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Dissertations / Theses on the topic 'Severity of liver damage'

Author: Grafiati

Published: 28 September 2024

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1

Habib, Shahid, Khalid Khan, Chiu-Hsieh Hsu, Edward Meister, Abbas Rana, and Thomas Boyer. "Differential Simultaneous Liver and Kidney Transplant Benefit Based on Severity of Liver Damage at the Time of Transplantation." ELMER PRESS INC, 2017. http://hdl.handle.net/10150/625529.

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Background: We evaluated the concept of whether liver failure patients with a superimposed kidney injury receiving a simultaneous liver and kidney transplant (SLKT) have similar outcomes compared to patients with liver failure without a kidney injury receiving a liver transplantation (LT) alone. Methods: Using data from the United Network of Organ Sharing (UNOS) database, patients were divided into five groups based on pre-transplant model for end-stage liver disease (MELD) scores and categorized as not having (serum creatinine (sCr) <= 1.5 mg/dL) or having (sCr > 1.5 mg/dL) renal dysfunction.

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2

Zambon, Azevedo Vittoria. "Mise au point d’un nouvel outil diagnostique de l’obésité sarcopénique : relations avec la dysfonction du tissu adipeux, l’insulinorésistance et la sévérité de l’atteinte hépatique." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS170.pdf.

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L'obésité sarcopénique (OS) est une condition caractérisée par la coexistence de l'obésité et de la sarcopénie, c'est-à-dire une réduction de la masse et de la fonction musculaires. Diagnostiquer l'OS est très complexe en raison de l'absence de critères diagnostiques universellement acceptés, ce qui entraîne des diagnostics imprécis et une estimation hautement variable de sa prévalence. Face à ces limitations, l'objectif de cette thèse était de développer un outil de diagnostic empirique pour l'OS aidé d'intelligence artificielle, basé sur l'analyse de la composition corporelle. Nous avons éla

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3

Fisher, D. R. "Studies on residual damage in irradiated liver." Thesis, University of Manchester, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355903.

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4

Nowak, Urszula. "Rheumatoid factor production in response to liver damage." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84065.

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Many liver diseases such as Alcoholic Liver Disease and Hepatitis C are associated with the production of autoantibodies. One of these autoantibodies is Rheumatoid Factor (RF), which binds to IgG and can aid in host defense. Since little is known about the role of RF in liver disease, we characterized the production of this autoantibody in three murine models of liver damage using alcohol, anti-Fas antibodies and carbon tetrachloride. RF was induced in response to chronic alcohol consumption as well as intraperitoneal injection of anti-Fas antibodies. RF was not produced in response to

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5

Miyachi, Yosuke. "Causes of liver steatosis influence the severity of ischemia reperfusion injury and survival after liver transplantation in rats." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263516.

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6

Müller, Hans Christian. "Alternative strategies to reduce liver abscess incidence and severity in feedlot cattle." Thesis, Kansas State University, 2017. http://hdl.handle.net/2097/38157.

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Master of Science<br>Department of Animal Sciences and Industry<br>James S. Drouillard<br>Since the 1960’s liver abscess incidence and severity have been identified as a problem associated with feeding high concentrate finishing rations to feedlot cattle. Liver abscesses lead to decreased feedlot performance and decreased carcass value. Tylosin phosphate is a macrolide antibiotic commonly used by feedlots throughout the United States and has been shown to successfully control liver abscesses. In 2013, the FDA issued Guidance for Industry #213, which encourages reduced usage of medically import

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7

Haydon, Geoffrey H. "The severity and activity of liver disease in chronic hepatitis C infection." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/28213.

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The aims were twofold. Firstly, to assess the clinical significance of staging investigations; in particular the significance of molecular virological investigations in terms of disease diagnosis and prognosis. The role of non-invasive investigations in staging the disease process was also considered. Secondly, the impact of chronic hepatitis C infection was assessed in two populations; patients diagnosed as having hepatocellular carcinoma and those immunocompromised chronic HIV infection. In the Scottish population studied, both serum and intrahepatic virus levels were not determined by host

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8

Kistler, Kristin David. "Nonalcoholic fatty liver disease quality of life, exercise intensity and histological severity /." Diss., [La Jolla] : [San Diego] : University of California, San Diego ; San Diego State University, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p3359523.

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Thesis (Ph. D.)--University of California, San Diego and San Diego State University, 2009.<br>Title from first page of PDF file (viewed July 21, 2009). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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9

Висоцький, Ігор Юрійович, Игорь Юрьевич Высоцкий, Ihor Yuriiovych Vysotskyi, et al. "Chronopharmacological peculiaries of antioxidants action in toxic liver damage." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41261.

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10

Holland, Michael J. "Measuring Disease Damage and its Severity in Childhood-Onset Systemic Lupus Erythematosus." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1527606864223975.

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11

Nalapareddy, Padmavathi Devi [Verfasser]. "Role of bid in liver injury following BDL and CCl4-induced liver damage / Padmavathi Devi Nalapareddy." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover, 2010. http://d-nb.info/1004974523/34.

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12

Soare, Catalina P. "Characterization of Liver Damage Mechanisms Induced by Hepatitis C Virus." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20343.

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Hepatitis C Virus (HCV) is one of the most important causes of chronic liver disease, affecting more than 170 million people worldwide. The mechanisms of hepatitis C pathogenesis are unknown. Viral cytotoxicity and immune mediated mechanisms might play an important role in its pathogenesis. HCV infection and alcohol abuse frequently coexist and together lead to more rapid progression of liver disease, increasing the incidence and prevalence of cirrhosis and hepatocellular carcinoma. The cytopathic effect of HCV proteins, especially the core, E1 and E2 structural proteins, which induce liver st

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13

Pereira, Pedro Miguel Miranda Sousa Gonçalves. "Severity and extent of tissue damage in human and experimental temporal lobe epilepsy." Doctoral thesis, Instituto de Ciências Biomédicas Abel Salazar, 2007. http://hdl.handle.net/10216/7259.

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14

Pereira, Pedro Miguel Miranda Sousa Gonçalves. "Severity and extent of tissue damage in human and experimental temporal lobe epilepsy." Tese, Instituto de Ciências Biomédicas Abel Salazar, 2007. http://hdl.handle.net/10216/7259.

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15

Knight, Trudy Lynn. "The molecular basis of halothane-induced hepatotoxicity." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321782.

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16

Pesce, Paola. "Non Alcoholic Fatty Liver Disease: non invasive markers of severity and new experimental treatments." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3422225.

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Non Alcoholic Fatty Liver Disease (NAFLD) is a worldwide increasing disease but still many questions about its evolution, the need of a screening and the availability of effective specific treatments are open. Aims of this PhD project were: 1) the evaluation of NAFLD natural history in a subgroup of NAFLD affected diabetic patients enrolled during the daily clinical activity of a splenohepatology ecoDoppler laboratory in order to identify, if present, predictive factors of “evolutive NAFLD”; 2) the experimental evaluation, in High Fat Diet (HFD) fed rats, of the potential therapeutic effect

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17

Marker, Alison Jean. "Mechanisms of regulation of liver metabolism and growth." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287759.

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18

Upadhyaya, Sneha. "Development of an Improved and Internally-Consistent Framework for Evaluating Liquefaction Damage Potential." Diss., Virginia Tech, 2019. http://hdl.handle.net/10919/95941.

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Soil liquefaction continues to be one of the leading causes of ground failure during earthquakes, resulting in significant damage to infrastructure around the world. The study presented herein aims to develop improved methodologies for predicting liquefaction triggering and the consequent damage potential such that the impacts of liquefaction on natural and built environment can be minimized. Towards this end, several research tasks are undertaken, with the primary focus being the development of a framework that consistently and sufficiently accounts for the mechanics of liquefaction triggerin

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19

Anwar, Khurshid. "Role of apoptosis (programmed cell death) in acute liver failure." Thesis, University of Surrey, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370058.

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20

Kulachek, Y. V., F. G. Kulachek, and V. T. Kulachek. "Estimation of severity of the early period of traumatic disease in victims with liver injury." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/16910.

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21

Yasmin, Mahmuda. "Molecular biology of fulminant hepatitis B viruses." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360121.

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22

Ramirez, Javier. "Identification of sites of ethanol-derived protein adducts involved in liver damage." Tallahassee, Fla. : Florida State University, 2010. http://purl.fcla.edu/fsu/lib/digcoll/undergraduate/honors-theses/2181934.

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Thesis (Honors paper)--Florida State University, 2010.<br>Advisor: Dr. Mark Kearley, Florida State University, College of Arts and Sciences, Dept. of Chemistry and Biochemistry. Includes bibliographical references.

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23

Cass, Stacie Ann. "The effects of sexual harassment severity and organizational policy and response on juror damage awards." FIU Digital Commons, 2002. http://digitalcommons.fiu.edu/etd/2068.

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Community members who reported for jury duty (N = 123) read a brief summary of a sexual harassment trial, in which harassment severity and the organization's sexual harassment policy were manipulated. Jurors were more likely to agree that they should compensate the plaintiff for her pain and suffering, the organization should be punished, and the plaintiff had suffered when they read the more severe harassment scenario. When the organization had and enforced an effective sexual harassment policy, jurors believed that the plaintiff had suffered little and the organization should not be punished

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24

Ghallab, Ahmed [Verfasser]. "Spatial-temporal modelling of liver damage as well as regeneration and its influence on metabolic liver function / Ahmed Mohammed Ghallab." Gießen : Universitätsbibliothek, 2013. http://nbn-resolving.de/urn:nbn:de:hebis:26-opus-98761.

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25

Ghallab, Ahmed Mohammed [Verfasser]. "Spatial-temporal modelling of liver damage as well as regeneration and its influence on metabolic liver function / Ahmed Mohammed Ghallab." Gießen : Universitätsbibliothek, 2013. http://d-nb.info/1065320353/34.

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26

Gewiese, Jessica [Verfasser]. "Role of IL-6 Transsignaling in acute CCl4-induced liver damage / Jessica Gewiese." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/1019982640/34.

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27

Yang, Sitian, and 楊斯恬. "Novel role of drug-induced non homologous end joining factor 1 in the chemoresistance of hepatocellular carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2015. http://hdl.handle.net/10722/209505.

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28

Suh, Jihee. "Evaluation of Association of MicroRNA-122 with Histological Severity of Recurrent HCV Infection in Liver Transplant Recipients." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1890.

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Hepatitis C virus recurrence (which is defined by detection of HCV RNA in serum) in post-transplanted liver is universal but the progression of infection remains unpredictable, varying from case to case. It has been estimated that 75%-80% of the HCV recurrence patients will suffer chronic hepatitis C infection and up to a third of them will progress into the development of fibrosis and cirrhosis within 5 years post-transplantation. Therefore, finding ways to predict early on the progression of fibrosis can contribute to better prognoses. Recent literatures have mentioned that the hepatitis C v

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29

Sparks, Jessica L. "Biomechanics of blunt liver injury relating internal pressure to injury severity and developing a constitutive model of stress-strain behavior /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1185909955.

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30

Buitrago, Molina Laura Elisa [Verfasser]. "mTOR inhibition impairs proliferation of hepatocytes with DNA damage during chronic liver injury thereby delaying liver tumor development / Laura Elisa Buitrago Molina." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover, 2010. http://d-nb.info/1009414127/34.

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31

Arp, Melanie K. "The frequency and severity of problem behaviors among individuals with autism, traumatic brain injury, and mental retardation from the Utah DSPD dataset /." Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1050.pdf.

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32

Cowan, Matthew Lawson. "The application of proteomics to the discovery of biomarkers of diseases severity and prognosis in chronic liver disease." Thesis, St George's, University of London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568724.

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Chronic liver disease (CLD) is a major and growing healthcare burden but is asymptomatic until liver fibrosis is advanced. Antiviral therapy can cure 50% with chronic hepatitis C virus (HCV) infection. Accurate staging of fibrosis requires invasive liver biopsy; predicting response to antivirals prior to the start of treatment is not possible. Clinical details, serum, plasma and liver tissue for 443 subjects with CLD were collected in a purpose-built database. Patients undergoing staging liver biopsy or HCV antiviral therapy were recruited prospectively; HCV patients with gold standard liver b

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33

Кононенко, Микола Григорович, Николай Григорьевич Кононенко, Mykola Hryhorovych Kononenko та І. М. Лукавенко. "Пошкодження печінки". Thesis, Видавництво СумДУ, 2004. http://essuir.sumdu.edu.ua/handle/123456789/9454.

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34

Кононенко, Микола Григорович, Николай Григорьевич Кононенко, Mykola Hryhorovych Kononenko, Андрій Олександрович Бойчунь та Andrii Oleksandrovych Boichun. "Актуальні питання артеріального гемостазу при пошкодженні печінки". Thesis, Видавництво СумДУ, 2009. http://essuir.sumdu.edu.ua/handle/123456789/6696.

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35

Лішневська, Анастасія Геннадіївна, Анастасия Геннадьевна Лишневская, and Anastasiia Hennadiivna Lishnevska. "Degree of severity of laboratory syndromes in patients whith chronic viral hepatitis C." Thesis, Sumy State University, 2018. http://essuir.sumdu.edu.ua/handle/123456789/70787.

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У світі існує близько 71 мільйона людей, які страждають на ВГС. Приблизно половина смертельних випадків зумовлена цирозом печінки та печінковою клітинною карциномою.<br>В мире около 71 миллиона человек имеют инфекцию ВГС. Примерно половина смертельных случаев вызвана циррозом и гепатоцеллюлярной карциномой.<br>In the world there areabout 71 million people who have an HCV infection. Approximately half of the fatal cases are cused by cirrhosis and hepatocellular carcinoma.

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36

Lee, Matthew L., and Jonathan M. Peterson. "CTRP3 Protects Liver Cells From Alcohol-Induced Damage, But Not Through Enhanced Akt Signaling Type." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/70.

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Alcoholic fatty liver disease (AFLD) is a significant public health concern. Excessive alcohol (ethanol) consumption causes liver cell damage and death, which results in eventual failure of the liver and death. AFLD is the number one cause of liver-related mortality in the United States. Our lab works with the novel protein C1q TNF Related Protein 3 (CTRP3), which inhibits non-alcoholic fatty liver disease, however the effects on AFLD are unknown. Therefore, the purpose of this experiment is to determine if CTRP3 prevents ethanol-induced liver cell death. The H4IIE rat hepatoma cell line was c

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37

Smart, Kevin Arthur. "The mechanism by which hyperammonaemia may cause hepatic encephalopathy." Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267312.

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38

Vilfranc, Chrystelle L. "Elucidating the Role of BRUCE in Chronic Liver Disease Pathogenesis." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1617107353008576.

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39

Finnberg, Niklas. "The attenuation of the P53 response to DNA damage in rodent liver preneoplastic enzyme-altered foci /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-462-3.

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40

Ye, Xingshen. "Studies on effects of coptis extract and berberine against carbon tetrachloride-induced liver damage in rats." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38718832.

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41

Ghafoory, Shahrouz [Verfasser], and Stefan [Akademischer Betreuer] Wölfl. "Gene expression recovery during an acute toxic damage in the liver / Shahrouz Ghafoory ; Betreuer: Stefan Wölfl." Heidelberg : Universitätsbibliothek Heidelberg, 2015. http://d-nb.info/118039688X/34.

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42

Ye, Xingshen, and 叶星沈. "Studies on effects of coptis extract and berberine against carbon tetrachloride-induced liver damage in rats." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38755208.

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43

Gibhard, Liezl. "Ozone autohaemotherapy protects against Ketamine hydrochloride® induced liver and muscle damage in baboons / L. Gibhard." Thesis, North-West University, 2007. http://hdl.handle.net/10394/759.

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Ozone therapy has been used as a form of alternative medicine but has encountered scepticism by orthodox medicine concerning its effectiveness and toxicity. We assessed the acute and chronic effect of O3 autohaemotherapy (AHT) on liver and muscle damage in baboons. During the acute effect three groups of baboons were used. The first group (n=11) were treated with an O2/O3 gas mixture containing different ozone concentrations i.e. 20, 40 and 80 μg/ml O3 . The second group (n=5) were treated with pure O2 and the third group (n=3) received no treatment and were used to assess the effect of ketami

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44

Kamimura, Ryo. "Comparative study of transplantation of hepatocytes at various differentiation stages into mice with lethal liver damage." Kyoto University, 2012. http://hdl.handle.net/2433/157436.

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45

Gao, Yong. "Noninvasive monitoringn of CCl4 induced acute and chronic liver damage in rat by single quantum and triple quantum filtered 23Na magnetic resonance imaging." Connect to resource online, 2008. http://hdl.handle.net/1805/2045.

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Thesis (M.S.)--Indiana University, 2008.<br>Title from screen (viewed on January 26, 2010). Department of Cellular & Integrative Physiology, Indiana University-Purdue University Indianapolis (IUPUI). Advisor(s): Navin Bansal, Andriy M. Babsky, Stephen A. Kempson, David P. Basile. Includes vitae. Includes bibliographical references (leaves 33-36).

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46

Wali, Mohamed Hatem Fathi El-Saied. "Natural history, factors affecting severity and progression rate of hepatitis C virus (HCV) infection in liver transplanted and non-transplanted patients." Thesis, University of Birmingham, 2002. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269215.

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47

Zohora, Fatematuz. "Evaluation of material crack using acoustic emission technique." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/94663/1/Fatematuz_Zohora_Thesis.pdf.

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Cracks in civil structures can result in premature failure due to material degradation and can result in both financial loss and environmental consequences. This thesis reports an effective technique using Acoustic Emission (AE) technique to assess the severity of the crack propagation in steel structures. The outcome of this work confirms that combination of AE parametric analysis and signal processing techniques can be used to evaluate crack propagation under different loading configurations. The technique has potential application to assess and monitor the condition of civil structures.

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48

Billing, S. E. "An evaluation of different methods of measuring lipid peroxidation and their application to the assessment of liver cell damage induced by certain hepatoxic agents." Thesis, Brunel University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383745.

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49

Rose, David Harry. "A Cumulative Damage Approach to Modeling Atmospheric Corrosion of Steel." University of Dayton / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1417085212.

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50

Amin, Alla Mohammed Hussain. "Cold ischaemia and reperfusion injury in liver : the potential for damage to cellular DNA in the rat model." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248455.

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