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Journal articles on the topic 'Sharp violation of cerebral circulation of blood'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Inna, Pulyaeva, Prasol Vitaliy, Miasoiedov Kyrylo, and Ivanova Yuliya. "Cardiovascular complications in patients with acute ischemia of the limbs in the early period of ischemic stroke." ScienceRise: Medical Science, no. 2(35) (March 31, 2020): 15–18. https://doi.org/10.15587/2519-4798.2020.199859.

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<strong>Aim.</strong><strong> </strong>To define risks and complications for patients with the sharp ischemia of lower extremities in the sharp period of stroke after reconstructive surgical treatment for the decline of amount of amputations and sharp violations of cerebral circulation of blood postoperative period. <strong>Materials and methods.</strong> In the period 2015–2019 based on the Department of Acute Diseases of Vessels of the State Institution «ICUS by. VT Zaitsev NAMNU »we operated 31 patients for acute ischemia of the lower extremities during the perio

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2

Kotsyumbas, G. I., and M. R. Khalaniia. "Pathomorphology of the cerebral cortex of cats for infectious peritonitis." Scientific Messenger of LNU of Veterinary Medicine and Biotechnology 21, no. 93 (2019): 3–9. http://dx.doi.org/10.32718/nvlvet9301.

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The article presents the results of histological studies of the frontal area of the cerebral cortexб taken from 10 corpses of cats aged from 3 months to 5.5 years, in which infectious peritonitis (based on anamnesis, clinical signs, morphological and biochemical blood analysis , ultrasound diagnostics, Rivalt test and express diagnosis) was diagnosed during their life. A pathoanatomical study was conducted; samples of the frontal area of the cerebral cortex of cats, which were fixed in a 12% aqueous solution of neutral formalin, a solution of Carnoua and 96° ethyl alcohol, were selected. The h

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3

Slobodyan, Zh H., and I. V. Savуtskyi. "LIPID PEROXIDATION AND ANTIOXIDANT PROTECTION SYSTEM IN RATS UNDER CONDITIONS OF ISCHEMIC STROKE ON THE BACKGROUND OF ANXIETY-DEPRESSIVE DISORDERS." Medical Science of Ukraine (MSU) 19, no. 2 (2023): 66–71. http://dx.doi.org/10.32345/2664-4738.2.2023.09.

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Background. Acute disorders of cerebral blood circulation are one of the most important medical and social problems, due to their high share in the structure of morbidity and mortality of the population, significant indicators of temporary loss of working capacity and primary disability. At the same time, the World Health Organization estimates that by 2021, 615 million people (about 10% of the world's population) will have symptoms of depressive or anxiety disorders. Therefore, the study of the pathogenetic links of comorbidity of anxiety-depressive disorders against the background of ischemi

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4

Arustamian, Olha M., Volodymyr S. Tkachyshyn, Vitalii E. Kondratiuk, Nataliia Yu Tkachyshyna, Oleksandr Yu Aleksiichuk, and Irina V. Dumka. "INFLUENCE OF ADVERSE PRODUCTION FACTORS ON CEREBRAL HEMODYNAMIC IN LOCOMOTIVE DRIVERS." Wiadomości Lekarskie 73, no. 12 (2020): 2617–22. http://dx.doi.org/10.36740/wlek202012111.

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The aim: To investigate the pathological changes in intra- and extra cranial blood vessels in workers of locomotive crews depending on their length of service. Materials and methods: The study involved 249 male patients, aged from 21 to 60 years who worked as locomotive drivers. We used Doppler examination and studied Doppler Indexes of cerebral vessels. Results: Results of examination showed that with increasing length of work of workers of locomotive crews (together with increasing of their age) we have established: 1) Reduction the elasticity of blood vessels (77.6% of the patients); 2) Inc

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5

Kadimova, Sh G. "Estimation of the Functional Condition of a Fetus of Pregnancy in Chronic Pyelonephritis." Annals of the Russian academy of medical sciences 68, no. 12 (2013): 80–82. http://dx.doi.org/10.15690/vramn112.

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Aim of this study was to investigate the condition of the fetus and feto placental system in chronic pyelonephritis by identifying features in the feto- placental blood flow and middle cerebral artery system. Patients and methods. We examined 68 pregnant women with chronic pyelonephritis and 50 healthy pregnant women as a control group . The study conducted a qualitative assessment of fetus and placental blood flow and blood flow in the middle cerebral artery of the fetus . The data on the condition of feto- placental blood flow and blood flow in the middle cerebral artery in the examined preg

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6

Koptev, Vladimir, Vadim Nimaev, and Vladimir Gorchakov. "FEATURES OF AUTOREGULATION OF CEREBRAL BLOOD FLOW IN LYMPHOMAS." Problems in oncology 63, no. 6 (2017): 920–25. http://dx.doi.org/10.37469/0507-3758-2017-63-6-920-925.

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The group of surveyed persons was made by 95 patients with hemoblastoses, of them 40 - with Hodgkin's lymphoma (HL) and 55 - with non-Hodgkin's malignant lymphoma (NHML) before and after a polychemotherapy at different stages of a disease. We investigated blood velocity with autoregulation assessment in the region of a medial cerebral artery by method of transcranial doppler sonography. In addition we did functional tests with calculation of indexes of reactivity. We established decrease in indicators of reactivity at functional tests that reflects restriction of a functional reserve of brain

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7

Susidko, Olena M. "A role of dopplergraphy is in the estimation of the functional state of fetoplacental complex." Perinatology and reproductology: from research to practice 5, no. 1-1 (2025): 32–37. https://doi.org/10.52705/2788-6190-2025-01.1-05.

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The objective: to estimate diagnostic possibilities of dopplergraphy in the estimation of the functional state of fetoplacental complex. Materials and methods. For the study of diagnostic possibilities of dopplergraphy in the estimation of the functional state of fetus 300 women are inspected with a singleton pregnancy, from them 200 somatically healthy women with physiology motion of pregnancy (group of norm) and 100 women with the complicated motion of pregnancy (group of pathology). In the complex of ultrasonic methods researches were included in V-mode, Doppler and actocardiographic. Resea

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8

Izvarina, Olga A., Tatiana O. Nikolaeva, Viktor V. Anikin, Natalia S. Beganskaya, and Nikolai I. Gromnatskiy. "Experience of studying cerebral disorders in women in menopause." Человек и его здоровье 24, no. 4 (2021): 9–16. http://dx.doi.org/10.21626/vestnik/2021-4/02.

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The incidence of arterial hypertension (AH) in women increases significantly with the onset of menopause. Age-related hypoestrogenism leads both to an increase in blood pressure (BP) and to a violation of its daily profile. It can lead to impaired cerebral blood flow. Objective: to study the features of cerebral disorders in women in the perimenopausal period with and without hyper-tension using rheoencephalography, as well as their relationship with some indicators of the daily blood pressure profile. Materials and methods. A clinical and instrumental examination of 190 women in the climacter

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9

Dravitsa, L. V., and E. V. Konoplyanik. "THE EFFECT OF HEMODYNAMIC FACTORS ON THE ONSET AND PROGRESSION OF PRIMARY OPEN-ANGLE GLAUCOMA (literature review, part I)." Health and Ecology Issues, no. 2 (June 28, 2012): 18–23. http://dx.doi.org/10.51523/2708-6011.2012-9-2-3.

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Objective: to systematize the present-day conceptions of the effect of hemodynamic factors at level of the whole organism and cerebral blood flow on the onset and development of primary open-angle glaucoma. Key points: 1. General disorders of vascular blood flow cause local changes in eye hemodynamics with the subsequent development of degenerative processes in eye tissues, including the drainage unit and optic nerve. 2. The common risk factors contributing to the development of glaucoma, include violation of systemic blood flow, i.e. arterial hypotension, hypertension, vasospasm, hemodynamic

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10

Tsyrlin, V. A., N. V. Kuzmenko, and N. G. Pliss. "Hypertension and cognitive disorders: causes and underlying mechanisms." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 24, no. 5 (2018): 496–507. http://dx.doi.org/10.18705/1607-419x-2018-24-5-496-507.

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Arterial hypertension (HTN) is associated with significant changes in the structure of cerebral vessels. There is a close relationship between the functional activity of neurons and the intensity of their blood supply. Vascular dementia is a heterogeneous group of diseases resulting from the pathology of neurons, glia and vessels. Cognitive disorders are the most typical manifestations of brain pathology in vascular dementia and include memory impairment, decreased learning ability, lack of personal opinion, violation of emotional control and social behavior. The article overviews the data on

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11

Shidlovskaya, Tetiana A., Tamara V. Shidlovskaya, Nikolay S. Kozak, Kateryna V. Ovsyanik, and Lyubov G. Petruk. "The peculiarities of hemodynamic violations for patients with combat acoustic trauma and violations in the central departments of auditory analyzer in the dynamics of treatment." OTORHINOLARYNGOLOGY No5(5) 2022, No5(5) 2022 (October 31, 2022): 2–9. http://dx.doi.org/10.37219/2528-8253-2022-5-02.

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The active combat actions in our country resulted in the increasing the risk of occurrence of the acoustics trauma, acubarotrauma. There is an increase of number of cases of combat acoustic trauma in servicemen and now this problem acquires a large value. The objective estimation of cerebral hemodynamics in patients with acoustics trauma, got in battle conditions, is a necessary condition for the effective complex treatment of sensorineural violations of hearing in such patients. Aim: the examination of quantitative and qualitative indexes of rheoencephalography before and after the treatment

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12

Volobuev, A., and P. Romanchuk. "Biophysics of Blood Circulation in Vascular Dementia and Alzheimer’s Disease." Bulletin of Science and Practice 5, no. 4 (2019): 76–102. http://dx.doi.org/10.33619/2414-2948/41/08.

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Modern rational pharmacotherapy allows being provided with a balance of efficacy and safety in clinical geriatrics, which is especially important in patients with neurovascular degeneration, including in the presence of severe forms of vascular comorbidity, requiring multi–component therapy, under the condition of active multidisciplinary and interdepartmental impact. Dementia in its origin is mixed and it is extremely difficult to divide into parts its primary degenerative or vascular component. The differentiated approach is determined by the heterogeneity of the pathological process, which

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13

Akhmatkhanova, L. Kh B., E. A. Kovaleva, I. S. Aliev, et al. "Fentanyl-Induced cerebrocardial syndrome." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 14, no. 2 (2024): 67–72. http://dx.doi.org/10.20340/vmi-rvz.2024.2.clin.6.

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The clinical case is presented to demonstrate the importance of differential diagnosis of cerebral circulation disorders in patients with acute or chronic toxic effects of psychoactive substances. In the presented observation, a 50-year-old patient was taken to the N.V. Sklifosovsky Research Institute of SP with depression of the level of wakefulness to deep deafness, denies the fact of using psychoactive substances when collecting anamnesis, bilateral myosis, diffuse decrease in tone in all extremities. Computed angiotomography of the brain, transcranial dopplerography, magnetic resonance ima

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14

Shidlovskaya, Tetiana A., Tamara V. Shidlovskaya, Nikolay S. Kozak, Kateryna V. Ovsyanik, and Lyubov G. Petruk. "Indicators of rheoencephalography in recurrent acutraumatic lesions in real combat conditions." OTORHINOLARYNGOLOGY, No1-2(5) 2022 (May 11, 2022): 4–10. http://dx.doi.org/10.37219/2528-8253-2022-1-04.

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Topicality: Recurrent acute trauma is common in patients who have received acutrauma in the combat zone. In such patients it is advisable to diagnose cerebral hemodynamic disorders for timely targeted medical care. Objectives of the study: The purpose of the work is to assess the quantitative and qualitative indicators of rheoencephalography in servicemen who received repeated acute trauma in real combat conditions. Materials and methods: We analysed the rheoencephalography of 52 patients with recurrent acute trauma and 15 healthy normal hearing subjects. Results: In the qualitative assessment

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15

Grabovoy, Alexandr, Lilya Yaremenko, and Sergey Shepelev. "EXPRESSION OF SYNAPTOFYSIN AND VEGF IN THE SENSOMOTOR CORTEX DURING THE CAROTID ARTERY LIGATION, THE BRAIN ANTIGEN SENSITIZATION AND THEIR COMBINATIONS." Wiadomości Lekarskie 75, no. 9 (2022): 2256–61. http://dx.doi.org/10.36740/wlek202209214.

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The aim: To study changes of the expression of synaptophysin (Syn) and vascular endothelial growth factor (VEGF) in neurons of the sensorimotor cortex (SMC) to reveal after unilateral ligation of the carotid artery, sensitization with brain antigen and their combination. Materials and methods: Experimental animals – Wistar rats (260-290 g). Experimental models: mobilization of the left common carotid artery, ligation of the indicated artery, sensitization with cerebral antigen, combination of sensitization with cerebral antigen and ligation of the carotid artery. Methods: immunohistochemistry,

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16

Bulgakova, S., P. Romanchuk, and A. Volobuev. "Clinical and Biophysical Principles of Vascular Dementia and Alzheimer's Disease Treatment." Bulletin of Science and Practice 5, no. 5 (2019): 57–72. https://doi.org/10.33619/2414-2948/42/08.

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Biophysics of blood circulation in Alzheimer’s disease is characterized by disorders of laminar blood flow and cerebral hypoperfusion. As a result, failure intracellular metabolism, there is a cascade of changes in neurons associated with the processes of excitotoxicity and oxidant stress, which in turn stimulates amyloidogenesis. Experimental and 25-year observations have shown that the long-existing state of hypoperfusion leads to hippocampal disorders. This process is accompanied by memory impairment, structural changes in the capillaries in the hippocampus, impaired glucose and prote

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Zherebkin, V. V., D. N. Shiyan, I. V. Borzenkova, and P. V. Tkachenko. "Features of morphological changes in articular tissues in vascular diseases of the lower extremities." Morphologia 15, no. 3 (2021): 84–88. http://dx.doi.org/10.26641/1997-9665.2021.3.84-88.

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Background. Big epidemiological studies have revealed a link between osteoarthritis and some cardiovascular diseases such as coronary heart disease, heart failure, cerebral circulation disorders, vascular diseases and diabetes mellitus. Objective. Determination of the features of morphological changes in the synovial membrane of the joint, articular cartilage and subchondral bone in patients with cardiovascular diseases. Methods. Histological studies of articular tissues of 30 amputated lower extremities in persons with vascular diseases of the lower extremities were performed. Results. In all

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18

Krivopalov, Aleksandr A., Aleksandr Yu Shcherbuk, Yurii A. Shcherbuk, Irina I. Sarkisyan, Polina A. Shamkina, and Alexandra I. Glyshchenko. "Cerebral venous thrombosis in otorhinolaryngology. Case report." Consilium Medicum 24, no. 9 (2022): 632–36. http://dx.doi.org/10.26442/20751753.2022.9.201910.

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A violation of cerebral circulation, in which a blood clot forms in the venous system of the brain with the formation of an obstruction of the dural sinus, one or more veins of the brain is called cerebral venous thrombosis. Cerebral venous sinus thrombosis (CVT) is a rare venous thromboembolic event, which accounts for 5 cases per 1 million among adults and about 7 cases per 1 million among children, according to the International Study on Cerebral Vein and Dural Sinus Thrombosis. Women of childbearing age are more susceptible to the disease, which is probably due to hormonal changes during p

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19

Bulgakova, S., P. Romanchuk, and A. Volobuev. "Clinical and Biophysical Principles of Vascular Dementia and Alzheimer’s Disease Treatment." Bulletin of Science and Practice 5, no. 5 (2019): 57–72. http://dx.doi.org/10.33619/2414-2948/42/08.

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Biophysics of blood circulation in Alzheimer’s disease is characterized by disorders of laminar blood flow and cerebral hypoperfusion. As a result, failure intracellular metabolism, there is a cascade of changes in neurons associated with the processes of excitotoxicity and oxidant stress, which in turn stimulates amyloidogenesis. Experimental and 25-year observations have shown that the long-existing state of hypoperfusion leads to hippocampal disorders. This process is accompanied by memory impairment, structural changes in the capillaries in the hippocampus, impaired glucose and protein met

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20

Volosovets, A.O. "Analysis of arterial pressure variability in patients with acute cerebral stroke depending on the time of occurrence." Medicni perspektivi 22, no. 4 (2017): 25–32. https://doi.org/10.26641/2307-0404.2017.4.117663.

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Arterial hypertension can cause a pronounced negative influence on the state of the cerebral vascular system and lead to significant microtraumatization of the walls of the vessels and disruption of vascular autoregulation. This predictor has the greatest influence on the onset of ischemic stroke of atherothrombotic and lacunar subtypes, however, hypertension occurs almost in all patients with acute cerebral ischemia. Interesting and not at all presented in modern scientific literature is the question of the relationship of oscillation of blood pressure with the period of the onset of the focu

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21

Vlasov, A. О. "Modern experience in conducting cerebral oximetry in neonatology: review." Reports of Vinnytsia National Medical University 24, no. 3 (2020): 543–49. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(3)-28.

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Annotation. Near-infrared spectroscopy (NIRS), non-invasive monitoring of tissue oxygenation in many organs, has potentially high diagnostic and prognostic value in critically ill patients. Aim – to analyze modern scientific data on cerebral oximetry by near infrared spectroscopy in neonatal practice. A selective review of literature science data on Internet databases: Pub Med, UpToDate, Medscape EU and Pediatrics was carried out in retrospect. It has been established that understanding neonatal brain oxygenation may be of great clinical importance, since most neonatal pathology is associated

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Martynov, Anatoly I., Evgeniya V. Akatova, Elena I. Pervichko, Olesya P. Nikolin, and Inna V. Urlaeva. "Influence of type A behavioral activity on the development of cardiovascular disease." CardioSomatics 10, no. 4 (2019): 39–43. http://dx.doi.org/10.26442/22217185.2019.4.190670.

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Aim. To study the influence of type of behavioral activity on the development of cardiovascular diseases, to evaluate the effect of type of behavior on the frequency of repeated hospitalizations and fatal outcomes after acute coronary syndrome. Materials and methods. The study included 100 patients with acute coronary syndrome who were subsequently divided into groups according to the main disease - acute myocardial infarction and unstable angina. The median age was 62.09±5.46 years, the therapy according to the underlying disease. All patients had anamnesis of previous and concomitant disease

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23

Васильева, Людмила Валентиновна, Екатерина Юрьевна Суслова, Елена Владимировна Гостева, and Елена Михайловна Толстых. "THE COMBINATIONS OF GENETIC MARKERS OF BLOOD, THAT INFLUENCE ON THE DEVELOPMENT OF COMPLICATIONS OF ARTERIAL HYPERTENSION." СИСТЕМНЫЙ АНАЛИЗ И УПРАВЛЕНИЕ В БИОМЕДИЦИНСКИХ СИСТЕМАХ, no. 3() (September 30, 2020): 54–59. http://dx.doi.org/10.36622/vstu.2020.19.3.006.

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В статье представлены исследования, в результате которых выявлены корреляции между сочетанием генетических маркеров крови (фенотипы гаптоглобина, группы крови, резус-фактор), полиморфизмом генов (альдостерон синтазы CYP11B2, рецептора брадикинина BDKRB2,) у больных с гипертонической болезнью. Исследование рассматривает современные аспекты диагностики, прогрессирование и развитие таких осложнений гипертонической болезни, как транзиторная ишемическая атака, острое нарушение мозгового кровообращения. Изучалось наличием отягощённого семейного анамнеза. В результате проведённого исследования устано

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24

Timakov, A. V., та T. K. Timakova. "Комплексное лечение больных ревматоидным миокардитом коров". Vestnik APK Verhnevolzh`ia, № 2(46) (30 червня 2019): 44–46. http://dx.doi.org/10.35694/yarcx.2019.46.2.009.

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Ревматоидный миокардит у коров протекает остро и характеризуется быстрым развитием клинических симптомов, поражает соединительную ткань сердечнососудистой системы (эндокард, миокард, реже перикард) и крупные суставы. Проявляется как осложнение при инфекционных и гемоспоридиозных болезнях, интоксикациях химическими и медикаментозными ядами, а также при аутоинтоксикациях вследствие поражения кишечника, почек. Воспалительный процесс развивается под воздействием токсинов основного заболевания. Всё это ведёт к нарушению портального кровообращения, развитию застоя крови в печени, кишечнике, легких.

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Maliutina, N. V. "Basic principles of infusion therapy: fundamentals of fluid and electrolyte balance." Infusion & Chemotherapy, no. 3.2 (December 15, 2020): 196–98. http://dx.doi.org/10.32902/2663-0338-2020-3.2-196-198.

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Background. Infusion therapy (IT) is a method of managing the functions of the organism by influencing purposefully the morphological composition and physiological properties of blood through parenteral administration of organic and inorganic solutions. The main feature of IT is that the drug completely enters the bloodstream. Objective. To describe the main characteristics of fluid and electrolyte balance and the IT principles. Materials and methods. Analysis of the literature sources on this topic. Results and discussion. Fluid comprises about 60 % of the human body (in chi

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26

Науменко and E. Naumenko. "Stab wounds to the neck. Treatment in the city hospital. (case study)." Journal of New Medical Technologies. eJournal 8, no. 1 (2014): 0. http://dx.doi.org/10.12737/7383.

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A clinical case study with patients with severe combined stab wounds to the neck and left shoulder. During the operation, the effective intubation wounded carried anesthetist available through a wound on the front of the neck, which communicates with the cavity ro-toglotki. Made a temporary stop bleeding by applying hemostatic zazhi-atoms. Intraoperatively administered broad-spectrum antibiotics. Introduced tetanus anatok-syn. With further audit revealed multiple injuries external jugular veins, facial veins and mandibular artery extending from the external carotid artery. Produced by ligation

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Vorobyev, S. V., S. N. Yanishevskiy, I. V. Kudriavtsev, et al. "Involvement immune response in the pathogenesis of ischemic stroke." Meditsinskiy sovet = Medical Council, no. 3 (April 10, 2023): 8–16. http://dx.doi.org/10.21518/ms2023-024.

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Acute disorders of cerebral circulation are one of the leading problems of modern clinical medicine, due to their significant spread in the human population and the extremely negative impact exerted on the patient’s body. Currently available data allow us to talk about the multi-vector nature of the pathogenesis of ischemic brain damage. Within the framework of the cascade of developing pathochemical and pathophysiological processes, an essential role in the formation of ischemic stroke belongs to the inflammatory reaction occurring through the immune system’s response to cerebral tissue ische

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Rusanova, Dina V., Oleg L. Lakhman, Irina V. Kudaeva, and Natalya G. Kuptsova. "The role of neurotransmitters and indicators of oxidative stress in the formation of disorders of central conductive structures in patients who came into contact with metallic mercury." Russian Journal of Occupational Health and Industrial Ecology 62, no. 12 (2022): 802–8. http://dx.doi.org/10.31089/1026-9428-2022-62-12-802-808.

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Introduction. Studies of toxic lesions due to exposure to metallic mercury compounds do not allow us to identify the features of the violation of central afferent conducting structures in the long-term period of chronic mercury intoxication (CHMI). The contribution of various systems to the development of pathology is not sufficiently disclosed. The study aims to identify the role of neurotransmitters in pathological changes in central hemodynamics, the value of lipid peroxidation products and the activity of antioxidant protection in the demyelination of central afferent conductive structures

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Titov, Evgeny A., N. L. Yakimova, and M. A. Novikov. "ALTERATION OF THE BRAIN AND LIVER TISSUE OF ALBINO RATS WITH LEAD INTOXICATION IN THE DYNAMICS OF THE EXPERIMENT." Hygiene and sanitation 97, no. 10 (2018): 976–78. http://dx.doi.org/10.18821/0016-9900-2018-97-10-976-978.

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Introduction. Lead intoxication is one of the most common intoxications with heavy metals. Lead is a global anthropogenic pollutant. The widespread use of lead in human production activities is the main cause of lead pollution of the environment. Lead is capable of the accumulation in the environment and organisms. Central nervous system, detoxification, and excretion systems and hematopoietic system are the most sensitive to lead exposure. The results of experimental modeling of the toxic effect of lead acetate on the organism of albino rats are presented in this paper. Material and methods.

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Trubilin, V. N., E. G. Poluninа, V. V. Kurenkov, K. V. Chinenova, A. S. Yatsun, and Yu V. Evstigneeva. "Central Retinal Artery Occlusion as a Complication in Invasive Aesthetic Cosmetology: a Clinical Case." Ophthalmology in Russia 18, no. 3 (2021): 584–90. http://dx.doi.org/10.18008/1816-5095-2021-3-584-590.

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Central retinal artery occlusion (CRAO) is a relatively rare form of acute retinal arterial ischemia that results in unilateral vision loss. The incidence of transient vision loss is estimated at approximately 14 cases per 100,000 people per year, while the incidence of CRAO is approximately 1–2 cases per 100,000 people. In the foreign literature, there are more and more publications about the development of iatrogenic vision loss after dermal cosmetic injections. We would like to present a clinical case that should be interesting for both practicing ophthalmologists and specialists of related

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Konovalov, Serhii, Vasyl Moroz, Mykhaylo Yoltukhivskyi, Nataliia Gadzhula, and Alina Stelmashchuk. "THE INFLUENCE OF MESENCHYMAL STROMAL CELLS OF DIFFERENT GENESIS ON ENERGY METABOLISM IN THE RAT SOMATOSENSORY CORTEX DURING ISCHEMIA-REPERFUSION." Eastern Ukrainian Medical Journal 12, no. 3 (2024): 642–50. http://dx.doi.org/10.21272/eumj.2024;12(3):642-650.

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Introduction. About 60-80% of cerebral circulation disorders are due to ischemia, that leads to high mortality, disability in working age and economic burden on society in developed countries of the world. Objective: To investigate the effect of ischemia-reperfusion on parameters of carbohydrate and energy exchanges in the rat somatosensory cortex and to determine the cerebroprotective action of mesenchymal stromal cells (MSCs) of various genesis, MSC lysate and the reference drug Citicoline. Methods. The study was performed on 200 male Wistar rats, divided into 9 groups. Group 1 included inta

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Shabanova, Natalia B., Anastasia D. Gerashchenko, and Marina P. Efremova. "THE EFFECT OF PYRIMIDINE AND CAVINTON DERIVATIVES ON THE CHANGE BIOELECTRIC POTENTIAL IN THE CONDITIONS OF FOCAL CEREBRAL ISCHEMIA OF THE RAT BRAIN." Acta medica Eurasica, no. 1 (March 30, 2023): 101–7. http://dx.doi.org/10.47026/2413-4864-2023-1-101-107.

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Acute disorders of cerebral hemodynamics lead to the development of socially and demographically significant diseases, as a result of which they are one of the main health problems requiring a rational pharmacological approach. In the pathogenesis of pathologies of cerebral circulation, in addition to a decrease in blood flow, an important role is played by a violation of the bioelectric activity of brain tissues, which is evidenced by changes in the frequency and amplitude of oscillations on the encephalogram. Pyrimidine derivatives have proven themselves as potential cerebroprotectors, as a

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Herasym, L., and I. Tsumanets. "EARLY MORPHOGENESIS OF VESSELS AND NERVES OF THE NECK." Clinical anatomy and operative surgery 19, no. 4 (2020): 56–64. http://dx.doi.org/10.24061/1727-0847.19.4.2020.53.

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Carotid artery disease leads to stroke in 30% of cases. The total frequency of carotid artery deformations varies from 10 to 40% depending on the results of angiographic and pathological examinations. Coiling of the internal carotid artery is associated with embryological pathology, and elongation and inflection are the result of fibromuscular dysplasia or changes that are accompanied by atherosclerotic damage to the arteries. Kinking – an artery bend at an acute angle. It can be congenital, when from early childhood there is a violation of cerebral circulation and develops over time from an e

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Nguyen, Tin Hoang, Kien Trung Nguyen, Long Duc Tran, et al. "Characteristics of Rheoencephalography and some associated factors on menopausal women." Journal of Electrical Bioimpedance 13, no. 1 (2022): 78–87. http://dx.doi.org/10.2478/joeb-2022-0012.

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Abstract The significant drop in estrogen levels during menopause increases the cardiovascular risks, one of which is cerebrovascular atherosclerosis. Research on rheoencephalography (REG) parameters for the early diagnosis of cerebrovascular atherosclerotic lesions is of great interest to scientists because of its ease of implementation, low cost, and non-invasiveness. The objectives of study are to evaluate the vascular tone, cerebral circulation flow in each hemisphere of the brain of menopausal women, and some associated factors through waveform characteristics and parameters in REG. A con

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Bereznyakov, V. "The Participation of the Organism Adaptation Mechanisms to the Lack of Oxygen According to the Assessment of the Fethemoglobin Content in the Peripheral Blood of Patients with Community-acquired Pneumonia." Lviv clinical bulletin 2-3, no. 35-36 (2021): 44–49. http://dx.doi.org/10.25040/lkv2021.03-04.044.

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Introduction. Сommunity-acquired pneumonia (COP) is a global socio-medical problem. At emergence of pneumonia by any genesis, hypoxia develops. Oxygen homeostasis of the body is provided by the coordinated interaction of external respiration, circulatory system and oxygen-transport system of the blood. Hypoxia, due to the malfunction of the external respiratory system, causes the formation of compensatory changes, in the implementation of which involved components of the oxygen transport system. Molecular genetic mechanisms play an important role in the body's adaptation to oxygen deficiency.

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Pavlenko, O. Yu, I. G. Strokina, T. I. Drevytska, I. M. Karvatsky, L. M. Sokurenko, and V. E. Dosenko. "Association between risk of ischemic stroke and the rs17216473 single nucleotide polymorphism in the 5-lipoxygenase-activating protein gene locus." Medicni perspektivi 30, no. 1 (2025): 12–21. https://doi.org/10.26641/2307-0404.2025.1.325230.

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Multiple studies have focused on the genetic basis of stroke, in particular on single nucleotide polymorphisms. However, the contribution of single nucleotide polymorphism rs17216473 in the gene that encodes ALOX5AP to stroke has been researched too little. The purpose of the work is to study the association between the risk of ischemic stroke and the single nucleotide polymorphism rs17216473 of the gene that encodes ALOX5AP, in particular, the G/G and G/A genotypes and alleles A and G, within the Ukrainian population. DNA extracted from leukocytes of venous blood of healthy donors (control gr

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Pavlenko, O.Yu., I.G. Strokina, T.I. Drevytska, I.M. Karvatsky, L.M. Sokurenko, and V.E. Dosenko. "Association between risk of ischemic stroke and the rs17216473 single nucleotide polymorphism in the 5-lipoxygenase-activating protein gene locus." Medicni perspektivi 30, no. 1 (2025): 12–21. https://doi.org/10.26641/2307-0404.2025.1.325230.

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Multiple studies have focused on the genetic basis of stroke, in particular on single nucleotide polymorphisms. However, the contribution of single nucleotide polymorphism rs17216473 in the gene that encodes ALOX5AP to stroke has been researched too little. The purpose of the work is to study the association between the risk of ischemic stroke and the single nucleotide polymorphism rs17216473 of the gene that encodes ALOX5AP, in particular, the G/G and G/A genotypes and alleles A and G, within the Ukrainian population. DNA extracted from leukocytes of venous blood of healthy donors (control gr

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Urnova, Evdokia S., Larisa P. Mendeleeva, Olga S. Pokrovskaya, et al. "Hemostatic Disorders and Thrombotic Events in Multiple Myeloma Patients during Peripheral Blood Stem Cell Mobilization." Blood 124, no. 21 (2014): 1131. http://dx.doi.org/10.1182/blood.v124.21.1131.1131.

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Abstract Background: Patients (pts) with multiple myeloma (MM) have an increased risk of thrombosis. Previous studies have shown that 3.7–4.6% of pts undergoing peripheral blood stem cell (PBSC) mobilization developed thrombotic complications. Aims: The aim of the study was to investigate the blood coagulation status in MM pts during PBSC mobilization. Methods: 20 pts: 12 males, 8 females at the age of 27 – 64 years (median 53) were included in the study. After bortezomib-containig induction therapy 5 of them achieved CR, 11 – VGPR and 6 – PR. PBSC mobilization was performed by using cyclophos

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Khasanov, A. Kh, B. A. Bakirov, R. A. Davletshi, L. B. Novikova, and D. A. Kudlay. "Vascular remodeling with violations of intracardiac hemodynamics in patients older age category, combined with the clinical-cluster, neurocognitive and biomarker heterogeneity in multifocal atherosclerosis." Terapevticheskii arkhiv 92, no. 12 (2020): 67–74. http://dx.doi.org/10.26442/00403660.2020.12.200428.

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Aim.Study of the remodeling of the carotid arteries with violation of intracardiac hemodynamics in patients with MFA, and the estimation of the main parameters of dyslipidemia, apoptosis, and oxidative stress in patients with high vascular risk older age group (6175 years) in a Regional vascular center of Ufa. Materials and methods.Depending on the predominant lesion of the vascular pool, patients were divided into 3 clusters by the method of hierarchical analysis of categorical variables according to the clinical manifestation of atherosclerotic lesions of the heart, brain and lower lim

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Kuznetsov, Victor. "New possibilities of multimodal correction of disorders of central nervous system functions in elderly persons." JOURNAL OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE, April 27, 2023, 40–54. http://dx.doi.org/10.37621/jnamsu-2023-1-2-4.

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NEW POSSIBILITIES OF MULTIMODAL CORRECTION OF DISORDERS OF CENTRAL NERVOUS SYSTEM FUNCTIONS IN ELDERLY PERSONS Victor V. Kuznetsov, Serhiy H. Burchynskyi, Kostiantyn O. Apykhtin D. F. Chebotarev Institute of Gerontology of the National Academy of Medical Sciences of Ukraine, 67 Vyshgorodska Str., Kyiv 04114, Ukraine Introduction. The increase in the share of elderly and senile people in the population adds urgency to the problems of various forms of cognitive dysfunction and closely related psycho-emotional disorders and disorders of cerebral circulation. Real success in solving these problems

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Kruchinina, M., A. A. Gromov, V. M. Generalov, A. V. Rabko, and V. N. Kruchinin. "Stroke mechanisms associated with coronavirus disease (COVID-19)." European Heart Journal 42, Supplement_1 (2021). http://dx.doi.org/10.1093/eurheartj/ehab724.1977.

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Abstract The purpose is to identify the pathophysiological mechanisms of stroke development in patients with COVID-19. Methods A total of 92 patients (46.72+1.72 years) with impairments of cerebral circulation due to COVID-19 (confirmed by positive PCR test results) had been examined. Among them, 67 patients had an ischemic stroke, 14–a transient ischaemic attack, 11–an intracerebral hemorrhage, 3– a subarachnoid hemorrhage. The parameters of hemostasis were measured by standard methods, electrical and viscoelastic parameters of red blood cells (RBC) by the dielectrophoresis method was carried

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Horbachovа, S. V., I. F. Bielenichev, and A. V. Abramov. "Influence of thiol antioxidants on manifestation of endothelial dysfunction in cerebral vessels in rats with disturbance of cerebral circulation." Medical and Clinical Chemistry 17, no. 2 (2015). http://dx.doi.org/10.11603/mcch.2410-681x.2015.v17.i2.4861.

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Modelling of brain blood circulation violation by means of bilateral occlusion of the common carotid artery caused the development of stable endothelial dysfunction, which is manifested in the increased level of homocysteine and nitrotyrosine. At the same time there was observed an increase of production of stable metabolites of nitric oxide and increased expression of neuronal and inducible NO-synthase. Holding pharmacotherapy thiotriazoline, α-lipoic acid, tiocetam and angiolin showed the ability of medications in varying degrees depress the manifestations of the endothelial dysfunction of c

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Britton, George L., Tao Peng, Jaroslaw Aronowski, David D. McPherson, Shao-Ling Huang, and Hyunggun Kim. "Abstract 3499: Novel Nitric Oxide-Containing Echogenic Liposome for the Treatment of Vasospasm Following Subarachnoid Hemorrhage." Stroke 43, suppl_1 (2012). http://dx.doi.org/10.1161/str.43.suppl_1.a3499.

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Background: Cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH) is a major cause of high morbidity and mortality. The reduced availability of nitric oxide (NO) in blood and cerebrospinal fluid (CSF) is suggested an important mechanism underlying cerebral vasospasm, a complication of SAH. NO or NO donors are known to have potent effects on cerebral vascular relaxation. We have developed NO-containing echogenic liposomes (NO-ELIP) for NO delivery to assess the role of NO in SAH-induced vasospasm. We hypothesized that NO-ELIP can produce vasodilation and provide an effective the

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Shydlovska, Tetiana A., Mychailo I. Bezega, and Daria M. Kuleshova. "SUDDEN SENSORINEURAL HEARING LOSS IN PATIENTS WITH COVID-19." OTORHINOLARYNGOLOGY, 2024, 69–82. https://doi.org/10.37219/2528-8253-2024-3-69.

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Topicality: The World Health Organization (WHO) claims that the frequency of sensorineural hearing loss is increasing every year. The last time a viral infection can be attributed to the causes of sudden sensorineural deafness Covid-19, because more cases of hearing loss after exposure SARS-CoV-2 described in the literature. One of the forms of sudden sensorineural hearing loss is acute ischemia of the labyrinth owing to a sharp decrease in blood supply cochlea through the labyrinthine artery. This artery has a very small diameter and is extremely sensitive to the processes of blood clotting,

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Bereznyakov, V. "The Participation of the Organism Adaptation Mechanisms to the Lack of Oxygen According to the Assessment of the Fethemoglobin Content in the Peripheral Blood of Patients with Community-acquired Pneumonia." December 21, 2021. https://doi.org/10.25040/lkv2021.03-04.044.

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<strong>Introduction.</strong> Сommunity-acquired pneumonia (COP) is a global socio-medical problem. At emergence of pneumonia by any genesis, hypoxia develops. Oxygen homeostasis of the body is provided by the coordinated interaction of external respiration, circulatory system and oxygen-transport system of the blood. Hypoxia, due to the malfunction of the external respiratory system, causes the formation of compensatory changes, in the implementation of which involved components of the oxygen transport system. Molecular genetic mechanisms play an important role in the body’s adapt

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А.С., Жунуспекова, Мансурова Д.А., Абылхаирова А.К. та Қаражанова Л.К. "ПРОГНОСТИЧЕСКОЕ ЗНАЧЕНИЕ ПОЧЕЧНОЙ ДИСФУНКЦИИ У БОЛЬНЫХИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА ПОСЛЕ РЕВАСКУЛЯРИЗАЦИИ МИОКАРДА". Наука и здравоохранение, № 1(21) (28 лютого 2019). http://dx.doi.org/10.34689/sh.2019.21.1.004.

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Цель исследования. Изучение распространенности почечной дисфункции (ПД) и ее прогностической значимости у больных ишемической болезнью сердца (ИБС), перенесших реваскуляризацию миокарда. Материалы и методы. Проведен одномоментный ретроспективный анализ историй болезни 675 пациентов кардиологического отделения, в анамнезе которых - перенесенное чрескожное коронарное вмешательство (ЧКВ) и/или аортокоронарное шунтирование (АКШ). Изучены распространенность факторов риска, особенности коронарного кровотока, структурно-функциональные изменения сердца. Статистическая обработка проводилась с использов

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