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Journal articles on the topic 'Seymour family'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Vikhrova, K. A. "“Personal drama defined by history”: Philip Roth’s artistic method in “American pastoral”." Practices & Interpretations: A Journal of Philology, Teaching and Cultural Studies 8, no. 2 (2023): 95–107. http://dx.doi.org/10.18522/2415-8852-2023-2-95-107.

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The article analyzes the implementation of Philip Roth’s (1933–2018) artistic method in the novel “American Pastoral”, which connects the historical events with a personal family drama and problematizes the Jewish identity in diaspora. The analysis shows that several key events from the history of the United States (the second half of the 20th century) were used as a conceptual basis for narrative structure and for the set of characters. World War II, the Vietnam War, which Roth had not previously discussed in a comprehensive manner, the 1967 Newark riots, and the Watergate scandal turn out to

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Harasewych, M. G., Anton Oleinik, and William Zinsmeister. "The Cretaceous and Paleocene pleurotomariid (Gastropoda: Vetigastropoda) fauna of Seymour Island, Antarctica." Journal of Paleontology 83, no. 5 (2009): 750–66. http://dx.doi.org/10.1666/09-004.1.

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Leptomaria antipodensis and Leptomaria hickmanae are described from the Upper Cretaceous [Maastrichtian] Lopez de Bertodano Formation, Seymour Island, and represent the first Mesozoic records of the family Pleurotomariidae from Antarctica. Leptomaria stillwelli, L. seymourensis, Conotomaria sobralensis and C. bayeri, from the Paleocene [Danian], Sobral Formation, Seymour Island, are described as new. Leptomaria larseniana (Wilckens, 1911) new combination, also from the Sobral Formation, is redescribed based on better-preserved material. The limited diversity of the pleurotomariid fauna of Seym

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Shinde*, Vaishali, and A. B. Pawar. "Some new records of lower aquatic fungi from western Maharashtra, Maharashtra State, India." International Journal of Bioassays 5, no. 02 (2016): 4846. http://dx.doi.org/10.21746/ijbio.2016.02.0013.

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Present study deals with the study of some lower aquatic fungi different regions of Maharashtra viz., Acaulopage dichotoma Drechsler belong to family Zoophagacea (Class- Zygomycetes) while Achlya oblongata de Bary, Brevilegnia megasperma Harvey, Saprolegnia ferax (Gruith) Thuret and Saprolegnia subterranae (Dissman) Seymour belongs to family Saprolegniaceae (Class - Oomycetes). All these are new records of aquatic fungi from the Maharashtra state.

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Long, Douglas J. "An Eocene wrasse (Perciformes; Labridae) from Seymour Island." Antarctic Science 4, no. 2 (1992): 235–37. http://dx.doi.org/10.1017/s095410209200035x.

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A nearly complete lower pharyngeal tooth-plate from a large (over 60 cm long) fossil wrasse (Perciformes: Labridae) was recently recovered from the middle to late Eocene La Meseta Formation on Seymour Island, Antarctic Peninsula. This find increases the number of teleosts from the Eocene of Antarctica to five taxa, and further illustrates the diversity of the ichthyofauna in the Eocene Weddellian Sea prior to wide-scale climatic change in the Southern Ocean. The fossil wrasse represents the first occurrence of this family in Antarctica, and is one of the oldest fossils of this family from the

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5

Di Bona, Joseph. "Women, Education, and Family Structure in India. Carol Chapnick Mukhopadhyay , Susan Seymour." Comparative Education Review 39, no. 1 (1995): 161–63. http://dx.doi.org/10.1086/447302.

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6

Macellari, Carlos E. "Late Campanian–Maastrichtian Ammonite Fauna from Seymour Island (Antarctic Peninsula)." Journal of Paleontology 60, S18 (1986): 1–55. http://dx.doi.org/10.1017/s0022336000060765.

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One of the richest and best preserved late Campanian-Maastrichtian ammonite faunas of the world occurs within the Lopez de Bertodano Formation on Seymour Island. The excellent exposure of this sequence has offered an opportunity for detailed stratigraphic study of the fauna, providing a stratigraphic control unavailable for most other Southern Hemisphere strata of similar age.Ammonites are restricted to the Cretaceous portion of the Lopez de Bertodano Formation, becoming more abundant and increasing in diversity within a 600-m interval below the Cretaceous-Tertiary boundary. The ammonite-rich

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Kopczyński, Tomasz. "Computational thinking in the context of self-developmentand the family." Family Upbringing 27, no. 2 (2022): 167–82. http://dx.doi.org/10.61905/wwr/170345.

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<b>Cel.</b> Celem artykułu jest przedstawienie zagadnienia myślenia komputacyjnego w szerszym kontekście czasopiśmiennictwa anglojęzycznego w obszarach działań samorozwojowychz uwzględnieniem pojęcia oddziaływania środowiska rodziny. Termin <i>myślenie komputacyjne</i> już na dobre występuje w różnego opracowaniach edukacyjnych, jednak rzadko jest rozpatrywany w szerszym kontekście edukacyjnym takim jak rodzina czy samodoskonalenie. Artykuł sygnalizuje problemy, które były już wcześniej wskazywane przez znawców tematu, a jedynie nasiliły się w wyniku edukacji postpandem

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8

Leonard, Karen. "Women, Education, and Family Structure in India.Carol Chapnick Mukhopadhyay and Susan Seymour, eds." American Anthropologist 97, no. 2 (1995): 385–86. http://dx.doi.org/10.1525/aa.1995.97.2.02a00400.

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9

Amoorthy, R. Soory. "SEYMOUR, Susan C., WOMEN, FAMILY AND CHILD CARE IN INDIA: A World in Transition." Journal of Comparative Family Studies 31, no. 1 (2000): 134–35. http://dx.doi.org/10.3138/jcfs.31.1.134.

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10

Vizcaíano, Sergio F., and Gustavo J. Scillato-Yané. "An Eocene tardigrade (Mammalia, Xenarthra) from Seymour Island, West Antarctica." Antarctic Science 7, no. 4 (1995): 407–8. http://dx.doi.org/10.1017/s0954102095000563.

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Carlini et al. (1990) reported the presence of Xenarthra (Mammalia) from the Eocene deposits of Seymour Island, Antarctic Peninsula, based on an ungual phalanx from locality RV 8200. The locality, referred to informally as “mammal site” by Woodburne & Zinsmeister (1984), is located at 64°14′21″S, 56°39′44″W at an elevation of 45 m in the middle levels of the shallow marine La Meseta Formation (TELM 5 of Saddler 1988). Carlini et al. (1990) initially identified the phalanx as a megatherioid sloth (Order Tardigrada). Marenssi et al. (1994) revised its identification to ?Tardigrada or ?Vermil

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11

Cione, Alberto L., and M. A. Reguero. "A middle Eocene basking shark (Lamniformes, Cetorhinidae) from Antarctica." Antarctic Science 10, no. 1 (1998): 83–88. http://dx.doi.org/10.1017/s095410209800011x.

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A proximal fragment of a gill raker identified as belonging to a shark of the genus Cetorhinus was collected from middle Eocene deposits of the La Meseta Formation in the northern part of Seymour Island, Antarctica. This is the first record of a fossil basking shark from Antarctica and one of the earliest records of the genus. The minimum age of Cetorhinidae is middle Eocene. The only living species of the family Cetorhinidae is a very large plankton feeder, Cetorhinus maximus. Basking sharks are unknown in subantarctic or Antarctic waters but occur on both South American coasts today. The evo

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Mitchell, Edward D. "A New Cetacean from the Late Eocene La Meseta Formation Seymour Island, Antarctic Peninsula." Canadian Journal of Fisheries and Aquatic Sciences 46, no. 12 (1989): 2219–35. http://dx.doi.org/10.1139/f89-273.

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The new genus and species Llanocetus denticrenatus is described based on a cranial endocast and portion of a dentary fragment bearing two teeth from the Eocene La Meseta Formation, Seymour Island, Antarctic Penninsula. Llanocetus new genus is designated the type genus for the new family Llanocetidae. The Llanocetidae is placed within the new infraorder Crenaticeti, co-ordinate with the new Mysticete infraorder Chaeomysticeti. Llanocetus denticrenatus new species shows relationship with both Archaeoceti and Mysticeti. Revision of archaeocete and mysticete classification includes proposal of the

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Hara, Urszula. "Bryozoan internal moulds from the La Meseta Formation (Eocene) of Seymour Island, Antarctic Peninsula." Polish Polar Research 36, no. 1 (2015): 25–49. http://dx.doi.org/10.1515/popore-2015-0003.

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AbstractThe loose, small zooecia of the cheilostome bryozoans have been discovered in the lowermost part of the LaMeseta Formation on Seymour (Marambio) Island. They systemati− cally include the representatives of Beanidae Canu et Bassler, Catenicellidae Busk, Savi− gnyellidae Levinsen, and Calwelliidae MacGillivray. The bryozoan assemblage is comprised of separate, small−sized internal moulds dominated by distinct, boat−shaped zooecia belonging to Beania, scarce, unizooidal internodes tentatively included into a ditaxiporine catenicellid ?Vasignyella, and representative of the family Savignye

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14

Robertson, Mary L. "Profit and Purpose in the Development of Thomas Cromwell's Landed Estates." Journal of British Studies 29, no. 4 (1990): 317–46. http://dx.doi.org/10.1086/385964.

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Despite the very considerable scholarly attention focused on Thomas Cromwell in recent decades, surprisingly little is known or written about his private financial affairs and, in particular, about the acquisition and management of his landed estates. His principal but badly outdated biographer, R. B. Merriman, was content with a few sweeping generalizations about immense ill-gotten wealth; the only modern biography devotes to this topic barely two paragraphs; and G. R. Elton, who began and sustains the Cromwellian renaissance, is concerned primarily with the public man.Yet at the time of his

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Jadwiszczak, Piotr, Andrzej GaŹdzicki, and Andrzej Tatur. "Short Note: An ibis-like bird from the Upper La Meseta Formation (Late Eocene) of Seymour Island, Antarctica." Antarctic Science 20, no. 4 (2008): 413–14. http://dx.doi.org/10.1017/s0954102008000977.

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Ibises are a group of medium- to large-sized, mainly wading birds in the family Threskiornithidae (Aves: Ciconiiformes; see also discussion in Mayr 2002). They are known from all the continents except Antarctica, though one species breeds as far south as Tierra del Fuego (del Hoyoet al.1992, p. 499). The oldest fossil bones (including skull elements) attributed to ibises are those ofRhynchaeites messelensisWittich, 1898 from the Middle Eocene of Messel, Germany (Peters 1983, Mayr 2002). Another supposed member of this group is the Pondaung bird from the late Middle Eocene of Myanmar (formerly

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CHEVEREȘAN, Cristina. "“Goodbye, Americana, Hello Real Time”: The Death of Idealism in Philip Roth’s American Pastoral." Studia Universitatis Babeș-Bolyai Philologia 69, no. 3 (2024): 101–20. http://dx.doi.org/10.24193/subbphilo.2024.3.06.

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“Goodbye, Americana, Hello Real Time”: The Death of Idealism in Philip Roth’s American Pastoral. Philip Roth’s 1997 American Pastoral is a textbook illustration of failed cultural transmission: the transference and transformation of values, idea(l)s and information in the lives of Seymour Levov, his family, his community prove to be governed by loss, misrepresentation and gradual decline into disorder. Far from delivering the romanticized version of life in the Jewish neighborhood that the title implies, the novel captures a disenchanted Americana, wherein idealism and radicalism clash against

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17

George, Ivy. "BOOK REVIEW: Catherine Weinberger-Thomas. ASHES OF IMMORTALITY. and Susan C. Seymour. WOMEN, FAMILY, AND CHILD CARE IN INDIA IN TRANSITION." NWSA Journal 13, no. 1 (2001): 179–83. http://dx.doi.org/10.2979/nws.2001.13.1.179.

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18

Gelfo, Javier N., Guillermo M. López, and Sergio N. Santillana. "Eocene ungulate mammals from West Antarctica: implications from their fossil record and a new species." Antarctic Science 29, no. 5 (2017): 445–55. http://dx.doi.org/10.1017/s0954102017000244.

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AbstractHere we describe a new terrestrial mammal from the Eocene of Seymour Island (Isla Marambio) represented by a lower left third molar and assigned to a new species of Sparnotheriodontidae, an ungulate family with a broad palaeobiogeographical distribution in South America. The specimen was found in the Cucullaea I allomember of the La Meseta Formation, in a new mammalian locality (IAA 2/16). Notiolofos regueroi sp. nov. shares a brachyodont, lophoselenodont and bicrescentic molar pattern with N. arquinotiensis, recorded for a stratigraphic sequence of 17.5 Ma in Antarctica. The criteria

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STILWELL, JEFFREY D. "A new species of Calliotropis (Mollusca: Gastropoda: Vetigastropoda: Trochidae: Eucyclinae) from the Eocene of Antarctica." Molluscan Research 25, no. 1 (2005): 9–13. http://dx.doi.org/10.11646/mr.25.1.2.

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Trochid gastropods represent an important, diverse family in the Eocene fossil record of Antarctica with no fewer than eight recorded species, one newly described herein. The discovery of Calliotropis antarchais n. sp. (Eucyclinae) in Telm5 (Unit V) of the La Meseta Formation (mid-Eocene Epoch, ca. 45-50 Ma) on Seymour Island, Antarctica Peninsula, marks not only the sole occurrence of this group in the Antarctic fossil record, but further displays the pronounced plasticity of form typical in extant taxa. The new species, an inferred deposit feeder, inhabited very shallow, subtidal waters in s

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Long, Douglas J. "Quaternary colonization or Paleogene persistence?: historical biogeography of skates (Chondrichthyes: Rajidae) in the Antarctic ichthyofauna." Paleobiology 20, no. 2 (1994): 215–28. http://dx.doi.org/10.1017/s0094837300012690.

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Seven endemic species of skates (Chondrichthyes: Rajidae) represent the only family of elasmobranchs currently known to live in Antarctic continental waters. Many previous authors believed skates colonized Antarctic waters from Patagonia during interglacial periods in the Quaternary. However, recent fossil material collected from the middle Eocene La Meseta Formation of Seymour Island, Antarctic Peninsula, indicates that they may have persisted in Antarctic waters since the Paleogene. Additionally, oceanographic barriers present in the Neogene and Quaternary would have prevented dispersal from

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Clayton, Carmen Lau. "Displaying Families: A New Concept for the Sociology of Family LifeBy Esther Dermott and Julie Seymour Basingstoke: Palgrave Macmillan, 2011 ISBN 978-0-230-24613-3, 231 pp, £55 (hardback)." Children & Society 27, no. 1 (2012): 77–78. http://dx.doi.org/10.1111/j.1099-0860.2012.00469.x.

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22

Snyder, M. D., J. H. Pryor, K. J. Veazey, et al. "195 SUPPRESSION OF SETDB1 DURING BOVINE EMBRYONIC DEVELOPMENT RESULTS IN PRE-IMPLANTATION MORTALITY AND DECREASED TRANSCRIPTION OF TRANSPOSABLE ELEMENTS." Reproduction, Fertility and Development 27, no. 1 (2015): 188. http://dx.doi.org/10.1071/rdv27n1ab195.

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Organization of chromatin structure by the combinatorial patterns of DNA methylation and post-translational histone modification is essential for the establishment and maintenance of proper transcriptional programs that result in the coordination of embryonic development. We previously observed that suppression of transcripts encoding SET domain, bifurcated 1 (SETDB1) using small interfering RNAs (siRNA) is embryonic lethal, with SETDB1-suppressed embryos (n = 361) arresting immediately before the blastocyst stage (blastocyst rate: Control 44.9 ± 4.9% and NULL injected 25.7 ± 6.0%). Studies in

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Brustur, Ioana Camelia. "Instances of fame in postmodern fictional works an analysis based on Philip Roth’s and Marin Preda’s novels." Swedish Journal of Romanian Studies 6, no. 1 (2023): 268–82. http://dx.doi.org/10.35824/sjrs.v6i1.24896.

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This article will discuss multiple instances of fame in postmodern fictional works. The authors chosen are Philip Roth, the American author well known for works such as “I Married a Communist”, “The Human Stain”, “The Dying Animal” etc. and Marin Preda, the Romanian author who wrote “The Moromete Family”, “The Intruder”, “The Delirium”. The novels representing the postmodern literary current in this article “merican Pastoral (1997)” and “The Most Beloved of Earthlings (1980)”. Through a close analysis of the main characters and the most important events in the novel, the theme of fame will be

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Weitzel, Jeffrey N., Julio Abugattas, Cynthia Villarreal-Garza, et al. "Abstract P039: Framework for genomic cancer risk assessment dissemination and implementation in Latin America: The GRACIAS (genetic risk assessment for cancer implementation and sustainment) study." Cancer Prevention Research 16, no. 1_Supplement (2023): P039. http://dx.doi.org/10.1158/1940-6215.precprev22-p039.

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Abstract Introduction: Lack of public insurance coverage for genetic testing and a limited trained genomic cancer risk assessment (GCRA) workforce are barriers to cancer screening and prevention and to understanding the genetic epidemiology of cancer in low/middle income countries (LMIC) in Latin America. Methods: We implemented an intervention that included professional education for clinicians in Mexico, Peru and Colombia, support from a community of practice and a federated consortium of collaborators, a versatile research registry with a dual purpose (research and clinical care) centralize

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Del Poeta, Giovanni, Maria Ilaria Del Principe, Michele Dal Bo, et al. "Clinical Significance of Apoptosis in Chronic Lymphocytic Leukemia (CLL)." Blood 124, no. 21 (2014): 834. http://dx.doi.org/10.1182/blood.v124.21.834.834.

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Abstract Impaired programmed cell death is an important factor both in the pathogenesis of CLL (Berndt et al, Nat Genet 2013) and in the development of resistance to chemoimmunotherapy (Fegan et al, Adv Exp Med Biol 2013). It has become increasingly clear that in CLL the balance between the pro- (Bax) and anti-apoptotic members (Bcl-2) of the Bcl-2 family determines the chemotherapy sensitivity and ultimately progression free (PFS) and overall survival (OS). Moreover, the today availability in clinical use of novel potent oral pro-apoptotic BH3 peptidomimetics such as ABT 199 (Seymour et al, A

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Wang, Haitao, Qiming Zhou, Lin Li, et al. "Bgb-16673, a Selective BTK Degrader, Exhibits Deeper Inhibition of Cancer Cell Signaling Pathways and Better Efficacy in MCL Models." Blood 144, Supplement 1 (2024): 5833. https://doi.org/10.1182/blood-2024-202909.

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Introduction: Cell cycle dysregulation, B cell receptor (BCR) signaling, and constitutive NFκB activation are key aberrations in the pathogenesis of mantle cell lymphoma (MCL) (Jain and Wang, 2022). BCR signaling is crucial for the proliferation, survival, and migration of lymphoma cells, with BTK, a non-receptor protein kinase, playing a pivotal role (Young and Staudt, 2013). Over the past decade, the development and approval of covalent BTK inhibitors (cBTKis) like ibrutinib, acalabrutinib, and zanubrutinib, as well as the non-covalent BTK inhibitor (ncBTKi) pirtobrutinib, have marked substa

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Klembara, Jozef. "The cranial anatomy of Discosauricsus Kuhn, a seymouriamorph tetrapod from the Lower Permian of the Boskovice Furrow (Czech Republic)." Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 352, no. 1351 (1997): 257–302. http://dx.doi.org/10.1098/rstb.1997.0021.

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A detailed description is given of the cranial anatomy of the Lower Permian tetrapod Discosauriscus . This material is three–dimensionally preserved and represents one of the best know seymouriamorph tetrapods. Two species, D. austriacus and D. pulcherrimus , are distinguished in the material from the Boskovice Furrow. D. austriacus is abundant, D. pulcherrimus is rare. The two species differ in the following features: (1) the shape of the postorbital and the jugal and the nature of their junction; (2) the shape of the prefrontal and the postfrontal and the position of their contact; and (3) t

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Weitzel, Jeffrey N., Yanin Chavarri-Guerra, Ana Ferrigno, et al. "Abstract 2214: Disparity in the uptake of risk-reducing surgery after GCRA in Hispanic patients in Latin America and in the United States." Cancer Research 82, no. 12_Supplement (2022): 2214. http://dx.doi.org/10.1158/1538-7445.am2022-2214.

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Abstract Background: Patients at increased risk of breast (BC) and/or ovarian (OC) cancer can opt for risk-reducing surgeries (RRS). However, there are disparities in access to genomic cancer risk assessment (GCRA) and cancer prevention interventions related to geography, socioeconomic status, and limited public health support. We studied factors that affect the uptake of risk-reducing mastectomy (RRM) and salpingo-oophorectomy (RRSO) in Hispanic patients of Latin America (LatAm) and the United States (US). Methods: Hispanic women enrolled in the Clinical Cancer Genomics Community Research Net

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Kvenvold, Laura, Caroline Frost, Grace Hong, Ian Michelow, and Jennifer Girotto. "Inpatient Penicillin Allergy Delabeling by Direct Oral Challenge at a Free-standing Children’s Hospital in Connecticut." Journal of the Pediatric Infectious Diseases Society 13, Supplement_3 (2024): S15. https://doi.org/10.1093/jpids/piae088.028.

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Abstract Corresponding Author: Laura Kvenvold, MD No Conflicts, Pediatric Infectious Diseases and Immunology, Connecticut Children’s Medical Center, Hartford, Connecticut, USA, Department of Infectious Diseases, University of Connecticut School of Medicine, Farmington, Connecticut, USA, Tele: 978-328-6646, Address: CCMC Infectious Diseases, 85 Seymour St, Suite 816, Hartford, CT, 06106, Email: lkvenvold@connecticutchildrens.org, kvenvold@uchc.edu Dr. Girotto has received unrestricted grant funds from Pfizer and is a consultant for Lexi Comp Background In the United States, approximately 10% of

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Pocock, Lucy, Fiona MacKichan, Francesca Deibel, and Lesley Wye. "34 Stories from the fourth age." BMJ Supportive & Palliative Care 7, no. 3 (2017): A360.1—A360. http://dx.doi.org/10.1136/bmjspcare-2017-001407.34.

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IntroductionMost older care home residents will die in the care home environment. The majority of older people would like the opportunity to discuss end-of-life care, though this rarely happens. The current model of palliative care does not cater well for care home residents.This study explores the narratives shared by older people living in care homes.Aims1. What are the issues facing elderly people in the last years of life?2. What are the key events that shape this phase and how do their interactions and relationships with carers, healthcare professionals, family and friends affect this?Met

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Damsté, P. H. "De geschiedenis van het portret van Jaspar Schade door Frans Hals1." Oud Holland - Quarterly for Dutch Art History 99, no. 1 (1985): 30–42. http://dx.doi.org/10.1163/187501785x00035.

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AbstractOnly a few weeks after seeing the Frans Hals portrait of Jaspar Schade in the 1962 exhibition in Haarlem, the author came upon it again in the home of Mr. and Mrs. Waller in Utrecht (Figs. 1 and 2, Note I). He learnt that this particular painting had been in Mr. Waller's family for nearly a century and that it was a copy of the one now in Prague. The story was that the latter had been sold by Mr. Waller's grandfather Beukerfrom his country-house 'Zandbergen', which he had bought in 1865, to his friend P.E.H. Praetorius, on condition that the latter had a copy painted as a replacement.

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Powers, Thomas O., Peter Mullin, Rebecca Higgins, Timothy Harris, and Kirsten S. Powers. "Description of Mesocriconema ericaceum n. sp. (Nematoda: Criconematidae) and notes on other nematode species discovered in an ericaceous heath bald community in Great Smoky Mountains National Park, USA." Nematology 18, no. 8 (2016): 879–903. http://dx.doi.org/10.1163/15685411-00003001.

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A new species of Mesocriconema and a unique assemblage of plant-parasitic nematodes was discovered in a heath bald atop Brushy Mountain in Great Smoky Mountains National Park. Mesocriconema ericaceum n. sp., a species with males, superficially resembles M. xenoplax. DNA barcoding with the mitochondrial COI gene provided evidence of the new species as a distinct lineage. SEM revealed significant variability in arrangement of labial submedian lobes, plates, and anterior and posterior annuli. Three other nematodes in the family Criconematidae were characterised from the heath bald. Ogma seymouri,

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Davids, Matthew S., Jing Deng, Jeremy Ryan, Stacey M. Fernandes, Jennifer R. Brown, and Anthony G. Letai. "Mitochondrial Apoptotic Priming Is Associated with Clinical Response to the Bcl-2 Antagonist ABT-199 in Chronic Lymphocytic Leukemia." Blood 124, no. 21 (2014): 1940. http://dx.doi.org/10.1182/blood.v124.21.1940.1940.

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Abstract BACKGROUND: BH3 profiling is a functional assay that assesses the degree to which cells are primed to die via mitochondrial apoptosis. We previously used this technique to show that pre-treatment CLL cells from patients who responded to frontline chemoimmunotherapy had higher levels of apoptotic priming than cells from refractory patients (Davids et al., Blood, 2012). BH3 profiling also detects dependence on individual anti-apoptotic Bcl-2 family proteins. Recently, ABT-199, a selective, potent, small molecule antagonist of the anti-apoptotic protein Bcl-2, has been found to be highly

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SANTOS, A. L. S., C. M. ABREU, C. S. ALVIANO, and R. M. A. SOARES. "Use of proteolytic enzymes as an additional tool for trypanosomatid identification." Parasitology 130, no. 1 (2004): 79–88. http://dx.doi.org/10.1017/s0031182004006353.

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The expression of proteolytic activities in the Trypanosomatidae family was explored as a potential marker to discriminate between the morphologically indistinguishable flagellates isolated from insects and plants. We have comparatively analysed the proteolytic profiles of 19 monoxenous trypanosomatids (Herpetomonas anglusteri,H. samuelpessoai,H. mariadeanei,H. roitmani,H. muscarum ingenoplastis,H. muscarum muscarum,H. megaseliae,H. dendoderi,Herpetomoassp.,Crithidia oncopelti,C. deanei,C. acanthocephali,C. harmosa,C. fasciculata,C. guilhermei,C. luciliae,Blastocrithidia culicis,Leptomonas sam

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Sereno, Denis, Franck Dorkeld, Mohammad Akhoundi, and Pascale Perrin. "Pathogen Species Identification from Metagenomes in Ancient Remains: The Challenge of Identifying Human Pathogenic Species of Trypanosomatidae via Bioinformatic Tools." Genes 9, no. 8 (2018): 418. http://dx.doi.org/10.3390/genes9080418.

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Accurate species identification from ancient DNA samples is a difficult task that would shed light on the evolutionary history of pathogenic microorganisms. The field of palaeomicrobiology has undoubtedly benefited from the advent of untargeted metagenomic approaches that use next-generation sequencing methodologies. Nevertheless, assigning ancient DNA at the species level is a challenging process. Recently, the gut microbiome analysis of three pre-Columbian Andean mummies (Santiago-Rodriguez et al., 2016) has called into question the identification of Leishmania in South America. The accurate

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Aisyah Durrotun Nafisah, Yuli Kurniawati Sugiyo Pranoto, and Siti Nuzulia. "The Impact of Father Involvement in the Early Childhood Problematic Behavior." JPUD - Jurnal Pendidikan Usia Dini 17, no. 1 (2023): 14–30. http://dx.doi.org/10.21009/jpud.171.02.

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Father's involvement is something that influences the child's problematic behavior. The purpose of this study is to investigate whether father involvement can influence children's problematic behavior. This study used the systematic literature review (SLR) method by referring to 10 valid articles published in the last 10 years with the publication years between 2013 - 2023. The finding of the literature shows that there is a significant impact of father involvement on the children's problematic behavior. The more the father is involved in the children's development, the lower the level of chil

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Neparidze, Natalia, Krystal W. Lau, Xiaoliang Wang, et al. "Racial Disparities in Telemedicine Uptake during the COVID-19 Pandemic Among Patients with Hematologic Malignancies in the United States." Blood 138, Supplement 1 (2021): 1973. http://dx.doi.org/10.1182/blood-2021-153787.

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Abstract Background/objectives: The COVID-19 pandemic impacted healthcare visit trends, propelling healthcare systems to reduce in-person visits and hospital admissions and increasingly rely on telemedicine; whether there are differences in these trends across racial groups is unknown. This study investigated potential racial disparities in visits during the pandemic for patients with documented active treatment for hematologic malignancies. Methods: We used the nationwide Flatiron Health electronic health record (EHR)-derived de-identified database to select patients with confirmed diagnosis

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Goyal, Gaurav, Krystal W. Lau, Xiaoliang Wang, et al. "Impact of the COVID-19 Pandemic on in-Person Visit Rates Among Patients with Hematologic Malignancies in the United States." Blood 138, Supplement 1 (2021): 1930. http://dx.doi.org/10.1182/blood-2021-153625.

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Abstract Background/objectives: The COVID-19 pandemic led to a dramatic reduction of in-person medical care in the general population; however, impacts have not been well-characterized for patients with hematologic malignancies. This study assessed the impact of COVID-19 on healthcare delivery for patients with hematologic malignancies with documented active treatment. Methods: Patients from the nationwide Flatiron Health electronic health record (EHR)-derived de-identified database with confirmed diagnosis of AML, DLBCL, FL, MCL, CLL or MM, and age ≥ 18 years at initial diagnosis were include

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Seymour, Erlene K., Yiwei Li, Amro Aboukameel, et al. "Selinexor in Combination with R-CHOP for Frontline Treatment of Non-Hodgkin Lymphoma: Results of a Phase 1b Study." Blood 136, Supplement 1 (2020): 11–12. http://dx.doi.org/10.1182/blood-2020-140752.

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Introduction: The chemoimmunotherapeutic regimen of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) is curative for many patients (pts) with diffuse large B cell lymphoma (DLBCL), but a subset of high-risk pts, including those with transformed and double-hit lymphomas, are less likely to be cured by R-CHOP. Exportin-1 (XPO1), a nuclear export protein, is overexpressed in NHL and correlates with chemotherapy-resistance and poor prognosis. Overexpression of XPO1 results in increased nuclear export of tumor suppressor proteins (TSPs) leading to their functional inac

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Kater, Arnon P., Jenny Qun Wu, Julie Dubois, et al. "Genome and Exome-Wide Studies Reveal Potential Predictive Efficacy Markers for Venetoclax and Rituximab (VenR) in Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL): Subgroup Analyses of the Murano Trial." Blood 134, Supplement_1 (2019): 356. http://dx.doi.org/10.1182/blood-2019-123678.

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The first two authors contributed equally. Introduction: VenR (2 years of Ven, plus R during the first 6 months) improved progression-free/overall survival (PFS/OS) vs bendamustine + R (BR) in patients (pts) in with R/R CLL in MURANO (Seymour et al. N Eng J Med 2018). MURANO also showed early, sustained and durable undetectable minimal residual disease (uMRD) status with VenR, which is associated with prolonged survival in CLL (Kater et al. J Clin Oncol 2019). Here we explore associations between baseline molecular characteristics and VenR-induced MRD responses and PFS based on the 4-year foll

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Seymour, John F., Jenny Qun Wu, Relja Popovic, et al. "Assessment of the Clonal Dynamics of Acquired Mutations in Patients (Pts) with Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL) Treated in the Randomized Phase 3 Murano Trial Supports Venetoclax-Rituximab (VenR) Fixed-Duration Combination Treatment (Tx)." Blood 138, Supplement 1 (2021): 1548. http://dx.doi.org/10.1182/blood-2021-147731.

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Abstract Introduction: In the MURANO trial (NCT02005471), fixed-duration VenR (2 yrs Ven + R for the first 6 mo) improved survival and rates of undetectable minimal residual disease (MRD) over bendamustine (Benda)-R in pts with R/R CLL. Novel recurrent mutations in BCL2 and family genes (eg BAX and PMAIP1 [encoding Noxa]) have been linked to Ven resistance. We analyzed MRD+ samples from VenR-treated pts in MURANO to assess the nature and frequency of acquired mutations in BCL2 family genes (marker of emergent Ven resistance) and TP53 (may negatively impact response to re-Tx). We also analyzed

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Кючуков Хрісто and Віллєрз Джіл. "Language Complexity, Narratives and Theory of Mind of Romani Speaking Children." East European Journal of Psycholinguistics 5, no. 2 (2018): 16–31. http://dx.doi.org/10.29038/eejpl.2018.5.2.kyu.

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The paper presents research findings with 56 Roma children from Macedonia and Serbia between the ages of 3-6 years. The children’s knowledge of Romani as their mother tongue was assessed with a specially designed test. The test measures the children’s comprehension and production of different types of grammatical knowledge such as wh–questions, wh-complements, passive verbs, possessives, tense, aspect, the ability of the children to learn new nouns and new adjectives, and repetition of sentences. In addition, two pictured narratives about Theory of Mind were given to the children. The hypothes

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Basavaraju, Manu, L. Sunil Chandran, Mathew C. Francis, and Karthik Murali. "Variants of the Gyárfás–Sumner conjecture: Oriented trees and rainbow paths." Journal of Graph Theory, September 10, 2024. http://dx.doi.org/10.1002/jgt.23171.

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AbstractGiven a finite family of graphs, we say that a graph is “‐free” if does not contain any graph in as a subgraph. We abbreviate ‐free to just “‐free” when . A vertex‐colored graph is called “rainbow” if no two vertices of have the same color. Given an integer and a finite family of graphs , let denote the smallest integer such that any properly vertex‐colored ‐free graph having contains an induced rainbow path on vertices. Scott and Seymour showed that exists for every complete graph . A conjecture of N. R. Aravind states that . The upper bound on that can be obtained using the methods o

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Fijavž, Gašper, and David R. Wood. "Graph Minors and Minimum Degree." Electronic Journal of Combinatorics 17, no. 1 (2010). http://dx.doi.org/10.37236/423.

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Let $\mathcal{D}_k$ be the class of graphs for which every minor has minimum degree at most $k$. Then $\mathcal{D}_k$ is closed under taking minors. By the Robertson-Seymour graph minor theorem, $\mathcal{D}_k$ is characterised by a finite family of minor-minimal forbidden graphs, which we denote by $\widehat{\mathcal{D}}_k$. This paper discusses $\widehat{\mathcal{D}}_k$ and related topics. We obtain four main results: We prove that every $(k+1)$-regular graph with less than $\frac{4}{3}(k+2)$ vertices is in $\widehat{\mathcal{D}}_k$, and this bound is best possible. We characterise the graph

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van Batenburg, Wouter Cames, Tony Huyn, Gwenaël Joret, and Jean-Florent Raymond. "A tight Erdős-Pósa function for planar minors." Advances in Combinatorics, October 30, 2019. http://dx.doi.org/10.19086/aic.10807.

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Let F be a family of graphs. Then for every graph G the maximum number of disjoint subgraphs of G, each isomorphic to a member of F, is at most the minimum size of a set of vertices that intersects every subgraph of G isomorphic to a member of F. We say that F packs if equality holds for every graph G. Only very few families pack. As the next best weakening we say that F has the Erdős-Pósa property if there exists a function f such that for every graph G and integer k>0 the graph G has either k disjoint subgraphs each isomorphic to a member of F or a set of at most f(k) vertices that inters

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Esperet, Louis, Ugo Giocanti, and Clément Legrand-Duchesne. "The structure of quasi-transitive graphs avoiding a minor with applications to the domino problem." European Conference on Combinatorics, Graph Theory and Applications, no. 12 (August 28, 2023). http://dx.doi.org/10.5817/cz.muni.eurocomb23-059.

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An infinite graph is quasi-transitive if its vertex set has finitely many orbits under the action of its automorphism group. In this paper we obtain a structure theorem for locally finite quasi-transitive graphs avoiding a minor, which is reminiscent of the Robertson-Seymour Graph Minor Structure Theorem. We prove that every locally finite quasi-transitive graph $G$ avoiding a minor has a tree-decomposition whose torsos are finite or planar; moreover the tree-decomposition is canonical, i.e. invariant under the action of the automorphism group of $G$. As applications of this result, we prove t

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Hatzel, Meike, Pawel Komosa, Marcin Pilipczuk, and Manuel Sorge. "Constant Congestion Brambles." Discrete Mathematics & Theoretical Computer Science 24, no. 1, Graph Theory (2022). http://dx.doi.org/10.46298/dmtcs.6699.

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A bramble in an undirected graph $G$ is a family of connected subgraphs of $G$ such that for every two subgraphs $H_1$ and $H_2$ in the bramble either $V(H_1) \cap V(H_2) \neq \emptyset$ or there is an edge of $G$ with one endpoint in $V(H_1)$ and the second endpoint in $V(H_2)$. The order of the bramble is the minimum size of a vertex set that intersects all elements of a bramble. Brambles are objects dual to treewidth: As shown by Seymour and Thomas, the maximum order of a bramble in an undirected graph $G$ equals one plus the treewidth of $G$. However, as shown by Grohe and Marx, brambles o

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Klembara, Jozef. "The Cranial Anatomy of Discosauriscus Kuhn, a Seymouriamorph Tetrapod from the Lower Permian of the Boskovice Furrow (Czech Republic)." March 29, 1997. https://doi.org/10.1098/rstb.1997.0021.

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A detailed description is given of the cranial anatomy of the Lower Permian tetrapod Discosauriscus. This material is three-dimensionally preserved and represents one of the best known seymouriamorph tetrapods. Two species, D. austriacus and D. pulcherrimus, are distinguished in the material from the Boskovice Furrow. D. austriacus is abundant, D. pulcherrimus is rare. The two species differ in the following features: in (1) the shape of the postorbital and the jugal and the nature of their junction, (2) the shape of the prefrontal and the postfrontal and the position of their contact and (3)

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Leavitt, Linda. "Searching for the Real: ‘Family Business,’ Pornography, and Reality Television." M/C Journal 7, no. 4 (2004). http://dx.doi.org/10.5204/mcj.2386.

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Showtime’s reality TV series Family Business opens with a black screen and audio: the whirring of a 16mm projector, the home movies of a generation ago. The sound connotes nostalgia, memory, family, and film. In my childhood, the sound of the projector meant family time, a glance back at our toddler years, the years of Sunday dinners in the suburbs, when my mother and all my aunts still smoked. Later, as my sister and cousins whose childhoods are fixed in that celluloid began to date and marry, family movies were a means of introducing the soon-to-be-married other into the family; this was how

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Eaton, Oline. "A “very politically correct, wholesome family show”: Jane Seymour’s white, heterosexual femininity in Dr. Quinn, Medicine Woman." TV/Series, no. 20 (April 27, 2022). http://dx.doi.org/10.4000/tvseries.5789.

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