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1
Long, Haiping, and Pengfei Kuang. "Modern Chinese confirmative shi." Functions of Language 24, no. 3 (December 31, 2017): 294–318. http://dx.doi.org/10.1075/fol.15018.lon.
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Abstract Modern Chinese confirmative shi (as in mei cuo, wo shi yao dusi ni (沒錯，我是要毒死你) ‘that’s right. I really wanted to poison you to death’) is not an auxiliary but an adverb. It derives from the adjective shi ‘true, real’ in Old Chinese (Yan zhi yan shi ye (偃之言是也) ‘what Yan said was true’). The grammaticalization pathway of the Modern Chinese confirmative shi is different from that of the copula shi (Laozhang shi huoche siji (老張是貨車司機) ‘Laozhang is a truck driver’) or the auxiliary shi (Laozhang shi kai huoche, wo shi kai keche (老張是開貨車，我是開客車) ‘Laozhang drives a truck and I drive a coach car’). Modern Chinese confirmative shi, copula shi, and auxiliary shi have the same morphological form because they all appear to derive from the adjective shi or demonstrative ( shi ke ren, shu bu ke ren ( 是可忍，孰不可忍) ‘if this could be endured, is there anything else that could not be endured’) in Old Chinese. Such a pattern of morphological sameness seems to be cross-linguistically rare, if not unique.
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Hongye, Fan. "The Association Between Ren Hongjun and Hu Shi." Chinese Studies in History 37, no. 3 (April 2004): 3–33. http://dx.doi.org/10.2753/csh0009-463337033.
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Qiu), Qiu Xiao-ming (X M., and Ding Ning. "Reply to Shi Bing-ren and Qin Yun-wen's Comment." Chinese Physics Letters 14, no. 11 (November 1997): 880. http://dx.doi.org/10.1088/0256-307x/14/11/023.
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So, Francis K. H., Wang Meng-ou (Wnag Meng-ou), Hsieh Hai-p'ing (Xie Hai ping), and Huang Mei-ling. "T'ang-jen hsiao-shuo chiao-shih (Tang ren xiaoshuo jiao shi)." Chinese Literature: Essays, Articles, Reviews (CLEAR) 7, no. 1/2 (July 1985): 209. http://dx.doi.org/10.2307/495213.
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CAO, CHENG-QUAN, JIAN-PING SHI, and ZHAN YIN. "A new species of the genus Chrysacris Zheng, 1983 from China (Orthoptera: Acridoidea, Acrididae)." Zootaxa 4311, no. 3 (August 24, 2017): 443. http://dx.doi.org/10.11646/zootaxa.4311.3.11.
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The Chrysacris Zheng, 1983 is a median genus in Acrididae, which contains 18 species [Tu & Cheng, 1964; Zheng, 1983; Lian & Zheng, 1987; Li & Chen, 1988; Zheng, 1988; Liu, 1990; Ren et al, 1991; Liang & Jia, 1992; Zheng et al, 1992; Ren et al, 1993; Zhang & Zheng, 1993; Zheng, 1993; Zheng & Shi, 1993; Niu, 1994; Ren et al, 1994; Zheng et al, 1995; Yin et al, 1996; Ren 2001; Ren et al, 2002; Yin et al, 2003; Zheng et al, 2011; Dong et al, 2015; Eades, et al, 2017; Zhang et al, 2017], mainly distributed in Heilongjiang, Jilin, Liaoning, Inner Mongolia, Shanxi, Shaanxi, Henan and Guizhou provinces of China. A new species of the genus Chrysacris is described from Inner Mongolia, China in this paper. Type specimens are deposited in the Natural Museum of Hebei University, Baoding, Hebei, China.
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REN, GUO-DONG, and HAO-YU LIU. "A new species of the genus Agnaptoria Reitter from Xizang, China (Coleoptera, Tenebrionidae: Blaptini)." Zootaxa 2169, no. 1 (July 28, 2009): 55–62. http://dx.doi.org/10.11646/zootaxa.2169.1.5.
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The genus Agnaptoria Reitter (1887) from China is studied and a new species is reported, A. nigripes sp. nov. (CHINA, Xizang). The formerly unknown male of A. amdoensis Medvedev (2006) is described for the first time; also, the poorly known male of A. markama Shi & Ren (2005) is redescribed.
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N., W. H., Chou Hsun-ch'u (Zhou Xun chu), Yen Chieh (Yan Jie), Wu Hsiu-ch'eng (Wu Xiu cheng), and Yao Sung (Yao Song). "T'ang-jen i-shih hui-pien (Tang ren yi shi hui bian)." Chinese Literature: Essays, Articles, Reviews (CLEAR) 18 (December 1996): 234. http://dx.doi.org/10.2307/495649.
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Peng, Guozhen. "Chu-Ren Huang & Dingxu Shi, eds., 2016. A Reference Grammar of Chinese." Chinese Language and Discourse 8, no. 1 (September 21, 2017): 130–36. http://dx.doi.org/10.1075/cld.8.1.05pen.
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ZHENG, FANG-QIANG, JIAN-PING SHI, and YAN DANG. "A new species of the genus Mongolotettix Rehn, 1928 from Hubei, China (Acrididae, Acridoidea, Orthoptera)." Zootaxa 4250, no. 2 (April 4, 2017): 198. http://dx.doi.org/10.11646/zootaxa.4250.2.6.
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The genus Mongolotettix Rehn, 1928 is a small genus of family Adrididae. It has nine species discovered from the Far Eastern Asian countries, including China, Japan, Korea, Mongolia, and Russia [Bolívar, 1898; Uvarov, 1914; Caudell, 1921; Chogsomzhav, 1974; Li et Lian, 1994; Wan, Ren et Zhang, 1998; Xie et Li, 2000, Kim et Kim 2005; Dong, et al, 2015; Shi et al, 2016; Storozhenko, 2016; Eades et al, 2017; Zhang et al, 2017]. In the present paper, we describe a new species of the genus from Hubei, China. Type specimens are deposited in the College of Plant Protection, Shandong Agricultural University, Taian, Shandong, China.
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Archibald, S. Bruce, and Vladimir N. Makarkin. "A new genus and species of split-footed lacewings (Neuroptera) from the early Eocene of western Canada and revision of the subfamily affinities of Mesozoic Nymphidae." Canadian Entomologist 152, no. 3 (March 19, 2020): 269–87. http://dx.doi.org/10.4039/tce.2020.10.
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AbstractA new genus and new species of Nymphidae (Neuroptera) is described from the Ypresian Okanagan Highlands locality of Falkland, British Columbia, Canada: Epinesydrion falklandensisnew genus, new species. This is only the fourth known Cenozoic adult specimen, and all others are less complete. It is the second specimen from the Okanagan Highlands. Currently Nymphidae has two recognised subfamilies. All Cenozoic fossils are confident members of the Nymphinae, but the subfamily assignments of almost all Mesozoic genera are problematic. The Late Cretaceous Dactylomyius is the only genus that might belong to Myiodactylinae. The rest may belong to the undefined stem groups of the family or to the Nymphinae, with varying levels of probability. Mesonymphes sibirica is transferred to Nymphites Haase: N. sibiricus (Ponomarenko), new combination; Sialium minor to Spilonymphes Shi, Winterton, and Ren: Spilonymphes minor (Shi, Winterton, and Ren), new combination; “Mesonymphes” apicalis does not belong to Mesonymphes Carpenter and may not even belong to the Nymphidae. The fossil record of the family occurs across much of the globe, but today they are restricted to Australia, New Guinea, and possibly the Philippines. Modern Nymphinae is only found in Australia. This may result from a requirement of frost-free climates, which were more widespread in the past.
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Waley-Cohen, Joanna. "Commemorating War in Eighteenth-Century China." Modern Asian Studies 30, no. 4 (October 1996): 869–99. http://dx.doi.org/10.1017/s0026749x00016826.
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Reviewing his long reign in 1792, the Qianlong Emperor (r. 1736–1795) hailed his military triumphs as one of its central accomplishments. To underscore the importance he ascribed to these successes, he began to style himself ‘Old Man of the Ten Complete Victories’ (Shi Quan Lao Ren), after an essay in which he boldly declared he had surpassed, in ‘Ten Complete Military Victories’ (Shi Quan Wu Gong), the far-reaching westward expansions of the great Han (206 BCE–220 CE) and Tang (618–907) empires. Such an assertion, together with the program of commemoration discussed below, served to justify the immense expense incurred by frequent long-distance campaigning; to elevate all these wars to an unimpeachable level of splendor even though some were distinctly less glorious than others; and to align the Manchu Qing dynasty (16–191 i) with two of the greatest native dynasties of Chinese history and the Qianlong Emperor personally with some of the great figures of the past.
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Zhang, Ye, Elizabeth Strayer, Paddy Bushe, and Jianzhong Yu. "[Yi ge nu ren tong shi ai shang liang ge nan ren] / Ama una mujer a dos hombres? / A Woman loves two men at once?" Sirena: poesia, arte y critica 2005, no. 1 (2005): 44–47. http://dx.doi.org/10.1353/sir.2005.0043.
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Wu, Fatima, Zheng Shusen, Huang Jichi, and Lu Weiluan. "Guo gong nei zhan shi qi Hong Kong ben di ui nan lai wen ren zuo pin xuan." World Literature Today 74, no. 3 (2000): 579. http://dx.doi.org/10.2307/40155852.
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Beongduk Lim. "A study for Shi Wu(士伍) and Shu Ren(庶人) of Qin(秦) and Han(漢)Dynastics." Historical Studies of Ancient and Medieval China ll, no. 20 (August 2008): 325–76. http://dx.doi.org/10.15840/amch.2008..20.011.
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Yue, Lixia, Betsy Navarro, Dejian Ren, Arnolt Ramos, and David E. Clapham. "The Cation Selectivity Filter of the Bacterial Sodium Channel, NaChBac." Journal of General Physiology 120, no. 6 (November 11, 2002): 845–53. http://dx.doi.org/10.1085/jgp.20028699.
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The Bacillus halodurans voltage-gated sodium-selective channel (NaChBac) (Ren, D., B. Navarro, H. Xu, L. Yue, Q. Shi, and D.E. Clapham. 2001b. Science. 294:2372–2375), is an ideal candidate for high resolution structural studies because it can be expressed in mammalian cells and its functional properties studied in detail. It has the added advantage of being a single six transmembrane (6TM) orthologue of a single repeat of mammalian voltage-gated Ca2+ (CaV) and Na+ (NaV) channels. Here we report that six amino acids in the pore domain (LESWAS) participate in the selectivity filter. Replacing the amino acid residues adjacent to glutamatic acid (E) by a negatively charged aspartate (D; LEDWAS) converted the Na+-selective NaChBac to a Ca2+- and Na+-permeant channel. When additional aspartates were incorporated (LDDWAD), the mutant channel resulted in a highly expressing voltage-gated Ca2+-selective conductance.
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Ma, Jin Yeul, Jae Man Yang, Hei Jeung Joo, Mi Young Lee, Jae Hak Park, and Kyu Yong Jung. "Improvement of cerebral ATP and choline deficiencies by Shao-Yin-Ren Shi-Quang-Da-Bu-Tang in senescence-accelerated mouse prone 8." Journal of Ethnopharmacology 67, no. 3 (November 1999): 297–305. http://dx.doi.org/10.1016/s0378-8741(99)00069-0.
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Tun, Ngai Ling, Wu Ju-yu (Wu Ru yu), and Hu K'o-hsien (Hu Ke xian). "Ch'uan T'ang shih jen-ming k'ao (Quan tang shi ren ming kao) [An Identification of the Personal Names in the Ch'uan T'ang shih]." Chinese Literature: Essays, Articles, Reviews (CLEAR) 14 (December 1992): 180. http://dx.doi.org/10.2307/495421.
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Kirejtshuk, Alexander G. "Taxonomic Review of Fossil Coleopterous Families (Insecta, Coleoptera). Suborder Archostemata: Superfamilies Coleopseoidea and Cupedoidea." Geosciences 10, no. 2 (February 17, 2020): 73. http://dx.doi.org/10.3390/geosciences10020073.
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The paper is the first of a series, which aims to present a consistent interpretation of the suprageneric taxa of fossil beetles in the current century and their generic and species composition. Order Coleoptera is considered in composition of the superorder Coleopteroidea Handlirsch, 1903 (= Coleopterida sensu Boudreaux, 1979, nec Pearse, 1936) together with orders Skleroptera and Strepsiptera, and also with the family Umenocoleidae of unclear position. This paper includes the archostematan superfamilies Coleopseoidea and Cupedoidea of the infraorder Cupediformia, i.e., Coleopseidae (one genus and one species), Tshekardocoleidae (12 genera, 15 species), Labradorocoleidae (one genus, one species), Permocupedidae (together with Taldycupedinae, stat. nov., 24 genera and 54 species) and Cupedidae (three subfamilies, 49 genera, 253 species). The preliminary information on structure of the larva of Tshekardocoleidae from Tshekarda is done. There are also described the new taxa: genus Afrotaldycupes Kirejtshuk, gen. nov. with the type species: genus Taldycupes africanus Ponomarenko in Ponomarenko & Mostovski, 2005 [Afrotaldycupes africanus comb. nov.] and Afrotaldycupes lidgettoniensis (Ponomarenko in Ponomarenko & Mostovski, 2005), comb. nov. [Taldycupes]; genus Allophalerus Kirejtshuk, gen. nov. with the type species: Tetraphalerus aphaleratus Ponomarenko, 1969 [Allophalerus aphaleratus comb. nov.], and also with Allophalerus antiquus (Ponomarenko, 1964), comb. nov. [Tetraphalerus], Allophalerus bontsaganensis (Ponomarenko, 1997), comb. nov. [Tetraphalerus], Allophalerus incertus (Ponomarenko, 1969), comb. nov. [Tetraphalerus], Allophalerus latus (Tan, Ren et Shih, 2007), comb. nov. [Tetraphalerus], Allophalerus maximus (Ponomarenko, 1968), comb. nov. [Tetraphalerus], Allophalerus okhotensis (Ponomarenko, 1993), comb. nov. [Tetraphalerus], Allophalerus tenuipes (Ponomarenko, 1964), comb. nov. [Tetraphalerus], Allophalerus verrucosus (Ponomarenko, 1966), comb. nov. [Tetraphalerus]; genus Bukhkalius Kirejtshuk et Jarzembowski, gen. nov. with the type species: Tetraphalerus lindae Jarzembowski, Wang et Zheng, 2017 [Bukhkalius lindae comb. nov.]; genus Burmocoleus Kirejtshuk, gen. nov. with the type species: Burmocoleus prisnyi sp. nov. and Burmocoleus zhiyuani (Liu, Tan, Ślipiński, Jarzembowski, Wang, Ren et Pang, 2017), comb. nov. [Brochocoleus]; genus Cionocups Kirejtshuk, gen. nov. with the type species: Cionocups manukyani sp. nov.; genus Echinocups Kirejtshuk et Jarzembowski, gen. nov. with the type species: Notocupes neli Tihelka, Huang et Cai, 2020 [Echinocups neli comb. nov.], and also Echinocups ohmkuhnlei (Jarzembowski, Wang et Zheng, 2020), comb. nov. [Notocupes] and Echinocups denticollis (Jiang, Li, Song, Shi, Liu, Chen et Kong, 2020), comb. nov. [Notocupes]; genus Jarzembowskops Kirejtshuk, gen. nov. with the type species: Brochocoleus caseyi Jarzembowski, Wang et Zheng, 2016 [Jarzembowskops caseyi comb. nov.]; genus Lobanovia Kirejtshuk, gen. nov. with the type species: Simmondsia permiana Ponomarenko, 2013 [Lobanovia permiana comb. nov.]; genus Pintolla Kirejtshuk, gen. nov. with the type species: Kaltanicupes ponomarenkoi Pinto, 1987 [Pintolla ponomarenkoi comb. nov.]; genus Polyakius Kirejtshuk, gen. nov. with the type species: Polyakius alberti Kirejtshuk, sp. nov. and Polyakius pubescens Kirejtshuk, sp. nov.; Clessidromma zengi Kirejtshuk, sp. nov.; Cupes golovatchi Kirejtshuk, sp. nov.; Cupes legalovi Kirejtshuk, sp. nov.; Cupes lutzi Kirejtshuk, sp. nov.; Cupes nabozhenkoi Kirejtshuk, sp. nov.; Cupes wedmannae Kirejtshuk, sp. nov.; Mallecupes prokini Kirejtshuk, sp. nov. and Omma janetae Kirejtshuk, sp. nov. The new synonymy is established for the generic names Clessidromma Jarzembowski, Wang et Zheng, 2017 and Lepidomma Jarzembowski, Wang et Zheng, 2019, syn. nov. The rank of Cainomerga A. Kirejtshuk, Nel et P. Kirejtshuk, 2016 is elevated from subgeneric to generic. Also other new combinations are proposed: Cainomerga brevicornis (A. Kirejtshuk, Nel et P. Kirejtshuk, 2016), comb. nov. [Mesocupes], Cainomerga fraterna (A. Kirejtshuk, Nel et P. Kirejtshuk, 2016), comb. nov. [Mesocupes], Cainomerga immaculata (Piton, 1940: 194), comb. nov. [Zonabris, Mesocupes], Cainomerga palaeocenica (A. Kirejtshuk, Nel et P. Kirejtshuk, 2016), comb. nov. [Mesocupes], and Cainomerga ponti (A. Kirejtshuk, Nel et P. Kirejtshuk, 2016), comb. nov. [Mesocupes], Clessidromma tianae (Jarzembowski, Wang et Zheng, 2019), comb. nov. [Lepidomma], Diluticupes applanatus (Tan et Ren, 2009), comb. nov. [Brochocoleus], Diluticupes crowsonae (Jarzembowski, Yan, Wang et Zhang. 2013), comb. nov. [Brochocoleus], Diluticupes magnus (Tan et Ren, 2009), comb. nov. [Brochocoleus], Diluticupes minor (Ponomarenko, 2000), comb. nov. [Brochocoleus], Diluticupes validus (Tan et Ren, 2009), comb. nov. [Brochocoleus], Diluticupes yangshuwanziensis (Jarzembowski, Yan, Wang et Zhang. 2013), comb. nov. [Brochocoleus], Monticupes curtinervis (Tan, Ren et Shih, 2007), comb. nov. [Tetraphalerus], Monticupes decorosus (Tan, Wang, Ren et Yang, 2012), comb. nov. [Tetraphalerus], Odontomma sulcatum (Tan, Ren et Shih, 2007), comb. nov. [Brochocoleus], Omma ancistrodontum (Tan, Wang, Ren et Yang, 2012), comb. nov. [Pareuryomma], Omma grande (Ponomarenko, 1964), comb. nov. [Tetraphalerus], Omma longicolle (Ponomarenko, 1997), comb. nov. [Tetraphalerus], Pareuryomma angustum (Tan, Ren et Shich, 2007), comb. nov. [Brochocoleus], Pareuryomma magnum (Tan et Ren, 2009), comb. nov. [Brochocoleus], Zygadenia aliena (Tan et Ren, 2006), comb. nov. [Ovatocupes], Zygadenia baojiatunensis (Hong 1992), comb. nov. [Chengdecupes], Zygadenia brachycephala (Ponomarenko, 1994), comb. nov. [Notocupes], Zygadenia caduca (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia caudata (Ponomarenko, 1966), comb. nov. [Notocupes], Zygadenia cellulosa (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia crassa (Ponomarenko, 1969), comb. nov., [Notocupes], Zygadenia cyclodontus (Tan, Ren, Shih et Ge, 2006), comb. nov. [Amblomma, Notocupes], Zygadenia dischdes (Zhang, 1986), comb. nov. [Notocupes], Notocupes dundulaensis (Ponomarenko, 1994), comb. nov. [Notocupes], Zygadenia elegans (Ponomarenko, 1994), comb. nov. [Notocupes], Zygadenia epicharis (Tan, Ren et Liu, 2005), comb. nov. [Amblomma, Notocupes], Zygadenia eumeura (Tan, Ren et Liu, 2005), comb. nov. [Amblomma, Notocupes], Zygadenia excellens (Ponomarenko, 1966), comb. nov. [Notocupes], Zygadenia exigua (Ponomarenko, 1994), comb. nov. [Notocupes], Zygadenia foersteri (Ponomarenko, 1971), comb. nov. [Procarabus, Notocupes], Zygadenia homora (Lin, 1986), comb. nov. [Conexicoxa, Notocupes], Zygadenia issykkulensis (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia jurassica (Hong 1983), comb. nov. [Chengdecupes], Zygadenia kezuoensis (Hong 1987), comb. nov. [Chengdecupes], Zygadenia khasurtuiensis (Strelnikova, 2019), comb. nov. [Notocupes], Zygadenia khetanensis (Ponomarenko, 1993), comb. nov. [Notocupes], Zygadenia kirghizica (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia laeta (Lin, 1976), [Tetraphalerus], Zygadenia laiyangensis (Hong et Wang, 1990), comb. nov. [Forticupes, Notocupes], Zygadenia lapidaria (Ponomarenko, 1968), comb. nov. [Notocupes], Zygadenia laticella (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia lata (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia lenta (Ren, Lu, Guo et Ji, 1995), comb. nov. [Tetraphalerus], Zygadenia lini (Ponomarenko, Yan, Wang et Zhang, 2012), comb. nov. [Notocupes], Zygadenia longicollis (Ponomarenko, 1994), comb. nov. [Notocupes], Zygadenia ludongensis (Wang et Liu, 1996), comb. nov. [Notocupes], Zygadenia minuscula (Tan, Ren, Shih et Ge, 2006), comb. nov. [Amblomma, Notocupes], Zygadenia mongolica (Ponomarenko, 1994), comb. nov. [Notocupes], Zygadenia nigrimonticola (Ponomarenko, 1968), comb. nov. [Notocupes], Zygadenia oxypyga (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia patula (Ponomarenko, 1985), comb. nov. [Notocupes], Zygadenia pingi (Ponomarenko et Ren, 2010), comb. nov. [Notocupes], Zygadenia porrecta (Tan, Ren, Shih et Ge, 2006), comb. nov. [Amblomma, Notocupes], Zygadenia protensa (Tan, Ren, Shih et Ge, 2006), comb. nov. [Amblomma, Notocupes], Zygodenia psilata (Tan, Ren et Liu, 2005), comb. nov. [Amblomma, Notocupes], , Zygadenia pulchra Ponomarenko, 1968, comb. nov. [Notocupes], Zygadenia reticulata (Oppenheim, 1888), comb. nov. [Procarabus, Notocupes], Notocupes rostrata (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia rudis (Tan, Ren et Liu, 2005), comb. nov. [Amblomma, Notocupes], Zygadenia shiluoensis (Hong 1984), comb. nov. [Chengdecupes], Zygadenia sogutensis (Ponomarenko, 1969), comb. nov., Zygadenia stabilis (Tan, Ren et Liu, 2005), comb. nov. [Amblomma, Notocupes], Zygadenia tenuis (Ponomarenko, 1969), comb. nov. [Notocupes], Zygadenia tripartita (Oppenheim, 1888), comb. nov. [Procarabus, Notocupes], Zygadenia tuanwangensis (Hong et Wang, 1990), comb. nov. [Picticupes, Notocupes], Zygadenia valida (Lin, 1976), comb. nov. [Sinocupes, Notocupes], Zygadenia vitimensis (Ponomarenko, 1966), comb. nov. [Notocupes].
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Furmanik-Kowalska, Magdalena. "Which tradition is mine? Chinese women artists and cultural identity." Journal of Contemporary Chinese Art 6, no. 2 (September 1, 2019): 305–19. http://dx.doi.org/10.1386/jcca_00009_1.
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Abstract References to native culture are frequently in the foreground of works by Chinese women artists. When they make contact with different cultures, although not necessarily connected with leaving their place of birth thanks to the transfer of information and cultural heritage that has developed extremely efficiently in the era of globalization (Gordon Mathews), they see their own entanglement in the cultural tradition. In the process of constructing their identity they try to find answers to the following question: which part of the cultural tradition is mine? Which one do I identify with? In the case of Chinese women artists, is it the legacy of literati? Classic ink painting and calligraphy? Or perhaps women's crafts that bear no name? Or perhaps a mixture of inspirations? Such questions about material heritage might also be augmented by others that consider aspects of the immaterial heritage of China. This article explores how Chinese women artists such as Chen Qingqing, Qin Yufen, Shi Hui, Wang Xiaohui, Cheng Caroline, Lin Tianmiao, Zhang Yanzi, Man Fung-yi, Liu Liyun, Peng Wei, Chen Lingyang, Chen Qiulin, Zhang Ou and Liu Ren refer to their cultural tradition.
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Murray, Judson B. "A Study of “Yao Lue” 要略, “A Sumary of the Essentials”: TheHuainanzi淮南子 from the Point of View of the Postface." Early China 29 (2004): 45–109. http://dx.doi.org/10.1017/s0362502800007094.
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TheHuainanziis a Former Han 前漢 dynasty (202 B.C.E.–9 C.E.) compendium of knowledge written at the court of Huainan and presented to Emperor Wu of the Han 漢武帝 in 139 by Liu An 劉安 (?179–122), the king of Huainan. Liu An was the grandson of the Han “progenitor” Gaozu 高祖 (Liu Bang 劉邦 r. 202–195), and he was the uncle of the reigning emperor Wu (r. 140–87). According to the author(s) of the text’s postface, “Yao lue” 要略 or “A Summary of the Essentials,” the work seeks to provide a comprehensive account or chronicle of thedao道 (conventionally translated as the “Way”), understood broadly to encompass the cosmos (tiandi天地 or “Heaven and Earth”), human beings (ren人) and their affairs (shi事), and the relationship between them. The account of thedaopresented in its chapters is not, however, purely descriptive. TheHuainanziis foremost a political treatise containing instructions worthy of a sage-king (shengwang聖王) to be employed by the ruler as the proper model or standard by which to govern the empire.
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Synthesis and Luminescence Property. "HUANG Jun,SHAO Zhi-meng,REN Yin-bao,ZHAO Qing-er,HONG Jia-dan,WANG Qian,DENG De-gang,YU Hua,XU Shi-qing." Chinese Journal of Luminescence 36, no. 10 (2015): 1126–31. http://dx.doi.org/10.3788/fgxb20153610.1126.
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Chen, Hsing-Yu, Yi-Hsuan Lin, Peck-Foong Thien, Shih-Chieh Chang, Yu-Chun Chen, Su-Shun Lo, Sien-Hung Yang, and Jiun-Liang Chen. "Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/125943.
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Asthma is one of the most common allergic respiratory diseases around the world and places great burden on medical payment. Chinese herbal medicine (CHM) is commonly used for Taiwanese children to control diseases. The aim of this study is to analyze the CHM prescriptions for asthmatic children by using a nationwide clinical database. The National Health Insurance Research Database (NHIRD) was used to perform this study. Medical records from 1997 to 2009 with diagnosis with asthma made for children aged 6 to 18 were included into the analysis. Association rule mining and social network analysis were used to analyze the prevalence of single CHM and its combinations. Ma-Xing-Gan-Shi-Tang (MXGST) was the most commonly used herbal formula (HF) (20.2% of all prescriptions), followed by Xiao-Qing-Long-Tang (13.1%) and Xing-Su-San (12.8%). Zhe Bei Mu is the most frequently used single herb (SH) (14.6%), followed by Xing Ren (10.7%). MXGST was commonly used with Zhe Bei Mu (3.5%) and other single herbs capable of dispelling phlegm. Besides, MXGST was the core formula to relieve asthma. Further studies about efficacy and drug safety are needed for the CHM commonly used for asthma based on the result of this study.
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Maa, Jerome P. Y., K. J. Sun, Z. Shi, L. F. Ren, and L. J. Hamilton. "Discussion of "Acoustic Profiling of Fine Suspension Concentration in the Changjiang Estuary" by Z. Shi, L. F. Ren, and L. J. Hamilton. 1999. "Estuaries" 22:648-656." Estuaries 24, no. 1 (February 2001): 135. http://dx.doi.org/10.2307/1352820.
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Drewniak, Łukasz, and Sabina Drewniak. "The influence of the oxidation method on the properties of reduced graphene oxide." Photonics Letters of Poland 14, no. 3 (September 30, 2022): 47. http://dx.doi.org/10.4302/plp.v14i3.1154.
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Derivatives of graphene have become important materials due to their excellent properties. Graphene oxide and reduced graphene oxide are especially interesting because they are produced relatively easily, cheaply and quickly. Among many possible applications, reduced graphene oxide is a good candidate for sensor applications. Its properties can be controlled at the production stage. The precursor used and the method of oxidation have a significant influence on its properties. Therefore, it is worth take a closer look at them. In this paper we analyse the influence of the oxidation method on the size of the reduced graphene stock which determine the sensitivity of the rGO layer. We used AFM microscopy for this purpose. Full Text: PDF ReferencesS.M. Majhi, A. Mirzaei, H.W. Kim, S.S. Kim, "Reduced Graphene Oxide (rGO)-Loaded Metal-Oxide Nanofiber Gas Sensors: An Overview", Sensors 21, 4 (2021). CrossRef M. Pumera, "Graphene-based nanomaterials for energy storage", Energy Environ. Sci. 4 3 (2011). CrossRef X. Yu, H. Cheng, M. Zhang, Y. Zhao, L. Qu, G. Shi, "Graphene-based smart materials", Nat. Rev. Mater. 2, 9 (2017). CrossRef M.Y. Xia, Y. Xie, C.H. Yu, G.Y. Chen, Y.H. Li, T., Zhang, Q. Peng, "Graphene-based nanomaterials: the promising active agents for antibiotics-independent antibacterial applications", J. Control. Release 10 (2019). CrossRef X. Zhu, Y. Zhou, Y. Guo, H. Ren, C. Gao, "Nitrogen dioxide sensing based on multiple-morphology cuprous oxide mixed structures anchored on reduced graphene oxide nanosheets at room temperature", Nanotechnology 30 45 (2019). CrossRef Z. Wu, Y. Wang, S. Ying, M. Huang, C. Peng, "Fabrication of rGO/Cuprous Oxide Nanocomposites for Gas Sensing", IOP Conf. Ser.: Earth Environ. Sci. 706, 1 (2021). CrossRef S. Pei, H.M. Cheng, "The reduction of graphene oxide", Carbon 50, 9 (2012). CrossRef K. Spilarewicz-Stanek, A. Kisielewska, J. Ginter, K. Bałuszyńska, I. Piwoński, "Elucidation of the function of oxygen moieties on graphene oxide and reduced graphene oxide in the nucleation and growth of silver nanoparticles", RSC Adv. 6, 65 (2016). CrossRef R. Muzyka, S. Drewniak, T. Pustelny, M. Sajdak, Ł. Drewniak, "Characterization of Graphite Oxide and Reduced Graphene Oxide Obtained from Different Graphite Precursors and Oxidized by Different Methods Using Raman Spectroscopy Statistical Analysis", Materials 14, 4 (2021) CrossRef B. Lesiak, G. Trykowski, J. Tóth, et al. "Chemical and structural properties of reduced graphene oxide—dependence on the reducing agent", J Mater. Sci. 56 (2021). CrossRef .
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Kuzmenkin, Alexey, Francisco Bezanilla, and Ana M. Correa. "Gating of the Bacterial Sodium Channel, NaChBac." Journal of General Physiology 124, no. 4 (September 13, 2004): 349–56. http://dx.doi.org/10.1085/jgp.200409139.
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The bacterial sodium channel, NaChBac, from Bacillus halodurans provides an excellent model to study structure–function relationships of voltage-gated ion channels. It can be expressed in mammalian cells for functional studies as well as in bacterial cultures as starting material for protein purification for fine biochemical and biophysical studies. Macroscopic functional properties of NaChBac have been described previously (Ren, D., B. Navarro, H. Xu, L. Yue, Q. Shi, and D.E. Clapham. 2001. Science. 294:2372–2375). In this study, we report gating current properties of NaChBac expressed in COS-1 cells. Upon depolarization of the membrane, gating currents appeared as upward inflections preceding the ionic currents. Gating currents were detectable at −90 mV while holding at −150 mV. Charge–voltage (Q–V) curves showed sigmoidal dependence on voltage with gating charge saturating at −10 mV. Charge movement was shifted by −22 mV relative to the conductance–voltage curve, indicating the presence of more than one closed state. Consistent with this was the Cole-Moore shift of 533 μs observed for a change in preconditioning voltage from −160 to −80 mV. The total gating charge was estimated to be 16 elementary charges per channel. Charge immobilization caused by prolonged depolarization was also observed; Q–V curves were shifted by approximately −60 mV to hyperpolarized potentials when cells were held at 0 mV. The kinetic properties of NaChBac were simulated by simultaneous fit of sodium currents at various voltages to a sequential kinetic model. Gating current kinetics predicted from ionic current experiments resembled the experimental data, indicating that gating currents are coupled to activation of NaChBac and confirming the assertion that this channel undergoes several transitions between closed states before channel opening. The results indicate that NaChBac has several closed states with voltage-dependent transitions between them realized by translocation of gating charge that causes activation of the channel.
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Caro, Denis. "The nexus of transformational leadership of emergency services systems." International Journal of Emergency Services 5, no. 1 (May 3, 2016): 18–33. http://dx.doi.org/10.1108/ijes-11-2015-0024.
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Purpose – In the face of diverse national and international threats, the purpose of this paper is to explore the transformational leadership challenges in emergency services systems in Canada. These adaptive complex systems respond to critical mass emergencies, disasters and catastrophes. Design/methodology/approach – This qualitative research study uses grounded theory to examine the phenomenology of emergency services leadership from systems perspective. Using the theoretical Wu-Shi-Ren (WSR)-Li systems paradigm, this key informant study of 103 emergency leaders from 81 organizations focusses on the systemic challenges that transformational leaders face in emergency services systems. The response rate was 83.5 percent using a semi-structured and open-ended questionnaire. Findings – This key informant study underscores the competencies for transformational leadership and identifies 12 key leadership challenges in the context of the future evolution of emergency services systems. From the use of a grounded theory methodology, the new theory of transcendental transformational emergency leadership is posited. Research limitations/implications – Qualitative studies such as this key informant study underscores the relevance of the WSR-Li systems paradigm and grounded theory approach in discerning leadership challenges that are specific if not unique to emergency services systems. Practical implications – This study underscores the theoretical and pragmatic implications of the transformational leadership challenges for leadership paradigms, innovation and inter-sectorial collaborative networks and possible future emergency services research. Social implications – This study stresses the importance of addressing leadership challenges of emergency services systems as instrumental in ultimately saving lives, minimizing injuries and assuring complete health and social recovery from the scourges of emergency events nationally and internationally. Originality/value – Qualitative studies of the perspectives of strategic emergency leadership of systemic emergency services systems has not hitherto been done in Canada nor internationally. This key informant study underscores the relevance of the WSR-Li systems paradigm and grounded theory approach in discerning transformational leadership challenges that are specific if not unique to emergency services systems. Moreover, from the use of a grounded theory approach, a new theory of transcendental transformational emergency leadership emerged.
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Binh, Phung Thi Xuan, Le Nhu Da, Le Thi Phuong Quynh, Hoang Thi Thu Ha, Duong Thi Thuy, and Le Thi My Hanh. "DNA BARCODING APPLICATION OF MITOCHONDRIAL COI GENE TO IDENTIFY SOME FISH SPECIES OF FAMILY GOBIIDAE IN VIETNAM." Tạp chí Khoa học và Công nghệ biển 18, no. 4 (March 15, 2019): 452–59. http://dx.doi.org/10.15625/1859-3097/18/4/13663.
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The Red river system is a typical example of Southeast Asian rivers that is strongly impacted by human and climatic conditions, especially in the recent period. In this paper, we aim to investigate the longitudinal variation of the water quality of the Red river, in the section from Hanoi city to the Ba Lat estuary. The sampling campaigns were conducted in the dry seasons in 2017 and 2018. The monitoring results showed that the average concentrations of nutrients (NO2-, NO3-, NH4+, PO43-) were still lower than the allowed values of the Vietnamese standard limits for surface water quality (QCVN 08:2015/BTNMT, column A1) whereas the average concentrations of Cl- and TSS exceeded the allowed values of the QCVN 08:2015/BTNMT, column A1 4.6 and 2.3 times, respectively. NO3- and dissolved silica (DSi) concentrations showed a significant variation from the Hanoi site to the Ba Lat site (6.62 mg/l to 1.19 mg/l for NO3- and 5.21 mg/l to 2.14 mg/l for DSi) whereas SO42-, NO2- and Cl- increased markedly in this longitudinal section, especially from the point SH6 where the salinity started to increase. Based on the three different methods for classification of trophic levels and on the different variables observed during the dry seasons in 2017–2018, the nutrient concentrations of the Red river water tended to slightly increase from the site Hanoi (SH1) to the site SH5 at Nam Dinh, indicating the increase of nutrient external input along the river whereas it tended to decrease from the site SH6 (at mesotrophic/eutrophic level) to the last observed site SH9 (at oligotrophic/mesotrophic level) at the sea due to the dilution of seawater. Seawater in dry season could affect directly the river downstream about 35 km far from the sea. The results may be a guide for planning of water use including agricultural irrigation in the Red river estuary.
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Wang, Z., L. Jiaxi, and Y. Liu. "POS1384 DIFFERENT CLINICAL CHARACTERISTICS OF IGG4-RRD PATIENTS AND NON-IGG4-RRD PATIENTS: A LARGE CHINESE COHORT STUDY." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 975.1–975. http://dx.doi.org/10.1136/annrheumdis-2021-eular.4277.
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Background:IgG4-related disease (IgG4-RD) is an autoimmune disorder and frequently involve multiple organs. The respiratory tract is one of the most frequently involved sites.Objectives:This study aimed to compare the demographic and clinical characteristics of IgG4-related respiratory disease (IgG4-RRD) and non-IgG4-RRD patients in a large cohort.Methods:We carried out a retrospective study of 452 cases of IgG4-RD (104 IgG4-RRD patients and 348 non-IgG4-RRD patients) diagnosed at Peking University People’s Hospital between 2003 and 2020.Results:IgG4-RRD patients had an elder age of disease onset and diagnosis. Multiorgan involvement and hypocomplementemia were more common in IgG4-RRD. Besides, the level of ESR, eosinophilia, IgG and IgG4 were higher in IgG4-RRD patients. In IgG4-RRD group, salivary gland, lacrimal gland, lymph nodes, biliary system and kidney were more commonly involved than those in the non-IgG4-RRD group. Also, more numbers of organ involvement and biliary involvement were independent risk factors for the development of respiratory involvement in IgG4-RD patients.Conclusion:Our study revealed demographic, clinical, laboratory and imaging features of IgG4-RRD patients and the underlying differences in pathogenesis between the two phenotypes, which have important implications for the diagnosis and treatment of the disease.References:[1]Morales AT, Cignarella AG, Jabeen IS, Barkin JS, Mirsaeidi M. An update on IgG4-related lung disease. European journal of internal medicine. 2019;66:18-24.[2]Stone JH, Zen Y, Deshpande V. IgG4-related disease. The New England journal of medicine. 2012;366(6):539-51.[3]Vasaitis L. IgG4-related disease: A relatively new concept for clinicians. European journal of internal medicine. 2016;27:1-9.[4]Matsui S, Yamamoto H, Minamoto S, Waseda Y, Mishima M, Kubo K. Proposed diagnostic criteria for IgG4-related respiratory disease. Respiratory investigation. 2016;54(2):130-2.[5]Cao L, Chen YB, Zhao DH, Shi WF, Meng S, Xie LX. Pulmonary function tests findings and their diagnostic value in patients with IgG4-related disease. Journal of thoracic disease. 2017;9(3):547-54.[6]Wallace ZS, Perugino C, Matza M, Deshpande V, Sharma A, Stone JH. Immunoglobulin G4-related Disease. Clinics in chest medicine. 2019;40(3):583-97.[7]Matsui S. IgG4-related respiratory disease. Modern rheumatology. 2019;29(2):251-6.[8]Johansson SG, Hourihane JO, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T, et al. A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force. Allergy. 2001;56(9):813-24.[9]Fei Y, Shi J, Lin W, Chen Y, Feng R, Wu Q, et al. Intrathoracic Involvements of Immunoglobulin G4-Related Sclerosing Disease. Medicine. 2015;94(50):e2150.[10]Wallace ZS, Deshpande V, Mattoo H, Mahajan VS, Kulikova M, Pillai S, et al. IgG4-Related Disease: Clinical and Laboratory Features in One Hundred Twenty-Five Patients. Arthritis & rheumatology (Hoboken, NJ). 2015;67(9):2466-75.[11]Yamada K, Yamamoto M, Saeki T, Mizushima I, Matsui S, Fujisawa Y, et al. New clues to the nature of immunoglobulin G4-related disease: a retrospective Japanese multicenter study of baseline clinical features of 334 cases. Arthritis research & therapy. 2017;19(1):262.[12]Borges T, Silva S. IgG4-related disease: How to place it in the spectrum of immune-mediated and rheumatologic disorders? Modern rheumatology. 2020;30(4):609-16.[13]Liu Y, Xue M, Wang Z, Zeng Q, Ren L, Zhang Y, et al. Salivary gland involvement disparities in clinical characteristics of IgG4-related disease: a retrospective study of 428 patients. Rheumatology (Oxford, England). 2020;59(3):634-40.[14]Matsui S, Taki H, Shinoda K, Suzuki K, Hayashi R, Tobe K, et al. Respiratory involvement in IgG4-related Mikulicz’s disease. Modern rheumatology. 2012;22(1):31-9.Disclosure of Interests:None declared
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Shi, Boyu, Jihyeon Gim, Linze Li, Chongmin Wang, Anh Vu, Jason R. Croy, Michael Thackeray, and Eungje Lee. "Studies of Synthesis Temperature Effects on Cubic Lithated-Spinel to Layered Phase Transformation and Electrochemical Performance of LiMn0.5Ni0.5O2 Cathode Materials." ECS Meeting Abstracts MA2022-02, no. 64 (October 9, 2022): 2337. http://dx.doi.org/10.1149/ma2022-02642337mtgabs.
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Recently, our group has reported a novel Li-ion battery cathode, ‘LT-LiMn0.5Ni0.5O2’, where LT refers to its relatively low synthesis temperature (400 °C). By collecting high energy X-ray diffraction and high-angle, annular-dark-field (HAADF) scanning-transmission electron microscopy (STEM) data, we confirm that the LT-LiMn0.5Ni0.5O2 features a unique partially disordered rock salt structure with predominant lithiated-spinel-like character. The electrochemical data indicates that the Li/LT-LiMn0.5Ni0.5O2 cells shows good cycle stability when operate between 2.5-5.0V. The 1st cycle specific discharge capacity was determined to be 225mAh/g. Two distinct voltage plateaus can be identified at approximately at ~4.6 V and ~3.5 V during discharge. The ~1 voltage separation of the plateaus is caused by the octahedral and tetrahedral site energy difference during lithium extraction and insertion.1 The discovery of LT-LiMn0.5Ni0.5O2 not only expand the compositional space for the known lithated-spinel family but also provide a practical way to increase the operational capacity of traditional spinels such like LiMn2O4 and LiMn1.5Ni0.5O2.2-5 It is well known that when synthesized at 900°C, LiMn0.5Ni0.5O2 features a layered structure.6 The existence of lithated-spinel like LiMn0.5Ni0.5O2 at low temperature (400°C) immediately raise another question: How does the synthesis temperature affect the structure and electrochemical performance of LiMn0.5Ni0.5O2? We synthesized a series of different temperature of LiMn0.5Ni0.5O2 powders. By collecting high energy X-ray diffraction and high-resolution transmission electron microscopy (HR-TEM) data, we confirm that, the LiMn0.5Ni0.5O2 exhibits a lithated spinel → disordered layered → ordered layered structure transformation as temperature increase from 400-900 °C. The Rietveld refinements results also reveals a gradual decrease of the Li/Ni exchange ratio accompanied by the synthesis temperature changes. The evolution of specific discharge capacity for different temperature LiMn0.5Ni0.5O2 shows a parabola-like curve behavior with the lowest discharge capacity at 700 °C. This unique behavior is likely to be related to the diffusion channels reconstruction along with the structure changes. 3D diffusion channels are incorporated with 2D diffusion channels at low temperature (400°C) for lithated-spinel LiMn0.5Ni0.5O2. Within the middle temperature range (500°C-700°C), the 3D channels destroy rapidly while 2D diffusion channels are not well established due to the highly disorder ratio resulting in a decrease of capacity. At higher temperature (800-900°C), the 2D diffusion channels are more well established enabling an increase of the capacity. Shi, B.; Gim, J.; Li, L.; Wang, C.; Vu, A.; Croy, J. R.; Thackeray, M. M.; Lee, E., LT-LiMn 0.5 Ni 0.5 O 2: a unique co-free cathode for high energy Li-ion cells. Chemical Communications 2021, 57 (84), 11009-11012. Thackeray, M. M.; Lee, E.; Shi, B.; Croy, J. R., Review–From LiMn2O4 to Partially-Disordered Li2MnNiO4: The Evolution of Lithiated-Spinel Cathodes for Li-Ion Batteries. Journal of The Electrochemical Society 2022, 169 (2), 020535. Gummow, R.; Thackeray, M.; David, W.; Hull, S., Structure and electrochemistry of lithium cobalt oxide synthesised at 400 C. Materials research bulletin 1992, 27 (3), 327-337. Lee, E.; Blauwkamp, J.; Castro, F. C.; Wu, J.; Dravid, V. P.; Yan, P.; Wang, C.; Kim, S.; Wolverton, C.; Benedek, R., Exploring lithium-cobalt-nickel oxide spinel electrodes for≥ 3.5 V Li-ion cells. ACS applied materials & interfaces 2016, 8 (41), 27720-27729. Lee, E.; Kwon, B. J.; Dogan, F.; Ren, Y.; Croy, J. R.; Thackeray, M. M., Lithiated Spinel LiCo1–x Al x O2 as a Stable Zero-Strain Cathode. ACS Applied Energy Materials 2019, 2 (9), 6170-6175. Yang, X.-Q.; McBreen, J.; Yoon, W.-S.; Grey, C. P., Crystal structure changes of LiMn0. 5Ni0. 5O2 cathode materials during charge and discharge studied by synchrotron based in situ XRD. Electrochemistry communications 2002, 4 (8), 649-654
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Leon, Carlos M., Zheng Gong, Qing Li, Jiayuan Shi, Wulin Zuo, Muneer G. Hasham, Lenny Shultz, Sheng Li, and Guangwen Ren. "Abstract 1863: Mouse strain variations in drug-induced lung stromal responses." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1863. http://dx.doi.org/10.1158/1538-7445.am2022-1863.
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Abstract Chemotherapy has significantly improved the survival of cancer patients. However, the vast variation in treatment responses remains a major issue in the clinic. It is imperative to understand the molecular mechanisms underlying treatment failure in specific populations of patients. Genetic diversity has been recognized to mainly account for the differences in drug responses among patients. Yet, it is not feasible to map the responsible genetic variants within millions of single-nucleotide polymorphisms in the human genome in clinical settings with a limited number of subjects and insufficient genomic information. Genetically diverse mice are an ideal tool to overcome the limitations in clinical studies and model drug responses in hosts that require genetic susceptibility and resistance factors. Recent studies have also implicated a critical role for host cells (i.e., the tissue microenvironment) in building a protective “niche” for tumor cells enabling their escape from chemotherapeutic treatments. Notably, the host regenerative response upon chemotherapy “injury,” which is regarded as an intrinsic host mechanism to repair damaged tissues, may be exploited by tumor cells for their local recurrence or distant metastases. In this study, using a lung injury model, we determined how drug-induced lung stromal wound healing responses differed among eight inbred mouse strains (BALB/cJ, NSG, C57BL/6J, CH3/HeJ, CBA/J, SJL/J, A/J, and NOD/ShiLtJ). Upon either cisplatin or doxorubicin stimulation, the wound healing-associated genes Il-6, Spp1, Cxcl1, and Ccl2 were all found upregulated in lung stromal cells but showed a great variation across different strains. Furthermore, we performed single-cell RNA sequencing on the lung stromal cells and immune cells isolated from three selected mouse strains (BALB/cJ, C57BL/6J, and NOD/ShiLtJ) without and with doxorubicin treatment in vivo. The transcriptomic analyses revealed strain-specific and non-specific therapy-elicited gene signatures in different types of lung tissue cells. Collectively, our results signify an association between genetic backgrounds and drug-induced host responses in mice. The next steps of the study aim to understand how genetic diversity would functionally impact drug-induced lung tissue regeneration, lung inflammation, and post-therapy tumor relapse or metastasis in the lung. Citation Format: Carlos M. Leon, Zheng Gong, Qing Li, Jiayuan Shi, Wulin Zuo, Muneer G. Hasham, Lenny Shultz, Sheng Li, Guangwen Ren. Mouse strain variations in drug-induced lung stromal responses [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1863.
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Shirazimoghadam, Yasaman, Abdel El kharbachi, Yang Hu, Thomas Diemant, Georginan Melinte, and Maximilian Fichtner. "(Digital Presentation) Recent Development of the Cobalt Free and Lithium Rich Manganese Based Disordered Rocksalt Oxyfluorides As a Cathode Material for Lithium Ion Batteries." ECS Meeting Abstracts MA2022-01, no. 2 (July 7, 2022): 365. http://dx.doi.org/10.1149/ma2022-012365mtgabs.
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Recently, new types of cation disordered rocksalt (DRS) have been reported which show good reversibility. In our study we combined the strategy of using high-valent cations with partial substitution of fluorine for oxygen anions in disordered rocksalt-structure phase to achieve optimal Mn2+/Mn4+ double-redox reaction in the composition system Li2MnxTi1-xO2F (1/3 ≤ x ≤ 1). we synthesized 4 different compositions (Li2MnIIIO2F, Li2MnII 1/3MnIII 1/3TiIV 1/3O2F, Li2MnII 1/2TiIV 1/2O2F and Li2MnII 1/3TiIII 1/3TiIV 1/3O2F). Two of them were synthesized for the first time, Li2MnII 1/3MnIII 1/3TiIV 1/3O2F and Li2Mn II 1/3TiIII 1/3TiIV 1/3O2F. By studying the electrochemical properties of different compounds we found that Ti+4 in the structure keeps Mn at the second state of charge, thus enabling a double redox reaction of Mn2+/Mn4+. By investigating the electrochemical properties of all samples we found that the sample with the composition Li2Mn2/3Ti1/3O2F showed the best electrochemical properties with initial high discharge capacity of 227 mAh g-1 in the voltage window of 1.5-4.3 V and 82% of capacity retentionafter 100 cycles. However, fluorination might lead to several issues such as synthesis limitation, lithium diffusion issues due to preferable strong Li-F bonds, etc. thus, two more different samples based on the Li2Mn2/3Ti1/3O2F composition were synthesized and their properties were investigated (Li1.5MnII 1/3MnIII 1/3TiIV 1/3O2F0.5 and Li1.25MnII 1/3MnIII 1/3TiIV 1/3O2F0.25) in order to find the proper amount of fluorine in the structure which promises the electrochemical behavior. In the following the effect of fluorine on lithium diffusion was investigated by ex-situ Raman studies. These studies shed light on the diffusion pathways of lithium ions during charge and discharge process. The structural characteristics are examined using X-ray diffraction patterns, Rietveld refinement, energy-dispersive X-ray spectroscopy and scanning electron microscopy, transmission electron microscopy and Raman spectroscopy. The oxidation states and charge transfer mechanism are also studied further using extended X-ray absorption fine structure and X-ray photoelectron spectroscopy in which the results approve the double redox mechanism of Mn2+/Mn4+ in agreement with Mn-Ti structural charge compensation. The findings pave the way for designing high capacity electrode materials with multi-electron redox reactions. References: [1]: Chen, R.; Ren, S.; Knapp, M.; Wang, D.; Witter, R.; Fichtner, M.; Hahn, H., Disordered Lithium‐Rich Oxyfluoride as a Stable Host for Enhanced Li+ Intercalation Storage. Advanced Energy Materials 2015, 5, (9), 1401814. [2]: Lee, J.; Kitchaev, D. A.; Kwon, D.-H.; Lee, C.-W.; Papp, J. K.; Liu, Y.-S.; Lun, Z.; Clément, R. J.; Shi, T.; McCloskey, B. D., Reversible Mn 2+/Mn 4+ double redox in lithium-excess cathode materials. Nature 2018, 556, (7700), 185-190.
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Xue, Kaiming, and Denis Yu. "(Digital Presentation) A 2.8V Reversible Sn-Li Battery." ECS Meeting Abstracts MA2022-01, no. 1 (July 7, 2022): 80. http://dx.doi.org/10.1149/ma2022-01180mtgabs.
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Tin (Sn) is a metal that is commonly used in our daily life. With the rapid development of lithium-ion battery in the past decades, Sn and its alloy, such as Sn-Cu[1], and Sn-Ni[2], Sn-Co[3] and Sn-Fe[4] have been used as anode for lithium-ion battery because they can undergo alloying/dealloying process with lithium ions and exhibit high capacity and suitable working voltage of about 0.4 V vs. Li/Li+. Sn can also undergo an oxidation reaction to Sn2+, with an electrode potential of about -0.14 V vs. SHE. It is therefore possible to also use Sn as a cathode material. Herein, we are first to demonstrate a metal-metal battery made up of Sn metal as the cathode and Li metal as the anode in organic electrolyte (see Fig. a). Sn foil and Li foil are simply assembled with 3M LiTFSI in dimethoxyethane/propylene carbonate (DME/PC) electrolyte in an Ar-filled glove box to form a pouch cell. During charging, Sn will give out two electrons and dissolves into the electrolyte as Sn2+, while during discharging, the metal ions will be re-deposited onto the cathode. Thus, the energy is stored in the form of Sn2+ in the electrolyte. The charge-discharge curves in Fig. b show that the operating voltage of the battery is about 2.8 V. Since Sn2+ that is dissolved into the electrolyte from the cathode has higher potential than the Li metal anode, any Sn2+ ions cross-over to the anode will be spontaneously reduced, decreasing the efficiency of the battery. To suppress such self-discharge process, an anion exchange membrane based on poly(ionic liquid) polymer coated on common polypropylene separator is adopted. The Sn-Li battery with the modified separator tested in a current rate of 0.2 mA cm-2 with a capacity limitation of 0.1 mAh cm-2 gives an average Coulombic efficiency about 99.5% and can be cycled for more than 1500 cycles(See Fig. c). We found that the stripping/deposition of Sn on the cathode, and its polarization depend strongly on the type of electrolyte used. With 3M LiTFSI in DME/PC electrolyte, the discharge voltage is lowered by about 0.05 V when the current density is increased from 0.2 mA cm-2 to 1 mA cm-2. More results on the factors affecting the charge-discharge performance of Sn-Li batteries will be discussed at the meeting. [1]X. F. Tan, S. D. McDonald, Q. Gu, Y. Hu, L. Wang, S. Matsumura, T. Nishimura, K. Nogita, Journal of Power Sources 2019, 415, 50. [2]H. Zhang, T. Shi, D. J. Wetzel, R. G. Nuzzo, P. V. Braun, Advanced Materials 2016, 28, 742. [3]J. Yang, J. Zhang, X. Zhou, Y. Ren, M. Jiang, J. Tang, ACS Applied Materials & Interfaces 2018, 10, 35216. [4]Z. Lin, X. Lan, X. Xiong, R. Hu, Materials Chemistry Frontiers 2021, 5, 1185. Figure 1
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Rui, Xie, Wu Daidai, Wei Jiangong, Wang Liaoliang, Liu Lihua, Li Wenjing, Wu Gang, and Guo Xudong. "The Enrichment Mechanism of REE at Sulfate and Methane Transition Zone (SMTZ) of the Northern Part of the South China Sea." Geofluids 2022 (February 24, 2022): 1–13. http://dx.doi.org/10.1155/2022/7571792.
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Rare earth elements (REE) are important raw materials for electronic products and green-energy technology and deep-sea sediment as an important potential source of REE mineral. It is of great scientific significance to understand the influence of REE in deep-sea sediments. In this paper, thirty sediments samples and eleven sediments samples were collected at the site SH3 and SH1 of Shenhu area, respectively. The trace elements, major elements, and different Fe-Mn minerals were analyzed to investigate the role of anaerobic oxidation of methane (AOM) in the enrichment of rare earth elements in the marine sediments. The result showed that the content of ∑REE/Ti increased at the top of sulfate and methane transition zone (SMTZ) at site SH1 and SH3. Combined with the analysis of different forms of ferromanganese minerals and the REE patterns, it is inferred that there is little influence of terrigenous input to the REE content. In contrary, the REE-rich carbonate phase and REE-rich Fe-Mn oxides (hydroxides) phase have important contribution of REE enrichment at the top of SMTZ. Meanwhile, the calculations of the quantitative relationship between the REE-rich carbonate phase and REE-rich Fe-Mn oxides (hydroxides) phase also confirm this conclusion. And the AOM caused the decrease of the REE-rich Fe-Mn oxides (hydroxides) phase and increase of the REE-rich carbonate phase. This is the potential explanation of ∑REE/Ti enrichment at the top of SMTZ. This study is of great scientific significance for the study of REE enrichment mechanism in the methane seeps and provided a new sight of REE enrichment mechanism in deep-sea sediments.
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Erdil, Tuncay, and Cigdem Toparli. "(Digital Presentation) The New 2H Hexagonal Double Perovskite Ba2CoMnO6 As a Superior OER Catalyst in Alkaline Media." ECS Meeting Abstracts MA2022-01, no. 34 (July 7, 2022): 1365. http://dx.doi.org/10.1149/ma2022-01341365mtgabs.
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Climate change has stimulated great interest in developing clean and renewable energy conversion and storage solutions. Emerging technologies for solutions, like unitized regenerative fuel cells, metal-air batteries, and water electrolyzers, depend on the reliable catalyst materials suited for long-term application in alkaline environments[1]. In particular, the demanding reaction in these systems is the oxygen evolution reaction involving complex multielectron/proton transfer processes and thus sluggish kinetic.[2] At present, the state-of-the-art OER catalysts are IrO2 and RuO2. However, the high cost and scarcity of these materials severely prevent the wide-scale application of these systems.[3] Perovskite oxide (e.g., single perovskite expressed as ABO3) electrocatalysts are particularly considered next-generation OER catalysts due to their adjustable physicochemical properties and, as a consequence, their catalytic properties by substitution of ions in the A and B sites.[4] Via doping both at A and B site, double perovskite oxides structure can form (AA′B2O5+δ), which were shown to have stable structure during the OER due to proper O p-band center position relative to the Fermi level. The previous research shows that hexagonal perovskites exhibit enhanced catalytic activity rather than cubic or tetragonal perovskites, which is associated with the face-sharing octahedral unit. [5,6] In this work, we systematically investigate doping of parent La2CoMnO6 with Ba to tune the crystal structure and electronic structure. A series of the double perovskites with the chemical formula of La2-xBaxCoMnO6 (x = 0, 0.5, 1.5, 2) were fabricated via the modified Sol-Gel Pechini method. According to Goldschmidt tolerance factor, it is expected that when Ba amount increases in the A site, the crystal structure changes from cubic to hexagonal, which can contribute to electrocatalytic OER activity based above discussions. Furthermore, it is anticipated that increasing Ba content at the A site should result in higher valence state of transition metals due to stabilizing charge balance of the structure. It is widely reported that presence of higher valence state of transition metals is beneficial for OER. The crystal structure was confirmed by combining powder X-ray diffraction (XRD) patterns and selected area electron diffraction (SAED) patterns. The two-layer hexagonal structure of Ba2CoMnO6 (BCM) was further characterized by high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM). The results show doping of Ba into parent La2CoMnO6 resulted in the hexagonal phase formation and BCM achieves a current density of 10 mA cm–2 at a low overpotential of 288 mV and has the highest intrinsic activity in the series of BaxLa2-xCoMnO6 (x = 0, 0.5, 1, 1.5, 2). Furthermore, BCM exhibits outstanding stability of 12 h in a 0.1 M KOH electrolyte. The electronic structure and surface work function values of the catalysts were examined with X-ray photoelectron spectroscopy (XPS). XPS analysis revealed that valence state of Co and Mn increases through Ba amount in the structure, indicating the double perovskite oxide charge balance is maintained. In addition to valence state analysis, we performed work function analysis of the catalysts tested in this work. The result shows work function of the series of BaxLa2-xCoMnO6 (x = 0, 0.5, 1, 1.5, 2) substantially decreases with Ba content. Here, we show that the high intrinsic activity of BCM is not only related with the hexagonal structure and also may be related with exhibiting lower work function value in the series. In addition, our approach presents a new strategy, air quenching method, to synthesize a phase pure 2H-hexagonal double perovskite oxide. [1] Y. Zhou, X. Guan, H. Zhou, K. Ramadoss, S. Adam, H. Liu, S. Lee, H. Shi, M. Tsuchiya, D. Fong and S. Ramanathan, Nature, 534, 231-234 (2016). [2] X. Cui, P. Ren, D. Deng, J. Deng and X. Bao, Energy & Environmental Science, 9, 123-129 (2016). [3] X. Qiu, Y. Zhang, Y. Zhu, C. Long, L. Su, S. Liu and Z. Tang, Advanced Materials, 33, 2001731 (2020). [4] W. Yin, B. Weng, J. Ge, Q. Sun, Z. Li and Y. Yan, Energy & Environmental Science, 12, 442-462 (2019). [5] L. Tang, W. Zhang, D. Lin, Y. Ren, H. Zheng, Q. Luo, L. Wei, H. Liu, J. Chen and K. Tang, Inorganic Chemistry Frontiers, 7, 4488-4497 (2020). [6] C. Chen, G. King, R. M. Dickerson, P. A. Papin, S. Gupta, W. R. Kellogg and G. Wu, Nano Energy, 13, 423-432 (2015).
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Nilsson, Monique B., Yan Yang, Sonia Patel, Simon Heeke, Xiuning Le, Thiru Aruguman, Jacqulyne Robichaux, et al. "Abstract 1827: CD70 is a novel therapeutic target for EGFR mutant NSCLC with acquired, EMT-associated EGFR TKI resistance." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1827. http://dx.doi.org/10.1158/1538-7445.am2022-1827.
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Abstract Approximately 15% of all patients with non-small cell lung cancer (NSCLC) and nearly 35% of Asian patients with NSCLC harbor activating mutations within the epidermal growth factor receptor (EGFR). Although these patients are initially highly sensitive to first or second generation EGFR tyrosine kinase inhibitors (TKIs) including erlotinib or third-generation inhibitors including osimertinib, EGFR TKI-refractory disease inevitably emerges. While therapeutic strategies to target resistant disease that emerges though secondary EGFR mutations or MET amplification have been developed, there remains a void of therapeutic options for patients where resistance occurs through EGFR-independent mechanism such as epithelial to mesenchymal transition (EMT) or transformation to small cell lung cancer (SCLC). To identify cell surface proteins that could be targeted by antibody-based or adoptive cell therapy approaches we interrogated RNAseq data from EGFR mutant NSCLC cell lines (HCC827 and HCC4006) and their associated EGFR TKI resistant variants previously shown to have developed resistance through EMT and filtered gene expression data to include only genes which transcribed proteins localized to the cell surface. We identified CD70 as a being highly upregulated in EGFR TKI resistant cells (p = 7.2e-42). Given that CD70 expression is highly restricted and only transiently expressed on immune cells, CD70 was selected as a top candidate cell surface protein for targeting studies. Western blotting and flow cytometry analysis confirmed CD70 protein levels to be highly upregulated in EGFR TKI resistant cells that had undergone EMT but not in cells harboring secondary EGFR mutations or MET amplifications. We also observed CD70 upregulation in osimertinib-treated drug tolerant persister cells, indicating that CD70 upregulation is an early event in the evolution of TKI resistance. Moreover, patient-derived models of acquired EGFR TKI resistance also exhibited CD70 positivity. Our data also indicated that in EGFR mutant NSCLC cells, CD70 could be upregulated through decreased CD70 promoter methylation as well as by the EMT regulators, transforming growth factor-β (TGF-β) and ZEB1, both of which were upregulated in TKI resistant cells. In EGFR TKI resistant cells, CD70 knockdown impaired cell viability and invasiveness, and stimulation of CD70 using the exogenous binding partner CD27 resulted in activation of AKT and MAPK, pathways known to be re-activated with acquired TKI resistance. CD70-targeting approaches including anti-CD70 antibody drug conjugates (ADCs) and CD70-targeting CAR T cell and CAR NK cells showed promising in vitro and in vivo activity against CD70 positive tumor cells and in osimertinib drug-tolerant persister cells. These results identify CD70 as a novel therapeutic target for EGFR mutant tumors with acquired EGFR TKI resistance that merits further investigation in the clinic. Citation Format: Monique B. Nilsson, Yan Yang, Sonia Patel, Simon Heeke, Xiuning Le, Thiru Aruguman, Jacqulyne Robichaux, Xiaoxing Yu, Alissa Poteete, Xiaoyang Ren, Lixia Diao, Li Shen, Qi Wang, Fahao Zhang, Leticia Campos Clemente, Luisa Solis Soto, Chunhua Shi, Hai Tran, Jason Bock, Jing Wang, Ignacio I. Wistuba, John D. Minna, John V. Heymach. CD70 is a novel therapeutic target for EGFR mutant NSCLC with acquired, EMT-associated EGFR TKI resistance [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1827.
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Schmalzer, Sigrid. "Dui yu lishi, kexuejia you hua shuo: 20 shiji Zhongguo kexuejie de ren yu shi 对于历史,科学家有话说:20世纪中国科学界的人与事 [Scientists Have Something to Say about History: The People and Issues of Twentieth-Century China’s Scientific World]." East Asian Science, Technology and Society 12, no. 1 (March 1, 2018): 109–13. http://dx.doi.org/10.1215/18752160-4280221.
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Winarno, Deny Arifianto, Myrna Adianti, Eva Inaiyah Agustin, Sisca Dina Nur Nahdliyah, Elsyea Adia Tunggadewi, and Ali Suryaperdana Agoes. "INCREASING PUBLIC PARTICIPATION TO PREVENT THE SPREAD OF COVID-19 IN DUKUH KUPANG SURABAYA." Jurnal Layanan Masyarakat (Journal of Public Services) 6, no. 1 (March 30, 2022): 235–43. http://dx.doi.org/10.20473/jlm.v6i1.2022.235-243.
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Novel Coronavirus 2019 (covid-19) is a generation of the coronavirus that humans have never identified. This virus was first reported to cause an outbreak in Wuhan, China, in December 2019. Until now, covid-19 infection cases have been reported in many countries, such as Thailand, Japan, South Korea, Iran, Italy, Germany, and more than 90 countries worldwide. Until November 1, 2020, a total of 412.784 positive cases of covid-19 were recorded, with 341.942 recovered patients and 13.943 deaths in Indonesia. The purpose of this event is to anticipate the spread of Covid-19 by reminding the public to maintain health protocols and other alternatives in preserving health, also increasing body immunity through massage and traditional Indonesian herbal medicine. This event received a good response from the public. It was evidenced by the number of participants exceeding the predetermined quota and enthusiastic in following the speaker's material. The event was a success and was well received by the participants as well as the local government. After following this event, participants can practise the knowledge obtained from the presenters to maintain and protect their health and immunity from Covid-19.
Keywords: Covid-19, Community service, body immunity
DAFTAR PUSTAKA
Amri, Sofan. Iif Khoiru Ahmadi. 2010. Proses Pembelajaran Kreatif dan Inovatif Dalam Kelas: Metode, Landasan Teoritis-Praktis dan Penerapannya. Jakarta: PT. Prestasi Pustakaraya.
Badan Pusat Statistik Kota Surabaya. “Jumlah RT RW Kecamatan Dukuh Pakis Menurut Kelurahan Tahun 2017”. surabayakota.bps.go.id. https://surabayakota.bps.go.id/statictable/2018/04/19/594/jumlah-rt-rw-kecamatan-dukuh-pakis-menurut-kelurahan-tahun-2017.html. (diakses 15 Desember 2020).
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z. 2020. “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China”. Lancet 2020: 395: 497-506. doi: https://doi.org/10.1016/S0140-6736(20)30183-5.
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Komite Penanganan Covid-19 dan Pemulihan Ekonomi Nasional. “Pasien Sembuh Harian Mencapai 4.141 Orang”. covid19.go.id. https://covid19.go.id/berita/pasien-sembuh-harian-mencapai-4141-orang. (diakses 15 Desember 2020).
Kumar, M., & Dwivedi, S. 2020. “Impact of Coronavirus Imposed Lockdown on Indian Population and their Habits”. International Journal of Science and Healthcare Research Vol.5 Issue: 2: April-June 2020. ISSN: 2455-7587.
Li, S., Wang, Y., Xue, J., Zhao, N., & Zhu, T. 2020. “The impact of covid-19 epidemic declaration on psychological consequences: A study on active weibo users”. International Journal of Environmental Research and Public Health, 17(6), 1–9. doi: https://doi.org/10.3390/ijerph17062032.
Pemerintah Kota Surabaya, “Statistik”. lawancovid-19.surabaya.go.id. https://lawancovid-19.surabaya.go.id/visualisasi/graph. (diakses 15 Desember 2020).
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Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P. 2020. “A novel coronavirus from patients with pneumonia in China, 2019”. New England Journal of Medicine 2020: 382: 727-733. doi: 10.1056/NEJMoa2001017
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Tuleushev, Adil Z., Fiona E. Harrison, Artem L. Kozlovskiy, and Maxim V. Zdorovets. "Enhancement of Luminescence of PET Films after Swift Heavy Ion Irradiation." Polymers 15, no. 4 (February 11, 2023): 910. http://dx.doi.org/10.3390/polym15040910.
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The novelty of the study is that the ordering that occurs in a PET film under the action of SHI irradiation manifests itself as an increase in the integral intensity of intrinsic luminescence. The Urbach behaviour of the red shift of the absorption edge is used as a baseline for further analysis of experimental optical transmission spectra of PET films irradiated by swift heavy ions (SHI) previously published by the authors. Negative deviations of the experimental spectra from the Urbach baseline in the visible and UV parts of the spectrum are attributed to enhanced by SHI irradiation intrinsic luminescence. The observed dependence of the integral intensity of luminescence of irradiated PET films on the SHI fluence and ion charge provides further confirmation of the presence of SHI-induced ordering of the molecular structure in SHI latent tracks.
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Schmalzer, Sigrid. "Weimin Xiong;, Kedi Wang. He cheng yi ge dan bai zhi: Jie jing niu yi dao su de ren gong quan he cheng [Synthesize a protein: The story of total synthesis of crystalline insulin project in China]. (Zhongguo jin xian dai ke xue ji shu shi yan jiu cong shu.). 194 pp., figs., bibl., app., index. Jinan: Shandong jiao yu chu ban she [Shandong Education Press], 2005. $25 (paper)." Isis 99, no. 1 (March 2008): 231–32. http://dx.doi.org/10.1086/589404.
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Kalustova, Daria, Vasyl Kornaga, Andrii Rybalochka, Ying-Jie Yu, and Sergiy Valyukh. "Colour temperature tunable RGBW clusters with 3 control channels." Photonics Letters of Poland 12, no. 1 (March 31, 2020): 10. http://dx.doi.org/10.4302/plp.v12i1.968.
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The work is devoted to development of a smart lighting system that is able to change correlated colour temperature and consists of tunable 4-components RGBW clusters controlled via three channels. It is shown that fixing a ratio between the intensities of white and red LEDs at a level of 100:9 enables obtaining high values of colour rendering in a wide range of correlated colour temperatures. A control of 3 from 4 channels simplifies the system. The influence of the red LED on CRI and luminous efficiency is analysed. Full Text: PDF References:J. Gooley, S. Rajaratnam, G. Brainard, R. Kronauer, C. Czeisler and S. Lockley, "Spectral Responses of the Human Circadian System Depend on the Irradiance and Duration of Exposure to Light", Sci Transl Med 2, 31 (2010) [CrossRef]A. Borisuit, F. Linhart, J. Scartexxini, M. Munch, Light Res Technol 47, 192 (2014) [CrossRef]Q. Dai, W. Cai, L. Hao, W Shi and Z. Wang, Light Res Technol 50 (8), 1198-1211 (2017), [CrossRef]V. Kornaga, V. Sorokin, A. Rybalochka, O. Oliinyk and N. Kornaga, Semicond Phys Quantum Electron Optoelectron 18, 302 (2015) [CrossRef]Illuminating Engineering Society, ANSI/IES TM-30-18 IES method for evaluating light source color rendition (2018). New York, NY[DirectLink]Commission International de l'Éclairage, CIE 224:2017 Colour fidelity index for accurate scientific use (2017). Vienna [CrossRef]V. Kornaga, D. Kalustova and O. Oliynyk, Int Sci Conf "Light and power eng: hist, probl, perspect" 6, 43 (2018) [DirectLink]
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Hegel, Robert E. "The Sights and Sounds of Red Cliffs: On Reading Su Shi." Chinese Literature: Essays, Articles, Reviews (CLEAR) 20 (December 1998): 11. http://dx.doi.org/10.2307/495262.
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Sun, Zhiqiang, and Fenrong Liu. "The Inference Pattern Mou in Mohist Logic: A Monotonicity Reasoning View." Roczniki Filozoficzne 68, no. 4 (January 4, 2021): 257–70. http://dx.doi.org/10.18290/rf20684-12.
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Schemat wnioskowania mou w logice mohistycznej
Biorąc za punkt wyjścia monotoniczność rozumowania, artykuł przedstawia systematyczny sposób interpretacji schematu wnioskowania mou w tekstach mohistycznych. Wzięliśmy pod uwagę zarówno perspektywę logiczną. jak i lingwistyczną, zwracając szczególną uwagę na specyfikę klasycznego języka chińskiego, rolę kontekstu i uwzględniając wszelkie możliwe wskazówki pochodzące ze źródłowych tekstów. Poprzez zastosowania reguł monotoniczności sformułowaliśmy jednolitą odpowiedź na pytanie, dlaczego shi er ran są uznawane za rozumowania poprawne, a shi er buran przeciwnie — uznawane są za kontrprzykłady.
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Mehlmann, Lisa M., and Laurinda A. Jaffe. "SH2 domain-mediated activation of an SRC family kinase is not required to initiate Ca2+ release at fertilization in mouse eggs." Reproduction 129, no. 5 (May 2005): 557–64. http://dx.doi.org/10.1530/rep.1.00638.
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SRC family kinases (SFKs) function in initiating Ca2+release at fertilization in several species in the vertebrate evolutionary line, but whether they play a similar role in mammalian fertilization has been uncertain. We investigated this question by first determining which SFK proteins are expressed in mouse eggs, and then measuring Ca2+release at fertilization in the presence of dominant negative inhibitors. FYN and YES proteins were found in mouse eggs, but other SFKs were not detected; based on this, we injected mouse eggs with a mixture of FYN and YES Src homology 2 (SH2) domains. These SH2 domains were effective inhibitors of Ca2+release at fertilization in starfish eggs, but did not inhibit Ca2+release at fertilization in mouse eggs. Thus the mechanism by which sperm initiate Ca2+release in mouse eggs does not depend on SH2 domain-mediated activation of an SFK. We also tested the small molecule SFK inhibitor SU6656, and found that it became compartmentalized in the egg cytoplasm, thus suggesting caution in the use of this inhibitor. Our findings indicate that although the initiation of Ca2+release at fertilization of mammalian eggs occurs by a pathway that has many similarities to that in evolutionarily earlier animal groups, the requirement for SH2 domain-mediated activation of an SFK is not conserved.
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Meng, Li, JinPing Luo, Chunhua Li, and William H. Kinsey. "Role of Src homology 2 domain-mediated PTK signaling in mouse zygotic development." Reproduction 132, no. 3 (September 2006): 413–21. http://dx.doi.org/10.1530/rep.1.01151.
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Fyn and other Src-family kinases play an essential role at several steps during egg activation following fertilization of externally fertilizing species, such as marine invertebrates, fish, and frogs. Recent studies demonstrate that the requirement for Src-family kinases in activation of the mammalian egg is different from lower species, and the objective of this study was to test the role of the Fyn kinase in the mouse egg activated by intracytoplasmic sperm injection (ICSI). An Src homology 2 (SH2) domain containing fusion protein was used to suppress Fyn function in the mouse zygote following ICSI. Eggs injected with the Fyn SH2 domain at an intracellular concentration of 4–8 μM exhibited reduced developmental potential with 100% of the zygotes being arrested following the first or the second cleavage. At higher concentrations, the protein blocked pronuclear congression and the zygotes remained at the pronuclear stage. The SH2 domain had no effect on sperm-induced calcium oscillations in distinct contrast to its effect on the eggs of lower species. The results indicate that the SH2 domain of Fyn kinase plays an important role in pronuclear congression as well as early cleavage events and that this effect appears not to involve disruption of calcium oscillations.
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R??ttinger, Dominik, Hilde Wolf, Helmut K??chenhoff, Karl-Walter Jauch, and Wolfgang H. Hartl. "RED CELL TRANSFUSION." Shock 28, no. 2 (August 2007): 165–71. http://dx.doi.org/10.1097/shk.0b013e31803df84d.
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Sinclair, Kevin D. "Dolly at 25… is she ‘… still goin’ strong?’." Reproduction 162, no. 1 (July 1, 2021): E1—E3. http://dx.doi.org/10.1530/rep-21-0212.
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Migliaccio, Anna Rita F., Carolyn Whitsett, and Giovanni Migliaccio. "Expansion of Red Blood Cells for Transfusion." Blood 116, no. 21 (November 19, 2010): SCI—46—SCI—46. http://dx.doi.org/10.1182/blood.v116.21.sci-46.sci-46.
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Abstract Abstract SCI-46 Blood transfusion, the earliest form of cell replacement therapy, has become indispensable for modern medicine making the safety and adequacy of the blood supply a national priority. The US blood supply is adequate overall because in 2006 the number of blood units collected exceed by 7.8% the number of those transfused. However, issues surrounding blood transfusion, such as sporadic shortages and potential adverse events to recipients (related to changes in red cell physiology during storage and alloimmunization in chronically transfused patients) prompted past and current efforts to develop alternative transfusion products. Recently, the culture conditions to generate erythroid cells have greatly improved making the production of a transfusion product ex-vivo a theoretically possible, although expensive, proposition. This recognition is inspiring several investigators to develop production processes for ex-vivo generation of red cell transfusion products. A proof-of-concept demonstrating that ex-vivo generated red cells protect mice from experimentally induced lethal anemia has been obtained. Alternative sources of stem cells which include human embryonic stem cells (hESC) and induced pluripotency stem cells (iPS), are being explored. Since red cells do not have a nucleus, safety considerations suggest that they may represent the first cell therapy product to be generated from hESC and iPS. In addition, discarded hematopoietic stem cells present in adult and cord blood donations may theoretically generate numbers of red cells ex-vivo sufficient for transfusion. Affordable clinical grade humanized culture media have also been developed. Possible differences in immunological and biological properties of erythroid cells from different sources are under investigation. These differences include size, levels of activity of glycolytic enzymes and carbonic anhydrase, expression of different isozymes, hemoglobin and antigenic profiles (HLA class II antigens). This last aspect is particularly important because ex-vivo expanded red cells pose the same risk for infection and incompatibility as any transfusion product but pose unique antigenic risks. Since expression of blood group antigens is susceptible to post-transcriptional modifications, the ex-vivo expansion process itself may induce antigenic variability. Therefore, even cells generated from completely matched stem cell sources may induce auto-immunity and/or appear incompatible. Regarding the identity of ex-vivo generated red cell transfusion products, a conservative approach would be to define them as “enucleated red cells”. In principle, however, ex-vivo generated erythroblasts may also serve as transfusion product. Since they undergo 4–64 further divisions and reduce iron overload, they may represent a more potent transfusion product for patients that require chronic transfusion. The clinical use of these cells, however, may involve development of specific procedures to facilitate their homing/maturation in the erythroid niches of the recipients. In summary, on the basis of these cost, logistic and safety considerations we hypothesize that the clinical application of ex-vivo expanded erythroblasts will involve in sequence, drug discovery for personalized therapy, systemic drug delivery, genotypically matched transfusion for alloimmunized patients and then transfusion in the general population. Disclosures: No relevant conflicts of interest to declare.
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Ginzburg, Yelena. "The Red Cell: How Erythropoiesis Modulates Hepcidin Expression." Blood 120, no. 21 (November 16, 2012): SCI—24—SCI—24. http://dx.doi.org/10.1182/blood.v120.21.sci-24.sci-24.
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Abstract Abstract SCI-24 Erythroid precursors in the bone marrow require transferrin-bound iron for hemoglobin synthesis. Therefore, it is not surprising that the regulation of erythropoiesis and iron metabolism is interlinked. Iron demand for erythropoiesis is communicated to the iron-regulatory machinery through incompletely understood mechanisms. At the core of systemic iron homeostasis is the peptide hormone hepcidin, restricting cellular iron export to plasma by inducing the endocytosis and proteolysis of ferroportin. Hepcidin, a liver-synthesized peptide hormone, is released in response to increased iron load, and there is early evidence that circulating hepcidin concentrations affect the distribution of iron between the macrophage storage compartment (favored by higher hepcidin concentrations) and parenchymal cells, including cardiac myocytes and hepatocytes (favored by low hepcidin). Furthermore, ferroportin has recently been identified on erythroid precursors. Its purpose in this cell type and its function in the interface between erythropoiesis and iron metabolism are unclear. Additionally, in response to bleeding or the administration of erythropoietin, expansion of erythroid precursors suppresses hepcidin, most likely through one or more mediators released by the bone marrow and acting on hepatocytes. Iron-loading anemias with ineffective erythropoiesis, in particular β-thalassemia, demonstrate the effects of pathological “erythroid regulators” of hepcidin. Although erythrocyte transfusions are the main cause of iron loading in patients who receive them (β-thalassemia major), lethal iron overload is seen also in patients who are rarely or never transfused (β-thalassemia intermedia). Here, iron hyperabsorption is the cause of iron overload and, as in hereditary hemochromatosis, is caused by low hepcidin. Decreased hepcidin expression in β-thalassemia, with concurrent ineffective erythropoiesis and iron overload, indicates that the “erythroid regulator” may play an even more substantial role in iron metabolism than the “stores regulator.” Two members of the bone morphogenetic protein (BMP) family, growth differentiation factor (GDF) 15 and Twisted Gastrulation (TWSG1), have been implicated as candidate bone marrow-derived hepcidin suppressors in β-thalassemia. Neither factor is responsible for the physiologic hepcidin suppression in response to hemorrhage-induced stress erythropoiesis, and the physiologic suppressor is not known. We focus here on the current state of knowledge regarding the regulation of iron metabolism and attempt to elucidate the interface between iron regulation and erythropoiesis using evidence in part derived from animal models of β-thalassemia. A more complete understanding of the coregulation of erythropoiesis and iron metabolism may lay the foundation for improving diagnosis, increasing treatment options, and ultimately impacting the well-being of patients afflicted with different anemias and/or iron overload related-disorders. Disclosures: No relevant conflicts of interest to declare.
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Weisel, John W. "Role of Red Cells in Thrombosis and Hemostasis." Blood 126, no. 23 (December 3, 2015): SCI—39—SCI—39. http://dx.doi.org/10.1182/blood.v126.23.sci-39.sci-39.
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Until recently it has been assumed that red blood cells (RBCs) play mainly a passive role in hemostasis and thrombosis, but now some studies have uncovered several novel roles for them in both of these processes. The best-known effects of RBCs in clotting in vivo are rheological, involving laminar shearing plus aggregation and deformability of RBCs. In addition, RBCs have specific receptors for platelets and fibrin(ogen) that may be involved in thrombosis. Furthermore, in the contraction of blood clots, the trapping of RBCs in the platelet-fibrin network and subsequent physical changes may be important for hemostasis and thrombosis. Contracted blood clots develop a remarkable structure, with a meshwork of fibrin and platelet aggregates on the exterior of the clot and a close-packed, tessellated array of compressed polyhedral RBCs within. The structure and properties of contracted clots vary depending on the relative amounts of platelets, fibrinogen and RBCs and the conditions of clotting. Such close-packed arrays of polyhedral erythrocytes, or polyhedrocytes, have also been observed in human arterial and especially venous thrombi taken from patients. The mechanical nature of this RBC shape change was confirmed by polyhedrocyte formation from the forces of centrifugation of blood without clotting. Many experiments suggest that polyhedrocytes are more prevalent under conditions associated with thrombosis and could be a marker of prothrombotic conditions. Consistent with this hypothesis, RBC membranes have been found to be a major source of exposure of phosphatidylserine, which forms a procoagulant surface to generate thrombin. Platelets (with their cytoskeletal motility proteins) and fibrin(ogen) (as the substrate bridging platelets for contraction) are required to generate the forces necessary to segregate platelets/fibrin from RBCs and to compress these cells into a tightly packed array. Clots formed after puncture of the mouse saphenous vein are composed primarily of polyhedrocytes, suggesting that they may be important in venous hemostasis. Moreover, the permeability of contracted clots is nearly the same as that of the endothelial cell lining, consistent with their functional significance. These results demonstrate how contracted clots form an impermeable barrier important for hemostasis and wound healing and also to restore flow past obstructive thrombi. On the other hand, they also help explain how fibrinolysis is greatly retarded after clots contract, as a result of these striking structural changes. In summary, RBCs may perform a dual role, both helping to stem bleeding but at the same time contributing to thrombosis in a variety of ways, including when the tightly packed array of RBCs in a contracted clot blocks blood flow and resists dissolution. Disclosures No relevant conflicts of interest to declare.
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Ren, Xuemei, Jie Li, Changlun Chen, Yang Gao, Diyun Chen, Minhua Su, Ahmed Alsaedi, and Tasawar Hayat. "Correction: Graphene analogues in aquatic environments and porous media: dispersion, aggregation, deposition and transformation." Environmental Science: Nano 5, no. 6 (2018): 1518. http://dx.doi.org/10.1039/c8en90022a.
Full textAbstract:
Correction for ‘Graphene analogues in aquatic environments and porous media: dispersion, aggregation, deposition and transformation’ by Xuemei Ren et al., Environ. Sci.: Nano, 2018, DOI: 10.1039/c7en01258f.