutrition is the immediate result of inadequate dietary intake, the presence of disease or the interaction between these two factors. It is a complicated problem, an outcome of several etiologies. SAM is one of the leading causes of morbidity and mortality among children under the age of five in developing countries. Although studies in Botswana show some improvement in child malnutrition since the 1980s, severe acute malnutrition still remains a cause for concern in many parts of the country. There is little information
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4

Sadler, K. "Community-based therapeutic care : treating severe acute malnutrition in sub-Saharan Africa." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/16480/.

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Severe acute malnutrition (SAM) affects approximately 13 million children under-five and is associated with over 1.5 million preventable child deaths each year. Case fatality rates in hospitals treating SAM remain at 20-30%, and coverage of those affected remains low. Training and support to improve centre-based management can reduce case fatality rates. However, an exclusive inpatient approach does not consider the many barriers to accessing treatment that exist for poor people in the developing world. Community-based therapeutic care (CTC) is a new approach for the management of SAM that use
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5

Tadesse, Elazar. "Integrated community-based management of severe acute child malnutrition : Studies from rural Southern Ethiopia." Doctoral thesis, Uppsala universitet, Internationell mödra- och barnhälsovård (IMCH), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-292781.

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Background: The World Health Organization (WHO) recommends the community-based Outpatient Therapeutic Program (OTP) as a standard treatment protocol for the management of uncomplicated Severe Acute Malnutrition (SAM) at the community level. OTP has been scaled up and integrated into the existing grassroots level government health systems in several developing countries. The aim of this thesis was to assess the implementation and outcome of a scaled-up and integrated OTP service provided at community level. Methods: One qualitative study and three quantitative studies were conducted in southern
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6

Dailey-Chwalibóg, Trenton. "Biomedical Investigations for the Optimized Diagnosis and Monitoring of Severe Acute Malnutrition : The OptiDiag Study." Thesis, Paris, Institut agronomique, vétérinaire et forestier de France, 2020. http://www.theses.fr/2020IAVF0005.

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Les recommandations actuelles de l’OMS séparent les enfants atteints de malnutrition aiguë sévère (MAS) non-œdémateux en trois phénotypes anthropométriques : faible périmètre brachiale (PB) seul ; faible indice poids-taille (IPT) seul ; ou faible PB et ITP. Tous sont éligibles à une réhabilitation nutritionnelle selon les lignes directrices de l’OMS.Cependant, pour des raisons de facilité d’utilisation, et sur la base de données suggérant une surmortalité chez les enfants atteints de MAS diagnostiquée par le seul PB, plusieurs agences et gouvernements considèrent ce dernier critère comme néces
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7

Boltena, Sisay Sinamo. "Factors affecting the rehabilitation outcome (of outpatient therapeutic program) of children with severe acute malnutrition in Durame, Southern Ethiopia." Thesis, UWC, 2008. http://hdl.handle.net/11394/2868.

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Magister Public Health - MPH<br>Background: Malnutrition accounted high level of childhood morbidity and mortality in Ethiopia including Durame area. Durame area is one of the food insecure districts in Southern region. As a result of high prevlanece of acute malnutrtion, which is 8.3%, Ministry of Health partnering with World Vision Ethiopia started outpatient therapeutic program (OTP) in seven OTP sites to rehablitate severely malnourished children. Reports indicate that number of factors affect the rehabilitation outcome of children with severe acute malnutrtion in OTP programs. However, th
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8

Mwanza, Mike. "Evaluation of the outpatient therapeutic programme for management of severe acute malnutrition in three districts of eastern province , Zambia." University of Western Cape, 2013. http://hdl.handle.net/11394/3919.

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Magister Public Health - MPH<br>The Outpatient Therapeutic Programme (OTP) is an integrated public health innovation for treating severe acute malnutrition without medical complications in children 6 to 59 months of age as outpatients within their communities using Ready to Use Therapeutic Food with the aim of reducing case fatality rates. The OTP approach is implemented in the three districts in Eastern Province of Zambia namely; Chipata, Katete and Petauke. Since inception of the OTP in the province, an evaluation of the OTP has not been conducted. The study is aimed at assessing the effect
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9

Akparibo, Robert. "A realist evaluation of community-based model used to treat children suffering from severe-acute malnutrition in non-emergency context in Ghana." Thesis, University of Sheffield, 2014. http://etheses.whiterose.ac.uk/6671/.

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Background: The effectiveness of community-based programmes to treat children suffering from Severe-Acute Malnutrition (SAM) is well documented following their implementation in emergency situations. However, little evidence exists to understand whether these programmes when implemented in non-emergency situation can also achieve successful outcomes. It is only recently (2007) that the community-based approach was approved by the WHO, and adopted by governments of developing countries to be implemented as part of routine health care services. Since then little or no organised research has expl
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10

Tidjani, Alou Maryam. "Etude du microbiote digestif des enfants atteints de malnutrition sévère aiguë." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5036/document.

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Depuis plusieurs années, il s’avère de plus en plus clair que le microbiote digestif a un impact remarquable sur la santé humaine. Il est affecté par de nombreux facteurs dont l’alimentation. En effet, en fonction du macronutriment majoritaire d’un régime alimentaire, certaines populations et fonctions bactériennes sont stimulées ou inhibées. Plusieurs pathologies de l’intestin ou liées à des troubles nutritionnels ou métaboliques ont un lien causal avec une altération du microbiote digestif parmi lesquelles la malnutrition sévère aigue. En effet, il a été récemment montré que le microbiote di
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11

Palmer, R. A. C. "Emotional stimulation as an addition to therapeutic food intervention for treatment of young children with severe acute malnutrition in a low-income country." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1532876/.

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This thesis presents the results of a series of studies evaluating the potential of a short, low-cost intervention aiming to enhance the sensitivity of mothers of severely malnourished children in Ethiopia. The emotional stimulation (ES) intervention was integrated with the existing nutrition programme and delivered by local health workers and lay workers. There are five empirical chapters. 1) A pilot trial of the ES intervention, which demonstrated that it was feasible to implement the intervention in Ethiopia and provided preliminary evidence of the intervention’s potential. 2) A cluster ran
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12

van, Aswegen Tanya. "Factors associated with morbidity and mortality in children under-five years admitted with severe acute malnutrition to a regional paediatric hospital in Kwazulu-Natal." University of the Western Cape, 2018. http://hdl.handle.net/11394/6741.

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Magister Public Health - MPH<br>Background: Malnutrition is a complex condition profoundly impacting child mortality and morbidity, especially in sub-Saharan Africa. Severe acute malnutrition is of growing concern locally where unacceptable mortality rates persist, despite reasonable standards of clinical care. Aim: To determine factors associated with morbidity and mortality in children under-five years admitted with severe acute malnutrition to a regional paediatric hospital in KwaZulu-Natal. Methodology: This was a quantitative study. A retrospective observational study design was used
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13

Pham, Thi Phuong Thao. "Caractérisation du microbiote intestinal des enfants atteints de la malnutrition aigüe sévère." Thesis, Aix-Marseille, 2019. http://www.theses.fr/2019AIXM0583.

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La distinction entre kwashiorkor et marasme a été remise en question depuis longtemps. Comprendre les mécanismes pathophysiologiques distincts de la malnutrition sévère ouvrira les portes de nouvelles options thérapeutiques. Dans cette thèse, des échantillons fécaux prélevés chez 17 enfants atteints de malnutrition aigüe sévère ont été testées par culturomics et séquençage métagénomique 16S pour examiner les différences du microbiote intestinal. Les méta-analyses sont effectués pour fournir des caractéristiques cohérentes et reproductibles qui différencient kwashiorkor et marasme. Il existe un
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14

Grellety, Bosviel Emmanuel. "Analysis of variation of mid-upper arm circumference and weight-for-height in children for the assessment of malnutrition in populations and individuals." Doctoral thesis, Universite Libre de Bruxelles, 2019. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/283364.

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Death from hunger and starvation can be avoided with appropriate diagnosis and treatment if the necessary knowledge and resources are available. The current definitions of acute malnutrition are based either upon a weight-for-height Z-score (WHZ) below -2 standard deviations of the international reference population (World Health Organization 2006 Growth Standards) or a mid-upper arm circumference (MUAC) lower than 125 mm. These indicators are used independently to define the sum of moderate and severe acute malnutrition, commonly referred to as global acute malnutrition (GAM). Severe acute ma
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15

Salameh, Emmeline. "Développement d'un modèle murin de dénutrition avec entéropathie et évaluation de molécules d'intérêt permettant de contribuer au rétablissement de la fonction de barrière intestinale." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMR064.

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Contexte : La malnutrition aiguë sévère (MAS) est un problème majeur de santé publique dans lemonde et affecte 17 millions d’enfants âgés de moins de 5 ans. La MAS induit une perte de poidsrapide, souvent associée à une dysfonction entérique environnementale (DEE). La DEE se caractérisepar une augmentation de l’inflammation, de la perméabilité intestinale, une diminution de la taille des villosités et de l’absorption des nutriments. La DEE peut ainsi limiter l’efficacité des protocolesde stabilisation et de re-nutrition chez l’enfant dénutri.L’objectif de cette thèse a été de développer un mod
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16

Kerac, M. "Improving the treatment of severe acute malnutrition in childhood : a randomized controlled trial of synbiotic-enhanced therapeutic food with long term follow-up of post-treatment mortality and morbidity." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1306755/.

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BACKGROUND: Tackling severe acute malnutrition (SAM) is a global public health priority. This thesis explores two major influences on treatment outcomes: -Treatment efficacy -Patient-related risk factors OBJECTIVES: 1. To explore whether a pre/probiotic mixture (Synbiotic2000 Forte™) improves treatment outcomes (nutritional and clinical) in children affected by SAM. 2. To describe long term outcomes from SAM and identify key mortality risk factors. METHODS: All 1024 malnourished children admitted to a therapeutic feeding centre in Malawi from July 2006 to March 2007 were eligible for: The PRON
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17

Mclaren, Britta Jane. "Lactose malabsortion and diarrhoea in children with severe acute malnutrition." Thesis, 2015. http://hdl.handle.net/10539/19956.

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A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, in partial fulfilment of the requirements for the degree of Master or Medicine in the branch of Paediatrics Johannesburg, 2015<br>Malnutrition and diarrhoea are major causes of childhood morbidity and mortality in the developing world. Lactose malabsorption has been associated with diarrhoea in malnourished children, but they are often managed with lactose containing feeds. This study quantified the prevalence of lactose malabsorption in children with severe acute malnutrition (SAM) and diar
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18

Demisse, Bekele Negussie. "Performance of community-based management of children with severe acute malnutrition in a pastoral area of Ethiopia." Diss., 2013. http://hdl.handle.net/10500/13393.

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The purpose of the study was to assess the coverage and effectiveness of the management of severe acute malnutrition project implemented in Dhas district of Borena zone, Ethiopia, from July 2010 to December 2010. Quantitative, descriptive study was conducted to assess the comparability of the outcome of community-based management of acute malnutrition in a pastoralist area to International Sphere standards using performance indicators. Data collection was done using data capturing sheet. Outpatient therapeutic programme (OPT) registers in all health facilities were the sources of data. Clinic
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19

Anthony, A. C. "Assessment of clinical practices in children admitted with severe acute malnutrition in three district hospitals, in the Western Cape, South Africa." 2013. http://hdl.handle.net/11394/3208.

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Master of Public Health - MPH<br>Background: Severe acute malnutrition contributes disproportionately to child mortality rates despite availability of the WHO protocol, “Ten Steps”, to guide hospital management. Auditing morbidity and mortality rates of malnourished children at hospitals is useful to measure the effectiveness of hospital-based management compared to standards advocated by the WHO protocol. The study aimed to assess the adequacy of clinical management practices for severely malnourished children admitted to three district hospitals in the Western Cape as compared to the WHO gui
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20

Armini, Vincenzo. "Development of a Local and Alternative Ready-to-Use Therapeutic Food (RUTF) suitable for Community-based Management of Severe Acute Malnutrition." Tesi di dottorato, 2018. http://www.fedoa.unina.it/12603/1/armini_vincenzo_30.pdf.

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In order to produce a local Ready-to-Use Therapeutic Food (RUTF) alternative to Plumpy 'Nut ® commercial, based on dehusked, roasted and pulverized soy and sorghum ingredients, Arthrospira maxima (Spirulina) dried and pulverized, sunflower oil and powdered sugar, based on nutritional specifications suggested by the Food and Agriculture Organization of the United Nations (FAO) and the United Nations International Children's Fund (UNICEF) for the RUTF for the treatment of Acute Severe Malnutrition (MAS), a experimental design D-Optimal Design with three variables (sorghum and soy flours, sugar,
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