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Journal articles on the topic 'Sinapic acid'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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1

Le, Tuong Thi, Xavier Framboisier, Arnaud Aymes, Armelle Ropars, Jean-Pol Frippiat, and Romain Kapel. "Identification and Capture of Phenolic Compounds from a Rapeseed Meal Protein Isolate Production Process By-Product by Macroporous Resin and Valorization Their Antioxidant Properties." Molecules 26, no. 19 (2021): 5853. http://dx.doi.org/10.3390/molecules26195853.

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In this study, phenolic compounds from an aqueous protein by-product from rapeseed meal (RSM) were identified by HPLC-DAD and HPLC-ESI-MS, including sinapine, sinapic acid, sinapoyl glucose, and 1,2-di-sinapoyl gentibiose. The main phenolic compound in this by-product was sinapine. We also performed acid hydrolysis to convert sinapine, and sinapic acid derivatives present in the permeate, to sinapic acid. The adsorption of phenolic compounds was investigated using five macroporous resins, including XAD4, XAD7, XAD16, XAD1180, and HP20. Among them, XAD16 showed the highest total phenolic conten
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Garbiec, Ewa, Natalia Rosiak, Ewa Tykarska, Przemysław Zalewski, and Judyta Cielecka-Piontek. "Sinapic Acid Co-Amorphous Systems with Amino Acids for Improved Solubility and Antioxidant Activity." International Journal of Molecular Sciences 24, no. 6 (2023): 5533. http://dx.doi.org/10.3390/ijms24065533.

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The objective of this study was to obtain co-amorphous systems of poorly soluble sinapic acid using amino acids as co-formers. In order to assess the probability of the interaction of amino acids, namely, arginine, histidine, lysine, tryptophan, and proline, selected as co-formers in the amorphization of sinapic acid, in silico studies were carried out. Sinapic acid systems with amino acids in a molar ratio of 1:1 and 1:2 were obtained using ball milling, solvent evaporation, and freeze drying techniques. X-ray powder diffraction results confirmed the loss of crystallinity of sinapic acid and
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3

Yu, Myeongnam, Hyun Joo Kim, Huijin Heo, et al. "Comparison of the Antihypertensive Activity of Phenolic Acids." Molecules 27, no. 19 (2022): 6185. http://dx.doi.org/10.3390/molecules27196185.

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Phenolic acids, found in cereals, legumes, vegetables, and fruits, have various biological functions. We aimed to compare the antihypertensive potential of different phenolic acids by evaluating their ACE inhibitory activity and cytoprotective capacity in EA.hy 926 endothelial cells. In addition, we explored the mechanism underlying the antihypertensive activity of sinapic acid. Of all the phenolic acids studied, sinapic acid, caffeic acid, coumaric acid, and ferulic acid significantly inhibited ACE activity. Moreover, gallic acid, sinapic acid, and ferulic acid significantly enhanced intracel
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4

Chadni, Morad, Amandine L. Flourat, Valentin Reungoat, Louis M. M. Mouterde, Florent Allais, and Irina Ioannou. "Selective Extraction of Sinapic Acid Derivatives from Mustard Seed Meal by Acting on pH: Toward a High Antioxidant Activity Rich Extract." Molecules 26, no. 1 (2021): 212. http://dx.doi.org/10.3390/molecules26010212.

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The aim of this paper is to study the effect of the pH on the extraction of sinapic acid and its derivatives from mustard seed meal. Solutions of acidic pH (pH 2), basic pH (pH 12) and distilled water (uncontrolled pH ~ 4.5) were tested at different percentages of ethanol. The maximum extraction yield for sinapic acid (13.22 µmol/g of dry matter (DM)) was obtained with a buffered aqueous solution at pH 12. For ethyl sinapate, the maximum extraction yield reached 9.81 µmol/g DM with 70% ethanol/buffered aqueous solution at pH 12. The maximum extraction yield of sinapine (15.73 µmol/g DM) was ac
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5

Bae, In-Seon, and Sang Hoon Kim. "Sinapic Acid Promotes Browning of 3T3-L1 Adipocytes via p38 MAPK/CREB Pathway." BioMed Research International 2020 (April 9, 2020): 1–8. http://dx.doi.org/10.1155/2020/5753623.

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Sinapic acid is a plant-derived phenolic compound, which acts as an antioxidant, anticancer, and anti-inflammatory agent. Although sinapic acid is valuable in a variety of therapeutic applications, its role in the improvement of obesity-related metabolic disease is relatively unexplored. Brown-like adipocytes (beige adipocytes) are characterized by a high concentration of mitochondria and high expression of uncoupling protein 1 (UCP1), which has specific functions in energy expenditure and thermogenesis. This study assessed the browning effects of sinapic acid in 3T3-L1 adipocytes. We investig
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6

R, Nithya, and Subramanian S. "ANTIOXIDANT PROPERTIES OF SINAPIC ACID: IN VITRO AND IN VIVO APPROACH." Asian Journal of Pharmaceutical and Clinical Research 10, no. 6 (2017): 255. http://dx.doi.org/10.22159/ajpcr.2017.v10i6.18263.

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Objective: This study was aimed to evaluate the antioxidant potential of sinapic acid in both in vitro and in vivo. Recently, we have reported that oral administration of sinapic acid (3,5-dimethoxy 4-hydroxycinnamic acid) an active phyto ingredient widely distributed in rye, mustard, berries, and vegetables has been shown to ameliorate hyperglycemia.Methods: Experimental Type 2 diabetes was induced in male Wistar rats by feeding high-fat diet to induce insulin resistance followed by intraperitoneal administration of a single low dose streptozotocin (35 mg/kg body weight [bw]). Sinapic acid wa
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7

Russo, Stefano, Giuliana Greco, and Maria Grazia Sarpietro. "Assessment of Pharmaco-Technological Parameters of Solid Lipid Nanoparticles as Carriers for Sinapic Acid." Micro 3, no. 2 (2023): 510–20. http://dx.doi.org/10.3390/micro3020034.

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Sinapic acid, 3,5-dimethoxyl-4-hydroxycinnamic acid, belonging to the class of hydroxycinnamic acids, shows antioxidant, anti-inflammatory, anticancer, hepatoprotective, cardioprotective, renoprotective, neuroprotective, antidiabetic, anxiolytic, and antibacterial activity. The aim of this work was to incorporate sinapic acid into solid lipid nanoparticles in order to improve its bioavailability. SLNs were prepared using the hot high-speed homogenization method. The pharmaco-technological properties and thermotropic profile of SLNs encapsulated with sinapic acid, as well as their interaction w
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8

Giresha, Aladahalli S., Deepadarshan Urs, Sophiya Pundalik, et al. "Sinapicacid Inhibits Group IIA Secretory Phospholipase A2 and Its Inflammatory Response in Mice." Antioxidants 11, no. 7 (2022): 1251. http://dx.doi.org/10.3390/antiox11071251.

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Human Group IIA secreted phospholipase A2 (sPLA2-IIA) enzyme plays a crucial role in several chronic inflammatory diseases such asasthma, atherosclerosis, gout, bronchitis, etc. Several studies showed that the antioxidants exert an anti-inflammatory function by inhibiting the sPLA2-IIA enzyme. Hence, the present study evaluated an antioxidant molecule, sinapic acid, for sPLA2-IIA inhibition as an anti-inflammatory function. Initially, the antioxidant efficacy of sinapic acid was evaluated, and it showed greater antioxidant potency. Further, sinapic acid inhibited 94.4 ± 4.83% of sPLA2-IIA acti
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9

Dai, Xi Chun, Zhi Wei Hang, and Xiang Rong Wang. "Studies on the Effect of Sinapic Acid on Silk Fabric Printing with Sorghum Red." Advanced Materials Research 796 (September 2013): 395–99. http://dx.doi.org/10.4028/www.scientific.net/amr.796.395.

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In order to improve fastness of printing silk fabric with natural dyes, the influence of sinapic acid on printing of silk fabric with sorghum red was investigated in this work. The silk fabric was printed using guar gum as paste, sorghum red as natural dye, sinapic acid as auxiliaries. The appropriate steaming condition was the temperature 100°C, time 15min and saturated steam. The results showed that the light fastness and the wash fastness of the printed fabric were improved by the addition of sinapic acid. It is proposed that sinapic acid can be applied as effective fastness improver of nat
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10

Lee, In-Seo, Ga-Young Choi, Inturu Sreelatha, et al. "Effect of Sinapic Acid on Scopolamine-Induced Learning and Memory Impairment in SD Rats." Brain Sciences 13, no. 3 (2023): 427. http://dx.doi.org/10.3390/brainsci13030427.

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The seriousness of the diseases caused by aging have recently gained attention. Alzheimer’s disease (AD), a chronic neurodegenerative disease, accounts for 60–80% of senile dementia cases. Continuous research is being conducted on the cause of Alzheimer’s disease, and it is believed to include complex factors, such as genetic factors, the accumulation of amyloid beta plaques, a tangle of tau protein, oxidative stress, cholinergic dysfunction, neuroinflammation, and cell death. Sinapic acid is a hydroxycinnamic acid found in plant families, such as oranges, grapefruit, cranberry, mustard seeds,
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Li, Mingyue, Xinjie Zhao, Yuxia Sun, Zhen Yang, Guomin Han, and Xue Yang. "Evaluation of Anthocyanin Profile and Color in Sweet Cherry Wine: Effect of Sinapic Acid and Grape Tannins during Aging." Molecules 26, no. 10 (2021): 2923. http://dx.doi.org/10.3390/molecules26102923.

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Cherries are rich in bioactive phenolic compounds and are often fermented into cherry wines. The degradation of anthocyanins during storage will cause color deterioration. The study aimed to utilize sinapic acid and grape tannins in cherry wine to maintain a high fraction in the colored forms of anthocyanins, in order to maximize the color intensity, the latter being associated with good product quality. The effects on the anthocyanin profile and on color parameters of copigments, utilizing spectral measurement combined with UPLC-MS quantitative analysis, have been evaluated in sweet cherry wi
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12

Hussain, Saira, Ata Ur Rehman, Hassan K. Obied, David J. Luckett, and Christopher L. Blanchard. "Extraction, Chemical Characterization, In Vitro Antioxidant, and Antidiabetic Activity of Canola (Brassica napus L.) Meal." Separations 9, no. 2 (2022): 38. http://dx.doi.org/10.3390/separations9020038.

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Canola (Brassica napus L.) meal is a by-product after oil extraction from canola seed and is of relatively low value. This meal may have additional value in the biotechnology, food, and pharmaceutical industries if health-promoting useful bioactive compounds can be identified. Hence, seven canola meal extracts (CMEs) were generated using different organic solvents for two genotypes. HPLC and LCMS analyses were employed for the determination of the phenolic and antioxidant activity of meal extracts, including recovery of major biological compounds. When comparing genotype-1 with genotype-2, the
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13

Zych, Maria, Ilona Kaczmarczyk-Sedlak, Weronika Wojnar, and Joanna Folwarczna. "The Effects of Sinapic Acid on the Development of Metabolic Disorders Induced by Estrogen Deficiency in Rats." Oxidative Medicine and Cellular Longevity 2018 (June 4, 2018): 1–11. http://dx.doi.org/10.1155/2018/9274246.

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Sinapic acid is a natural phenolic acid found in fruits, vegetables, and cereals, exerting numerous pharmacological effects. The aim of the study was to investigate the influence of sinapic acid on biochemical parameters related to glucose and lipid metabolism, as well as markers of antioxidant abilities and parameters of oxidative damage in the blood serum in estrogen-deficient rats. The study was performed on 3-month-old female Wistar rats, divided into 5 groups, including sham-operated control rats, ovariectomized control rats, and ovariectomized rats administered orally with estradiol (0.2
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14

Boulghobra, Doria, Pierre-Edouard Grillet, Mickaël Laguerre, et al. "Sinapine, but not sinapic acid, counteracts mitochondrial oxidative stress in cardiomyocytes." Redox Biology 34 (July 2020): 101554. http://dx.doi.org/10.1016/j.redox.2020.101554.

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15

Xuan, Tran Dang, Do Tuan Bach, and Tran Dang Dat. "Involvement of Phenolics, Flavonoids, and Phenolic Acids in High Yield Characteristics of Rice (Oryza Sativa L.)." International Letters of Natural Sciences 68 (April 2018): 19–26. http://dx.doi.org/10.18052/www.scipress.com/ilns.68.19.

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The present study examined the correlation between phenolic acids and flavonoids with high rice yield traits of rice. It was observed that the difference of phenolic contents among the tested rice lines occurred only in the vegetative stage. The concentrations of phenolic acids were higher in the rice high yield cultivars than low yield variety in the vegetative stage, but they either decreased dramatically or disappeared during the development stage. Caffeic acid was found only in high yield rice, whereas chlorogenic acid was detected only in low yield rice. Sinapic acid was the dominant phen
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Xuan, Tran Dang, Do Tuan Bach, and Tran Dang Dat. "Involvement of Phenolics, Flavonoids, and Phenolic Acids in High Yield Characteristics of Rice (<i>Oryza Sativa</i> L.)." International Letters of Natural Sciences 68 (April 12, 2018): 19–26. http://dx.doi.org/10.56431/p-371651.

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The present study examined the correlation between phenolic acids and flavonoids with high rice yield traits of rice. It was observed that the difference of phenolic contents among the tested rice lines occurred only in the vegetative stage. The concentrations of phenolic acids were higher in the rice high yield cultivars than low yield variety in the vegetative stage, but they either decreased dramatically or disappeared during the development stage. Caffeic acid was found only in high yield rice, whereas chlorogenic acid was detected only in low yield rice. Sinapic acid was the dominant phen
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17

Solanki, Urja B., B. P. Chauhan, Y. M. Shukla, and A. A. Sakure. "Phenol Profiling of Chilli (Capsicum annuum L.) leaves by LC-MS." Journal of Advances in Biology & Biotechnology 27, no. 7 (2024): 1150–58. http://dx.doi.org/10.9734/jabb/2024/v27i71074.

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A lab experiment was conducted at the Department of Biotechnology, Anand Agricultural University, Anand, Gujarat, during 2023. The study focused on phenol profiling of 28 genotypes of chilli along with ACCMS 1 (P1) and ACS 18-08 (P2) using LC-MS. Chilli leaf samples were collected three months after transplanting. A total of 20 phenolic acids were used as standards: salicylic acid, gallic acid, hydroquinone, esculin hydrate, pyrocatechol, methylumbelliferone, umbelliferon, quercetin, coumaric acid, caffeic acid, chlorogenic acid, ferulic acid, cinnamic acid, syringaldehyde, fraxetin, 4-hydroxy
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18

Prabhakar, Preeja, Bakrudeen Ali Ahmed, Saravana Babu Chidambaram, Arun Kumar Ramu, and Arjun Pandian. "Sinapic Acid Improves Neurotransmitter Status and Oxidative Stress-Related Changes in Mouse Model of Experimental Parkinsonism." International Journal of Nutrition, Pharmacology, Neurological Diseases 13, no. 1 (2023): 25–31. http://dx.doi.org/10.4103/ijnpnd.ijnpnd_74_22.

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Parkinsonism is a progressive neurodegenerative disease of the dopaminergic neurons in the substantia nigra. Oxidative stress is a known causative factor in the death of dopaminergic neurons. Sinapic acid (SNP or SA), a hydroxycinnamic type of the abundantly available plant-derived metabolite, is known for its antioxidant and anti-inflammatory properties. In the present study, we assessed the effects of sinapic acid against 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP) induced Parkinson disease (PD) in a mouse model. The animals were pretreated with vehicle or SNP for a period of 5 days.
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19

Nayak, Preeti Sagar, Sunil D. Upadhyaya, and Anubha Upadhyaya. "A HPTLC Densitometer Determination of Sinapic acid in Chandrasur (Lepidium sativum)." Journal of Scientific Research 1, no. 1 (2008): 121–27. http://dx.doi.org/10.3329/jsr.v1i1.1196.

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A qualitative and quantitative analysis method was established to improve quality assessment standards for Lepidium sativum seeds. The sinapic acid was identified by comparing with standards and quantified simultaneously by High performance thin layer chromatographic (HPTLC). HPTLC of Lepidium sativum methanolic extract was performed on Silica gel 60F254 [20 cm × 10 cm] plates with butanol: acetic acid: water (4:1:5), as mobile phase. Quantitative evaluation of the plate was performed in the absorbance-reflectance mode at 326 nm. The sinapic acid was separated on a thin layer of silica gel an
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Bais, Souravh, Renu Kumari, and Yash Prashar. "Ameliorative Effect of Trans-Sinapic Acid and its Protective Role in Cerebral Hypoxia in Aluminium Chloride Induced Dementia of Alzheimer's Type." CNS & Neurological Disorders - Drug Targets 17, no. 2 (2018): 144–54. http://dx.doi.org/10.2174/1871527317666180309130912.

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Background: Trans-Sinapic Acid is a bioactive compound. Recent studies showed that it has a significant potential to attenuate various chemically induced Neurodegenerative toxicities. Aim: The present study investigates the potential of trans-Sinapic Acid as neuromodulator and its effect on release of Monoamine Oxidase (MAO-A, MAO-B), TNF-α, Acetylcholine esterase Enzyme, in cognitive dysfunctions associated with experimental dementia. Experiment: Aluminium chloride was administered at a dose of 175mg/kg, p.o. for a period of 25 days in rats and then divided into different groups, i.e. Treatme
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Sinha, A. S., U. B. Rao Khandavilli, E. L. O’Connor, B. J. Deadman, A. R. Maguire, and S. E. Lawrence. "Novel co-crystals of the nutraceutical sinapic acid." CrystEngComm 17, no. 26 (2015): 4832–41. http://dx.doi.org/10.1039/c5ce00777a.

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Chen, Chunye. "Sinapic Acid and Its Derivatives as Medicine in Oxidative Stress-Induced Diseases and Aging." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–10. http://dx.doi.org/10.1155/2016/3571614.

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Sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) is an orally bioavailable phytochemical, extensively found in spices, citrus and berry fruits, vegetables, cereals, and oilseed crops and is known to exhibit antioxidant, anti-inflammatory, anticancer, antimutagenic, antiglycemic, neuroprotective, and antibacterial activities. The literature reveals that sinapic acid is a bioactive phenolic acid and has the potential to attenuate various chemically induced toxicities. This minireview is an effort to summarize the available literature about pharmacokinetic, therapeutic, and protective potentia
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Bashir, Ahmad, Matthias Hamburger, Jerome D. Msonthi, and Kurt Hostettmann. "Sinapic acid esters from Polygala virgata." Phytochemistry 32, no. 3 (1993): 741–45. http://dx.doi.org/10.1016/s0031-9422(00)95164-1.

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Barthes, Pascale, Hubert Duran, and Liliane Gorrichon. "Synthesis of [O-14CH3] sinapic acid." Journal of Labelled Compounds and Radiopharmaceuticals 29, no. 7 (1991): 797–804. http://dx.doi.org/10.1002/jlcr.2580290710.

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Gurbuzer, Aslihan. "Investigation of in vitro antimicrobial activities of some hydroxybenzoic and hydroxycinnamic acids commonly found in medicinal and aromatic plants." International Journal of Plant Based Pharmaceuticals 1, no. 1 (2021): 42–47. https://doi.org/10.5281/zenodo.6384189.

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Since hospital-acquired microorganisms are developing more and more resistance to antibiotics used today, researchers are turning to new searches in the treatment of infectious diseases. Unfortunately, unconscious use of antibiotics is another important reason why microorganisms develop resistance to infectious diseases. The aim of this study was to test the antimicrobial activity of some hydroxybenzoic and hydroxycinnamic acids on various gram-positive and gram-negative bacteria and a yeast strain (C. albicans). Agar well diffusion and minimum inhibitory concentration (MIC) tests were applied
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Sorimuthu, Pillai Subramanian. "Sinapic Acid Regulates Glucose Homeostasis by Modulating the Activities of Carbohydrate Metabolizing Enzymes in High Fat Diet Fed-Low Dose STZ Induced Experimental Type 2 Diabetes in Rats." Global Journal of Obesity, Diabetes and Metabolic Syndrome 4, no. 2 (2017): 054–61. https://doi.org/10.17352/2455-8583.000024.

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Diabetes Mellitus is a chronic metabolic disorder arises due to absolute lack of insulin secretion (T1DM) or its action or both (T2DM). Alterations in glucose metabolism in DM are frequently accompanied by impairment in the activities of enzymes that regulate carbohydrate metabolism. Liver is a vital organ that acts as primary site of endogenous glucose production through gluconeogenesis or glycogenolysis. The enzymes that control glucose metabolism in the liver tissue are considered as potential targets for the maintenance of normal glycemic control in diabetic individuals. Search for new dru
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Zych, Maria, Weronika Wojnar, Sławomir Dudek, and Ilona Kaczmarczyk-Sedlak. "Rosmarinic and Sinapic Acids May Increase the Content of Reduced Glutathione in the Lenses of Estrogen-Deficient Rats." Nutrients 11, no. 4 (2019): 803. http://dx.doi.org/10.3390/nu11040803.

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Oxidative stress is believed to be associated with both postmenopausal disorders and cataract development. Previously, we have demonstrated that rosmarinic and sinapic acids, which are diet-derived antioxidative phenolic acids, counteracted some disorders induced by estrogen deficiency. Other studies have shown that some phenolic acids may reduce cataract development in various animal models. However, there is no data on the effect of phenolic acids on oxidative stress markers in the lenses of estrogen-deficient rats. The study aimed to investigate whether administration of rosmarinic acid and
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Hussain, Shabbir, Maleeha Hafeez, Muhammad Riaz, Shazma Massey, Amina Asghar, and Atif Javed. "Antioxidant Properties of Azadirachta Indica Leave Extracts." BioScientific Review 6, no. 2 (2024): 31–43. http://dx.doi.org/10.32350/bsr.62.3.

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Background: Azadirachta Indica is an important medicinal plant commonly found in India, Africa, America, Europe, and many other regions of the world. The current study was designed to investigate the concentrations of important phenolic/flavonoid contents of ethanolic extracts of Azadirachta Indica (neem) leaves (Lahore, Pakistan). Methods: High-performance liquid chromatography (HPLC) analysis revealed the presence of three phenolic compounds (gallic acid, sinapic acid, and caffeic acid) and two flavonols (Myricetin and Kaempferol). The plant extract contained the highest and lowest concentra
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Peyrot, Cédric, Matthieu M. Mention, Fanny Brunissen, and Florent Allais. "Sinapic Acid Esters: Octinoxate Substitutes Combining Suitable UV Protection and Antioxidant Activity." Antioxidants 9, no. 9 (2020): 782. http://dx.doi.org/10.3390/antiox9090782.

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In 2021, Hawaii will permanently ban the use and sale of octinoxate-based sunscreens as studies have shown serious impacts of such UV filters on the coral reef. This ban, which could be generalized to other countries, highlights the extreme need to offer alternative UV filters that are not only effective in terms of sun protection, but also healthy with regards to human health and the environment. In this context, a wide library of p-hydroxycinnamic esters deriving from naturally occurring sinapic acid has been synthesized using a Knoevenagel–Doebner condensation. The UV filtering activities a
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Rajendran, Sridevi, and Chitra Vellapandian. "In-silico profiling of phenolic acids for gallstone prevention: a basis for in-vitro studies in high physical activity and rapid weight loss." Retos 68 (June 25, 2025): 2042–57. https://doi.org/10.47197/retos.v68.116454.

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Background: Cholelithiasis is increasingly seen in individuals with rapid weight loss or high physical stress, such as athletes. Existing therapies like ursodeoxycholic acid have limited efficacy, prompting interest in safer natural options. Aim: To assess the anti-cholelithiatic potential of selected phenolic acids via molecular docking and pharmacokinetic profiling. Methodology: Molecular docking, ADMET analysis, and molecular dynamics simulations were performed for sinapic, p-coumaric, caffeic, and ferulic acids, focusing on targets involved in cholesterol and bile acid regulation (LXR, FXR
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Yamada, Shizuo, Tsutomu Warashina, Osamu Shirota, Yoshihisa Kato, and Toshiyuki Fukuda. "Identification of Sinapic Acid Derivatives from Petit Vert Leaves and Their Effects on Glucose Uptake in C2C12 Murine Myoblasts." Biomolecules 14, no. 10 (2024): 1246. http://dx.doi.org/10.3390/biom14101246.

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Petit vert (scientific name: Brassica oleracea var. gemmifera DC. × Brassica oleracea var. acephala DC.) is a new variety of vegetable created by crossbreeding kale and brussel sprouts (Brassica oleracea species). The present study aimed to identify biologically active compounds in extracts of the outer leaves of Petit vert by purification and to examine their biological activities. The dried and powdered outer leaves of Petit vert were extracted, fractionated, and purified to isolate active compounds. Mass spectrometry (MS) was used to identify the compounds, and nuclear magnetic resonance (N
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Siriamornpun, Sirithon, Jiranan Ratseewo, Niwat Kaewseejan, and Naret Meeso. "Effect of osmotic treatments and drying methods on bioactive compounds in papaya and tomato." RSC Advances 5, no. 24 (2015): 18579–87. http://dx.doi.org/10.1039/c4ra16927a.

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Lučić, Dario, Iva Pavlović, Lidija Brkljačić, et al. "Antioxidant and Antiproliferative Activities of Kale (Brassica oleracea L. Var. acephala DC.) and Wild Cabbage (Brassica incana Ten.) Polyphenolic Extracts." Molecules 28, no. 4 (2023): 1840. http://dx.doi.org/10.3390/molecules28041840.

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Brassicaceae are rich in healthy phytochemicals that have a positive impact on human health. The aim of this study was to analyze the phenolic compounds and antioxidant and anticancer potential of traditional Croatian kale (Brassica oleracea L. var. acephala DC.) and wild cabbage (Brassica incana Ten.) extracts. The phenolic groups and antioxidant activity were determined by spectrophotometry, selected phenolic compounds (ferulic acid, sinapic acid, salicylic acid, kaempferol, and quercetin) were analyzed by LC-MS/MS, and anticancer potential was evaluated in vitro using HeLa cells. The extrac
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Kasparek, Adam, and Bogdan Smyk. "Spectroscopic demonstration of sinapic acid methyl ester complexes with serum albumins." RSC Advances 10, no. 15 (2020): 8810–20. http://dx.doi.org/10.1039/c9ra09980h.

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35

Amarowicz, R., and S. Weidner. "Content of phenolic acids in rye caryopses determined using DAD-HPLC method." Czech Journal of Food Sciences 19, No. 6 (2013): 201–5. http://dx.doi.org/10.17221/6608-cjfs.

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Phenolic compounds were extracted from rye caryopses with 80% (v/v) methanol. Phenolic acids were determined as free compounds and those liberated from soluble esters and glycosides. The analyses were performed using a Waters HPLC system equipped with a diode array detector (DAD). The following free phenolic acids were found: p-coumaric, ferulic and sinapic; the phenolic acids liberated from soluble esters were as follows: vanillic, caffeic, p-coumaric, ferulic and sinapic; and those liberated from soluble glycosides were the following: vanillic, p-coumaric, ferulic and sinapic. In rye caryops
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Stankova, Ivanka, and Maya Spasova. "Hydroxycinnamic Acid Amides with Oxazole-Containing Amino Acid: Synthesis and Antioxidant Activity." Zeitschrift für Naturforschung C 64, no. 3-4 (2009): 176–78. http://dx.doi.org/10.1515/znc-2009-3-404.

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Three hydroxycinnamic acid derivatives conjugated with glycine-containing oxazole were synthesized. The prepared compounds were tested for their antioxidant activity using the 1,1-diphenyl-2-picrylhydrazyl (DPPH・) test. Among the tested hydroxycinnamic acid amides the highest DPPH scavenging activity has been found for the sinapic acid amide.
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37

Beavis, R. C., and J. N. Bridson. "Epitaxial protein inclusion in sinapic acid crystals." Journal of Physics D: Applied Physics 26, no. 3 (1993): 442–47. http://dx.doi.org/10.1088/0022-3727/26/3/015.

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Liu, Hai-Li, Xiang Wan, Xue-Feng Huang, and Ling-Yi Kong. "Biotransformation of Sinapic Acid Catalyzed byMomordica charantiaPeroxidase." Journal of Agricultural and Food Chemistry 55, no. 3 (2007): 1003–8. http://dx.doi.org/10.1021/jf0628072.

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39

Sakushima, Akiyo, Maksut Coşkun, Mekin Tanker, and Nevin Tanker. "A sinapic acid ester from Boreava orientalis." Phytochemistry 35, no. 6 (1994): 1481–84. http://dx.doi.org/10.1016/s0031-9422(00)86880-6.

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40

Paznocht, Luboš, Zora Kotíková, Barbora Burešová, Jaromír Lachman, and Petr Martinek. "Phenolic acids in kernels of different coloured-grain wheat genotypes." Plant, Soil and Environment 66, No. 2 (2020): 57–64. http://dx.doi.org/10.17221/380/2019-pse.

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The content of free, conjugated and bound phenolic acids in 12 wheat (Triticum aestivum L.) genotypes of 4 different grain colours (standard red, yellow endosperm, purple pericarp and blue aleurone) from 2-year field trial was analysed in the present study. Significant increase (8%) in the total phenolic acid content was observed in the dryer year 2017. Five phenolic acids (ferulic, sinapic, p-coumaric, vanillic and 4-hydroxybenzoic) and cis-isomers of ferulic and sinapic acid were determined by HPLC-DAD (high-performance liquid chromatography with a diode-array detector) in grain samples. The
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41

Karamać, Magdalena, and Ryszard Amarowicz. "Inhibition of Pancreatic Lipase by Phenolic Acids -Examination in vitro." Zeitschrift für Naturforschung C 51, no. 11-12 (1996): 903–6. http://dx.doi.org/10.1515/znc-1996-11-1222.

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Abstract The influence of addition 2, 4, 6, 8, and 10 μm of benzoic and cinnamic acids and selected phenolic acids (salicylic, p-hydroxybenzoic, gentisic, protocatechuic, vanillic, syringic, o-coumaric, p-coumaric, caffeic, ferulic, sinapic) on the activity of pancreatic lipase was examined in vitro. The strongest inhibition activities were observed with caffeic, ferulic and benzoic acid, while sinapic and gentisic acids produced the lowest inhibition.
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42

Gurbuzer, Aslihan. "Investigation of in vitro antimicrobial activities of some hydroxybenzoic and hydroxycinnamic acids commonly found in medicinal and aromatic plants." International Journal of Plant Based Pharmaceuticals 1, no. 1 (2021): 42–47. http://dx.doi.org/10.62313/ijpbp.2021.3.

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Since hospital-acquired microorganisms are developing more and more resistance to antibiotics used today, researchers are turning to new searches in the treatment of infectious diseases. Unfortunately, unconscious use of antibiotics is another important reason why microorganisms develop resistance to infectious diseases. The aim of this study was to test the antimicrobial activity of some hydroxybenzoic and hydroxycinnamic acids on various gram-positive and gram-negative bacteria and a yeast strain (C. albicans). Agar well diffusion and minimum inhibitory concentration (MIC) tests were applied
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43

Dhammaraj, Taweesak, Phoobet Kotseekieo, Tunnathon Chotikarn, et al. " In vitro investigation of xanthine oxidase inhibitory and antioxidant activities of 3,4,5-trihydroxycinnamic acid." Journal of Herbmed Pharmacology 13, no. 3 (2024): 439–49. https://doi.org/10.34172/jhp.2024.49420.

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Introduction: Xanthine oxidase inhibitors with strong antioxidant activity are promising candidates for the treatment of gout and reactive oxygen species (ROS)-related disorders. 3,4,5-Trihydroxycinnamic acid (THCA), a natural hydroxycinnamic acid, exhibits strong antioxidant activities. This study investigated its xanthine oxidase inhibitory and antioxidant activities in comparison with sinapic acid, caffeic acid, and allopurinol. Methods: In vitro xanthine oxidase inhibitory assay and a Lineweaver-Burk plot were used to measure enzyme inhibition activity and pattern. A docking study was used
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Olszewska, Monika Anna, Sebastian Granica, Joanna Kolodziejczyk-Czepas, et al. "Variability of sinapic acid derivatives during germination and their contribution to antioxidant and anti-inflammatory effects of broccoli sprouts on human plasma and human peripheral blood mononuclear cells." Food & Function 11, no. 8 (2020): 7231–44. http://dx.doi.org/10.1039/d0fo01387k.

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Rubino, Maria I., Susan D. Arntfield, and James L. Charlton. "Evaluation of Alkaline Conversion of Sinapic Acid to Thomasidioic Acid." Journal of Agricultural and Food Chemistry 44, no. 6 (1996): 1399–402. http://dx.doi.org/10.1021/jf950431e.

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Rubino, M. I., S. D. Arntfield, and J. L. Charlton. "Conversion of phenolics to lignans: Sinapic acid to thomasidioic acid." Journal of the American Oil Chemists' Society 72, no. 12 (1995): 1465–70. http://dx.doi.org/10.1007/bf02577839.

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Sherefedin, Umer, Abebe Belay, Kusse Gudishe, et al. "Investigating the effects of solvent polarity and temperature on the molecular, photophysical, and thermodynamic properties of sinapic acid using DFT and TDDFT." RSC Advances 14, no. 32 (2024): 23364–77. http://dx.doi.org/10.1039/d4ra04829f.

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Sinapic acid (SA) is widely used in cosmetics, foods, and pharmaceuticals due to its antioxidant, anti-inflammatory, neuroprotective, antimicrobial, antifungal, anticancer, and cardioprotective properties.
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TERPINC, Petra, and Helena ABRAMOVIČ. "Oljna pogača navadnega rička (Camelina sativa (L.) Crantz) – neizkoriščeni vir fenolnih spojin." Acta agriculturae Slovenica 107, no. 1 (2016): 243. http://dx.doi.org/10.14720/aas.2016.107.1.22.

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The work includes a comprehensive study of phenolic compounds, their occurrence and identification in the residues after pressing of the oil from camelina seeds of Slovenian origin, i.e. oilcake. In addition, the efficiencies of antioxidant determinations using different methods according to different mechanisms are presented. These data demonstrate that almost all of the phenolic compounds in these seeds remain in the seed oilcake. The following antioxidants were confirmed: sinapine, 4-vinylphenol, 4-vinylguaiacol, 4-vinylsyringol, 4-vinylcatechol, ellagic acid, protocatechuic acid, &lt;em&gt
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Jabbar, Ahmed A. J., Zaenah Zuhair Alamri, Mahmood Ameen Abdulla, Ahmed S. AlRashdi, Soran Kayfi Najmaldin, and Mustafa AbdulMonam Zainel. "RETRACTED: Jabbar et al. Sinapic Acid Attenuate Liver Injury by Modulating Antioxidant Activity and Inflammatory Cytokines in Thioacetamide-Induced Liver Cirrhosis in Rats. Biomedicines 2023, 11, 1447." Biomedicines 13, no. 4 (2025): 862. https://doi.org/10.3390/biomedicines13040862.

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Cherng, Yih-Giun, Cheng-Chia Tsai, Hsien-Hui Chung, Yun-Wen Lai, Shu-Chun Kuo, and Juei-Tang Cheng. "Antihyperglycemic Action of Sinapic Acid in Diabetic Rats." Journal of Agricultural and Food Chemistry 61, no. 49 (2013): 12053–59. http://dx.doi.org/10.1021/jf403092b.

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