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1

Chen, L., P. Giannakouros, and E. V. Berkeley. "Are the significant effects really significant?" Human Reproduction 27, no. 11 (2012): 3358. http://dx.doi.org/10.1093/humrep/des240.

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2

Torche, F., and K. Kleinhaus. "Reply: Are the significant effects really significant?" Human Reproduction 27, no. 11 (2012): 3359–60. http://dx.doi.org/10.1093/humrep/des241.

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3

Zhang, Yuan‐Ye, Junjie Yin, Ming Zhou, Zeru Lin, and Qingshun Q. Li. "Adaptive transgenerational effects remain significant." Ecology Letters 23, no. 11 (2020): 1719–20. http://dx.doi.org/10.1111/ele.13589.

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4

&NA;. "Amlodipine has significant antianginal effects." Inpharma Weekly &NA;, no. 784 (1991): 6. http://dx.doi.org/10.2165/00128413-199107840-00017.

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5

Bobinac, Ana, N. Job A. van Exel, Frans F. H. Rutten, and Werner B. F. Brouwer. "Health Effects in Significant Others." Medical Decision Making 31, no. 2 (2010): 292–98. http://dx.doi.org/10.1177/0272989x10374212.

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6

&NA;. "Sirolimus + calcineurin inhibitors: significant adverse effects." Reactions Weekly &NA;, no. 945 (2003): 5. http://dx.doi.org/10.2165/00128415-200309450-00011.

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7

Brody, Eve M., and Barry A. Farber. "Effects of psychotherapy on significant others." Professional Psychology: Research and Practice 20, no. 2 (1989): 116–22. http://dx.doi.org/10.1037/0735-7028.20.2.116.

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8

Kovács, Gyula, Mareike Grotheer, Lisa Münke, Szabolcs Kéri, and Igor Nenadić. "Significant repetition probability effects in schizophrenia." Psychiatry Research: Neuroimaging 290 (August 2019): 22–29. http://dx.doi.org/10.1016/j.pscychresns.2019.05.006.

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9

Ouyang, John F., and Ryan P. A. Bettens. "When are Many-Body Effects Significant?" Journal of Chemical Theory and Computation 12, no. 12 (2016): 5860–67. http://dx.doi.org/10.1021/acs.jctc.6b00864.

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10

Kyriakou, Georgios, Erlend R. M. Davidson, Guowen Peng, et al. "Significant Quantum Effects in Hydrogen Activation." ACS Nano 8, no. 5 (2014): 4827–35. http://dx.doi.org/10.1021/nn500703k.

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11

Davidson, Ernest R. "Qualitatively significant effects of electron correlation." International Journal of Quantum Chemistry 20, S15 (2009): 65–68. http://dx.doi.org/10.1002/qua.560200808.

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12

Lakshmi Sri, S., Saravanan R, Raj Vikram N, Karthikeyan M K, Satya K, and D. Beno Gershon. "Root Resorption during Orthodontic Treatment - A Review on Significant Factors and Treatment Effects." International Journal of Science and Research (IJSR) 10, no. 10 (2021): 259–62. https://doi.org/10.21275/sr211001131124.

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13

Beukes, Eldre Wiida, Alyssa Jade Ulep, Gerhard Andersson, and Vinaya Manchaiah. "The Effects of Tinnitus on Significant Others." Journal of Clinical Medicine 11, no. 5 (2022): 1393. http://dx.doi.org/10.3390/jcm11051393.

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Although chronic conditions could cause third-party disability for significant others (SOs), little is known regarding the impact of tinnitus on SO. This study aimed to identify the effects of tinnitus on SOs. SOs of individuals with tinnitus were invited to participate in this study. SOs completed three open-ended questions focusing on the effects of tinnitus. Individuals with tinnitus completed the Tinnitus Functional Index as a self-reported measure of tinnitus severity. A mixed-methods analysis approach was undertaken. Of the 156 SOs responding, 127 (85%) reported that tinnitus impacted them. The impact surrounded sound adjustments, activity limitations, additional demands, emotional toll, and helplessness. Tinnitus negatively affected the relationship for 92 (58%) due to communication frustrations and growing apart. When asked if tinnitus had any positive effects, 64 (47%) SOs reported positive lifestyle adaptions, personal development, health awareness, and a changed outlook. There was no association between the level of tinnitus severity and SOs reporting that tinnitus had an impact on them individually, their relationships, or those reporting positive experiences. The study highlighted the third-party disability many SOs of individuals with tinnitus experience. The results indicate that SOs may benefit from a shared intervention to help mitigate the negative effects through a better understanding of tinnitus.
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14

Botzman, Maya, and Irit Gat-Viks. "Significant common environmental effects on leukocyte subpopulations." PLOS ONE 13, no. 4 (2018): e0196193. http://dx.doi.org/10.1371/journal.pone.0196193.

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15

Pritschet, Laura, Derek Powell, and Zachary Horne. "Marginally Significant Effects as Evidence for Hypotheses." Psychological Science 27, no. 7 (2016): 1036–42. http://dx.doi.org/10.1177/0956797616645672.

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16

Hurelbrink, Carrie B., Judith M. Spies, and Con Yiannikas. "Significant dermatological side effects of intravenous immunoglobulin." Journal of Clinical Neuroscience 20, no. 8 (2013): 1114–16. http://dx.doi.org/10.1016/j.jocn.2012.10.026.

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17

Hiller, Avram. "Morally Significant Effects of Ordinary Individual Actions." Ethics, Policy & Environment 14, no. 1 (2011): 19–21. http://dx.doi.org/10.1080/21550085.2011.561588.

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18

Langsrud, Øyvind, Marit Risberg Ellekjaer, and Tormod Naes. "Identifying significant effects in fractional factorial experiments." Journal of Chemometrics 8, no. 3 (1994): 205–19. http://dx.doi.org/10.1002/cem.1180080304.

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19

Kapoor, Shailendra. "Emerging Neuroprotective Effects of N-Palmitoylethanolamide Besides Its Significant Antinociceptive Effects." Pain Medicine 14, no. 5 (2013): 773–74. http://dx.doi.org/10.1111/pme.12118.

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20

Davkhar, Somnath Shriram* Dr. Hemant Hiraman Gangurde Anap Sakshi Macchinra Barbade Amol Gangadhar. "Review On Formulation and Evaluation of Beetroot Juice as Prebiotics." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 2612–20. https://doi.org/10.5281/zenodo.14779855.

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Beetroot juice has gained significant attention for its health-promoting properties, including its potential as a functional food supporting gut health. Rich in bioactive compounds such as nitrates and polyphenols, beetroot juice exhibits antioxidant, anti-inflammatory, and vasodilatory effects. Recent studies suggest that beetroot juice may also act as a prebiotic, promoting the growth of beneficial gut microbiota, particularly those involved in nitrate metabolism and short-chain fatty acid production.
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21

Lorah, Julie A. "Interpretation of main effects in the presence of non-significant interaction effects." Quantitative Methods for Psychology 16, no. 1 (2020): 33–45. http://dx.doi.org/10.20982/tqmp.16.1.p033.

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22

Malone, Ashley, and Jayne Price. "The significant effects of childhood cancer on siblings." Cancer Nursing Practice 11, no. 4 (2012): 26–31. http://dx.doi.org/10.7748/cnp2012.05.11.4.26.c9095.

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23

Berg, Steven J., Paul A. Hsieh, and Walter A. Illman. "Estimating Hydraulic Parameters When Poroelastic Effects Are Significant." Ground Water 49, no. 6 (2011): 815–29. http://dx.doi.org/10.1111/j.1745-6584.2010.00781.x.

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24

Albajes-Eizagirre, Anton, Aleix Solanes, and Joaquim Radua. "Meta-analysis of non-statistically significant unreported effects." Statistical Methods in Medical Research 28, no. 12 (2018): 3741–54. http://dx.doi.org/10.1177/0962280218811349.

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Published studies in Medicine (and virtually any other discipline) sometimes report that a difference or correlation did not reach statistical significance but do not report its effect size or any statistic from which the latter may be derived. Unfortunately, meta-analysts should not exclude these studies because their exclusion would bias the meta-analytic outcome, but also they cannot be included as null effect sizes because this strategy is also associated to bias. To overcome this problem, we have developed MetaNSUE, a novel method based on multiple imputations of the censored information. We also provide an R package and an easy-to-use Graphical User Interface for non-R meta-analysts.
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25

Hilberg, Ole, Ulf Simonsen, Roland du Bois, and Elisabeth Bendstrup. "Pirfenidone: significant treatment effects in idiopathic pulmonary fibrosis." Clinical Respiratory Journal 6, no. 3 (2012): 131–43. http://dx.doi.org/10.1111/j.1752-699x.2012.00302.x.

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26

Arnold, Ulrich, and Michael Schöpfel. "Significant stabilization of ribonuclease A by additive effects." FEBS Journal 279, no. 14 (2012): 2508–19. http://dx.doi.org/10.1111/j.1742-4658.2012.08632.x.

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27

Di Russo, Francesco. "Insignificant C1 effects cannot be called ‘marginally significant’." Cognitive Neuroscience 9, no. 1-2 (2017): 70–71. http://dx.doi.org/10.1080/17588928.2017.1386641.

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28

Harbord, Michael G. "Significant anticonvulsant side-effects in children and adolescents." Journal of Clinical Neuroscience 7, no. 3 (2000): 213–16. http://dx.doi.org/10.1054/jocn.1999.0190.

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29

Omran, Huda Mossa, Maryam Ghloom Dashti, and Moiz Bakhiet. "Significant Effects of Smoking Habit on Male Fertility." Bahrain Medical Bulletin 35, no. 2 (2013): 74–77. http://dx.doi.org/10.12816/0000527.

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30

Knudson, Duane. "Significant and meaningful effects in sports biomechanics research." Sports Biomechanics 8, no. 1 (2009): 96–104. http://dx.doi.org/10.1080/14763140802629966.

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31

Langsrud, Øyvind. "Identifying Significant Effects in Fractional Factorial Multiresponse Experiments." Technometrics 43, no. 4 (2001): 415–24. http://dx.doi.org/10.1198/00401700152672500.

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32

Hund, E., A. Aschoff, V. Tronnier, J. Hampl, and S. Kunze. "Nimodipine: Evidence for clinically significant gastrointestinal side-effects." Acta Neurochirurgica 102, no. 1-2 (1990): 73–75. http://dx.doi.org/10.1007/bf01402190.

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33

Ring, Michael E., Gary V. Martin, and Paul E. Fenster. "Clinically Significant Antiplatelet Effects of Calcium-Channel Blockers." Journal of Clinical Pharmacology 26, no. 8 (1986): 719–20. http://dx.doi.org/10.1002/j.1552-4604.1986.tb02981.x.

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34

Waters, C. H. "Fluoxetine and Selegiline – Lack of Significant Interaction." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 21, no. 3 (1994): 259–61. http://dx.doi.org/10.1017/s031716710004124x.

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Abstract:The use of the combination of fluoxetine, an anti-depressant serotonin uptake inhibitor, and selegiline, a monoamine oxidase -B inhibitor, was reviewed in a large population of patients with Parkinson’s disease. All records were reviewed from a Parkinson’s disease clinic to determine how many patients were treated simultaneously with selegiline and fluoxetine. Patient characteristics, duration and dose of treatment, side effects and reasons for discontinuation were noted. Twenty-three patients received both medications at the same time. No additional side effects were noted with the combination therapy that had not already been reported with each medication alone. No serious side effects were found. In this clinic population, fluoxetine and selegiline were used in combination without major side effects, but further observation is warranted.
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35

Ehoniyotan, Olayemi Ibukun, Daniel Eneji Sani, and Dorcas Ropo Abejide. "Effects of salinity stress on the growth performance of two varieties of Kenaf (Hibiscus cannabinus L.)." GSC Biological and Pharmaceutical Sciences 11, no. 1 (2020): 121–26. https://doi.org/10.5281/zenodo.4277023.

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Salinity stress is one of the most serious factors limiting the productivity of agricultural crops with adverse effects on germination, plant vigor and crop yield. This experiment was conducted to determine the effects of salinity stress on HIB 16 and HIB 17 varieties of Kenaf (Hibiscus cannabinus) grown in pots under greenhouse conditions. Salinity treatments of 4 ds/m, 6 ds/m and 8 ds/m were applied for a period of 9 weeks and the physiological changes in the plants were observed. Results revealed that there was no significant difference between the 4 ds/m treatment and control of HIB 16 variety in terms of leaf numbers, stem heights, fresh weights and dry weights throughout the weeks of observation but with an increase in concentration to 6 ds/m and 8 ds/m significant decrease were observed in leaf numbers, stem heights, fresh weights and dry weights. At 4weeks of 8 ds/m treatment the leaves were all withered on HIB 17 variety but there were still leaves on HIB 16 until after the 6th week. The highest recorded height was 65cm and the highest leaf number was 26.67 in control of HIB 16 variety. This work has revealed that kenaf can be grown successfully in moderate saline water. However salt levels of 4 ds/m and above can restrict plant growth and development resulting to significant yield reduction. 
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36

Feng, Ying, Qiushi Wang, Can Shi, Chongdong Liu, and Zhenyu Zhang. "Does Circular RNA Exert Significant Effects in Ovarian Cancer?" Critical Reviews in Eukaryotic Gene Expression 29, no. 2 (2019): 161–70. http://dx.doi.org/10.1615/critreveukaryotgeneexpr.2019025941.

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37

Eruva, Rajasekhar. "Significant effects of temperature on biological properties of ZnO." South Asian Journal of Experimental Biology 9, no. 4 (2019): 157–65. http://dx.doi.org/10.38150/sajeb.9(4).p157-165.

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Zinc oxide (ZnO) is an inorganic compound and it usually appears as a white powder. The powder is widely used as an additive into numerous materials. Inorganic nanoparticles are made by combining organic materials with inorganic materials which forms hybrids and has unique properties. The biological properties of zinc oxide nanoparticles like absorption coefficient, refractive index, concentration, conductivity, pH-values and temperatures were investigated. The diffusion techniques facilitate the measurement of the biological properties of liquids. The results show that absorption coefficient decreases with increasing the thickness of the zinc oxide pellet. The resistivity of the ZnO decreases with increasing the temperature was observed. The concentration of the sample increases conductivity also decreases. Zinc oxide refractive index changes with wavelength. The pH depends on temperature and biological effects were observed at lower concentration and which are playing a vital role in the metabolism of human beings and plant systems. The pH-profiles were measured after 24 h. One-way ANOVA showed significant differences of all tested materials. Variant refractive index can generate resonant cavity that can enhance phase shift of output light and fabricate a variety of optoelectronic device. Materials of high thermal conductivity are widely used in heat sink applications and materials of low thermal conductivity are used as thermal insulation. The biological properties like absorption coefficient, refractive index, concentration, conductivity, pHvalues and temperature were used in many advanced biological, medical and engineering applications such as heat exchangers.
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38

Bilous, O. I., N. V. Bryuzginova, S. P. Sirenko, and Anatoly Ivanovich Fisun. "EFFICIENCY TESTING OF BIOLOGICALLY SIGNIFICANT EFFECTS OF MILLIMETER WAVES." Telecommunications and Radio Engineering 75, no. 8 (2016): 757–62. http://dx.doi.org/10.1615/telecomradeng.v75.i8.80.

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39

Zimmerman, Mark, Janine N. Galione, Naureen Attiullah, et al. "Underrecognition of Clinically Significant Side Effects in Depressed Outpatients." Journal of Clinical Psychiatry 71, no. 04 (2010): 484–90. http://dx.doi.org/10.4088/jcp.08m04978blu.

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40

Yang, Huan, Marlies Hankel, Yujun Zheng, and Antonio J. C. Varandas. "Significant nonadiabatic effects in the C + CH reaction dynamics." Journal of Chemical Physics 135, no. 2 (2011): 024306. http://dx.doi.org/10.1063/1.3599477.

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41

Tanguy, P. A., and R. Lacroix. "A 3D Mold Filling Study with Significant Heat Effects." International Polymer Processing 6, no. 1 (1991): 19–25. http://dx.doi.org/10.3139/217.910019.

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42

Cox, D. R., and Man Yu Wong. "A simple procedure for the selection of significant effects." Journal of the Royal Statistical Society: Series B (Statistical Methodology) 66, no. 2 (2004): 395–400. http://dx.doi.org/10.1111/j.1369-7412.2004.05695.x.

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43

Armero, Oscar E. "Effects of denied hearing loss on the significant other." Hearing Journal 54, no. 5 (2001): 44. http://dx.doi.org/10.1097/01.hj.0000294841.86637.5d.

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44

&NA;. "Ebastine: alleviates symptoms of hayfever without significant adverse effects." Inpharma Weekly &NA;, no. 725 (1990): 6–7. http://dx.doi.org/10.2165/00128413-199007250-00013.

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45

Siontis, G. C., and J. P. Ioannidis. "Risk factors and interventions with statistically significant tiny effects." International Journal of Epidemiology 40, no. 5 (2011): 1292–307. http://dx.doi.org/10.1093/ije/dyr099.

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46

Siegbahn, Per E. M., Margareta R. A. Blomberg, and Shi-Lu Chen. "Significant van der Waals Effects in Transition Metal Complexes." Journal of Chemical Theory and Computation 6, no. 7 (2010): 2040–44. http://dx.doi.org/10.1021/ct100213e.

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47

Chu, Tian-Shu, Ke-Li Han, and George C. Schatz. "Significant Nonadiabatic Effects in the S(1D) + HD Reaction." Journal of Physical Chemistry A 111, no. 34 (2007): 8286–90. http://dx.doi.org/10.1021/jp075173q.

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48

Mostafa, S. M., E. T. Papoutsakis, and W. M. Miller. "Oxygen tension has significant effects on human megakaryocyte maturation." Experimental Hematology 28, no. 12 (2000): 1498. http://dx.doi.org/10.1016/s0301-472x(00)00631-7.

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49

Echeverría, Elena, Frank L. Pasquale, Juan A. Colón Santana, et al. "Significant magneto-resistive effects in boron carbide thin films." Materials Letters 110 (November 2013): 20–23. http://dx.doi.org/10.1016/j.matlet.2013.08.009.

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50

Rufete-Beneite, M., M. Haumann, and M. C. Román-Martínez. "Significant porosity effects in carbon based SILP chiral catalysts." Molecular Catalysis 453 (July 2018): 31–38. http://dx.doi.org/10.1016/j.mcat.2018.04.031.

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