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Relevant bibliographies by topics / Shmacko

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Academic literature on the topic 'Shmacko'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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Journal articles on the topic "Shmacko"

1

Veziroglu, T. N., V. S. Marinin, and K. R. Umerenkova. "In memory of Yu. F. Shmalko (14.04.1948–12.10.2008)." International Journal of Hydrogen Energy 36, no. 1 (2011): 1370. http://dx.doi.org/10.1016/j.ijhydene.2010.06.083.

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2

Grekov, I. "Arkanology of V.A. Shmakov: a representation of philosophical and esoteric knowledge." HUMANITIES AND SOCIAL-ECONOMIC SCIENCES 111, no. 2 (2020): 30–36. http://dx.doi.org/10.18522/1997-2377-2020-111-2-30-36.

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3

Likhovidova, V. A., and E. V. Ionova. "The effect of arid growing conditions on water deficit and chlorophyll content of the winter wheat varieties with various productivity." Agrarian science, no. 5 (July 17, 2020): 72–75. http://dx.doi.org/10.32634/0869-8155-2020-338-5-72-75.

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Relevance. The current paper has presented the study results of the effect of arid growing conditions on water deficit and foliage pigment (chlorophyll) of winter wheat varieties with various productivity.Methods. The study was conducted in 2017–2019. The objects of study were the winter durum wheat varieties ‘Eyrena’, ‘Yubilyarka’, ‘Yakhont’, ‘Yantarina’, ‘Oniks’, ‘Lazurit’ developed in the FSBSI “Agricultural Research Center “Donskoy”. There have been used such methods in the current study as the testing of varieties on drought tolerance in conditions of simulated drought (“zasushnik”) proposed by V.V. Maimistov (1988); the method of identification of chlorophyll content in winter wheat leaves proposed by I.G. Shmatko (1976); the method of identification of residual water deficit proposed by L.S. Litvinov (1988).Results. According to the study results there have been identified the most stable, productive winter wheat varieties ‘Yantarina’ and ‘Lazurit’, which possess mechanisms of adaptation to the water stress conditions. The varieties ‘Yantarina’ and ‘Lazurit’ also possess large productivity and chlorophyll content, as well as the smallest rise of residual water deficit in the increasing aridity with 169.7 and 159.5 g/m2, 1.4 and 1.9 mg/100 g of raw weight, 24.6 and 25.7%, respectively.

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Valois, Amanda, Rob Davies-Colley, Richard Storey, et al. "Volunteer monitoring as a focus for community engagement in water management in Aotearoa-New Zealand: review and prospects." Water Supply 19, no. 3 (2018): 671–80. http://dx.doi.org/10.2166/ws.2018.116.

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Abstract This article overviews community-based water monitoring (CBWM) in Aotearoa-New Zealand (NZ). CBWM was strongly boosted in NZ around 2000 by the development of the Stream Health Monitoring and Assessment Kit (SHMAK) and the Wai Care community initiative. Reform of freshwater management in NZ may be one driver for renewed interest recently in CBWM. Because professionals perceive volunteer-monitoring data as unreliable, they currently give little support to volunteer monitoring. To address their concern, we compared CBWM with measurements by regional authorities (RAs) – the main water management agencies in NZ. Agreement was encouragingly close for a comprehensive range of variables, including the important state-of-environment (SoE) indicators: visual clarity, Escherichia coli and macroinvertebrates. Community volunteers need and want ongoing professional support and encouragement, and, fortunately, there are important benefits for water management agencies, including engagement of citizens in water management and use of volunteer data. Professional support for CBWM in NZ could include: advice and encouragement, training, database development and quality assurance. Current research and development is focused on improving resources and systems for volunteer monitoring, notably with upgrading of the SHMAK. We are enlisting volunteers, equipped with improved tools and support systems, to assess the benefits of riparian rehabilitation and the suitability of water for swimming.

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ElTayeby, Omar, Todd Eaglin, Malak Abdullah, David Burlinson, Wenwen Dou, and Lixia Yao. "A feasibility study on identifying drinking-related contents in Facebook through mining heterogeneous data." Health Informatics Journal 25, no. 4 (2018): 1756–67. http://dx.doi.org/10.1177/1460458218798084.

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Binge drinking is a severe health problem faced by many US colleges and universities. College students often post drinking-related text and images on social media, portraying their alcohol use as socially desirable. In this project, we investigated the feasibility of mining the heterogeneous data (e.g. text, images, and videos) on Facebook to identify drinking-related contents. We manually annotated 4266 posts during 21 October 2011 and 3 November 2014 from “I’m Shmacked” group on Facebook, where 511 posts were drinking-related. Our machine learning models show that by combining heterogeneous data types, we were able to identify drinking-related posts with an F1-score of 0.81. Prediction models built on text data were more reliable compared to those built on image and video data for predicting drinking-related contents. As the first step of our efforts in this direction, this feasibility study showed promise toward unleashing the potential of mining social media to identify students who binge drink.

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6

Kim, Young S. "Comment on ‘A combined SIF and temperature model of delayed hydride cracking in zirconium materials’, by A.A. Shmakov et al." Computational Materials Science 42, no. 3 (2008): 439–43. http://dx.doi.org/10.1016/j.commatsci.2007.08.005.

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7

Wu, Xiaohong, Yong Zhang, Junping Guo та ін. "MAC30 Knockdown Inhibits Proliferation and Enhance Apoptosis of Gastric Cancer by Suppressing Wnt/β-Cateninsignaling Pathway". Gastroenterology Research and Practice 2020 (21 серпня 2020): 1–11. http://dx.doi.org/10.1155/2020/6358685.

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Gastric cancer is one of the most frequently diagnosed cancer and poses a serious threat to health system in the world. Upregulation of meningioma-associated protein (MAC30) has been found in many solid tumors and can regulate the proliferation, differentiation, and apoptosis of different tumor cells. Quantitative polymerase chain reaction (qPCR) was used to detect the expression of MAC30 in 68 patients with gastric cancer and their adjacent tissues. Lentiviral vector pGCSIL-shMAC30-GFP of the RNA interference (RNAi) of the MAC30 gene was transfected into gastric cancer BGC-823 cell line and the expression of lentivirus label protein GFP was observed via fluorescence microscope, while cell proliferation and apoptosis were determined with flow cytometry and MTT assay, respectively. Also, related protein expressions on Wnt/β-catenin signaling pathway were analyzed by Western blot method. The expression of MAC30 was abnormally elevated in gastric cancer tissues, while interfering of its expression could significantly inhibit the proliferation of gastric cancer BGC-823 cell line. However, the promotion of apoptosis by mitochondrial pathway was mediated by Bax/Bcl-2 upregulation. Present work showed the effect of downregulated MAC30 expression on proliferation and apoptosis of gastric cancer cell through Wnt/β-catenin signaling pathway. Thus, this investigation provides an experimental basis for future development of chemotherapeutic agent on gastric cancer.

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8

Kilroy, Cathy, and Barry J. F. Biggs. "Use of the SHMAK clarity tube for measuring water clarity: Comparison with the black disk method." New Zealand Journal of Marine and Freshwater Research 36, no. 3 (2002): 519–27. http://dx.doi.org/10.1080/00288330.2002.9517107.

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9

Perevedentsev, V. I. "Economic aspects of public health alteration. Review of the book “Public Health and the Economy” by B. B. Prokhorov, I. V. Gorshkova, D. I. Shmakov, and E. V. Tarasova; ed. by B. B. Prokhorov (MAKS Press, Moscow, 2007)." Studies on Russian Economic Development 19, no. 3 (2008): 321–24. http://dx.doi.org/10.1134/s107570070803012x.

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10

Yang, Yijun, Manujendra N. Saha, Yan Chen, Lugui Qiu, Donna E. Reece, and Hong Chang. "Novel Targeting Of Phospho-Marcks Overcomes Drug Resistance and Induces Anti-Tumor Activity In Preclinical Models Of Multiple Myeloma." Blood 122, no. 21 (2013): 282. http://dx.doi.org/10.1182/blood.v122.21.282.282.

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Abstract Multiple myeloma (MM) remains incurable due to the development of a drug-resistant phenotype after prolonged therapy. Myristoylated alanine-rich C-kinase substrate (MARCKS) is a protein kinase C (PKC) substrate that plays an important role in cell adhesion, spreading and invasion. Our previous studies found that overexpression of phospho-MARCKS (pMARCKS) was detected in developed drug resistant MM cell lines (RPMI-8226 R5, MM.1R) relative to their parental drug sensitive cell lines (RPMI-8226S, MM.1S). We hypothesized that pMARCKS is involved in chemo- and novel drug resistance in MM. To further evaluate the drug resistance, we exposed both RPMI-8226 R5 and MM.1R cell lines to varying dosages of bortezomib, dexamethasone, doxorubicin, and lenalidomide. By MTT assay, both resistant cell lines were found to have significantly higher viability to all 4 drugs compared to their respective non-resistant lines. In addition, Western blot analysis showed increased pMARCKS expressions in all 3 bortezomib resistant cell lines 8226.BR, OPM2.BR, and ANBL-6.BR as compared to their respective bortezomib sensitive cell lines. We next acquired MM patient samples collected at diagnosis and at relapse after bortezomib treatment, and investigated their pMARCKS expression with immunoblotting analyses. The patient samples collected from relapse after bortezomib treatment had higher pMARCKS expression than those collected at diagnosis. Furthermore, we studied additional 3 primary MM patient samples with high pMARCKS expressions and 3 with low expressions for their vaibility after a 36 hour bortezomib treatment, and found that the samples with high pMARCKS expressions were more resistant to bortezomib than those with low pMARCKS expressions (mean IC50 of 7.1 nM and mean IC50 of 4.8 nM, respectively; p = 0.042). Importantly, combination of a low dosage of bortezomib (5.0 nM) with either 2.5 uM or 5.0 uM of enzastaurin (an inhibitor of phospho-PKC), displayed a synergistic cytotoxicity on myeloma cells with high pMARCKS expressions. To further elucidate the role of pMARCKS in drug resistance, we knocked down pMARCKS expression by transfecting siMARCKS into 8226 R5 and MM.1R cells. Following the knockdown, both cell lines had significantly lower viability after treatment with either bortezomib, dexamethasone, doxorubicin, or lenolidomide, in comparison to empty vector controls. FACS analysis and annexin V assay of the knockdown cells and the control cells from both cell lines showed significantly induction of G1/S cell cycle arrest and apoptosis in the knockdown cells. The immunoprecipitation (IP) and chromatin immunoprecipitation (ChIP) DNA-qPCR analysis further demonstrated that pMARCKS regulates SKP2 expression through binding with E2F1, mediating SKP2/p27Kip1 cell cycle pathway. Finally, we investigated the effect of inhibition of pMARCKS in a 8226 R5 xenograft model of SCID mice. Mice injected with shMARCKS-transfected 8226 R5 cells and received bortezomib showed significant retardation of tumor growth and prolonged survival compared to the control groups. Taken together, our data indicate that pMARCKS is constitutively activated in resistant and relapsed MM cells and contributes to drug resistance by regulating E2F1 mediated SKP2/p27Kip1 cell cycle pathway, thus providing a preclinical rationale for targeting pMARCKS as a promising approach in patients with refractory/relapsed MM. Disclosures: Reece: BMS: Research Funding; Celgene: Honoraria, Research Funding; Janssen: Honoraria, Research Funding; Merck: Honoraria, Research Funding; Millennium: Research Funding; Novartis: Honoraria; Onyx: Honoraria.

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Dissertations / Theses on the topic "Shmacko"

1

Shmanko, Kateryna [Verfasser]. "Einflussfaktoren auf den Verlauf einer Terlipressin-Therapie bei gastrointestinaler, portal-hypertensiv bedingter Blutung / Kateryna Shmanko." Mainz : Universitätsbibliothek der Johannes Gutenberg-Universität Mainz, 2021. http://d-nb.info/1238780245/34.

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2

Wikene, Håkon Opsvik. "Implementing a Bare-Metal Threading Library for SHMAC." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for datateknikk og informasjonsvitenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-27037.

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For decades, Moore's Law has stood as a symbol of the continuedperformance increases achieved through technology scaling. While Moore'sobservation has remained true for far longer than Moore himselfpredicted, it now seems to be coming to an end. The move to multi-coreprocessors was motivated by thermal challenges, but is by no means afinal solution. Heterogeneous systems could potentially achieve fargreater energy efficiency than symmetric, multi-core architectures.SHMAC is an FPGA-based architecture that intends to serve as a platformfor exploring the inherent challenges of heterogeneous, single-ISAsystems.Since working with parallel applications on bare-metal platforms can bedifficult, a higher level of abstraction is often preferable. One suchabstraction that is familiar to most developers is the POSIX threadsAPI. This thesis covers the implementation of a bare-metal Pthreadslibrary that provides both threading and several other synchronizationprimitives, such as condition variables, mutexes and barriers. Theimplemented library is used to port several benchmarks from the PARSECsuite; the results from these are presented both to showcase the currentperformance of the platform and the capabilities of the Pthreads library.As a result of the need to verify the correctness and performance of theimplemented library, the need for another tool arose: a profiler. Sincenone currently existed for SHMAC, one had to be written from scratch. Afully functional and gprof-compatible profiler was developed.The features, implementation details and usage of this profiler isdescribed here as well.Two other contributions to the SHMAC project were made as well. Thesewere intended to simplify the task of setting up a working developmentenvironment and the day-to-day work with SHMAC, respectively. Both ofthese will be presented in this thesis.

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3

Akre, Anders Tvetmarken, and Sebastian Bøe. "Turbo Amber : A high-performance processor core for SHMAC." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for datateknikk og informasjonsvitenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-27043.

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The performance increase of state of the art processors has stagnated dueto power and thermal constraints. Heterogeneous computing has latelyattracted interest and may be the key for improving the performanceand energy-efficiency of computing systems under their tight physicalbudgets. The Single-ISA Heterogeneous MAny-core Computer (SHMAC)project is a research project that seeks to explore the challenges ofheterogeneous computing. Therefore, the SHMAC project requires adiversity of processor cores of different size and performance, to exploreheterogeneous architectures.Currently, there is only one processor core, Amber, available for SHMAC.This thesis presents the development of Turbo Amber (TA), a high-performance processor core for SHMAC. We present an overview of high-performance processor architecture techniques and extend the existingAmber core with a branch predictor, a return address stack, an instructionqueue and a fast multiplier. The front-end of TA is capable of fetchingand performing branch prediction on up to four instructions each clockcycle and can be extended with an appropriate back-end for superscalarexecution.Our results show that TA has a performance increase of 49% over theoriginal Amber core, with a moderate increase in FPGA resource utiliza-tion: slice utilization from 4.7% to 7.9%, block RAM utilization from1.0% to 3.3%, and no DSP slices used on a Xilinx Virtex-5 FPGA. TAhas also been integrated into the existing SHMAC-infrastructure andverified by running applications on top of Linux and freeRTOS.

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Books on the topic "Shmacko"

1

Levashov, Viktor. M. Shmakov. Sovetskiĭ khudozhnik, 1987.

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2

Levashov, Vladimir. M. Shmakov. Sov. Khudozhnik, 1987.

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3

Golovanov, N. N. Mark Aleksandrovich Shmakov. Khudozhnik, 1988.

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4

A, Urvalov V., ред. Pavel Vasilʹevich Shmakov. 1885-1982. Nauka, 2002.

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5

Kolmos, Keith. Knockout Kings 2000. Prima Games, Prima Publishing, 1999.

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Knockout Kings 2000: Prima's Official Strategy Guide. Prima Publishing, 1999.

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