Relevant bibliographies by topics / Sickle cell disease (SCD)

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Sickle cell disease (SCD)'

Author: Grafiati
Published: 4 June 2021
Last updated: 19 April 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Sickle cell disease (SCD).'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Sickle cell disease (SCD)"

1

Graziadei, Giovanna, Alessia Marcon, Martina Soldarini та ін. "Clinical Complications in Adult Patients with Sickle Cell Anemia and β-Thalassemia-Sickle Cell Disease". Blood 120, № 21 (2012): 4767. http://dx.doi.org/10.1182/blood.v120.21.4767.4767.

Full text
Abstract:
Abstract Abstract 4767 Background. Sickle-Cell Disease (SCD) is one of the most common severe monogenic inherited disorders worldwide, due to hemoglobin S (HbS), with reduced affinity for the oxygen. HbS polymerization, leading to erythrocyte rigidity, vaso-occlusion and hemolytic anemia, is central in the pathophysiology and crucial for the clinical outcome. The term SCD refers to Sickle Cell Anemia (SCA) due to homozygosis for βS allele, HbS/β-thalassemia (T-SCD) due to compound of β-thal and βS allele, and HbSC disease, owing to the coinheritance of βS and βcalleles. SCD is a multiorgan dis
APA, Harvard, Vancouver, ISO, and other styles
2

Blouin, Marie-José, Monique E. De Paepe, and Marie Trudel. "Altered Hematopoiesis in Murine Sickle Cell Disease." Blood 94, no. 4 (1999): 1451–59. http://dx.doi.org/10.1182/blood.v94.4.1451.

Full text
Abstract:
Abstract We investigated the mechanisms of sickle cell disease (SCD) hematopoietic/erythropoietic defects using bone marrow, spleen, and/or peripheral blood from the transgenic SAD mouse model, which closely reproduces the biochemical and physiological disorders observed in human SCD. First, the erythropoietic lineage late precursors (polychromatophilic normoblasts to the intramedullary reticulocytes) of SAD mouse bone marrow were significantly altered morphologically. These anomalies resulted from high levels of hemoglobin polymers and were associated with increased cell fragmentation occurri
APA, Harvard, Vancouver, ISO, and other styles
3

Blouin, Marie-José, Monique E. De Paepe, and Marie Trudel. "Altered Hematopoiesis in Murine Sickle Cell Disease." Blood 94, no. 4 (1999): 1451–59. http://dx.doi.org/10.1182/blood.v94.4.1451.416k02_1451_1459.

Full text
Abstract:
We investigated the mechanisms of sickle cell disease (SCD) hematopoietic/erythropoietic defects using bone marrow, spleen, and/or peripheral blood from the transgenic SAD mouse model, which closely reproduces the biochemical and physiological disorders observed in human SCD. First, the erythropoietic lineage late precursors (polychromatophilic normoblasts to the intramedullary reticulocytes) of SAD mouse bone marrow were significantly altered morphologically. These anomalies resulted from high levels of hemoglobin polymers and were associated with increased cell fragmentation occurring during
APA, Harvard, Vancouver, ISO, and other styles
4

Graziadei, Giovanna, Alessia Marcon, Ilaria Gandolfi, et al. "Splenic and Liver Involvement in Sickle Cell Disease." Blood 120, no. 21 (2012): 4763. http://dx.doi.org/10.1182/blood.v120.21.4763.4763.

Full text
Abstract:
Abstract Abstract 4763 Background. Sickle Cell Disease (SCD) is one of the most common severe monogenic inherited disorder worldwide characterized by the presence of hemoglobin S (HbS). HbS causes Hb polimerization leading to hemolytic anemia and vaso-occlusion due to erythrocyte rigidity, and is responsible of clinical acute events and chronic progressive multiorgan damage, which becomes evident with increasing age. The term SCD is used to refer to all the different genotypes: Sickle Cell Anemia (SCA) referring to homozygosis for βS allele; HbS/β-thalassemia, compound of β-thal and βS allele
APA, Harvard, Vancouver, ISO, and other styles
5

Ekong, Anietie. "Sickle cell disease." InnovAiT: Education and inspiration for general practice 10, no. 2 (2016): 73–81. http://dx.doi.org/10.1177/1755738015626186.

Full text
Abstract:
The haemoglobinopathies are the most common monogenetic diseases in the world. They include the thalassaemias and sickle cell syndromes. The sickle cell syndromes encompass several abnormal haemoglobin variants, of which homozygosity for the sickle cell gene – that is, sickle cell anaemia is the most common and most severe. Originally characteristic of the tropics and subtropics, recent mobility and migratory trends have meant that the prevalence of sickle cell disease (SCD) has significantly increased in the UK. It is important that GPs have an understanding of this disease, in order to help
APA, Harvard, Vancouver, ISO, and other styles
6

Faes, Camille, Anton Ilich, Amandine Sotiaux, et al. "Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease." Blood 133, no. 23 (2019): 2529–41. http://dx.doi.org/10.1182/blood.2019000424.

Full text
Abstract:
Abstract Sickle cell disease (SCD) is associated with chronic activation of coagulation and an increased risk of venous thromboembolism. Erythrocyte sickling, the primary pathologic event in SCD, results in dramatic morphological changes in red blood cells (RBCs) because of polymerization of the abnormal hemoglobin. We used a mouse model of SCD and blood samples from sickle patients to determine if these changes affect the structure, properties, and dynamics of sickle clot formation. Sickling of RBCs and a significant increase in fibrin deposition were observed in venous thrombi formed in sick
APA, Harvard, Vancouver, ISO, and other styles
7

Kumar, Priyatham. "Deep Vein Thrombosis and Pulmonary Embolism in Sickle Cell Disease." Biomedical Research and Clinical Reviews 1, no. 5 (2020): 01–04. http://dx.doi.org/10.31579/2692-9406/024.

Full text
Abstract:
Sickle Cell Disease (SCD) is considered a group of genetic red blood cell (RBC) disorders. Healthy red blood cells (RBC) are round in shape and migrates throughout the body to carry oxygen in the small blood vessels. In SCD, the RBC turns into hard and sticky, and the shape is similar to a C-Shaped tool called "SICKLE." Because of the early death of the sickle cells, a constant shortage of red blood cells arises. Because of the typical shape of the sickle cells, their movement in the blood vessel is not as smooth as normal RBC and get stuck and clog the blood flow leading to anemia. The change
APA, Harvard, Vancouver, ISO, and other styles
8

Jain, Dipty, Pooja Lodha, Roshan Colah, Prachi Atmapoojya, and Prachi Atmapoojya. "SICKLE CELL DISEASE AND PREGNANCY." Mediterranean Journal of Hematology and Infectious Diseases 11, no. 1 (2019): e2019040. http://dx.doi.org/10.4084/mjhid.2019.040.

Full text
Abstract:
Abstract
 
 Sickle Cell Disease (SCD) is a group of inherited single-gene autosomal recessive disorders caused by the ‘sickle’ gene, which affects haemoglobin structure. Sickle cell anemia is the most common hemoglobinopathy worldwide. The burden of sickle cell disease in pregnancy has been exponentially increasing with more number of women reaching the reproductive age, and having successful pregnancies. It has been proven beyond doubt that SCD in pregnancy poses the pregnant woman and fetus to significantly higher risks than a lady without SCD. SCD is associated with both maternal
APA, Harvard, Vancouver, ISO, and other styles
9

Voskaridou, Ersi. "Sickle Cell Disease Complications." Thalassemia Reports 4, no. 3 (2014): 4873. http://dx.doi.org/10.4081/thal.2014.4873.

Full text
Abstract:
Sickle cell disease (SCD) is an inherited, lifelong condition. The sickle mutation consists a single nucleotide change (GAT->GTT) in the sixth codon of exon 1 of the β-globin gene coding for the β-globin polypeptide of hemoglobin (Hb) (a2β2). This change results in replacement of the wild type glutamic acid residue by a valine residue in β-globin chain and the formation of the sickle Hb (HbS) in homozygotes for this mutation. Heterozygotes live a normal life. In SCD patients, sickle erythrocytes are rigid with decreased deformability and reduced life span resulting in hemolysis, vaso-occlus
APA, Harvard, Vancouver, ISO, and other styles
10

Field, Joshua J. "Can selectin and iNKT cell therapies meet the needs of people with sickle cell disease?" Hematology 2015, no. 1 (2015): 426–32. http://dx.doi.org/10.1182/asheducation-2015.1.426.

Full text
Abstract:
AbstractRecent insights into the pathogenesis of microvascular occlusion downstream of the sickled red cell have revealed new therapeutic targets for sickle cell disease (SCD). After the formation of sickle cells, tissue injury spurs inflammation, which leads to receptor-mediated contacts between sickle cells, leukocytes, and vascular endothelium. Specifically, selectins decelerate sickled red cells and leukocytes in the circulation to facilitate endothelial adhesion and other cell–cell interactions, ultimately leading to vascular occlusion. Invariant NKT (iNKT) cells, activated during reperfu
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Sickle cell disease (SCD)"

1

Goldstein, Alana L. "Transition Readiness in Adolescents and Young Adults with Sickle Cell Disease." Xavier University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=xavier1439143927.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Ralstrom, Elizabeth Frances. "The Impact of Oral Health in Adolescent Patients with Sickle Cell Disease." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1274754100.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

O'Brien, Julia Ann. "The Relationships Among Health Literacy, Stigma, Self-efficacy, Self-care, and Health Outcomes in Patients with Sickle Cell Disease." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1619721246113378.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Khizra, Shufa. "Using Natural Language Processing and Machine Learning for Analyzing Clinical Notes in Sickle Cell Disease Patients." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright154759374321405.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Soliman, Ashraf. "Study of growth and bone mineral density and factors affecting them in children and adolescents with thalassaemia major and sickle cell disease." Thesis, University of South Wales, 1998. https://pure.southwales.ac.uk/en/studentthesis/study-of-growth-and-bone-mineral-density-and-factors-affecting-them-in-children-and-adolescents-with-thalassaemia-major-and-sickle-cell-disease(9cd79851-b7a7-4df7-bb2d-65e71e48d6c4).html.

Full text
Abstract:
Thalassaemia and sickle cell disease (SCD) are the most widely distributed blood genetic disorders that occur at a high frequency in some populations including the Mediterranean region, parts of the Middle East, South East Asia and the Indian subcontinent. It is estimated that thalassaemia major affects 100,000 newborn every year world-wide. The high incidence of these chronic haemolytic diseases in developing countries poses a high load on the national economy because of the expensive treatment protocols and the considerably high morbidity rates of these patients. Repeated blood transfusion t
APA, Harvard, Vancouver, ISO, and other styles
6

Ibrahim, Christine. "Exploring the role of the activin A-ActRIIB pathway in sickle cell disease-associated nephropathy and sarcopenia : mechanistic insights and therapeutic potential." Electronic Thesis or Diss., Université Paris Cité, 2024. http://www.theses.fr/2024UNIP5287.

Full text
Abstract:
La drépanocytose est une maladie génétique caractérisée par des crises vaso-occlusives récurrentes et des lésions multi-organes progressives, y compris des atteintes rénales et une perte musculaire, qui aggravent la morbidité et réduisent la qualité de vie des patients. Bien que les mécanismes sous-jacents de la néphropathie associée à la drépanocytose soient bien établis, les facteurs responsables de l'atrophie musculaire restent partiellement compris. Des données récentes suggèrent qu'Activine A, un membre de la superfamille TGF-β, joue un rôle significatif dans la fibrose et la progression
APA, Harvard, Vancouver, ISO, and other styles
7

Rampazzo, Patrizia. "Studio Multidisciplinare sulle complicanze neurologiche in bambini affetti da Anemia Falciforme Valutazione con metodiche Ultrasonografiche, Neuroradiologiche, test Neuropsicologici e Neurofisiologici." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422184.

Full text
Abstract:
ABSTRACT Sickle cell disease (SCD) is a genetic disorder caused by abnormal haemoglobin that damages and deforms red blood cells. Sickle cell anemia (SCA) is the most severe form of SCD developing when two sickle genes are inherited (homozygotic HbSS) . Sickle cell disease is in the world, the most common genetic disease. Each year more than 300,000 children are born with SCD, mainly in Africa, India and Albania (data WHO 2008). The SCA is an increasing global health problem (Weatherall DJ 2001) . Neurologic complications are frequent among the most serious and disabling. Stroke is a freq
APA, Harvard, Vancouver, ISO, and other styles
8

Aufradet, Émeline. "Drépanocytose et activité physique : conséquences sur les mécanismes impliqués dans l'adhérence vasculaire, l'inflammation et le stress-oxydatif." Thesis, Lyon 1, 2012. http://www.theses.fr/2013LYO10007/document.

Full text
Abstract:
La drépanocytose est, sous sa forme grave, une pathologie très invalidante pour les personnes qui en sont porteuses. Elle est rythmée par la récurrence de crises vaso-occlusives (CVO) et autres symptomatiques qui en découlent (accident vasculaire cérébral, syndrome thoracique aigu, hypertension pulmonaire, etc.). En participant, chez des sujets sains et pathologiques, à la limitation de certains facteurs impliqués dans les CVO (inflammation, adhésion vasculaire, stress-oxydatif), l'entrainement physique régulier pourrait hypothétiquement être bénéfique au sujets drépanocytaires et participer à
APA, Harvard, Vancouver, ISO, and other styles
9

Tozatto, Maio Karina. "Immunogenetics in sickle cell disease." Thesis, Sorbonne Paris Cité, 2019. http://www.theses.fr/2019USPCC093.

Full text
Abstract:
La drépanocytose est l’hémoglobinopathie héréditaire la plus fréquente, causée par un polymorphisme unique d’un nucléotide (SNP) dans le gène de la beta-globine (HBB). Ce SNP détermine la synthèse de l’hémoglobine S, qui polymérise lorsqu’elle est soumise au stress, et ceci change la forme des hématies drépanocytaires en faucille. Les drépanocytes sont moins déformables, plus adhérents à l’endothélium, et plus susceptibles à l’hémolyse. Les complications cliniques de la drépanocytose peuvent être expliquées par l’interaction entre la vaso-occlusion, l’hémolyse et l’activation inflammatoire rés
APA, Harvard, Vancouver, ISO, and other styles
10

Hays, Mary Margaret. "Stem cell transplant for sickle cell disease." Thesis, Boston University, 2013. https://hdl.handle.net/2144/12117.

Full text
Abstract:
Thesis (M.A.)--Boston University<br>Background: Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. As SCD can cause significant morbidity and decrease in life expectancy, further research on curative options is of great interest. Hematopoietic stem cell transplant (HSCT) is the only treatment option offering a chance of cure, but the risks of treatment are not negligible. Because the outcomes of HSCT are best when the procedure is performed at a younger age, understanding what parents know about transplant, their opinion on this option and the risks the
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Sickle cell disease (SCD)"

1

Peak, Lizabeth. Sickle cell disease. Lucent Books, 2008.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Peak, Lizabeth. Sickle cell disease. Lucent Books, 2008.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

Serjeant, Graham R. Sickle cell disease. 2nd ed. Oxford University Press, 1992.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

F, Whitten Charles, Bertles John F. 1925-, National Association for Sickle Cell Disease (U.S.), and New York Academy of Sciences., eds. Sickle cell disease. New York Academy of Sciences, 1989.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Eboh, Winifred Oluchukwu. Sickle cell disease. Birmingham Sickle Cell & Thalassaemia Centre, 1993.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Jones, Phill. Sickle cell disease. Chelsea House, 2008.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

Samuel, Charache, and Johnson Cage S, eds. Sickle cell disease. W.B. Saunders, 1996.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

McCormick, Marie, Henrietta Awo Osei-Anto, and Rose Marie Martinez, eds. Addressing Sickle Cell Disease. National Academies Press, 2020. http://dx.doi.org/10.17226/25632.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

P, Rodgers Griffin, ed. Sickle cell disease and thalassaemia. Baillière Tindall, 1998.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

author, Chilman-Blair Kim, and DeLoache Shawn author, eds. Medikidz explain sickle cell disease. Medikidz Ltd., 2013.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Sickle cell disease (SCD)"

1

Maricle, Denise E., and Allante Lumas. "Sickle Cell Disease (SCD)." In Understanding and Managing Neurodevelopmental Disorders in Children and Adolescents. Routledge, 2025. https://doi.org/10.4324/9781032703923-20.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Nwankwo, Kanayo, and Sophie Uyoga. "Transfusion in Sickle Cell Disease (SCD)." In Sickle Cell Disease in Sub-Saharan Africa. Routledge, 2024. http://dx.doi.org/10.4324/9781003463931-12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Anderson, Claire L., and Deepika S. Darbari. "Current Non-HSCT Treatments for SCD." In Sickle Cell Disease and Hematopoietic Stem Cell Transplantation. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62328-3_3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Adamu-Oyegun, Scott. "The Challenge of Data with SCD." In Sickle Cell Disease in Sub-Saharan Africa. Routledge, 2024. http://dx.doi.org/10.4324/9781003467748-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Cappelli, Barbara, Eliane Gluckman, Selim Corbacioglu, Josu de la Fuente, and Miguel R. Abboud. "Hemoglobinopathies (Sickle Cell Disease and Thalassemia)." In The EBMT Handbook. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-44080-9_80.

Full text
Abstract:
AbstractHematopoietic cell transplantation (HCT) using an HLA-matched sibling donor is a well-established curative therapy for pediatric patients with sickle cell disease (SCD) and transfusion-dependent thalassemias (TDT). In order to expand the donor pool, new approaches such as related haploidentical donor HCT have been used with encouraging results. These approaches aim for a higher overall survival, an effective reduction of acute and chronic GvHD and a reduced toxicity. Due to these alternative approaches and adult patients being increasingly transplanted, the number of HCT has dramatically increased in the last decade. Furthermore, different gene therapy and gene editing strategies are being developed in clinical trials, showing promising results.
APA, Harvard, Vancouver, ISO, and other styles
6

Badamosi, Nnenna Ukachi. "Routine Comprehensive Care for Children with SCD." In Sickle Cell Disease in Sub-Saharan Africa. Routledge, 2024. http://dx.doi.org/10.4324/9781003463931-6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Iradukunda, Cynthia. "Sickle Cell Disease (SCD) and Perioperative Pain Management." In Perioperative Pain Management. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-67648-2_24.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Hatabah, Dunia, and Miguel Abboud. "Investigational Therapies and Advances in Science for SCD." In Sickle Cell Disease in Sub-Saharan Africa. Routledge, 2024. http://dx.doi.org/10.4324/9781003463931-17.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Sarki, Ahmed Mohammed, Lilian Nuwabaine, and Sabrina Bakeera-Kitaka. "Management of Infections and Fever in Sickle Cell Disease (SCD)." In Sickle Cell Disease in Sub-Saharan Africa. Routledge, 2024. http://dx.doi.org/10.4324/9781003463931-11.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Berghs, Maria. "The Critical Importance of Global Collaboration in SCD Advocacy and Management." In Sickle Cell Disease in Sub-Saharan Africa. Routledge, 2024. http://dx.doi.org/10.4324/9781003467748-8.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Sickle cell disease (SCD)"

1

Liang, Jiebin, Yunhyuk Chang, Jinhyeok Kim, Zhiyuan Li, John Canevari, and Sasan Haghani. "Sickle Cell Disease Patient/Provider Match Tool." In 2024 IEEE International Humanitarian Technologies Conference (IHTC). IEEE, 2024. https://doi.org/10.1109/ihtc61819.2024.10855129.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Highland, Robert E., Cindy X. Chen, David A. Miller, Chao-Chieh Lin, Jen-Tsan A. Chi, and Adam Wax. "Examining sickle cell disease using high-throughput holographic cytometry." In Quantitative Phase Imaging XI, edited by YongKeun Park and Yang Liu. SPIE, 2025. https://doi.org/10.1117/12.3044015.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Wu, Runxin, Mohammed Shihab Kabir, George A. Truskey, and Amanda Randles. "Investigating the impact of sickle cell disease on red blood cell transport in complex capillary networks." In 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2024. https://doi.org/10.1109/embc53108.2024.10781578.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Brum, Igor Vilela, Guilherme Diogo Silva, Diego Sant'Ana Sodre, Felipe Melo Nogueira, Samira Luisa dos Apostolos Pereira, and Luiz Henrique Martins Castro. "Myelopathy in sickle cell disease: a case-oriented review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.563.

Full text
Abstract:
Background: Although neurological complications are well recognized in sickle cell disease (SCD), myelopathy has been rarely described. We present the first case report of longitudinally extensive myelitis (LETM) in SCD and review the differential diagnosis of myelopathy in these patients. Design and setting: case-oriented review. Methods: We report the case of a 29-year-old African-Brazilian man with SCD, who experienced a subacute flaccid paraparesis, with T2 sensory level and urinary retention. CSF analysis showed a lymphocytic pleocytosis and increased protein levels. MRI disclosed a longi
APA, Harvard, Vancouver, ISO, and other styles
5

Glas-Greenwalt, P., J. Palascak, R. Gruppo, D. Stroop, and V. Pollak. "DEFECTIVE FIBRINOLYSIS IN SICKLE CELL DISEASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644838.

Full text
Abstract:
Vasocclusive crises (VOC) cause significant morbidity and mortality in sickle cell disease (SCD). Although sickling is thought to be the predominant factor in VOC, investigators have examined the possible role of the hemostatic mechanism in the process. The data are, however, inconsistent. We studied, functionally with the fibrin plate method, the fibrinolytic system in 36 adults in the steady state and in 8 children, 7 of whom suffered from painful crises. Values in 240 normal blood donors were: tissue-type plasminogen activator activity (t-PA); 3-25 activator units/ml, corresponding to 0.04
APA, Harvard, Vancouver, ISO, and other styles
6

Dautzenberg, M. D., F. Monge, A. M. Fischer, R. Girot, and P. Cornu. "COAGULATION AND FIBRINOLYSIS IN SICKLE CELL DISEASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643056.

Full text
Abstract:
Sickled erythocytes appear to be primarily responsible for occlusion of microvasculature in patients with homozygous sickle cell disease (SCD), but it is unknown whether the activation of the coagulation pathway is also contributory to these vaso-occlusive crisis and other complications as leg ulcers, aseptic necrosis of bone, strokes. Thus, we studied coagulation and fibrinolysis parameters in 12 patients (ages 2 to 26 years with SCD, in steady-state, far from thrombotic events which occurred in 3 of them) to determine if it would be possible to detect a high-risk group for thrombosis. We wer
APA, Harvard, Vancouver, ISO, and other styles
7

Chamone, D. A. F., A. Y. Hoshikawa-Fujimura, C. Massumoto, G. Bellotti, F. Arashiro, and M. Jamra. "ABNORMALITIES OF PLATELET AGGREGATION AND ENHANCED FACTOR X ACTIVATOR ACTIVITY OF WASHED PLATELETS IN SICKLE CELL DISEASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644544.

Full text
Abstract:
The occurence of microvascular occlusion is one of the most prominent pathologic features of sickle cell anemia. The mechanism of vaso occlusion has generally been attributed to the abnormal shape and reduced deformability of the sickled erithrocy tes. However, the involvement of vascular endothelium, platelets and their interactions with coagulation factors may also be of pathogenic significance in microvascular occlusive crises.We investigated the interaction between vascular endothelium, platelets and blood coagulation factors in 23 patients with Sickle Cell Disease (SCD) and in normal volu
APA, Harvard, Vancouver, ISO, and other styles
8

Maciaszek, J. L., B. Andemariam, and G. Lykotrafitis. "Red Blood Cell Surface Receptor Expression of BCAM/Lu is Regulated by Protein Kinase A Activity." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14311.

Full text
Abstract:
Irregular sickle red blood cells (RBCs) can contribute to the pathogenesis of vasoocclusion and other complications of sickle cell disease (SCD) via abnormal adherence to the vascular endothelium. It has previously been demonstrated that epinephrine enhances SCD RBC adhesion by activating the BCAM/Lu and ICAM-4 surface receptors [1–2]. Epinephrine acts on the RBC β2-adrenergic receptor, thereby activating Gas proteins that stimulate adenylyl cyclase (AC). This enzyme catalyzes the conversion of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP), leading to protein kinase A (
APA, Harvard, Vancouver, ISO, and other styles
9

Awuor, Silas Onyango, and Fidelma C. Too. "Association of Sickle Cell Disease with Nutritional Status Among Under-Five Children and Mediating Role of Hemoglobin Level: Secondary Analysis of Data From 2020-2022 Demographic and Health Survey." In 3rd International Nutrition and Dietetics Scientific Conference. KENYA NUTRITIONISTS AND DIETICIANS INSTITUTE, 2023. http://dx.doi.org/10.57039/jnd-conf-abt-2023-m.i.y.c.n.h.p-31.

Full text
Abstract:
Background: Malnourishment remains the main issue that affect under-five children in Kenya to an overwhelming proportion. The condition is further compounded by the burden of sickle cell disease (SCD). However, association of SCD with stunting, wasting, and underweight in a nationally representative sample of under-five children remains unknown. The main aim of this study was to describe prevalence of under malnutrition by sickle cell status, to evaluate its association with growth faltering ascertained with anthropometric indices, and to explore mediating role of hemoglobin. Methods: The data
APA, Harvard, Vancouver, ISO, and other styles
10

Nguka, Prof Gordon. "Nutrition and Dietetics Lens in the Management Sickle Cell Disease." In 3rd International Nutrition and Dietetics Scientific Conference. KENYA NUTRITIONISTS AND DIETICIANS INSTITUTE, 2023. http://dx.doi.org/10.57039/jnd-conf-knt-2023-004.

Full text
Abstract:
SICKLE CELL disease is the most common severe monogenic disorder in humans. In Africa, 50–90% of children born with sickle cell disease die before they reach their fifth birthday. A cure for sickle cell anemia (SCA) is not available to all who have inherited this devastating genetically inherited disease. However, increasing knowledge that nutritional imbalances are fundamental to the severity of the disease, has produced interest in promoting dietary and nutrition intervention for treating these patients. This review seeks to emphasize the understanding that both children and adults with sick
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Sickle cell disease (SCD)"

1

Santos Garcia, João Batista, and Ana Laura Schwartzmann Bruno. Pain in Sickle Cell Disease and Acute Varicella Zoster Pain. World Federation of Societies of Anaesthesiologists, 2024. https://doi.org/10.28923/atotw.537.

Full text
Abstract:
This tutorial addresses the etiology and management of pain associated with sickle cell disease and acute pain related to varicella zoster. Both are severe pain conditions with a significant impact on individuals' functionality and the potential to cause substantial suffering.
APA, Harvard, Vancouver, ISO, and other styles
2

Paul, Satashree. Turning Back the Sickle Cell Disease: A New Drug into Play. Science Repository OÜ, 2021. http://dx.doi.org/10.31487/sr.blog.38.

Full text
Abstract:
Researchers at the Fulcrum Therapeutics developed a bioavailable drug candidate called FTX 6058 – (a novel small molecular fetal haemoglobin inducer for sickle cell disease) that can restore the body’s ability to produce fetal haemoglobin
APA, Harvard, Vancouver, ISO, and other styles
3

Krishnamurti, Lakshmanan, Deepika Darbari, Victor Gordeuk, et al. Can Personalized Encouragement Help People With Sickle Cell Disease Take Hydroxyurea Therapy Regularly? Patient-Centered Outcomes Research Institute® (PCORI), 2020. http://dx.doi.org/10.25302/05.2020.ce.13046859em.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Yu, Winifred W., Tanvi Reddy, and Melissa Barnhart. Dental Care for People With Sickle Cell Disease: A Rapid Response Literature Review. Agency for Healthcare Research and Quality (AHRQ), 2024. http://dx.doi.org/10.23970/ahrqepcrapid_dental_sicklecell.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Lanzkron, Sophie, Jane Little, Joshua Field, et al. Comparing Pain Management for Sickle Cell Disease Crises in Emergency Rooms and Infusion Centers. Patient-Centered Outcomes Research Institute (PCORI), 2020. http://dx.doi.org/10.25302/08.2020.ihs.140311888.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Krishnamurti, Lakshmanan, Diana Ross, Nitya Bakshi, Cynthia Brown Sinha, and Geoerge Loewenstein. An Online Decision Aid to Help Patients and Caregivers Decide on Treatments for Sickle Cell Disease. Patient-Centered Outcomes Research Institute® (PCORI), 2020. http://dx.doi.org/10.25302/1.2020.ce.12114318em.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Marques, Carla, Larissa Lopes, Rita Lucena, and Abrahão Baptista. Brain morphofunctional changes associated with pain in children, adolescents and young adults with sickle cell disease. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.12.0022.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Crosby, Lori, Constance Mara, Yolanda Johnson, Rogelle Hackworth, and Charles Quinn. Comparing Ways to Help Parents of Children with Sickle Cell Disease Decide on Treatment -- The ENGAGE HU Study. Patient-Centered Outcomes Research Institute (PCORI), 2024. http://dx.doi.org/10.25302/02.2024.cdr.160936055.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Amponsah, Isaac, Denzel Opoku-Kwabi, Francis Ackah Armah, John Nii Addotey, Bernard Kofi Turkson, and Emmanuel Quaye Kontoh. A systematic review of validated medicinal plants and their compounds as agents for the management of sickle cell disease. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.4.0121.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Desai, Payal, Raymona Lawrence, Myra Robinson, et al. Comparing the Effects of Peer Mentoring on Care Transitions in Emerging Adults with Sickle Cell Disease: The ST3P-UP Study. Patient-Centered Outcomes Research Institute (PCORI), 2024. http://dx.doi.org/10.25302/11.2024.mcsc.160835861.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Sickle cell disease (SCD)' for particular source types:
Journal articles Dissertations / Theses Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography