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Journal articles on the topic 'Signal-To-Signal Translation'

Author: Grafiati

Published: 20 July 2024

Last updated: 31 July 2025

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1

Harfiya, Latifa Nabila, Ching-Chun Chang, and Yung-Hui Li. "Continuous Blood Pressure Estimation Using Exclusively Photopletysmography by LSTM-Based Signal-to-Signal Translation." Sensors 21, no. 9 (2021): 2952. http://dx.doi.org/10.3390/s21092952.

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Monitoring continuous BP signal is an important issue, because blood pressure (BP) varies over days, minutes, or even seconds for short-term cases. Most of photoplethysmography (PPG)-based BP estimation methods are susceptible to noise and only provides systolic blood pressure (SBP) and diastolic blood pressure (DBP) prediction. Here, instead of estimating a discrete value, we focus on different perspectives to estimate the whole waveform of BP. We propose a novel deep learning model to learn how to perform signal-to-signal translation from PPG to arterial blood pressure (ABP). Furthermore, us

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Proud, Christopher G. "Signalling to translation: how signal transduction pathways control the protein synthetic machinery." Biochemical Journal 403, no. 2 (2007): 217–34. http://dx.doi.org/10.1042/bj20070024.

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Recent advances in our understanding of both the regulation of components of the translational machinery and the upstream signalling pathways that modulate them have provided important new insights into the mechanisms by which hormones, growth factors, nutrients and cellular energy status control protein synthesis in mammalian cells. The importance of proper control of mRNA translation is strikingly illustrated by the fact that defects in this process or its control are implicated in a number of disease states, such as cancer, tissue hypertrophy and neurodegeneration. Signalling pathways such

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Zhao, Baining, Zhewen Niu, Qiheng Liang, et al. "Signal-to-Signal Translation for Fault Diagnosis of Bearings and Gears With Few Fault Samples." IEEE Transactions on Instrumentation and Measurement 70 (2021): 1–10. http://dx.doi.org/10.1109/tim.2021.3123433.

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Jeong, Singi, Jaemin Shin, and Yusung Kim. "A Signal-to-Data Translation Model for Robust Backscatter Communications." IEEE Access 10 (2022): 27440–52. http://dx.doi.org/10.1109/access.2022.3155879.

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Wang, Qing, and Hsin-Sheng Yang. "The Impact of Pdcd4, a Translation Inhibitor, on Drug Resistance." Pharmaceuticals 17, no. 10 (2024): 1396. http://dx.doi.org/10.3390/ph17101396.

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Programmed cell death 4 (Pdcd4) is a tumor suppressor, which has been demonstrated to efficiently suppress tumorigenesis. Biochemically, Pdcd4 binds with translation initiation factor 4A and represses protein translation. Beyond its role in tumor suppression, growing evidence suggests that Pdcd4 enhances the chemosensitivity of several anticancer drugs. To date, numerous translational targets of Pdcd4 have been identified. These targets govern important signal transduction pathways, and their attenuation may improve chemosensitivity or overcome drug resistance. This review will discuss the sig

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Zaragoza-Gómez, Andre, Emilio García-Caffarel, Yuridia Cruz-Zamora та ін. "The Nβ motif of NaTrxh directs secretion as an endoplasmic reticulum transit peptide and variations might result in different cellular targeting". PLOS ONE 18, № 10 (2023): e0287087. http://dx.doi.org/10.1371/journal.pone.0287087.

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Soluble secretory proteins with a signal peptide reach the extracellular space through the endoplasmic reticulum-Golgi conventional pathway. During translation, the signal peptide is recognised by the signal recognition particle and results in a co-translational translocation to the endoplasmic reticulum to continue the secretory pathway. However, soluble secretory proteins lacking a signal peptide are also abundant, and several unconventional (endoplasmic reticulum/Golgi independent) pathways have been proposed and some demonstrated. This work describes new features of the secretion signal ca

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Piazzi, Manuela, Alberto Bavelloni, Angela Gallo, Irene Faenza, and William L. Blalock. "Signal Transduction in Ribosome Biogenesis: A Recipe to Avoid Disaster." International Journal of Molecular Sciences 20, no. 11 (2019): 2718. http://dx.doi.org/10.3390/ijms20112718.

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Energetically speaking, ribosome biogenesis is by far the most costly process of the cell and, therefore, must be highly regulated in order to avoid unnecessary energy expenditure. Not only must ribosomal RNA (rRNA) synthesis, ribosomal protein (RP) transcription, translation, and nuclear import, as well as ribosome assembly, be tightly controlled, these events must be coordinated with other cellular events, such as cell division and differentiation. In addition, ribosome biogenesis must respond rapidly to environmental cues mediated by internal and cell surface receptors, or stress (oxidative

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Chen, Zhuo. "Signal Recognition for English Speech Translation Based on Improved Wavelet Denoising Method." Advances in Mathematical Physics 2021 (September 18, 2021): 1–9. http://dx.doi.org/10.1155/2021/6811192.

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The signal corresponding to English speech contains a lot of redundant information and environmental interference information, which will produce a lot of distortion in the process of English speech translation signal recognition. Based on this, a large number of studies focus on encoding and processing English speech, so as to achieve high-precision speech recognition. The traditional wavelet denoising algorithm plays an obvious role in the recognition of English speech translation signals, which mainly depends on the excellent local time-frequency domain characteristics of the wavelet signal

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Mazo, Chantell, and Jamie C. Theobald. "To keep on track during flight, fruitflies discount the skyward view." Biology Letters 10, no. 2 (2014): 20131103. http://dx.doi.org/10.1098/rsbl.2013.1103.

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When small flying insects go off their intended course, they use the resulting pattern of motion on their eye, or optic flow, to guide corrective steering. A change in heading generates a unique, rotational motion pattern and a change in position generates a translational motion pattern, and each produces corrective responses in the wingbeats. Any image in the flow field can signal rotation, but owing to parallax, only the images of nearby objects can signal translation. Insects that fly near the ground might therefore respond more strongly to translational optic flow that occurs beneath them,

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Pyhtila, B., T. Zheng, P. J. Lager, J. D. Keene, M. C. Reedy, and C. V. Nicchitta. "Signal sequence- and translation-independent mRNA localization to the endoplasmic reticulum." RNA 14, no. 3 (2008): 445–53. http://dx.doi.org/10.1261/rna.721108.

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Robinson, A., O. M. R. Westwood, and B. M. Austen. "Interactions of signal peptides with signal-recognition particle." Biochemical Journal 266, no. 1 (1990): 149–56. http://dx.doi.org/10.1042/bj2660149.

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The mechanisms whereby isolated or synthetic signal peptides inhibit processing of newly synthesized prolactin in microsome-supplemented lysates from reticulocytes and wheat-germ were investigated. At a concentration of 5 microM, a consensus signal peptide reverses the elongation arrest imposed by the signal-recognition particle (SRP), and at higher concentrations in addition inhibits elongation of both secretory and non-secretory proteins. A photoreactive form of a synthetic signal peptide cross-links under u.v. illumination to the 54 kDa and 68 kDa subunits of SRP, whereas the major cross-li

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Karagyozov, Luchezar, Petar N. Grozdanov, and Frank-D. Böhmer. "The translation attenuating arginine-rich sequence in the extended signal peptide of the protein-tyrosine phosphatase PTPRJ/DEP1 is conserved in mammals." PLOS ONE 15, no. 12 (2020): e0240498. http://dx.doi.org/10.1371/journal.pone.0240498.

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The signal peptides, present at the N-terminus of many proteins, guide the proteins into cell membranes. In some proteins, the signal peptide is with an extended N-terminal region. Previously, it was demonstrated that the N-terminally extended signal peptide of the human PTPRJ contains a cluster of arginine residues, which attenuates translation. The analysis of the mammalian orthologous sequences revealed that this sequence is highly conserved. The PTPRJ transcripts in placentals, marsupials, and monotremes encode a stretch of 10–14 arginine residues, positioned 11–12 codons downstream of the

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Tan, Ying. "Design of Intelligent Speech Translation System Based on Deep Learning." Mobile Information Systems 2022 (September 6, 2022): 1–7. http://dx.doi.org/10.1155/2022/2463812.

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In order to solve the problem of low translation accuracy caused by complex sentence parameters in traditional machine translation systems, a method based on deep learning was proposed. First, MCU SPCE061A is used to study the problem of complex digital signal. The training data in the synchronous translation server support the translation services of a large number of users, and the translation results were displayed through the session interface of the user terminal. The PMDL model is used to detect the keyword signal, record the PCM audio data, and slice the collected pulse code modulation

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Sahinbegovic, Hana, Alexander Vdovin, Renata Snaurova, et al. "Length-Dependent Translation Efficiency of ER-Destined Proteins." Current Issues in Molecular Biology 45, no. 8 (2023): 6717–27. http://dx.doi.org/10.3390/cimb45080425.

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Gene expression is a fundamental process that enables cells to produce specific proteins in a timely and spatially dependent manner. In eukaryotic cells, the complex organization of the cell body requires precise control of protein synthesis and localization. Certain mRNAs encode proteins with an N-terminal signal sequences that direct the translation apparatus toward a specific organelle. Here, we focus on the mechanisms governing the translation of mRNAs, which encode proteins with an endoplasmic reticulum (ER) signal in human cells. The binding of a signal-recognition particle (SRP) to the

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Im, Chang-Hwan, and Jinuk Kwon. "S2S-STARGAN: NOVEL SIGNAL-TO-SIGNAL TRANSLATION METHOD BASED ON STARGAN TO GENERATE ARTIFICIAL EEG FOR SSVEP-BASED BRAIN-COMPUTER INTERFACES." IBRO Neuroscience Reports 15 (October 2023): S949. http://dx.doi.org/10.1016/j.ibneur.2023.08.2004.

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Sarker, Shameema, Kenneth E. Rudd, and Donald Oliver. "Revised Translation Start Site for secM Defines an Atypical Signal Peptide That Regulates Escherichia coli secA Expression." Journal of Bacteriology 182, no. 19 (2000): 5592–95. http://dx.doi.org/10.1128/jb.182.19.5592-5595.2000.

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ABSTRACT The secretion-responsive regulation of Escherichia coli secA occurs by coupling its translation to the translation and secretion of an upstream regulator, secM (formerly geneX). We revise the translational start site for secM, defining a new signal peptide sequence with an extended amino-terminal region. Mutational studies indicate that certain atypical amino acyl residues within this extended region are critical for propersecA regulation.

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Yang, Yang, and Meng Su. "Research on the Application of Computer-Assisted Translation Technology in Translation Teaching." Mobile Information Systems 2022 (September 16, 2022): 1–11. http://dx.doi.org/10.1155/2022/1898066.

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In order to improve the quality of translation teaching, this study combines computer-aided translation technology to construct a translation teaching system, uses digital signal processing as a technical means to process waveform data online, and designs digital models for signal flow. Moreover, this study designs a digital filter to suppress waveform noise to improve the accuracy of amplitude measurement and uses a hardware algorithm for accumulating shift and averaging to correct the baseline stacking effect in real time. In addition, this study builds an intelligent translation software sy

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Martin, Maria Wirtz, Anna Wacker, and Harald Schwalbe. "Quantifizierung von Transkription und Translation von Riboschaltern." BIOspektrum 30, no. 3 (2024): 292–95. http://dx.doi.org/10.1007/s12268-024-2198-6.

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AbstractRiboswitches change their secondary structure upon ligand binding, sending a signal that triggers transcriptional or translational gene regulation. Our dual-readout assay allows the simultaneous detection of ligand-dependent changes in transcription and translation. The cell-free assay utilizes the parallel detection of the fluorescent Mango (IV) aptamer downstream of the transcribed mRNA and GFP fluorescence to quantify transcription and translation products in the presence or absence of ligand.

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Fukumoto, Yasunori, Masayoshi Ikeuchi, Yuji Nakayama, and Yasumitsu Ogra. "Rad17 Translocates to Nucleolus upon UV Irradiation through Nucleolar Localization Signal in the Central Basic Domain." International Journal of Molecular Sciences 23, no. 20 (2022): 12300. http://dx.doi.org/10.3390/ijms232012300.

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The nucleolus is a non-membranous structure in the nucleus and forms around ribosomal DNA repeats. It plays a major role in ribosomal biogenesis through the transcription of ribosomal DNA and regulates mRNA translation in response to cellular stress including DNA damage. Rad17 is one of the proteins that initiate and maintain the activation of the ATR pathway, one of the major DNA damage checkpoints. We have recently reported that the central basic domain of Rad17 contains a nuclear localization signal and that the nuclear translocation of Rad17 promotes its proteasomal degradation. Here, we s

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Choi, Jinah, Zhenming Xu, and Jing-hsiung Ou. "Triple Decoding of Hepatitis C Virus RNA by Programmed Translational Frameshifting." Molecular and Cellular Biology 23, no. 5 (2003): 1489–97. http://dx.doi.org/10.1128/mcb.23.5.1489-1497.2003.

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ABSTRACT Ribosomes can be programmed to shift from one reading frame to another during translation. Hepatitis C virus (HCV) uses such a mechanism to produce F protein from the −2/+1 reading frame. We now report that the HCV frameshift signal can mediate the synthesis of the core protein of the zero frame, the F protein of the −2/+1 frame, and a 1.5-kDa protein of the −1/+2 frame. This triple decoding function does not require sequences flanking the frameshift signal and is apparently independent of membranes and the synthesis of the HCV polyprotein. Two consensus −1 frameshift sequences in the

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Finidori, J., L. Rizzolo, A. Gonzalez, G. Kreibich, M. Adesnik, and D. D. Sabatini. "The influenza hemagglutinin insertion signal is not cleaved and does not halt translocation when presented to the endoplasmic reticulum membrane as part of a translocating polypeptide." Journal of Cell Biology 104, no. 6 (1987): 1705–14. http://dx.doi.org/10.1083/jcb.104.6.1705.

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The co-translational insertion of polypeptides into endoplasmic reticulum membranes may be initiated by cleavable amino-terminal insertion signals, as well as by permanent insertion signals located at the amino-terminus or in the interior of a polypeptide. To determine whether the location of an insertion signal within a polypeptide affects its function, possibly by affecting its capacity to achieve a loop disposition during its insertion into the membrane, we have investigated the functional properties of relocated insertion signals within chimeric polypeptides. An artificial gene encoding a

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Nicchitta, Christopher V., Rachel S. Lerner, Samuel B. Stephens, Rebecca D. Dodd, and Brook Pyhtila. "Pathways for compartmentalizing protein synthesis in eukaryotic cells: the template-partitioning model." Biochemistry and Cell Biology 83, no. 6 (2005): 687–95. http://dx.doi.org/10.1139/o05-147.

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mRNAs encoding signal sequences are translated on endoplasmic reticulum (ER) - bound ribosomes, whereas mRNAs encoding cytosolic proteins are translated on cytosolic ribosomes. The partitioning of mRNAs to the ER occurs by positive selection; cytosolic ribosomes engaged in the translation of signal-sequence-bearing proteins are engaged by the signal-recognition particle (SRP) pathway and subsequently trafficked to the ER. Studies have demonstrated that, in addition to the SRP pathway, mRNAs encoding cytosolic proteins can also be partitioned to the ER, suggesting that RNA partitioning in the e

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Iida, Y., and D. Kanagu. "1R0900 Quantification analysis of translation initiation signal of mRNA : Effect of nucleotides from +4 to +6 on strength of signal." Seibutsu Butsuri 42, supplement2 (2002): S93. http://dx.doi.org/10.2142/biophys.42.s93_3.

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Rong, Chao, Dingfan Zhang, Yuwen Cao, and Zhengbin Li. "Analyze the Difference Between Rotational and Translational Motions Produced by High-speed Train." Journal of Physics: Conference Series 2651, no. 1 (2023): 012141. http://dx.doi.org/10.1088/1742-6596/2651/1/012141.

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Abstract The development of fiber optic gyroscope technology makes it possible to directly measure the rotational ground-motion. The joint observation of the three-component rotational seismometer and the traditional three-component translational seismometer is a trend of future. In this paper, the translational and rotational signals generated during the high-speed trainway are studied, and the three-component translational and rotational seismometers are fixed together to realize the joint recording of the high-speed trainway signal. Comparing the translational and rotational three-component

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Bergsten, S. E., and E. R. Gavis. "Role for mRNA localization in translational activation but not spatial restriction of nanos RNA." Development 126, no. 4 (1999): 659–69. http://dx.doi.org/10.1242/dev.126.4.659.

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Patterning of the anterior-posterior body axis during Drosophila development depends on the restriction of Nanos protein to the posterior of the early embryo. Synthesis of Nanos occurs only when maternally provided nanos RNA is localized to the posterior pole by a large, cis-acting signal in the nanos 3′ untranslated region (3′UTR); translation of unlocalized nanos RNA is repressed by a 90 nucleotide Translational Control Element (TCE), also in the 3′UTR. We now show quantitatively that the majority of nanos RNA in the embryo is not localized to the posterior pole but is distributed throughout

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Jiang, Xue Mei, Xiao Li Tu, Bo Li, and Xiao Mei Zhang. "Reversible Watermarking Algorithm in DFT Domain for 2D CAD Engineering Graphics." Advanced Materials Research 765-767 (September 2013): 826–30. http://dx.doi.org/10.4028/www.scientific.net/amr.765-767.826.

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In this paper, extract the coordinates of the vertices of the 2D CAD graphics to construct the complex-valued signal. And use the signal to do the DFT. The encrypted watermark is embedded into the DFT amplitude by using the IDE algorithm. Experimental results show that the algorithm has good invisibility, with good reversibility. The algorithm has robust against the attacks such as combination of translation, rotation, translation and adding an entity.

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Sanchez, Robersy, Xiaodong Yang, Thomas Maher, and Sally A. Mackenzie. "Discrimination of DNA Methylation Signal from Background Variation for Clinical Diagnostics." International Journal of Molecular Sciences 20, no. 21 (2019): 5343. http://dx.doi.org/10.3390/ijms20215343.

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Advances in the study of human DNA methylation variation offer a new avenue for the translation of epigenetic research results to clinical applications. Although current approaches to methylome analysis have been helpful in revealing an epigenetic influence in major human diseases, this type of analysis has proven inadequate for the translation of these advances to clinical diagnostics. As in any clinical test, the use of a methylation signal for diagnostic purposes requires the estimation of an optimal cutoff value for the signal, which is necessary to discriminate a signal induced by a disea

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Kanaji, Sachiko, Jun Iwahashi, Yuichiro Kida, Masao Sakaguchi, and Katsuyoshi Mihara. "Characterization of the Signal That Directs Tom20 to the Mitochondrial Outer Membrane." Journal of Cell Biology 151, no. 2 (2000): 277–88. http://dx.doi.org/10.1083/jcb.151.2.277.

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Tom20 is a major receptor of the mitochondrial preprotein translocation system and is bound to the outer membrane through the NH2-terminal transmembrane domain (TMD) in an Nin-Ccyt orientation. We analyzed the mitochondria-targeting signal of rat Tom20 (rTom20) in COS-7 cells, using green fluorescent protein (GFP) as the reporter by systematically introducing deletions or mutations into the TMD or the flanking regions. Moderate TMD hydrophobicity and a net positive charge within five residues of the COOH-terminal flanking region were both critical for mitochondria targeting. Constructs without

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ZHANG, LEI, XIAOLIN WU, and PAUL BAO. "NOISY SIGNAL COMPRESSION BY WAVELET TRANSFORM WITH OPTIMAL DOWNSAMPLING." International Journal of Wavelets, Multiresolution and Information Processing 01, no. 04 (2003): 407–23. http://dx.doi.org/10.1142/s0219691303000268.

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This paper presents a wavelet transform (WT) based on simultaneous de-noising and compression scheme for noisy signal. Due to the downsampling in decomposition process, the orthogonal wavelet transform (OWT) is translation variant, which significantly hinders its performance in coding and denoising. In this paper the wavelet bintree decomposition (WBD), which is equivalent to a translation invariant WT, is first formed and an optimal downsampling route is then traversed among all the routes of the bintree. The WT with the optimal route would most effectively decorrelate and compactly represent

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Brijesh, K. Soni* Deepak Mishra. "BRAIN-COMPUTER-INTERFACE: A CONCEPTUAL WORKING APPROACHES FOR NEUROTECHNOLOGY." Global Journal of Engineering Science and Research Management 3, no. 7 (2016): 113–17. https://doi.org/10.5281/zenodo.58280.

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This article addresses to the core part of a neurotechnology known as Brain-Computer-Interface and abbreviated as BCI. It is most growing research area in this era for neurotechnologists. Whole portion of this article broadly describe three working stages of BCI-System such as signal acquisition, signal processing and signal application, and signal processing further categorized as signal preprocessing, feature extraction, feature classification and feature translation. However working functionality varies according to its interfacing technique used as invasive-interface, semi-invasive-interfa

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Wild, Klemens, Matthias M. M. Becker, Georg Kempf, and Irmgard Sinning. "Structure, dynamics and interactions of large SRP variants." Biological Chemistry 401, no. 1 (2019): 63–80. http://dx.doi.org/10.1515/hsz-2019-0282.

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Abstract Co-translational protein targeting to membranes relies on the signal recognition particle (SRP) system consisting of a cytosolic ribonucleoprotein complex and its membrane-associated receptor. SRP recognizes N-terminal cleavable signals or signal anchor sequences, retards translation, and delivers ribosome-nascent chain complexes (RNCs) to vacant translocation channels in the target membrane. While our mechanistic understanding is well advanced for the small bacterial systems it lags behind for the large bacterial, archaeal and eukaryotic SRP variants including an Alu and an S domain.

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Shome, Debaditya, Pritam Sarkar, and Ali Etemad. "Region-Disentangled Diffusion Model for High-Fidelity PPG-to-ECG Translation." Proceedings of the AAAI Conference on Artificial Intelligence 38, no. 13 (2024): 15009–19. http://dx.doi.org/10.1609/aaai.v38i13.29422.

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The high prevalence of cardiovascular diseases (CVDs) calls for accessible and cost-effective continuous cardiac monitoring tools. Despite Electrocardiography (ECG) being the gold standard, continuous monitoring remains a challenge, leading to the exploration of Photoplethysmography (PPG), a promising but more basic alternative available in consumer wearables. This notion has recently spurred interest in translating PPG to ECG signals. In this work, we introduce Region-Disentangled Diffusion Model (RDDM), a novel diffusion model designed to capture the complex temporal dynamics of ECG. Traditi

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TODA, HIROSHI, and ZHONG ZHANG. "PERFECT TRANSLATION INVARIANCE WITH A WIDE RANGE OF SHAPES OF HILBERT TRANSFORM PAIRS OF WAVELET BASES." International Journal of Wavelets, Multiresolution and Information Processing 08, no. 04 (2010): 501–20. http://dx.doi.org/10.1142/s0219691310003602.

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It is well known that a Hilbert transform pair of wavelet bases improves the lack of translation invariance of the discrete wavelet transform. However, its shapes and improvement are limited by the difficulty in applying the Hilbert transform pair to a discrete signal. In this paper, novel Hilbert transform pairs of wavelet bases, which are based on a Meyer wavelet and have a wide range of shapes, are proposed to create perfect translation invariance, and their calculation method is designed to apply these wavelet bases to any discrete signal. Therefore, perfect translation invariance is achie

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Bartkutė, Darija, and Daiva Verikaitė-Gaigalienė. "Spatial deictics in translation." Languages in Contrast 20, no. 1 (2019): 84–106. http://dx.doi.org/10.1075/lic.18007.bar.

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Abstract Recent research on deictic elements has made extensive use of translation corpora to demonstrate that asymmetries between translational paradigms signal subtle contrasts from a systemic and pragmatic perspective. The purpose of the present study is to identify translation correspondences of the English spatial demonstrative this in Lithuanian and to discuss the contrastive features within the analytical framework of translational explicitation and implicitation. The results indicate that in the prototypical situational usage there is a high degree of correspondence between this and it

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Lipp, J., N. Flint, M. T. Haeuptle, and B. Dobberstein. "Structural requirements for membrane assembly of proteins spanning the membrane several times." Journal of Cell Biology 109, no. 5 (1989): 2013–22. http://dx.doi.org/10.1083/jcb.109.5.2013.

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We have investigated the structural requirements for the biogenesis of proteins spanning the membrane several times. Proteins containing various combinations of topological signals (signal anchor and stop transfer sequences) were synthesized in a cell-free translation system and their membrane topology was determined. Proteins spanning the membrane twice were obtained when a signal anchor sequence was followed by either a stop transfer sequence or a second signal anchor sequence. Thus, a signal anchor sequence in the second position can function as a stop transfer sequence, spanning the membra

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Kruss, Sebastian. "Signal Amplification and Near-Infrared Translation of Enzymatic Reactions by Nanosensors." ECS Meeting Abstracts MA2025-01, no. 59 (2025): 2800. https://doi.org/10.1149/ma2025-01592800mtgabs.

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Enzymatic reactions are used to detect analytes in a range of biochemical methods. To measure the presence of an analyte, the enzyme is conjugated to a recognition unit and converts a substrate into a (colored) product that is detectable by visible (VIS) light. Thus, the lowest enzymatic turnover that can be detected sets a limit on sensitivity. Here, we report that substrates and products of horseradish peroxidase (HRP) and β-galactosidase change the near-infrared (NIR) fluorescence of (bio)polymer modified single-walled carbon nanotubes (SWCNTs). They translate a VIS signal into a beneficial

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Naveed, Khuram, Bisma Shaukat, and Naveed ur Rehman. "Dual tree complex wavelet transform-based signal denoising method exploiting neighbourhood dependencies and goodness-of-fit test." Royal Society Open Science 5, no. 9 (2018): 180436. http://dx.doi.org/10.1098/rsos.180436.

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A novel signal denoising method is proposed whereby goodness-of-fit (GOF) test in combination with a majority classifications-based neighbourhood filtering is employed on complex wavelet coefficients obtained by applying dual tree complex wavelet transform (DT-CWT) on a noisy signal. The DT-CWT has proven to be a better tool for signal denoising as compared to the conventional discrete wavelet transform (DWT) owing to its approximate translation invariance. The proposed framework exploits statistical neighbourhood dependencies by performing the GOF test locally on the DT-CWT coefficients for t

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Jiang, Rui, Camille-Sophie Bres, Nikola Alic, Evgeny Myslivets, and Stojan Radic. "Translation of Gbps Phase-Modulated Optical Signal From Near-Infrared to Visible Band." Journal of Lightwave Technology 26, no. 1 (2008): 131–37. http://dx.doi.org/10.1109/jlt.2007.912100.

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Alken, Martina, Claudia Rutz, Robert Köchl, et al. "The signal peptide of the rat corticotropin-releasing factor receptor 1 promotes receptor expression but is not essential for establishing a functional receptor." Biochemical Journal 390, no. 2 (2005): 455–64. http://dx.doi.org/10.1042/bj20050113.

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Approximately 5–10% of the GPCRs (G-protein-coupled receptors) contain N-terminal signal peptides that are cleaved off during receptor insertion into the ER (endoplasmic reticulum) membrane by the signal peptidases of the ER. The reason as to why only a subset of GPCRs requires these additional signal peptides is not known. We have recently shown that the signal peptide of the human ETB-R (endothelin B receptor) does not influence receptor expression but is necessary for the translocation of the receptor's N-tail across the ER membrane and thus for the establishment of a functional receptor [K

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Anderson, Emma C., and Andrew M. L. Lever. "Human Immunodeficiency Virus Type 1 Gag Polyprotein Modulates Its Own Translation." Journal of Virology 80, no. 21 (2006): 10478–86. http://dx.doi.org/10.1128/jvi.02596-05.

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ABSTRACT The full-length viral RNA of human immunodeficiency virus type 1 (HIV-1) functions both as the mRNA for the viral structural proteins Gag and Gag/Pol and as the genomic RNA packaged within viral particles. The packaging signal which Gag recognizes to initiate genome encapsidation is in the 5′ untranslated region (UTR) of the HIV-1 RNA, which is also the location of translation initiation complex formation. Hence, it is likely that there is competition between the translation and packaging processes. We studied the ability of Gag to regulate translation of its own mRNA. Gag had a bimod

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Meng, Jing. "Intelligent English Translation Based on Intelligent Speech Waveform Analysis." Mobile Information Systems 2022 (August 21, 2022): 1–13. http://dx.doi.org/10.1155/2022/9408361.

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In order to improve the effectiveness of an intelligent English translation, this paper combines intelligent speech waveform technology to construct an intelligent English translation system. When the modulation method of each signal component is known, this paper takes the overlapping point as the fitting point set and performs fitting with each data point. Moreover, this paper takes the obtained modulation method parameters as eigenvectors and finally performs clustering to obtain the parameter estimation of each single-component signal. In addition, in the case of overlapping points between

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Liu, Shuyi, Shengtao Chen, Zuzhi Chen, and Yongjun Gong. "Fault Diagnosis Strategy Based on BOA-ResNet18 Method for Motor Bearing Signals with Simulated Hydrogen Refueling Station Operating Noise." Applied Sciences 14, no. 1 (2023): 157. http://dx.doi.org/10.3390/app14010157.

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The harsh working environment of hydrogen refueling stations often causes equipment failure and is vulnerable to mechanical noise during monitoring. This limits the accuracy of equipment monitoring, ultimately decreasing efficiency. To address this issue, this paper presents a motor bearing vibration signal diagnosis method that employs a Bayesian optimization (BOA) residual neural network (ResNet). The industrial noise signal of the hydrogenation station is simulated and then combined with the motor bearing signal. The resulting one-dimensional bearing signal is processed and transformed into

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Li, Quan, Liping Xu, Hui Wu, Jing Liu, Jinguo Lin, and Xin Guan. "Differential proteome analysis of the extracts from the xylem of Cinnamomum camphora inhibiting Coriolus versicolor." Holzforschung 72, no. 6 (2018): 459–66. http://dx.doi.org/10.1515/hf-2017-0148.

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AbstractThe proteins ofCoriolus versicolortreated with the acetone extracts ofCinnamomum camphoraxylem has been investigated. The specific proteins found in the extract treatedC. versicolor, were characterized by two-dimensional (2D) gel electrophoresis (2D-GE) and identified by matrix assisted laser desorption ionization (MALDI) combined with tandem time-of-flight microscopy, i.e. TOF-MS/TOF-MS. Most of 474 proteins detected from the pure culture were common metabolic proteins. Nineteen protein spots changed significantly and 17 spots were identified successfully. The 19 proteins were assigne

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DINKOVA, Tzvetanka D., Raul AGUILAR, and Estela SÁNCHEZ DE JIMÉNEZ. "Expression of maize eukaryotic initiation factor (eIF) iso4E is regulated at the translational level." Biochemical Journal 351, no. 3 (2000): 825–31. http://dx.doi.org/10.1042/bj3510825.

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Mechanisms for regulation of gene expression at the translational level have been reported at specific developmental stages in eukaryotes. Control of eukaryotic initiation factor (eIF) 4E availability by insulin/growth factors constitutes a main point of translational regulation. The aim of the present research was to understand the regulatory mechanism(s) behind the differential expression of two main 4E factors present in maize embryonic axes during germination. De novo synthesis of eIFiso4E initiates earlier and is faster than that of eIF4E in maize axes. Insulin addition to maize axes stim

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Bolster, Douglas R., Leonard S. Jefferson, and Scot R. Kimball. "Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin-, amino acid- and exercise-induced signalling." Proceedings of the Nutrition Society 63, no. 2 (2004): 351–56. http://dx.doi.org/10.1079/pns2004355.

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Although insulin, amino acids and exercise individually activate multiple signal transduction pathways in skeletal muscle, one pathway, the phosphatidylinositol 3-kinase (PI3K)–mammalian target of rapamycin (mTOR) signalling pathway, is a target of all three. Activation of the PI3K–mTOR signal transduction pathway results in both acute (i.e. occurring in minutes to hours) and long-term (i.e. occurring in hours to days) up-regulation of protein synthesis through modulation of multiple steps involved in mediating the initiation of mRNA translation and ribosome biogenesis respectively. In additio

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Yang, Ying, and Yusen Wei. "RANDOM INTERPOLATION AVERAGE FOR ECG SIGNAL DENOISING USING MULTIPLE WAVELET BASES." Biomedical Engineering: Applications, Basis and Communications 25, no. 04 (2013): 1350042. http://dx.doi.org/10.4015/s1016237213500427.

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The random interpolation average (RIA) is a simple yet good denoising method. It firstly employed several times of random interpolations to a noisy signal, then applied the wavelet transform (WT) denoising to each interpolated signal and averaged all of the denoised signals to finish the denoising process. In this paper, multiple wavelet bases and the level-dependent threshold estimator were used in the RIA scheme so that it can be more suitable for the electrocardiogram (ECG) signal denoising. The synthetic ECG signal, real ECG signal and four types of noise were used to perform comparison ex

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Dobrikov, M. I., E. Y. Dobrikova, and M. Gromeier. "Dynamic Regulation of the Translation Initiation Helicase Complex by Mitogenic Signal Transduction to Eukaryotic Translation Initiation Factor 4G." Molecular and Cellular Biology 33, no. 5 (2012): 937–46. http://dx.doi.org/10.1128/mcb.01441-12.

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Guo, Li Jie. "Nonlinear Analysis of Mixed Signal Test Based on Graphic Program Design." Applied Mechanics and Materials 539 (July 2014): 489–92. http://dx.doi.org/10.4028/www.scientific.net/amm.539.489.

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In this paper, based on the parabolic interpolation function of nonlinear Lagrange, we establish the mathematical model of business translation graphical teaching method. In order to verify the availability and reliability of the model and algorithm, we test the performance of graphic business English translation platform. After testing the mixed signal of platform, the current with fault is lower than circuit without fault. The peak voltage of triangular wave is about-6V and 6V. According to the response curves of English translation circuit, different sequencers realize the parallel translat

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Jethmalani, Yogita, and Erin M. Green. "Using Yeast to Define the Regulatory Role of Protein Lysine Methylation." Current Protein & Peptide Science 21, no. 7 (2020): 690–98. http://dx.doi.org/10.2174/1389203720666191023150727.

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The post-translational modifications (PTM) of proteins are crucial for cells to survive under diverse environmental conditions and to respond to stimuli. PTMs are known to govern a broad array of cellular processes including signal transduction and chromatin regulation. The PTM lysine methylation has been extensively studied within the context of chromatin and the epigenetic regulation of the genome. However, it has also emerged as a critical regulator of non-histone proteins important for signal transduction pathways. While the number of known non-histone protein methylation events is increas

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He, Jinshen, Hongliang Ba, Jing Feng, et al. "Increased signal intensity, not volume variation of infrapatellar fat pad in knee osteoarthritis: A cross-sectional study based on high-resolution magnetic resonance imaging." Journal of Orthopaedic Surgery 30, no. 1 (2022): 102255362210922. http://dx.doi.org/10.1177/10225536221092215.

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Background Infrapatellar fat pad (IPFP) is regarded as an essential knee tissue involved in osteoarthritis (OA) for its potential structural-related or metabolism-related function. This cross-sectional study aims to identify which part is more related to OA. Methods Patients with knee OA ( n = 53) and healthy controls ( n = 54) were prospectively recruited. Based on high-resolution magnetic resonance imaging with a slice thickness of only 0.35 mm, IPFP structural-related parameters (volume and maximal area), metabolism-related parameter (signal), degeneration indicators, and patellar maltracki

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