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Journal articles on the topic 'Sindh Institute of Urology and Transplantation (Karachi, Pakistan)'

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Published: 4 June 2021

Last updated: 28 July 2025

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1

Raza, Madiha, Furkan Hyder, Noor-us Saba, Hasan Ali Shah, Adeel Hussain, and Syed Farjad Sultan. "Choice of Needle in Spinal Anesthesia among Anesthesiologists in Teaching Hospitals of Sindh." Pakistan Journal of Medical and Health Sciences 16, no. 6 (2022): 71–73. http://dx.doi.org/10.53350/pjmhs2216671.

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Aim: To determine frequency of anesthesiologists practicing pencil- point spinal needles in teaching hospitals of Sindh, Pakistan. Study design: Cross-sectional study. Place and Duration of Study: The Indus Hospital, Aga Khan University Hospital Karachi, Liaquat National Hospital Karachi, Civil Hospital Karachi, Jinnah Postgraduate Medical Centre (JPMC) Karachi, Sindh institute of Urology & Transplantation (SIUT) Karachi, Abbasi Shaheed Hospital Karachi, Ziauddin Hospital Karachi, PNS Shifa Hospital Karachi, Civil Hospital Hyderabad, Chandka Medical College Larkana and Peoples Medical Coll

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2

Balani, Vicky, Naveed Ahmed Mahar, Mohsin Mustafa Memon, Farag Mohsen Saleh Abo Ali, Sara Rasheed Kalwar, and Murli Lal. "Complications of Continent Cutaneous Catheterizable Channel in Adult." Pakistan Journal of Medical and Health Sciences 16, no. 7 (2022): 69–70. http://dx.doi.org/10.53350/pjmhs2216769.

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Aim: To determine the frequency of postoperative complications related to continent cutaneous channel. Study Design: Descriptive study Place and duration of study: Department of Urology, Sindh Institute of Urology & Transplantation, Karachi, Pakistan from 1st August 2019 to 30th November 2021 Methodology: One hundred and seven patients underwent continent catheterizable channel formation via Mitrofanoff principle were included. Each patient was followed in OPD up to 6 months post-procedure to assess the complications i.e. stomal stenosis, stomal incontinence and surgical site infection. Re

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3

Afroz, Mehr, Syed Furqan Zafar, Ejaz Ahmad, and Syed Fazal Akhter. "OUTCOME OF PATIENTS DIAGNOSED WITH END-STAGE RENAL DISEASE REQUIRING INTENSIVE CARE UNIT ADMISSION AT A SINGLE CENTER IN PAKISTAN." PAFMJ 71, no. 3 (2021): 899–903. http://dx.doi.org/10.51253/pafmj.v71i3.3509.

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Objective: To determine the outcome of patients with end-stage renal disease requiring intensive care unit admission at a single center in Pakistan.Study Design: Prospective observational study. Place and Duration of Study: Nephrology Intensive Care Unit of Sindh Institute of Urology and Transplantation, Karachi, Pakistan, from Sep 2018 to Jan 2019. Methodology: After approval from the research advisory board of Sindh Institute of Urology and Transplantation, all consecutive adult patients (≥18 years) of either gender with end-stage renal disease with glomerular filtration rate (GF

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Faizan, Muhammad Aqib, and Tooba Rehman. "Robotic-assisted surgery in Pakistan: its Pros and Cons." Journal of the Pakistan Medical Association 73, no. 12 (2023): 2530–31. http://dx.doi.org/10.47391/jpma.9970.

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Dear Editor, Robotic surgery, is a state-of-the-art technique that enables surgeons to carry out complex procedures with greater accuracy. (1) The system's purpose was to assist surgeons in doing intricate operations while still doing laparoscopy. The system incorporates 3 basic components namely; is 1. Patient’s cart, with robotic arms.; 2. The vision cart incorporated with the hardware to run the system including the camera and the light controls;3. The surgeon’s console, a platform where surgeon controls the movements of the robotic arms. All three are linked by fiber optics. Telesurgery is

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Bangwar, Abdullah, Tanzeel Gazder, Hafiz Muhammed Saad, et al. "Outcomes associated with Percutaneous Nephrolithotomy performed in the supine position." International Journal of Endorsing Health Science Research 12, no. 3 (2024): 125–30. https://doi.org/10.29052/ijehsr.v12.i3.2024.125-130.

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Background: Valdivia first reported safe percutaneous kidney access with a supine patient in 1987-1988. The supine position gained further popularity following the 2007 publication of an international study revealing the Galdakao modification. This study aimed to determine the outcomes associated with percutaneous nephrolithotomy (PCNL) performed in the supine position. Methodology: This descriptive case series study was conducted at the Department of Urology, Sindh Institute of Urology & Transplantation (SIUT), Karachi, Pakistan, from November 7, 2019, to May 6, 2020. Patients were monito

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Shireen Pyarali, Sunil Kumar, Rabeea Saleem, Mehnaz Jabeen, Pardeep Kumar, and Gauhar Sultan. "To Determine The Diagnostic Accuracy of Urinary Nuclear Matrix Protein 22 in Detection of Recurrence of TCC Bladder Among Patients Who Are on Active Surveillance By Taking Cystoscopic Biopsy As A Gold Standard." Pakistan Armed Forces Medical Journal 73, no. 5 (2023): 1491–95. http://dx.doi.org/10.51253/pafmj.v73i5.11156.

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Objective: To determine the diagnostic accuracy of urinary nuclear matrix protein 22 in detection of recurrence of TCC bladder among patients who are on active surveillance by taking cystoscopic biopsy as a gold standard. Study Design: Cross-sectional study.Place and Duration of Study: Departments of Urology, Histopathology and Molecular Biology: Sindh Institute of Urology and Transplantation (SIUT), Karachi Pakistan, from Jan 2021 to Jun 2021. Methodology: Total 83 patients previously biopsy proven bladder carcinoma who are on active surveillance whether or not they have received

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Manzoor Hussain and Saeed Abidi. "Four decades of urolithiasis: What has changed in our practice?" Journal of the Pakistan Medical Association 72, no. 4 (2022): 601–2. http://dx.doi.org/10.47391/jpma.22-25.

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Urolithiasis is the most common urologic disease in Pakistan, which is treated and managed by urologists throughout their careers.1 Its exact prevalence and incidence has never been investigated in the country, but a few rough estimates show the disease prevalence to be 9-15%.2 The oldest study on urolithiasis on 400 patients, was published in 1975, which showed predominantly bladder stone disease accounting for 60% of all cases.3 After the first publication, about 35 papers have been published on this subject from Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan. SIUT

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Ajmal Khan, Tanzeel Gazder, Nisar Ahmed, et al. "Stone clearance rate in patients treated with open surgery versus percutaneous nephrolithotomy for the management of staghorn renal calculi." International Journal of Endorsing Health Science Research 12, no. 1 (2023): 11–17. http://dx.doi.org/10.29052/ijehsr.v12.i1.2024.11-17.

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Background: Urinary calculi, particularly staghorn renal calculi, pose a significant health challenge. Percutaneous nephrolithotomy (PCNL) and open surgery are two distinct surgical interventions employed for treating staghorn renal calculi. This study aimed to compare the stone clearance rates of patients undergoing open surgery versus percutaneous nephrolithotomy at the Department of Urology, Sindh Institute of Urology and Transplantation (SIUT) in Karachi, Pakistan. Methodology: A prospective cohort study was conducted from February 8th to August 7th, 2019. Patients aged 18 to 60 years, dia

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Mengal, Muhammad Hanif, Hina Abbas, Kiran Aamir, and Aamir Ramzan. "INHERITED PROTEIN C AND PROTEIN S DEFICIENCY IN RENAL TRANSPLANT CANDIDATES OF SINDH PROVINCE, PAKISTAN." GJMS Vol 17, No.4, Oct-Dec 2019 17, no. 4 (2019): 117–22. http://dx.doi.org/10.46903/gjms/17.04.1968.

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Background: Thrombophilia is a common risk factor for venous thromboembolism. The objective of this study was to determine prevalence of inherited protein C and protein S deficiency in renal transplant candidates of Sindh Province, Pakistan. Material & Methods: This cross-sectional study was conducted in Department of Pathology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan from 16-10-2010 to 15-4-2011. 300 renal transplant candidates were selected. Candidates with acquired thrombotic disorders, women taking oral contraceptives and patients taking anti-coagulants during

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10

Waqar, Tajammul, Sidra German, and Sajid Bhatti. "Accuracy of eGFR Equation for Predicting Glomeruloar Filtration Rate in Potential Living Kidney Donor." Pakistan Journal of Kidney Diseases 8, no. 1 (2024): 13–20. http://dx.doi.org/10.53778/pjkd81243.

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This Descriptive Cross-Sectional Study, involving 201 patients, conducted at Sindh Institute of Urology and Transplantation (SIUT) Karachi, Pakistan after approval from institute research board. The estimated Glomerular Filtration Rate (eGFR) was calculated using the appropriate equation. Participants were instructed to collect their urine over a 24-hour period in a container devoid of any additives or preservatives. The collected urine specimens were subsequently sent to the institutional laboratory for analysis, with GFR determined based on 24-hour urine creatinine clearance to ensure accura

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Hussain Buriro, Muslim, Tanzeel Gazder, Hafiz Muhammed Saad, et al. "Electrolyte imbalance monitoring following Transurethral Resection of the Prostate: A Descriptive Case Series Study." International Journal of Endorsing Health Science Research 12, no. 3 (2024): 148–53. https://doi.org/10.29052/ijehsr.v12.i3.2024.148-153.

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Background: Transurethral resection of the prostate (TURP) is a widely performed procedure for managing urinary obstruction caused by benign prostatic hyperplasia. Despite its efficacy, TURP often results in postoperative electrolyte imbalances, which require careful monitoring and management to avoid complications. This study addresses a critical gap in the literature by examining the prevalence and severity of these imbalances within the local population of Karachi, Pakistan. Methodology: This descriptive case series study was conducted in the Department of Urology at Sindh Institute of Urol

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Lubna Aman, Madiha Aziz, Noureen Akhter, Muhammed Mubarak, Ali Asghar Lanewala, and Seema Hashmi. "Long-Term Outcome of Children With Steroid-Resistant Nephrotic Syndrome: A Single Center Experience From Pakistan." Pakistan Armed Forces Medical Journal 74, SUPPL-2 (2024): S109—S113. http://dx.doi.org/10.51253/pafmj.v74isuppl-2.6294.

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Objective: To determine the long-term outcome of children with steroid-resistant nephrotic syndrome at a single center in Pakistan. Study Design: Retrospective, observational study. Place and Duration of Study: Pediatric Nephrology Department, Sindh Institute of Urology and Transplantation, Karachi, Pakistan from July 2008 to June 2014. Methodology: The study included 153 children aged 4 months-12 years with steroid-resistant nephrotic syndrome. We collected data at the time of diagnosis and the last follow-up. The data was entered and analyzed by SPSS version 20. Results: Among 153 children,

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Syed Hussain Azhar Rizvi, Fakhir Raza Haidri, Mujtaba Hassan, and Syeda Shaheera Zaidi. "Frequency and spectrum of Post-Intensive Care Syndrome (PICS) in survivors of critical illness in a tertiary care hospital in Pakistan." Professional Medical Journal 31, no. 06 (2024): 932–37. http://dx.doi.org/10.29309/tpmj/2024.31.06.8146.

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Objective: To determine the frequency and spectrum of post-intensive care syndrome (PICS) in survivors of critical illness at a tertiary care hospital of Pakistan. Study Design: Cross-sectional study. Setting: Intensive Care Unit (ICU) of the Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Period: November 2022 to July 2023. Methods: Critical illness survivors aged 18-75 years and discharged from intensive care units ICUs were analyzed. PICS was defined as new or worsening problem(s) in physical, cognitive, or mental health status arising after critical illness and persistin

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14

Nazia Arain, Fakhir Raza Haidri, Bushra Zafar, Ravi Kumar, Abdul Rahman Azam, and Sumera Imran. "Incidence and risk factors of delirium in the intensive care unit of SIUT Karachi." Professional Medical Journal 31, no. 05 (2024): 757–63. http://dx.doi.org/10.29309/tpmj/2024.31.05.8118.

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Objective: To estimate the incidence and risk factors of delirium in intensive care unit (ICU) of Sindh Institute of Urology and Transplantation (SIUT), Karachi. Study Design: Cross-sectional study. Setting: The ICU of SIUT, Karachi, Pakistan. Period: February 2023 to August, 2023. Methods: Patients over 18 years of age who were admitted to the ICU for more than 24 hours were analyzed. Patient with Richmond agitation sedation score (RASS >-2) were assessed for delirium using the confusion assessment method (CAM)-ICU method. Delirium subtypes were also evaluated. Domographic and clinical ris

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Jamil, Sana, Mirza Naqi Zafar, Sulleha Siddiqui, Salma Ayub, and Adeeb-ul-Hassan Rizvi. "Recurrent Urinary Tract Infections in Renal Transplant Recipients: Risk Factors and Outcomes in Low-resource Settings." Saudi Journal of Kidney Diseases and Transplantation 33, no. 6 (2022): 761–73. http://dx.doi.org/10.4103/1319-2442.390256.

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Recurrent urinary tract infections (UTIs) after kidney transplantation are a common problem adversely affecting graft outcomes. This retrospective study aimed to report the frequency and risk factors of recurrent UTI and their impact on graft and patient outcomes in kidney transplant recipients at the Sindh Institute of Urology and Transplantation, Karachi, Pakistan, in January-December 2015. Five-year graft and patient survival rates were compared among different groups using Kaplan-Meier analysis. Of the 251 recipients, 67 developed one episode of UTI. Of these 67, 29 had 76 episodes of recu

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Majid, Zain, Syed Mudassir Laeeq, Muhammad Manzoor ul haq, et al. "Esophageal Motility Disorders in patients with Gastro-Esophageal Reflux Disease diagnosed by using High Resolution Esophageal Manometry- data from the developing world." Asian Journal of Medical Sciences 12, no. 10 (2021): 87–91. http://dx.doi.org/10.3126/ajms.v12i10.38225.

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Background: Gastro-esophageal reflux disease (GERD) has a prevalence of 10-20% in the Western countries while its prevalence amongst the Pakistani population is between 22 to 24%. Esophageal manometry is currently the gold standard for diagnosing esophageal motility disorders. Aims and Objectives: To determine the frequency of esophageal motility disorder in patients with GERD. Materials and Methods: This cross-sectional study was conducted at the department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Patients diagnosed with GERD (defined as ha

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Zain Majid, Syed Mudassir Laeeq, Muhammad Manzoor ul haq, et al. "Esophageal Motility Disorders in patients with Gastro-Esophageal Reflux Disease diagnosed by using High Resolution Esophageal Manometry- data from the developing world." Asian Journal of Medical Sciences 12, no. 10 (2021): 87–91. https://doi.org/10.71152/ajms.v12i10.3653.

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Background: Gastro-esophageal reflux disease (GERD) has a prevalence of 10-20% in the Western countries while its prevalence amongst the Pakistani population is between 22 to 24%. Esophageal manometry is currently the gold standard for diagnosing esophageal motility disorders. Aims and Objectives: To determine the frequency of esophageal motility disorder in patients with GERD. Materials and Methods: This cross-sectional study was conducted at the department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Patients diagnosed with GERD (defined as ha

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18

SM,, Abbas, Siddique M,, Abbas MQ, Farooq MF, Malik S,, and Khan HA. "Role of Dexmedetomidine in Attenuation of Hemodynamic Response to Laryngoscopy - A Dose-Finding Study." Pakistan Journal of Medical and Health Sciences 17, no. 6 (2023): 96–99. http://dx.doi.org/10.53350/pjmhs202317696.

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Aim: Determining efficacy of pre-operative bolus dose of dexmedetomidine 0.75 and 0.5µg/kg as an infusion and compare it with placebo in attenuation of hemodynamic response to laryngoscopy and tracheal intubation (LTI). Design: Double-blind randomized control. Place & duration: Sindh Institute of Urology & Transplantation, Karachi, Pakistan, from August 2019 to August 2021. Methodology: Patients were stratified into three groups. Group A received normal saline (NS), Group B received dexmedetomidine 0.5 μ/kg and Group C received dexmedetomidine 0.75 μ/kg as an infusion over 10 minutes f

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Jawahar Lal Langhani, Zaheer Udin Babar, Sunil Kumar Dodani, Fakhir Raza Haidri, Maryam Mushtaq, and Asma Nasim. "Glycemic control and risk factors of mortality in patients with diabetes mellitus and COVID-19: A single center experience from Pakistan." Professional Medical Journal 31, no. 11 (2024): 1526–31. http://dx.doi.org/10.29309/tpmj/2024.31.11.8072.

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Objective: To highlight the effect of COVID-19 and DM on each other by studying glycemic control and risk factors for mortality. Study Design: Retrospective Observational Review. Setting: Sindh Institute of Urology and Transplantation Karachi Pakistan. Period: March 2020 till March 2021. Methods: Covid-19 diagnosed patients admitted were enrolled. They were divided into DM and non-DM. Demographics, clinical variables and outcome were compared. Glycemic control during hospitalization was noted. Fasting glucose level >120 mg/dl, and random >200 mg/dl were considered as poor glycemic contro

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Rani, Beena, Sunil Kumar Dodani, Zaheer Udin Babar, Maryam Mushtaq, Sanjay Badlani, and Mehreen Fatima. "Treatment outcome of ceftriaxone resistant, Escherichia-coli and Klebsiella spp. bacteremia comparing carbapenem and Beta-lactam/ Beta-lactamase inhibiters in a tertiary care Hospital." Infectious Diseases Journal of Pakistan 34, no. 2 (2025): 136–41. https://doi.org/10.61529/idjp.v34i2.359.

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Background: Carbapenem are recommended for the treatment of Ceftriaxone (CRO) resistant Enterobacterales, however, there are concerns of cost and resistance. Our aim is to compare the outcome of CRO resistant E-coli and Klebsiella bacteremia between Carbapenem and Beta-lactam/beta-lactamase inhibitors (BL/BLI). Material and Methods: This was a prospective cohort study conducted at Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan from October 2021 to June 2022. All adult patients with E coli or Klebsiella spp. bacteremia, CRO resistant and sensitive to both BL/BLI and Ca

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Samejo, K. H., S. K. Kumar, G. Lail, et al. "Frequency of Obesity among Gastroesophageal Reflux Disease Patients." Pakistan Journal of Medical and Health Sciences 15, no. 5 (2021): 1507–10. http://dx.doi.org/10.53350/pjmhs211551507.

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Objective: Gastroesophageal reflux disease (GERD) prevalence ranges from 24% to 35% in Pakistani population. Studies have demonstrated GERD frequency is directly proportional to increasing weight. Thus, the frequency of obesity among gastro esophageal reflux disease patients was determined. Methodology: This cross-sectional study was conducted on outpatients with GERD visiting Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi; from December 2017 to June 2018. Clinical and demographic parameters of study population were recorded. Body mass index (BMI)

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Wadhva, Rajesh Kumar, Muhammad Manzoorul Haque, Nasir Hassan Luck, Abbas Ali Tasneem, Zaigham Abbas, and Muhammad Mubarak. "Diagnostic accuracy of aspartate aminotransferase to platelet ratio index and fibrosis 4 scores in predicting advanced liver fibrosis in patients with end-stage renal disease and chronic viral hepatitis: Experience from Pakistan." Journal of Translational Internal Medicine 6, no. 1 (2018): 38–42. http://dx.doi.org/10.2478/jtim-2018-0008.

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Abstract Objectives The aim was to assess the diagnostic accuracy of APRI and FIB-4 in assessing the stage of liver fibrosis in end stage renal disease (ESRD) patients with chronic viral hepatitis and to compare the two tests with standard tru-cut liver biopsy. Material and Methods The study was conducted at Sindh Institute of Urology and Transplantation Karachi (SIUT) from May 2010 to May 2014. All ESRD patients, being considered as candidates for renal transplantation and in whom liver biopsy was performed were included. Fibrosis stage was assessed on liver biopsy using Ishak scoring system.

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Rehman, Madeeha, Ali Asghar, Afshan Ehsan, Madiha Aziz, Sabeeta Khatri, and Seema Hashmi. "Can Steroid Response in Idiopathic Childhood Nephrotic Syndrome be Predicted? A Single Center Quasi-Experimental Study." Pakistan Armed Forces Medical Journal 72, no. 3 (2022): 980–85. http://dx.doi.org/10.51253/pafmj.v72i3.6346.

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Objective: To predict the role of clinical risk factors and urinary β2-microglobulin levels as a biomarker for steroid-resistant nephrotic syndrome. Study Design: Quasi-experimental study. Place and Duration of Study: Paediatric Nephrology Department, Sindh Institute of Urology and Transplantation, Karachi Pakistan, from Jun 2019 to Nov 2020. Methodology: All children (3 months to 12 years) with either first episode or relapse of the nephrotic syndrome were included. A stored urine sample was used on 100 patients with steroid-sensitive (group-1) and 35 patients with steroid-r

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Ravi Kumar, Fakhir Raza Haidri, Nazia Arain, Adnan Abbas Rizvi, Heeralal, and Ramesh Kumar. "Effect of pre-morbid frailty status on in hospital mortality in critically ill patients." Professional Medical Journal 31, no. 03 (2024): 357–63. http://dx.doi.org/10.29309/tpmj/2024.31.03.7988.

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Objective: To determine the pre-morbid frailty and its association with in-hospital mortality among critically ill patients admitted in intensive care unit (ICU) of a tertiary care hospital. Study Design: Cross-sectional study. Setting: ICU of Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Period: December 2022 to July 2023. Material & Methods: Patients of age 18 years or older, admitted to the ICU were included. Frailty was defined as per Clinical Frailty Scale (CFS). Detailed history was taken to assess frailty status two weeks prior to hospital admission. Patients we

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Yahya, Hina Fatima, Aasia Zubair, Irshad Ali Bajeer, Sabeeta Khatri, Madiha Aziz, and Ali Asghar Lanewala. "Assessing the Accuracy of Diagnostic Tests to Quantify Proteinuria in Nephrotic Children: A Cross-Sectional Study." Pakistan Armed Forces Medical Journal 73, no. 5 (2023): 1350–54. http://dx.doi.org/10.51253/pafmj.v73i5.8256.

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Objective: To assess the diagnostic accuracy of 24-hour proteinuria estimation and urine dipstick-taking spot urine protein creatinine ratio as the gold standard in children with steroid-sensitive nephrotic syndrome. Study Design: Cross-sectional analytical study. Place and Duration of Study: Department of Paediatric Nephrology, Sindh Institute of Urology and Transplantation, Karachi Pakistan, from Oct 2020 to Mar 2021. Methodology: Proteinuric children were enrolled to quantify proteinuria by 24-hour urine protein estimation, spot urine protein creatinine ratio and urine dipstick. Sensitivity

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Shirazi, Bushra, Murk Niaz, and Muhammad Arsalan Khan. "The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional study." Journal of the Pakistan Medical Association 74, no. 4 (2024): 672–76. http://dx.doi.org/10.47391/jpma.9360.

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Objective: To determine the characteristics and risk factors of breast cancer patients in a tertiary care setting. Method: The retrospective, cross-sectional study was conducted at the Sindh Institute of Urology and Transplantation, Karachi, and comprised data of all patients diagnosed with breast cancer from March 2017 to December 2021. Demographic characteristics, clinical presentation, stage of the disease and histopathological characteristics were noted. Data related too all the variables was not available in all cases. Data was analysed using SPSS 23. Results: Of the 690 patients, 683(99%

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Zarkoon, Muhammad Yaqoob, Agha Mohammad Zubair, Syed Rafiuddin Shah, Adil Shah Yousafzai, Umair Akram, and Jamal Mustafa Khan. "Frequency of prostate cancer in patients with abnormal prostate-specific antigen (4–10 ng/mL) and normal digital rectal examination of prostate." Pakistan Journal of Pathology 36, no. 2 (2025): 75–81. https://doi.org/10.55629/pakjpathol.v36i2.917.

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Objective: To determine the frequency of prostate cancer (PCa) in patients with normal digital rectal examination (DRE) and prostate-specific antigen (PSA) levels of 4–10 ng/mL. Material and Methods: This cross-sectional study was conducted at the Sindh Institute of Urology and Transplantation (SIUT), Karachi, from May to November 2023. Eighty patients aged 40–70 years with normal DRE, 4–10 ng/mL PSA levels, and free/total PSA ≥25% were enrolled. Transrectal ultrasound-guided prostate biopsy was performed for histopathological confirmation. Data on demographics, clinical parameters, and biopsy

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Hafeez, Abdul Rauf, Ranjeet Kumar, Nazarul Hassan Jafry, and Muniba Rehman. "Outcomes of severe acute kidney injury requiring renal replacement therapy in renal transplant patients: A single center experience." Pakistan Journal of Medical Sciences 41, no. 3 (2025): 763–68. https://doi.org/10.12669/pjms.41.3.10371.

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Objective: We aimed to assess the renal allograft and patient survival following acute kidney injury requiring dialysis therapy. Methods: We analyzed the medical record of 3000 first living donor kidney transplant performed between 2008 to 2017 for AKI requiring dialysis at Sindh Institute of Urology and Transplantation, Karachi, Pakistan. Patients less than 15 years of age and those AKI events that happened less than three months post renal transplant were excluded. Renal allograft and patient survival were recorded at discharge and one-year post AKI. Recovery of renal functions was assessed

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Abbas, Khawar, Wajiha Musharraf, Mirza Naqi Zafar, Jawahar Lal, Sunil Dodani, and Syed Adibul Hassan Rizvi. "Correlation of lymphocyte subsets and inflammatory biomarkers with disease severity in COVID-19 patients." Journal of the Pakistan Medical Association 74, no. 1 (2023): 78–83. http://dx.doi.org/10.47391/jpma.8583.

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Objective: To determine the correlation of lymphocyte subsets and soluble serum inflammatory biomarkers with disease severity in coronavirus disease-2019 infection. Method: The retrospective study was conducted at the Department of Immunology, Sindh Institute of Urology and Transplantation (SIUI), Karachi, Pakistan from September 1 to November 30, 2021, and comprised data of patients admitted from June to July 2021 who tested positive for coronavirus disease-2019 on the basis of reverse transcription-polymerase chain reaction of nasopharyngeal swab specimens. The patients were categorised into

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Raza, Amber, Syed Haider Nawaz, Rahma Rashid, Ejaz Ahmed, and Muhammed Mubarak. "The correlation of spot urinary protein-to-creatinine ratio with 24-h urinary protein excretion in various glomerulopathies." World Journal of Nephrology 12, no. 5 (2023): 159–67. http://dx.doi.org/10.5527/wjn.v12.i5.159.

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BACKGROUND Proteinuria is an important and well-known biomarker of many forms of kidney injury. Its quantitation is of particular importance in the diagnosis and management of glomerular diseases. Its quantification can be done by several methods. Among these, the measurement of 24-h urinary protein excretion is the gold standard method. However, it is cumbersome, time-consuming, and inconvenient for patients and is not completely foolproof. Many alternative methods have been tested over time albeit with conflicting results. Among the latter, the measurement of urine protein-to-creatinine rati

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Naveed, Sattar Shaikh Anwar Ali Jamali* Ghulam Mustafa Jamali Niaz Hussain Jamali Arslan Ahmer Rajput Ameer Ali Jamali Yash Tanwani Naeem Mustafa Jamali. "FREQUENCY OF VITAMIN D DEFICIENCY IN PATIENTS WITH CHRONIC KIDNEY DISEASE PRESENTING AT SIUT KARACHI." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 3525–32. https://doi.org/10.5281/zenodo.1243869.

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<em>OBJECTIVE: To conclude the frequency of Calciferol (Vitamin D) insufficiency in subjects with CKD (Chronic Kidney Disease) presenting at SIUT Karachi.</em> <em>METHODOLOGY: One hundred patients of both genders visiting Department of Nephrology, SIUT (Sindh Institute of Urology and Transplantation), Karachi, from January 2015 to July 2016, aged above eighteen years with chronic kidney disease underwent Vitamin D levels investigation, and 5 ml of venous blood sample was sent to pathology laboratory for the analysis of Vitamin D, and patients with a level of less than 20 ng/ml was taken as de

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Tunio, Mutahir, Mansoor Rafi, Aamir Maqbool, and Asdarul Haque. "Virtual simulation and treatment verification–merits and demerits: experience at Sindh Institute of Urology and Transplantation (SIUT), Pakistan." Journal of Radiotherapy in Practice 8, no. 3 (2009): 131–36. http://dx.doi.org/10.1017/s1460396909006657.

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Background: The rapid changes in practice of radiotherapy have taken place over the past 5 years in Pakistan. With advent of computed tomography simulator, and multileaf collimators–assisted linear accelerators and electronic portal imaging system, few centres in Pakistan have switched from conventional radiotherapy to modern computer-based technology. Our hospital is first centre in Pakistan which is using virtual simulation since March 2006. We present our experience with list of merits and demerits.Design: Retrospective study.Patient collection: Medical records of all patients who received

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Jawad, F., R. Sheikh, A. Naqvi, and A. Rizvi. "Diabetic nephropathy - an eight year analysis at the diabetes clinic of Sindh Institute of Urology and Transplantation (SIUT), Karachi." Diabetes Research and Clinical Practice 50 (September 2000): 265. http://dx.doi.org/10.1016/s0168-8227(00)80902-x.

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Shuah Ullah, Muntaha Samad, Shariq Bin Yousuf, et al. "Outcome of Arteriovenous Fistula Following Renal Transplantation." Journal of Health and Rehabilitation Research 4, no. 3 (2024): 1–5. http://dx.doi.org/10.61919/jhrr.v4i3.1546.

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Background: Renal transplantation is the preferred treatment for end-stage renal disease (ESRD), but the management of arteriovenous fistulas (AVFs) post-transplant remains controversial due to complications like thrombosis.Objective: To determine the outcome of AVFs following renal transplantation, focusing on the incidence and timing of AVF thrombosis.Methods: This ambi-directional cohort study included 155 patients with ESRD who underwent kidney transplantation at the Sindh Institute of Urology and Transplantation, Karachi, in 2021. All included patients had a functional AVF at the time of

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Iqra Shahid Hussain, Tooba Noor, Quratulain Amir, Washdev Washdev, and Farina Hanif. "PREVALENCE OF MISCONCEPTIONS AND PRESENTATION OF COVID-19 POST-VACCINATION SYMPTOMS AMONG HEALTH CARE WORKERS OF KARACHI, PAKISTAN." Journal of Pakistan Psychiatric Society 19, no. 02 (2022): 12–15. http://dx.doi.org/10.63050/jpps.19.02.145.

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Objectives To determine reasons towards reluctant behavior of health care workers against COVID-19 vaccination and symptoms experienced by vaccinated individuals. Study Design Cross sectional study design. Place and duration of study Dow University of Health Sciences (OJHA Campus), Civil Hospital and Sindh Institute of Urology and Transplant from March 2021 till May 2021. Subjects & methods Altogether 260 samples were recruited and analyzed to investigate the pattern of unwillingness for vaccination, diversity in presentation of symptoms and approaches for its subsidence after administrati

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Abdul Ahad, Usman, Naveed Ahmed Mahar, Harris Hassan Qureshi, and Sara Kalwar. "The lymphocele conundrum: incidence and management in early renal transplants." Journal of the Pakistan Medical Association 75, no. 1 (2024): 9–13. https://doi.org/10.47391/jpma.10623.

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Objective: To assess the incidence of post-transplant lymphocele, identify risk factors, and analyse the effectiveness and outcomes of different management approaches. Method: The prospective, descriptive study was conducted at the Department of Renal Transplant, Sindh Institute of Urology and Transplantation, Karachi, from February 25, 2021, to December 25, 2022, and comprised transplant patients. Ultrasound was performed in all patients presenting with symptomatology attributed to lymphocele. Any peri-graft collection was labelled as lymphocele if creatinine level of aspirated fluid was simi

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Shakeel, Rida, and Sohaib Aftab Ahmad Chaudhry. "A Sustainable Model for Renal Transplantation in Low-Resource Settings: The SIUT Experience." INNOVAPATH 1, Q2 (2025): 7. https://doi.org/10.63501/sgwv1r34.

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Background: Pakistan, with a population of over 240 million, has an estimated end-stage renal disease (ESRD) incidence of 100 per million, yet only 10% of patients access renal replacement therapy due to cost and resource limitations. The Sindh Institute of Urology and Transplantation (SIUT) has pioneered a free, community-supported renal transplantation model since the 1980s. Objectives: This narrative review examines the SIUT model as a sustainable approach to renal transplantation in low-resource settings, highlighting its scalability. Methods: We reviewed operational data, patient outcomes

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Zulfiqar, Zunaira, Fatema Lanewala, Sabeeta Khatri, Irshad Bajeer, Madiha Aziz, and Seema Hashmi. "Steroid induced ocular complications in idiopathic nephrotic syndrome: a cross sectional single center study." Journal of the Pakistan Medical Association 74, no. 2 (2024): 315–19. http://dx.doi.org/10.47391/jpma.10573.

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Objective: To screen children receiving steroids to identify ocular complications and their prevalence. Method: The cross-sectional study was conducted at the Paediatric Nephrology and Ophthalmology departments of the Sindh Institute of Urology and Transplantation, Karachi, from May to October 2022, and comprised patients who received at least 1500mg cumulative steroid dose for a minimum of 3 months. They were screened for steroid-sensitive or steroid-resistant nephrotic syndrome. Ocular examinations, including visual acuity, intraocular pressure, slit-lamp biomicroscopy, lens examination and

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Shah, Hina ,., Sanaa Ahmed, Sadaf Talha, Sumbul Ayaz, Talha Bin Saeed, and Marium Irshad. "Oral Health Related Habits, Knowledge, and Frequency of Dental Floss use among Undergraduate Medical and Dental Students in a Public Health Sector University in Pakistan: A Comparative Study." Pakistan Journal of Medical & Health Sciences 16, no. 10 (2022): 274–78. http://dx.doi.org/10.53350/pjmhs221610274.

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Objective: The current study aimed to evaluate oral health related habits, knowledge, and frequency of dental floss use among undergraduate medical and dental students. Methods: A cross-sectional study was undertaken at two institutes, Sindh Institute of Oral Health Sciences (SIOHS) and Sindh Medical College (SMC) of Jinnah Sindh Medical University (JSMU), Karachi, Pakistan, between March to May 2022. All undergraduate medical and dental students irrespective of gender, cast, creed, or socioeconomic status were eligible to partake in the study. The data on demographics including the age, gende

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Mahar, Naveed A., Harris H. Qureshi, Ghulam M. Kalhoro, et al. "Anatrophic Nehphrolithotomy: Preservation of Renal Function and Stone Clearance Rate." Pakistan Journal of Medical and Health Sciences 16, no. 8 (2022): 54–56. http://dx.doi.org/10.53350/pjmhs2216854.

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Aim: To assess the outcomes of anatrophic nephrolithotomy in terms of stone clearance and change in renal function. Study design: Observational study Place and duration of study: Department of Urology Sindh Institute of Urology & Transplantation, Karachi from 1st January 2016 to 31st December 2021. Methodology: Fifty patients who underwent anatrophic nephrolithotomy from were enrolled. Outcomes were measured in terms of stone clearance, change in pre and post procedure eGFR, serum creatinine and differential renal function on renal scan (MAG-3 scan). Results: There were 30 (60%) males and

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Iqbal, Muhammad Danial, Mushtaq Ahmed, Ahmad Waleed, Tanzeel-Ur-Rahman Gazder, Syed Rabiullah, and Hafiz Muhammad Saad. "Frequency of complications in ultrasound-guided percutaneous nephrostomy: an analysis using the modified clavien classification system." Journal of the Pakistan Medical Association 75, no. 03 (2025): 447–50. https://doi.org/10.47391/jpma.21201.

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Objective: To determine the frequency of complications following percutaneous nephrostomy using the Modified Clavien Classification System in patients with urinary tract obstruction in a tertiary care setting. Method: The observational study was conducted at the Department of Urology, Sindh Institute of Urology and Transplantation, Karachi, from August 18, 2022, to February 17, 2023, and comprised individuals of either gender aged 16-70 years who were experiencing different types of urinary tract obstructions. The patients were subjected to percutaneous nephrostomy, and they were monitored for

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Waleed, Ahmad, Mushtaq Hussain, Muhammad Daniyal, Syeda Zoha Abbas, Tanzeel Gazder, and Kanwal Naz. "Assessing quality of life before and after transurethral resection of the prostate in benign prostatic hyperplasia patients." Journal of the Pakistan Medical Association 74, no. 06 (2025): 935–39. https://doi.org/10.47391/jpma.21189.

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Objective: To compare quality of life scores before and after transurethral resection of the prostate in patients with benign prostatic hyperplasia. Method: The prospective, observational study was conducted at the Urology Department of the Sindh Institute of Urology and Transplantation, Karachi, from September 24, 2021, to March 30, 2022, and comprised consecutive patients who were eligible to undergo transurethral resection of the prostate for benign prostatic hyperplasia. Prior to undergoing definitive surgical therapy, all the patients were evaluated using standardised questionnaires, spec

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Zulfiqar, Mazahir, Manzoor Hussain, Saeed Abedi, Tanzeel-Ur-Rahman Gazder, Syed Rabiullah, and Sanjeet Kumar. "Long-term outcomes of anastomotic urethroplasty for pelvic fracture urethral injury. The experience of a decade at Sindh Institute of Urology and Transplantation." Journal of the Pakistan Medical Association 75, no. 05 (2025): 730–34. https://doi.org/10.47391/jpma.11611.

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Objective: To determine the long-term outcomes of anastomotic urethroplasty in cases of pelvic fracture urethral injury. Method: The retrospective study was conducted at a tertiary care hospital in Karachi, and comprised data from January 1, 2011, to December 31, 2020, related to all patients who had undergone anastomotic urethroplasty for pelvic fracture urethral injury. Clinical data as well as patient-reported outcomes were noted using a predesigned questionnaire. One-year follow-up data of those who expired was not used for analysis. Data was analysed using SPSS 22. Results: Of the 440 pat

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Hassan-Ul-Hassan, Tanzeel-Ur-Rahman Gazder, Nawaz Khan, Abbas Jafri, Asad Shahzad Hassan, and Altaf Hashmi. "Comparative effectiveness of silodosin vs. tamsulosin in treating acute urinary retention in benign prostatic hyperplasia patients." Journal of the Pakistan Medical Association 75, no. 04 (2025): 592–95. https://doi.org/10.47391/jpma.20668.

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Objective: To evaluate the effectiveness of silodosin and tamsulosin in patients with acute urine retention caused by benign prostatic hyperplasia. Method: The prospective cohort study was conducted at the Sindh Institute of Urology and Transplantation, Karachi, from July to December 2022, and comprised male benign prostatic hyperplasia patients with acute urine retention. The patients were divided into group A receiving 0.4mg tamsulosin and group B receiving 8mg silodosin. The catheter was withdrawn after seven days. Trial without catheterisation success was measured by patients’ post-void re

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Chaudhary, Aadil, Zulfiqar Ahmed, Bilal Ahmed, Kaleem Ullah, Mehran Khan Lashari, and Usman Qamar. "Frequency of grading of complications using modified clavien classification system after transurethral resection of prostate." Professional Medical Journal 28, no. 06 (2021): 848–53. http://dx.doi.org/10.29309/tpmj/2021.28.06.6208.

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Objective: To determine the frequency of post-operative complications of transurethral resection of prostate (TURP), in benign prostatic hyperplasia (BPH) patients, using the Modified Clavien Classification System (MCCS). Study Design: Descriptive study. Setting: Urology Department, Sindh Institute of Urology and Transplantation, Karachi. Period: 26th May, 2019 to 25th Nov, 2019. Material & Methods: A total number of 162 patients with benign prostatic hyperplasia planned for TURP were included in this study and Post-operative complications data was collected, and classified according to th

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Hafiz Syed Wahaj Azim Fatmi, Fakhir Raza Haidri, Nazia Arain, Bushra Zafar, Syeda Maheen Fahim, and Mirza Usman Baig. "Pulse index contour continuous cardiac output (PICCO) monitoring in critically ill patients." Professional Medical Journal 31, no. 10 (2024): 1492–97. http://dx.doi.org/10.29309/tpmj/2024.31.10.8314.

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Objective: To evaluate the utility of Pulse index Contour Continuous Cardiac Output (PiCCO) monitoring in critically ill patients. Study Design: Cross-sectional study. Setting: Intensive Care Unti of Sindh Institute of Urology and Transplant, Karachi, Pakistan. Period: October 2022 to March 2023. Methods: Patients presenting with various types of shock, requiring high-dose vasopressors or inotropes, and not responding to initial fluid therapy were analyzed. Demographic details, SOFA score, APACHE score, and invasive hemodynamic parameters using the PiCCO system were documented. Results: Out of

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Kalim, Nazneen, Adnan Ali Baloch, Nida Shafqat, Vijay Kumar, Zamir Ahmad, and Altaf Hassan. "A Randomized Comparative Evaluation Of Effects Of Dexmedetomidine As An Adjuvant With Bupivacainein Supraclavicular Block In Crf Patients Undergoing Basilic Vein Transposition Surgery." Pakistan Journal of Medical and Health Sciences 17, no. 9 (2023): 22–24. http://dx.doi.org/10.53350/pjmhs202317922.

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Aim: To compare analysis of bupivacaine in supraclavicular block with dexmedetomidine bupivacaine in supraclavicular block in chronic renal failure patients undergoing basilica vein transposition surgery. Methodology: Double-blind randomised control trial. Department of Anaesthesia, Sindh Institute of Urology and Transplantation, Karachi, from September 1st, 2021, to February 28th, 2022 Seventy chronic renal failure patients undergoing elective basilic vein transposition surgery were enrolled. Patients were divided into two groups, in which 35 patients in group A received bupivacaine (0.25%) i

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Kalwar, Sara Rasheed, Naveed Mahar, Murli Lal, Mohsin Mustafa Memon, Harris Hassan Qureshi, and Manzoor Hussain. "Evaluation of predictive factors of renal function recovery in renal failure secondary to urinary tract obstruction." Journal of the Pakistan Medical Association 73, no. 6 (2023): 1203–6. http://dx.doi.org/10.47391/jpma.6339.

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Objective: To determine the factors associated with renal function recovery in individuals with kidney failure due to obstruction in the urinary tract. Method: The prospective, descriptive study was conducted July 2020 to August 2021 at the Department of Urology, Sindh Institute of Urology and Transplantation, Karachi, and comprised adult patients of either gender who had renal failure secondary to obstructive urinary tract. Baseline data regarding patients’ variables, including age, gender, duration of symptoms (25 days or 25 days), haemoglobin (9.85g/dl or 9.85g/dl), serum creatinine and ren

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Ullah, Shuah, Laraib Gul, Shariq Bin Yousuf, Bazgha Hassan, Tanzeel-Ur-Rahman Gazder, and Asad Shahzad Hassan. "Evaluating postoperative complications in radical cystectomy and ileal conduit for bladder cancer using the clavien-dindo grading system." Journal of the Pakistan Medical Association 75, no. 07 (2025): 1053–57. https://doi.org/10.47391/jpma.11614.

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Objective: To determine the frequency of postoperative complications after radical cystectomy with ileal conduit surgery in patients diagnosed with urinary bladder cancer. Method: This prospective observational study was conducted at the Department of Urology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, from 30TH December 2019 to 30TH June 2020, following approval from the SIUT Ethical Review Board. The study comprised patients aged 25-70 years diagnosed with urinary bladder cancer who underwent elective radical cystectomy with ileal conduit. Complications were compared wit

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Muhammad Fayyaz, Naveed Ahmed Mahar, Harris Hassan Qureshi, Sara Kalwar, Usman Abdul Ahad, and Altaf Hashmi. "Anticipating bladder outlet obstruction in enlarged prostate: non-invasive clinical parameters as predictive tools." Journal of the Pakistan Medical Association 74, no. 06 (2025): 888–91. https://doi.org/10.47391/jpma.11443.

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Objective: To determine the positive predictive value of clinical evaluation with maximum flow rate, prostatic volume and international prostate symptom score in predicting bladder outlet obstruction due to prostatic enlargement. Method: The cross-sectional, prospective study was conducted at the Urology Department of the Sindh Institute of Urology and Transplantation, Karachi, from September 2021 to May 2023, and comprised male patients with refractory lower urinary tract symptoms in whom surgical intervention had been planned. All patients with prostate volume >40ml, maximum flow rate &lt

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