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1

Lacout, A., M. El Hajjam, A. Khalil, P. Lacombe, and P. Y. Marcy. "Shunt systémo-pulmonaire rétrograde simulant une embolie pulmonaire." Journal de Radiologie Diagnostique et Interventionnelle 94, no. 3 (2013): 345–50. http://dx.doi.org/10.1016/j.jradio.2012.06.008.

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2

Deroux, A., E. Chidlovskii, C. Pison, L. Bouillet, and P. Couturier. "Effet shunt gazométrique et hypoxémie réfractaire en l’absence d’embolie pulmonaire." La Revue de Médecine Interne 32 (December 2011): S326. http://dx.doi.org/10.1016/j.revmed.2011.10.041.

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3

Mikail, N., C. Heimburger, N. Messas, et al. "Insuffisance cardiaque à débit élèvé par shunt intraosseux : apport de la scintigraphie pulmonaire aux macroagrégats d’albumine marqués." Médecine Nucléaire 36, no. 4 (2012): 208. http://dx.doi.org/10.1016/j.mednuc.2012.02.016.

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4

Gaborit, B., M. Lefebvre, M. Lecouffe, et al. "Syndrome hépatopulmonaire aggravé par un shunt droit-gauche entre une varice oesophagienne et une veine pulmonaire inférieure." La Revue de Médecine Interne 32 (June 2011): S189—S190. http://dx.doi.org/10.1016/j.revmed.2011.03.328.

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5

DING, JINLI, YOUJUN LIU, LINJUAN CHAI, XUE CAO, and FENG WANG. "COMPUTATIONAL FLUID DYNAMICS OF TWO PATIENT-SPECIFIC SYSTEMIC TO PULMONARY SHUNTS." Journal of Mechanics in Medicine and Biology 13, no. 01 (2013): 1350005. http://dx.doi.org/10.1142/s021951941350005x.

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Tetralogy of Fallot is the most common cyanotic congenital heart defect. For severe cases, inserting a systemic to pulmonary shunt, which distributes part of systemic artery blood into the pulmonary artery, is the preferable palliative surgery. Based on the computed tomography images and three-dimensional geometry technologies, two patient-specific anatomical options of systemic to pulmonary shunts including the aorta to pulmonary shunt (APS) and innominate artery to pulmonary shunt (IPS) have been simulated for computational fluid dynamics. The objective of this study was to predict the hemod
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6

Nguyen, S., S. Leroy, N. Bautin, et al. "Fibrose pulmonaire idiopathique et shunt droit-gauche par foramen ovale perméable : amélioration clinique et gazométrique après fermeture percutanée." Revue des Maladies Respiratoires 24, no. 5 (2007): 631–34. http://dx.doi.org/10.1016/s0761-8425(07)91132-8.

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7

Agematsu, Kota, Toru Okamura, Yoji Takiguchi, Fumiya Yoneyama, and Yorikazu Harada. "Rapid growth of pulmonary artery after intrapulmonary artery septation." Asian Cardiovascular and Thoracic Annals 26, no. 6 (2018): 479–81. http://dx.doi.org/10.1177/0218492318782821.

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Intrapulmonary artery septation is employed in patients with unbalanced pulmonary artery growth. A baby girl received a systemic pulmonary shunt in the neonatal period and bilateral Glenn shunts in early infancy. Once the Glenn shunts were established, the right pulmonary artery became hypoplastic. We performed intrapulmonary artery septation involving the Glenn shunts to the left pulmonary artery and the systemic pulmonary shunt to the right pulmonary artery. As early as 3 months after intrapulmonary artery septation, right pulmonary artery growth was observed. Eventually, Fontan circulation
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8

WILMSHURST, Peter, and Simon NIGHTINGALE. "Relationship between migraine and cardiac and pulmonary right-to-left shunts." Clinical Science 100, no. 2 (2001): 215–20. http://dx.doi.org/10.1042/cs1000215.

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A relationship between migraine with aura and the presence of right-to-left shunts has been reported in two studies. Right-to-left shunts are also associated with some forms of decompression illness. While conducting research in divers with decompression illness, it was our impression that divers with a large shunt often had a history of migraine with aura in everyday life and after dives. Therefore we routinely asked all divers about migraine symptoms. The medical records of the last 200 individuals referred for investigation of decompression illness were reviewed to determine the association
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9

Motz, Reinald, Armin Wessel, Wofgang Ruschewski, and Jochen Bürsch. "Reduced frequency of occlusion of aorto-pulmonary shunts in infants receiving Aspirin." Cardiology in the Young 9, no. 5 (1999): 474–77. http://dx.doi.org/10.1017/s1047951100005370.

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AbstractObjectiveInfants with severely reduced pulmonary perfusion due to complex congenital cardiac malformations are in need of an improved flow of blood to the lungs. One option for treatment is to construct a systemic-to-pulmonary arterial shunt. Although such shunts have been used since 1945, their spontaneous occlusion remains a major problem in the long-term.DesignWe studied all infants in whom a systemic-to-pulmonary arterial shunt had been constructed using a Gore-Tex tube graft between December 1989 and March 1996.PatientsOf 46 infants undergoing construction of a shunt, 7 (15°) died
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10

Wacker, Julie, and Maurice Beghetti. "Shunts: When to Close Them and When to Create Them for Palliation." Advances in Pulmonary Hypertension 19, no. 1 (2020): 16–20. http://dx.doi.org/10.21693/1933-088x-19.1.16.

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Pulmonary hypertension, despite specific therapies, remains an incurable disease with a dreadful prognosis. A systemic-to-pulmonary shunt, if left unrepaired, can cause pulmonary arterial hypertension. With time, pulmonary vascular disease develops, and closure of the shunt becomes contraindicated. Operability criteria are not well defined and rely mainly on hemodynamic values that fail to predict long-term survival. Shunts can also be created in selected cases of advanced pulmonary hyper-tension, in view of off-loading the right ventricle and improving cardiac output at the cost of cyanosis.
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11

Johnson, Rebecca C., Sanjeev A. Datar, Peter E. Oishi, et al. "Adaptive right ventricular performance in response to acutely increased afterload in a lamb model of congenital heart disease: evidence for enhanced Anrep effect." American Journal of Physiology-Heart and Circulatory Physiology 306, no. 8 (2014): H1222—H1230. http://dx.doi.org/10.1152/ajpheart.01018.2013.

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Patients with pulmonary hypertension associated with congenital heart disease survive longer with preserved right ventricular (RV) function compared with those with primary pulmonary hypertension. The purpose of this study was to test the hypothesis that superior RV performance can be demonstrated, at baseline and when challenged with increased RV afterload, in lambs with chronic left-to-right cardiac shunts compared with control lambs. A shunt was placed between the pulmonary artery and the aorta in fetal lambs (shunt). RV pressure-volume loops were obtained 4 wk after delivery in shunt and c
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12

Homma, Yukako, and Yasunobu Hayabuchi. "Successful treatment by stent implantation for systemic-to-pulmonary shunt obstruction due to a Staphylococcus aureus abscess: a case report." Cardiology in the Young 30, no. 10 (2020): 1538–40. http://dx.doi.org/10.1017/s1047951120002565.

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AbstractA 13-year-old girl with a single ventricle and bilateral systemic-to-pulmonary shunts developed hypoxia due to shunt stenosis, which was caused by a methicillin-sensitive Staphylococcus aureus abscess. Stent implantation associated with appropriate antibiotic administration was crucial to dilate and maintain shunt patency.
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13

Krasemann, Thomas, Aphrodite Tzifa, Eric Rosenthal, and Shakeel A. Qureshi. "Stenting of modified and classical Blalock–Taussig shunts – lessons learned from seven consecutive cases." Cardiology in the Young 21, no. 4 (2011): 430–35. http://dx.doi.org/10.1017/s1047951111000254.

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AbstractIn neonates and infants with a shunt-dependent pulmonary circulation, stenosis of the shunt needs to be treated aggressively to prevent a fatal outcome. We report the technique and outcome in seven consecutive neonates and infants with Blalock–Taussig shunt stenosis, who were treated with intraluminal stents. Stenting of classical or modified Blalock–Taussig shunts is technically feasible and can be used as a rescue procedure. Neointimal dissection is less likely compared with balloon angioplasty of the shunt alone.
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14

Illner, Julia, Holger Reinecke, Helmut Baumgartner, and Gerrit Kaleschke. "Stenting of modified Blalock–Taussig shunt in adult with palliated pulmonary atresia and ventricular septal defect: a case report." European Heart Journal - Case Reports 3, no. 4 (2019): 1–4. http://dx.doi.org/10.1093/ehjcr/ytz201.

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Abstract Background Adults with complex congenital heart disease palliated with systemic-to-pulmonary artery shunts have become rare and represent a particularly challenging patient group for the cardiologist. One of the complications and causes of severe clinical deterioration during long-term follow-up are progressive obstruction or total occlusion of the shunt. The risk for surgical intervention is frequently high and catheter intervention may be complicated by complex anatomy and shunt calcification. Case summary We report the case of a 47-year-old man with uncorrected (palliated) pulmonar
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15

Day, Ronald W., Charles M. Baker, John R. Caton, John A. Hawkins, and Edwin C. McGough. "Bidirectional cavopulmonary shunt with an additional source of pulmonary flow: an interim or final stage of palliation." Cardiology in the Young 7, no. 1 (1997): 63–70. http://dx.doi.org/10.1017/s1047951100005886.

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AbstractA bidirectional cavopulmonary shunt is performed in patients with single ventricle physiology to improve or maintain systemic oxygenation while decreasing the workload of the heart. During a period of 10 years, bidirectional cavopulmonary shunts were performed in 50 patients at our institution. The procedure was performed with an additional source of pulmonary flow through the pulmonary valve or a systemic to pulmonary shunt in 27 patients and without an additional source of pulmonary flow in 23 patients. Preoperative and postoperative chest radiographs, pulmonary angiograms, oxygenati
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16

Elhammady, Mohamed Samy A., David M. Benglis, Sanjiv Bhatia, David I. Sandberg, and John Ragheb. "Ventriculoatrial shunt catheter displacement in a child with partial anomalous pulmonary venous return." Journal of Neurosurgery: Pediatrics 2, no. 1 (2008): 68–70. http://dx.doi.org/10.3171/ped/2008/2/7/068.

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Ventriculoatrial (VA) shunts remain the most used alternative to ventriculoperitoneal shunts in infants with hydrocephalus. The authors report a case of an acute VA shunt malfunction as a result of distal catheter displacement in an 18-month-old girl with partial anomalous pulmonary venous return. The child presented with respiratory compromise, and a chest radiograph revealed a lung infiltrate and normal position of the distal shunt catheter tip. Computed tomography demonstrated stable ventricle size in comparison with previous studies. As the patient's respiratory distress progressed, she re
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17

Sakaki, Shinichiro, Taiyu Hayashi, and Hiroshi Ono. "Pulmonary arteriovenous malformations in a patient with single ventricle and polysplenia syndrome." BMJ Case Reports 12, no. 7 (2019): e229491. http://dx.doi.org/10.1136/bcr-2019-229491.

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A 5-month-old girl with single ventricle, interrupted inferior vena cava and polysplenia syndrome palliated with bilateral Blalock-Taussig shunts developed severe cyanosis despite apparently increased pulmonary blood flow. Angiography revealed diffuse pulmonary arteriolar capillary dilatation and early pulmonary venous filling, suggesting the presence of pulmonary arteriovenous malformations. Abdominal angiography at 6 months demonstrated a large extrahepatic portosystemic shunt, which was percutaneously closed with a vascular plug. Kawashima operation was performed 2 weeks after portosystemic
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18

Kaestner, Michael, Ronald P. Handke, Joachim Photiadis, Matthias Sigler, and Martin B. E. Schneider. "Implantation of stents as an alternative to reoperation in neonates and infants with acute complications after surgical creation of a systemic-to-pulmonary arterial shunt." Cardiology in the Young 18, no. 2 (2008): 177–84. http://dx.doi.org/10.1017/s1047951108001959.

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AbstractCreation of a systemic-to-pulmonary shunt is still the firstline treatment in neonates with duct-dependent pulmonary circulation, or in patients with hypoplastic left heart syndrome as a part of the first stage of the Norwood sequence. Acute complications after such surgery, such as stenosis, thrombosis, or kinking, are potentially lifethreatening. These complications require immediate revision or exchange of the shunt. In this report, we discuss interventional treatment as an alternative to surgery in 5 patients with acute stenosis or complete occlusion of a shunt.The age of the patie
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19

Perera, Eranga, Shweta Bhatt, and Vikram S. Dogra. "Complications of Denver Shunt." Journal of Clinical Imaging Science 1 (January 8, 2011): 6. http://dx.doi.org/10.4103/2156-7514.75247.

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Hepatic hydrothorax secondary to transdiaphragmatic spread of peritoneal fluid can cause respiratory discomfort to the patient. Draining of hydrothorax helps relieve these symptoms. Pleurovenous shunt (Denver shunt) is a relatively non-invasive method of shunting the pleural fluid to the central venous system. Reported complications of pleurovenous shunts are shunt failure, pulmonary edema, post shunt coagulopathy, deep vein thrombosis, and infection. We report a rare case of a leak at the venous end of the catheter that was placed within the right internal jugular vein, resulting in a large c
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20

Overgaard, Johannes, Jonathan A. W. Stecyk, Anthony P. Farrell, and Tobias Wang. "Adrenergic control of the cardiovascular system in the turtleTrachemys scripta." Journal of Experimental Biology 205, no. 21 (2002): 3335–45. http://dx.doi.org/10.1242/jeb.205.21.3335.

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SUMMARYFreshwater turtles, Trachemys scripta, like all non-crocodilian reptiles, are able to shunt blood between the pulmonary and systemic circulations owing to their undivided ventricle. The prevailing hypothesis is that the ratio of pulmonary and systemic resistances is the primary determinant of cardiac shunting in turtles. In the present study, we have examined the adrenergic influences on vascular resistances in the pulmonary and systemic circulations and the associated effects on cardiac shunts in turtles. To achieve this objective, systemic blood flow and pressures and pulmonary blood
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21

Liu, Jiawei, Haiyun Yuan, Neichuan Zhang, et al. "3D Simulation Analysis of Central Shunt in Patient-Specific Hemodynamics: Effects of Varying Degree of Pulmonary Artery Stenosis and Shunt Diameters." Computational and Mathematical Methods in Medicine 2020 (February 14, 2020): 1–11. http://dx.doi.org/10.1155/2020/4720908.

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The objective of this study was to compare the effects of different shunt diameters and pulmonary artery (PA) stenosis grades on the hemodynamics of central shunts to determine an optimal surgical plan and improve the long-term outcomes of the operation. A 3D anatomical model was reconstructed based on the patient’s clinical CT data. 3D computational fluid dynamics models were built with varying degrees of stenosis (the stenosis ratio α was represented by the ratio of blood flow through the main pulmonary artery to cardiac output, ranging from 0 to 30%; the smaller the value of α, the more sev
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22

Kluge, Stefan, Hans Jörg Baumann, Jan Regelsberger, et al. "Pulmonary hypertension after ventriculoatrial shunt implantation." Journal of Neurosurgery 113, no. 6 (2010): 1279–83. http://dx.doi.org/10.3171/2010.6.jns091541.

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Object Ventriculoatrial (VA) shunts inserted for the treatment of hydrocephalus are known to be a risk factor for pulmonary hypertension. The aim of this study was to evaluate the incidence of pulmonary hypertension among adult patients with VA shunts. Methods All patients who had received a VA shunt at one of two institutions between 1985 and 2000 were invited for a cardiopulmonary evaluation. The investigation included a thorough history taking, clinical examination, echocardiography, and pulmonary function testing including diffusing capacity of the lung for carbon monoxide (DLCO). Pulmonar
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23

Choi, Connie, Kimberlee Gauvreau, Philip Levy, Ryan Callahan, Kathy J. Jenkins, and Minghui Chen. "Longer Exposure to Left-to-Right Shunts Is a Risk Factor for Pulmonary Vein Stenosis in Patients with Trisomy 21." Children 8, no. 1 (2021): 19. http://dx.doi.org/10.3390/children8010019.

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We conducted a study to determine whether patients born with Trisomy 21 and left-to-right shunts who develop pulmonary vein stenosis (PVS) have a longer exposure to shunt physiology compared to those who do not develop PVS. We included patients seen at Boston Children’s Hospital between 15 August 2006 and 31 August 2017 born with Trisomy 21 and left-to-right shunts who developed PVS within 24 months of age. We conducted a retrospective 3:1 matched case–control study. The primary predictor was length of exposure to shunt as defined as date of birth to the first echocardiogram showing mild or no
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Leopold, Cornelius, Jelena von Ohain, Cordula Wolf, et al. "Reasons for Failure of Systemic-to-Pulmonary Artery Shunts in Neonates." Thoracic and Cardiovascular Surgeon 67, no. 01 (2018): 002–7. http://dx.doi.org/10.1055/s-0037-1621706.

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Background Systemic-to-pulmonary artery shunt placement is an established palliative procedure for congenital heart disease. Although it is thought to be a simple operation, it is associated with significant morbidity and mortality. Methods Data for all neonates who underwent surgery for a systemic-to-pulmonary artery shunt between 2000 and 2016 were reviewed. The study endpoints were shunt failure and shunt-related mortality. Shunt failure was defined as a shunt dysfunction because of thrombosis or stenosis requiring intervention or reoperation; shunt mortality was defined as death because of
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25

Piggott, Kurt D., David G. Nykanen, and Susan Smith. "Computed Tomography Angiography Successfully Used to Diagnose Postoperative Systemic-Pulmonary Artery Shunt Narrowing." Case Reports in Cardiology 2011 (2011): 1–4. http://dx.doi.org/10.1155/2011/802643.

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In recent years, there has been a marked reduction in surgical mortality for many complex forms of congenital heart disease. Treatment or palliative strategies vary but may include systemic-pulmonary central or Blalock-Taussig shunt. These shunts can be complicated by overcirculation, infection, thrombosis, and thromboembolism. Many diagnostic modalities are available to aide in diagnosis of postoperative shunt complications including echocardiography and cardiac catheterization but these may be invasive, inconclusive, or difficult to obtain adequate images. Computed tomography angiography (CT
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26

Andreis, Alessandro, Gabriella Agnoletti, and Paolo Scacciatella. "Incidental diagnosis of four pulmonary arteriovenous fistulas during patent foramen ovale closure: a case report." Cardiology in the Young 30, no. 9 (2020): 1363–65. http://dx.doi.org/10.1017/s1047951120002152.

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AbstractCryptogenic cerebral ischemia in young patients is commonly ascribed to paradoxical embolism. We report the clinical case of a young patient with cryptogenic stroke and a patent foramen ovale, undergoing percutaneous closure of atrial septal defect. Contrast transoesophageal echocardiography at the end of the procedure demonstrated massive late residual right-to-left shunt, due to the coexistence of pulmonary arteriovenous fistulas that were subsequently closed. Routinary adoption of contrast transoesophageal echocardiography at the end of patent foramen ovale closure interventions may
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27

Wang, T., and J. W. Hicks. "The interaction of pulmonary ventilation and the right-left shunt on arterial oxygen levels." Journal of Experimental Biology 199, no. 10 (1996): 2121–29. http://dx.doi.org/10.1242/jeb.199.10.2121.

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In adult mammals, arterial blood gases closely reflect lung gas composition, and arterial blood gases can, therefore, be effectively regulated through changes in ventilation. This is not the case among most ectothermic vertebrates, where the systemic and pulmonary circulations are not completely separated, resulting in central vascular shunts. In the presence of a right-to-left shunt (R-L shunt), the O2 levels (PO2 and haemoglobin O2-saturation) of systemic arterial blood are depressed relative to those of the blood returning from the lungs. Arterial blood gas composition is, accordingly, not
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28

Arvind, Balaji, Jay Relan, and Shyam S. Kothari. "“Treat and repair” strategy for shunt lesions: a critical review." Pulmonary Circulation 10, no. 2 (2020): 204589402091788. http://dx.doi.org/10.1177/2045894020917885.

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The issue of operability in patients with shunt lesions and raised pulmonary vascular resistance is contentious. Several reports suggest that patients traditionally considered inoperable may be operated after treatment with targeted drug therapy for pulmonary arterial hypertension. We reviewed all the published literature of “treat and repair” approach to gain more insights into the utility of this approach. A critical appraisal of the published literature suggests that this approach is less established for patients with post tricuspid shunts, and for patients with pre-tricuspid shunts with mo
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29

Fujita, Shuhei, Masaaki Yamagishi, Yoshinobu Maeda, et al. "The effect of a valved small conduit on systemic ventricle–pulmonary artery shunt in the Norwood-type palliation." European Journal of Cardio-Thoracic Surgery 57, no. 6 (2020): 1105–12. http://dx.doi.org/10.1093/ejcts/ezz377.

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Abstract OBJECTIVES The aim of this study was to clarify the impact of valved systemic ventricle–pulmonary artery (SV–PA) shunt on outcomes after stage-1 Norwood-type palliation (NP) compared with the modified Blalock–Taussig shunt. METHODS Consecutive patients who underwent NP between 2003 and 2019 were enrolled. SV–PA shunts using the expanded polytetrafluoroethylene valved conduit were implanted in 18 patients (valved SV–PA group), and another 18 patients underwent modified Blalock–Taussig shunt during NP (modified Blalock–Taussig shunt group). All valved conduits were made in our instituti
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Ide, Yujiro, Hisateru Tachimori, Yasutaka Hirata, et al. "Risk analysis for patients with a functionally univentricular heart after systemic-to-pulmonary shunt placement." European Journal of Cardio-Thoracic Surgery 60, no. 2 (2021): 377–83. http://dx.doi.org/10.1093/ejcts/ezab077.

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Abstract OBJECTIVES To investigate risk factors for mortality after systemic-to-pulmonary (SP) shunt procedures in patients with a functionally univentricular heart using the Japan Cardiovascular Surgery Database registry. METHODS Clinical data from 75 domestic institutions were collected. Overall, 812 patients with a functionally univentricular heart who underwent initial SP shunt palliation were eligible for analysis. Patients with pulmonary atresia with an intact ventricular septum and patients with a SP shunt as part of the Norwood procedure were excluded. Risk factors for 30- and 90-day m
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Filaire, Laura, Aurelie Chalard, Hélène Perrault, et al. "Validation of intracardiac shunt using thoracic bioimpedance and inert gas rebreathing in adults before and after percutaneous closure of atrial septal defect in a cardiology research unit: study protocol." BMJ Open 9, no. 5 (2019): e024389. http://dx.doi.org/10.1136/bmjopen-2018-024389.

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IntroductionIntrathoracic shunt quantification is a major factor for appropriate clinical management of heart and pulmonary diseases. Intracardiac shunts quantified by pulmonary to systemic output ratio (Qp/Qs) are generally assessed by Doppler echocardiography, MRI or catheterisation. Recently, some authors have suggested the concomitant use of thoracic bioimpedance (TB) and inert gas rebreathing (IGR) techniques for shunt quantification. The purpose of this study is to validate the use of this approach under conditions where shunt fraction is directly quantified such as in patients with isol
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Hull, Dearbhla A., Elliot Shinebourne, Leon Gerlis, Andrew G. Nicholson, and Mary N. Sheppard. "Rupture of pulmonary aneurysms in association with long-standing Waterston shunts." Cardiology in the Young 11, no. 1 (2001): 123–27. http://dx.doi.org/10.1017/s1047951100012531.

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AbstractAnastomosis of the ascending aorta to the right pulmonary artery, the so-called Waterston shunt, was undertaken as a palliative procedure for children with cyanotic congenital heart disease due to obstruction of the pulmonary outflow tract with reduced pulmonary blood flow. We present the clinico-pathological correlations in two patients who underwent construction of Waterston shunts as neonates, and subsequently died of ruptured pulmonary aneurysms in adult life. Rupture should, therefore, be recognized as a late complication of this procedure, and be considered in the long-term follo
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Migliavacca, Francesco, Giancarlo Pennati, Gabriele Dubini, et al. "Modeling of the Norwood circulation: effects of shunt size, vascular resistances, and heart rate." American Journal of Physiology-Heart and Circulatory Physiology 280, no. 5 (2001): H2076—H2086. http://dx.doi.org/10.1152/ajpheart.2001.280.5.h2076.

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Hypoplastic left heart syndrome is the most common lethal cardiac malformation of the newborn. Its treatment , apart from heart transplantation , is the Norwood operation. The initial procedure for this staged repair consists of reconstructing a circulation where a single outlet from the heart provides systemic perfusion and an interpositioning shunt contributes blood flow to the lungs. To better understand this unique physiology, a computational model of the Norwood circulation was constructed on the basis of compartmental analysis. Influences of shunt diameter, systemic and pulmonary vascula
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Kraus, Carl, Vladimir Sheynzon, Robert Hanna, and Joshua Weintraub. "Single Stage Endovascular Treatment of a Type 2 Abernethy Malformation: Successful Nonsurgical Outcome in a Case Report." Case Reports in Radiology 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/491867.

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Abernethy malformations are a rare collection of congenital hepatic portosystemic shunts. Our 19-year-old patient is with a type 2 Abernethy malformation elected permanent shunt closure following worsening dyspnea. This report details a single stage endovascular technique wherein shunt closure was achieved immediately by placement of an aortic endograft. At 5-month follow-up, the patient reported decreased shortness of breath. Furthermore, ultrasound investigation demonstrated a patent portal vein and right heart catheterization 6 months after procedure revealed decreased pulmonary hypertensio
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35

Beaufort-Krol, Gertie C. M., Willem G. Zijlstra, Janny Takens, et al. "Lactate kinetics at rest and during exercise in lambs with aortopulmonary shunts." Journal of Applied Physiology 86, no. 3 (1999): 832–39. http://dx.doi.org/10.1152/jappl.1999.86.3.832.

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In a previous study [G. C. M. Beaufort-Krol, J. Takens, M. C. Molenkamp, G. B. Smid, J. J. Meuzelaar, W. G. Zijlstra, and J. R. G. Kuipers. Am. J. Physiol. 275 ( Heart Circ. Physiol. 44): H1503–H1512, 1998], a lower systemic O2 supply was found in lambs with aortopulmonary left-to-right shunts. To determine whether the lower systemic O2 supply results in increased anaerobic metabolism, we used [1-13C]lactate to investigate lactate kinetics in eight 7-wk-old lambs with shunts and eight control lambs, at rest and during moderate exercise [treadmill; 50% of peak O2consumption (V˙o 2)]. The mean l
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pennati, giancarlo, francesco migliavacca, francesca gervaso, and gabriele dubini. "assessment by computational and in vitro studies of the blood flow rate through modified blalock-taussig shunts." Cardiology in the Young 14, S3 (2004): 24–29. http://dx.doi.org/10.1017/s1047951104006511.

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surgical repairs of many severe congenital cardiac malformations, such as the procedures used to redirect the flow of blood in the setting of absent or suboptimal perfusions, are performed either using direct vascular anastomosis, or by the insertion of interpositioned prosthetic shunts. examples of these applications can be found when considering those cardiac malformations characterized by the common physiological feature of having a single pumping ventricle, usually due to the incomplete and rudimentary form of the complementary ventricle. in this situation, since the circulation depends on
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Hu, Antoinette, Saxena Saurab, Armando Salim Munoz Abraham, et al. "Successful Thoracoscopic Excision of Type 0 CPAM in a Newborn." Journal of Neonatal Surgery 8, no. 3 (2019): 25. http://dx.doi.org/10.47338/jns.v8.245.

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Thoracoscopic excision of a Type 0 congenital pulmonary airway malformations (CPAM) is rarely described in literature. A 1-day-old female neonate presented with prenatal diagnosis of right lung CPAM. Mother had undergone fetoscopic thoracoamniotic shunt placement which led to radiographic resolution of large CPAM cyst. Soon after delivery, the patient developed multiple premature ventricular contractions (PVCs) that were thought to be secondary to retained shunts. Thoracoscopic excision of CPAM performed.
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38

Harling, Solweig, Tomas Jansson, Milad El-Segaier, and Erkki Pesonen. "Quantification of left-to-right shunt through patent ductus arteriosus by colour Doppler in children admitted for a device closure." Cardiology in the Young 22, no. 1 (2011): 57–62. http://dx.doi.org/10.1017/s1047951111000916.

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AbstractPurposeOur animal model suggests that quantification of ductal flow from colour Doppler pixels is possible. We aimed to clarify whether this method can be used to determine a clinically significant ductal shunt in children.MethodsWe retrospectively quantified ductal flow from saved images from 20 children who had been admitted for device occlusion of patent ductus arteriosus. Colour Doppler images over the main stem of the pulmonary artery were obtained in longitudinal cross-sections. The colour pixel percentages during diastole, representing ductal flow, were correlated with the docum
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39

Ali, J., and K. Duke. "Does indomethacin affect shunt and its response to PEEP in oleic acid pulmonary edema?" Journal of Applied Physiology 62, no. 6 (1987): 2187–92. http://dx.doi.org/10.1152/jappl.1987.62.6.2187.

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We assessed hemodynamics, lobar perfusion, and shunts at base line 1.5 h after unilobar oleic acid edema, 15 min after indomethacin (10 mg/kg iv), and 15 min after positive end-expiratory pressure (PEEP) (10 cm) in 10 dogs. In 10 additional dogs (control) the same measurements were made but no indomethacin was administered. Shunts of the edematous lobe were: 10.6 +/- 6.3, 54.1 +/- 22.8, 30.8 +/- 16.6, and 12.4 +/- 6.3% for dogs administered indomethacin and 10.9 +/- 4.2, 53.8 +/- 13.1, 72.3 +/- 14.6, and 11.5 +/- 4.1% for the controls. Perfusions (% cardiac output) to the edematous lobe were 2
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40

Batlivala, Sarosh P., Mary K. Hood, Jannika Dodge-Khatami, et al. "Staged Palliation of Cyanotic Obstructive Lesions With a Modified Right Ventricular Outflow Procedure." World Journal for Pediatric and Congenital Heart Surgery 9, no. 1 (2018): 68–73. http://dx.doi.org/10.1177/2150135117738007.

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Background: Traditional palliation for biventricular cyanotic congenital heart lesions often involves staging with systemic-to-pulmonary arterial shunts to secure pulmonary blood flow (PBF) in the newborn period prior to complete repair. However, shunts may lead to life-threatening events secondary to shunt occlusion or acute coronary steal. They may be associated with morbidity secondary to diastolic runoff, systemic steal and volume loading, and do not provide pulsatile flow which has the potential to promote pulmonary artery (PA) growth. We have alternatively performed modified right ventri
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41

Sosdean, Raluca, Adina Ionac, Alina Stan, Sorin Pescariu, and Adrian Ursulescu. "Succesfull management of a giant pulmonary artery aneurysm associated with severe congenital pulmonary valve stenosis in an adult patient." Romanian Journal of Cardiology 30, no. 1 (2020): 78–83. http://dx.doi.org/10.47803/rjc.2020.30.1.78.

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Pulmonary artery aneurysms are rare entities usually associated with congenital anomalies that increase blood flow/pressure in the pulmonary circulation, like left to right shunts and/or severe pulmonary valve pathologies. Clear re-commendations about their management are lacking. We report on a case of severe congenital pulmonary valve stenosis associated with a giant pulmonary artery aneurysm, secondary right ventricular outflow tract obstruction and right to left atrial shunt. We discuss the diagnostic pathway, therapeutic approach and patient evolution. The case report proves that a comple
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42

Kasem, Mohamed, James Bentham, and John Thomson. "Single-centre experience in stenting arterial shunts for adult CHD patients with single-ventricle physiology and pulmonary blood flow dependent on arterial shunts." Cardiology in the Young 28, no. 12 (2018): 1431–35. http://dx.doi.org/10.1017/s1047951118001464.

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AbstractObjectivesThe objectives of this study were to describe the approach to stenting arterial shunts in adult congenital patients with single-ventricle physiology and to assess the medium-term clinical and haemodynamic outcomes following stent insertion.BackgroundAdult patients with single-ventricle physiology and pulmonary blood flow dependent on a surgically placed arterial shunt who did not progress to venous palliation are extremely challenging to manage. Progressive cyanosis secondary to narrowing of the shunt has a marked impact on exercise tolerance and results in intolerable well-b
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43

Erez, Eldad, David Bush, Vincent K. H. Tam, Nancy A. Doublin, and Jeanie Stakes. "Outcome in infants less than 3 kilograms for placement of saphenous venous homografts as systemic-to-pulmonary arterial shunts." Cardiology in the Young 18, no. 4 (2008): 386–91. http://dx.doi.org/10.1017/s1047951108002370.

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AbstractBackgroundEstablishing stable and adequate flow of blood to the lungs using a systemic-to-pulmonary arterial shunt in infants with low birth weight may involve significant morbidity and mortality. We reviewed our experience with this procedure in patients weighing less than 3 kilograms.MethodsBetween June, 2002, and June, 2007, we placed systemic-to-pulmonary arterial shunts in 32 infants weighing less than 3 kilograms, the range being 1.8 to 2.86 kg, with a median of 2.5 kg. The median age at placement of the shunt was 8 days, with a range from 2 to 70 days. In 17 patients (53%), the
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44

Kameny, Rebecca Johnson, Youping He, Catherine Morris, et al. "Right ventricular nitric oxide signaling in an ovine model of congenital heart disease: a preserved fetal phenotype." American Journal of Physiology-Heart and Circulatory Physiology 309, no. 1 (2015): H157—H165. http://dx.doi.org/10.1152/ajpheart.00103.2015.

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We recently reported superior right ventricle (RV) performance in response to acute afterload challenge in lambs with a model of congenital heart disease with chronic left-to-right cardiac shunts. Compared with control animals, shunt lambs demonstrated increased contractility because of an enhanced Anrep effect (the slow increase in contractility following myocyte stretch). This advantageous physiological response may reflect preservation of a fetal phenotype, since the RV of shunt lambs remains exposed to increased pressure postnatally. Nitric oxide (NO) production by NO synthase (NOS) is act
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45

Poerschke, Ronaldo André, Daniela Augustin Silveira, Peterson Lodi, Wagner Titton, Guilherme Marx, and Alexandre Soares Lampert. "Vascularização temporária de membros isquêmicos por meio de shunt arteriomedular: trabalho experimental." Jornal Vascular Brasileiro 11, no. 1 (2012): 29–33. http://dx.doi.org/10.1590/s1677-54492012000100006.

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CONTEXTO: Os autores idealizaram um shunt temporário entre a artéria femoral e o canal medular de ossos longos para manter a viabilidade dos membros agudamente isquêmicos, enquanto não é possível estabelecer um tratamento definitivo. OBJETIVO: Avaliar a perviedade de shunts temporários arteriomedulares e a perfusão dos membros, durante duas horas em cães de experimentação, que tiveram a artéria femoral ligada. MÉTODOS: Alocaram-se aleatoriamente dois grupos, com três cães no Grupo Controle e seis no Grupo Intervenção. Os controles tiveram a artéria femoral comum direita ligada. O Grupo Interve
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46

Murdoch, Ian A., Shakeel A. Qureshi, Rue Dos Anjos, Jonathan M. Parsons, Edward J. Baker, and Michael J. Tynan. "Hypercyanotic spells caused by antegrade catheterization of the pulmonary arteries in tetralogy of Fallot: fact or fiction?" Cardiology in the Young 1, no. 2 (1991): 136–40. http://dx.doi.org/10.1017/s1047951100000251.

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SummaryBetween January 1985 and March 1990, 66 children with the tetralogy of Fallot underwent 85 cardiac catheterization procedures. The mean age at first procedure was 2.5 years (range 0.1–;14.4 years) and the mean weight was 10.4 kg ( range 2.4–36.0 kg). Diagnostic cardiac catheterization was performed in 60 procedures and balloon dilatation in 25. Hypercyanotic spells had occurred prior to 24 (28%) of the procedures (all the patients being on propranolol) and a systemic-to-pulmonary arterial shunt had been constructed before 28 (33%) procedures. Of the procedures, 54 (64%) were performed u
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47

Stenbøg, Elisabeth V., Daniel A. Steinbrüchel, Anne Bloch Thomsen, et al. "The pulmonary vasculature in a neonatal porcine model with increased pulmonary blood flow and pressure." Cardiology in the Young 11, no. 4 (2001): 420–30. http://dx.doi.org/10.1017/s1047951101000543.

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Introduction: Hypertension and hyperperfusion of the pulmonary vascular bed in the setting of congenital cardiac malformations may lead to progressive pulmonary vascular disease. To improve the understanding of the basic mechanisms of this disease, there is a need for clinically relevant animal models which reflect the disease process. Material and Results: We randomly allocated 45 newborn pigs, at the age of 48 hrs, to groups in which there was either construction of a 3 mm central aorto-pulmonary shunt, undertaken in 9, or ligation of the left pulmonary artery, achieved in 13. Controls inclu
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48

Michel, R. P., T. S. Hakim, R. E. Hanson, A. R. Dobell, F. Keith, and D. Drinkwater. "Distribution of lung vascular resistance after chronic systemic-to-pulmonary shunts." American Journal of Physiology-Heart and Circulatory Physiology 249, no. 6 (1985): H1106—H1113. http://dx.doi.org/10.1152/ajpheart.1985.249.6.h1106.

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Congenital cardiac shunts produce pathological lesions on the arterial side of the lung vasculature. We examined the effects of chronic shunts (14.2 +/- 1.2 mo) in 10 young dogs, between the left subclavian and the left lower lobe (LLL) artery, on pulmonary vascular pressure and flow (P-Q) relationships, segmental resistance with arterial and venous occlusion (AVO), and sensitivity to drugs. At final thoracotomy, mean LLL pulmonary arterial pressure (Ppa) was 23.2 +/- 4.3 mmHg compared with 11.9 +/- 0.9 in the right lung (P less than 0.05); two animals had LLL Ppa of 41 and 48 mmHg. The LLL ar
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49

Vitanova, Keti, Stanimir Georgiev, Rüdiger Lange, and Julie Cleuziou. "Choice of shunt type for the Norwood I procedure: does it make a difference?" Interactive CardioVascular and Thoracic Surgery 30, no. 4 (2019): 630–35. http://dx.doi.org/10.1093/icvts/ivz294.

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Abstract OBJECTIVES This study aimed to compare pulmonary artery (PA) growth between patients who received a right ventricle-to-PA (RV–PA) shunt and those who received a modified Blalock–Taussig shunt (mBTS). METHODS All consecutive patients with hypoplastic left heart syndrome who underwent the Norwood I procedure between 2001 and 2017 were included in the study. Pre-stage 2 angiograms were analysed to measure the size of the PA. The Nakata index was calculated to estimate PA growth. The ratio of the right PA to left PA cross-sectional area (RPA/LPA) was used to calculate the difference in gr
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Sinelnikov, Yu S., V. B. Arutunyan, A. A. Porodikov та ін. "Application of mathematical modelling for the evaluation of the results of systemiс-pulmonary shunts formation". Patologiya krovoobrashcheniya i kardiokhirurgiya 24, № 3 (2020): 45. http://dx.doi.org/10.21688/1681-3472-2020-3-45-61.

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<p>Surgical treatment of congenital heart defects with the obstruction of the outflow tract of the right ventricle can be performed in several stages. The first stage of surgical correction is the creation of a systemic-pulmonary shunt, followed by radical correction. The main complications of systemic-pulmonary shunts are associated with the development of shunt thrombosis and hypervolemia of the pulmonary circulation. Currently, considering the importance of individual selection of a shunt for effective functioning, the main scientific search is aimed at creating optimal methods that c
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