Relevant bibliographies by topics / Shona novels

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Shona novels'

Author: Grafiati
Published: 4 June 2021
Last updated: 16 February 2022

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Journal articles on the topic "Shona novels"

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Mavesera, Miidzo, and Davie E. Mutasa. "Empowerment through indigenous literature: The case of Shona novels." South African Journal of African Languages 29, no. 1 (January 2009): 74–86. http://dx.doi.org/10.1080/02572117.2009.10587318.

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Mutasa, D. E., and W. L. Chigidi. "Black writers’ Shona novels of the liberation war in Zimbabwe: an art that tells the truth of its day." Literator 31, no. 2 (July 13, 2010): 61–82. http://dx.doi.org/10.4102/lit.v31i2.47.

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Over the years Shona fiction that portrays Zimbabwe’s liberation war has been a subject of severe criticism because of its tendency to falsify and distort history. This article attempts to provide answers to the question of why authors of Shona war fiction tended to romanticise the war of liberation. In pursuance of this objective this article looks at circumstances and conditions that prevailed at the time that most of the Shona stories about Zimbabwe’s liberation war were written. These stories were published during the first decade of Zimbabwe’s independence and it is possible to look at this time and come up with a set of interdependent cultural, economic, political and ideological conditions that helped to shape writers’ perspectives on the war. The article argues that the conditions of artistic freedom that interfaced with internalised fear, the euphoria and celebration, the dominant ideology of the time, as well as the situation of competition were responsible for shaping the consciousness of the war fiction writers. In this article views expressed in interviews by some of the writers of Shona war fiction are taken into consideration. All interviews with authors referred to in the article were carried out by the researcher.
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Flora Veit-Wild. "Hearing Voices: The Linguistic and Narrative Design of Three Eminent Shona Novels." Research in African Literatures 48, no. 1 (2017): 1. http://dx.doi.org/10.2979/reseafrilite.48.1.02.

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Hassanin, Shaimaa Mohamed Mohamed. "The Influence of Rhodesia Literature Bureau on the Shona literature in Selected Zimbabwean Novels." مجلة القراءة والمعرفة 20, no. 1 (March 1, 2020): 1–21. http://dx.doi.org/10.21608/mrk.2020.100656.

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Makaudze, Godwin. "The Journey Back: Ambivalent (Re)Presentations of Pre-Colonial Women in Post-Independent Shona Novels." Journal of Literary Studies 35, no. 3 (July 3, 2019): 19–31. http://dx.doi.org/10.1080/02564718.2019.1657279.

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N., Eunitah Viriri, and Viriri Maradze. "The teaching Of Unhu/Ubuntu through Shona novels in Zimbabwean secondary schools: A case for Masvingo urban district." Journal of African Studies and Development 10, no. 8 (October 31, 2018): 101–14. http://dx.doi.org/10.5897/jasd2018.0508.

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Beach, D. N. "An Innocent Woman, Unjustly Accused? Charwe, Medium of the Nehanda Mhondoro Spirit, and the 1896–97 Central Shona Rising in Zimbabwe." History in Africa 25 (1998): 27–54. http://dx.doi.org/10.2307/3172179.

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The rising of the Ndebele and southwestern and central Shona people against colonial rule in the 1890s has become one of the classic cases of such resistance. Yet, since the independence of Zimbabwe in 1980, very little fresh research has been carried out on the subject. This paper re-examines the role of Shona religious authorities in the rising, especially that of the medium of the Nehanda spirit of the Mazowe valley in the central Shona area. In just over a century, the figure of “Mbuya Nehanda” has become the best-known popular symbol of resistance to colonial rule in modern Zimbabwe. She has been commemorated since 1980 in statues, street names, a hospital, posters, songs, novels, and poems, and is soon to be the subject of a full-length feature film. This paper examines the historical basis behind the legend.This legend runs as follows: the historical “Nehanda” was supposed to have been the daughter of the founding ancestor of the Mutapa dynasty, who lived in the fifteenth century. Her ritual incest with her brother Matope gave supernatural sanction to the power of the Mutapa state. After her death, she became a mhondoro spirit, and this spirit possessed a number of mediums (masvikiro, singular svikiro). During periods of possession by the spirit, the svikiro was regarded as speaking with the voice and personality of the original Nehanda and not with her own. In the last part of the nineteenth century one medium, Charwe, was responsible for the organization of resistance to the government of the British South Africa Company and the settlers in the Mazowe valley, and in particular for the killing of H.H. Pollard, Kunyaira, the extremely oppressive Native Commissioner of the area. This resistance began in June 1896, and from then until her capture in late 1897 the Nehanda medium was a major factor in the war. Tried and sentenced to death in March 1898, she refused to convert to Christianity and struggled right up to the moment when she was hanged.
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Mutasa, D. E., and I. Mutawi. "A philosophical interpretation of the significance of oral forms in I. Mabasa’s novel Mapenzi (1999)." Literator 29, no. 3 (July 25, 2008): 157–80. http://dx.doi.org/10.4102/lit.v29i3.130.

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The article critically analyses the use of Shona oral art forms in I. Mabasa’s novel “Mapenzi” (“Mad people”/“Foolish people”). It departs from the realisation that the writer identifies with Shona people’s oral experiences in the form of songs, “bembera” (satiric poetry) and folktales among others. These oral art forms provide the means by which the writer overcomes both selfcensorship and real or imagined state censorship. The article advances the argument that Mabasa uses the Shona people’s oral art forms in a manner that is ideologically and pedagogically empowering. This is consistent with the value thrust of Shona people’s epistemological assumptions. The article comes to the conclusion that Mabasa’s vision in the novel “Mapenzi” maintains the line between tradition and continuity.
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Huang, Ming-Shyan, Ya-Ling Hsu, I.-Jeng Yeh, Kuan-Ting Liu, and Meng-Chi Yen. "The Expression Profile of mRNA and tRNA Genes in Splenocytes and Neutrophils after In Vivo Delivery of Antitumor Short Hairpin RNA of Indoleamine 2,3- Dioxygenase." International Journal of Molecular Sciences 21, no. 18 (September 13, 2020): 6703. http://dx.doi.org/10.3390/ijms21186703.

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RNA-based therapeutics are considered as novel treatments for human diseases. Our previous study demonstrated that treatment with short-hairpin RNA against Ido1 (IDO shRNA) suppresses tumor growth, detects Th1-bias immune responses, and elevates expression of tryptophan transfer RNA (tRNATrp) in total splenocytes. In addition, depletion of Ly6g+ neutrophils attenuates the effect of IDO shRNA. The aim of this study was to investigate the regulatory network and the expression profile of tRNAs and other non-coding RNAs in IDO shRNA-treated spleens. The total splenocytes and magnetic bead-enriched splenic neutrophils were collected from the lung tumor bearing mice, which were treated with IDO shRNA or scramble IDO shRNA, and the collected cells were subsequently subjected to RNA sequencing. The gene ontology analysis revealed the different enrichment pathways in total splenocytes and splenic neutrophils. Furthermore, the expression of tRNA genes was identified and validated. Six isoacceptors of tRNA, with different expression patterns between total splenocytes and splenic neutrophils, were observed. In summary, our findings not only revealed novel biological processes in IDO shRNA-treated total splenocytes and splenic neutrophils, but the identified tRNAs and other non-coding RNAs may contribute to developing a novel biomarker gene set for evaluating the clinical efficiency of RNA-based cancer immunotherapies.
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Unwalla, Hoshang J., Hai-Tang Li, Ingrid Bahner, Ming-Jie Li, Donald Kohn, and John J. Rossi. "Novel Pol II Fusion Promoter Directs Human Immunodeficiency Virus Type 1-Inducible Coexpression of a Short Hairpin RNA and Protein." Journal of Virology 80, no. 4 (February 15, 2006): 1863–73. http://dx.doi.org/10.1128/jvi.80.4.1863-1873.2006.

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ABSTRACT We demonstrate a novel approach for coexpression of a short hairpin RNA (shRNA) with an open reading frame which exploits transcriptional read-through of a minimal polyadenylation signal from a Pol II promoter. We first observed efficient inducible expression of enhanced green fluorescent protein along with an anti-rev shRNA. We took advantage of this observation to test coexpression of the transdominant negative mutant (humanized) of human immunodeficiency type 1 (HIV-1) Rev (huRevM10) along with an anti-rev shRNA via an HIV-1-inducible fusion promoter. The coexpression of the shRNA and transdominant protein resulted in potent, long-term inhibition of HIV-1 gene expression and suppression of shRNA-resistant mutants. This dual expression system has broad-based potential for other shRNA applications, such as cases where simultaneous knockdown of mutant and wild-type transcripts must be accompanied by replacement of the wild-type protein.
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Dissertations / Theses on the topic "Shona novels"

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Mitchell, Andrea Michelle. "Ngozi : a novel." Thesis, University of Canterbury. School of Humanities, 2009. http://hdl.handle.net/10092/4450.

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Living as a white Zimbabwean in the 1990s meant a near-perfect life: your clothes were always clean and ironed, there was always tea in the silver teapot, gins and tonics were served on the verandah, and, in theory at least, black and white lived in harmony. As Mugabe’s presidency turned sour, however, this idyllic and privileged world began to crumble into anarchy. My family and I left to escape the political violence in 2002, and moved to New Zealand. My novel Ngozi draws on these experiences to tell the story of one troubled white family who struggle to stay afloat in the collapsing economy and escalating horror of Mugabe’s Zimbabwe. The story is told through the eyes of a young white girl, who is partly based on myself. When the farm invasions begin, the violence threatens to destroy the family’s way of life forever. They eventually leave Zimbabwe, but escaping the vengeful ghosts (‘ngozi’) of their past still seems impossible.
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Brightwell, Sara. "Identifying novel regulators of reprogramming using RNA interference." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/16156.

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Since Yamanaka and Takahashi first described the isolation of induced pluripotent stem cells (iPSCs) in 2006, researchers have invested a vast amount of time and resources into trying to understand the process of reprogramming. However, the exact mechanisms underlying the induction of somatic cells to pluripotency is still incompletely understood. With this in mind, a screening approach was undertaken to identify shRNA that enhance the reprogramming process. A retrovirus based system was used to knock down candidate genes during reprogramming of mouse embryonic fibroblasts (MEF) containing doxycycline-inducible reprogramming factors and a Nanog-GFP reporter, which is activated when cells become iPSCs. The initial round of screening with over 150 shRNA vectors successfully identified several shRNAs that enhance reprogramming. One of these shRNA vectors exhibited both faster reprogramming kinetics as determined by activation of the Nanog-GFP reporter 2 to 3 days earlier and increased reprogramming efficiency giving rise to >5 fold more GFP+ colonies when compared with a control. Cell surface marker analysis with flow cytometry demonstrated that changes in CD44 and ICAM1 expression, which occur preceding Nanog-GFP expression, were also accelerated. Validation of this shRNA determined that the enhanced reprogramming phenotype is the result of an unknown off-target effect. Microarray and RNA-sequencing analysis was carried out to identify the off target gene with a view to investigate the functional importance of this knock down and its role in establishing the pluripotency transcriptional network during reprogramming.
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Evans, Matthew C. "Quantitative Analysis of Novel Chemical and shRNA Based Methods to Increase Survival of Motor Neuron Protein Levels." eScholarship@UMMS, 2011. https://escholarship.umassmed.edu/gsbs_diss/566.

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Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder that is the leading genetic cause of infantile death. SMA is caused by homozygous deletion or mutation of the survival of motor neuron 1 gene (SMN1). The SMN2 gene is nearly identical to SMN1, however is alternatively spliced. The close relationship to SMN1 results in SMN2 being a very power genetic modifier of SMA disease severity and a target for therapies. In this study we attempt to characterize novel chemical compounds identified as potential activators of the SMN2 gene. Additionally, we sought to determine the regulatory role individual HDAC proteins use to control expression of full length protein from the SMN2 gene. We used quantitative PCR to determine the effects of novel compounds and shRNA silencing of individual HDACs on the steady state levels of a SMN2-luciferase reporter transcripts. We determined that the compounds identified in multiple reporter high throughput screens increased SMN protein levels via transcriptional activation of the SMN2 gene. Other compounds identified in the same screen functioned post-transcriptionally, possibly stabilizing the SMN protein itself by decreasing degradation. Furthermore, we determined that reduction of individual HDAC proteins was sufficient to increase SMN protein levels in a transgenic reporter system. Knockdown of class I HDAC proteins preferentially activated the reporter by increased promoter transcription. Silencing of class II HDAC proteins maintained transcriptional activity; however silencing of HDAC 5 and 6 also appeared to enhance inclusion of an alternatively spliced exon. This collective work defines a quantitative RNA based protocol to determine mechanism of SMN reporter increase in response to any chosen treatment method. Additionally, this work highlights HDAC proteins 2 and 6 as excellent investigative targets. These data are important to the basic understanding of SMN expression regulation and the refinements of current therapeutic compounds as well as the development of novel SMA therapeutics.
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Kim, Yun Cheol. "Novel strategies for studying gene and protein function random shRNA library synthesis and trasnposon directed base-exchange mutagenesis /." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1693038461&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Miller, Tyler Eugene. "Identifying Novel In Vivo Epigenetic Dependencies in Glioblastoma." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1464856610.

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Zigara, Herbert. "Gender bias in selected Shona novels." Diss., 2016. http://hdl.handle.net/10500/22168.

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This study sought to uncover gender bias in selected Shona novels and examine the manner in which authors present the subject. The major objectives were to identify the effects of hostile gender relations and assess Shona novel authors’ commitments to promote healthy gender relations which are pre-requisites for national development. The study adopted the dual approach by fusing feminism with Afrocentricity as the literary tool of analysis. These theories served as lenses for exploring gender biases in selected Shona novels. The liberal feminism was the most relevant feminist theory to this study because it advocates more about inclusion and unrestricted participation of women in all spheres of social life. The research was anchored on the qualitative design. The methodology used to gather data for analysis involved interviewing three out of four authors of this research’s selected Shona novels, eight Shona literature lecturers from teachers’ colleges and universities in Zimbabwe as well as five accomplished scholars who have also written their own Shona novels. Questionnaires were administered to thirty two students, twenty from teachers’ colleges and twelve from universities in Zimbabwe. The total number of all participants in this study was forty-eight and purposive sampling was used to come up with the sample. Data was analysed in descriptive form. This study has established that most Shona novelists are not gender neutral. While some authors are championing the emancipation of women others are perpetuating their marginalisation. Basing on the findings of this study, the researcher recommends that Shona authors should be sensitised through workshops, seminars or conferences on the need to pen gender balanced novels if national development is to be realised. This would help the societies who are the consumers of such novels to be gender neutral through emulating the positive portrayal attributed to characters. The Zimbabwe Schools Examinations Council (ZIMSEC), teachers’ colleges and universities should approve gender neutral Shona novels so that students can have appropriate role models to emulate. It is envisaged that this research will be of great benefit to all those who will have the privilege to access it. Gained knowledge will help to extricate women from marginalisation and also promote healthy gender relations.
African Languages
M.A. (African Languages)
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Nenduva, Aphios. "Investigating moral perversion in post-Independence Shona detective novels." Thesis, 2018. http://uir.unisa.ac.za/handle/10500/25689.

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The study unravels moral perversion in selected post-independence detective Shona novels. Moral perversion is a multi-faceted concept and the study focuses on corruption, sexual harassment, abuse of office, stealing, poaching and illegal manufacturing of intoxicating products as the key definers of moral perversion. Afrocentricity merged with Kawaida philosophy are the lenses used to pass critical judgements on the extent the selected literary practitioners portrayed literature rooted in the African ontological existence on moral perversion. Fictional works used as primary sources are Sajeni Chimedza (1984), Mutikitivha Dumbuzenene (1991), Munzwa mundove (1999) and Dandemutande, (1998). All the novels are set in the post-independence era in Zimbabwe when moral perversion is rife. The study is qualitative in nature and data was gathered using questionnaires and interviews from literary critics, publishers and novelists. Particular attention is paid on the causes of moral perversion, images of people in leadership positions and the implications of character assassination of leaders in relation to the development of purposeful literature. The study contends that moral insanity is an acknowledged problem in the post-independence era and novelists are portraying leaders as the chief culprits manning factionalism and unorthodox ways of acquiring resources at the expense of the majority of citizenry. Guided and informed by Afrocentricity, the study argues that novelists are raising pertinent issues although their views are myopic, simplistic and self-defeating because they are failing to see that the leaders are also victims who are victimizing other victims. Blaming the leadership on moral perversion ignoring the impact of colonialism, and neo-colonialism in shaping African personality creates more harm than good as this exonerates the imperialistic system of exploitation which impinges on African culture and personality. Therefore, the study argues that novelists erroneously blame individuals for the sins of a system. There is need to interrogate both external and internal factors to establish sustainable home-grown problem solving solutions to improve human condition and the development of functional literature in Africa.
African Languages
D. Litt. et Phil. (African Languages)
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Mapara, Jacob. "The Bible and literature: a case of biblical influence in some Shona novels." Diss., 2003. http://hdl.handle.net/10500/1235.

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A lot has been written on the development of the Shona novel and the influence of orature on it. This research while acknowledging the importance of such an observation makes yet another one. This other view is that there is also another element that has had a significant impact on the development and growth of the Shona novel. This research has endeavoured to highlight that the Shona novel is a product of the society where it is found which is influenced by The Bible. The novelists Chakaipa, Chidzero, Makari, Musengezi, Tsodzo, Zvarevashe and Ngugi wa Thiong'o's A Grain of Wheat which has been translated into Shona as Tsanga Yembeu have used The Bible as the backbone of their novels. Although these novelists have all used The Bible they have not used it in the same way and for the same purpose. They have used The Bible to justify the themes embedded in their works. This research at the end shows that it is difficult to label a literary product as either a success or a failure.
African Languages
M.A. (African Languages)
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Wasosa, Wellington. "Deviance and moralisiation as portrayed in selected post-independence Shona novels and short stories." Thesis, 2014. http://hdl.handle.net/10500/19842.

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This thesis is an exegesis of the portrayal of deviance in selected post-independence Shona fictional works. The analysis is done within the context of moralisation in Shona literature. The forms of deviant behaviour discussed include prostitution, homosexuality, crime and violence and negligence of duty within families. The fictional works are Mapenzi (1999), Totanga Patsva (2003), Ndozviudza Aniko? (2006), Ndafa Here? (2008), and Makaitei? (2008). All the fictional works are set during the period of the Zimbabwe Crisis and this becomes the context of the criticism of the manner in which deviance is handled by the writers. Particular attention is paid on the causes and solutions to deviance, images of deviants and the implications of such images in attempting to understand the realities of deviant behaviour. The research adopts an eclectic approach through a combination of literary and sociological theories to unpack issues concerning the litigious subject of deviance. The research fully acknowledges that deviance is a fluid and controversial concept as it varies with cultural frameworks and historical periods of certain societies. Thus the research has endeavoured to locate deviance with the ambit of Shona existential philosophy and the period of the Zimbabwe crisis. The research advances the argument that no human being is inherently deviant but there are certain circumstances and eventualities that are responsible for the development of such a personality. Therefore deviance herein is viewed as a response to the situation and in the case of this research it is the crisis which then is responsible for nurturing the people into deviance. In most of the situations, deviance is shown to be essentially a survival strategy by those who engage in it. Prostitution, homosexuality and crime have been shown to be largely economic necessities as the collapsing economy during the period of the crisis came with amorphous challenges and people resorted to anti-social behaviour in an attempt to live contenting lives. With regards to prostitution, homosexuality and crime, the writers have to a larger extent been able to contextualise deviance in terms of the crisis although Mabasa has been shown to display some ambivalence in his treatment of prostitutes in Mapenzi and Ndafa Here? There are instances he castigates prostitutes as social renegades which somehow weakens his vision. Apart from this, it has also been argued that deviant behaviour can be a result of the frustrations people face as they battle the vagaries of life. Violence and negligence of duty within families is argued to be a consequence of the frustrations from the poverty brought by the crisis and the movement into the diaspora as this has its own challenges that disempower people to carry out their duties as sanctioned by culture. Also, the research advances the argument that oral literature continues to impact on written literature and one such area is that of moralisation which continues to be a major priority of the writers. Except for the authors of the short stories in Totanga Patsva, moralisation on issues to do with deviance has been done in an enlightening way as the writers unearth the underlying causes of deviant behaviour and these are found in society and not individuals. The writers of the short stories have shown to be largely influenced by feminism and erroneously blame male deviants for the problems faced by women instead of explaining men`s behaviour in the context colonialism and neo-colonialism which brought various challenges related to gender relations in Africa not experienced hitherto. The direction in terms of qualitative development which Shona literature is taking in post-independence era is positive as the writers are shown to be tackling sensitive political, social and economic issues and their impact on the human condition.
African Languages
D. Litt. et Phil.
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Viriri, Eunitah. "The promotion of unhu in Zimbabwean secondary schools through the teaching of Shona literature : Masvingo urban district, a case study." Thesis, 2017. http://hdl.handle.net/10500/23737.

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This study examines the extent to which the teaching of Shona novels can be used to promote unhu (humanness) in Zimbabwean secondary schools where there has been a call for the teaching of cultural values. The school syllabi for Shona make this position abundantly clear. For that reason, anchoring the discussion on the role of literature in Africa as expounded by African scholars such as Ngugi wa Thiong’o (1981), p’Bitek (1986) and Achebe (1989) among others, the study observes that literature plays an important role in moulding character through advancing unhu. For instance, as Achebe (1989) argues that the novelist is a teacher, the study therefore locates literature as a life-affirming and life-extending affair. The discussion of the role of literature as a potential conduit for expressing unhu takes place within the theoretical confines of Afrocentricity, an African-centred theory that places the interests of Africa at the centre of any analysis involving African people. The selected novels namely Pfumo Reropa (1961), Kunyarara Hakusi Kutaura? (1983) and Ndafa Here? (2007) are therefore interrogated from an Afrocentric point of view. The three novels are representative of different historical epochs in Zimbabwe’s cultural trajectory. In addition, they have featured quite prominently on the school syllabi for Shona. Through a combination of interviews and critical analysis of the novels, the study crucially observes that the proper teaching of literature can effectively transform the thinking of learners thereby locating them in their own cultural platforms. However, for this to happen, teachers must be properly trained in order that they develop an appreciation of the value of literature in imparting unhu among learners. As a result, the study thus proposes sufficient conscientisation of teachers and learners on the concept and practice of unhu be systematically carried out. At the same, there is need for greater planning in constructing a more informing syllabus, as well as the deliberate inclusion of texts that canonise unhu.
African Languages
D. Litt. et Phil. (African Languages)
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Books on the topic "Shona novels"

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Aspects of the Shona novel and other related genres. Gweru [Zimbabwe]: Mambo Press, 1986.

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Shakugan no Shana. San Francisco, CA: VIZ Media, 2007.

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Chiwome, Emmanuel. A social history of the Shona novel. [Kadoma] Zimbabwe: Juta Zimbabwe (Pvt), 1996.

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Chiwome, Emmanuel. A social history of the Shona novel. Gweru, Zimbabwe: Mambo Press, 2002.

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Kahari, George P. The rise of the Shona novel: A study in development, 1890-1984. Gweru [Zimbabwe]: Mambo, 1990.

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Christopher, North, ed. GTO: the early years: The "pure love" gang of Shonan beach = Shonan junai gumi. Hamburg: Tokyopop, 2006.

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Takahashi, Yashichiro. Shakugan no Shana: The girl with fire in her eyes. San Francisco, Calif: VIZ Media, 2002.

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Fujisawa, Tohru. GTO, Great Teacher Onizuka: 14 days in Shonan. New York: Vertical, 2012.

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Showa 1953–1989: A History of Japan. Montreal, Canada: Drawn & Quarterly, 2015.

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Showa 1926–1939: A History of Japan. Montreal, Canada: Drawn & Quarterly, 2013.

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Book chapters on the topic "Shona novels"

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Taber, Douglass. "Synthesis of Heteroaromatics." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0066.

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Yasutaka Ishii of Kansai University has developed (J. Org. Chem. 2007, 72, 8820) a novel route to furans, using a mixed-metal catalyst to effect condensation of an aldehyde or 1,3 diketone such as 1 with an acceptor such as 2 to give the 3-furoate 3. In a complementary approach, Yong-Min Liang of Lanzhou University has found (J. Org. Chem. 2007, 72, 10276) that diazoacetate 5 will condense with an alkynyl ketone to give the 2-furoate 6. David W. Knight of Cardiff University has shown (Tetrahedron Lett. 2007, 48, 7709) that an alkynyl diol such as 7, readily available by dihydroxylation of the corrresponding alkenyl alkyne, cyclized to the furan on exposure to AgNO3 on silica gel. Professor Knight has also (Tetrahedron Lett. 2007, 48, 7906) established a route to poly-substituted pyrroles 10, by iodination of alkynyl sulfonamides such as 9. Similarly, Richard C. Larock of Iowa State University found (J. Org. Chem. 2007, 72, 9643) that I-Cl cyclized methoximes such as 11 to the corresponding iodo isoxazole 12, and Stephen L. Buchwald of MIT uncovered (Organic Lett. 2007, 9, 5521) the cyclization of an enamide such as 13 with I2 to the corresponding oxazole 14. In developing a more efficient route to a new class of materials that he has named “triazolamers”, Paramjit S. Arora of New York University was able (J. Org. Chem. 2007, 72, 7963) to effect diazo transfer to the amine 15 and subsequent condensation with 16 to give 17, without isolation of the intermediate azide. C. V. Asokan and E. R. Anabha of Mahatma Gandhi University have described (Tetrahedron Lett. 2007, 48, 5641) the activation of a ketone 18 followed by condensation with malononitrile 19 to give the pyridine 20. Hans-Ulrich Reissig of the Freie Universität Berlin has established (Organic Lett. 2007, 9, 5541) a complementary three-component coupling of a nitrile 21 with the allenyl anion 22, followed by a carboxylic acid 23 to deliver the pyridine 24. Akio Saito and Yuji Hanzawa of the Showa Pharmaceutical University have reported (Tetrahedron Lett. 2007, 48, 6852) the intramolecular Rh-catalyzed cyclization of a methoxime lactone such as 25 to the pyridine 26.
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Conference papers on the topic "Shona novels"

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Stoletov, Konstantin, David Bond, Hon Sing Leong, Emma Woolner, Srijan Raha, Amy Robertson, Francis Wong, Andries Zijlstra, and John D. Lewis. "Abstract 4972: In vivo whole genome shRNA screen reveals novel targets to block cancer metastasis." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4972.

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Li, Jie, Shan Zhu, David Kozono, Diahnn Futulan, David Gonda, Deepa Kushwaha, Kristopher Kahle, Stephen Elledge, and Clark C. Chen. "Abstract 4366: ShRNA-based cellular proliferation signaling analysis revealed DRD2 as a novel therapeutic target for glioblastoma." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4366.

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Patel, Ami, and Nancy Ratner. "Abstract 877: Identification of novel genes critical to survival of MPNST cells via medium throughput screening using lentiviral shRNA." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-877.

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Clarke, Christine A., Clarence M. Lee, Ibrahim Laniyan, and Paulette Furbert-Harris. "Abstract A83: Lentiviral shRNA-mediated knockdown of eosinophilic Galectin-10/Charcot-Leyden crystals: A novel approach to cancer immunotherapy." In Abstracts: Seventh AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; November 9-12, 2014; San Antonio, TX. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7755.disp14-a83.

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Zwang, Yaara, Casandra Chen, The Broad Institute Genomic Perturbation Platform, and William C. Hahn. "Abstract C73: A drug-modifier whole-genome shRNA screen identifies novel synthetic lethal interactions with PI3K inhibition in breast cancer." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; November 5-9, 2015; Boston, MA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1535-7163.targ-15-c73.

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Garcia, Felix Sanchez, Patricia Villagrasa, Junji Matsui, Bo-Juen Chen, Dylan Kotliar, Veronica Castro, Jose M. Silva, and Dana Pe'er. "Abstract 3168: Helios identifies novel oncogenes in breast cancer by integrating genomic characterization of primary tumors and functional shRNA-screens." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3168.

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Simpson, Craig D., Rose Hurren, Neil MacLean, Yanina Eberhard, Troy Ketela, Jason Moffat, and Aaron D. Schimmer. "Abstract A22: A genome-wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 12-16, 2011; San Francisco, CA. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1535-7163.targ-11-a22.

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Mimura, Hitoshi, Shunsuke Susa, Yoshiyuki Ito, Yasuo Saito, and Minoru Matsukura. "Adsorption Properties of Sr(II) on Zeolite Type Adsorbents and Their Irradiation Stabilities." In 2014 22nd International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icone22-30329.

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Abstract:
Radioactive waste treatment is planned in LWTF (Low-level radioactive Waste Treatment Facility, JAEA) for LLW generated from the Tokai-reprocessing facility. The target LLW consists of highly concentrated sodium nitrate (5 M NaNO3) containing low-level 90Sr. In this study, selective adsorption properties of Sr2+ for highly functional A type zeolites (A51-JHP, A51-J (Union Showa) and A-4, X type zeolite (F-9) and Titanic acid-PAN (polyacrylamide) were clarified by batch and column adsorption methods. The irradiation stabilities of these adsorbents were also evaluated. The distribution properties of Sr2+ on different adsorbents were compared in simulated waste solution (5 M NaNO3, 0.1 ppm Sr2+, 85Sr as tracer). The order of distribution coefficients (Kd,Sr) was Titanic acid-PAN > A51-JHP > A51-J > A-4 > F-9. The largest value of Kd,Sr for titanic acid-PAN was estimated to be 218 cm3/g, while the saturated capacity (Qmax) was very small. Titanic acid-PAN had also the largest uptake rate of Sr2+ ions and the uptake attained equilibrium within 8 h. On the other hand, A51-JHP had a relatively large Kd,Sr value above 100 cm3/g and a Qmax value of 0.65 mmol/g. The breakthrough properties of Sr2+ were examined by varying cations present (single and mixed solutions) and flow rate (0.08 and 0.17 cm3/min). The components for the single solution were 400 g/L NaNO3, 100 ppm Sr2+, 85Sr as tracer, and the mixed solution contains 200 ppm Cs+, 100 ppm Ca2+, 50 ppm Mg2+, 50 ppm RuNO3+ in addition to the single solution components. The breakthrough curve for Titanic acid-PAN column using single solution had an S-shaped profile, while the “concentration phenomenon” exceeding C/C0 (breakthrough ratio) = 1 was observed in the case of mixed solution. As for the A51-JHP column, the breakthrough curve for single solution was similar to that for mixed solution and the 5% breakpoint was enhanced by decreasing the flow rate. The A51-JHP was stable under 60Co-irradiation up to 2.54 MGy; Kd,Sr and Qmax values were almost constant. In contrast, Titanic acid-PAN was affected above 0.28 MGy, due to the radiolysis of PAN matrix, and this surface alteration led to the release of active component of titanic acid. The novel A type zeolite (A51-JHP) is thus expected for the selective removal of Sr2+ in LWTF. The optimization of particle size and flow rate should be examined before practical use.
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Reports on the topic "Shona novels"

1

Corcoran, Ryan B. An In Vivo shRNA-Drug Screen to Identify Novel Targeted Therapy Combinations for KRAS Mutant Cancers. Fort Belvoir, VA: Defense Technical Information Center, September 2013. http://dx.doi.org/10.21236/ada610560.

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Corcoran, Ryan B. An in Vivo shRNA-Drug Screen to Identify Novel Targeted Therapy Combinations for KRAS Mutant Cancers. Fort Belvoir, VA: Defense Technical Information Center, December 2014. http://dx.doi.org/10.21236/ada620992.

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