Academic literature on the topic 'Sharer (free holder)'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Sharer (free holder).'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Sharer (free holder)"
1
Murifal, Badar. "Free Cash Flow Analysis Indikator Bagi Investor dalam Mengukur Pertumbuhan Keuangan Perusahaan." Ekonomis: Journal of Economics and Business 4, no. 2 (September 1, 2020): 279. http://dx.doi.org/10.33087/ekonomis.v4i2.157.
Full textAbstract:
Free Cash Flow, often abbreviate FCF, is an efficiency and liquidity ratio that calculates the how much more cash a company generates than it uses to run and expand the business by subtracting the capital expenditures from the operating cash flow. In other words, this is the excess money a business produces after it pays all of its operating expenses and CAPEX. This is an important concept because it shows how efficient the business is at generating cash and if it can pay its investors a return after it funds its operations and expansions. FCF is an important measurement since it shows how efficient a company is at generating cash. Investors use free cash flow to measure whether a company might have enough cash, after funding operations and capital expenditures, to pay investors through dividends and share buybacks.in corporate finance free vash flow is a way of looking at a business’s cash flow to see what is available for distribution among all the securities holders of a corporate entity. FCF is the amount of cash that a company cabn put aside after it has paid all of its expenses at the end of an accounting periode. It is often evaluated on a per share basis to evaluate the effect of dilution. Reveal a problem in the fundamentals before they arise on the income statement.
2
Godfrey, Sosheel S., Gavin C. Ramsay, Karl Behrendt, Peter C. Wynn, Thomas L. Nordblom, and Naveed Aslam. "Analysis of agribusiness value chains servicing small-holder dairy farming communities in Punjab, Pakistan: three case studies." International Food and Agribusiness Management Review 22, no. 1 (January 28, 2019): 119–36. http://dx.doi.org/10.22434/ifamr2017.0122.
Full textAbstract:
The agriculture sector in Pakistan, as in most developing countries, is dominated by smallholder producers. Pakistan has the world’s third largest dairy industry, and milk is efficiently collected and distributed chiefly by informal value chains that market the raw product with minimal cool chain infrastructure. Formal processors have a small market share of 5%. Interview data from farmers, milk collectors and consumers from three rural-urban case study value chains were analysed to study opportunities and challenges faced by the dairy industry. Compositional analysis of milk samples (n=84) collected along these chains identified the fact that in Pakistan informal milk chains provide a cheaper source of calories for the final consumer than industrialised milk chains (USD 0.12 compared USD 0.15 per 100 calories). These three chains created an estimated 4,872 jobs from farm to market and provided access to interest-free credit for the farmers. The existing government price setting mechanism at the retail end and collusion by large processors to set farm gate prices provided significant limitations to the profitability of small-holder farms providing the product. The absence of quality and quantity standards, amid the exchange of huge numbers of small volumes of milk along these chains, are major impediments to industry growth.
3
Islam, K. M. Anwarul. "An Empirical Research on Beximco Knitting Ltd: Ratio, DuPont, Valuation and Pro-Forma Analysis." Indian Journal of Finance and Banking 1, no. 1 (July 17, 2017): 1–7. http://dx.doi.org/10.46281/ijfb.v1i1.80.
Full textAbstract:
Beximco Knitting Ltd belongs to the Textile Industry. This paper examines some ratio analysis that showed the overall internal liquidity position of the company, that is not satisfactory; because of the entire ratio performance is not good, operating efficiency ratio is not good, indicates that lower efficiency generate capacity in terms of sale, debt-equity ratio is increasing overtime in order to employ the more debt financing as long-term borrowing compare to the equity financing, which make the firm more risky. Beximco Knitting Ltd is more sensitive to leverage compare to net profit margin and Asset turnover Discounted Cash Flow Analysis Model is using for valuation of the Beximco Knitting Ltd‘s prospective analysis. Forecasting the cash flow we have to use 2016-2017 as the base year of foresting cash flow for 2018-2020.The terminal growth rate of free cash flow is 2% and the present value of free cash flow is arrived using the 'Exit Multiple' model.Free cash flow to equity is discounted 10.77% to arrive at an estimated present value of free cash flows available to equity (debt and equity holders as a group), which is also known as Enterprise Value. Equity value per share (142.07) on the other hand, the market price of Beximco Knitting is 47.5tk per share, which indicates the share price is undervalued. Under pro-forma analysis we find out that all items of the financial statement is improving based on the assumption, but as investor‘s perspective we think investing in that company is not beneficial over the long run.Because the company can‘t earn positive return until 2020. Findings of the artcle are to really negative signs in accordance the investor‘s perspective, because its earnings per share are not attractive as much to invest.
4
Ryan, Kellie, Hannah Le, Svea K. Wahlstrom, Kathleen Beusterien, Oliver Will, Martine C. Maculaitis, and Thomas W. Leblanc. "How Do Progression-Free Survival and Toxicity Risks Influence Oncologist and Patient Preferences for Novel Agents in Chronic Lymphocytic Leukemia?" Blood 136, Supplement 1 (November 5, 2020): 52–53. http://dx.doi.org/10.1182/blood-2020-138952.
Full textAbstract:
Introduction: Treatment for chronic lymphocytic leukemia (CLL) has changed with the approval of novel agents, which have different toxicity profiles. The aim of the current analysis was to determine how incremental changes in efficacy and toxicity profile impact treatment selection among patients with CLL and oncologists. Methods: In this US-based study, oncologists and CLL patients completed an online survey that included a discrete choice experiment (DCE) to quantify preferences for first line (1L) treatment with novel agents. Self-reported data on oncologist and patient characteristics were also collected. In the DCE, respondents selected between hypothetical treatment profiles consisting of 8 attributes with varying levels. The attributes were selected based on the findings of qualitative interviews assessing treatment priorities among oncologists and patients. The attribute levels were abstracted from clinical trials and published literature (Table 1). Hierarchical Bayesian regression models were used to estimate preference weights for each attribute level. The preference weights were used to generate a base case hypothetical treatment profile, against which other hypothetical profiles varying in adverse event (AE) risk and 2-year progression-free survival (PFS) were evaluated to understand which attributes and levels drive treatment selection. The overall mean summed preference weight for the collective set of alternative profiles was then compared with the base case, with higher positive values indicating the more preferred profile. Results: Oncologists (N=151) reported a mean of 16.3±7.0 years in practice (Table 2). Most practiced in a community setting (72%) and in a major metropolitan/urban area (64%). Among patients (N=220), median age was 56.0 years, with a mean disease duration of 2.0±3.1 years at time of study (Table 2). Most patients were in or had completed at least 1L therapy (68%). Figure 1 illustrates the impact of changing various attribute levels on the overall preference of an alternative profile, relative to a base case profile. Decreasing 2-year PFS from 95% to 75% (Profile A) and reducing the risks of atrial fibrillation (A-fib) from 20% to 5% (Profile B) and infection from 30% to 7% (Profile C) had the greatest influence on treatment preferences for oncologists when holding all other attribute levels constant. Oncologists preferred the profile with reduced 2-year PFS and reduced risk of AEs (Profile G) to the base case profile, corresponding to a 45% difference in preference share. Similarly, for patients, reducing 2-year PFS from 95% to 75% (Profile A) and reducing the risks of infection from 30% to 7% (Profile C) and A-fib from 20% to 5% (Profile B) were most influential in treatment choice when all other attribute levels were held constant (Figure 1). However, patients preferred the base case profile with higher PFS and higher risk of AEs to Profile G, corresponding to a 38% difference in preference share. Conclusions: For oncologists and patients, decreasing 2-year PFS and reducing the risks of either A-fib or infection had the most influence on 1L treatment preference, relative to the base case in which 2-year PFS was the highest and the AE risks were set to the worst levels reported in literature for novel therapies. The pattern and direction of treatment preferences were generally consistent among oncologists and patients, relative to the base case, across all alternative profiles when individually examined. However, for patients, the positive impact of reducing the risk of AEs was outweighed by the negative impact of reducing PFS. Consequently, all other things being equal, patients preferred a 1L profile with higher PFS even if it came with higher AE risks. In contrast, oncologists were willing to accept a treatment with less efficacy in exchange for the most favorable safety profile. This difference may be due to a patient's lack of understanding of the potential severity of AEs or a physician's lack of awareness of the patient's treatment priorities. This is an area for future research and highlights the importance of oncologists explicitly communicating the known efficacy benefits and AE risks associated with each treatment option because these factors may influence patients' treatment choice in a way that differs from their own. Disclosures Ryan: AstraZeneca: Current Employment, Current equity holder in private company. Le:AstraZeneca: Current Employment, Current equity holder in private company. Wahlstrom:AstraZeneca: Current Employment, Current equity holder in private company. Beusterien:Kantar: Other: Employee of Kantar, which received funding from AstraZeneca to conduct this study. Will:Kantar: Other: Employee of Kantar, which received funding from AstraZeneca to conduct this study. Maculaitis:Kantar: Other: Employee of Kantar, which received funding from AstraZeneca to conduct this study. Leblanc:UpToDate: Patents & Royalties: Royalties; Agios, AbbVie, and Bristol Myers Squibb/Celgene: Speakers Bureau; AstraZeneca: Research Funding; AbbVie, Agios, Amgen, AstraZeneca, CareVive, BMS/Celgene, Daiichi-Sankyo, Flatiron, Helsinn, Heron, Otsuka, Medtronic, Pfizer, Seattle Genetics, Welvie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; American Cancer Society, BMS, Duke University, NINR/NIH, Jazz Pharmaceuticals, Seattle Genetics: Research Funding.
5
Gorbik, K. А. "Activities of the Azov-Don Commercial Bank in the Russian Empire." IZVESTIYA VUZOV SEVERO-KAVKAZSKII REGION SOCIAL SCIENCE, no. 3 (207) (October 19, 2020): 45–49. http://dx.doi.org/10.18522/2687-0770-2020-3-45-49.
Full textAbstract:
The great reforms of Alexander II contributed to the development of a network of state and non-state bank-ing institutions. Non-state credit organizations such as commercial banks not only lent to different sectors of the domestic economy, but also brought financial dividends to the holders of their shares. Commercial banks played the role of intermediaries between persons with free capital and citizens of the Russian Empire who needed additional financial resources. The activities of private bank institutions were aimed at supporting the people of the Russian Empire by providing various banking services. The author explores the activities of commercial banks in the context of the development of capitalist relations in the reformed Russia. The activity of lending to the Don population by central and local commercial banks is considered separately. On the basis of statistical materials, it describes the operations of the Azov-Don commercial bank. The organizational structure of the Azov-Don commercial bank is investigated. Its activity is considered as financial discount, issue of loans and reception of deposits.
6
Barnes, Christopher O., Ying Wu, Jinhu Song, Guowu Lin, Elizabeth L. Baxter, Aaron S. Brewster, V. Nagarajan, et al. "The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity." Proceedings of the National Academy of Sciences 116, no. 19 (April 24, 2019): 9333–39. http://dx.doi.org/10.1073/pnas.1814999116.
Full textAbstract:
Deoxynucleotide triphosphohydrolases (dNTPases) play a critical role in cellular survival and DNA replication through the proper maintenance of cellular dNTP pools. While the vast majority of these enzymes display broad activity toward canonical dNTPs, such as the dNTPase SAMHD1 that blocks reverse transcription of retroviruses in macrophages by maintaining dNTP pools at low levels, Escherichia coli (Ec)-dGTPase is the only known enzyme that specifically hydrolyzes dGTP. However, the mechanism behind dGTP selectivity is unclear. Here we present the free-, ligand (dGTP)- and inhibitor (GTP)-bound structures of hexameric Ec-dGTPase, including an X-ray free-electron laser structure of the free Ec-dGTPase enzyme to 3.2 Å. To obtain this structure, we developed a method that applied UV-fluorescence microscopy, video analysis, and highly automated goniometer-based instrumentation to map and rapidly position individual crystals randomly located on fixed target holders, resulting in the highest indexing rates observed for a serial femtosecond crystallography experiment. Our structures show a highly dynamic active site where conformational changes are coupled to substrate (dGTP), but not inhibitor binding, since GTP locks dGTPase in its apo- form. Moreover, despite no sequence homology, Ec-dGTPase and SAMHD1 share similar active-site and HD motif architectures; however, Ec-dGTPase residues at the end of the substrate-binding pocket mimic Watson–Crick interactions providing guanine base specificity, while a 7-Å cleft separates SAMHD1 residues from dNTP bases, abolishing nucleotide-type discrimination. Furthermore, the structures shed light on the mechanism by which long distance binding (25 Å) of single-stranded DNA in an allosteric site primes the active site by conformationally “opening” a tyrosine gate allowing enhanced substrate binding.
7
Carlson, Josh J., Marita Zimmermann, Audrey Demaree, Tony Hewitt, Benjamin Eckert, and Ajay Nooka. "Cost-Effectiveness of Implementing Clonoseq NGS-MRD Testing Using the Emory MRD Decision Protocol in Multiple Myeloma." Blood 136, Supplement 1 (November 5, 2020): 25–26. http://dx.doi.org/10.1182/blood-2020-143234.
Full textAbstract:
Background: The availability of standardized MRD assessment tools which meet clinical guideline requirements for minimum 10-5 sensitivity have been acknowledged by the International Myeloma Working Group (IMWG) and MRD assessment has been increasingly incorporated into the routine care of multiple myeloma patients. It has been demonstrated that myeloma patients who achieve deep MRD negative status have longer PFS and OS, and NCCN guidelines now recommend assessment for "sustained MRD negativity", defined as two consecutive MRD negative results (10-5, 12 months apart). NGS MRD (clonoSEQ® Assay; Adaptive Biotechnologies) is currently the only FDA cleared MRD test available for patients with MM using bone marrow samples. Several US-based cancer centers have proposed care pathways to leverage NGS MRD assessment to support shared decisions around timing of treatment discontinuation for myeloma patients who have been on indefinite maintenance therapy. It is well known that a more precise approach to maintenance treatment, offering the opportunity for treatment-free observation in patients who have achieved deep sustained MRD negativity, may help to lower costs and improve quality of life. The objective of this study was to evaluate the clinical and economic impact of the hypothesized model for MRD decision framework at Emory which allows for MRD-informed treatment discontinuation. Methods: We evaluated the potential cost effectiveness of the Emory MRD decision framework and projected the associated lifetime/10-year cost-savings for a cohort of patients initiating maintenance therapy within the institution. We leveraged a previously developed Markov model with 6 health states: MRD+ or MRD- on or off therapy (tx), relapsed, or dead and compared yearly NGS MRD to no MRD testing over a lifetime horizon. Based on longitudinal data from Emory (Abstract submitted at ASH 2020), we estimated an annual probability of achieving sustained MRD negativity (i.e. <10-5 across two assessments at least 12 months apart) of 21% while on maintenance treatment. Under that framework, these patients would discontinue treatment and continue to be observed. We assumed annual NGS MRD testing. Progression free survival (PFS) and overall survival (OS) data for MRD- and MRD+ and hazard ratios for on/off tx were applied based on peer-reviewed literature. MRD- pts were assumed to have the same PFS/OS rates on and off tx, which were varied in sensitivity analyses. Health state utilities were based on peer reviewed literature and included an adverse event (AE) disutility. Based on institutional data (Joseph et al JCO 2020), it was assumed that 198 patients would initiate maintenance treatment under this pathway this year. The cost of NGS MRD was $1,950, lenalidomide-based maintenance tx was $21,364/month, and tx for relapsed pts at $29,798/month based on list prices, wholesale acquisition costs, and peer reviewed literature, respectively. We used a US health system perspective and a 3% discount rate. We performed one way and probabilistic sensitivity analysis to characterize the impact of uncertainty in model inputs on model results. Results: For this cohort of patients, MRD testing provided estimated lifetime savings of $916,000 per patient and $181,000,000 for an annual cohort or patients at Emory. Health outcomes were slightly improved for MRD testing vs no testing (0.009 QALYs) due to avoidance of adverse events, suggesting a potentially dominant strategy. This result was most sensitive to the probability of MRD+ to MRD- transition and the cost of maintenance tx. Conclusion: The proposed MRD decision framework is estimated to save costs and potentially improve health outcomes for patients initiating maintenance treatment. Ongoing clinical studies, including planned real-world observation of patients managed via this care pathway will help to fully characterize the long-term health outcomes of MRD testing during MM maintenance tx. Figure 1 Disclosures Carlson: Adaptive Biotechnologies: Consultancy. Zimmermann:Adaptive Biotechnologies: Consultancy. Demaree:Adaptive Biotechnologies: Current Employment, Current equity holder in publicly-traded company. Hewitt:Adaptive Biotechnologies: Current Employment, Current equity holder in publicly-traded company. Eckert:Adaptive Biotechnologies: Current Employment, Current equity holder in publicly-traded company. Nooka:Amgen: Consultancy, Honoraria, Research Funding; Bristol-Myers Squibb: Consultancy, Honoraria, Research Funding; Karyopharm Therapeutics, Adaptive technologies: Consultancy, Honoraria, Research Funding; Spectrum Pharmaceuticals: Consultancy; Adaptive Technologies: Consultancy, Honoraria; Takeda: Consultancy, Honoraria, Research Funding; Celgene: Consultancy, Honoraria, Research Funding; Oncopeptides: Consultancy, Honoraria; GlaxoSmithKline: Consultancy, Honoraria, Other: Personal Fees: Travel/accomodations/expenses, Research Funding; Janssen: Consultancy, Honoraria, Research Funding; Sanofi: Consultancy, Honoraria.
8
Faisal, Faisal, Dani Amran Hakim, and Is Susanto. "CREATIVE COMMONS LICENSE SEBAGAI HAK CIPTA INTERNASIONAL DITINJAU BERDASARKAN ASPEK HUKUM INDONESIA." Jurnal Hukum dan Kenotariatan 5, no. 2 (May 27, 2021): 218. http://dx.doi.org/10.33474/hukeno.v5i2.10186.
Full textAbstract:
Perkembangan teknologi khususnya internet telah mempermudah masyarakat untuk mengakses dan mendistribusikan informasi. Namun, kegiatan seperti copy-cut-paste (menyalin-memotong-menempel), menyunting (editing) ataupun berbagi dokumen (file sharing) justru menimbulkan hal kontradiktif terhadap hukum hak cipta. Berdasarkan hal tersebut tahun 2002 sebuah organisasi nirlaba membuat inovasi dan terobosan yang memungkinkan berbagi dan menggunakan kreativitas dan pengetahuan melalui alat hukum gratis. Metode penelitian yang digunakan dalam tulisan ini adalah metode penelitian yuridis normatif dengan fokus pada pendekatan perundang-undangan dan analisis konten. Berdasarkan analisis pembahasan creative commons bukanlah alternatif dari hukum hak cipta, melainkan bekerja berdampingan dan mampu membuat pencipta/pemegang hak cipta memodifikasi haknya ke dalam keadaan yang paling sesuai dengan kebutuhan. Lisensi creative commons di Indonesia penggunaannya dimungkinkan menurut Pasal 9 ayat (1) Undang-Undang Nomor 28 Tahun 2014 tentang Hak Cipta. Lalu pemegang hak berdasarkan Pasal 81 UU Hak Cipta, dapat mengumumkan dan/atau berhak memberikan lisensi kepada pihak lain berdasarkan perjanjian lisensi untuk melaksanakan perbuatan sebagaimana dimaksud dalam Pasal 9 ayat (1), memperbanyak ciptaannya/produk hak terkaitnya dengan persyaratan tertentu. Selanjutnya berdasarkan Undang-Undang Nomor 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik Pasal 1 ayat (5), kegiatan yang dilaksanakan oleh creative commons adalah kegiatan penyelenggaran sistem elektronik.Kata Kunci: Creative Commons; Hak Cipta; Lisensi. The development of technology, especially the internet, has made it easier for people to access and distribute information. However, activities such as copy-cut-paste, editing or file sharing may actually harm the copyright law. Based on that, in 2002, a non-profit organization made a breakthrough innovation where it is possible to share and use creativity and knowledge through free legal tools. The research method used in this paper is a normative juridical research method with a focus on the statutory approach and content analysis. Based on the analysis of the discussion, creative commons is not an alternative to copyright law, but rather work side by side and is able to make the creator/copyright holder to modify their rights in the most appropriate circumstances. The use of creative commons licenses in Indonesia is possible according to Article 9 paragraph (1) of Law Number 28 of 2014 concerning Copyright. Furthermore, the rights holder, based on Article 81 of the Copyright Law, able to announce and/or has the right to grant license to other parties based on the license agreement to carry out the action referred to in Article 9 paragraph (1), reproduce their rightful works/products with certain conditions. Furthermore, based on Law Number 11 of 2008 concerning Electronic Information and Transactions Article 1 paragraph (5), the activities carried out by the creative commons are the activities of organizing an electronic system. Keywords: Creative Commons; Copyright; License.
9
Crawford, Rebecca, Katharine S. Gries, Ross Morrison, Satish Valluri, Lynda Doward, and John Fastenau. "The Patient Experience of Relapsed Refractory Multiple Myeloma and Its Treatment: A Social Media Review." Blood 136, Supplement 1 (November 5, 2020): 16. http://dx.doi.org/10.1182/blood-2020-142489.
Full textAbstract:
Background: Patients with relapsed refractory MM (RRMM) report a decline in HRQOL with disease progression and after each relapse, may experience cumulative toxicities from exposure to several lines of therapy. Social media (SM) platforms are rich databases of unfiltered, real-world evidence, where patients share their experiences about diseases and treatments. These platforms provide researchers with a novel approach to understanding the patient perspective. This study aimed to review unsolicited, publicly available patient-reported information (PRI) shared on SM platforms to gain insights into the patient experience of RRMM and its treatment, specifically CAR-T therapy. Methods: Purposeful sampling of PRI were collected from two SM sources (YouTube [video data] and a patient advocacy website Patient Power [patient blogs; https://patientpower.info]) to identify stories of patients living with RRMM. SM posts were included for review if individuals with a self-reported MM diagnosis described their experience with RRMM and provided commentary on CAR-T therapy. Video/blog data were manually reviewed and content analyzed thematically to address experiences of living with MM, and perceptions and experiences of treatment including CAR-T. Demographic information (e.g., sex and age) were extracted from SM posts along with any accompanying disease information, where data were available. Results: Of 43 posts initially identified from the SM sources, 14 were considered relevant to the study objective: 10 videos / 4 blogs connected to 19 unique patients with RRMM (9 male/10 female, patient age range, 51-72 years). One patient reported receiving CAR-T therapy (female, aged 51 years) and was the subject of 5 videos and all 4 blogs. RRMM Impacts: Key symptoms reported included: pain, fatigue, bone fractures, infections, and fever. Patient-reported HRQOL impacts included reduced mobility, impeded ability to work, negative impact on family activities, low mood, anxiety, and a loss of independence. Patients used different strategies (e.g., slower pace of life, planning, and self-advocacy) to adapt to their progressing disease. Treatment Experience: Patients reported switching from one continuous therapy to another in order to achieve remission with varying degrees of success. Positive treatment outcomes were unpredictable; patients who achieved remission were uncertain how durable the remission period would be and expected to relapse. Treatment Decision Drivers: treatment toxicity, impact on daily life, time required for in-hospital treatment, and desire to attain life milestones. Treatment Outcomes: Patients prioritized HRQOL impacts over effectiveness; benefits of treatment-free periods included ability to travel or attending key life events (e.g., family weddings). CAR-T Patient Experience: Patient reported 16 lines of therapy and two stem-cell transplants but never achieved complete remission from these prior treatments. The CAR-T procedure (received in 2018) was described as quick / preferable to previous treatments (e.g., stem cell transplants / continuous chemotherapy) despite a serious cytokine release storm. The patient experienced a rapid improvement, within 1 month of receiving CAR-T, and achieved complete remission which she described as life changing/lifesaving: remission allowed her to return to living a 'normal' life (i.e., working and exercise) and reportedly reduced the burden on family. Conclusions: This study provides valuable insights on the patient perceptions and experience of MM and its treatments using an innovative method for collecting PRI. Although remission was a key treatment outcome for patients, HRQOL and the ability to live their lives on their own terms were often prioritized over treatment effectiveness. The patient who underwent CAR-T therapy experienced a return to a sense of normality as a result of her CAR-T therapy, if for a brief period, which was life changing for both patient and family. Insights generated from this SM review can be used to inform patient-reported outcome measurement strategies for novel treatment clinical development programs. Purposeful sampling of PRI on 2 SM sources limits external validity of insights gathered. The CAR-T experience was a singular experience of one patient; additional insights are to be learned as more patients undergo CAR-T for their RRMM. Disclosures Crawford: RTI Health Solutions: Current Employment. Gries:Janssen: Current Employment, Current equity holder in publicly-traded company. Morrison:RTI Health Solutions: Current Employment. Valluri:Janssen: Current Employment. Doward:RTI Health Solutions: Current Employment. Fastenau:Janssen: Current Employment, Current equity holder in publicly-traded company.
10
Alam, MN, AKMA Kabir, MN Sakib, M. Salahuddin, and MAK Azad. "Impact of livestock rearing practices on public health and environmental issues in selected municipality areas of Bangladesh." Bangladesh Journal of Animal Science 45, no. 1 (April 24, 2016): 44–51. http://dx.doi.org/10.3329/bjas.v45i1.27487.
Full textAbstract:
Livestock keeping at urbanized areas is increasing folds in rate now-a-days in Bangladesh. To characterize the urban livestock keeping practices and its implications on public health and environmental issues in Mymensingh, Gazipur and Shariatpur municipality, Bangladesh, a questionnaire survey was carried out. Ninety livestock keepers were freely characterized and data were obtained through interview. Data were analyzed using percentage and mean. Age does not have any role in keeping livestock at municipal areas. Majority (73%) of the respondents have at least primary education. Male dominates in keeping livestock than female. Local political leader kept the highest number of animals then self-employer or trader takes the second position. Dairy cattle share a lion number (67%) over other species. Ninety five per cent (95%) available breeds in municipal areas are crossbred and the rest is indigenous. More than 75% livestock holders keep their animals over 3 years and only 6% keepers sell their animals within 6 months. Most of the livestock keepers (56%) use their calf as replacement stock. The majority (66%) of the livestock depends on grazing and scavenging for feed from government and municipal lands, unfenced open land, roadsides, rubbish dumps. Most of the livestock owner (66%) does not supplement to their animals with feeds other than free scavenging throughout the rearing time. Most of the farmers (85%) have temporal shed for sheltering their animals during night time. Almost 78% flying herds available in municipal areas drink water from drainage line. Disease outbreaks are 21%, 18%, 17%, 16%, 13%, and 10% of ecto-parasite, mastitis, helminthosis, lumpy skin disease, wounds, and diarrhoea. 14% livestock owner follow vaccination program to keep better their animals from viral or bacterial infections. All the respondents (100%) are aware that livestock keeping could have a negative effect on urban health and environment. More than 50% of the respondents choose dung and urine disposal, malodor and blocked roads are the major damages caused by livestock. Strategies for controlling the damages were as follows: awareness through broadcasting documentary via mass media (4.33), regular health check via veterinary services (3.96), keeping database and regular updated of livestock keepers (3.82), proper disposal of waste (3.69), strengthening rules and policy development for local authority (3.61), reducing numbers of animal (3.48), provision of extension services (3.47), cleaning vicinity daily (3.32). There were some measures taken from public interviewing which need to amend for keeping health and environment free from diseases and pollution.Bang. J. Anim. Sci. 2016. 45 (1): 44-51
Dissertations / Theses on the topic "Sharer (free holder)"
1
Fiawumor, Senyo. "Dynamiques résidentielles dans une ville ouest-africaine : déterminants du statut d'occupation du logement à Lomé (Togo)." Thèse, 2016. http://hdl.handle.net/1866/18421.
Full textAbstract:
La stratégie «Adequate shelter for all and sustainable settlements development in an urbanising world» adoptée au sommet mondial Habitat II d’Istanbul de 1996, traduite dans les Objectifs du Millénaire pour le Développement et maintenant dans les Objectifs de Développement Durable, vise à fournir un logement décent au plus grand nombre de ménages dans les villes du monde et celles d’Afrique Subsaharienne en particulier. La crise du logement caractérisée par les conditions abjectes dans lesquelles la majorité des ménages des villes d’Afrique subsaharienne se logent, devient ainsi un problème majeur auquel la littérature spécialisée promeut généralement, parmi tous les modes d’occupation du logement, l’accession à la propriété comme la panacée. En supposant que cette dimension de la crise du logement ne peut s’expliquer que par les comportements résidentiels des ménages généralement autopromoteurs de leurs logements en Afrique de l’Ouest, et à Lomé la capitale du Togo en particulier, cette thèse de doctorat vise à répondre à la question générale de recherche suivante : Les choix résidentiels à Lomé, en particulier le choix du statut d’occupation du logement, sont-ils exclusivement influencés par le profil des ménages occupants?
Par une approche mixte d’écologie urbaine basée sur des analyses croisées de régression logistique multinomiale appliquées à trois sources de données (RGPH4 de 2010, QUIBB de 2011, TERRAIN 2013) étayées par l’analyse biographique relative aux stratégies résidentielles d’un échantillon de 411 ménages participants dans quatre quartiers de Lomé, choisie comme base empirique, la recherche a plus ou moins confirmé les hypothèses émises a priori par les résultats principaux suivants:
En lien avec la faible mobilité résidentielle générale qui caractérise les pratiques résidentielles à Lomé, les ménages choisissent, en élaborant des stratégies «de petits pas», leur statut d’occupation du logement suivant des trajectoires résidentielles surtout ascendantes, en fonction plus de leur profil démographique (âge, genre, statut migratoire et matrimonial, type et taille) que de leur statut socioéconomique (revenu, emploi, éducation). Ces choix résidentiels sont également déterminés par les attributs des logements (typologie, localisation et accès aux services de base) constituant les parcs résidentiels existants. Les ménages propriétaires de Lomé, souvent biparentaux, sont plus âgés, plus larges que les ménages locataires et hébergés. Les natifs de la ville et les migrants de longue date sont plus enclins à être propriétaires et durablement hébergés que les nouveaux arrivants. Globalement plus fortunés que les hébergés, les propriétaires ne sont pas forcément plus nantis et plus éduqués que les locataires. L’habitat de cour, habitation multifamiliale majoritaire dans le parc résidentiel de Lomé, bien qu’il abrite des ménages de tous les statuts résidentiels, il est surtout réservé aux locataires.
La thèse suggère que des programmes accrus de financement institutionnel du logement, de rénovation générale du parc résidentiel existant et de production d’une version améliorée de l’habitat de cour, avec l’assistance technique publique, contribueront à fournir un logement décent au plus grand nombre de ménages qu’ils soient propriétaires, locataires ou hébergés, à Lomé et ailleurs dans les villes d’Afrique de l’Ouest, conformément au paradigme actuel du développement durable des établissements humains.«Adequate shelter for all and sustainable settlements development in an urbanizing world», strategy adopted in 1996 at the World Summit Habitat II of Istanbul and expressed in the Millennium Development Goals and now in Sustainable Development Goals, aims to provide a decent housing for the greatest number of households in the world and especially in sub-saharian African towns. Since then, access to adequate housing becomes an important issue for housing research in developing and sub-Saharan African countries where most of households still live in abject conditions of lack adequate water and sanitation services which, among others, typify the acute housing crisis they are facing up to. Housing policies and literature generally promote homeownership as the panacea to solve this size of the housing shortage. Assuming that this housing crisis in West Africa, especially in Lomé the capital of Togo, should be explained by the residential behavior of the households, who are self-help promoters in majority, this doctoral thesis try to answer the following general research question: Are the residential choices in Lomé, especially tenure choice, exclusively influenced by the occupier households’ characteristics? By a mixed approach of urban ecology based on multinomial logistic regression cross-study analyses applied to three data sources (RGPH4 2010, QUIBB 2011 and 2013 field survey data) supported by the life histories concerning the residential strategies of a sample of 411 households in four areas of Lomé chosen as empirical basis, the research confirms more or less the assumptions made, by the following main results: In connection with the general low residential mobility that characterizes the residential patterns in Lomé, households make their tenure choices through especially upward trajectories by developing strategies of «small steps», more according to their demographic profile (stage of life cycle, age, gender, migratory and marital status, type, size) than their socioeconomic status (income, employment, education). These residential choices are also determined by the characteristics of the existing residential parks (typology, location, access to basic services of housing). We find that owner-occupiers are often bi-parental households headed by men, older and larger than renter and free-holder households in Lomé. Native and long-term migrant households are more likely to be homeowners and long-term sharers than those who recently migrate. Homeowner households are overall well-off than free-holders, but they are not necessary wealthier and better educated than the renters. The thesis also shows that family house which mainly makes up the residential park of Lomé, is especially kept for renters, although it shelters households of all the tenures. We suggest that steady programmes of housing finance systems extended to all the sectors of the society, concentrated on the access of the current housing stock to basic services and on the supply, with the public technical support, of an improved version of family house, will largely contribute to offer a decent housing to most of the households in Lomé as elsewhere in West African cities, whether they are owner-occupiers, renters or sharers.
Books on the topic "Sharer (free holder)"
1
Back, Kerry E. Equilibrium and Efficiency. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780190241148.003.0004.
Full textAbstract:
Pareto optima and competitive equilibria are defined. Allocations are functions of market wealth (sharing rules) in Pareto optima, which means that all risks except market wealth are perfectly shared. Equilibria in complete markets are shown to be equivalent to Arrow‐Debreu equilibria and to be Pareto optimal. If investors all have linear risk tolerance with the same cautiousness parameter, then equilibria are Pareto optimal, equilibrium prices are independent of the initial wealth allocation (Gorman aggregation), and two‐fund separation holds (all investors hold the risk‐free asset and the market portfolio).
2
Bringhurst, Piper L., and Gerald Gaus. Positive Freedom and the General Will. Edited by David Schmidtz and Carmen E. Pavel. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199989423.013.1.
Full textAbstract:
This chapter shows how one understanding of positive liberty—freedom as reasoned control—is presupposed by relations of moral responsibility. Rousseau’s “quixotic quest”—insuring that all subjects of the moral law remain morally free—is necessary to maintain responsibility relations within a moral community. Unless all are free to exercise reasoned control in accepting moral demands, they cannot be held responsible for failure to comply. We then inquire whether the concept of the general will can reconcile positive freedom and moral responsibility with regulation by a common moral law. Rousseau’s account seems inappropriate for a deeply diverse society because it holds that the general will arises from an essential identity of citizens’ interests. Instead, Bosanquet’s work suggests two contemporary proposals for ways in which a diverse society might share a general will, explaining in turn how its members are all fit to be held responsible for violating its moral rules.
3
Brown, Kate Pride. Baikal Goes Global. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190660949.003.0003.
Full textAbstract:
This chapter traces the relational position of civil society through the history of three key organizations: Baikal Environmental Wave, the Tahoe-Baikal Institute, and the Great Baikal Trail. The development of local environmental civil society around Lake Baikal in the post-Soviet years was conditioned by two important changes. First, the Soviet collapse opened the door to global interaction. Local civil society was inextricably linked to global networks and forces that shaped the course of its development. Second, civil society’s strength and independence shifted along with the status of other power holders in the larger field. In the 1990s, the economy and the state were in crisis and collapse. Civil society was then most free to define itself and take aggressive positions. As the two opposing powers recover in the 2000s, accommodation to economic and political power is preferred.
4
Janaway, Christopher. Affect and Cognition in Schopenhauer and Nietzsche. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198766858.003.0011.
Full textAbstract:
Schopenhauer holds that emotions impair cognition, while Nietzsche apparently replies that they are ineliminable from cognition, and that they enhance it. For Schopenhauer, human cognition is normally in the service of affective states that he classes as ‘movements of the will’. But he sees cognition as spoiled, warped, or tainted by its inability to shake off the emotions, desires, or drives that belong to human nature. The exception is a rare kind of cognition in which an individual becomes the ‘pure subject of cognition’. Nietzsche accepts something analogous to Schopenhauer’s descriptive position on the relation between cognition and the affects. But he firmly rejects Schopenhauer’s evaluative stance, and denies the possibility of a pure, objective, affect-free cognition. Nietzsche argues that the influence of the affects on human cognition is not only necessary, but beneficial. This, the chapter argues, is at the heart of Nietzsche’s famous ‘perspectivism’.
5
Gonaver, Wendy. The Peculiar Institution and the Making of Modern Psychiatry, 1840-1880. University of North Carolina Press, 2019. http://dx.doi.org/10.5149/northcarolina/9781469648446.001.0001.
Full textAbstract:
Though the origins of asylums can be traced to Europe, the systematic segregation of the mentally ill into specialized institutions occurred in the United States only after 1800, just as the struggle to end slavery took hold. This book examines the relationship between these two historical developments, showing how slavery and ideas about race shaped early mental health treatment in the United States, especially in the South. These connections are illuminated through the histories of two asylums in Virginia: the Eastern Lunatic Asylum in Williamsburg, the first in the nation; and the Central Lunatic Asylum in Petersburg, the first created specifically for African Americans. Eastern Lunatic Asylum was the only institution to accept both slaves and free blacks as patients and to employ slaves as attendants. Drawing from these institutions' untapped archives, this book reveals how slavery influenced ideas about patients’ rights, about the proper relationship between caregiver and patient, about what constituted healthy religious belief and unhealthy fanaticism, and about gender. This early form of psychiatric care acted as a precursor to public health policy for generations.
6
Noyalas, Jonathan A. Slavery and Freedom in the Shenandoah Valley during the Civil War Era. University Press of Florida, 2021. http://dx.doi.org/10.5744/florida/9780813066868.001.0001.
Full textAbstract:
In Slavery and Freedom in the Shenandoah Valley during the Civil War Era, Jonathan Noyalas examines the complexities of life for African Americans in Virginia’s Shenandoah Valley from the antebellum period through Reconstruction. Although the Valley was a site of fierce conflicts during the Civil War and its military activity has been extensively studied, scholars have largely ignored the black experience in the region until now. Correcting previous assumptions that slavery was not important to the Valley, and that enslaved people were treated better there than in other parts of the South, Jonathan Noyalas demonstrates the strong hold of slavery in the region. He explains that during the war, enslaved and free African Americans navigated a borderland that changed hands frequently—where it was possible to be in Union territory one day, Confederate territory the next, and no-man’s land another. He shows that the region’s enslaved population resisted slavery and supported the Union war effort by serving as scouts, spies, and laborers, or by fleeing to enlist in regiments of the United States Colored Troops. Noyalas draws on untapped primary resources, including thousands of records from the Freedmen’s Bureau and contemporary newspapers, to continue the story and reveal the challenges African Americans faced from former Confederates after the war. He traces their actions, which were shaped uniquely by the volatility of the struggle in this region, to ensure that the war’s emancipationist legacy would survive.
7
Hardin, Garrett. Living within Limits. Oxford University Press, 1993. http://dx.doi.org/10.1093/oso/9780195078114.001.0001.
Full textAbstract:
We fail to mandate economic sanity, writes Garrett Hardin, "because our brains are addled by...compassion." With such startling assertions, Hardin has cut a swathe through the field of ecology for decades, winning a reputation as a fearless and original thinker. A prominent biologist, ecological philosopher, and keen student of human population control, Hardin now offers the finest summation of his work to date, with an eloquent argument for accepting the limits of the earth's resources--and the hard choices we must make to live within them. In Living Within Limits, Hardin focuses on the neglected problem of overpopulation, making a forceful case for dramatically changing the way we live in and manage our world. Our world itself, he writes, is in the dilemma of the lifeboat: it can only hold a certain number of people before it sinks--not everyone can be saved. The old idea of progress and limitless growth misses the point that the earth (and each part of it) has a limited carrying capacity; sentimentality should not cloud our ability to take necessary steps to limit population. But Hardin refutes the notion that goodwill and voluntary restraints will be enough. Instead, nations where population is growing must suffer the consequences alone. Too often, he writes, we operate on the faulty principle of shared costs matched with private profits. In Hardin's famous essay, "The Tragedy of the Commons," he showed how a village common pasture suffers from overgrazing because each villager puts as many cattle on it as possible--since the costs of grazing are shared by everyone, but the profits go to the individual. The metaphor applies to global ecology, he argues, making a powerful case for closed borders and an end to immigration from poor nations to rich ones. "The production of human beings is the result of very localized human actions; corrective action must be local....Globalizing the 'population problem' would only ensure that it would never be solved." Hardin does not shrink from the startling implications of his argument, as he criticizes the shipment of food to overpopulated regions and asserts that coercion in population control is inevitable. But he also proposes a free flow of information across boundaries, to allow each state to help itself. "The time-honored practice of pollute and move on is no longer acceptable," Hardin tells us. We now fill the globe, and we have no where else to go. In this powerful book, one of our leading ecological philosophers points out the hard choices we must make--and the solutions we have been afraid to consider.
Book chapters on the topic "Sharer (free holder)"
1
Singh, Pushpa, and Narendra Singh. "Analysis of Free and Open Source Software (FOSS) Product in Web Based Client-Server Architecture." In Research Anthology on Usage and Development of Open Source Software, 96–108. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-9158-1.ch005.
Full textAbstract:
Free and open source software (FOSS) differs from proprietary software. FOSS facilitates the design of various applications per the user's requirement. Web applications are not exceptional in this way. Web-based applications are mostly based on client server architecture. This article is an analytical study of FOSS products used in web-based client server architecture. This article will provide information about FOSS product such as FireFox (web browser), Apache (web server) and MySQL (RDBMS). These reveal that various FOSS products such as Apache server covers 65% of the market share, while MySQL covers 58.7% market share and hold the top-most rank.
2
Dailey, Anne C. "The Psychoanalytic Tradition in American Law." In Law and the Unconscious. Yale University Press, 2017. http://dx.doi.org/10.12987/yale/9780300188837.003.0003.
Full textAbstract:
This chapter surveys the long and important tradition of law and psychoanalysis in the United States beginning with the work of Oliver Wendell Holmes, Jr., up to the mid-twentieth century. While “tradition” may seem too strong a term for the diverse collection of psychoanalytic writings carried out by legal thinkers over the course of more than a half-century, what ties this work together is a shared recognition of the unconscious depths of the human psyche and the common questions that a psychoanalytic perspective on human behavior raises for law. As this chapter details, many early- to midcentury legal thinkers and judges turned to psychoanalytic ideas for help in addressing a broad set of concerns, including the value of free speech in a democracy, the processes of judicial decision-making, degrees of criminal responsibility, and child custody. The chapter focuses on those legal thinkers in this period whose attention was captured by the unconventional, sometimes even shocking, psychoanalytic ideas about the unconscious, guilt, free will, conflict, instinctual drives, sexuality, and early childhood experience. A study of the psychoanalytic tradition in American law is essential for understanding the vital contribution that contemporary psychoanalysis can make to law today.
3
Howe, Paul. "Adolescent Society, Then and Now." In Teen Spirit, 1–11. Cornell University Press, 2020. http://dx.doi.org/10.7591/cornell/9781501749827.003.0001.
Full textAbstract:
This introductory chapter discusses how nowadays, individuals aged twenty to eighty seem little concerned about adhering to traditional adult norms, favoring instead the free and easy ways of youth. In some cases, this may reflect a deliberate effort to adopt a youthful frame of mind in an attempt to stave off the inescapable reality of growing older. But often an adolescent way of thinking and acting seems to come very naturally to people. Instead of consciously seeking to recapture their youth, they are simply doing and expressing what feels instinctively right, reflecting the fact that in some important sense they have never really fully grown up. Examples of adults acting like adolescents support the conclusion that a youthful spirit now holds considerable sway and has reshaped important elements of modern adulthood. One way to gain insight into these changes is to look closely at teenagers themselves and their shared social setting.
4
Gooding Jr., Frederick W. "“Can I Get in on the Joke, Too?”." In Analyzing Language and Humor in Online Communication, 164–76. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-5225-0338-5.ch009.
Full textAbstract:
This chapter explores the ramifications of having race-based “dirty laundry” aired through humor, without necessarily being dirty jokes. Not only is the United States of America reputed to be a “free country,” but also there are few restrictions on Internet participation outside of obvious legal infractions. Thus, while repulsive in their worst form or in poor taste in their naive form, racist jokes are not regulated on the Internet. Nor is expressing or espousing racism online in and of itself illegal. Currently our legal system is designed to respond or react to manifestations of racist thought when acted out against another in the physical realm (e.g., denying another a job based upon their race or inflicting bodily harm when motivated by racial animus). While we presume that most would not want to entertain destructive thoughts, people are free to hold, share and emote racist ideas in cyberspace. Thus, with the ever-expanding role of the Internet in many of our lives, it is important to interrogate whether such publicly broadcast in-group humor will desensitize other members of other races outside of the joke. This chapter will tease out the implications of the continued sharing online of racial humor, with those both in and outside of the original joke.
5
Wilson, James Lindley. "Equality as a Social Ideal." In Democratic Equality, 17–47. Princeton University Press, 2019. http://dx.doi.org/10.23943/princeton/9780691190914.003.0002.
Full textAbstract:
This chapter discusses how the ideal of equal status connects to democratic aspirations, and why people should take that ideal seriously. Equality of status constitutes, and is constituted by, relations of an egalitarian kind. When people mutually recognize one another's equal status, they put themselves in an egalitarian relation. However, there are further connections between status equality and egalitarian relations, in that the recognition of equal status in various respects helps promote relationships among citizens free of hierarchy, domination, servility, and the like. These further connections are contingent, depending upon truths of empirical sociology and psychology—about how, in fact, humans tend to respond to certain social conditions, like material or political inequality. A similar structure holds for the ideal of political equality. The shared status of “democratic citizen” is constituted by a range of expectations that regulate institutions and individual practices. That status is properly recognized when institutions and practices meet those expectations. When citizens mutually recognize one another's status, they thereby engage in, and promote, valuable egalitarian political relations.
6
Aizawa, Tatsuhiko, Tadahiko Inonara, Tomoaki Yoshino, Tomomi Shiratori, and Yohei Suzuki. "Laser Treatment CVD Diamond Coated Punch for Ultra-Fine Piercing of Metallic Sheets." In Engineering Applications of Diamond. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96446.
Full textAbstract:
CVD-diamond coated special tools have been widely utilized to prolong their tool life in practical production lines. WC (Co) punch for fine piercing of metallic sheets required for high wear-toughness to be free from chipping and damages and for high product quality to punch out the holes with sufficient dimensional accuracy. The laser trimming process was developed to reduce the surface roughness of diamond coating down to submicron level and to adjust its diamond layer dimensions with a sharp punch edge for accurate piercing. The pulsed laser irradiation was employed to demonstrate that micro-groove was accurately formed into the diamond coating. Less deterioration in the worked diamond film by this laser treatment was proved by the Raman spectroscopy. The femtosecond laser trimming was proposed to sharpen the punch edge down to 2 μm and to form the nano-textured punch side surfaces with the LIPSS (Laser Induced Periodic Surface Structuring)-period of 300 nm. Fine piercing experiments were performed to demonstrate that punch life was significantly extended to continuous punching in more than 10,000 shots and that mirror-shining hole surfaces were attained in every shot by regularly coining the nanotextures. The sharp punch edge with homogeneous edge profile was responsible for reduction of the induced damages into work sheet by piercing. The punch life was extended by the ejection mechanism of debris particles through the nanotextures on the punch side surface. The present laser treatment was useful in trimming and nanostructuring the complex-shaped punch edge for industrial application.
7
Shahpari, Hasan, and Tahereh Alavi Hojjat. "Religious Economies and Religious Mobility." In Research Anthology on Religious Impacts on Society, 58–94. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-3435-9.ch004.
Full textAbstract:
Religious economies are a novel idea with potential application in a free market economy. They bring the idea of the existence of the supernatural and concern with ultimate meanings, so ubiquitous to religions, in touch with the multiplicity of paths available to us. In Islamic Sufism, there are as many paths to God as there are individuals. A situation in which people could compare and evaluate religions, regarding them as a matter of choice, can best described as a religious economy. Just as commercial economies consist of a market in which different firms compete, religious economies consist of a market (the aggregate demand for religion) and firms (different religious organizations) seeking to attract and hold clienteles. Just as commercial economies must deal with state regulations, religious economies' key issue is the degree to which they are regulated by the state. From Stark's viewpoint, the natural state of a religious economy is religious pluralism, wherein many religious “firms” exist because of their special appeal to certain segments of the market or the population. However, just as there is incentive for a commercial organization to monopolize the market to maximize its profit, it is always in the interest of any particular religious organization to secure a monopoly, maintain its followers, and expand into new interest groups. This can be achieved, (and even then to a very limited extent) only if the state forcibly excludes competing faiths (Stark, 2001). The building blocks of Stark's ideas are the assumption of a free market, a market economy, and the key issue of rational choice theory, hand in hand with American Pragmatism. As with the history of religions, which are not and have not been free from contest and cooperation, similarities, and differences, so religious economies have not been and are not easily shaped without considering forces from within and among different economies. Religious actions, reactions, and interactions in monotheism, diversity of textual interpretations, the growth of intellectualism or counter-intellectualism, human perception of transcendence and the sacred, as well as the realities of everyday life, all imply that the idea of religious economies needs more exploration. Christianity and Islam, one dominating the West and the other the East and Africa, offer the instances of two massive markets. Each religion has more than a billion adherents and a history of sharing the monotheistic market. Both religions, in spite of Islamophobia in the West, have formed and will participate in the decline, incline, or stability of the market. This subject is timely in light of the political movements in the Middle East and monolithic misconception of Islam.
8
"Religious Economies and Religious Mobility." In Islamic Economy and Social Mobility, 292–327. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-4666-9731-7.ch012.
Full textAbstract:
Religious economies are a novel idea with potential application in a free market economy. They bring the idea of the existence of the supernatural and concern with ultimate meanings, so ubiquitous to religions, in touch with the multiplicity of paths available to us. In Islamic Sufism, there are as many paths to God as there are individuals. A situation in which people could compare and evaluate religions, regarding them as a matter of choice, can best described as a religious economy. Just as commercial economies consist of a market in which different firms compete, religious economies consist of a market (the aggregate demand for religion) and firms (different religious organizations) seeking to attract and hold clienteles. Just as commercial economies must deal with state regulations, religious economies' key issue is the degree to which they are regulated by the state. From Stark's viewpoint, the natural state of a religious economy is religious pluralism, wherein many religious “firms” exist because of their special appeal to certain segments of the market or the population. However, just as there is incentive for a commercial organization to monopolize the market to maximize its profit, it is always in the interest of any particular religious organization to secure a monopoly, maintain its followers, and expand into new interest groups. This can be achieved, (and even then to a very limited extent) only if the state forcibly excludes competing faiths (Stark, 2001). The building blocks of Stark's ideas are the assumption of a free market, a market economy, and the key issue of rational choice theory, hand in hand with American Pragmatism. As with the history of religions, which are not and have not been free from contest and cooperation, similarities, and differences, so religious economies have not been and are not easily shaped without considering forces from within and among different economies. Religious actions, reactions, and interactions in monotheism, diversity of textual interpretations, the growth of intellectualism or counter-intellectualism, human perception of transcendence and the sacred, as well as the realities of everyday life, all imply that the idea of religious economies needs more exploration. Christianity and Islam, one dominating the West and the other the East and Africa, offer the instances of two massive markets. Each religion has more than a billion adherents and a history of sharing the monotheistic market. Both religions, in spite of Islamophobia in the West, have formed and will participate in the decline, incline, or stability of the market. This subject is timely in light of the political movements in the Middle East and monolithic misconception of Islam.
9
Meyer, William B. "Since 1945: New Amenities, New Hazards." In Americans and Their Weather. Oxford University Press, 2000. http://dx.doi.org/10.1093/oso/9780195131826.003.0011.
Full textAbstract:
If the average citizen's surroundings defined the national climate, then the United States grew markedly warmer and drier in the postwar decades. Migration continued to carry the center of population west and began pulling it southward as well. The growth of what came to be called the Sunbelt at the "Snowbelt's" expense passed a landmark in the early 1960s when California replaced New York as the most populous state. Another landmark was established in the early 1990s when Texas moved ahead of New York. In popular discussion, it was taken for granted that finding a change of climate was one of the motives for relocating as well as one of the results. It was not until 1954, though, that an American social scientist first seriously considered the possibility. The twentieth-century flow of Americans to the West Coast, the geographer Edward L. Ullman observed in that year, had no precedent in world history. It could not be explained by the theories of settlement that had worked well in the past, for a substantial share of it represented something entirely new, "the first large-scale in-migration to be drawn by the lure of a pleasant climate." If it was the first of its kind, it was unlikely to be the last. For a set of changes in American society, Ullman suggested, had transformed the economic role of climate. The key changes included a growth in the numbers of pensioned retirees; an increase in trade and service employment, much more "footloose" than agriculture or manufacturing was; developments in technology making manufacturing itself more footloose; and a great increase in mobility brought about by the automobile and the highway. All in one way or another had weakened the bonds of place and made Americans far freer than before to choose where to live. Whatever qualities made life in any spot particularly pleasant thus attracted migration more than in the past. Ullman grouped such qualities together as "amenities." They ranged from mountains to beaches to cultural attractions, but climate appeared to be the most important, not least because it was key to the enjoyment of many of the rest. Ullman did not suppose that all Americans desired the same climate. For most people, in this as in other respects, "where one was born and lives is the best place in the world, no matter how forsaken a hole it may appear to an outsider."
Conference papers on the topic "Sharer (free holder)"
1
Saumweber, Christian, Achmed Schulz, and Sigmar Wittig. "Free-Stream Turbulence Effects on Film Cooling With Shaped Holes." In ASME Turbo Expo 2002: Power for Land, Sea, and Air. ASMEDC, 2002. http://dx.doi.org/10.1115/gt2002-30170.
Full textAbstract:
A comprehensive set of generic experiments has been conducted to investigate the effect of elevated free-stream turbulence on film cooling performance of shaped holes. A row of three cylindrical holes as a reference case, and two rows of holes with expanded exits, a fanshaped (expanded in lateral direction), and a laidback fanshaped hole (expanded in lateral and streamwise direction) have been employed. With an external (hot gas) Mach number of Mam = 0.3 operating conditions are varied in terms of free-stream turbulence intensity (up to 11%), integral length scale at constant turbulence intensity (up to 3.5 hole inlet diameters), and blowing ratio. The temperature ratio is fixed at 0.59 leading to an engine-like density ratio of 1.7. The results indicate that shaped and cylindrical holes exhibit very different reactions to elevated free-stream turbulence levels. For cylindrical holes film cooling effectiveness is reduced with increased turbulence level at low blowing ratios whereas a small gain in effectiveness can be observed at high blowing ratios. For shaped holes, increased turbulence intensity is detrimental even for the largest blowing ratio (M = 2.5). In comparison to the impact of turbulence intensity the effect of varying the integral length scale is found to be of minor importance. Finally the effect of elevated free-stream turbulence in terms of heat transfer coefficients was found to be much more pronounced for the shaped holes.
2
Saumweber, Christian, and Achmed Schulz. "Free-Stream Effects on the Cooling Performance of Cylindrical and Fan-Shaped Cooling Holes." In ASME Turbo Expo 2008: Power for Land, Sea, and Air. ASMEDC, 2008. http://dx.doi.org/10.1115/gt2008-51030.
Full textAbstract:
From literature and our own studies it is known that the effects of hot gas cross-flow and in particular the turbulence of the hot gas flow highly influence the spreading of the coolant in the near hole vicinity. Moreover, the velocity of the hot gas flow expressed by a hot gas Mach number obviously plays a much more important role in case of diffuser holes than with simple cylindrical holes. To realize a certain blowing rate, a higher pressure ratio needs to be established in case of higher Mach numbers. This in turn may strongly affect the diffusion process in the expanded portion of a fan-shaped cooling hole. The said effects will be discussed in great detail. The effects of free-stream Mach number and free-stream turbulence, including turbulence intensity, integral length scale, and periodic unsteady wake flow will be considered. The comparative study is performed by means of discharge coefficients and by local and laterally averaged adiabatic film cooling effectiveness and heat transfer coefficients. Both cooling holes have a length-to-diameter ratio of 6 and an inclination angle of 30°. The fan-shaped hole has an expansion angle of 14°. The effect of the coolant cross-flow at the hole entrance is not considered in this study, i.e. plenum conditions exist at the hole entrance.
3
Chen, Andrew F., Shiou-Jiuan Li, and Je-Chin Han. "Film Cooling With Forward and Backward Injection for Cylindrical and Fan-Shaped Holes Using PSP Measurement Technique." In ASME Turbo Expo 2014: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/gt2014-26232.
Full textAbstract:
A systematic study was performed to investigate the combined effects of hole geometry, blowing ratio, density ratio and free-stream turbulence intensity on flat plate film cooling with forward and backward injection. Detailed film cooling effectiveness distributions were obtained using the steady state pressure sensitive paint (PSP) technique. Four common film-hole geometries with forward injection were used in this study: simple angled cylindrical holes and fan-shaped holes, and compound angled (β = 45°) cylindrical holes and fan-shaped holes. Additional four film-hole geometries with backward injection were tested by reversing the injection direction from forward to backward to the mainstream. There are seven holes in a row on each plate and each hole is 4 mm in diameter. The hole length to diameter ratio is 7.5. The blowing ratio effect was studied at 10 different blowing ratios ranging from M = 0.3 to M = 2.0. The coolant to main stream density ratio (DR) effect was studied by using foreign gases with DR = 1 (N2), 1.5 (CO2), and 2 (15% SF6 + 85% Ar). The free stream turbulence intensity effect was tested at 0.5% and 6%. The results show higher density coolant provides higher effectiveness than lower density coolant, fan-shaped holes perform better than cylindrical holes, and compound angled holes are better than simple angled holes. In general, the results show the film cooling effectiveness with backward injection is greatly reduced for shaped holes as compared with the forward injection. However, significant improvements can be seen in both simple angled and compound angled cylindrical holes at higher blowing ratios and density ratio (DR = 2). Comparison was made between experimental data and empirical correlations for simple angled fan-shaped holes at engine representative density ratios. An improved correlation which covers a wider range of density ratios (DR = 1.0 to DR = 2.0) is proposed.
4
Lu, Yiping, David Faucheaux, and Srinath V. Ekkad. "Film Cooling Measurements for Novel Hole Configurations." In ASME 2005 Summer Heat Transfer Conference collocated with the ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems. ASMEDC, 2005. http://dx.doi.org/10.1115/ht2005-72396.
Full textAbstract:
Film cooling performance for a row of cylindrical holes can be. The effect of the slot exit area and shape is investigated. Detailed heat transfer coefficient and film effectiveness measurements are obtained simultaneously using a single test transient IR thermography technique. The study is performed at a single mainstream Reynolds number based on free-stream velocity and film hole diameter of 7150 at three different coolant-to-mainstream blowing ratios of 0.5, 1.0, and 1.5. Two designs with a crescent shaped exit and a slot exit are considered. The results show that the crescent shaped exits provide significantly higher film cooling effectiveness than the cylindrical hole exit at all blowing ratios. The converging slot exit provides similar effectiveness as the crescent for higher blowing ratios. However, the crescent shape also enhances heat transfer coefficients significantly. Overall effectiveness for both crescent and converging slot exits are clearly superior to the standard cylindrical hole.
5
Fu, Qiang, and Zezhong C. Chen. "Medial Axis Transform of Planar Shapes With Free-Form Curve Boundary." In ASME 2010 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/detc2010-28903.
Full textAbstract:
Medial axis transform (MAT) is a very useful shape interrogation tool in NC tool path generation for pocket milling. This paper presents a new, efficient approach to calculating MATs of planar profiles with boundaries of free-form curves. The proposed approach is mainly based on profile boundary tracing and decomposition. By studying the basic elements of MAT and their geometric properties, several algorithms of finding contact circles are developed. The boundary tracing algorithm can handle profiles with/without internal holes. For a profile without internal holes, it is continuously divided into simpler sub-profiles while travelling along the boundary, and a tree data structure is adopted to keep track of the boundary decomposition process. For a profile with internal holes, it is divided into several simple profiles without internal holes. After generating the MAT of each simple profile, the completed MAT can be found by combining these MATs. This proposed approach is implemented and some illustrative samples are presented to demonstrate its advantages.
6
Mhetras, Shantanu, Je-Chin Han, and Ron Rudolph. "Film-Cooling Effectiveness From Shaped Film Cooling Holes for a Gas Turbine Blade." In ASME Turbo Expo 2008: Power for Land, Sea, and Air. ASMEDC, 2008. http://dx.doi.org/10.1115/gt2008-50916.
Full textAbstract:
The effect of film cooling holes placed along the span of a fully-cooled high pressure turbine blade in a stationary, linear cascade on film cooling effectiveness is studied using the Pressure Sensitive Paint (PSP) technique. Six rows of compound angled shaped film cooling holes are provided on the pressure side while four such rows are provided on the suction side of the blade. The holes have a laidback and fan-shaped diffusing cross-section. Another three rows of holes are drilled on the leading edge to capture the effect of showerhead film coolant injection. The film cooling hole arrangement simulates a typical film cooled blade design used in stage 1 rotor blades for gas turbines used for power generation. A minimum blowing ratio is defined for each film hole row and tests are performed for 1.0x, 1.33x, 1.67x, 2.0x and 2.67x of this minimum value. Tests are performed for an inlet Mach number of 0.36 with a corresponding exit Mach number of 0.51. The flow remains subsonic in the throat region. The corresponding free stream Reynolds number, based on the axial chord length and the exit velocity, is 1.3 million. Turbulence intensity level at the cascade inlet is 5% with an integral length scale of around 5cm. Results show that varying blowing ratios can have a significant impact on film-cooling effectiveness distribution. Large spanwise variations in effectiveness distributions are also observed. Results also show that the effectiveness magnitudes from superposition of effectiveness data from individual rows are comparable with that from full coverage film cooling.
7
Lu, Yiping, Alok Dhungel, Srinath V. Ekkad, and Ronald S. Bunker. "Film Cooling Measurements for Cratered Cylindrical Inclined Holes." In ASME Turbo Expo 2007: Power for Land, Sea, and Air. ASMEDC, 2007. http://dx.doi.org/10.1115/gt2007-27386.
Full textAbstract:
Film cooling performance is studied for cylindrical holes embedded in craters. Different crater geometries are considered for a typical crater depth. Cratered holes may occur when blades are coated with thermal barrier coating layers by masking the hole area during TBC spraying resulting in hole surrounded by TBC layer. The film performance and behavior is expected to be different for the cratered holes compared to standard cylindrical holes. Detailed heat transfer coefficient and film effectiveness measurements are obtained simultaneously using a single test transient IR thermography technique. The study is performed at a single mainstream Reynolds number based on free-stream velocity and film hole diameter of 11000 at four different coolant-to-mainstream blowing ratios of 0.5, 1.0, 1.5 and 2.0. The results show that film cooling effectiveness is slightly enhanced by cratering of holes but a substantial increase in heat transfer enhancement negates the benefits of higher film effectiveness. Three different crater geometries are studied and compared to a baseline flush cylindrical hole, a trenched hole, and a typical diffuser shaped hole. CFD simulation using Fluent was also performed to determine the jet-mainstream interactions associated with the experimental surface measurements.
8
Liu, Kevin, Shang-Feng Yang, and Je-Chin Han. "Influence of Coolant Density on Turbine Platform Film-Cooling With Stator-Rotor Purge Flow and Compound-Angle Holes." In ASME Turbo Expo 2013: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/gt2013-94155.
Full textAbstract:
A detailed parametric study of film-cooling effectiveness was carried out on a turbine blade platform. The platform was cooled by purge flow from a simulated stator-rotor seal combined with discrete hole film-cooling. The cylindrical holes and laidback fan-shaped holes were accessed in terms of film-cooling effectiveness. This paper focuses on the effect of coolant-to-mainstream density ratio on platform film-cooling (DR = 1 to 2). Other fundamental parameters were also examined in this study — a fixed purge flow of 0.5%, three discrete-hole film-cooling blowing ratios between 1.0 and 2.0, and two freestream turbulence intensities of 4.2% and 10.5%. Experiments were done in a five-blade linear cascade with inlet and exit Mach number of 0.27 and 0.44, respectively. Reynolds number of the mainstream flow was 750,000 and wad based on the exit velocity and chord length of the blade. The measurement technique adopted was conduction-free pressure sensitive paint (PSP) technique. Results indicated that with the same density ratio, shaped holes present higher film-cooling effectiveness and wider film coverage than the cylindrical holes, particularly at higher blowing ratios. The optimum blowing ratio of 1.5 exists for the cylindrical holes, whereas the effectiveness for the shaped holes increases with increase of blowing ratio. Results also show that the platform film-cooling effectiveness increases with density ratio but decreases with turbulence intensity.
9
Reiss, H., and A. Bölcs. "Experimental Study of Showerhead Cooling on a Cylinder Comparing Several Configurations Using Cylindrical and Shaped Holes." In ASME 1999 International Gas Turbine and Aeroengine Congress and Exhibition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/99-gt-123.
Full textAbstract:
Film cooling and heat transfer measurements on a cylinder model have been conducted using the transient thermochromic liquid crystal technique. Three showerhead cooling configurations adapted to leading edge film cooling of gas turbine blades were directly compared: ‘classical’ cylindrical holes versus two types of shaped hole exits. The experiments were carried out in a free jet test facility at two different flow conditions, Mach numbers M = 0.14 and M = 0.26, yielding Reynolds numbers based on the cylinder diameter of 8.6e4 and 1.55e5, respectively. All experiments were done at a main stream turbulence level of Tu = 7% with an integral lengthscale of Lx = 9.1mm (M = 0.14), or Lx = 10.5mm (M = 0.26) respectively. Foreign gas injection (CO2) was used yielding an engine-near density ratio of 1.6, with blowing ratios ranging from 0.6 to 1.5. Detailed experimental results are shown, including surface distribution of film cooling effectiveness and local heat transfer coefficients. Additionally, heat transfer and heat load augmentation due to injection with respect to the uncooled cylinder are reported. For a given cooling gas consumption the laid-back shaped hole exits lead to a clear enhancement of the cooling performance compared to cylindrical exits, whereas laterally expanded holes give only slight performance enhancement.
10
Kingery, J. E., and F. E. Ames. "Full Coverage Shaped Hole Film Cooling in an Accelerating Boundary Layer With High Free-Stream Turbulence." In ASME Turbo Expo 2015: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/gt2015-42233.
Full textAbstract:
Full coverage shaped-hole film cooling and downstream heat transfer measurements have been acquired in the accelerating flows over a large cylindrical leading edge test surface. The shaped holes had an 8° lateral expansion angled at 30° to the surface with spanwise and streamwise spacings of 3 diameters. Measurements were conducted at four blowing ratios, two Reynolds numbers and six well documented turbulence conditions. Film cooling measurements were acquired over a four to one range in blowing ratio at the lower Reynolds number and at the two lower blowing ratios for the higher Reynolds number. The film cooling measurements were acquired at a coolant to free-stream density ratio of approximately 1.04. The flows were subjected to a low turbulence condition (Tu = 0.7%), two levels of turbulence for a smaller sized grid (Tu = 3.5%, and 7.9%), one turbulence level for a larger grid (8.1%), and two levels of turbulence generated using a mock aero-combustor (Tu = 9.3% and 13.7%). Turbulence level is shown to have a significant influence in mixing away film cooling coverage progressively as the flow develops in the streamwise direction. Effectiveness levels for the aero-combustor turbulence condition are reduced to as low as 20% of low turbulence values by the furthest downstream region. The film cooling discharge is located close to the leading edge with very thin and accelerating upstream boundary layers. Film cooling data at the lower Reynolds number, show that transitional flows have significantly improved effectiveness levels compared with turbulent flows. Downstream effectiveness levels are very similar to slot film cooling data taken at the same coolant flow rates over the same cylindrical test surface. However, slots perform significantly better in the near discharge region. These data are expected to be very useful in grounding computational predictions of full coverage shaped hole film cooling with elevated turbulence levels and acceleration. IR measurements were performed for the two lowest turbulence levels to document the spanwise variation in film cooling effectiveness and heat transfer.