Academic literature on the topic 'Sida cordifolia'

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Journal articles on the topic "Sida cordifolia"

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Urmi, Amina Begum, Arjina Akter Ankhi, Md Aminul Islam, et al. "Comprehensive Evaluation of the Antihyperlipidemic Effects of Sida cordifolia in Rodent Models." Journal of Complementary and Alternative Medical Research 26, no. 5 (2025): 102–8. https://doi.org/10.9734/jocamr/2025/v26i5659.

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Hyperlipidemia is a major risk factor for cardiovascular diseases and metabolic disorders, necessitating the development of safe and effective therapeutic agents. Sida cordifolia, a medicinal plant traditionally used in Ayurvedic medicine, has shown potential lipid-lowering properties. This study aimed to comprehensively evaluate the antihyperlipidemic effects of Sida cordifolia extracts in rodent models. Wistar albino rats were divided into normal control, hyperlipidemic control, standard (atorvastatin-treated), and test groups treated with ethanolic and aqueous extracts of Sida cordifolia at varying doses. Hyperlipidemia was induced using a high-fat diet. Serum lipid profiles—including total cholesterol, triglycerides, LDL-C, and HDL-C—were measured at baseline and post-treatment. Histopathological analysis of liver tissues was also performed to assess hepatic integrity. Results indicated a significant reduction in total cholesterol, triglycerides, and LDL-C, with a concurrent increase in HDL-C levels in Sida cordifolia-treated groups, particularly at higher doses. Histological findings supported biochemical results, showing reduced lipid accumulation and improved hepatic architecture. These findings suggest that Sida cordifolia possesses potent antihyperlipidemic activity, supporting its potential use as a natural therapeutic agent for managing dyslipidemia. These findings position Sida cordifolia as a promising natural candidate for the management of hyperlipidemia, warranting further clinical validation and standardization for therapeutic use.
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Sharma, Bhupendra, Rishi Dewangan, and Shyam Sharma. "Characterizing the mechanical behavior of eco-friendly hybrid polymer composites with jute and Sida cordifolia fibers." Metal Working and Material Science 26, no. 3 (2024): 267–85. http://dx.doi.org/10.17212/1994-6309-2024-26.3-267-285.

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Introduction. Recognition of the medicinal properties of plants is an integral part of traditional Indian health systems such as Unani, Siddha, Naturopathy and Ayurveda. Among others, Sida cordifolia, a member of the Malvaceae family, is especially celebrated in Ayurvedic medicine for its outstanding chemical properties. This plant grows in the subtropical and tropical climate of India and symbolizes the global shift towards more environmentally friendly materials. Given the rising environmental concerns, there is an increased demand for biodegradable and renewable resources for industrial applications, especially for reinforcing polymer matrices with natural fibers. The purpose of this study is to investigate the effectiveness of Sida cordifolia fibers combined with jute for reinforcing polylactic acid (PLA) composites. This highlights its potential to improve both environmental quality and mechanical properties of materials. Materials and method. The study involved the fabrication of four different composite specimens: : a solely 4-layered jute fiber mat, untreated Sida cordifolia fibers combined with a 4-layered jute mat, and Sida cordifolia fibers treated with benzoylation combined with a 4-layered jute mat. These composites were subjected to mechanical testing focusing on tensile strength and flexural strength. Its microstructural analysis was also carried out. Results and discussion. The results show that benzoylation-treated Sida cordifolia fibers exhibit significantly higher strength compared to its untreated counterparts. At the same time, an increase in the proportion of Sida cordifolia fibers in composites while maintaining a constant total mass correlates with an increase in the strength of the materials. These results indicate that Sida cordifolia and jute fiber-reinforced PLA composites can provide a competitive, environmentally friendly alternative to synthetic fiber-reinforced composites in a variety of industrial applications. In conclusion, treated natural fibers like Sida cordifolia can significantly improve the mechanical properties of polymer composites, supporting its use as environmentally friendly, high-performance materials in a variety of industries. This research not only promotes the use of natural fibers for commercial applications, but also contributes to the larger goal of sustainable materials science.
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Sutradhar, Ranajit K., A. K. M. Matior Rahman, Mesbah U. Ahmad, and Sitesh C. Bachar. "Bioactive flavones of Sida cordifolia." Phytochemistry Letters 1, no. 4 (2008): 179–82. http://dx.doi.org/10.1016/j.phytol.2008.09.004.

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Nishigandha, Yadav* Poorva Bhailume Tanaya Birdawade Vaishnavi Divekar Hrishita Shetty Angad Yelwe. "Zingiber Officinale and Sida Cordifolia as Nature's Defenders: Exploring their Action Against Inflammation and Parasite." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1979–85. https://doi.org/10.5281/zenodo.15228778.

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Inflammation and parasitic infections pose significant health challenges, requiring effective and sustainable treatment approaches. This study investigates the anti-inflammatory and anthelmintic properties of Zingiber officinale (ginger) and Sida cordifolia, two medicinal plants traditionally used for their therapeutic effects. Using an egg albumin denaturation assay, the anti-inflammatory potential of these plant extracts was assessed, demonstrating a dose-dependent inhibition of protein denaturation. Notably, the combined extract of Sida cordifolia and ginger exhibited a synergistic effect, approaching the efficacy of Diclofenac sodium. Likewise, anthelmintic activity was evaluated using Pheretima posthuma (earthworms) as a biological model. Results revealed that ginger induced faster paralysis and death of the worms compared to Sida cordifolia alone, while their combination displayed enhanced potency, comparable to the standard drug Albendazole. These findings highlight the therapeutic prospects of Sida cordifolia and ginger as natural alternatives for managing inflammation and parasitic infections, supporting their traditional use and encouraging further pharmacological exploration.
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Arshad, S., I. Hussain, M. Ibrahim, et al. "Biochemical studies on protein, phenolic contents and antioxidant activities of Sida cordifolia extracts." Bulletin of the Chemical Society of Ethiopia 34, no. 2 (2020): 427–34. http://dx.doi.org/10.4314/bcse.v34i2.18.

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The study aimed to characterize the antioxidant properties regarding the Sida cordifolia with special reference to its detailed biochemical analysis. The study revealed that chlorophyll A (0.9 ± 0.3 mg/g), total chlorophyll content (3.0 ± 0.7 mg/g), total carotenoid content (0.3 ± 0.1 mg/g), total soluble proteins (7.5 ± 0.1 mg/g), and total phenolic contents (5.6 ± 1.3 mg/g) were found highest in flower tissue of S. cordifolia. However, peroxidase (POD) contents (118 ± 31 units/g), superoxide dismutase (SOD) activity (64 ± 1.5 units/g) were maximum in the leaf tissues, while catalase (CAT) contents (133 ± 25 units/g), ascorbate peroxidase (APX) contents (145 ± 44 units/g) were also found more in the flowers of S. cordifolia rather than other parts. Our results conclude that leaves, stem, flower of S. cordifolia could be exploited in pharmacology due to presence of different antioxidants reflected in flower and leaf extract make them potent and profound therapeutic agents.
 
 KEY WORDS: Alkaloids, Flavonoids, Phenolics, Antioxidant, Sida cordifolia
 
 Bull. Chem. Soc. Ethiop. 2020, 34(2), 427-434
 DOI: https://dx.doi.org/10.4314/bcse.v34i2.18
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Bianco, S., L. B. Carvalho, and M. S. Bianco. "Estimativa da área foliar de Sida cordifolia e Sida rhombifolia usando dimensões lineares do limbo foliar." Planta Daninha 26, no. 4 (2008): 807–13. http://dx.doi.org/10.1590/s0100-83582008000400012.

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A estimativa da área foliar pode auxiliar na compreensão de relações de interferência entre plantas daninhas e cultivadas. Com o objetivo de obter uma equação que, por meio de parâmetros lineares dimensionais das folhas, permita a estimativa da área foliar de Sida cordifolia e Sida rhombifolia, estudaram-se as correlações entre área foliar real (Af) e parâmetros dimensionais do limbo foliar, como o comprimento (C) ao longo da nervura principal e a largura máxima (L) perpendicular à nervura principal. Foram analisados 200 limbos foliares de cada espécie, coletados em diferentes agroecossistemas na Universidade Estadual Paulista, campus de Jaboticabal. Os modelos estatísticos utilizados foram linear: Y = a + bx; linear simples: Y = bx; geométrico: Y = ax b; e exponencial: Y = ab x. Todos os modelos analisados podem ser empregados para estimação da área foliar de S. cordifolia e S. rhombifolia. Sugere-se optar pela equação linear simples, envolvendo o produto C*L, considerando-se o coeficiente linear igual a zero, em função da praticidade desta. Desse modo, a estimativa da área foliar de S. cordifolia pode ser obtida pela fórmula Af = 0,7878*(C*L), com coeficiente de determinação de 0,9307, enquanto para S. rhombifolia a estimativa da área foliar pode ser obtida pela fórmula Af = 0,6423*(C*L), com coeficiente de determinação de 0,9711.
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BARACHO, GEORGE SIDNEY, and MARIA DE FÁTIMA AGRA. "New synonyms and lectotypifications in Sida (Malvaceae-Malveae) reveal the first record and extension of the distribution area of Sida maculata to Brazil." Phytotaxa 660, no. 3 (2024): 287–93. http://dx.doi.org/10.11646/phytotaxa.660.3.6.

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New synonyms and lectotypes in Sida sect. Cordifoliae (Malvaceae, Malveae) are proposed here and reveal the first record and extension of the distribution area of Sida maculata to the Brazilian semi-arid region. The species was first described in the 18th century for the Caribbean islands of Cuba and the Dominican Republic and for a long time was confused with S. cordifolia, from which it is unquestionably distinct in its leaves, inflorescences and flowers. In Brazil, S. maculata is widely distributed from Maranhão to the north of Minas Gerais and was identified for almost a century in herbaria and local floristic treatments as S. galheirensis. Discussions and photographs of types of S. maculata and related taxa are presented, as well as an updated map of the species’ geographical distribution.
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Uko, Ogwo Elisha, Obioma Elizabeth Nweke, Okoye Ogochukwu Fidelis, Ubani Clement Dimgba, and Suleiman Ali Sani. "Biochemical and Haematological Effects of Aqueous Leaf Extract of Sida cordifolia in Plasmodium beighei Infected Wistar Rats." International Journal of Pathogen Research 13, no. 3 (2024): 1–5. http://dx.doi.org/10.9734/ijpr/2024/v13i3280.

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Assessment of haematological and biochemical parameters can be predictive of the adverse effects resulting from ingesting foreign substances. Thus, the aim of this study was to evaluate the biochemical and haematological indices in Plasmodium beighei infected wistar rats. Freshly harvested leaves of Sida cordifolia were washed and dried at room temperature, after which they were ground to fine powder and subsequently extracted. Twenty-five adult Wistar rats were divided into five groups of five rats each. Group I was the normal control and was administered 2 ml of distilled of water. Group II was infected without treatment, while Group III and IV were infected and afterwards administered 200 and 400 mg/kg of aqueous extract of Sida cordifolia respectively. Group V was administered the standard drug. Biochemical and haematological indices were determined using standard procedures. The Packed Cell Volume (PCV) reported for group II (negative) control was significantly (P<0.05) lower than that reported for the normal control. However, oral administration of 200 and 400 mg/kg of Sida cordifolia leaf extract significantly (P<0.05) increased it, though to a level which was significantly (P<0.05) lower than that reported for the normal control. Similar observation was made on Haemoglobin Concentration (Hb) and Red Blood Cell (RBC). However, a contrary observation was made on the white blood cell. Urea and creatinine reported for the negative control were significantly (P<0.05) higher than those reported for the normal control. However, the aforementioned parameters were significantly (P<0.05) reduced following oral administration of Sida cordifolia. In conclusion, it can be deduced from this study that Sida cordifolia leaf extract has the ability to restore distorted haematological and biochemical status resulting from P. berghei infection.
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Silva, Renata Lemos, Gustavo Barreto de Melo, Valdinaldo Aragão de Melo, et al. "Effect of the aqueous extract of Sida cordifolia on liver regeneration after partial hepatectomy." Acta Cirurgica Brasileira 21, suppl 1 (2006): 37–39. http://dx.doi.org/10.1590/s0102-86502006000700009.

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PURPOSE: The use of medicinal plants for the treatment of human diseases has increased worldwide. Many of them are used by oral administration and, after absorption, may affect many organs. Therefore, this study aimed at assessing the effects of the aqueous extract of Sida cordifolia leaves, popularly known in Brazil as "malva-branca", on liver regeneration. METHODS: Twenty rats were divided into four groups: control, Sida100, Sida200 and Sida400 groups. All animals were submitted to oral administration of distilled water, 100, 200 and 400 mg/kg of the aqueous extract of Sida cordifolia, respectively. Immediately after this, they underwent 67% partial hepatectomy. Twenty four hours later, their livers were removed. Hepatic regeneration was assessed by immunohistochemical staining for proliferating cell nuclear antigen (PCNA) using the PC-10 monoclonal antibody. RESULTS: Sida100 and Sida200 groups disclosed higher liver regeneration indices than control group (p<0.001 and p<0.05, respectively). CONCLUSION: The aqueous extract of Sida cordifolia stimulates liver regeneration after 67% partial hepatectomy in rats.
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GODARA, R., S. I. RAFIQI, R. SHARMA, et al. "Acaricidal activity of Alstonia scholaris and Sida cordifolia leaf extracts against Hyalomma anatolicum ticks." Indian Journal of Animal Sciences 90, no. 11 (2021): 1461–64. http://dx.doi.org/10.56093/ijans.v90i11.111487.

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Development of acaricidal resistance and environmental pollution has driven need for eco-friendly pesticides and herbal acaricides. Leaf extracts of Alstonia scholaris and Sida cordifolia in four different solvents were used in the range of 0.25-8.0% for larval immersion test against unfed larvae of Hyalomma anatolicum. Mortality rates of larval ticks were in dose-dependent manner ranged from 0.5 to 100% for A. scholaris and from 0.8 to 100% for S. cordifolia. Acetone extract of A. scholaris and methanolic extract of S. cordifolia were most effective against larval ticks with LC50 values of 0.71% and 0.42%, respectively. Significant larvicidal activity of A. scholaris and S. cordifolia leaf extracts against unfed larvae of H. anatolicum qualify them as green pesticides which could be combined with other tools for integrated pest management.
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Dissertations / Theses on the topic "Sida cordifolia"

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Silva, Adailton Martins. "Avaliação do efeito antinociceptivo orofacial da Sida cordifolia L. (Malvaceae) em roedores." Universidade Federal de Sergipe, 2011. https://ri.ufs.br/handle/riufs/3703.

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Sida cordifolia from Malvaceae family (Sida L.) with about 250 species around the world, has been used in folk medicine as anti-inflammatory, antirheumatic and antipyretic, laxative, diuretic, analgesic and hypoglycemic, antiviral, bactericide and antifungal. In this study, we attempted to identify the possible antinociceptive action of the ethanol extract (EE), chloroform (CF) and methanol (MF) fractions obtained of Sida cordifolia, known in Brazil as malva branca or malva branca sedosa . Leaves of S. cordifolia were used to produce the crude ethanol extract and after CF and MF. Experiments were conducted on Swiss mice using the glutamate and formalin-induced orofacial nociception. In the formalin test, all doses of EE, CF and MF significantly reduced the orofacial nociception in the first (p < 0.001) and second phase (p < 0.001), which was also naloxone-sensitive. The percentage reduction average for the first phase of the formalin test was 79,6% (EE), 78,4% (CF) e 65,6% (MF) and for the second phase 77,9% (EE), 69,7% (CF) e 81,1% (MF). In the glutamate-induced nociception test, only CF and MF significantly reduced the orofacial nociceptive behavior with inhibition percentage values of 48.1% (100 mg/kg, CF), 56.1% (200 mg/kg, CF), 66.4% (400 mg/kg, CF), 48.2 (200 mg/kg, MF) and 60.1 (400 mg/kg, MF). Furthermore, treatment of the animals with EE, CF and MF was not able to promote motor activity changes. These data demonstrate that S. cordifolia has a pronounced antinociceptive activity against orofacial nociception. However, pharmacological and chemical studies are continuing in order to characterize the mechanism(s) responsible for this antinociceptive action and also to identify other active substances present in S. cordifolia.<br>A Sida cordifolia pertencente a família Malvaceae e gênero Sida L. com cerca de 250 espécies em todo mundo, tem sido utilizada na medicina popular como anti-inflamatória, antireumático e antipirético, laxante, diurético, analgésico e hipoglicemiante, antiviral, bactericida e antifúngica. O objetivo do presente estudo foi identificar a possível ação antinociceptiva do extrato etanólico (EE) e das frações clorofórmica (FC) e metanólica (FM) obtidas das folhas de Sida cordifolia, conhecida no Brasil como malva branca . As folhas de Sida cordifolia foram usadas para a preparação do extrato bruto e depois foi obtida frações a partir desse extrato. Os experimentos foram realizados com camundongos Swiss usando o glutamato e formalina como agentes de indução da nocicepção orofacial. No teste da formalina, todas as doses do EE, FC e FM significativamente reduziram o comportamento nociceptivo orofacial em ambas as fases do teste (p<0,001), as quais foram sensíveis a naloxona. A média percentual de redução para a primeira fase do teste da formalina foi 79,6% (EE), 78,4% (FC) e 65,6% (FM) e para a segunda fase 77,9% (EE), 69,7% (FC) e 81,1% (FM). No teste de nocicepção induzida por glutamanto, somente as FC e FM reduziram significativamente o comportamento nociceptivo orofacial com um percentual de inibição de 48,1% (100 mg/kg, FC), 56,1% (200 mg/kg, FC), 66,4% (400 mg/kg, FC), 48,2% (200 mg/kg, FM) e 60,1% (400 mg/kg, FM). O tratamento dos animais com EE, FC e FM não foi capaz de promover alterações na atividade motora. Esses resultados demonstraram que a S. cordifolia possui um pronunciado efeito sobre a nocicepção orofacial. No entanto, estudos químicos e farmacológicos são necessários a fim de caracterizar os mecanismos responsáveis por essa ação antinociceptiva, bem como identificar substâncias presentes dentro da S. cordifolia
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Bussioli, Icleia Boselli. "Influencia da disponibilidade de recursos oferecidos pela planta invasora Sida cordifolia L. (Malvaceae) sobre a estrutura da comunidade local de artropodes associados." [s.n.], 1997. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316098.

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Orientador: Maria Alice Garcia<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-23T00:02:52Z (GMT). No. of bitstreams: 1 Bussioli_IcleiaBoselli_M.pdf: 4830027 bytes, checksum: 8613264912f68a8d0dd821f6f68fdc64 (MD5) Previous issue date: 1997<br>Resumo: A fauna de artrópodes associada a uma população da planta invasora Sida cordifolia foi amostrada mensalmente, durante um ano, em Campinas, SP. As 154 espécies encontradas estão organizadas de acordo com estágio de desenvolvimento coletado, guilda, parte da planta atacada e frequência de ocorrência. Trinta e quatro espécies de fitófagos alimentam-se e/ou reproduzem-se a planta. Verificou-se como estas espécies, seus parasitóides e predadore respondem às variações da quantidade de recursos, medida em biomassa/planta e diversidade de recursos, registrando-se a presença ou ausência de órgãos reprodutivos. As guildas foram encontradas em frequências semelhantes em plantas vegetativas e maduras, porém, um indivíduo maduro pode sustentar um número maior de espécies. A riqueza de espécies também é maior para o conjunto de plantas maduras. A biomassa total disponível para colonização pelos artrópodes varia pouco durante o ano, mas no campo sempre existe uma fenofase predominante. A biomassa explica uma pequena proporção da variação no número de fitófagos encontrado por indivíduo, com exceção de um período, o outono, quando esta relação positiva é mais acentuada. Este período é caracterizado pela maior disponibilidade de recursos. Embora variando no tempo, à medida que aumenta a biomassa há um aumento na riqueza e densidade de fitófagos e entomófagos que utilizam a planta. Plantas maduras, além de tenderem a ser maiores, apresentam também maior diversidade de recursos e portanto nichos a serem ocupados. Análise comparativa de plantas com mesma diversidade de recursos mas com biomassa diferente demonstra que o tamanho tem um efeito relativamente pequeno sobre a densidade e riqueza de artrópodes. Por outro lado, a diversidade de recursos representada pela presença ou estágio de desenvolvimento de alguns órgãos da planta é limitante para a ocorrência de algumas espécies associadas a S. cordifolia, principalmente brocadores de ramo e de trutos. As diferenças encontradas entre plantas maduras e vegetativas desaparecem quando não consideramos as espécies associadas aos órgãos reprodutivos. Portanto, a contribuição deste último fator parece ser mais relevante para a variação na estrutura da comunidade observada entre plantas em diferentes fenofases e ao longo do ano. As espécies fitófagas oligófagas são consideradas como possíveis agentes de controle biológico, mas para outras regiões pois são atacadas por parasitóides e/ou se alimentam de espécies de plantas cultivadas na região<br>Abstract: The arthropod fauna associated to a population of the weed Sida cordifolia was surveyed monthly, during one year, in Campinas, SP, Brazil. The 154 species were sorted and analyzed according to life stage, guild, part of the plant attacked and frequency. Thirty four of phytophagous were recorded feeding and/or breeding on the plant. Were tested the response of phytophagous species, their parasitoids and predators to variation of plant biomass and resource diversity, by recording the presence or not of reproductive organs. The guilds are in similar frequencies in mature and vegetative plants, but mature individual plants support more species. The total species richness is also higher in these plants compared to vegetative ones. The total biomass available for colonizing arthropods varied very slightly during the year, but in the field, there is always one prevailing plant stage. Biomass explains a small proportion of the variation per plant. However, during the autumn the variation is better explained, probably because the effect of higher biomass reproductive organs. Although varying during the year, an increase in plant biomass is followed by increase in phytophagous and entomophagous density and composition. Mature plants tend to be bigger and, in addition, the higher resource diversity provides niches to be occupied. The comparison of plants with same resources, but differing biomass, show minor importance of plant size on arthropod composition and density. In contrast, the resource diversity provided by presence or development stage of some plant parts are required for the occurrence of some species associated to S. cordifolia, mainIy endophagous and fruit feeders. The observed differences between mature and vegetative plants disappear when are excluded the insects associated to reproductive organs. Thus, the resource diversity appears to be the mainly factor influencing the variation on the community structure observed along the year and in different plant stages. Some species are suggested as possible biological control agents in other regions than Campinas, because in this region they are heavily attacked by natural enemies or feed on cultivated plants<br>Mestrado<br>Mestre em Ciências Biológicas
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"Influencia da disponibilidade de recursos oferecidos pela planta invasora Sida cordifolia L. (Malvaceae) sobre a estrutura da comunidade local de artropodes associados." Tese, Biblioteca Digital da Unicamp, 1997. http://libdigi.unicamp.br/document/?code=vtls000120386.

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Books on the topic "Sida cordifolia"

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Bruneau, William. A User's Guide to Sida acuta, Sida cordifolia, and Sida rhombifolia : : How to Grow, Harvest, and Make Medicinals from the World's Best Herbal ... Superior Fiber, Grow Them with Your Tomatoes. CreateSpace Independent Publishing Platform, 2018.

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Book chapters on the topic "Sida cordifolia"

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Dev, Sukh. "Sida cordifolia." In Prime Ayurvedic Plant Drugs. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22075-3_92.

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Khare, C. P. "Sida cordifolia Linn." In Indian Medicinal Plants. Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1494.

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Azimova, Shakhnoza S., and Anna I. Glushenkova. "Sida cordifolia L." In Lipids, Lipophilic Components and Essential Oils from Plant Sources. Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_2063.

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Akbar, Shahid. "Sida cordifolia L. (Malvaceae)." In Handbook of 200 Medicinal Plants. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-16807-0_171.

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Dalar, Abdullah, and Muzaffer Mukemre. "Current Medicinal Plants in the Treatment of Parkinson’s Disease." In Brain Health and Medicinal Plants. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359241.8.

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This chapter presents botanical and chemical properties, and therapeutic potential in neurological diseases of medicinal plants currently utilized in Parkinson’s disease. Parkinson’s disease is the second most common neurological brain disease that accompanied by movement disorders. Currently used modern medicines such as levodopa have serious side effects and therefore safe, and effective medicines from natural sources with minimized side effects are necessary for the management and/or treatment of Parkinson’s disease. Natural sources especially plant-based materials are rich in antioxidant compounds and therefore, they can be examined for the discovery of new drugs that can be used in the treatment of Parkinson’s disease. Within this chapter 18 common medicinal plants including Centella asiatica, Panax ginseng, Carthamus tinctorius, Mucuna pruriens, Gingko biloba, Hypericum perforatum, Ocimum santam, Hibiscus asper, Sida cordifolia, Tinospora cordifolia, Peganum harmala, Paeonia lactiflora, Bacopa monnieri, Polygola tenuifolia, Polygonum cuspidatum, Withania somnifera, Camellia sinensis, and Curcuma longa were reviewed. All medicinal plants reported in this chapter were found to have a common mode of action, namely stabilizing redox and stimulating mitochondrial function. It was determined that the chemical compounds of the plant species mentioned in this chapter have significant anti-Parkinson performance and therefore can be examined in clinical Parkinson’s studies which targeted for the discovery of natural-based effective and safe anti-Parkinson drugs.
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Ahmed, Hassan, Abdul Shukor Juraimi, Mallappa Kumara Swamy, et al. "Botany, Chemistry, and Pharmaceutical Significance of Sida cordifolia: A Traditional Medicinal Plant." In Anticancer plants: Properties and Application. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8548-2_22.

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Mande, Annie, Narender Malothu, and Tata Prasanna Kumari. "Evaluation of Neuroprotective Activity of Sida Cordifolia Against β-AMYLOID Protein Induced Loss of Cognitive Functions in Swiss Albino Mice." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00673.

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Neurodegenerative disorders are most prevalent in older patients. The plant, Sida Cordifolia is a perennial shrub which belongs to the family Malvaceae. S. Cordifolia was proved to possess analgesic, hypoglycaemic, hepatoprotective, and antioxidant activities. The main objective of the present work was to screen the neuroprotective potential of the whole plant S. Cordifolia. The preliminary phytochemical and the acute toxicity evaluation of the extract were done. The neuroprotective potential of the extract was evaluated with the help of Y- maze, water maze and step-down inhibitory avoidance test. The biochemical parameters of the isolated brain serum samples of the treated groups were measured. The animals treated with S. Cordifolia has improved short term and long-term memories, escape latencies, exploratory behaviour, and percentage alterations. The group treated with S. Cordifolia plant was proved to have neuroprotective activity by showing improvement in different parameters in above stated models and enhanced levels of different neurotransmitters. Further studies are required to establish the clinical significance of this plant as a neuroprotective agent.
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8

Kumar, Suman, Susankar Kushari, Himangshu Sarma, and Damiki Laloo. "Exploring the Traditional System of Medicine With Special Emphasis on the Indigenous Practice of Herbal Remedy by the Tribals of North-East India." In Practice and Re-Emergence of Herbal Medicine. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815080414123010003.

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The tribal people of India consider North-East India to be a hotspot. It contains eight states: Arunachal Pradesh, Assam, Manipur, Mizoram, Meghalaya, Nagaland, Tripura and Sikkim, and it borders international boundaries with Bhutan, Tibet, China, Burma and Bangladesh. The Indo-Burma biodiversity hotspot, which is home to a broad spectrum of unusual flora, fauna and microorganisms, is located in the Northeast Region. The region has the evergreen forest of the Brahmaputra River valley, wide leaf forest, dense bamboo and pine forest and the world's wettest location (Cherrapunji and Mawsynram), all of which help to maintain the region's unique biodiversity. North East region is the inhabitant of more than 145 significant tribal communities with the most dominating primitive societies, including the Abor, Mishing, Rabha, Khasi, Kuki, Naga, Meitei, Apatani, etc. Most of these communities are culturally and linguistically diverse. The NER's tribal population is literate compared to other parts of the country, and it's worth noting that the literacy rates in Mizoram, Meghalaya, Nagaland, Sikkim and Manipur are all higher than the national average. Despite their high literacy rate, India's North-Eastern states continue to have poor transportation, power and medical services. The healthcare system is in bad shape, with only a few hospitals and nursing homes. As a result, the people residing in this area rely exclusively on a traditional system of medicines made by traditional healers from plants, animals and mineral resources. It was stated that medicinal herbs are prepared using traditional methods, such as maceration, decoction, and infusion, either alone or in combination with other plants. The key species of medicinal plants often employed by the traditional healers of the region are Acorus calamus, Aegle marmelos, Asparagus racemosus, Averrhoa carambola, Bryophyllum calycinum, Costus speciosus, Euphorbia neriifolia, Justicia adhatoda, Melia azadarachta, Plumeria acutifolia, Sida cordifolia, Sida rhombifolia and Swertia chirata. This extensive work will aid the researcher in locating previously unknown medicinal plants in order to build a new therapeutic method for isolating new chemical entities that are safe, pharmacologically active, and cost-effective.
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Ashok, Purnima, Arulmozhi S., B. P. Bhaskara, R. Rajendran, and B. G. Desai. "Evaluation of Food Intake Inhibitory Activity of Aqueous Extract of Sida cordifolia (AESC) and Alcoholic Extract of Withania somnifera (AEWS)." In Pharmaceutical Research - Recent Advances and Trends Vol. 4. B P International, 2024. http://dx.doi.org/10.9734/bpi/prrat/v4/1145.

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10

Singh, Sippy, and Durgesh Singh. "Himalayan Herbs: A Promising Medication Source for Neurodegenerative Diseases." In Bioactive Phytochemicals from Himalayas: A Phytotherapeutic Approach. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815123289123010006.

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The Himalayas have been known for their plant diversity, as they are rich in nearly 8000 vascular plant species, which include approximately 1748 plants containing medicinal properties. Ayurveda, a branch of traditional medication focuses on substances of natural origin like plants, their parts, minerals, and animal parts either alone or in combination. With the advancement in Science and Technology, there has been an increase in the understanding of molecular mechanisms behind the origin of diseases. Recently, the roles of several bioactive molecules present in natural sources in blocking or treating diseases have also become increasingly clear. Since the Himalayas are rich herbal treasures; therefore the plant diversity, as well as their medicinal properties have been widely explored. Progressive loss of nerve cells/neurons in terms of structure and function is termed neurodegeneration. Selective loss of neurons leads to nervous disorders referred to as Neurodegenerative disorders/diseases, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc., are some of the major health issues suffered by individuals in the current situation. Plant-derived bioactive molecules or phytomedicines have been in practice for many years and have been found to be effective in managing/treating these disorders. This chapter aims at highlighting some of the Himalayan herbs, which exhibit a promising role in managing neurodegenerative diseases. For example, Acorus calamus is well known for its brain rejuvenating ability. It has been found that A. calamus possesses neuroprotective activity against stroke. Asparagus racemosus, known for its anti-aging activity, has been observed to protect the brain from oxidative damage, thereby preventing neurodegenerative diseases. Calotropis procera is ethnomedicinally used to treat mental disorders. Sida cordifolia, another perennial shrub found in the Himalayan region used for treating many ailments related to the respiratory system is also used for treating patients suffering from Parkinson’s disease. There are many more plants found in the Himalayan region, which have the potential for treating brainrelated disorders. The rising cases of neurodegenerative disorders need a better understanding of plants rich in neuroprotective phytochemicals. Plants are one of the promising medication sources with the least side effects, which will help in providing an ethnopharmacological aspect and managing/treating neurodegenerative disorders.
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