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1

RANJINI, R. "Biological activity spectra of the main phytochemicals of Silybum marianum L. Gaertn. by in silico study." Journal of Medicinal and Aromatic Plant Sciences 45, no. 1 (2023): 38–45. http://dx.doi.org/10.62029/jmaps.v45i1.ranjini.

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The main objective of bioinformatics is to augment the perception of biological data. Bioinformatics gains information from computer analysis of biological practices. Biologically active principles have both pharmaceutical and adverse effects on the organisms. PASS (Prediction of Activity Spectra for Substances) software is used to estimate the general efficacy and safety of the phytochemicals. PASS simultaneously predicts several hundreds of biological activities of natural and synthetic chemical compounds. The average precision of prediction is about 90%. The extract from the seed of Silybum
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2

O.M., Shevchuk, Ahurova I.V., and Kokhan T.P. "Allelopatic activity of soil in the Echinacea purpurea (L.) Moench and Silybum marianum (L.) Gaertn. rizosphere." Plant Introduction 52 (December 1, 2011): 67–71. https://doi.org/10.5281/zenodo.2544358.

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Allelopatic activity of soil in the <em>Echinacea purpurea</em> (L.) Moench and <em>Silybum marianum</em> (L.) Gaertn is investigated. It is determined that the both species rhizospheric soil has high allelopathic activity. <em>Silybum marianum</em>&rsquo;s soil inhibits the development of the seedlings <em>Agropyron pectinatum</em> (M. Bieb.) Beauv. and is neutral for <em>Festuca regeliana</em> Pavl. It is shown growth stimulation of the seedlings <em>Agropyron pectinatum</em> and <em>Festuca regeliana</em> on the rizospheric soil of <em>Echinacea purpurea </em>that is shown expediency of tha
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3

Saybel, O. L., E. A. Konyaeva, O. Y. Kulyak, V. N. Dul, O. M. Tsybikova, and B. D. Tsydypov. "QUALITY ASSESSMENT OF SILYBUM MARIANUM FRUITS GROWN IN THE REPUBLIC OF BURYATIA." PROBLEMS OF BIOLOGICAL, MEDICAL AND PHARMACEUTICAL CHEMISTRY 27, no. 3 (2024): 30–34. http://dx.doi.org/10.29296/25877313-2024-03-05.

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Introduction. Medicines of plant origin are widely used in the complex therapy of various diseases. Among the medicines of plant origin used for the treatment of chronic liver diseases, the most popular are preparations based on Silybum marianum (L.) Gaertn.). The aim of this work was to Silybum marianum fruits to evaluate the possibility of obtaining raw materials of pharmacopoeial quality in the dry-steppe zone of the Republic of Buryatia. Material and methods. The object of the study was Silybum marianum fruits of the varieties Debut and Start, obtained from experimental fields in Ivolginsk
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4

Wang, Yubin, Lingjie Li, Jinbei He, and Baojiang Sun. "Extract of Silybum marianum (L.) Gaertn Leaves as a Novel Green Corrosion Inhibitor for Carbon Steel in Acidic Solution." Materials 17, no. 19 (2024): 4794. http://dx.doi.org/10.3390/ma17194794.

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In this work, leaves of Silybum marianum (L.) Gaertn were extracted by a one-step extraction method using ethanol as a solvent, and the Silybum marianum (L.) Gaertn extract (SMGE) was firstly employed as a green corrosion inhibitor for carbon steel in 0.5 mol/L H2SO4. The corrosion inhibition performance was studied using weight loss and electrochemical methods, and the anti-corrosion mechanism of SMGE is further analyzed through some surface characterizations and theoretical calculations. The results indicate that SMGE can act as a mixed-type corrosion inhibitor and possess superior corrosion
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5

Abdraimova, K. Yu, A. O. Karimbayeva, D. R. Rasbergenova, and G. I. Saparniyazova. "Technology of Cultivation of Silybum marianum Gaertn. L. (Milk Thistle)." American Journal Of Agriculture And Horticulture Innovations 5, no. 3 (2025): 20–23. https://doi.org/10.37547/ajahi/volume05issue03-06.

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This article provides an in-depth analysis of the cultivation technology of Silybum marianum Gaertn. L. (MilkThistle), a medicinal plant valued for its hepatoprotective properties, primarily attributed to its bioactive compound, silymarin. The article explores essential aspects of milk thistle cultivation, including soil and climate requirements, sowing practices, fertilization, irrigation, pest and disease management, as well as harvesting and post-harvest processing. Additionally, it highlights modern biotechnological advances, such as in vitro and hairy root culture techniques, that can com
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6

NURZYŃSKA-WIERDAK, RENATA, JAN DYDUCH, AGNIESZKA SAWICKA, HELENA ŁABUDA, and HALINA BUCZKOWSKA. "Ostropest plamisty (Silybum marianum [L .] Gaertn.) – fitochemia i efekty terapeutyczne." Annales Horticulturae 28, no. 4 (2018): 15–32. http://dx.doi.org/10.24326/ah.2018.4.2.

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Ostropest plamisty (Silybum marianum (L.) Gaertn.) jest obecnie jednym z ważniejszych gatunków roślin leczniczych uprawianym na plantacjach zielarskich. Surowcem zielarskim ostropestu jest owoc (Silybi mariani fructus) zawierający kompleks flawonolignanów określanych jako sylimaryna. Sylimaryna wykazuje działanie ochronne i regenerujące względem uszkodzonych komórek wątroby. Działanie ochronne sylimaryny wiąże się z jej aktywnością antyoksydacyjną, przeciwzapalną, przeciwwirusową, a także odtruwającą. Związek ten wpływa również na syntezę RNA i DNA. Sylimaryna jest obecnie szeroko stosowana ja
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7

Mirzayev, Muhammadumar Akbarali Ôgli Sultanova Gulbahor Abdijalolovna. "GROWTH AND DEVELOPMENT OF SILYBUM MARIANUM (L) GAERTN PLANT." YOSH OLIMLAR ILMIY-AMALIY KONFERENSIYASI 2, no. 03 (2023): 99–100. https://doi.org/10.5281/zenodo.7952177.

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Silybum marianum (L.) Gaertn is a versatile plant, found on all continents and adapted to different soil and environmental conditions. &quot;) is the only reliable source of silymarin, which, given its recognized therapeutic effects and many current and potential uses, has led to significant rediscovery and improvement of crop yields in plants. &nbsp;
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8

Louafi, Boutaina, Chaimae Slimani, Aymane Bessi, Chaimae Rais, Lahsen El Ghadraoui, and Meryem Benjelloun. "Ethnobotanical survey of Silybum marianum L. Gaertn in the Ouezzane region (northwestern Morocco): Knowledge and use of the plant." BIO Web of Conferences 115 (2024): 06004. http://dx.doi.org/10.1051/bioconf/202411506004.

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Silybum marianum L. Gaertn is a spontaneous plant whose medicinal properties have been used for over two thousand years. This study aims to clarify the understanding and utilisation of S. marianum by the rural and urban populations of Ouezzane region in Morocco, in order to assess the level of recognition and exploitation of this plant. An ethnobotanical survey in this region involved a sample of 140 individuals. Survey results are analyzed using SPSS. The survey results have revealed a significantly limited level of appreciation for S. marianum. Through the use of chi-square statistical tests
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9

Ciocarlan, Alexandru, Ion Dragalin, Aculina Aricu, Nina Ciocarlan, Cristina Stavarache, and Mariana Deleanu. "Chromatographic Analysis of Silybum Marianum (L.) Gaertn. Fatty Oil." Chemistry Journal of Moldova 13, no. 1 (2018): 63–68. http://dx.doi.org/10.19261/cjm.2018.484.

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10

Mirzayev, Muhammadumar Akbarali o'gli Sultanova Gulbahor Abdijalolovna Karimov Farxod Isomiddinovich. "SILYBUM MARIANUM (L) GAERTN O'SIMLIGINING TADQIQOT JARAYONIDA BAJARILGAN ISHLAR." EURASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES 3, no. 6 (2023): 41–44. https://doi.org/10.5281/zenodo.8068337.

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Yer yuzida dorivor o&lsquo;simliklarning 10-12 ming turi bo&lsquo;lib, shu jumladan 1000 dan ortiq o&lsquo;simlik turlarining kimyoviy, farmokologik va dorivorlik xossalari tekshrilgan. Sintetik preparatlarni uzoq muddat qabul qilish inson organizmida turli ko&lsquo;ngilsiz holatlarni keltirib chiqaradi. Dorivor o&lsquo;simliklarning tabiiy xom-ashyo vositalaridan tayyorlangan tabiiy preparatlar organizmga sekin ta&rsquo;sir etsa ham salbiy oqibatlari deyarli kuzatilmaydi.
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11

Lv, Yongkun, Song Gao, Sha Xu, Guocheng Du, Jingwen Zhou, and Jian Chen. "Spatial organization of silybin biosynthesis in milk thistle [ Silybum marianum (L.) Gaertn]." Plant Journal 92, no. 6 (2017): 995–1004. http://dx.doi.org/10.1111/tpj.13736.

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12

Kumar, Kiran, Pradeep, Simran Kirti, and Altamash Ali Daudi. "Original article Phytochemical analysis and antioxidants activity of Silybum marianum (L.) Gaertn." Annals of Phytomedicine: An International Journal 8, no. 1 (2019): 127–34. http://dx.doi.org/10.21276/ap.2019.8.1.16.

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13

FAHMY, WALEED GAMAL EL DIN, SAHAR RAMADAN ABDELHADY, SAMIR MAHMOUD METWALY, and FATMA ALI AHMED. "Effect of ethanolic extract of Silybum marianum L. Gaertn. on lipid peroxidation inhibition and microbial count in minced beef." Romanian Biotechnological Letters 26, no. 4 (2021): 2773–78. http://dx.doi.org/10.25083/rbl/26.4/2773-2778.

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The present research was carried out for two main targets, the first one is phytochemical and biological screening of the aerial parts of Silybum marianum. The second one is the possibility of using Silybum marianum ethanolic extract as natural preservative for extending minced beef shelf-life during refrigeration and frozen storage. The chemical analysis of dry matter revealed that total ash content was 13.04% of D.M, crude fibers, total phenolic compounds, total flavonoids and total tannins were (24.59%, 9.16%, 0.84% and (0.08%), respectively. The highest values of antioxidant activity were
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14

COȘERAN, Mihaela Anca, Daniela BENEDEC, Daniela HANGANU, et al. "Impact of Organic Fertilization on Polyphenolic Content in Milk Thistle (Silybum marianum L. Gaertn.) Genotypes from Romania." Hop and Medicinal Plants 32, no. 1-2 (2024): 225–35. https://doi.org/10.15835/hpm.v32i1-2.15027.

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Silybum marianum (L.) Gaertn. is a major source of active principles, but also a plant that perfectly meets the needs of sustainable agriculture. The present research analyses the efficiency of organic fertilization for the increase of active principles in the fruits of milk thistle cultivated in the area of Măciuca, southern Vâlcea County, Romania. The aim of this work was the spectrophotometric determination of the total polyphenols content (TPC) of five different genotypes of milk thistle (Prahova, a1; Secuieni, a2; Iași, a3; Dacia Plant, a4; Brașov, a5) both unfertilized, and treated with
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15

Jobst, Detmar, Karin Kraft, Björn Feistel, and Robert Fürst. "Silymarin-Extrakt aus Silybum marianum (L.) Gaertn. gegen alimentär-toxische Leberschäden?" Zeitschrift für Phytotherapie 41, no. 01 (2020): 32–36. http://dx.doi.org/10.1055/a-1015-5202.

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Die nichtalkoholische Fettlebererkrankung (NAFLD) zählt zu den häufigsten Lebererkrankungen weltweit. Wesentliche Risikofaktoren sind eine durch Fehl- und Überernährung hervorgerufene Adipositas, Fettstoffwechselstörungen und Insulinresistenz. Silymarin-Präparate zeigten hier in jüngeren Studien uneinheitliche Ergebnisse.
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16

Gasimova, Shakhla Adalet, El'dar Novruz Novruzov та Naiba Pirverdi Mehdiyeva. "ИЗУЧЕНИЕ ХИМИЧЕСКОГО СОСТАВА ЖИРНОГО МАСЛА ИЗ СЕМЯН SILYBUM MARIANUM (L.) GAERTN." chemistry of plant raw material, № 3 (15 березня 2017): 107. http://dx.doi.org/10.14258/jcprm.2017031585.

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17

Karkanis, Anestis, Dimitrios Bilalis, and Aspasia Efthimiadou. "Cultivation of milk thistle (Silybum marianum L. Gaertn.), a medicinal weed." Industrial Crops and Products 34, no. 1 (2011): 825–30. http://dx.doi.org/10.1016/j.indcrop.2011.03.027.

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18

КОЗЫКЕЕВА, Р. А., К. К. ОРЫНБАСАРОВА, Ш. К. МАУЖАН та Р. А. КОЗЫКЕЕВА. "ШҰБАР АЛАТІКЕН (SILYBUM MARIANUM L. GAERTN.) – ДӘРІЛІК ӨСІМДІГІНІҢ КУЛЬТИВАЦИЯСЫН ҰЙЫМДАСТЫРУ ЖОЛДАРЫ". Farmaciâ Kazahstana, № 6 (13 січня 2024): 250–59. http://dx.doi.org/10.53511/pharmkaz.2024.98.54.033.

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Шұбар алатікен (Silybum marianum L. Gaertn.) бауыр ауруларын емдеуге арналған дәрілік өсімдік. Оның емдік қасиеттері силимариннің, үш флавонолигнанның (силибин, силидианин және силикристин) қоспасының болуына байланысты. Тұқымдарында силимариннің ең көп мөлшері бар, бірақ бүкіл өсімдік бөліктері медицинада қолданылады. Шұбар алатікен кез келген топырақ түрлерінде өсе алады, құмды топырақтан сазға дейін. Шұбар алатікеннің тұқымдары тікелей топыраққа себіледі. Егіс күзде және көктемде жүзеге асырылады, ал арықтар арасындағы қашықтық әдетте 40-75 см, қатардағы өсімдіктер арасындағы қашықтық 20-30
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19

Rosińska, Agnieszka, Magdalena Jarosz, Dorota Szopińska, Hanna Dorna, and Krystyna Tylkowska. "Comparison of methods for detecting fungi in Silybum marianum (L.) Gaertn. seeds." Folia Horticulturae 25, no. 2 (2013): 107–15. http://dx.doi.org/10.2478/fhort-2013-0012.

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ABSTRACT Milk thistle (Silybum marianum (L.) Gaertn.) is one of the most important medicinal plants. The fungi infesting its seeds may negatively influence their germination and health-promoting properties. However, there is no standard method for S. marianum seed health testing. The aim of this study was to find a suitable method for the detection and identification of fungi in/on milk thistle seeds. The following tests were used: deep-freeze blotter test, blotter test with an addition of mannitol, blotter test with an addition of polyethylene glycol, agar test on potato-dextrose agar (PDA),
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20

Martinelli, Tommaso. "Plant morphology, vegetative biomass composition and energy content of three different Silybum marianum accessions." Acta Scientiarum Polonorum Hortorum Cultus 19, no. 6 (2020): 71–78. http://dx.doi.org/10.24326/asphc.2020.6.6.

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Silybum marianum (L.) Gaertn. (milk thistle) is plant species that has been utilized principally for medicinal purposes for more than 2000 years. Recently it was proposed for biomass production in marginal environments, but vegetative biomass compositional analyses had not been available so far. The study of plant morphology and biomass composition was conducted on three different S. marianum accessions grown under open field conditions. The results indicate that plant morphological traits show major differences between accessions: this suggests that the available natural variability can be fu
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21

Egushova, Elena, and Irina Reznichenko. "PROSPECTS EVALUATION OF USING SILYBUM MARIANUM (L.) GAERTN IN THE OF SPECIALIZED FLOUR PRODUCTS COMPOSITION." Bulletin of KSAU, no. 8 (January 29, 2025): 194–202. https://doi.org/10.36718/1819-4036-2023-8-194-202.

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The purpose of the study is to develop and evaluate the quality of butter biscuits with the addition of milk thistle fruit meal. Objectives: to study the biological value of milk thistle and the features of its use in flour confectionery products, to determine the rational dosage of milk thistle meal in the recipe for butter biscuits, to assess the quality by organoleptic and physico-chemical indicators, to determine the nutritional value and specialized focus of the resulting product. Objects - model samples of butter biscuits with the addition of milk thistle meal (5; 7.5; 10; 12.5; 15%). Fo
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22

Shah, Muzamil, Hasnain Jan, Samantha Drouet, et al. "Chitosan Elicitation Impacts Flavonolignan Biosynthesis in Silybum marianum (L.) Gaertn Cell Suspension and Enhances Antioxidant and Anti-Inflammatory Activities of Cell Extracts." Molecules 26, no. 4 (2021): 791. http://dx.doi.org/10.3390/molecules26040791.

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Silybum marianum (L.) Gaertn is a rich source of antioxidants and anti-inflammatory flavonolignans with great potential for use in pharmaceutical and cosmetic products. Its biotechnological production using in vitro culture system has been proposed. Chitosan is a well-known elicitor that strongly affects both secondary metabolites and biomass production by plants. The effect of chitosan on S. marianum cell suspension is not known yet. In the present study, suspension cultures of S. marianum were exploited for their in vitro potential to produce bioactive flavonolignans in the presence of chito
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23

Safrankova, Ivana, Kolackova P, and Rutivckova G. "The pathogen of Milk Thistle (Silybum marianum (L.) Gaertn.) in the Czech Republic." JOURNAL OF ADVANCES IN AGRICULTURE 5, no. 1 (2015): 538–44. http://dx.doi.org/10.24297/jaa.v5i1.4264.

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Milk thistle is grown in the Czech Republic as a medicinal herb; silymarin is isolated from its achenes and used for the production of liver and gallbladder medicine. The quality and content of the active compound is influenced not only by environmental factors, but also by pests and pathogens. The occurrence of pests of milk thistle variety Silyb was observed in two localities during the years 2011 2013. In the year 2011 the mycoflora of seeds of four milk thistle varieties was determined. Representatives of 15 species were isolated from the seeds, most of them saprophytic. 21 fungal species
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24

Martinelli, Tommaso. "CROSSING METHOD FOR THE FURTHER GENETIC IMPROVEMENT OF Silybum marianum (L.) Gaertn." Acta Scientiarum Polonorum Hortorum Cultus 17, no. 3 (2018): 101–8. http://dx.doi.org/10.24326/asphc.2018.3.10.

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25

Marmouzi, Ilias, Abdelhakim Bouyahya, Shahira M. Ezzat, Meryem El Jemli, and Mourad Kharbach. "The food plant Silybum marianum (L.) Gaertn.: Phytochemistry, Ethnopharmacology and clinical evidence." Journal of Ethnopharmacology 265 (January 2021): 113303. http://dx.doi.org/10.1016/j.jep.2020.113303.

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26

Milagres, Eliana Alfenas Nogueira, Berdj A. Meguerian, Vania Santos Carvalho, Valéria Lobato, Liziene de Souza Arruda, and Maria Angélica Fiut. "Eficácia das plantas medicinais Cynara scolymus L. e Silybum marianum (L.) Gaertn em relação ao dano hepático: um estudo de revisão." VITTALLE - Revista de Ciências da Saúde 32, no. 3 (2020): 187–201. http://dx.doi.org/10.14295/vittalle.v32i3.11229.

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As plantas medicinais têm sido utilizadas como fonte alternativa no tratamento de doenças hepáticas, cabendo destacar a Alcachofra (Cynara scolymus L.) e o Cardo mariano (Silybum marianum), que atualmente vêm apresentando evidências de efeitos hepatoprotetores. O presente artigo tem como objetivo buscar evidências científicas acerca da efetividade hepatoprotetora destas plantas. Trata-se de revisão de literatura com seleção criteriosa da produção científica das plantas medicinais mencionadas acima, os quais foram selecionados 19 artigos que preencheram os critérios estabelecidos. Para tal fora
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Абдурахимов, У. К. "МАСЛИЧНОСТЬ И ВИТАМИННЫЙ СОСТАВ СОРТОВ РАСТОРОПШИ ПЯТНИСТОЙ (SILYBUM MARIANUM (L) GAERTN.) ВОЗДЕЛЫВАЕМЫХ В ПОЧВЕННО-КЛИМАТИЧЕСКИХ УСЛОВИЯХ ХОРЕЗМСКОЙ ОБЛАСТИ". 2024-yil 4-son (2024/4) OZIQ-OVQAT XAVFSIZLIGI: MILLIY VA GLOBAL MUAMMOLAR 4, № 138/4 (2024): 4–8. https://doi.org/10.59251/2181-3973.2024.v4.138.4.3117.

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В данной статье приводятся сведения о масличности и витаминном составе сортов расторопши пятнистой (Silybum marianum (L.) Gaertn.). На основании проведенных исследований выявлено что, наибольшее содержание масло было обнаружено у сорта Дебют (25,5%). Самая низкая содержание масла наблюдалась у сорта Самарянка (19,5%). Выход масла у сортов Панацея – 272,2 кг/га; у сорта Дебют – 323,7 кг/га; у сорта Самарянка – 271,6 кг/га и у сорта Старт – 258,6 кг/га. Изходя из результатов исследований и отмеченными биохимическими особенностями и сортовыми различиями расторопши пятнистой, доказана возможность
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28

Pospielova, Ganna, Sergii Pospielov, and Natalia Nechiporenko. "EVALUATION OF THE QUALITY OF MILK THISTLE SEED." Grail of Science, no. 29 (July 18, 2023): 147–49. http://dx.doi.org/10.36074/grail-of-science.07.07.2023.022.

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The results of phytoexamination of the seeds of milk thistle (Silybum marianum (L.) Gaertn.), which were grown in the Poltava region (Ukraine), are presented. Indicators of seed quality, degree of infection and species composition of pathogenic microorganisms were studied. 7 species of fungi have been identified, which according to classification belong to two classes: Deuteromycetes (species of the genera Fusarium, Alternaria, Botrytis, Sordariomycetes) and Zygomycetes (representatives of the genus Mucor). Fungi from the genera Alternaria and Mucor predominated among the detected micromycetes
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29

de Freitas, Jessica Alves, Aline Boveto Santamarina, José Pinhata Otoch, and Ana Flávia Marçal Pessoa. "Silymarin: A Natural Compound for Obesity Management." Obesities 4, no. 3 (2024): 292–313. http://dx.doi.org/10.3390/obesities4030024.

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Silybum marianum (L.) Gaertn, commonly known as milk thistle, is an herbal medicine rich in silymarin, a bioflavonoid complex. Historically, silymarin was used for treating liver diseases, but recent studies highlight silymarin’s potential for obesity management. This narrative review aims to provide an in-depth examination of the existing knowledge of Silybum marianum (L.) and its secondary compounds concerning obesity and associated comorbidities, summarizing data from in vitro, preclinical, and clinical studies. Obesity is a significant public health issue, exacerbated during the COVID-19 p
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30

Ivanov, V., and M. Pavlova. "Comparative study of the antioxidant properties of silymarin and milk thistle extracts." Trakia Journal of Sciences 19, no. 1 (2021): 1–6. http://dx.doi.org/10.15547/tjs.2021.01.001.

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Purpose: Milk thistle (Silybum marianum (L.) Gaertn) has been used for centuries as a natural remedy for liver and gall bladder / biliary tract diseases. Silymarin is the purified and standardized extract from milk thistle seeds. The purpose of the present study is to present a comparative analysis of the total phenolic substances content and the antioxidant effect of silymarin and three different types of Silybum marianum extracts (i.e. ethanol extract, water extract and lyophilized extract). Methods: Total phenolic and flavonoid content of extracts was analysed and the antioxidant activity w
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Рамазанов, А. Ш., and Ш. А. Балаева. "Extraction of Fatty Oil from Milk Thistle Fruits with Supercritical Carbon Dioxide." Сверхкритические Флюиды: Теория и Практика 15, no. 4(4) (2021): 49–58. http://dx.doi.org/10.34984/scftp.2020.15.4.004.

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Расторопша пятнистая [Silybum marianum (L.) Gaertn], произрастающая в Республике Дагестан, является перспективным сырьем для получения лекарственных препаратов широкого спектра действия. Масло из плодов расторопши пятнистой, как источник высших полиненасыщенных карбоновых кислот, обладает противовоспалительным, ранозаживляющим, регенерирующим и антиоксидантным действием. Процесс сверхкритической флюидной экстракции диоксидом углерода жирного масла из плодов расторопши пятнистой оптимизирован с использованием полнофакторного рототабельного униформ-плана второго порядка. Проведена оценка влияния
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Jan, Hammad Ahmad, Igor Šurina, Ahmed S. Al-Fatesh, Abdulaziz M. Almutlaq, Sher Wali, and Anton Lisý. "Biodiesel Synthesis from Milk Thistle (Silybum marianum (L.) Gaertn.) Seed Oil using ZnO Nanoparticles as a Catalyst." Energies 15, no. 20 (2022): 7818. http://dx.doi.org/10.3390/en15207818.

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Biodiesel is considered valuable to reduce dependency on petrofuels. This work aimed to synthesize biodiesel from Silybum marianum using synthesized ZnO nanoparticles as a catalyst. The synthesized ZnO nanoparticles were examined by scanning electron microscopy and X-ray diffraction for confirmation. The synthesized biodiesel was confirmed by ASTM D-6751, H and C-NMR, GC-MS, and FT-IR spectroscopy. The optimum biodiesel yield of 91% was obtained with an oil-to-methanol ratio of 1:24, 15 mg of catalyst concentration, 60 °C temperature, and 45 min of reaction time. Fuel properties were determine
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., Tahereh Hasanloo, Ramzan Ali Khavari-N. ., Eslam Majidi ., and Mohammad Reza Shams . "Analysis of Flavonolignans in Dried Fruits of Silybum marianum (L.) Gaertn from Iran." Pakistan Journal of Biological Sciences 8, no. 12 (2005): 1778–82. http://dx.doi.org/10.3923/pjbs.2005.1778.1782.

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Sharipboyeva, Yulduz Muzafarovna, and Miriban Raimovna Askarova. "Analysis of the root and root circumference nematode of silybum marianum (L) gaertn." ACADEMICIA: An International Multidisciplinary Research Journal 12, no. 5 (2022): 1236–38. http://dx.doi.org/10.5958/2249-7137.2022.00595.x.

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Sardrood, Babak Pakdaman, and Mohammad Farkhari. "Milk Thistle (Silybum marianum (L.) Gaertn.) seed fungi in a sub-tropical district." Journal of Innovative Agriculture 8, no. 1 (2021): 11. http://dx.doi.org/10.37446/jinagri/rsa/8.1.2021.11-15.

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COȘERAN, Mihaela Anca, Emilia CONSTANTINESCU, Andreea ONA, Simona BALAȘ, and Marcel DUDA. "Milk Thistle [Silybum marianum (L.) Gaertn.] - a Very Useful Plant for People's Health." Hop and Medicinal Plants 30, no. 1-2 (2022): 70–83. https://doi.org/10.15835/hpm.v30i1-2.14439.

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Milk thistle, a species mentioned from the time of Greek philosophers, is well known due to one of its constituents, silymarin, and used in the treatment of several liver disorders. Even though the majority of the documentary data on Silybum marianum focuses on its role in liver diseases, more information has recently become available regarding the herb's beneficial effects on a variety of other diseases, including protection for the kidneys, hypolipidemic and anti-atherosclerotic activities, cardiovascular protection, prevention of insulin resistance, particularly in cirrhotic patients, cance
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COȘERAN, Mihaela Anca, Emilia CONSTANTINESCU, Andreea ONA, Simona BALAȘ, and Marcel DUDA. "Milk Thistle [Silybum marianum (L.) Gaertn.] - a Very Useful Plant for People's Health." Hop and Medicinal Plants 30, no. 1-2 (2022): 70–83. https://doi.org/10.15835/hamp14439.

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Milk thistle, a species mentioned from the time of Greek philosophers, is well known due to one of its constituents, silymarin, and used in the treatment of several liver disorders. Even though the majority of the documentary data on Silybum marianum focuses on its role in liver diseases, more information has recently become available regarding the herb's beneficial effects on a variety of other diseases, including protection for the kidneys, hypolipidemic and anti-atherosclerotic activities, cardiovascular protection, prevention of insulin resistance, particularly in cirrhotic patients, cance
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Eskandari Nasrabadi, Samieh, Reza Ghorbani, Parviz Rezvani Moghaddam, and Mehdi Nassiri Mahallati. "Phenological response of milk thistle (Silybum marianum [L.] Gaertn.) to different nutrition systems." Journal of Applied Research on Medicinal and Aromatic Plants 1, no. 4 (2014): 148–51. http://dx.doi.org/10.1016/j.jarmap.2014.10.002.

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Koláčková, Pavla, Gabriela Růžičková, Ivana Šafránková, Karel Hron, and Klára Hrůzová. "Evaluation of the Growth Dynamics and Morphological Characteristics of Genetic Sources of Silybum marianum (L.) Gaertn." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 63, no. 4 (2015): 1141–46. http://dx.doi.org/10.11118/actaun201563041141.

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The aim of this work was to evaluate the growth dynamics and selected morphological characteristics of genetic sources of milk thistle (Silybum marianum L. Gaertn.) for the further development of the minimal set of descriptors. Milk thistle is grown in the Czech Republic for its achenes; however, the quality of achenes can be reduced by many factors, by the occurrence of fungal pathogens mainly. The growth dynamics and morphological characteristics of milk thistle during the vegetation period in the years 2010–2013 at two localities were evaluated. The cluster analysis of the data showed the s
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Janocha, Alina, Anna Milczarek, and Daria Pietrusiak. "Impact of Milk Thistle (Silybum marianum [L.] Gaertn.) Seeds in Broiler Chicken Diets on Rearing Results, Carcass Composition, and Meat Quality." Animals 11, no. 6 (2021): 1550. http://dx.doi.org/10.3390/ani11061550.

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The studies aimed to evaluate the impact of milk thistle seeds in broiler chicken feed rations on rearing results, carcass composition and meat quality. The experiment involved 120 broiler chickens randomly allocated to three equinumerous groups (C, MT02, MT23). Each group was divided into five subgroups of eight chickens each. Over the first 21 days of life the birds were fed starter rations, and over the following 21 days received grower rations. Chicken starter/grower diets in groups MT02 and MT23 were supplemented with ground seeds of milk thistle in the amount of 0/2% (MT02) and 2/3% (MT2
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AKBEL, Erten, and Mustafa KARA. "Optimization of Silymarin Extraction Condition from Silybum marianum (L.) Gaertn and Development of HPLC Method for Its Quantification." ISPEC Journal of Agricultural Sciences 8, no. 1 (2024): 206–20. https://doi.org/10.5281/zenodo.10844360.

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Silybum marianum (milk thistle) and its derivatives are used in the treatment of many diseases, especially liver diseases. In this study, extraction variables required for the industrial process of <em>Silybum marianum</em> (L.) Gaertner, and conditions for silymarin extraction were optimized using RSM (Response surface methodology). For this purpose, the fixed oil content was determined to be approximately 27% in the extraction using hexane in a Soxhlet apparatus with fruits of certain particle size. An HPLC technique was devised and approved to determine the amount of silymarin in the extrac
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Berner, D. K., L. K. Paxson, W. L. Bruckart, D. G. Luster, M. McMahon, and J. L. Michael. "First Report of Silybum marianum as a Host of Puccinia punctiformis." Plant Disease 86, no. 11 (2002): 1271. http://dx.doi.org/10.1094/pdis.2002.86.11.1271b.

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Silybum marianum (L.) Gaertn. (milk thistle) is a problematic invasive weed in the western United States. The rust fungus, Puccinia punctiformis (F. Strauss) Rohl., is found throughout the world as a pathogen of Cirsium arvense (L.) Scop. (Canadian thistle). Recently, plants of S. marianum grown from surface-disinfested seeds in our quarantine greenhouse were parasitized by a rust. Apparently, an isolate of P. punctiformis collected from C. arvense in Turkey that was present in the greenhouse had spread to adjacent S. marianum plants and caused infection without applying any artificial dew per
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Lieshchova, M. A., and V. V. Brygadyrenko. "Effect of Echinacea purpurea and Silybum marianum seeds on the body of rats with an excessive fat diet." Biosystems Diversity 31, no. 1 (2023): 90–99. http://dx.doi.org/10.15421/012310.

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The impact of excess fat and high-calorie intake on the human body is an acute problem for many economically developed countries. Modelling the effects on the health of rats of supplementing their diet with crushed seeds of Echinacea purpurea (L.) Moench and Sylibum marianum (L.) Gaertn was carried out in a laboratory experiment. In the control group of animals, body weight increased by 700 mg/day, with the addition of E. purpurea seeds – by 1394 mg/day and with the addition of S. marianum seeds – by only 155 mg/day. A hypercaloric diet supplemented with E. purpurea caused a significant decrea
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ALEMARDAN, Ali, Anestis KARKANIS, and Reza SALEHI. "Breeding Objectives and Selection Criteria for Milk Thistle [Silybum marianum (L.) Gaertn.] Improvement." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 41, no. 2 (2013): 340. http://dx.doi.org/10.15835/nbha4129298.

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Milk thistle [Silybum marianum (L.) Gaertn.] is an important medicinal-industrial plant. The medicinal compounds of milk thistle are derived from its seeds. The plant is commercially cultivated for the production of silymarin. Cultivation offers the opportunity to optimise achene yield and silymarin content. Furthermore, efforts should be made to develop new cultivars. The main objective of milk thistle breeding is to develop high yielding cultivars with elevated silymarin content. There are few developed cultivars of milk thistle (e.g. Argintiu, Budakalaszi, Szibilla, Khoreslo, Babak Castle,
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Tavakoli, Saeed, Farahnaz Khalighi-Sigaroodi, Reza Hagiaghaee, Mahdi Yaghoobi, and Reza Ghafarzadegan. "Purification, identification, and standardization of silybin A & B composition from Silybum marianum (L.) Gaertn." Journal of Medicinal Plants 21, no. 81 (2022): 1–11. http://dx.doi.org/10.52547/jmp.21.81.1.

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Qayumov Feruz Sobir o'g'li and Tuxtayev Farhod Hakimovich. "Mineral analysis of dry extracts from the seeds of the plant Silybum marianum (L. Gaertner) introduced in Uzbekistan." International Journal on Integrated Education 3, no. 8 (2020): 235–37. http://dx.doi.org/10.31149/ijie.v3i8.573.

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Silybum marianum (L.) Gaerth. (Asteraceae) is a valuable medicinal plant In the domestic and foreign literature the following pharmacological properties of the medicinal forms from Silybum marianum are described: antioxidant, antitoxic, hemostatic, hepatoprotective, detoxification, choleretic, anti-inflammatory, wound healing, reparative, laxatives, tonic, improving digestion, cholekinetic, cholesecret [1,2]. In Uzbekistan, the development of products for functional and therapeutic-preventive purposes for preventing various diseases and strengthening protective functions body, reducing the ris
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Diukendjieva, Antonia, Maya M. Zaharieva, Mattia Mori, et al. "Dual SMO/BRAF Inhibition by Flavonolignans from Silybum marianum." Antioxidants 9, no. 5 (2020): 384. http://dx.doi.org/10.3390/antiox9050384.

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Silymarin is the standardized extract from the fruits of Silybum marianum (L.) Gaertn., a well-known hepatoprotectant and antioxidant. Recently, bioactive compounds of silymarin, i.e., silybins and their 2,3-dehydro derivatives, have been shown to exert anticancer activities, yet with unclear mechanisms. This study combines in silico and in vitro methods to reveal the potential interactions of optically pure silybins and dehydrosilybins with novel protein targets. The shape and chemical similarity with approved drugs were evaluated in silico, and the potential for interaction with the Hedgehog
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Pickova, Darina, Vladimir Ostry, Jakub Toman, and Frantisek Malir. "Presence of Mycotoxins in Milk Thistle (Silybum marianum) Food Supplements: A Review." Toxins 12, no. 12 (2020): 782. http://dx.doi.org/10.3390/toxins12120782.

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The consumption of herbal-based supplements, which are believed to have beneficial effects on human health with no side effects, has become popular around the world and this trend is still increasing. Silybum marianum (L.) Gaertn, commonly known as milk thistle (MT), is the most commonly studied herb associated with the treatment of liver diseases. The hepatoprotective effects of active substances in silymarin, with silybin being the main compound, have been demonstrated in many studies. However, MT can be affected by toxigenic micro-fungi and contaminated by mycotoxins with adverse effects. T
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Rosińska, Agnieszka, Hanna Dorna, and Dorota Szopińska. "EFFECTS OF OSMOPRIMING ON GERMINATION, VIGOUR AND HEALTH OF SILYBUM MARIANUM (L.) GAERTN. SEEDS." Acta Scientiarum Polonorum Hortorum Cultus 16, no. 3 (2017): 13–25. http://dx.doi.org/10.24326/asphc.2017.3.2.

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Stoiljkovic, Zora, Slobodan Petrovic, and Biljana Ilic. "Examination of localization of silymarin and fatty oil in Silybum marianum (L.) Gaertn. fruit." Chemical Industry and Chemical Engineering Quarterly 13, no. 2 (2007): 55–59. http://dx.doi.org/10.2298/ciceq0702055s.

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Physical characteristics and localization of flavonoids and fatty oil in Silybum marianum (L.) Gaertn. fruit of different origin were examined. Physical characteristics of the fruit were determined by its origin, and samples cultivated on plantations were, concerning their colour, shine, shape and size, very similar to those they originated from. By examination of the fruit size, we wanted to give our contribution to the choice of adequate equipment for picking, cleaning and packing of the fruit. Using a suitable mechanical procedure, the separation of the fruit into its inner part (endosperm)
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