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1

Schuitemaker, Hanneke, and Frank Miedema. "Comment on Mosier and Sieburg." Immunology Today 16, no. 1 (January 1995): 50–51. http://dx.doi.org/10.1016/0167-5699(95)80071-9.

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2

Bonifer, Constanze. "In memoriam: Christa Muller-Sieburg (1952–2013)." Experimental Hematology 41, no. 4 (April 2013): 323–24. http://dx.doi.org/10.1016/j.exphem.2013.03.001.

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3

Wittenbruch, Wilhelm. "Manfred Sieburg (2009): Der Erziehungskonsens an katholischen Gymnasien. Erschienen im Eigenverlag: Wachtberg-Fritzdorf. 225 Seiten." Vierteljahrsschrift für wissenschaftliche Pädagogik 86, no. 3 (July 4, 2010): 431–35. http://dx.doi.org/10.30965/25890581-08603014.

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4

Dziergwa, Roman. "Polen und das deutsche Sachbuch der Zwischenkriegszeit. Zu einigen Aspekten der Polenbücher von Friedrich Sieburg, Elga Kern und Heinrich Koitz." Studia Germanica Posnaniensia 25 (October 29, 2018): 69–80. http://dx.doi.org/10.14746/sgp.1999.25.06.

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5

Fijałkiewicz, Michał. "Glesener, Jeanne E. / Roelens, Nathalie / Sieburg, Heinz (Hg.) (2017): Das Paradigma der Interkulturalität. Themen und Positionen in europäischen Literaturwissenschaften. Bielefeld: transcript. 200 S." Studia Germanica Gedanensia, no. 41 (November 23, 2019): 359–61. http://dx.doi.org/10.26881/sgg.2019.41.26.

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6

Kellermeier-Rehbein, Birte. "Sieburg, Heinz/Solms, Hans-Joachim (Eds.) (2017): Das Deutsche als plurizentrische Sprache. Ansprüche - Ergebnisse - Perspektiven (= Zeitschrift für deutsche Philologie 136). Berlin: Erich Schmidt Verlag. 224 S." Sociolinguistica 34, no. 1 (November 25, 2020): 251–53. http://dx.doi.org/10.1515/soci-2020-0015.

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7

Treichel, Eckhardt. "Ewald Grothe (Hrsg.), Die Abgeordneten der kurhessischen Ständeversammlungen 1830–1866. Hrsg. unter Mitarb. v. Armin Sieburg. (Politische und parlamentarische Geschichte des Landes Hessen, Bd. 43.) Marburg, Historische Kommission für Hessen 2016." Historische Zeitschrift 306, no. 1 (February 6, 2018): 233–34. http://dx.doi.org/10.1515/hzhz-2018-1052.

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8

Kleineidam, Ulf. "Richtige Siebung sichert konstantes Beschichtungsergebnis." JOT Journal für Oberflächentechnik 46, no. 8 (August 2006): 24–26. http://dx.doi.org/10.1007/bf03241273.

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9

Kleineidam, Ulf. "Richtige Siebung sichert konstantes Beschichtungsergebnis." JOT Journal für Oberflächentechnik 45, no. 8 (August 2005): 24–26. http://dx.doi.org/10.1007/bf03242995.

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10

Salmen, Saleh H., Nadiah Matluq Alkammash, Tahani Awad Alahmadi, and Sulaiman Ali Alharbi. "Characterization and Antibacterial Activity of Silver Nanoparticles Biosynthesized Using Leaves Extract of Artemisia sieberi and Calotropis procera." Revista de Chimie 72, no. 2 (May 7, 2021): 76–82. http://dx.doi.org/10.37358/rc.21.2.8421.

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The prevalence of antibiotic-resistant bacteria has increased recently leading to the need for novel, natural antibacterial agents such as plant-synthesized silver nanoparticles. Such synthesis is safe, cheap, rapid, non-toxic and environmentally friendly. In this study, characterization of biosynthesized silver nanoparticles from extracts of A. sieberi and C. procera was carried out using transmission electron microscopy, fourier transform infrared and energy dispersive x-ray analysis. Spherical nanoparticles with an average size was ~10 nm for A. sieberi and ~14 nm for C. procera were synthesised; synthesis was most effective using A. sieberi. Antibacterial activity of silver nanoparticles was carried out using the agar-diffusion method and by determination of the minimum inhibitory concentration. Biosynthesized silver nanoparticles showed antibacterial activity against Staphylococcus aureus, MRSA, Salmonella typhimurium and Escherichia coli, with silver nanoparticles extracts from A. sieberi being the most antibacterial.
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11

Spötter, Christian, Frederik Elskamp, Manuel Hennig, Ulrich Teipel, Alfred P. Weber, and Harald Kruggel-Emden. "Trennkurven in Siebung und Gegenstromsichtung bei geringen Gutbeladungen." Chemie Ingenieur Technik 89, no. 12 (September 26, 2017): 1726–38. http://dx.doi.org/10.1002/cite.201600156.

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12

Marosi, Ernő. "János Végh ist siebzig." Acta Historiae Artium 47, no. 1 (March 1, 2006): 5–9. http://dx.doi.org/10.1556/ahista.47.2006.1-4.1.

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13

Klauer, Karl Christoph. "Siebzig Jahre Psychologische Rundschau." Psychologische Rundschau 70, no. 1 (January 2019): 1–3. http://dx.doi.org/10.1026/0033-3042/a000428.

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14

Schimitschek, E. "Moriz Seitner, siebzig Jahre." Zeitschrift für Angewandte Entomologie 19, no. 4 (August 26, 2009): 625–27. http://dx.doi.org/10.1111/j.1439-0418.1932.tb00329.x.

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15

Körtner, Ulrich H. J. "Siebzig Jahre nach Barmen." Zeitschrift für Evangelische Ethik 48, no. 1 (February 1, 2004): 2–6. http://dx.doi.org/10.14315/zee-2004-0103.

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16

Tyquiengco, Marina, and Monika Siebert. "Are Indians in America's DNA?" Contemporaneity: Historical Presence in Visual Culture 8 (October 30, 2019): 80–97. http://dx.doi.org/10.5195/contemp.2019.288.

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A conversation between Dr. Monika Siebert and Marina Tyquiengco on: Americans National Museum of the American Indian January 18, 2018–2022 Washington, D.C. Monika Siebert, Indians Playing Indian: Multiculturalism and Contemporary Indigenous Art in North America. Tuscaloosa: University of Alabama Press, 2015.
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17

Wardlaw, TJ, and C. Palzer. "Regeneration of Eucalyptus Species in an Eastern Tasmanian Coastal Forest in the Presence of Phytophthora cinnamomi." Australian Journal of Botany 36, no. 2 (1988): 205. http://dx.doi.org/10.1071/bt9880205.

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The composition of Eucalyptus regeneration following Phytophthora cinnamomi infestation in an E. sieberi open, shrubby forest is examined. Surveys made to determine the composition of the original stand show that E. sieberi dominated all sites examined in the study area. Regeneration of Eucalyptus spp. from both aerial sowing (in a logged area) and natural seed fall (in an unlogged area) has resulted in increased species heterogeneity. Even in the presence of P. cinnamomi, the susceptible E. sieberi and E. obliqua seedling regenerations have significantly higher relative height growth rates than the field-resistant species E. globulus, E. ovata and E. viminalis on all sites examined.
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18

Karimipoor, Zahra, Anahita Rashtian, Masoume Amirkhani, and Somayeh Ghasemi. "The Effect of Grazing Intensity on Vegetation Coverage and Nitrogen Mineralization Kinetics of Steppe Rangelands of Iran (Case Study: Nodoushan Rangelands, Yazd, Iran)." Sustainability 13, no. 15 (July 27, 2021): 8392. http://dx.doi.org/10.3390/su13158392.

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Livestock grazing can affect the cycling of nutritional elements in soil by making changes to the vegetation coverage. This study aimed to investigate the effect of rangeland exploitation on vegetation coverage and nitrogen kinetics. To this end, three experimental sites of light, moderate, and heavy grazing in Nodoushan rangelands of Yazd province were selected. The vegetation properties were then measured through systematic random sampling method and three to five bases along the transect were sampled from the current year growth of the dominant plants in the region. The soil samples were collected from 0–15 cm depth in five replications and mixed together to obtain a single composite soil sample on each site. In the first stage, nitrogen (N), carbon (C), C/N, cellulose, hemicellulose, and lignin of the sampled plant as well as nitrogen, carbon, lime, soil texture, saturation moisture percentage, pH, and electrical conductivity (EC) of the soil were measured. As the soil properties did not differ for light and moderate grazing soils, different treatments were conducted on the dominant species of light and heavy grazing sites with 1% organic carbon added to the rangeland soil. Nitrogen mineralization treatments were selected based on vegetation changes that, with increasing livestock grazing intensity, changed the predominance of plant composition from Artemisia sieberi and steppe to percentage Artemisia sieberi and Peganum harmala. The treatments included control, 100% Artemisia sieberi, 75% Artemisia sieberi and 25% Peganum harmala, 50% Artemisia sieberi and 50% Peganum harmala, 25% Artemisia sieberi and 75% Peganum harmala, and 100% Peganum harmala. The soil samples were incubated for pure nitrogen mineralization in three replications of 3 months. The results of nitrogen mineralization revealed that the immobilization of the treated soil with higher Artemisia sieberi and lower Peganum harmala was done at a more rapid rate during the first week. The immobilization was slowly reduced by the third week and then followed a growing rate. Overall, the results show that an increase in grazing intensity was associated with a change in vegetation coverage toward Peganum harmala species, the biochemical characteristics of which elevated the levels of pure nitrogen mineralization in soil.
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19

Saraf, Isha, Alka Choudhary, Ram Jee Sharma, Karthik Dandi, Karen J. Marsh, William J. Foley, and Inder Pal Singh. "Extraction of Pinocembrin from Leaves of Different Species of Eucalyptus and its Quantitative Analysis by qNMR and HPTLC." Natural Product Communications 10, no. 3 (March 2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000301.

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Pinocembrin, a flavanone with a variety of biological activities was isolated from Eucalyptus sieberi leaves and quantified in several other Eucalyptus species using qNMR and HPTLC densitometry. The effect of different extraction procedures on the extraction of the compound from Eucalyptus sieberi was also studied. The methods were validated in terms of selectivity, specificity, linearity, recovery, precision and repeatability.
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20

Sieber, V. "Dr. Sieber replies." Burns 22, no. 5 (August 1996): 424. http://dx.doi.org/10.1016/0305-4179(96)90006-6.

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21

Ottenberg, Simon, and Roy Sieber. "To Roy Sieber." African Arts 19, no. 4 (August 1986): 76. http://dx.doi.org/10.2307/3336298.

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22

Sieber, Roy. "Remarks by Sieber." African Arts 23, no. 4 (October 1990): 90. http://dx.doi.org/10.2307/3336955.

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23

Krivosejev, Vladimir. "Valjevo’s medical doctor Jovan Siber and pharmacist Klaudije Prikelmajer: A historical illustration of the role of immigrants from Slavonia to the development of health care in Serbia." Srpski arhiv za celokupno lekarstvo 145, no. 7-8 (2017): 421–27. http://dx.doi.org/10.2298/sarh170222101k.

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In a short period of the late 1860s, three significant new institutions were founded in Valjevo: the hospital (1867), the grammar school (1869) and the pharmacy (1870). In the early stages of development of all three institutions, a big role was played by immigrants from Slavonia: medical doctor Jovan Sieber, pharmacist Klaudije Prikelmajer, and professor Djuro Kozarac. This paper aims to clarify the connections between these individuals that caused their relocation from the territories of the Habsburg Monarchy to Serbia and Valjevo, as well as to resolve the confusion caused by imprecise family memories and written chronicles that have been collected. Moreover, this paper additionally focuses on the origins of the Sieber family, which included Jovan Sieber, and the later arrival of other members of the family to Valjevo. Another member of the family was Jovan?s nephew Dr. Stevan Sieber, father of Dr. Djordje Sieber, who went on to become a general in the Medical Corps of the Royal Yugoslav Army.
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24

Nahrevanian, Hossein, Bayram Sheykhkanlooye Milan, Masoud Kazemi, Reza Hajhosseini, Soudeh Soleymani Mashhadi, and Shahab Nahrevanian. "Antimalarial Effects of Iranian Flora Artemisia sieberi on Plasmodium berghei In Vivo in Mice and Phytochemistry Analysis of Its Herbal Extracts." Malaria Research and Treatment 2012 (January 23, 2012): 1–8. http://dx.doi.org/10.1155/2012/727032.

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The aim of this study is pharmacochemistry of Iranian flora Artemisia sieberi and its antimalarial effects on Plasmodium berghei in vivo. This is the first application of A. sieberi for treatment of murine malaria. A. sieberi were collected at flowering stage from the Khorassan and Semnan provinces of Iran; the aerial parts were air-dried at room temperature and then powdered. The powder was macerated in methanol, filtered with Bokhner hopper and solvent was separated in rotary evaporator. Total herbal extract was subsequently processed for ether and chloroform extracts preparation. The toxicity of herbal extract was assessed on naive NMRI mice with high, average and low doses; then pathophysiological signs were assessed. Finally, the antimalarial efficacy was investigated on two groups of Plasmodium berghei infected mice. Percentage of parasitaemia and pathophysiology were also evaluated. The results of this assessment showed no toxicity even by high concentration of herbal extract. A significant reduction in percentage of parasitaemia was observed; no alterations of hepatosplenomegaly and body weight were indicated in study group. A. sieberi extracts showed antimalarial effects against murine malaria with some efficacies on reducing pathophysiology. However, there is requirement to find the major component of this herbal extract by further studies.
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25

Schirren, C. "A. Siebert: Recht und Medizin." Andrologia 16, no. 3 (April 24, 2009): 227. http://dx.doi.org/10.1111/j.1439-0272.1984.tb00270.x.

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26

Abd El-Ghani, Monier M., Ashraf S. A. El-Sayed, Ahmed Moubarak, Rabab Rashad, Hala Nosier, and Adel Khattab. "Biosystematic Study on Some Egyptian Species of Astragalus L. (Fabaceae)." Agriculture 11, no. 2 (February 4, 2021): 125. http://dx.doi.org/10.3390/agriculture11020125.

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Astragalus L. is one of the largest angiosperm complex genera that belongs to the family Fabaceae, subfamily Papilionoideae or Faboideae under the subtribe Astragalinae of the tribe Galegeae. The current study includes the whole plant morphology, DNA barcode (ITS2), and molecular marker (SCoT). Ten taxa representing four species of Astragalus were collected from different localities in Egypt during the period from February 2018 to May 2019. Morphologically, identification and classification of collected Astragalus plants occurred by utilizing the light microscope, regarding the taxonomic revisions of the reference collected Astragalus specimens in other Egyptian Herbaria. For molecular validation, ten SCoT primers were used in this study, producing a unique banding pattern to differentiate between ten samples of Astragalus taxa which generated 212 DNA fragments with an average of 12.2 bands per 10 Astragalus samples, with 8 to 37 fragments per primer. The 212 fragments amplified were distributed as 2 monomorphic bands, 27 polymorphic without unique bands, 183 unique bands (210 Polymorphic with unique bands), and ITS2 gene sequence was showed as the optimal barcode for identifying Astragalus L. using BLAST searched on NCBI database, and afterward, analyzing the chromatogram for ITS region, 10 samples have been identified as two samples representing A. hauarensis, four samples representing A. sieberi, three samples representing A. spinosus and one sample representing A. vogelii. Based on the ITS barcode, A. hauarensis RMG1, A. hauarensis RMG2, A. sieberi RMG1, A. sieberi RMG2, A. sieberi RMG3, A. sieberi RMG4, A. spinosus RMG1, A. spinosus RMG2, A. spinosus RMG3, A. vogelii RMG were deposited into GenBank with accession # MT367587.1, MT367591.1, MT367593.1, MT367585.1, MT367586.1, MT367588.1, MT160347.1, MT367590.1, MT367589.1, MT367592.1, respectively. These results indicated the efficiency of SCoT markers and ITS2 region in identifying and determining genetic relationships between Astragalus species.
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27

Grünig, Christoph R., Valentin Queloz, Thomas N. Sieber, and Ottmar Holdenrieder. "Dark septate endophytes (DSE) of the Phialocephala fortinii s.l. – Acephala applanata species complex in tree roots: classification, population biology, and ecology." Botany 86, no. 12 (December 2008): 1355–69. http://dx.doi.org/10.1139/b08-108.

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Dark septate endophytes (DSE), a diverse group of ascomycetes, are dominant root colonizers in many ecosystems. The most frequent DSE in natural forest ecosystems in the Northern hemisphere belong to the Phialocephala fortinii s.l. – Acephala applanata species complex (PAC). Recently, species rank was assigned to seven cryptic species (CSP) of P. fortinii s.l.: Phialocephala fortinii s. str. C.J.K. Wang & H.E. Wilcox, Phialocephala europaea C.R. Grünig et T.N. Sieber, Phialocephala helvetica C.R. Grünig et T.N. Sieber, Phialocephala letzii C.R. Grünig et T.N. Sieber, Phialocephala subalpina C.R. Grünig et T.N. Sieber, Phialocephala turiciensis C.R. Grünig et T.N. Sieber, and Phialocephala uotolensis C.R. Grünig et T.N. Sieber. PAC species occur on all parts of the root system of trees, from mycorrhizal root tips to the stem base. Up to 80% of fine roots in forest stands can be colonized by them, and up to eight species occur sympatrically. The present work is a mixture of review and reconsideration of published work in the light of the subdivision of P. fortinii s.l. into several species. We review the current knowledge related to taxonomy, geographical distribution, population biology, and ecology of PAC species. We identified strains of P. fortinii s.l. from previously published studies to species level. The reassessment of earlier studies indicates that PAC species behave in a versatile manner along the mutualism-parasitism continuum and lifestyle designation is complicated by the use of different experimental systems. Finally we define the most promising research areas, which will contribute to elucidate the ecological role of root endophytes in general and PAC species in particular.
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28

Mitrović, Dejan, Mirjana Ivanović, Milan Vidaković, and Zoran Budimac. "The Siebog multiagent middleware." Knowledge-Based Systems 103 (July 2016): 56–59. http://dx.doi.org/10.1016/j.knosys.2016.03.017.

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29

Ross, Doran H., and Roy Sieber. "Interview with Roy Sieber." African Arts 25, no. 4 (October 1992): 36. http://dx.doi.org/10.2307/3336966.

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30

KARL, ROBERT D. "Paul Eugene Sieber, M.D." Radiology 164, no. 2 (August 1987): 587. http://dx.doi.org/10.1148/radiology.164.2.587-b.

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31

Link, Fabian, and Mark W. Hornburg. "“He Who Owns the Trifels, Owns the Reich”: Nazi Medievalism and the Creation of the Volksgemeinschaft in the Palatinate." Central European History 49, no. 2 (June 2016): 208–39. http://dx.doi.org/10.1017/s0008938916000352.

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AbstractThis article analyzes the interplay between Nazi cultural politics and regional identity in the Palatinate region of Germany through the lens of the Ludwig Siebert program. Created by Bavarian Minister-President Ludwig Siebert in the early 1930s to stimulate the regional construction industry, this program involved the conservation of medieval castles and ruins in Bavaria and the Palatinate. The renovation of these monuments, which had been central to the cultural memory and identity of Pfälzers since at least the nineteenth century, proved to be effective in mobilizing the local populace for Siebert's aims and, consequently, for the goals of the Nazi regime. Because its melding of cultural politics and regional identity helped to stabilize the regime in the Palatinate during its early years, the Siebert program provides a particularly illustrative microhistorical case study of the Nazi regime's mechanisms for creating the Volksgemeinschaft in the provinces. By focusing on the Palatinate town of Annweiler, which sits at the foot of the storied Trifels castle, a favored renovation project of Siebert's, this article offers a closely observed demonstration of these mechanisms at work.
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32

Rackwitz, Martin. "Siebers and Zagratzki (eds.), Deutsche Schottlandbilder." Scottish Historical Review 81, no. 1 (April 2002): 154–55. http://dx.doi.org/10.3366/shr.2002.81.1.154.

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33

Jennings, Michael W. "Re: Richard Sieburth on Walter Benjamin." Assemblage, no. 7 (October 1988): 118. http://dx.doi.org/10.2307/3171081.

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34

Verotta, Luisella, Marco Tatò, Nadia A. El-Sebakhy, and Soad M. Toaima. "Cycloartane triterpene glycosides from Astragalus sieberi." Phytochemistry 48, no. 8 (August 1998): 1403–9. http://dx.doi.org/10.1016/s0031-9422(98)00042-9.

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35

Phelan, James. "The Ethics of Criticism. Tobin Siebers." Modern Philology 87, no. 4 (May 1990): 435–38. http://dx.doi.org/10.1086/391816.

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36

Mohamed, Tarik A., Mohamed-Elamir F. Hegazy, Abeer A. Abd El Aty, Hazem A. Ghabbour, Mansour S. Alsaid, Abdelaaty A. Shahat, and Paul W. Paré. "Antimicrobial sesquiterpene lactones from Artemisia sieberi." Journal of Asian Natural Products Research 19, no. 11 (March 31, 2017): 1093–101. http://dx.doi.org/10.1080/10286020.2017.1302939.

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37

Weyerstahl, Peter, Sabina Schneider, Helga Marschall, and Abdolhossein Rustaiyan. "The essential oil ofArtemisia sieberi Bess." Flavour and Fragrance Journal 8, no. 3 (May 1993): 139–45. http://dx.doi.org/10.1002/ffj.2730080304.

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38

Traas, Deborah Vaniderstine. "The Romantic Fantastic by Tobin Siebers." L'Esprit Créateur 28, no. 3 (1988): 89. http://dx.doi.org/10.1353/esp.1988.0054.

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39

Raskov, D. E. "Who was Nikolai Sieber? Contexts of intellectual biography." Voprosy Ekonomiki, no. 4 (April 28, 2018): 111–28. http://dx.doi.org/10.32609/0042-8736-2018-4-111-128.

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The article deals with the rethinking of the contexts of intellectual biography of Nikolai Ivanovich Sieber (1844-1888) known as a Russian Marxist and the classical political economist. Three such contexts of collective practices, which give us broader understanding of his role and place are in the focus of the paper: university work and life, scientific travels abroad and the relationships and networks around publishing. On the base of secondary literature and new archival sources the author reveals the meaning of these institutions reconstructing the networks and the circle of Sieber. The author shows that Sieber had a large and diverse network in scientific and publishing activities, but as a representative of Russian cosmopolitan intellectual elite could not be judged in too narrow terms of national or revolutionary movements.
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40

Ferreux, Julie, Alice do Carmo Precci Lopes, Wolfgang Müller, Sabine Robra, and Anke Bockreis. "Bestimmung und Abtrennung des Fremdstoffgehaltes von Bioabfällen mittels Siebung und Windsichtung." Österreichische Wasser- und Abfallwirtschaft 72, no. 1-2 (November 8, 2019): 61–67. http://dx.doi.org/10.1007/s00506-019-00630-2.

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Zusammenfassung Kunststofffolien im Bioabfall führen zu Herausforderungen für Bioabfallbehandlungsanlagen, da sie trotz Aufbereitung in den fertigen Kompost gelangen. Anlässlich der neuen Grenzwerte des RAL-Gütezeichens wurde die Anwendung eines Stern- und Trommelsiebs sowie eines Querstrom-Windsichters in der Voraufbereitung von zwei Bioabfallbehandlungsanlagen in Deutschland untersucht. Untersucht wurde die Effizienz der Kunststofffolienabtrennung und die Transferraten der Biogaserträge in die entstehenden Fraktionen. Dafür wurden Proben aus großtechnischen Versuchen gezogen, händisch sortiert und alle Fremdstoffe gewaschen und getrocknet. Anschließend wurde das Biogaspotenzial mit einem automatisierten Batch-Gärtest gemessen. Die Ergebnisse weisen einen Verlust von ca. 30 % an Biogas aus, der durch die Abtrennung der anhaftenden organischen Substanz während der Aufbereitung bedingt ist. Dem gegenüber steht eine Abtrennung von ca. 90 % der Kunststofffolien, was ein Erreichen der Grenzwerte des RAL-Gütezeichens potenziell ermöglicht.
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41

Wendler, J., M. Sieburg, E. Movshovich, N. Damann, and F. Behrens. "AB0847 HIGH TOLERABILITY OF USTEKINUMAB IN THE TREATMENT OF PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS – RESULTS OF THE NON-INTERVENTIONAL STUDY SUSTAIN." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1730–31. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4530.

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Background:Several biologics available for the treatment of psoriatic arthritis (PsA) have demonstrated effectiveness. A major aim of the treating physician is to find the safest treatment for his patients.Objectives:In this work we analyzed the safety of ustekinumab in the treatment of PsA in a real-world setting.Methods:The SUSTAIN study is a prospective, multi-center non-interventional study in Germany designed to evaluate long term effectiveness and safety, quality of life, and other patient reported outcomes in patients with active PsA under treatment with ustekinumab in routine clinical care over the course of 160 weeks. Treatment with ustekinumab is according to the label recommendations. In the third interim analysis we evaluated the data of 336 included patients till week 112.Safety was evaluated based on the following parameters: numbers of adverse events (AEs), serious AEs (SAEs), and physicians’ / patients’ assessment of tolerability of treatment with ustekinumab. AEs are either reported by the subject voluntarily or are obtained by means of subject interviews at study visits. AE definitions, attribution rules, and severity criteria were pre-specified in the study plan. All AEs / SAEs were recorded and described including information on date of onset, seriousness, severity, outcome, action taken, and relationship to treatment as evaluated by the physician. All AEs were followed to satisfactory resolution or a clinically stable endpoint.Results:For this analysis 336 patients (57% women) at 75 centers were included. Data for key study visits were obtained for the following numbers of patients: 310 patients at week 4, 237 patients at week 40, 160 patients at week 76, and 108 patients at week 112. A total of 88 SAEs (9.0% of all reported AEs) have been documented through the data cut-off date including SAEs of the categories musculoskeletal and connective tissue disorders (n=21, 6.3% of all reported AEs), nervous system disorders (n=8, 2.4%), infections and infestations (n=9, 2.7%), neoplasms (n=4, 1.2%), cardiac disorders (n= 7, 2.1%). Overall, 14 (1.4% of all reported AEs) of the 88 SAEs were assessed as related to ustekinumab (Table 1). AEs and SAEs lead to permanent discontinuation of treatment with ustekinumab in 119 and 11 patients, respectively. The vast majority of AEs leading to treatment discontinuation amount to ineffective drug or drug effect decrease (n=84) and psoriatic arthropathy (n=16). The most frequent SAE leading to discontinuation was psoriatic arthropathy (n=4). Tolerability of therapy with ustekinumab was assessed as “very good” or “good” by 98.1% of the treating physicians after 76 weeks and by 100% after 112 weeks (Figure 1 A). Tolerability was assessed as “very good” or “good” by 98.7% of patients at week 76 and by 100% at week 112 (Figure 1 B). Overall, the safety profile of ustekinumab in this population of psoriatic arthritis patients through week 112 was generally consistent with that demonstrated in earlier studies.Table 1.Summary of adverse events in all patients (N=336)n (%)No. / % of patients at risk336 (100.0) with adverse event (AE)269 (80.1) with AE related to Ustekinumab1188 (56.0) with AE related to MTX195 (28.3) with serious adverse event (SAE)52 (15.5) with SAE related to Ustekinumab111 (3.3) with SAE related to MTX13 (0.9)No. / % of events all AE980 (100.0) AE related to Ustekinumab1383 (39.1) AE related to MTX1156 (15.9) SAE88 (9.0) SAE related to Ustekinumab114 (1.4) SAE related to MTX13 (0.3)1‘related’ events are events with missing, possible, likely or very likely causalityFigure 1.Global Assessments of tolerabilityConclusion:In this interim analysis of safety data from the non-interventional SUSTAIN study, ustekinumab was highly tolerated in the treatment of patients with active PsA in routine clinical practice through up to 112 weeks.Disclosure of Interests:Joerg Wendler Consultant of: Janssen, AbbVie, Sanofi, Speakers bureau: Roche, Chugai, Janssen, AbbVie, Novartis, Maren Sieburg: None declared, Evgenia Movshovich: None declared, Nils Damann: None declared, Frank Behrens Grant/research support from: Pfizer, Janssen, Chugai, Celgene, Lilly and Roche, Consultant of: Pfizer, AbbVie, Sanofi, Lilly, Novartis, Genzyme, Boehringer, Janssen, MSD, Celgene, Roche and Chugai
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42

Behrens, F., G. R. Burmester, M. Feuchtenberger, H. Kellner, C. Kühne, A. Liebhaber, M. Sieburg, et al. "FRI0054 CHANGES IN DEPRESSIVE SYMPTOMS IN RHEUMATOID ARTHRITIS (RA) PATIENTS DURING TOCILIZUMAB (TCZ) THERAPY: THE GERMAN NONINTERVENTIONAL ARATA STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 603.2–603. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4535.

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Background:Depression is a common comorbidity in patients with RA and influences perception of disease activity and quality of life. We have previously reported that mean depression scores improved during TCZ therapy in conjunction with reductions in disease activity.1Objectives:To evaluate individual changes in depressive symptoms over 52 weeks in RA patients initiating treatment with TCZ.Methods:We analyzed data from a large German multicenter observational study of patients with active RA who initiated TCZ therapy during routine clinical care (ML29087 ARATA study;NCT02251860). The Beck Depression Inventory-II (BDI-II), a self-report questionnaire for depression screening that has been validated in RA, was used to assess symptoms of depression. Patients were classified by baseline BDI-II scores into depression categories of no (BDI-II<14), mild (BDI-II 14-19), moderate (BDI-II 20-28), and severe depression (BDI-II≥29).2Individual changes in BDI-II scores between baseline and week 52 were assessed. Erythrocyte sedimentation rate was used as the acute phase reactant in Disease Activity Score-28 joints (DAS28) assessments.Results:Of 1155 patients enrolled from 108 clinical centers in Germany between May 2014 and July 2018, 474 completed the BDI-II at baseline (BDI-II cohort); baseline characteristics were similar to those of patients who did not complete the BDI-II. Approximately half of patients in the BDI-II cohort had BDI-II scores indicating no depression (248; 52.3%); the remaining patients had mild (87; 18.4%), moderate (84; 17.7%), or severe (55; 11.6%) depression. The mean (SD) baseline characteristics of the BDI-II cohort were 55.5 (12.5) yrs of age, 75.7% female, 10.6 (9.2) yrs RA duration, 4.9 (1.2) DAS28, and 24.3 (10.2) Clinical Disease Activity Index (CDAI). Baseline DAS28 and CDAI scores were similar among different depression subgroups, but patients with severe depression were more likely to be female (87.3% vs 70.6% for no depression) and had higher levels of anxiety, suicidal ideation, fatigue, pain, and sleep disturbance than patients with no or milder depression.A total of 229 of the 474 patients (48.3%) in the BDI-II cohort completed the BDI-II at both baseline and week 52. At 52 weeks, the depression category of approximately half of patients with depressive symptoms at baseline changed to a lower level or no depression (Figure 1). Moderate to large improvements in BDI-II from baseline (>10 points) were reported by 33.3% to 38.5% of patients with baseline depressive symptoms (Figure 2).Conclusion:At 52 weeks after initiating TCZ, the depressive disease burden was reduced. Future analyses with a representative patient cohort will be aimed at exploring whether improvements in depression occur independent of reductions in disease activity.References:[1]Behrens F et al.Arthritis Rheumatol2019;71(suppl 10):abstr1414.[2]Smarr KL, Keefer AL.Arthritis Care Res2011;63(S11):S454-66.Acknowledgments:This study was sponsored by Chugai Pharma Germany GmbH and Roche Pharma AG. Sharon L. Cross and Kirsten Dahm provided medical writing services supported by Chugai. Statistical analyses were provided by Roche Pharma AG.Disclosure of Interests:Frank Behrens Grant/research support from: Pfizer, Janssen, Chugai, Celgene, Lilly and Roche, Consultant of: Pfizer, AbbVie, Sanofi, Lilly, Novartis, Genzyme, Boehringer, Janssen, MSD, Celgene, Roche and Chugai, Gerd Rüdiger Burmester Consultant of: AbbVie Inc, Eli Lilly, Gilead, Janssen, Merck, Roche, Pfizer, and UCB Pharma, Speakers bureau: AbbVie Inc, Eli Lilly, Gilead, Janssen, Merck, Roche, Pfizer, and UCB Pharma, Martin Feuchtenberger Consultant of: Abbvie, BMS, Chugai, Sanofi, Speakers bureau: Abbvie, BMS, Celgene, Chugai, Jansen-Cilag, Lilly, Pfizer, Roche, Sanofi, UCB, Herbert Kellner: None declared, Cornelia Kühne Grant/research support from: Novartis, Amgen, Roche/Chugai, Pfizer, Celgene, AbbVie, Sanofi, Anke Liebhaber: None declared, Maren Sieburg: None declared, Siegfried Wassenberg: None declared, Christina Luig Employee of: Roche Pharma AG, Michael W. Hofmann Employee of: Chugai Pharma Germany GmbH, Christopher Amberger Grant/research support from: Chugai Pharma Germany GmbH, Consultant of: Chugai Pharma Germany GmbH
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43

Walker, Roslyn Adele. "Remembering Roy Sieber (1923–2001)." African Arts 50, no. 3 (September 2017): 22–29. http://dx.doi.org/10.1162/afar_a_00354.

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44

Kamra, Chander. "Geriatric anesthesia Frederick Sieber (Ed.)." Canadian Journal of Anesthesia/Journal canadien d'anesthésie 55, no. 2 (February 2008): 132–33. http://dx.doi.org/10.1007/bf03016330.

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45

Prince, Thomas. "Smoothing Calabi–Yau toric hypersurfaces using the Gross–Siebert algorithm." Compositio Mathematica 157, no. 7 (June 17, 2021): 1441–91. http://dx.doi.org/10.1112/s0010437x21007132.

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We explain how to form a novel dataset of Calabi–Yau threefolds via the Gross–Siebert algorithm. We expect these to degenerate to Calabi–Yau toric hypersurfaces with certain Gorenstein (not necessarily isolated) singularities. In particular, we explain how to ‘smooth the boundary’ of a class of four-dimensional reflexive polytopes to obtain polarised tropical manifolds. We compute topological invariants of a compactified torus fibration over each such tropical manifold, expected to be homeomorphic to the general fibre of the Gross–Siebert smoothing. We consider a family of examples related to products of reflexive polygons. Among these we find $14$ topological types with $b_2=1$ that do not appear in existing lists of known rank-one Calabi–Yau threefolds.
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46

Pogrebnyak, Aleksandr A. "Exception and Rule. Political and economic arguments of N.I. Sieber against Marginalism before its triumph." Terra Economicus 18, no. 3 (September 25, 2020): 108–24. http://dx.doi.org/10.18522/2073-6606-2020-18-3-108-124.

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The article proposes an analysis of the critical arguments expressed by N.I. Sieber regarding the concept of value, which is accepted by economists of the subjective school. Sieber made these critical arguments in his dissertation, published in 1871. However, they remain valid for Marginalism, the principles of which basically continue the line of the subjective school (Leon Walras was among the authors cited by Sieber). In the analysis of Sieberʼs position, not only logic was taken into account, but also the rhetoric of his argumentation, which makes it possible to identify a broader context within which this position remains relevant. Sieber criticizes the views of economists of the subjective school from the standpoint of the classical school. The latter, as the basis for the constitution of value, considers the average, typical state of economic life, while the former is based on the consideration of an isolated, exceptional moment – that is, the moment when a radical change in the parameters of economic activity takes place. To describe this «exceptional moment», Sieber uses a number of metaphorical images, such as state of siege, threats to life and health, the situation of immigrants, etc. Sieberʼs use of these images allows us to compare his arguments with a number of the most important positions of political theorists of the 20th century (K. Schmitt, W. Benjamin, M. Foucault, G. Agamben) associated with such concepts as «sovereignty», «state of exception», «bare life». As a result, Sieberʼs perspective can be viewed as an anticipation of the modern criticism of neoliberalism – an ideology in which the marginalist understanding of the economy is used as an essential resource for the formation of a biopolitical paradigm for managing peopleʼs lives.
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Marco, J. Alberto, Juan F. Sanz-Cervera, F. Sancenon, J. Jakupovic, A. Rustaiyant, and F. Mohamadit. "Oplopanone derivatives monoterpene glycosides from Artemisia sieberi." Phytochemistry 34, no. 4 (November 1993): 1061–65. http://dx.doi.org/10.1016/s0031-9422(00)90714-3.

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48

Bässler, K. H. "Nachruf auf Prof. Dr. med. G. Siebert." Zeitschrift für Ernährungswissenschaft 30, no. 1 (February 1991): 72. http://dx.doi.org/10.1007/bf01910735.

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49

Behmanesh, B., G. A. Heshmati, M. Mazandaran, M. B. Rezaei, A. R. Ahmadi, E. O. Ghaemi, and S. Bakhshandeh Nosrat. "Chemical Composition and Antibacterial Activity from Essential Oil of Artemisia sieberi Besser subsp. Sieberi in North of Iran." Asian Journal of Plant Sciences 6, no. 3 (March 15, 2007): 562–64. http://dx.doi.org/10.3923/ajps.2007.562.564.

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50

Alhaithloul, Haifa Abdulaziz S. "Impact of Combined Heat and Drought Stress on the Potential Growth Responses of the Desert Grass Artemisia sieberi alba: Relation to Biochemical and Molecular Adaptation." Plants 8, no. 10 (October 15, 2019): 416. http://dx.doi.org/10.3390/plants8100416.

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Artemisia sieberi alba is one of the important plants frequently encountered by the combined effect of drought and heat stress. In the present study, we investigated the individual and combined effect of drought and heat stress on growth, photosynthesis, oxidative damage, and gene expression in A. sieberi alba. Drought and heat stress triggered oxidative damage by increasing the accumulation of hydrogen peroxide, and therefore electrolyte leakage. The accumulation of secondary metabolites, such as phenol and flavonoids, and proline, mannitol, inositol, and sorbitol, was increased due to drought and heat stress exposure. Photosynthetic attributes including chlorophyll synthesis, stomatal conductance, transpiration rate, photosynthetic efficiency, and chlorophyll fluorescence parameters were drastically reduced due to drought and heat stress exposure. Relative water content declined significantly in stressed plants, which was evident by the reduced leaf water potential and the water use efficiency, therefore, affecting the overall growth performance. Relative expression of aquaporin (AQP), dehydrin (DHN1), late embryogenesis abundant (LEA), osmotin (OSM-34), and heat shock proteins (HSP70) were significantly higher in stressed plants. Drought triggered the expression of AQP, DHN1, LEA, and OSM-34 more than heat, which improved the HSP70 transcript levels. A. sieberi alba responded to drought and heat stress by initiating key physio-biochemical and molecular responses, which were distinct in plants exposed to a combination of drought and heat stress.
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