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Journal articles on the topic 'Signaling system 7'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 July 2024

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1

Yi-Bing Lin. "Signaling System Number 7." IEEE Potentials 15, no. 3 (1996): 5–8. http://dx.doi.org/10.1109/45.535225.

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2

Modarressi, A. R., and R. A. Skoog. "Signaling System No.7: a tutorial." IEEE Communications Magazine 28, no. 7 (1990): 19–20. http://dx.doi.org/10.1109/35.56239.

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3

Schlanger, G. "An Overview of Signaling System No. 7." IEEE Journal on Selected Areas in Communications 4, no. 3 (1986): 360–65. http://dx.doi.org/10.1109/jsac.1986.1146326.

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4

Appenzeller, H. "Signaling System No. 7 ISDN User Part." IEEE Journal on Selected Areas in Communications 4, no. 3 (1986): 366–71. http://dx.doi.org/10.1109/jsac.1986.1146327.

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5

Willmann, G., and P. J. Kuhn. "Performance modeling of Signaling System No.7." IEEE Communications Magazine 28, no. 7 (1990): 44–56. http://dx.doi.org/10.1109/35.56241.

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6

Marr, F. K. "Signaling System No.7 in corporate networks." IEEE Communications Magazine 28, no. 7 (1990): 72–77. http://dx.doi.org/10.1109/35.56244.

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7

Modarressi, A. R., and R. A. Skoog. "An overview of Signaling System No.7." Proceedings of the IEEE 80, no. 4 (1992): 590–606. http://dx.doi.org/10.1109/5.135382.

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8

Cambron, G. K. "Signaling System No.7 local exchange deployment." Proceedings of the IEEE 80, no. 4 (1992): 628–36. http://dx.doi.org/10.1109/5.135385.

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9

Min Young Chung, Jae Uck You, Dan Keun Sung, and Bong Dae Choi. "Performability analysis of common-channel signaling networks, based on signaling system 7." IEEE Transactions on Reliability 48, no. 3 (1999): 224–33. http://dx.doi.org/10.1109/24.799844.

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10

Bolodeoku, J., C. Anyaeche, M. Bass, and TK Kim. "Presence of Elevated Interleukin – 6 (IL-6) in the Blood of COVID-19 Convalescent Patients (40 – 93 Days) Post Onset of Symptoms Could be an Indicator of Ongoing Activation of the Immune System." Journal of Cellular Signaling 4, no. 4 (2023): 163–68. http://dx.doi.org/10.33696/signaling.4.103.

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IL-6 concentrations rise with the onset of COVID-19 infection and is detected in 68% of patients on admission but is expected to reduce after the acute phase. IL-6 concentrations at time points: (2-7 days), (6-11 days), (11-15 days) and (13-20 days) after intensive care unit (ICU) admission showed the highest level of IL-6 concentrations at time point 2-7 days, we decided to characterize IL-6 concentrations in serum samples collected in the sera of COVID-19 convalescent patients (40 – 93 days) post onset of symptoms. The estimated IL- 6 concentrations detected ranged between 2.65 pg/ml and 29.

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11

Wilson, D. R. "Signaling System No.7, IS-41 and cellular telephony networking." Proceedings of the IEEE 80, no. 4 (1992): 644–52. http://dx.doi.org/10.1109/5.135387.

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12

Jabbari, B. "Routing and congestion control in common channel Signaling System No.7." Proceedings of the IEEE 80, no. 4 (1992): 607–17. http://dx.doi.org/10.1109/5.135383.

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13

Gomes, Enéas R. M., Robson A. S. Santos, and Silvia Guatimosim. "Angiotensin-(1-7)-Mediated Signaling in Cardiomyocytes." International Journal of Hypertension 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/493129.

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The Renin-Angiotensin System (RAS) acts at multiple targets and has its synthesis machinery present in different tissues, including the heart. Actually, it is well known that besides Ang II, the RAS has other active peptides. Of particular interest is the heptapeptide Ang-(1-7) that has been shown to exert cardioprotective effects. In this way, great compilations about Ang-(1-7) actions in the heart have been presented in the literature. However, much less information is available concerning the Ang-(1-7) actions directly in cardiomyocytes. In this paper, we show the actual knowledge about Ang

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Corkrum, Michelle, and Alfonso Araque. "Astrocyte-neuron signaling in the mesolimbic dopamine system: the hidden stars of dopamine signaling." Neuropsychopharmacology 46, no. 11 (2021): 1864–72. http://dx.doi.org/10.1038/s41386-021-01090-7.

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15

Donohoe, D., G. Johannessen, and R. Stone. "Realization of a Signaling System No. 7 Network for AT&T." IEEE Journal on Selected Areas in Communications 4, no. 8 (1986): 1257–61. http://dx.doi.org/10.1109/jsac.1986.1146451.

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16

Zimmerman, Matthew C. "Angiotensin II and angiotensin-1-7 redox signaling in the central nervous system." Current Opinion in Pharmacology 11, no. 2 (2011): 138–43. http://dx.doi.org/10.1016/j.coph.2011.01.001.

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17

Yan, Fei, Chunhai Gao, Tao Tang, and Yao Zhou. "A Safety Management and Signaling System Integration Method for Communication-Based Train Control System." Urban Rail Transit 3, no. 2 (2017): 90–99. http://dx.doi.org/10.1007/s40864-017-0051-7.

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18

Bodiga, Vijaya Lakshmi, and Sreedhar Bodiga. "Renin Angiotensin System in Cognitive Function and Dementia." Asian Journal of Neuroscience 2013 (September 12, 2013): 1–18. http://dx.doi.org/10.1155/2013/102602.

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Angiotensin II represents a key molecule in hypertension and cerebrovascular pathology. By promoting inflammation and oxidative stress, enhanced Ang II levels accelerate the onset and progression of cell senescence. Sustained activation of RAS promotes end-stage organ injury associated with aging and results in cognitive impairment and dementia. The discovery of the angiotensin-converting enzyme ACE2-angiotensin (1–7)-Mas receptor axis that exerts vasodilator, antiproliferative, and antifibrotic actions opposed to those of the ACE-Ang II-AT1 receptor axis has led to the hypothesis that a decre

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19

Aravena, Javier, Johanna Abrigo, Francisco Gonzalez та ін. "Angiotensin (1-7) Decreases Myostatin-Induced NF-κB Signaling and Skeletal Muscle Atrophy". International Journal of Molecular Sciences 21, № 3 (2020): 1167. http://dx.doi.org/10.3390/ijms21031167.

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Myostatin is a myokine that regulates muscle function and mass, producing muscle atrophy. Myostatin induces the degradation of myofibrillar proteins, such as myosin heavy chain or troponin. The main pathway that mediates protein degradation during muscle atrophy is the ubiquitin proteasome system, by increasing the expression of atrogin-1 and MuRF-1. In addition, myostatin activates the NF-κB signaling pathway. Renin–angiotensin system (RAS) also regulates muscle mass. Angiotensin (1-7) (Ang-(1-7)) has anti-atrophic properties in skeletal muscle. In this paper, we evaluated the effect of Ang-(

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20

Mitra, N., and S. D. Usiskin. "Relationship of the Signaling System No.7 protocol architecture to the OSI reference model." IEEE Network 5, no. 1 (1991): 26–37. http://dx.doi.org/10.1109/65.67857.

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21

Fujioka, M., Y. Ikeda, and M. Norigoe. "Error control criteria in the message transfer part of CCITT Signaling System No.7." IEEE Transactions on Communications 38, no. 9 (1990): 1630–36. http://dx.doi.org/10.1109/26.61406.

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22

Boccaccio, Anna, Anna Menini, and Simone Pifferi. "The cyclic AMP signaling pathway in the rodent main olfactory system." Cell and Tissue Research 383, no. 1 (2021): 429–43. http://dx.doi.org/10.1007/s00441-020-03391-7.

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23

Illes, Peter, Guang-Yin Xu, and Yong Tang. "Purinergic Signaling in the Central Nervous System in Health and Disease." Neuroscience Bulletin 36, no. 11 (2020): 1239–41. http://dx.doi.org/10.1007/s12264-020-00602-7.

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24

Liang, X. H., A. J. Liu, X. F. Pan, F. Chen, and Q. S. Zhang. "Carrier Frequency Recovery for Nyquist and Faster-than-Nyquist Signaling System." Wireless Personal Communications 96, no. 3 (2017): 4661–73. http://dx.doi.org/10.1007/s11277-017-4409-7.

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25

Choi, Bong Dae, Sung Ho Choi, Bara Kim, and Dan Keun Sung. "Analysis of priority queueing system based on thresholds and its application to signaling system no. 7 with congestion control." Computer Networks 32, no. 2 (2000): 149–70. http://dx.doi.org/10.1016/s1389-1286(99)00128-0.

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26

Tretyn, A., M. E. Bossen, and R. E. Kendrick. "Acetylcholine as a signaling system in the swelling of wheat protoplasts." Cell Differentiation and Development 27 (August 1989): 112. http://dx.doi.org/10.1016/0922-3371(89)90354-7.

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27

Adusumilli, Lavanya, Nicola Facchinello, Cathleen Teh та ін. "miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation". Cells 9, № 3 (2020): 711. http://dx.doi.org/10.3390/cells9030711.

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During the development of the central nervous system, the proliferation of neural progenitors and differentiation of neurons and glia are tightly regulated by different transcription factors and signaling cascades, such as the Wnt and Shh pathways. This process takes place in cooperation with several microRNAs, some of which evolutionarily conserved in vertebrates, from teleosts to mammals. We focused our attention on miR-7, as its role in the regulation of cell signaling during neural development is still unclear. Specifically, we used human stem cell cultures and whole zebrafish embryos to s

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28

Otani, Hiroyuki, Fumio Otsuka, Kenichi Inagaki, et al. "Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation." American Journal of Physiology-Renal Physiology 292, no. 5 (2007): F1513—F1525. http://dx.doi.org/10.1152/ajprenal.00402.2006.

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Aldosterone and angiotensin II (ANG II) contribute to the development and progression of renal damage. Here we investigated the effects of bone morphogenetic proteins (BMPs) on renal cell proliferation evoked by aldosterone and ANG II with mouse mesangial cells, which express mineralocorticoid receptors (MR), ANG II type 1 receptors, and BMP signaling molecules. Aldosterone and ANG II stimulated mesangial cell mitosis and activated ERK1/2 and SAPK/JNK signaling. These aldosterone effects were neutralized by the MR antagonist eplerenone and inhibition of transcription or translation, suggesting

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29

Patel, Ekta S., and Lung Ji Chang. "Development of CD4 T cells from Human Hematopoietic stem Cells in a Lentiviral-engineered Stromal Culture (46.15)." Journal of Immunology 182, no. 1_Supplement (2009): 46.15. http://dx.doi.org/10.4049/jimmunol.182.supp.46.15.

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Abstract Hematopoietic precursor/stem cells (HPCs) are progenitors to all functional immune cell lineages. We established a novel stromal cell line expressing (Delta-like 1) DL1, interleukin-7 (IL-7), and FMS-like tyrosine kinase 3 Ligand (Flt3-L) and demonstrated efficient differentiation and expansion of early T cells from adult CD34+ HPCs. However, continuous IL-7 signaling led to the production of immature CD8+ T lymphocytes at the expense of CD4+ T lymphocytes. It is known that the developing double positive T cells shut down IL-7 mediated signaling and require TCR signaling for survival

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30

Zepf, J., and G. Rufa. "Congestion and flow control in Signaling System No. 7—impacts of intelligent networks and new services." IEEE Journal on Selected Areas in Communications 12, no. 3 (1994): 501–9. http://dx.doi.org/10.1109/49.285311.

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31

Zhang, Wenguang, Shengjun Bu, Huasong Bai, et al. "A sensitive biosensor for determination of pathogenic bacteria using aldehyde dehydrogenase signaling system." Analytical and Bioanalytical Chemistry 412, no. 28 (2020): 7955–62. http://dx.doi.org/10.1007/s00216-020-02928-7.

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32

Nautiyal, Manisha, Amy C. Arnold, Mark C. Chappell, and Debra I. Diz. "The Brain Renin-Angiotensin System and Mitochondrial Function: Influence on Blood Pressure and Baroreflex in Transgenic Rat Strains." International Journal of Hypertension 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/136028.

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Mitochondrial dysfunction is implicated in many cardiovascular diseases, including hypertension, and may be associated with an overactive renin-angiotensin system (RAS). Angiotensin (Ang) II, a potent vasoconstrictor hormone of the RAS, also impairs baroreflex and mitochondrial function. Most deleterious cardiovascular actions of Ang II are thought to be mediated by NADPH-oxidase- (NOX-) derived reactive oxygen species (ROS) that may also stimulate mitochondrial oxidant release and alter redox-sensitive signaling pathways in the brain. Within the RAS, the actions of Ang II are counterbalanced

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33

Kulakova, E. S., and A. M. Safarov. "Flowing Sampler System for Surface Water Bodies." Ecology and Industry of Russia 26, no. 7 (2022): 32–37. http://dx.doi.org/10.18412/1816-0395-2022-7-32-37.

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A flowing sampling system using a complex branched pipeline is presented. The system function is ensured by the water supply from the averaging collector to the signaling pigs. The flowing sampling system instalation involves some transport infrastructure, namely bridges. Issues related to the peculiarities of the movement of fluid through the bridge supports, which affect the uneven distribution of pollutants in the monitored area, were investigated.

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34

Shi, Tiezhu, Linli Yao, Ying Han, Piliang Hao, and Pengfei Lu. "Quantitative Phosphoproteomics Reveals System-Wide Phosphorylation Network Altered by Spry in Mouse Mammary Stromal Fibroblasts." International Journal of Molecular Sciences 20, no. 21 (2019): 5400. http://dx.doi.org/10.3390/ijms20215400.

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Understanding the fundamental role of the stroma in normal development and cancer progression has been an emerging focus in recent years. The receptor tyrosine kinase (RTK) signaling pathway has been reported playing critical roles in regulating the normal and cancer microenvironment, but the underlying mechanism is still not very clear. By applying the quantitative phosphoproteomic analysis of Sprouty proteins (SPRYs), generic modulators of RTK signaling and deleted mouse mammary fibroblasts, we quantified a total of 11,215 unique phosphorylation sites. By contrast, 554 phosphorylation sites

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35

Gwathmey, TanYa M., Ebaa M. Alzayadneh, Karl D. Pendergrass, and Mark C. Chappell. "Review: Novel roles of nuclear angiotensin receptors and signaling mechanisms." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 302, no. 5 (2012): R518—R530. http://dx.doi.org/10.1152/ajpregu.00525.2011.

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The renin-angiotensin system (RAS) constitutes an important hormonal system in the physiological regulation of blood pressure. The dysregulation of the RAS is considered a major influence in the development and progression of cardiovascular disease and other pathologies. Indeed, experimental and clinical evidence indicates that blockade of this system with angiotensin-converting enzyme (ACE) inhibitors or angiotensin type 1 receptor (AT1R) antagonists is an effective therapy to attenuate hypertension and diabetic renal injury, and to improve heart failure. Originally defined as a circulating s

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36

Coutinho, Bruna G., Emily Mevers, Amy L. Schaefer, et al. "A plant-responsive bacterial-signaling system senses an ethanolamine derivative." Proceedings of the National Academy of Sciences 115, no. 39 (2018): 9785–90. http://dx.doi.org/10.1073/pnas.1809611115.

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Certain plant-associated Proteobacteria sense their host environment by detecting an unknown plant signal recognized by a member of a LuxR subfamily of transcription factors. This interkingdom communication is important for both mutualistic and pathogenic interactions. The Populus root endophyte Pseudomonas sp. GM79 possesses such a regulator, named PipR. In a previous study we reported that PipR activates an adjacent gene (pipA) coding for a proline iminopeptidase in response to Populus leaf macerates and peptides and that this activation is dependent on a putative ABC-type transporter [Schae

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37

Olofsson, Peder, Mauricio Rosas-Ballina, Sangeeta Chavan, et al. "Long lasting macrophage cytokine suppression by alpha 7 nAChR requires JAK/STAT (138.23)." Journal of Immunology 184, no. 1_Supplement (2010): 138.23. http://dx.doi.org/10.4049/jimmunol.184.supp.138.23.

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Abstract The central nervous system regulates innate immunity reflexively, as action potentials transmitted in the vagus nerve suppress cytokine release during endotoxemia. The mechanism of cytokine release by this neural circuit requires signaling through the alpha 7 nicotinic acetylcholine receptor (a7 nAChR), but the duration of this protection is incompletely understood. Electrical vagus nerve stimulation (VNS) in mice significantly inhibited serum TNF levels during endotoxemia, even when endotoxin was given 2, 24 or 48 h after VNS. This inhibition of TNF was abolished in a7 nAChR deficien

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38

Allen-Sharpley, Michelle R., and Karina S. Cramer. "Coordinated Eph-ephrin signaling guides migration and axon targeting in the avian auditory system." Neural Development 7, no. 1 (2012): 29. http://dx.doi.org/10.1186/1749-8104-7-29.

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39

Hanson, Bonnie J., Justin Wetter, Mark R. Bercher, et al. "A Homogeneous Fluorescent Live-Cell Assay for Measuring 7-Transmembrane Receptor Activity and Agonist Functional Selectivity Through Beta-Arrestin Recruitment." Journal of Biomolecular Screening 14, no. 7 (2009): 798–810. http://dx.doi.org/10.1177/1087057109335260.

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Seven-transmembrane (7TM) receptors play an essential role in the regulation of a wide variety of physiological processes, making them one of the top target classes for pharmaceuticals. 7TM receptor function is mediated and modulated through 2 primary processes: G-protein and beta-arrestin signaling. Classically, it has been recognized that these 2 processes can interact with one another during 7TM receptor desensitization, but it has more recently been recognized that these 2 processes can also act independently of one another and can activate parallel signaling pathways. As such, the methods

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40

Chen, Lai-Jiang, Ran Xu, Hui-Min Yu, Qing Chang, and Jiu-Chang Zhong. "The ACE2/Apelin Signaling, MicroRNAs, and Hypertension." International Journal of Hypertension 2015 (2015): 1–6. http://dx.doi.org/10.1155/2015/896861.

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The renin-angiotensin aldosterone system (RAAS) plays a pivotal role in the development of hypertension. Angiotensin converting enzyme 2 (ACE2), which primarily metabolises angiotensin (Ang) II to generate the beneficial heptapeptide Ang-(1-7), serves as a negative regulator of the RAAS. Apelin is a second catalytic substrate for ACE2 and functions as an inotropic and cardiovascular protective peptide. The physiological effects of Apelin are exerted through binding to its receptor APJ, a seven-transmembrane G protein-coupled receptor that shares significant homology with the Ang II type 1 rece

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41

ZAVOLODKO, Ganna, Daria PAVLOVA, Yana KOLESNIKOVA, and Maksym SUKMANSKYI. "INTERSTAGE OPTIMIZATION OF DATA PROCESSING OF DISTRIBUTED AIRSPACE MONITORING SYSTEMS." ITSynergy, no. 1 (November 30, 2021): 58–65. http://dx.doi.org/10.53920/its-2021-1-7.

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The synthesis and analysis of the data processing optimal structure of survey radar surveillance systems are carried out in the work. By creating a temporary information database of signaling data for the required number of surveillance radar surveillance system, each element of which stores signaling data and quality indicators and parameters of their production, it is possible to carry out interstage optimization of airspace surveillance data processing based on Neumann-Pearson test. It will be possible to formulate the preparation of information messages faster within the current informatio

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42

Maguire, Alanna, Talal Hilal, Xianfeng Chen, Allison C. Rosenthal, and Lisa M. Rimsza. "Enhanced Expression of FGF Signaling in Primary Central Nervous System Lymphoma." Blood 132, Supplement 1 (2018): 2847. http://dx.doi.org/10.1182/blood-2018-99-116416.

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Abstract Introduction: Primary central nervous system lymphoma (PCNSL) is a rare intracranial lymphoma that accounts for less than 1% of all non-Hodgkins lymphomas and 3% of all brain tumors. Histopathologically, approximately 90% of PCNSL cases are categorized as a diffuse large B-Cell lymphoma (DLBCL). DLBCL malignancies are subdivided by Cell of Origin (COO), with the vast majority of PCNSL categorized as non-germinal center B cell (non-GCB) by immunohistochemistry. Gene expression profiling (GEP), however, has shown that immunohistochemically defined non-GCB resolves into two distinct subt

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43

Zheng, Jinji, Xicai Li, Qinqin Wu, and Yuanqin Wang. "A Free-Space Optical Communication System Based on Bipolar Complementary Pulse Width Modulation." Sensors 23, no. 18 (2023): 7988. http://dx.doi.org/10.3390/s23187988.

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In this work, we propose a bipolar complementary pulse width modulation strategy based on the differential signaling system, and the modulation–demodulation methods are introduced in detail. The proposed modulation–demodulation strategy can effectively identify each symbol’s start and end time so that the transmitter and receiver can maintain correct bit synchronization. The system with differential signaling has the advantages of not requiring channel state information and reducing background radiation. To further reduce the noise in the system, a multi-bandpass spectrum noise reduction metho

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44

Dilauro, Marc, and Kevin D. Burns. "Angiotensin-(1-7) and Its Effects in the Kidney." Scientific World JOURNAL 9 (2009): 522–35. http://dx.doi.org/10.1100/tsw.2009.70.

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Angiotensin-(1-7) (Ang-[1-7]) is a heptapeptide member of the renin-angiotensin system (RAS), and acts as a vasodilator and antagonist of angiotensin II (Ang II) in the vasculature. The role of Ang-(1-7) in regulating kidney function is not well understood. Within the kidneys, Ang-(1-7) is generated by angiotensin-converting enzyme 2 (ACE2)–mediated degradation of Ang II, sequential cleavage of the precursor angiotensin I (Ang I) by ACE2 and ACE, or the actions of brush-border membrane peptidases on Ang I. Ang-(1-7) mediates its effects via binding to kidney Mas receptors, although some action

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45

Maire, Magali, Anne Florin, Krisztian Kaszas та ін. "Alteration of Transforming Growth Factor-β Signaling System Expression in Adult Rat Germ Cells with a Chronic Apoptotic Cell Death Process after Fetal Androgen Disruption". Endocrinology 146, № 12 (2005): 5135–43. http://dx.doi.org/10.1210/en.2005-0592.

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In utero exposure to chemicals with antiandrogen activity induces undescended testis, hypospadias, and sub- or infertility. The hypospermatogenesis observed in the adult rat testis exposed in utero to the antiandrogen flutamide has been reported to be a result of a long-term apoptotic cell death process in mature germ cells. However, little if anything is known about the upstream signaling mechanisms controlling this apoptosis. In the present study, we have investigated the possibility that the TGF-β signaling pathway may be at play in this control of the apoptotic germ cell death process. By

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46

Lortie, Michel B., та Thomas W. Moon. "The rainbow trout skeletal muscle β-adrenergic system: characterization and signaling". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 284, № 3 (2003): R689—R697. http://dx.doi.org/10.1152/ajpregu.00512.2002.

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The presence and functionality of β-adrenoceptors (β-ARs) were examined in red (RM) and white muscle (WM) membranes isolated from the rainbow trout Oncorhynchus mykiss. Specific binding assays revealed the presence of a single class of binding sites with similar affinities in both muscle types ( K d in nM: 0.14 ± 0.03 and 0.18 ± 0.03 for RM and WM, respectively) but with a significantly higher number of binding sites in RM compared with WM (Bmax in fmol/mg protein: 3.22 ± 0.11 and 2.60 ± 0.13, respectively). Selective and nonselective β-adrenergic agonists (β-AAs) and antagonists indicated an

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47

Feng, Lei, Mary E. Hatten, and Nathaniel Heintz. "Brain lipid-binding protein (BLBP): A novel signaling system in the developing mammalian CNS." Neuron 12, no. 4 (1994): 895–908. http://dx.doi.org/10.1016/0896-6273(94)90341-7.

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48

Yang, Shih-Hung, Seu-Mei Wang, Jhih-Pu Syu, et al. "Andrographolide Induces Apoptosis of C6 Glioma Cells via the ERK-p53-Caspase 7-PARP Pathway." BioMed Research International 2014 (2014): 1–15. http://dx.doi.org/10.1155/2014/312847.

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Background.Glioma is the most malignant tumor of the central nervous system. Efforts on the development of new chemotherapy are mandatory. Andrographolide (AND), a diterpenoid lactone isolated from theAndrographis paniculata, has been shown to have antitumor activities in several types of cancer cells. Whether AND can exert its antitumor activity in glioblastoma cells remains unknown. This study examined the anticancer effects of AND, bothin vitroandin vivo.Methods.Cell apoptosis was assayed by flow cytometry and nuclear staining. The signaling pathway for AND was determined by western blottin

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49

Senger, Nathalia, Marcos Barrouin Melo, Gabriela Placoná Diniz, Maria José Campagnole-Santos, Robson Augusto Souza Santos та Maria Luiza M. Barreto-Chaves. "Angiotensin-(1–7) reduces cardiac effects of thyroid hormone by GSK3Β/NFATc3 signaling pathway". Clinical Science 132, № 11 (2018): 1117–33. http://dx.doi.org/10.1042/cs20171606.

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Patients with hyperthyroidism exhibit increased risk of development and progression of cardiac diseases. The activation of the renin–angiotensin system (RAS) has been indirectly implicated in these cardiac effects observed in hyperthyroidism. Angiotensin-(1–7) (Ang-(1–7)) has previously been shown to counterbalance pathological effects of angiotensin II (Ang II). The aim of the present study was to investigate the effects of elevated circulating Ang-(1–7) levels on cardiac effects promoted by hyperthyroidism in a transgenic rat (TG) model that constitutively overexpresses an Ang-(1–7)-producin

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50

Durieux, Marcel E. "Halothane Inhibits Signaling through m1 Muscarinic Receptors Expressed in Xenopus Oocytes." Anesthesiology 82, no. 1 (1995): 174–82. http://dx.doi.org/10.1097/00000542-199501000-00022.

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Background Interactions between volatile anesthetics and muscarinic acetylcholine receptors have been studied primarily in binding assays or in functional systems derived from tissues or cells, often containing multiple receptor subtypes. Because interactions with muscarinic signaling systems may explain some effects and side effects of anesthetics and form a model for anesthetic-protein interactions in general, the author studied anesthetic inhibition of muscarinic signaling in an isolated system. Methods mRNA encoding the m1 muscarinic receptor subtype was prepared in vitro and expressed in

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