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Journal articles on the topic 'Siemens Aktiengesellschaft. Medical Solutions'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Landreau, André. "Siemens Medical Solutions Diagnostics: témoignage d’utilisateur pour Biotribune." Bio Tribune Magazine 22, S1 (2007): 30–32. http://dx.doi.org/10.1007/s11834-007-0011-8.

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Heuer, Claudia. "Siemens im Kaufrausch." kma - Klinik Management aktuell 12, no. 02 (2007): 28–30. http://dx.doi.org/10.1055/s-0036-1574088.

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Drei Akquisitionen in den vergangenen drei Quartalen, Investitionssummen von über sechs Milliarden Euro. Siemens Medical Solutions hat das Tempo angezogen und die Konkurrenz in Zugzwang gebracht. Jüngstes Mitglied der Siemens-Familie ist seit Januar dieses Jahres die Gesellschaft für Systemforschung und Dienstleistungen im Gesundheitswesen (GSD). Ein Kauf, der an den Machtverhältnissen rüttelt.

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Heuer, Claudia. "Stapellauf." kma - Klinik Management aktuell 12, no. 07 (2007): 10. http://dx.doi.org/10.1055/s-0036-1574274.

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Die Westfälische Wilhelms-Universität (WWU) kann im Rahmen ihrer Exzellenzinitiative auf ein neues Vorzeigeinstitut verweisen. Mithilfe einer Public Private Partnership zwischen der WWU und Siemens Medical Solutions wurde das Europäische Institut für Molekulare Bildgebung (EIMI) aus der Taufe gehoben.

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Miller, Andrew A., and Aaron K. Phillips. "A Contemporary Case Study Illustrating the Integration of Health Information Technologies into the Organisation and Clinical Practice of Radiation Oncology." Health Information Management 34, no. 4 (2005): 136–45. http://dx.doi.org/10.1177/183335830503400407.

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The development of software in radiation oncology departments has seen the increase in capability from the Record and Verify software focused on patient safety to a fully-fledged Oncology Information System (OIS). This paper reports on the medical aspects of the implementation of a modern Oncology Information System (IMPAC MultiAccess®, also known as the Siemens LANTIS®) in a New Zealand hospital oncology department. The department was successful in translating paper procedures into electronic procedures, and the report focuses on the changes in approach to organisation and data use that occur

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Benndorf, Goetz, Benjamin Claus, Charles M. Strother, Lee Chang, and Richard P. Klucznik. "Increased Cell Opening and Prolapse of Struts of a Neuroform Stent in Curved Vasculature:Value of Angiographic Computed Tomography: Technical Case Report." Operative Neurosurgery 58, suppl_4 (2006): ONS—E380—ONS—E380. http://dx.doi.org/10.1227/01.neu.0000205287.06739.e1.

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Abstract Objective and Importance: To describe the use of a new imaging tool, angiographic computed tomography, for visualization of cell opening and strut prolapse of a Neuroform 2 stent (Boston Scientific/Target, Fremont, CA) placed in curved vasculature for treatment of a basilar tip aneurysm. Clinical Presentation: A 46-year-old woman presented with an unruptured 8-mm basilar tip aneurysm with a wide patulous neck. Intervention: A 4 × 20-mm Neuroform 2 stent was placed across the aneurysm neck. Angiographic computed tomographic scanning was performed using a flat detector biplane angiograp

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Darwal, Maureen A., Zakaria Hakma, Mandy J. Binning, et al. "Endovascular Coil Embolization of a Posterior Communicating Artery Aneurysm: 2-Dimensional Operative Video." Operative Neurosurgery 19, no. 6 (2020): E597—E598. http://dx.doi.org/10.1093/ons/opaa278.

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Abstract Since the International Subarachnoid Aneurysm Trial,1 endovascular treatment has been the favored treatment for appropriate ruptured intracranial aneurysms. While our endovascular technology has advanced to allow us to treat the majority of intracranial aneurysms, simple coil embolization is still the most common modality. This video demonstrates the fundamentals of aneurysm catheterization and coiling for safe treatment. In addition, the set-up and devices are detailed. This video is to add to the library of basic techniques that will aid a large number of practitioners. This patient

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Shah, Pooja, Amish Sharma, Jayanti Gyawali, Sharma Paudel, Shanta Lall Shrestha, and Surendra Maharjan. "Dose optimization in computed tomography of brain using CARE kV and CARE Dose 4D." Radiography Open 4, no. 1 (2018): 9. http://dx.doi.org/10.7577/radopen.3110.

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Background: Computed Tomography (CT) scan of brain is the most widely used CT examination. Latest CT scanners have the potential to deliver very low radiation dose by utilizing tube potential and tube current modulation techniques. We aim to determine the application of CARE kV (tube potential modulation) and CARE Dose4D (tube current modulation) in CT scan of brain. Both CARE kV and CARE Dose4D are well-established innovative technology of Siemens Medical Solutions. Methodology: A prospective hospital-based study was conducted during four months at Tribhuvan University Teaching Hospital

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Allouch, Gamal. "Morphological study of the skull sutures and their relationships to skull morphology in young camels (Camelus dromedarius)." Open Veterinary Journal 12, no. 5 (2022): 718. http://dx.doi.org/10.5455/ovj.2022.v12.i5.17.

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Objective: The sutures are associated with anatomical and physiological differences in skull camels. There is a deficiency in the information regarding the anatomy of dromedary camels, especially on fibrous joints (sutures) of the camels skull. Aim: The goal of this work was to give a detailed gross anatomical and radiographic description of the sutures in the camels skull. This description may be of great importance for the veterinarians to differentiate between the suture and the fracture of the head in the radiographic photos. Methods: The current study was conducted on 10 skulls of the How

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Algeciras-Schimnich, Alicia, David E. Bruns, James C. Boyd, Sandra C. Bryant, Kristin A. La Fortune, and Stefan KG Grebe. "Failure of Current Laboratory Protocols to Detect Lot-to-Lot Reagent Differences: Findings and Possible Solutions." Clinical Chemistry 59, no. 8 (2013): 1187–94. http://dx.doi.org/10.1373/clinchem.2013.205070.

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BACKGROUND Maintaining consistency of results over time is a challenge in laboratory medicine. Lot-to-lot reagent changes are a major threat to consistency of results. METHODS For the period October 2007 through July 2012, we reviewed lot validation data for each new lot of insulin-like growth factor 1 (IGF-1) reagents (Siemens Healthcare Diagnostics) at Mayo Clinic, Rochester, MN, and the University of Virginia, Charlottesville, VA. Analyses of discarded patient samples were used for comparison of lots. For the same period, we determined the distributions of reported patient results for each

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Kim, Hyeon-Sik, Byeong-il Lee, and Jae-Sung Ahn. "Assessment of MicroPET Image Quality Based on Reconstruction Methods and Post-Filtering." Applied Sciences 11, no. 18 (2021): 8707. http://dx.doi.org/10.3390/app11188707.

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The accuracy of positron emission tomography (PET) imaging is hampered by the partial volume effect (PVE), which causes image blurring and sampling. The PVE produces spillover phenomena, making PET analysis difficult. Generally, the PVE values vary based on reconstruction methods and filtering. Thus, selection of the proper reconstruction and filtering method can ensure accurate and high-quality PET images. This study compared the values of factors (recovery coefficient (RC), uniformity, and spillover ratio (SOR)) associated with different reconstruction and post-filtering methods using a mous

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Mohamed, Reda. "Anatomical and Radiographic Study on the Skull and Mandible of the African Lion (Panthera leo)." Journal of Morphological Sciences 36, no. 03 (2019): 174–81. http://dx.doi.org/10.1055/s-0039-1691756.

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Objective The taxonomic affiliations can be detected via the skull morphology. The objective of this study was to give a detailed gross anatomical and radiographic description of the bones and foramina of the skull and mandible of the lion. This information could be used in the identification of the skull and mandible of the lion, which is of great importance in taxonomic affiliation and to help the zoo veterinarians to detect, diagnose, and treat head conditions. Materials and Methods The current work was conducted on two skulls and mandibles of lions. The skulls and mandible were prepared us

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Vasiliev, A. Yu, E. B. Petrova, M. V. Fedorova, S. B. Efimova, and P. N. Kordatov. "The results of standard echocardiography and use of Velocity Vector Imaging technology after surgical revascularization in patients with coronary artery disease." Bulletin of Siberian Medicine 18, no. 2 (2019): 31–43. http://dx.doi.org/10.20538/1682-0363-2019-2-31-43.

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The aim of the study was to assess the impact of surgical revascularization on left ventricular function using standard echocardiographic study and Velocity Vector Imaging technology. Materials and methods. 40 patients with ischemic heart disease were examined before and 12 days, 6, 12 and 24 months after coronary artery bypass grafting (CABG). A standard echocardiographic (EchoCG) study was performed on ultrasound scanner Acuson Х 300 (Siemens, USA) with a 5–1 MHz sector multifrequency sensor. For objective assessment of myocardial function, the analysis of left ventricular (LV) deformation a

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Harris, Emma, Ruchi Sinnatamby, Elizabeth O’Flynn, Anna M. Kirby, and Jeffrey C. Bamber. "A Cross-Machine Comparison of Shear-Wave Speed Measurements Using 2D Shear-Wave Elastography in the Normal Female Breast." Applied Sciences 11, no. 20 (2021): 9391. http://dx.doi.org/10.3390/app11209391.

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Quantitative measures of radiation-induced breast stiffness are required to support clinical studies of novel breast radiotherapy regimens and exploration of personalised therapy, however, variation between shear-wave elastography (SWE) machines may limit the usefulness of shear-wave speed (cs) for this purpose. Mean cs measured in four healthy volunteers’ breasts and a phantom using 2D-SWE machines Acuson S2000 (Siemens Medical Solutions) and Aixplorer (Supersonic Imagine) were compared. Shear-wave speed was measured in the skin region, subcutaneous adipose tissue and parenchyma. cs estimates

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Terada, Yukinori, Taketo Hatano, Yasunori Nagai, Makoto Hayase, Masashi Oda, and Takehiko Nakamura. "Intraprocedural Detection of Cerebral Hyperperfusion by Flat Detector Computed Tomography in the Evaluation of Cerebral Blood Volume during Carotid Artery Stenting." Interventional Neuroradiology 20, no. 4 (2014): 502–9. http://dx.doi.org/10.15274/inr-2014-10044.

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Cerebral blood volume (CBV) can be measured using a C-arm flat detector angiographic system. The present report describes a case in which cerebral hyperperfusion was detected with the Neuro parenchymal blood volume (PBV) system (syngo Neuro PBV IR, Siemens Medical Solutions, Erlangen, Germany) during carotid artery stenting (CAS). An 89-year-old man was referred to our hospital for cerebral brain infarction and severe stenosis of the left carotid artery. CAS was performed, and Neuro PBV was used to measure CBV both during and after the procedure. Postoperative Neuro PBV revealed dramatically i

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Forsberg, F., R. J. Ro, J. B. Liu, K. J. Lipcan, M. Potoczek, and L. N. Nazarian. "Monitoring Angiogenesis in Human Melanoma Xenograft Model Using Contrast-Enhanced Ultrasound Imaging." Ultrasonic Imaging 30, no. 4 (2008): 237–46. http://dx.doi.org/10.1177/016173460803000407.

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The potential for noninvasive monitoring and quantification of tumor angiogenesis with contrast-enhanced ultrasound imaging has been investigated in a murine cancer model. Seventy athymic nude mice were implanted with the human melanoma cell line DB-1 but only 30 of these were available for the final study. The 30 mice were divided into three groups (10 mice/group), which were studied with contrast-enhanced ultrasound imaging 4, 5 or 6 weeks post-implantation. Power Doppler and pulse inversion harmonic imaging (PIHI) were performed (in real time and intermittently) with a Sonoline Elegra scann

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Ketelsen, Dominik, Markus Buchgeister, Andreas Korn, et al. "High-Pitch Computed Tomography Coronary Angiography—A New Dose-Saving Algorithm: Estimation of Radiation Exposure." Radiology Research and Practice 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/724129.

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Purpose. To estimate effective dose and organ equivalent doses of prospective ECG-triggered high-pitch CTCA.Materials and Methods. For dose measurements, an Alderson-Rando phantom equipped with thermoluminescent dosimeters was used. The effective dose was calculated according to ICRP 103. Exposure was performed on a second-generation dual-source scanner (SOMATOM Definition Flash, Siemens Medical Solutions, Germany). The following scan parameters were used: 320 mAs per rotation, 100 and 120 kV, pitch 3.4 for prospectively ECG-triggered high-pitch CTCA, scan range of 13.5 cm, collimation mm with

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Saenger, Amy K., Christina Lockwood, Christine L. Snozek, et al. "Catecholamine Interference in Enzymatic Creatinine Assays." Clinical Chemistry 55, no. 9 (2009): 1732–36. http://dx.doi.org/10.1373/clinchem.2009.127373.

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Abstract Background: Enzymatic creatinine assays are routinely used in clinical laboratories to provide more accurate estimated glomerular filtration rates and to avoid a perceived lack of analytical specificity associated with picrate (Jaffe) methods. Negative interferences with the enzymatic creatinine assay, which we noted in several patients on dopamine or dobutamine, prompted our further investigation into interference of catecholamines with enzymatic methods. Methods: Spiked solutions of dopamine, dobutamine, epinephrine, and norepinephrine were added to pooled sera at catecholamine conc

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Mlinaric, Ana, Marija Milos, Désirée Coen Herak, et al. "Autovalidation and automation of the postanalytical phase of routine hematology and coagulation analyses in a university hospital laboratory." Clinical Chemistry and Laboratory Medicine (CCLM) 56, no. 3 (2018): 454–62. http://dx.doi.org/10.1515/cclm-2017-0402.

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AbstractBackground:The need to satisfy high-throughput demands for laboratory tests continues to be a challenge. Therefore, we aimed to automate postanalytical phase in hematology and coagulation laboratory by autovalidation of complete blood count (CBC) and routine coagulation test results (prothrombin time [PT], international normalized ratio [PT-INR], activated partial thromboplastin time [APTT], fibrinogen, antithrombin activity [AT] and thrombin time [TT]). Work efficacy and turnaround time (TAT) before and after implementation of automated solutions will be compared.Methods:Ordering pane

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Kumar, J., Bing Bai, Francesca Zanderigo, et al. "In Vivo Brain Imaging, Biodistribution, and Radiation Dosimetry Estimation of [11C]Celecoxib, a COX-2 PET Ligand, in Nonhuman Primates." Molecules 23, no. 8 (2018): 1929. http://dx.doi.org/10.3390/molecules23081929.

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COX-2 selective inhibitors (COXIBs) are non-steroidal anti-inflammatory drugs (NSAIDs), with fewer side effects compared with non-selective NSAIDs, and are used for the treatment of arthritis, headaches, and other inflammatory diseases of the brain and peripheral tissues. Radiolabeled COXIBs may permit positron emission tomography (PET) imaging of COX-2 localization and activity in diseases, enable monitoring of inflammatory processes, and determine target occupancy of COX-2 activity by NSAIDs, thus, accelerating the development of novel CIXIBs. We synthesized [11C]celecoxib, one of the COXIBs

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Sudhir, Rashmi, M. V. T. Krishna Mohan, Bogala Shilpa, and Veeraiah K. Chaudhary. "Efficacy of acoustic radiation force impulse elastography in differentiation of benign and malignant lymph nodes." Asian Journal of Oncology 03, no. 02 (2017): 106–10. http://dx.doi.org/10.4103/asjo.asjo_48_17.

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Abstract Aims and Objectives: Aim of this study was to assess the clinical usefulness of Acoustic Radiation Force Impulse (ARFI) elastography imaging in differentiating benign and malignant/metastatic superficial nodes. Methods and Materials: ARFI elastography (Siemens Medical Solutions, Mountain View, CA) using Virtual touch Tissue Imaging (VTI) technique was performed and Shear wave velocity (m/sec) was measured in 85 patients (mean age, 49 years; range, 16–72 years) with 126 lymph nodes (96 axillary, 21 cervical and 9 inguinal nodes) which were biopsied and histo-pathologically correlated.

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Brugts, M. P., J. G. L. M. Luermans, E. G. W. M. Lentjes, et al. "Heterophilic antibodies may be a cause of falsely low total IGF1 levels." European Journal of Endocrinology 161, no. 4 (2009): 561–65. http://dx.doi.org/10.1530/eje-09-0316.

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BackgroundA low serum total IGF1 is considered as a diagnostic indicator of GH deficiency (GHD) in the presence of hypopituitarism. Introduction of IRMA and chemiluminescent immunometric assay (CLIA) IGF1 immunoassays has introduced endogenous antibodies as a new source of interference. In general, this goes unnoticed and might lead to unnecessary diagnostic and therapeutic interventions.CaseA 56-year-old man was referred with a decline in physical performance, unexplained osteopenia, and weight loss of 3 kg over the past 8 months. Although clinical signs and symptoms were unremarkable, labora

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McLeish, Susan A., Kay Burt, and Kostas Papasouliotis. "Analytical quality assessment and method comparison of immunoassays for the measurement of serum cobalamin and folate in dogs and cats." Journal of Veterinary Diagnostic Investigation 31, no. 2 (2019): 164–74. http://dx.doi.org/10.1177/1040638718824073.

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Serum cobalamin and folate are often measured in cats and dogs as part of laboratory testing for intestinal disease, small intestinal dysbiosis, or exocrine pancreatic deficiency. We performed an analytical validation of human immunoassays for cobalamin and folate measurement (AIA-900 analyzer, Tosoh Bioscience) and compared results with those obtained using chemiluminescence assays (Immulite 2000 analyzer, Siemens Medical Solutions Diagnostics). Accuracy, precision, total observable error (TEobs%), and σ values were calculated for the immunoassays. Correlation and agreement were evaluated wit

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Postnov, A. A., T. A. Konakova, D. V. Kalaeva, A. I. Batalov, N. B. Vikhrova, and I. N. Pronin. "DIFFERENTIAL DIAGNOSIS OF BRAIN GLIOMAS: THE POSSIBILITIES OF DYNAMIC PET-CT WITH 18F-FLUORODEOXYGLUCOSE." Russian Electronic Journal of Radiology 11, no. 1 (2021): 78–87. http://dx.doi.org/10.21569/2222-7415-2021-11-1-78-87.

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Purpose. The aim of this prospective study, which included the analysis of data from 52 patients with primary brain gliomas, was to look for additional PET-CT biomarkers determined on the basis of the analysis of the first minute of dynamic PET scanning in order to increase the specificity and sensitivity of differential diagnosis of gliomas. 18F-FDG was administered simultaneously with the data collection began. Materials and methods. The study group included data of 52 patients, 27 men, 25 women, age 18-80 years, median 48 years + 12. Histologically, these were glioblastomas (n= 19), anaplas

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Nottmeier, Eric W., and Phillip M. Young. "Image-Guided Placement of Occipitocervical Instrumentation Using a Reference Arc Attached to the Headholder." Operative Neurosurgery 66, suppl_1 (2010): ons—138—ons—142. http://dx.doi.org/10.1227/01.neu.0000346264.66833.b3.

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Abstract Objective: To develop a safe and accurate method of image-guided placement of instrumentation in the upper cervical spine and occiput in which the reference arc is fixed to the headholder. Methods: The authors describe a technique for placing screws at the occipital, C1, and C2 levels using 3-dimensional image guidance in which the reference arc is fixed to the headholder. Technical details are discussed as well as modifications to the technique to maximize navigation accuracy and decrease the need for re-registration. One of 2 paired systems, the BrainLAB Vector Vision system (BrainL

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Nalbant, Mustafa Orhan, Aysegul Akdogan Gemici, Mehmet Karadag, and Ercan Inci. "The efficiency of volumetric apparent diffusion coefficient histogram analysis in breast papillary neoplasms." Journal of Surgery and Medicine 7, no. 5 (2023): 00. http://dx.doi.org/10.28982/josam.7715.

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Background/Aim: Papillary neoplasia encompasses both malignant and benign lesions, and core needle biopsy (CNB) is crucial in their diagnosis. Histological findings determine their management. Here we compare volumetric apparent diffusion coefficient (ADC) histogram analysis of carcinomas and benign pathologies identified by histopathology from excisional biopsies. Methods: This retrospective study included 524 patients who underwent breast magnetic resonance imaging (MRI) for a suspicious breast mass from January 2018 to October 2022. Patients with benign lesions, incompatible ultrasound-guid

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Schifman, Ron B., Tan T. Nguyen, and Susan T. Page. "Reliability of Point-of-Care Capillary Blood Glucose Measurements in the Critical Value Range." Archives of Pathology & Laboratory Medicine 138, no. 7 (2014): 962–66. http://dx.doi.org/10.5858/arpa.2013-0455-oa.

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Context.—Point-of-care glucose (POCG) testing on capillary blood specimens is central to maintaining glycemic control in patients with diabetes. Although there are known performance issues with POCG methods, especially for maintaining tight glucose control, there is little information about the accuracy of results in the critical ranges that may involve life-threatening conditions. Objectives.—To evaluate the reliability of POCG measurements in critical, high (&gt;600 mg/dL) and low (&lt;40 mg/dL) ranges. Design.—One-year retrospective analysis of POCG (ACCU-CHEK glucose meter, Roche D

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Barra, Cristina B., Maria Jussara F. Fontes, Marco Túlio G. Cintra, et al. "Oral corticosteroids for asthma exacerbations might be associated with adrenal suppression: Are physicians aware of that?" Revista da Associação Médica Brasileira 63, no. 10 (2017): 899–903. http://dx.doi.org/10.1590/1806-9282.63.10.899.

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Summary Introduction: Oral corticosteroids (OCS) are a mainstay of treatment for asthma exacerbations, and short-term OCS courses were generally considered to be safe. Nevertheless, frequent short-term OCS courses could lead to hypothalamic-pituitary-adrenal (HPA) axis dysfunction. Our study aimed at investigating the integrity of the HPA axis in children with persistent asthma or recurrent wheezing at the beginning of an inhaled corticosteroids (ICS) trial. Method: Morning basal cortisol was assessed just before the beginning of ICS, and 30, 60, and 90 days later, using Immulite® Siemens Medi

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Fiedler, E., M. Pavel, A. Pfahlberg, et al. "Attenuation correction of SPECT images based on separately performed CT." Nuklearmedizin 44, no. 01 (2005): 20–28. http://dx.doi.org/10.1055/s-0038-1623924.

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Summary Aim: A new software approach uses separately acquired CT images for attenuation correction after retrospective fusion with the SPECT data. This study evaluates the effect of this CT-based attenuation correction on indium- 111-pentetreotide-SPECT images. Methods: Indium- 111-pentetreotide-SPECT imaging using a dual-head gamma camera e.cam (Siemens Medical Solutions, Erlangen, Germany) as well as separate spiral computed tomography (CT) was performed in 13 patients. After fusion of SPECT and CT data, the bilinear attenuation coefficients were calculated for each pixel in the CT image vol

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Albergueiro, Rita, Vera Antunes, and João Santos. "Effect of OSEM Reconstruction Iteration Number and Monte Carlo Collimator Modeling on 166Ho Activity Quantification in SPECT/CT." Applied Sciences 15, no. 3 (2025): 1589. https://doi.org/10.3390/app15031589.

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Background: Accurate reconstruction and quantification in the post-therapy SPECT/CT imaging of 166Ho microspheres for hepatic malignancies is crucial for treatment evaluation. This present study aimed to explore the impact of the OSEM reconstruction parameters on SPECT/CT image features for dose distribution determination, using Hybrid Recon™ (Hermes Medical Solutions AB) and full Monte Carlo (MC) collimator modeling. Methods: Image quality and activity quantification were assessed through two acquisitions of the Jaszczak phantom using a Siemens Symbia Intevo Bold SPECT/CT system. The datasets

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Zatsarynin, Serhii. "Market Segmentation of Innovative Products Using Genetic Algoritms." Marketing and Digital Technologies 5, no. 2 (2021): 67–74. http://dx.doi.org/10.15276/mdt.5.2.2021.6.

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One way to increase the company's competitiveness is to find new market niches. The market niche is the result of innovations that stimulate hidden, potential demand, as a result of which the company, developing a new market, avoids intense competition and receives a higher rate of return. It is proved that the growing number and complexity of tasks in the field of marketing research, working with a large amount of information, leads to the need to group data. The aim of the study is to develop a universal approach to solving the problem of market segmentation of innovative products based on a

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Briasoulis, E. C., D. Papamichael, D. Tzachanis, et al. "Predictive value of EGFR mRNA levels assessed by quantitative RT-PCR in primary tumors of patients treated with cetuximab for metastatic colorectal cancer." Journal of Clinical Oncology 25, no. 18_suppl (2007): 4121. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.4121.

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4121 Background: The epidermal growth factor receptor (EGFR) protein is the nominal target of the monoclonal therapeutic antibody cetuximab. Yet, repeated failure of EGFR immunohistochemistry (IHC) in predicting treatment outcome has questioned its value in colorectal cancer (CRC). Therefore search for a valid molecular predictor of cetuximab efficacy is highly justified. Methods: 64 CRC patients were treated with standard chemotherapy plus cetuximab in the metastatic setting. RNA was isolated from fixed tumor tissue samples employing an experimental method based on magnetic beads from Siemens

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Nimsky, Christopher, Oliver Ganslandt, Bernd Hofmann, and Rudolf Fahlbusch. "Limited Benefit of Intraoperative Low-field Magnetic Resonance Imaging in Craniopharyngioma Surgery." Neurosurgery 53, no. 1 (2003): 72–81. http://dx.doi.org/10.1227/01.neu.0000068728.08237.af.

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Abstract OBJECTIVE To investigate the benefit of intraoperative low-field magnetic resonance imaging (MRI) in craniopharyngioma surgery. METHODS We used a 0.2-T Magnetom Open scanner (Siemens Medical Solutions, Erlangen, Germany) that was located in a radiofrequency-shielded operating theater for intraoperative MRI. The head of the patient was placed in the fringe field of the scanner, so that standard microinstruments could be used. In transsphenoidal surgery, T1-weighted coronal and sagittal images were acquired. In transcranial surgery, a three-dimensional, gradient echo, T1-weighted, fast

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Güssow, Arne, Sabine Thalmeier, Ruth Gostelow, et al. "Method Validation and Establishment of Reference Intervals for an Insulin-like Growth Factor-1 Chemiluminescent Immunoassay in Cats." Veterinary Sciences 10, no. 9 (2023): 575. http://dx.doi.org/10.3390/vetsci10090575.

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Previously, radioimmunoassay (RIA) has been the only assay to measure insulin-like growth factor-1 (IGF-1) to diagnose hypersomatotropism (HS). Due to radiation concerns, availability, and the cost of IGF-1 RIA, validation of assays for automated analysers such as a chemiluminescent immunoassay (CLIA) is needed. The aim of this study was to validate a CLIA for measurement of feline IGF-1 (IMMULITE 2000® XPi, Siemens Medical Solutions Diagnostics, Malvern, PA, USA) compared to IGF1 RIA, establish reference interval (RI), and determine a cut-off value for diagnosis of HS in diabetic cats. Valida

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STEIN, J., and P. DOUGLAS. "Beyond stress echo: assessing vascular health with cardiovascular ultrasoundproceedings of symposium presented on June 13, 2003, at the 14th Annual Scientific Sessions of the American Society of Echocardiography (supported by an educational grant from SIEMENS Medical Solutions)." Journal of the American Society of Echocardiography 17, no. 6 (2004): 681. http://dx.doi.org/10.1016/s0894-7317(04)00263-9.

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Bhasin, Ashu, Padma Srivastava, and Senthil S. Kumaran. "Correlation of DTI-Derived Measures to Therapy-Mediated Recovery after Stroke." Neurology India 69, no. 5 (2021): 1210–16. http://dx.doi.org/10.4103/0028-3886.329584.

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Introduction: Corticospinal tracts (CST) forms the basis of motor neurophysiology after stroke. Motor skill recovery has been correlated well to the microstructural properties of CST in both hemispheres. Functional imaging has opened up new possibilities of imaging functionality of cortex and fiber tracts in the brain. We studied therapy-induced changes in blood oxygenation level-dependent (BOLD) and DTI imaging on 20 chronic stroke patients at baseline, 8, and 24 weeks. Settings and Design: All the patients were subjected to MR imaging on a 1.5 T MR scanner. We used block design for BOLD with

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Lu, Xiu-Yun, Xi Guo, Qi Zhang, et al. "Early Assessment of Chemoradiotherapy Response for Locally Advanced Pancreatic Ductal Adenocarcinoma by Dynamic Contrast-Enhanced Ultrasound." Diagnostics 12, no. 11 (2022): 2662. http://dx.doi.org/10.3390/diagnostics12112662.

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Objective: To evaluate the value of dynamic contrast-enhanced ultrasound (DCE-US) and quantitative parameters in early prediction of tumor response to chemoradiotherapy (CRT) in patients with locally advanced pancreatic ductal adenocarcinoma (LAPC). Patients and Methods: In this prospective study, patients with biopsy-proved and histopathologically proved LAPC who underwent regular CRT were recruited. DCE-US evaluations were performed before and four months after CRT. SonoVue-enhanced contrast-enhanced ultrasound (CEUS) was performed by an ultrasound system (ACUSON Sequoia; Siemens Medical Sol

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Karademir, F., A. E. Yildiz, T. Firat, and O. Ulger. "AB1819-HPR INTRA-RATER RELIABILITY OF SHEAR WAVE ELASTOGRAPHY FOR THE QUANTIFICATION OF THUMB MUSCLE ELASTICITY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 2141.2–2141. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2931.

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BackgroundShear wave elastography (SWE) is a technique that evaluates tissue elasticity by applying an acoustic radiation force impulse [1]. It is undetermined how reliable this modality is in assessing thumb muscles. Quantitative evaluation of muscle stiffness in conditions such as trapeziometacarpal osteoarthritis where increased fibrosis, muscle tone, spasm, and contractures can be seen can provide important information about the pathophysiology and prognosis of the diseases [2].ObjectivesThis study aimed to assess the intra-rater reliability of thumb muscle elasticity and thickness in heal

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de Oliveira, Wagner, José Olimpio Rodrigues Batista, Tiago Novais, et al. "OpenCare5G: O-RAN in Private Network for Digital Health Applications." Sensors 23, no. 2 (2023): 1047. http://dx.doi.org/10.3390/s23021047.

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Digital Health is a new way for medicine to work together with computer engineering and ICT to carry out tests and obtain reliable information about the health status of citizens in the most remote places in Brazil in near-real time, applying new technologies and digital tools in the process. InovaHC is the technological innovation core of the Clinics Hospital of the Faculty of Medicine of the University of São Paulo (HCFMUSP). It is the first national medical institution to seek new opportunities offered by 5G technology and test its application in the first private network for Digital Health

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Wowra, Berndt, Alexander Muacevic, Jörg-Christian Tonn, Stefan O. Schoenberg, Maximilian Reiser, and Karin A. Herrmann. "OBLITERATION DYNAMICS IN CEREBRAL ARTERIOVENOUS MALFORMATIONS AFTER CYBERKNIFE RADIOSURGERY." Neurosurgery 64, suppl_2 (2009): A102—A109. http://dx.doi.org/10.1227/01.neu.0000339201.31176.c9.

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Abstract OBJECTIVE To investigate the time-dependent obliteration of cerebral arteriovenous malformations (cAVM) after CyberKnife radiosurgery (CKRS) (Accuray, Inc., Sunnyvale, CA) by means of sequential 3-T, 3-dimensional (3D), time-of-flight (TOF) magnetic resonance angiography (MRA), and volumetry of the arteriovenous malformation (AVM) nidus. METHODS In this prospective study, 3D TOF MRA was performed on 20 patients with cAVMs treated by single-fraction CKRS. Three-dimensional TOF MRA was performed on a 3-T, 32-channel magnetic resonance scanner (Magnetom TIM Trio; Siemens Medical Solution

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Bertsch, Thomas, Wilhelm Behringer, Sabine Blaschke, et al. "Diagnostic Accuracy of the Tina-Quant D-Dimer Gen.2 Assay with Age-Adjusted Cut-Off Ranges for Evaluation of Patients with Suspected Deep Vein Thrombosis or Pulmonary Embolism." Blood 136, Supplement 1 (2020): 14–15. http://dx.doi.org/10.1182/blood-2020-139235.

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Introduction: Fibrin degradation products, D-Dimer and X-oligomers, are biomarkers for activation of coagulation. D-Dimer testing is recommended as an additional diagnostic tool for proximal deep vein thrombosis (DVT) and pulmonary embolism (PE), in conjunction with clinical presentation and pre-test probability (Lim, et al. Blood Adv. 2018). D-Dimer levels naturally increase in patients over the age of 50 years, which reduces the specificity of D-Dimer levels as a diagnostic aid for proximal DVT and PE in older patients. We conducted a study to assess the diagnostic accuracy of the Tina-quant

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Carpenter, John-Paul, Francisco Alpendurada, Monica Deac, et al. "Impact of Myocardial Iron Loading On Right Ventricular Function." Blood 114, no. 22 (2009): 2012. http://dx.doi.org/10.1182/blood.v114.22.2012.2012.

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Abstract Abstract 2012 Poster Board I-1034 Background: Cardiovascular magnetic resonance (CMR) is being increasingly used worldwide for monitoring chelation therapy in transfusion-dependent β-thalassemia patients. The assessment of cardiac iron loading using myocardial T2 star (T2*) is a reliable, quick and non-invasive method which can be combined with highly accurate and reproducible cardiac volume and function measurements. It has previously been noted that myocardial siderosis (T2*<20ms) is associated with progressive impairment in left ventricular (LV) function but little is known abou

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Kanne, Celeste K., and Vivien A. Sheehan. "Surgical Splenectomy Alters Red Cell Rheology in Patients with Sickle Cell Disease." Blood 132, Supplement 1 (2018): 1092. http://dx.doi.org/10.1182/blood-2018-99-117202.

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Abstract Background: Many patients with sickle cell disease (SCD) require a surgical splenectomy for repeat splenic sequestration or hypersplenism, resulting in worsening anemia and/or thrombocytopenia, or abdominal discomfort. Higher rates of thrombosis, pain crises and acute chest syndrome (ACS) have been reported following surgical splenectomy, although the reasons for this are not known. We hypothesize that this clinical worsening post-splenectomy is due to hemorheological changes; studies of the effects of surgical splenectomy on hemorheology in non-SCD animal models found significant red

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Eliasberg, Claire, Tony Chen, James Kelly, et al. "Poster 203: Mechanical Loading Effects on OA Progression Following ACL Injury and Reconstruction in a Murine Model: Radiographic Assessment of Synovial Fibroblast Activity." Orthopaedic Journal of Sports Medicine 10, no. 7_suppl5 (2022): 2325967121S0076. http://dx.doi.org/10.1177/2325967121s00764.

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Objectives: Anterior cruciate ligament (ACL) injury is one of the leading orthopedic injuries in young individuals and even with surgical repair it is reported that around 50% of patients develop post-traumatic osteoarthritis (PTOA). Although ACL reconstruction improves anterior-posterior knee joint stability and cartilage contact biomechanics, some studies have shown persistent abnormalities in the tibiofemoral kinematics. Extensive rehabilitation work is often required following both ACL tear and ACL reconstruction surgery. New bone formation (osteophyte) and synovial inflammation (synovitis

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Itzep, Nelda, Siddharth Jadhav, Celeste K. Kanne, and Vivien A. Sheehan. "Spontaneous Healing of Avascular Necrosis of the Femoral Head in Sickle Cell Disease." Blood 132, Supplement 1 (2018): 4924. http://dx.doi.org/10.1182/blood-2018-99-119328.

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Abstract Background. Avascular necrosis (AVN) is a serious complication of sickle cell disease (SCD) that can lead to significant morbidity including chronic pain and physical impairment with treatment depending on the patient's pain severity and functional limitation. Patient age, hemoglobin levels, and abnormal rheology, particularly high blood viscosity, or thickness, and percentage of dense red blood cells, defined as cells >1.11 mg/mL have been identified as risk factors for the development of AVN, but their contributions to the subsequent clinical course has not been described. The na

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Ramm, Peter, Armin Klumpp, Alan Mathewson, Kafil M. Razeeb, and Reinhard Pufall. "The European 3D Heterogeneous Integration Platform (e-BRAINS) - a Particular Focus on Reliability and Low-Temperature Processes for 3D Integrated Sensor Systems." Additional Conferences (Device Packaging, HiTEC, HiTEN, and CICMT) 2015, DPC (2015): 001847–84. http://dx.doi.org/10.4071/2015dpc-tha11.

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The European 3D heterogeneous integration platform has been established by the consortium of the Integrated Project e-BRAINS [1], where technologies of the following relevant main categories of 3D integration are provided to enable future applications of smart sensor systems:3D System-on-Chip Integration - 3D-SOC: TSV technology for stacking of thinned devices or large IC blocks (global level),3D Wafer-Level-Packaging - 3D-WLP: embedding technology with through-polymer vias (TPV) for stacking of thinned ICs on wafer-level (no TSV), and3D System-in-Package - 3D-SIP: 3D stacking of packaged devi

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Pfob, André, Chris Sidey-Gibbons, Richard G. Barr, et al. "Abstract PD11-05: Intelligent shear-wave elastography to reduce unnecessary biopsies in breast cancer diagnosis (INSPiRED 002): An international, multicenter analysis." Cancer Research 82, no. 4_Supplement (2022): PD11–05—PD11–05. http://dx.doi.org/10.1158/1538-7445.sabcs21-pd11-05.

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Abstract Background: Breast ultrasound identifies additional carcinomas not detected in mammography, but has a higher rate of false-positive findings which result in more unnecessary breast biopsies. Shear-Wave Elastography (SWE), an ultrasound technique used to quantify the stiffness of a lesion, showed promising results to improve the diagnostic performance of B-mode breast ultrasound but also to miss some cancers. As the stiffness of a lesion is found to be influenced by individual patient characteristics, incorporation of lesion stiffness in more individualized assessments may be key to th

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"Acknowledgement to Siemens Medical Solutions." Journal of Cardiovascular Computed Tomography 3, no. 1 (2009): A2. http://dx.doi.org/10.1016/s1934-5925(09)00068-9.

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"Acknowledgement to Siemens Medical Solutions." Journal of Cardiovascular Computed Tomography 3 (November 2009): A2. http://dx.doi.org/10.1016/s1934-5925(09)00623-6.

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Sawhney, Mohanbir, Shankar Balakrishnan, Maryam Balali, Brit Gould, Steven Stark, and Larry Xu. "Siemens Medical Solutions: Creating a Customer-Focused Organization for Solutions Marketing." Kellogg School of Management Cases, January 20, 2017, 1–26. http://dx.doi.org/10.1108/case.kellogg.2016.000305.

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Siemens Medical Solutions (SMS) offered innovative products and systems, clinical solutions, and services for medical professionals. Its latest project, transforming a hospital to digital records and processes, was experiencing serious delays that had damaged the relationship with the client. Management believed the underlying problem was that SMS was not using the correct approach to organization and processes for solutions marketing. The executives in charge of on-time completion and successful delivery of the project must now agree on a different recommendation.Students will examine the inf

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B., Stroetmann, and Aisenbrey A. "Medical Knowledge Management in Healthcare Industry." April 27, 2012. https://doi.org/10.5281/zenodo.1058321.

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The Siemens Healthcare Sector is one of the world's largest suppliers to the healthcare industry and a trendsetter in medical imaging and therapy, laboratory diagnostics, medical information technology, and hearing aids. Siemens offers its customers products and solutions for the entire range of patient care from a single source – from prevention and early detection to diagnosis, and on to treatment and aftercare. By optimizing clinical workflows for the most common diseases, Siemens also makes healthcare faster, better, and more cost effective. The optimization of clinical workflows requires

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