Academic literature on the topic 'Silver Diamine Fluoride'

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Journal articles on the topic "Silver Diamine Fluoride"

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Wright, John Timothy, and Alex White. "Silver Diamine Fluoride." North Carolina Medical Journal 78, no. 6 (November 2017): 394–97. http://dx.doi.org/10.18043/ncm.78.6.394.

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Rodrigues Chibinski, A. C. "Silver diamine fluoride." British Dental Journal 229, no. 6 (September 2020): 328. http://dx.doi.org/10.1038/s41415-020-2189-z.

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Kaur, Harsimran, Rishika ., Nishita Garg, Lumbini Pathivada, Ramakrishna Yeluri, and Sandeep Singh Mayall. "Silver Diamine Fluoride (SDF): The Miracle Fluid." Indian Journal of Dental Education 12, no. 3 (2019): 83–90. http://dx.doi.org/10.21088/ijde.0974.6099.12319.2.

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Rosenblatt, A., T. C. M. Stamford, and R. Niederman. "Silver Diamine Fluoride: A Caries “Silver-Fluoride Bullet”." Journal of Dental Research 88, no. 2 (February 2009): 116–25. http://dx.doi.org/10.1177/0022034508329406.

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Sharwini Baskar, Lakshmi T, and Preetha S. "Awareness Regarding the use of Silver Diamine Fluoride in Dentistry- A Survey." International Journal of Research in Pharmaceutical Sciences 11, SPL3 (October 21, 2020): 1617–25. http://dx.doi.org/10.26452/ijrps.v11ispl3.3485.

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Dental caries is a complex progression due to dietary sugars, bacterial metabolism involving demineralization, and organic degradation. Caries are more prevalent among young children which are mostly untreated due to dental anxiety, behavioural changes, and mainly due to expensive treatment. So innovative approaches are needed to treat caries, especially in children. Arresting caries without restoration is possible by silver diamine fluoride (SDF) which is inexpensive topical medication. Silver diamine fluoride (SDF) is used to treat caries and also prevents future caries development. Silver diamine fluoride (SDF) is also used to treat sensitivity. Before silver diamine fluoride (SDF) silver nitrate and silver varnish were used to treat dental caries. Silver diamine fluoride (SDF) consists of silver, fluoride, ammonia, and water. Silver acts as an antimicrobial agent, fluoride as remineralization, and ammonia stabilizes high concentration. The study setting was an online survey. The number of participants involved was 129. A pre-tested questionnaire was circulated. The data was collected and analyzed using SPSS software. 41.9% of the population participated have heard of silver diamine fluoride (SDF), but 34% of the population are not aware of what it is used to treat. 37.2% of the population is also not aware of the method of application. From the studies, the participants are not aware of silver diamine fluoride (SDF), its uses, and its effectiveness. Oral education should be conducted to create awareness among people.
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Rajakumari, T. N., G. Thiruvenkadam, D. Vinola, and M. Kruthika. "Silver diamine fluoride – A review." Journal of Academy of Dental Education 6 (December 29, 2020): 5–10. http://dx.doi.org/10.25259/jade_3_2020.

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Untreated dental caries remains a challenge in young children and adolescents. Invasive treatments in very young children and children with special health care needs require advanced pharmacological behaviour management strategies. A minimally invasive treatment modality to arrest caries is by application of 38% Silver Diamine Fluoride (SDF). Besides its efficacy to arrest decay, SDF is favoured by its inexpensiveness. This review enlightens the evolution, historical background, mechanism of action, clinical considerations, advantages and disadvantages of Silver Diamine Fluoride.
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Goel, Pallavi, Vikram R, Adarsha M S, and Sudhanva M E. "Silver Diamine Fluoride – A “Silver-fluoride Bullet” for Dental Caries." RGUHS Journal of Dental Sciences 13, no. 4 (2021): 279–82. http://dx.doi.org/10.26715/rjds.13_4_11.

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Dental caries is one of the most prevalent diseases across the globe, affecting all age groups. Various public health measures like water fluoridation have been started to control the spread of caries, especially among children. But these intervention methods are inaccessible to people in some parts of the world. Thus, a product called Silver Diamine Fluoride was introduced, which can help arrest carious lesions at an early stage. It is a beneficial aid for caries arrest in both primary and permanent teeth. Also, can be used for arresting root caries. Thus, the objective of this review article is to discuss about silver diamine fluoride and its diverse uses from both clinician and public health point of view.
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Hasan, Nabil. "Silver Diamine Fluoride in Primary Teeth." Acta Scientific Dental Scienecs 3, no. 8 (July 24, 2019): 77. http://dx.doi.org/10.31080/asds.2019.03.0599.

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Nuvvula, Sivakumar, and Sreekanth Kumar Mallineni. "Silver Diamine Fluoride in Pediatric Dentistry." Journal of South Asian Association of Pediatric Dentistry 2, no. 2 (2019): 73–80. http://dx.doi.org/10.5005/jp-journals-10077-3024.

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Mei, M. L., E. C. M. Lo, and C. H. Chu. "Arresting Dentine Caries with Silver Diamine Fluoride: What’s Behind It?" Journal of Dental Research 97, no. 7 (May 16, 2018): 751–58. http://dx.doi.org/10.1177/0022034518774783.

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Unlike other fluoride-based caries preventive agents, silver diamine fluoride (SDF) can simultaneously prevent and arrest coronal and root dentine caries. The profound clinical success of SDF has drawn many clinicians and researchers to study the mechanism of SDF in arresting dentine caries. This critical review discusses how silver and fluoride contribute to caries arrest, in terms of their effects on bacteria as well as on the mineral and organic content of dentine. Silver interacts with bacterial cell membrane and bacterial enzymes, which can inhibit bacterial growth. Silver can also dope into hydroxyapatite and have an antibacterial effect on silver-doped hydroxyapatite. Furthermore, silver is also a strong inhibitor of cathepsins and inhibits dentine collagen degradation. Early studies proposed that silver hardened caries lesions by forming silver phosphate. However, recent studies found that little silver phosphate remained on the arrested dentine lesion. The principal silver precipitate was silver chloride, which could not contribute to the significant hardening of the arrested lesions. On the other hand, fluoride enhances mineral formation by forming fluorohydroxyapatite with reduced solubility. A significant increase in microhardness occurs with an elevated level of calcium and phosphorus but not silver on the surface layer of the arrested dentine caries lesion following SDF treatment. Fluoride also inhibits matrix metalloproteinases activities and therefore inhibits dentine collagen degradation. The combination of silver and fluoride in an alkaline solution has a synergistic effect in arresting dentine caries. The alkaline property of SDF provides an unfavorable environment for collagen enzyme activation. Understanding the mechanisms of SDF in arresting dentine caries helps clinicians to develop appropriate protocols for the use of SDF in clinical care.
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Dissertations / Theses on the topic "Silver Diamine Fluoride"

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Chu, Chun-hung, and 朱振雄. "Effectiveness of silver diamine fluoride and sodium fluoride varnish in arresting dentine caries." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B30162506.

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Javdan, Nazafarin. "Silver Diamine Fluoride and Oral Health-Related Quality of Life." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4698.

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Purpose: The purpose of this study was to study the association between Silver Diamine Fluoride (SDF) and Oral Health-Related Quality of Life as assessed by “The Early Childhood Oral Health Impact Scale” questionnaire. Methods: Parents of healthy children (ASA I and II) ages 1-5 with early childhood caries with reversible pulpitis who had application of SDF filled out a questionnaire at baseline and again after one month. The questionnaire was designed to evaluate the child’s behavior, physical abilities, pain, temperament, and how well the child gets along with others. Results: Wilcoxon Signed Rank Test was used to determine if responses to various ECOHIS items and the total scores were different between the two time points. Conclusion: Children with dental caries who had application of SDF reported less dental pain, less eating problems, higher quality of sleep and overall higher quality of life at one-month follow up compared with the baseline.
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Fung, Ho-tak Marcus, and 馮浩德. "Effectiveness of silver diamine fluoride solution in arresting early childhood caries." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/209476.

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Early childhood caries (ECC) is the most prevalent oral disease of children worldwide. Epidemiological studies reported that most of the ECC are left untreated. While young children may not be co-operative enough for conventional restorative treatments, silver diamine fluoride (SDF) can be topically applied on tooth surfaces as a cariostatic agent. Previous clinical trials have confirmed that annual application of 38% SDF is effective in arresting dentin caries in preschool children. However, information about the effectiveness of SDF with different combinations of concentration and frequency is still lacking. This information is important for the optimal application of SDF in the future public health programs for caries control. This prospective randomized controlled trial aimed to investigate and compare the effectiveness of 12% and 38% SDF when applied annually or biannually in arresting dentin caries of primary teeth of preschool children for 30 months. The two null hypotheses tested were firstly, there is no difference in effectiveness when SDF is applied at 12% or 38% in arresting dentin caries of preschool children; and secondly, there is no difference in effectiveness when SDF is applied annually or biannually in arresting dentin caries of preschool children. A total of 888 healthy and cooperative K1 children aged 3-4 years with at least one dentin caries surface were recruited and randomized into four treatment groups: Group 1 received annual applications of 12% SDF, Group 2 received biannual applications of 12% SDF, Group 3 received annual applications of 38% SDF, and Group 4 received biannual applications of 38% SDF. Group 3 was assigned as the positive control group. Primary outcome was soft dentin caries surface at baseline that became arrested at the follow-up examinations. Clinical examinations were conducted at the kindergartens every 6 months by the same trained examiner. Parental questionnaires were used to collect the children’s demographic information, oral hygiene related habits, parental satisfaction with children’s dental appearance and dental health at baseline, 18- and 30-month examinations. Adverse effects after treatments including increment of non-vital teeth, complaint about tooth or gingival discomfort, gingival discoloration, and black staining over arrested surfaces were also recorded. A total of 798 children with 3,268 caries surfaces were examined at 30-month follow-up. The dropout rates of the four groups were similar. The respective proportions of arrested surfaces in Group 1 to Group 4 were 48.7%, 54.0%, 60.6%, and 66.9%, respectively (p < 0.001). The two null hypotheses were rejected. Both concentration and frequency were significantly related to treatment effectiveness, but no significant interaction between these two factors was found. The effect size of concentration was much greater than frequency. Other than a higher proportion of black staining in groups receiving 38% SDF treatments, there were no significant differences in adverse effects among the children in the four treatment groups. To conclude, SDF is more effective in arresting dentin caries in primary teeth of preschool children at 38% than 12%, and when applied biannually than annually. Clinical significant improvement in effectiveness can be achieved by increasing its concentration.
published_or_final_version
Dentistry
Doctoral
Doctor of Philosophy
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DePalo, Joseph. "Silver diamine fluoride and interproximal caries progression in the primary dentition." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1560622950433902.

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Mei, Lei, and 梅蕾. "Actions of chlorhexidine and silver diamine fluoride on cariogenic biofilm and root caries." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B44900776.

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Coletti, Brock Jeff. "Clinical Use and Outcomes of Silver Diamine Fluoride in a Hospital Dental Clinic." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1531705574496172.

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Luke, Nicholas L. "A comparison of the antimicrobial efficacy of silver diamine fluoride and silver nitrate: an in vitro study." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5294.

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A COMPARISON OF THE ANTIMICROBIAL EFFICACY OF SILVER DIAMINE FLUORIDE AND SILVER NITRATE: AN IN VITRO STUDY By: Nicholas L Luke, D.D.S. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Dentistry at Virginia Commonwealth University. Virginia Commonwealth University, May 2018 Thesis Advisor: William O. Dahlke Jr., D.M.D. Pediatric Dentistry, Department Chair Purpose: To determine the antimicrobial efficacy of SDF and SN/NaF. Methods: Three bacterial species were combined to create an in vitro biofilm. Treatment was completed with SN, SN/NaF, SDF, SDF½ or untreated (control). Results: The untreated group demonstrated significantly higher growth than all other treatment groups across the study. On the BHI-plates (1-day), there were significant differences between all treatments except SDF and SDF½. On the BHI-plates (3-days), SN/NaF was not significantly different from SDF or SDF½. On the L-MRS-plates (1-day), both SN treatment groups yielded significantly higher growth than the SDF groups. On the L-MRS-plates (3-days), SN yielded significantly higher growth than SN/NaF, SDF, and SDF½. Conclusion: SDF is more effective than SN/NaF, with the exception of BHI-plates (3-days) only and SN/NaF is more effective than SN on primarily S. mutans and L. acidophilus. There is evidence of a possible antimicrobial tolerance of oral bacteria to silver.
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AlNajjar, Reham M. "A comparison of the antimicrobial efficacy of silver diamine fluoride and silver nitrate: an ex vivo study." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5800.

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A comparison of the antimicrobial efficacy of silver diamine fluoride and silver nitrate on various cariogenic bacteria: an ex vivo study By: Reham AlNajjar, D.D.S. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Dentistry at Virginia Commonwealth University. Virginia Commonwealth University, 2019 Thesis Advisor: William Dahlke, D.M.D., Associate Professor and Chair of Pediatric Dentistry, School of Dentistry Purpose: The use of silver-based antimicrobials is an emerging method for the treatment of dental caries. In this study, the authors compare the efficacy of the two most prominent silver- based therapeutics, silver diamine fluoride (SDF) and silver nitrate (AgNO3), on cariogenic and non-cariogenic multispecies biofilms. Currently there is a lack of studies comparing the efficacy of SDF to AgNO3. Methods: Plaque samples from anterior and posterior tooth sites from children presenting both with early childhood caries and caries-free children were collected, pooled, and utilized to create four ex vivo biofilm systems in artificial saliva. SDF and AgNO3 were administered to these biofilms and bacterial survival was quantified and compared to untreated controls. Results: Each of the four pooled sample types was applied to plates coated in artificial saliva + 1% sucrose. Both SDF and AgNO3 were very effective against plaque derived biofilms when compared to untreated biofilms (P0.05) in the potency of each compound. Conclusions: SDF and AgNO3 significantly inhibit ex vivo cariogenic and non-cariogenic biofilms at similar levels.
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Ramirez-Martinez, Guillermo Jose. "ANTIMICROBIAL EFFECTS IN VITRO OF SILVER DIAMINE FLUORIDE AGAINST SELECTED HUMAN RED AND ORANGE COMPLEX PERIODONTAL PATHOGENS." Master's thesis, Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/601896.

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Oral Biology
M.S.
Objectives: Silver diamine fluoride is approved by the United States Food and Drug Administration for intraoral human treatment of tooth hypersensitivity, and it has also been employed world-wide as an emerging method to arrest tooth decay. A 38% silver diamine fluoride formulation, comprised of 25% silver, 5% fluoride, and 8% ammonia as a solvent, is commercially available in the United States. One of the main mechanisms underlying the dental caries arrest potential of silver diamine fluoride is the silver component, which exerts pronounced antimicrobial activity against cariogenic bacteria. Interestingly, studies initiated in the late 1990s demonstrated marked susceptibility of periodontal bacterial pathogens to silver nitrate. However, efforts to develop silver-based, slow-release biodegradable wafers for subgingival placement into periodontal pockets were not commercially successful. At present, no commercial products are available which employ silver ions to combat periodontal bacterial pathogens in periodontal disease treatment. It is not known whether the 38% silver diamine fluoride product commercially available in the United States possesses antimicrobial activity against periodontal bacterial pathogens, and potentially, have application in periodontal therapeutic regimens. As a result, the objective of this study was to test the in vitro antimicrobial effects of silver diamine fluoride on freshly-isolated red and orange complex periodontal pathogens from severe human periodontitis lesions. Methods: Paper point subgingival biofilm samples from 24 adults with severe periodontitis that were to be discarded after microbiological analysis at the Temple University School of Dentistry Oral Microbiology Testing Service Laboratory were secondarily employed in this study. Dilution aliquots from each subgingival specimen were mixed with either 38% or 19% silver diamine fluoride, inoculated onto enriched Brucella blood agar plates, and incubated anaerobically for 7 days at 37°C. Bacterial species growing subsequent to the silver diamine fluoride exposure were considered to be resistant to that concentration of silver diamine fluoride. Total viable counts in silver diamine fluoride-exposed subgingival specimens were quantitated, and established phenotypic criteria employed to identify the following red and orange complex periodontal pathogens: Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia/nigrescens, Parvimonas micra, Campylobacter rectus, Fusobacterium nucleatum group species, and Streptococcus constellatus. Other cultivable isolates recovered from silver diamine fluoride-exposed subgingival specimens were identified using matrix-assisted laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometry and Bruker MALDI Biotyper analytic software. Subgingival sample dilution aliquots not exposed to silver diamine fluoride were similarly processed as controls for comparison with silver diamine fluoride-exposed specimens Paired t-tests compared mean total subgingival viable counts, and mean total subgingival proportions of the evaluated anaerobic red and orange complex periodontal pathogens per patient, between subgingival biofilm samples exposed and not exposed in vitro to 38% or 19% silver diamine fluoride, with a P-value of < 0.05 required for statistical significance. Results: Subgingival specimens exposed in vitro to either 38% or 19% silver diamine fluoride yielded significantly lower total subgingival viable counts per patient than those not exposed to silver diamine fluoride (P < 0.001, paired t-test), with no statistically significant differences found between 38% and 19% silver diamine fluoride exposures (P = 0.370, paired t-test). All evaluated red and orange complex periodontal pathogens were suppressed below detection levels in 21 (87.5%) of subgingival samples after in vitro exposure to 38% silver diamine fluoride. Three other patient specimens treated with 38% silver diamine fluoride each had persistence of P. micra. Similarly, 21 (87.5%) of subgingival specimens also were culture-negative for red and orange complex periodontal pathogens after 19% silver diamine fluoride exposure, with two other patient samples showing persistence of P. micra, and a third sample persistence of S. constellatus. Total subgingival proportions of red and orange complex periodontal pathogens averaged 0.6% per patient in subgingival specimens exposed in vitro to 38% silver diamine fluoride, and 0.5% per patient in those exposed to 19% silver diamine fluoride, which were both significantly lower than 25.9% mean proportions detected in subgingival biofilms not exposed to silver diamine fluoride (P < 0.0001, paired t-test). No statistically significant differences were found between 38% and 19% silver diamine fluoride relative to suppression of total red and orange complex periodontal pathogen proportions (P = 0.345, paired t-test). Various Streptococcus species, particularly Streptococcus oralis, were the most frequently recovered microorganisms in subgingival biofilm specimens after exposure to both 38% and 19% silver diamine fluoride, indicative of their in vitro resistance to silver diamine fluoride. Conclusions: Silver diamine fluoride demonstrated substantial antimicrobial activity against fresh clinical isolates of red and orange complex periodontal pathogens, and total viable counts, in subgingival biofilm specimens from severe periodontitis patients, with no statistically significant differences found between silver diamine fluoride concentrations of 38% and 19%. The dramatic in vitro suppression of red and orange complex periodontal pathogens in subgingival biofilm specimens by silver diamine fluoride, along with its selection of silver diamine fluoride-resistant species of Streptococcus that are associated with periodontal health, suggests a new therapeutic use for silver diamine fluoride in the management of human periodontal infections.
Temple University--Theses
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Pizano, Jessica M. "Opinions and Current Practices of General Dentists, Pediatric Dentists, and Pediatricians of Ohio Regarding Silver Diamine Fluoride." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1499878834976596.

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Book chapters on the topic "Silver Diamine Fluoride"

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Cláudia Rodrigues Chibinski, Ana. "The Use of Silver Diamine Fluoride in Pediatric Dentistry." In Dental Caries [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.93518.

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Huang, Wei-Te, Saroash Shahid, and Paul Anderson. "Applications of silver diamine fluoride in management of dental caries." In Advanced Dental Biomaterials, 675–99. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-08-102476-8.00023-2.

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Singhania, Shreepriya, Nandlal Bhojraj, and Raghavendra Shanbhog. "Is Silver Diamine Fluoride Really a Magic Alternative in Pediatric Caries Management? : An Advanced Clinical Approach." In Recent Developments in Medicine and Medical Research Vol. 10, 120–28. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/rdmmr/v10/4794f.

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Conference papers on the topic "Silver Diamine Fluoride"

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Abdelaziz, Marwa, Daniel Fried, Nai-Yuan N. Chang, V. Yang, William A. Fried, Jong Seto, and C. Darling. "Monitoring silver diamine fluoride application with optical coherence tomography." In Lasers in Dentistry XXVII, edited by Peter Rechmann and Daniel Fried. SPIE, 2021. http://dx.doi.org/10.1117/12.2584901.

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Andriany, Poppy, Sondang Pintauli, Rahayu Lubis, and Anton Rahardjo. "Topical Silver Diamine Fluoride 38% for Arresting Dentine Caries Active in Dental Clinic." In 1st Aceh International Dental Meeting (AIDEM 2019), Oral Health International Conference On Art, Nature And Material Science Development 2019. Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/ahsr.k.210201.016.

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Darwita, Risqa Rina, Faradina Siti Zahra, Irwina Nuryanti Husna, Melissa Adiatman, and Gita Ariffa Sjarkawi. "The effectiveness of silver diamine fluoride in inhibiting dentine caries activity on primary teeth." In THE 5TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the 5th International Symposium of Biomedical Engineering (ISBE) 2020. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0047843.

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Chray, Mengkheng, Shunhour Khorn, Sreykhouch Da, Bathsheba Turton, and Callum Durward. "Pilot evaluation of the therapeutic effect of Silver Diamine Fluoride (SDF) in Arresting dental caries in the primary teeth of Cambodian slum children." In 11th International Dentistry Scientific Meeting (IDSM 2017). Paris, France: Atlantis Press, 2018. http://dx.doi.org/10.2991/idsm-17.2018.17.

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