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1

Grosfils, Valérie. "Modelling and parametric estimation of simulated moving bed chromatographic processes (SMB)." Doctoral thesis, Universite Libre de Bruxelles, 2009. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210313.

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La chromatographie à lit mobile simulé (procédé SMB) est une technique de séparation bien maîtrisée dans certains secteurs traditionnels tels que la séparation de sucres et d’hydrocarbures. Cependant, son application à la séparation de composés à haute valeur ajoutée dans l’industrie pharmaceutique pose de nouveaux problèmes liés à la nature des produits à séparer ainsi qu'aux exigences plus strictes en matière de pureté et de quantités produites. Les principaux problèmes ouverts sont notamment la détermination des conditions de fonctionnement optimales, la conception de structures robustes de
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Yao, Hong Mei. "Wavelet based dynamic modelling of simulated moving bed chromatographic processes." Curtin University of Technology, Department of Chemical Engineering, 2009. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=128426.

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Simulated moving bed chromatography process (SMBCP) is the technical realisation of a countercurrent adsorption process through the cyclic port switching. SMB technology reduces the cost of packing material with high loading capacity and provides high purity and high recovery in a very short time. Major commodity applications have been found in the petroleum, food, biotechnology, pharmaceutical and fine chemical industries. The industrial applications bring an emergent demand to improve the SMBCP operation for higher product quality, productivity, efficiency and robustness. However, for this p
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3

Pou, Ibar Josep Oriol. "Prototipus per al disseny ràpid de separadors continus per adsorció o partició." Doctoral thesis, Universitat Ramon Llull, 2009. http://hdl.handle.net/10803/9295.

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S'han creat les eines necessàries per a estudiar la viabilitat de dur a terme la separació de mescles de dos i tres components basats en un mètode de separació en continu tipus SMB. Amb aquesta finalitat, s'ha creat un sistema per al disseny ràpid i econòmic de separadors SMB que permet simular el comportament d'una columna qualsevol integrada en un sistema SMB. Aquest sistema, està constituït per una sola columna cromatogràfica que pot treballar en qualsevol de les quatre zones en què es pot dividir un SMB.<br/><br/>El sistema de control de l'instrument permet simular cicles complets de separ
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Bergeot, Ghislain. "Extension du concept "One-column" au lit mobile simulé réactif : application à la séparation réactive des C8 aromatiques." Thesis, Vandoeuvre-les-Nancy, INPL, 2010. http://www.theses.fr/2010INPL057N/document.

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La séparation des C8 aromatiques par Lit Mobile Simulé (LMS) permet d'obtenir du paraxylène (PX) pur. Les autres composés du mélange sont recyclés dans un réacteur afin d'être isomérisés puis séparés à nouveau. La charge du LMS est composée à environ 75% par ce flux de recyclage. L'intégration de la réaction dans le LMS, réalisée en intercalant des réacteurs d'isomérisation entre les lits d'adsorbant de la zone 3 (procédé LMS Réactif, LMSR), doit permettre une réduction de ce flux de recyclage.L'objectif de cette thèse est de développer une méthodologie d'étude des procédés de type Lit Mobile
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5

Kessler, Lars Christian. "Enhancing the potential of simulated moving bed chromatography." Magdeburg Docupoint-Verl, 2009. http://d-nb.info/994522819/04.

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6

Aniceto, José Pedro Salgado Castro. "Separation of triterpenic acids by simulated moving bed chromatography." Doctoral thesis, Universidade de Aveiro, 2018. http://hdl.handle.net/10773/22882.

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Doutoramento em Engenharia Química<br>A exploração de compostos, subprodutos e resíduos naturais é um passo chave para a obtenção de um futuro sustentável. A valorização e comercialização destes materiais dependem da aplicação de técnicas adequadas de conversão e separação/purificação que permitam obter os níveis desejados de pureza e produtividade. Os ácidos triterpénicos, particularmente os ácidos betulínico, oleanólico e ursólico, são compostos de elevado valor que têm atraído interesse devido às suas já reportadas propriedades nutraceuticas e farmacológicas. Estes triterpenoides es
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Bechtold, Matthias. "Integrated operation of enzymatic racemisation and chiral simulated moving bed technology /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17111.

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8

Toumi, Abdelaziz [Verfasser]. "Optimaler Betrieb und Regelung von Simulated-Moving-Bed-Prozessen / Abdelaziz Toumi." Aachen : Shaker, 2005. http://d-nb.info/1181621585/34.

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9

Pilgrim, Axel. "A Novel Biochemical Process using the Simulated Moving-Bed Chromatographic Reactor." 京都大学 (Kyoto University), 2002. http://hdl.handle.net/2433/149826.

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10

Suvarov, Paul [Verfasser], and Achim [Akademischer Betreuer] Kienle. "Robuste Regelung von Simulated Moving Bed Chromatographieprozessen / Paul Suvarov ; Betreuer: Achim Kienle." Magdeburg : Universitätsbibliothek, 2016. http://d-nb.info/1115795317/34.

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11

Bentley, Jason A. "Systematic process development by simultaneous modeling and optimization of simulated moving bed chromatography." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/47531.

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Adsorption separation processes are extremely important to the chemical industry, especially in the manufacturing of food, pharmaceutical, and fine chemical products. This work addresses three main topics: first, systematic decision-making between rival gas phase adsorption processes for the same separation problem; second, process development for liquid phase simulated moving bed chromatography (SMB); third, accelerated startup for SMB units. All of the work in this thesis uses model-based optimization to answer complicated questions about process selection, process development, and control o
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Zahn, Volker Michael [Verfasser]. "Adiabatic Simulated Moving Bed Reactor : Principle, Nonlinear Analysis and Experimental Demonstration / Volker Michael Zahn." Aachen : Shaker, 2012. http://d-nb.info/1052408672/34.

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13

Küpper, Achim [Verfasser]. "Optimization, State Estimation, and Model Predictive Control of Simulated Moving Bed Processes / Achim Küpper." Aachen : Shaker, 2010. http://d-nb.info/1101185333/34.

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Yu, Yueying. "Simulation and Comparison of Operational Modes in Simulated Moving Bed Chromatography and Gas-Phase Adsorptive Separation." Diss., Virginia Tech, 2016. http://hdl.handle.net/10919/78319.

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This dissertation describes the simulation and optimization of adsorptive and chromatographic separation processes. The first part focus on the simulation and comparison of operational modes in simulated moving bed (SMB) chromatography for separation and purification in bioprocesses. The second part includes the simulation of gas-phase adsorptive processes by pressure swing adsorption and temperature swing adsorption technologies. The applications of SMB chromatography are popular in separating and purifying enantiomers, petrochemicals, pharmaceuticals and biochemicals with higher yield and l
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Wood, Kevin. "Development of Computational Tools for the Design, Simulation and Optimization of Cyclic Steady State (CSS) Adsorption and Chromatographic Processes." Diss., Virginia Tech, 2016. http://hdl.handle.net/10919/72854.

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This dissertation presents an analysis of two aspects of the chromatographic separation process known as Simulated Moving Bed (SMB) chromatography. The first aspect is system design, and the second is improving computer simulations to generate heuristics for choosing operational modes. For the past 15-20 years, there has been a surge of interest in the use of Simulated Moving Bed systems for the chromatographic separation of chemicals¹. A wide variety of methods, nomenclatures, and conventions have been adopted over the years²⁻⁴, as teams from different backgrounds adopt and improve on the
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Li, Suzhou [Verfasser], and Jörg [Akademischer Betreuer] Raisch. "Optimal steady state and transient operation of simulated moving bed chromatographic processes / Suzhou Li. Betreuer: Jörg Raisch." Berlin : Universitätsbibliothek der Technischen Universität Berlin, 2012. http://d-nb.info/1019853131/34.

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Agrawal, Gaurav. "Systematic optimization and experimental validation of simulated moving bed chromatography systems for ternary separations and equilibrium limited reactions." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/54028.

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Simulated Moving Bed (SMB) chromatography is a separation process where the components are separated due to their varying affinity towards the stationary phase. Over the past decade, many modifications have been proposed in SMB chromatography in order to effectively separate a binary mixture. However, the separation of multi-component mixtures using SMB is still one of the major challenges. Although many different strategies have been proposed, previous studies have rarely performed comprehensive investigations for finding the best ternary separation strategy from various possible alternatives
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18

Silva, Francisco Vitor Santos da [Verfasser]. "Analysis and design of center-cut separations using 8-zone simulated moving bed chromatography / Francisco Vitor Santos da Silva." Magdeburg : Universitätsbibliothek, 2017. http://d-nb.info/1145017614/34.

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19

Martínez, Cristancho Carlos Andrés [Verfasser]. "Process for continuous purification of single-chain antibody fragments based on Simulated Moving Bed Chromatography / Carlos Andrés Martínez Cristancho." Aachen : Shaker, 2013. http://d-nb.info/1049383737/34.

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Kanchanalai, Pakkapol. "New dehydration and pretreatment process for ethanol production from biomass." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/53559.

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The cost of pretreatment process for saccharification from biomass and the cost of dilute ethanol purification are significant components of the overall cost for fuel grade ethanol production through fermentation or other biological routes. This work focuses on developing optimal designs of dilute ethanol purification process and the new acid hydrolysis technology for the production of fermentable sugars from biomass where the overarching goal is to reduce the cost of ethanol production from biomass. In this thesis, the ethanol separation process with the reverse osmosis membrane pretreatment
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21

Lemoine, Nava Jose Roberto [Verfasser]. "Online optimal design of experiments and parametrization of chemical processes: Application to the Simulated Moving Bed Process / Jose Roberto Lemoine Nava." Aachen : Shaker, 2018. http://d-nb.info/1188550543/34.

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22

Fangueiro, Gomes Leonel. "Etude du couplage hydrodynamique/adsorption : application au lit mobile simulé." Thesis, Ecully, Ecole centrale de Lyon, 2015. http://www.theses.fr/2015ECDL0031.

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Modèle monodimensionnel de type Piston-Dispersion. Le terme de dispersion axiale englobe alors toutes les imperfections de l'écoulement : injection des fluides non homogène dans l’espace et étalée dans le temps, effet de parois, et enfin volumes morts derrière les obstacles noyés dans le tamis (poutres, conduites...) dans le cas des Lits Mobiles Simulés. Cette représentation, quoique très simpliste, s'avère généralement suffisante tant que l’étalement des fronts de concentration est d'abord induit par les limitations au transfert externe, interne (macro/microporeux) et par la thermodynamique d
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23

Dias, Raquel Macedo. "Separação cromatografica quiral do o,p'-diclorodifenildicloroetano (mitotano) em fase estacionaria quiral O,O'bis[4-terc-butilbenzoil]-N,N'dialil-L-tartadiamida." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266169.

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Orientador: Cesar Costapinto Santana<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica<br>Made available in DSpace on 2018-08-08T16:18:50Z (GMT). No. of bitstreams: 1 Dias_RaquelMacedo_M.pdf: 1158217 bytes, checksum: 17fc0268f6869b95e17b301e65d69e9c (MD5) Previous issue date: 2007<br>Resumo: O mitotano (o,p?-diclorodifenildicloroetano) é um fármaco utilizado no tratamento de carcinoma adrenocortical. Ele é comercializado na forma racêmica, ou seja, na proporção 1:1 dos seus enantiômeros R e S. A influência da quiralidade da molécula sobre seu efei
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24

Morey, Céline. "Optimisation des procédés chromatographiques multicolonnes continus : développement d'un système de contrôle avancé." Thesis, Vandoeuvre-les-Nancy, INPL, 2009. http://www.theses.fr/2009INPL003N.

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Les procédés chromatographiques multicolonnes continus se sont imposés comme technique séparative dans l’industrie pharmaceutique en raison de leur productivité élevée et de leur développement rapide. De nos jours, la modélisation, le dimensionnement et l’optimisation des procédés LMS et Varicol sont considérés comme établis. Le fonctionnement automatique optimisé et robuste de ces procédés reste cependant un sujet de recherche. Le plus souvent, les paramètres opératoires sont choisis en deçà du réglage optimal afin d’inclure une marge de robustesse. Ils sont ajustés manuellement par un opérat
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25

Bihain, Anderson Luis Jeske. "Desenvolvimento e avaliação de novas abordagens de modelagem de processos de separação em leito móvel simulado." Universidade do Estado do Rio de Janeiro, 2014. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=6458.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>O Leito Móvel Simulado (LMS) é um processo de separação de compostos por adsorção muito eficiente, por trabalhar em um regime contínuo e também possuir fluxo contracorrente da fase sólida. Dentre as diversas aplicações, este processo tem se destacado na resolução de petroquímicos e principalmente na atualidade na separação de misturas racêmicas que são separações de um grau elevado de dificuldade. Neste trabalho foram propostas duas novas abordagens na modelagem do LMS, a abordagem Stepwise e a abordagem Front Velocity. Na modelage
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Veredas, Vinícius de. "Cromatografia continua em leito movel simulado para a purificação dos enantiomeros do N-Boc-baclofeno-lactama." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/332008.

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Orientador: Cesar Costapinto Santana<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica<br>Made available in DSpace on 2018-08-30T12:54:54Z (GMT). No. of bitstreams: 1 Veredas, Vinicius de_D.pdf: 13205142 bytes, checksum: 97c5009c255088bef6fcdc1fd92294c3 (MD5) Previous issue date: 2005<br>Doutorado<br>Desenvolvimento de Processos Biotecnologicos<br>Mestre em Engenharia Química
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Romualdo, Kamilla Vogas. "Problemas direto e inverso de processos de separação em leito móvel simulado mediante mecanismos cinéticos de adsorção." Universidade do Estado do Rio de Janeiro, 2012. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=6750.

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Diversas aplicações industriais relevantes envolvem os processos de adsorção, citando como exemplos a purificação de produtos, separação de substâncias, controle de poluição e umidade entre outros. O interesse crescente pelos processos de purificação de biomoléculas deve-se principalmente ao desenvolvimento da biotecnologia e à demanda das indústrias farmacêutica e química por produtos com alto grau de pureza. O leito móvel simulado (LMS) é um processo cromatográfico contínuo que tem sido aplicado para simular o movimento do leito de adsorvente, de forma contracorrente ao movimento do líquido,
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Arafah, Rami. "Separation of nadolol stereoisomers by liquid chromatography using Chiralpak IA chiral stationary phase." Master's thesis, 2015. http://hdl.handle.net/10198/12816.

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The main objective of this work is to study the chiral separation of stereoisomers of nadolol by preparative liquid chromatography. In this report it is presented the state of the art and experimental results obtained for optimizing the methodology for preparative scale separation of nadolol stereoisomers using an immobilized chiral stationary phase (Chiralpak® IA). The screening of the solvent composition is based on the best solvent or solvents mixture to perform the pseudo-binary separation (1+2+3/4) of the more retained stereoisomer using the simulated moving bed technology. The three lea
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Pais, Luís Manuel Santos. "Chiral separation by simulated moving bed chromatography." Tese, 1999. http://hdl.handle.net/10216/11373.

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Silva, Viviana Manuela Tenedório Matos da. "Diethylacetal synthesis in simulated moving bed reactor." Tese, 2003. http://hdl.handle.net/10216/11040.

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Pais, Luís S. "Chiral separation by simulated moving bed chromatography." Doctoral thesis, 1999. http://hdl.handle.net/10198/1145.

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The general objective of this work is the study of the behaviour of the Simulated Moving Bed (SMB) processes, with applications to chiral separations. Briefly, SMB chromatography allows the continuous injection and separation of binary mixtures. The simulated countercurrent contact between the solid and liquid phases maximizes the mass transfer driving force, leading lo a significant reduction in mobile and stationary phases consumption when cornpared with elution chromatography. The problem of modeling a SMB separation process is analyzed by two different strategies: one, by simulating the s
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Pais, Luís Manuel Santos. "Chiral separation by simulated moving bed chromatography." Doctoral thesis, 1999. http://hdl.handle.net/10216/11373.

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Silva, Viviana Manuela Tenedório Matos da. "Diethylacetal synthesis in simulated moving bed reactor." Doctoral thesis, 2003. http://hdl.handle.net/10216/11040.

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34

Liang, Ru-Chien, and 梁茹茜. "The Integration of Simulated Moving Bed and Supercritical Fluid and Its Application and the Ternary Separation by Simulated Moving Bed." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/82658d.

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博士<br>義守大學<br>化學工程學系暨生物技術與化學工程研究所<br>107<br>Separation and purification is the basic technology for industry. It works for the pretreatment of raw materials and the purification of final products for petrochemicals, specialities, biotechnologies, pharmaceuticals. Compared to distillation and membrane separation, chromatography is more widely apply in biotechnology and pharmaceutical industries because of low-temperature operation and high selectivity of adsorbent. SMB(Simulated Moving Bed), one of the continuous chromatographic technique, can greatly increase the productivity of solid adsorben
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Ribeiro, Diogo Rafael Pacheco. "Bioactive compounds separation with simulated moving bed technology." Master's thesis, 2019. http://hdl.handle.net/10773/30277.

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The pharmaceutical industry is developing a growing interest in natural compounds with biological and nutritional properties. Betulinic and oleanolic acids are two naturally occurring triterpenic acids, which possess such characteristics. These two compounds can be extracted from natural resources, i.e., from the bark of Eucalyptus globulus. However, their separation is difficult because these compounds present similar structures (they are constitutional isomers). In this work, the chromatographic separation of betulinic and oleanolic acids from representative extracts of E. globulus was stud
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Santos, Cristiana Areia dos. "Bioactive compounds separation with simulated moving bed technology." Master's thesis, 2018. http://hdl.handle.net/10773/25696.

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Natural products have been progressively forgotten by major pharmaceutical research companies as sources for new drugs in the last half century. Currently one observes a change of strategy, which is promoting a renewed interest on the integration of natural products into pharmaceuticals. Triterpenic acids are a promising group of plant secondary metabolites occurring in cuticular waxes covering fruits, owers, and leaves, providing a wide variety of bene cial biological activities. In this dissertation it was studied the oleanolic and ursolic acids isolation by chromatographic tecnique
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Liang, Ru-Chien, and 梁茹茜. "Separation of sesamin and sesamolin by Simulated Moving Bed." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/80900639882801839332.

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碩士<br>義守大學<br>生物技術與化學工程研究所碩士班<br>98<br>SMB (simulated moving bed) is a continuous chromatographic separation technology. Compared with batch-type preparative chromatography, the advantages of SMB include high yield, high purity, and high efficiency per unit weight of the adsorbent. In addition, SMB can be readily scaled-up for higher volume purification and can be conducted relatively quickly to meet the demand of tightened schedule in new product development. This work report the separations of sesamin and sesamolin, respectively, by two SMBs. The two SMBs have different piping design and con
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Minceva, Mirjana. "Separation/isomerization of xylenes by simulated moving bed technology." Tese, 2004. http://hdl.handle.net/10216/13926.

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Minceva, Mirjana. "Separation/isomerization of xylenes by simulated moving bed technology." Doctoral thesis, 2004. http://hdl.handle.net/10216/13926.

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Ping, Li. "Proteins separation and purification by expanded bed chromatography and simulated moving bed technology." Tese, 2006. http://hdl.handle.net/10216/12438.

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Ping, Li. "Proteins separation and purification by expanded bed chromatography and simulated moving bed technology." Doctoral thesis, 2006. http://hdl.handle.net/10216/12438.

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Dias, Rafael Osório Marques. "Gas-phase simulated moving bed for methane and nitrogen separation." Master's thesis, 2019. https://hdl.handle.net/10216/121953.

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Fütterer, Marco [Verfasser]. "On design and control of simulated moving bed plants / von Marco Fütterer." 2010. http://d-nb.info/1005342768/34.

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LOH, RONG-REN, and 羅榮仁. "Experimental Study of Continuous Separation of Enantiomers by Simulated Moving Bed Chromatography." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/59920715334831911246.

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碩士<br>國立雲林科技大學<br>工業化學與災害防治研究所碩士班<br>89<br>The simulated moving-bed (SMB) technology developed by UOP has been used in chemical industry for several bulk large-scale separations known as SORBEX processes. This technology has been recently applied in new areas such as biotechnology, pharmaceutical, and fine chemistry. Especially in the pharmaceutical industry, SMB is considered to be the best technology for continuous large-scale production of enantiomers. The concept of the SMB is base on the true moving bed (TMB) process, where the liquid goes up and solid goes down in each zone, and then the
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Faria, Rui Pedro Vieira. "Glycerol valorisation as biofuel: Glycerol acetals production by Simulated Moving Bed Reactor." Tese, 2013. https://repositorio-aberto.up.pt/handle/10216/82655.

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LIN, CHIA-HUA, and 林佳樺. "Design of the simulated moving bed process to separate HMF and DMAC." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/4eyt99.

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碩士<br>國立臺北科技大學<br>化學工程與生物科技系化學工程碩士班<br>107<br>The objective of this study is to purify hydroxymethylfurfural (HMF) from dime-thylacetamide (DMAC) by designing a simulated moving bed (SMB) process. HMF is a heat-sensitive compound therefore is suitable for purification by liquid chromatography. After obtaining the isotherm parameters of the two materials from the pulse and frontal ex-periments. Aspen, a process design software, was used to find the optimized separation process. In order to evaluate the effects of mass transfer on SMB, two adsorbents, C18 and polystyrene, were chose to study. Th
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Ribeiro, Rita Fonseca e. Silva Tavares. "8-zone Simulated Moving Bed Chromatography for the separation of ternary mixtures." Master's thesis, 2016. http://hdl.handle.net/10362/19988.

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Simulated Moving Bed Chromatography is a well-established separation method. Its conventional system has proved its utility for the separation of binary mixtures. Since in industry one of the main challenges is to separate complex mixtures, several studies were conducted and novel structures have been proposed to address this problem, including the 8-zone Simulated Moving Bed. This works’ aim is to experimentally demonstrate the isolation of an intermediary eluting molecule out of a pseudo ternary mixture using 8-zone SMB. This was performed through adsorption isotherm characterization, using
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Araújo, João Miguel Mendes de. "Optimal design and operation of compact simulated moving bed processes for enantioseparations." Doctoral thesis, 2009. http://hdl.handle.net/10362/15752.

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Simulated moving bed (SMB) chromatography is attracting more and more attention since it is a powerful technique for complex separation tasks. Nowadays, more than 60% of preparative SMB units are installed in the pharmaceutical and in the food in- dustry [SDI, Preparative and Process Liquid Chromatography: The Future of Process Separations, International Strategic Directions, Los Angeles, USA, 2002. http://www. strategicdirections.com]. Chromatography is the method of choice in these ¯elds, be- cause often pharmaceuticals and ¯ne-chemicals have physico-chemical properties which di®er li
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Chibério, Abimaelle Silva. "Single-Column Chromatography with Recycle Lag Analog to Simulated Moving Bed Processes." Doctoral thesis, 2019. http://hdl.handle.net/10362/90890.

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Abstract:
The chromatography steps dominate the Downstream Processing (DSP) costs of a new biopharmaceutical, which has propelled the biopharmaceutical industry to invest a lot of effort on their improvement in order to reduce the costs of the biopharmaceutical production. Liquid chromatography (LC) is currently the core technique within the DSP strategy for the purification of biopharmaceuticals. Although single-column batch chromatography is simpler to operate than continuous (multicolumn) chromatography, the latter has many advantages over the former, including improved purity, yield, and prod
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50

Antunes, João Cabaço. "Programming and Control of a Single-Column Analog Simulated Moving Bed Process." Master's thesis, 2018. http://hdl.handle.net/10362/52847.

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Abstract:
With the advancements in technology, the development of tools for the control and testing of the progress in different fields, such as chromatography, has become essential in concerns to lab work and prototyping. As such, many programming languages have been adapted and developed with the objective to make the development of such tools easier. As our group built the Single-Column Analog Simulated Moving Bed chromatography process, the need for a versatile program to ease and simplify the procedure of tests and adjustments was met with the development of a tool written in the Julia and Python
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