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Journal articles on the topic 'Single tax of 4 groups'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Glazunova, Irina. "PROBLEM ASPECTS OF FORMATION OF THE LEGAL INSTITUTE OF CONSOLIDATED TAXPAYERS’ GROUPS IN RUSSIA." Law Enforcement Review 1, no. 4 (2018): 56–65. http://dx.doi.org/10.24147/2542-1514.2017.1(4).56-65.

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The subject. The article is devoted to the prerequisites of the emergence and essential characteristics of the institution of consolidated taxpayers’ groups in Russia and abroad, revealing of advantages and disadvantages of the legal regulation of the creation and operation of consolidated groups of payers of corporate profits tax, analyzing results and directions of the development of tax consolidation in Russian Federation.The purpose of the article is to identify positive and negative aspects of the functioning of the institution of consolidated taxpayers’ groups in Russia with the establis

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Loboda, N. O., O. М. Chabaniuk, and Y. O. Mosolova. "Simplified Taxation System as a Microeconomic Fiscal Regulator." Business Inform 4, no. 519 (2021): 228–34. http://dx.doi.org/10.32983/2222-4459-2021-4-228-234.

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The article considers the specifics and features of application of the simplified taxation system in Ukraine. Small business entities can apply either general or simplified taxation system. On the basis of generalizations of literary sources and current practice, the advantages and disadvantages of the simplified system at the present stage of economic development are determined. The biggest advantages of the simplified taxation system are tax advantages, which consist in the absence of the obligation to pay certain types of taxes, as well as a simplified system of accounting and reporting for

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Del Priore, Giuseppe, Perry Wayne Grigsby, Christine M. Gan, and Todd D. Tillmanns. "In vitro chemoresponse assay for patients with cervical cancer." Journal of Clinical Oncology 30, no. 15_suppl (2012): e15514-e15514. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e15514.

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e15514 Background: Chemotherapy is used in cervical cancer as neoadjuvant, chemosensitization with radiation, and upon recurrence. This study reports the results of an in vitro chemoresponse assay (ChemoFx, Precision Therapeutics) in primary, metastatic, or recurrent cervical cancer. Methods: Between 8/8/06- 6/2/10, 557 tumor specimens were received and 353 (63%) were successfully assayed. Status (primary, metastatic or recurrent) and histology (squamous 58%; adenocarcinoma 20%; adenosquamous 6%; neuroendocrine 5%; and other12%) was confirmed in 273 for this report. Single agents tested includ

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OLIYNYK, Oleksandr, Ganna MOROZOVA, and Valery SHEVCHENKO. "INNOVATION OF DEVELOPMENT OF CERTAIN BRANCHES OF THE AGRICULTURAL SECTOR AND ITS FINANCIAL SUPPORT." "EСONOMY. FINANСES. MANAGEMENT: Topical issues of science and practical activity", no. 4 (54) (December 19, 2020): 54–66. http://dx.doi.org/10.37128/2411-4413-2020-4-4.

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The article considers methodological approaches to assessing the innovative development of the agricultural sector, which allowed to divide them into two groups: universal, which can be used to assess the innovative development of any type of enterprise, and specific, which are specific to certain types of enterprises depending on their activities , in particular agricultural. It is established that the most common methods of assessing the innovativeness of enterprise development are: determining the sensitivity of the enterprise to innovation, assessment of its innovation potential or innovat

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OVDII, Olena, and Tetiana REDZIUK. "FEATURES OF THE FINANCIAL AND TAX ACCOUNTING OF THE VALUE ADDED TAX IN THE TRANSITION TO THE SIMPLIFIED TAXATION SYSTEM IN THE CONDITIONS OF MARITAL STATE IN UKRAINE." Herald of Khmelnytskyi National University. Economic sciences 308, no. 4 (2022): 38–43. http://dx.doi.org/10.31891/2307-5740-2022-308-4-6.

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The purpose of the article. To systematize changes, innovations and peculiarities of financial and tax accounting of VAT during the transition to a simplified taxation system in the conditions of martial law in Ukraine. The following research methods were used for the purposes of the research: content analysis, comparative analysis, and logical generalization methods were used by the authors to formulate the chosen topic and purpose of the research, critical analysis of scientific and specialized literature; the method of scientific abstraction was used in order to highlight the peculiarities

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Liu, Jodi L., Federico Girosi, Ruolin Lu, and Christine Eibner. "Household Health Care Payments Under Rate Setting, Spending Growth Target, and Single-Payer Policies." JAMA Health Forum 5, no. 6.9 (2024): e241932. http://dx.doi.org/10.1001/jamahealthforum.2024.1932.

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ImportanceHouseholds have high burden of health care payments. Alternative financing approaches could reduce this burden for some households.ObjectiveTo estimate the distribution of household health care payments across income under health care reform policies.Design, Setting, and ParticipantsCross-sectional study with microsimulation used nationally representative data of the US population in 2030. Civilian, noninstitutionalized population from the 2022 Current Population Survey linked to expenditures from the 2018 and 2019 Medical Expenditure Panel Survey and 2022 National Health Expenditure

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Khlestova, K. S., and A. S. Voronov. "RISK MANAGEMENT FOR SINGLE-INDUSTRY TERRITORIES WITHIN A FRACTAL APPROACH." Intelligence. Innovations. Investment, no. 4 (2021): 36–45. http://dx.doi.org/10.25198/2077-7175-2021-4-36.

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The article presents the results of the author’s study of single-industry territories within the framework of the fractal approach. The relevance of the researching is since the risk management of mono-profile is one of the most important elements of differentiated management impact on the socio-economic system of the territory to ensure its harmonious development. The aim of the work is to assess the risks of single-industry using elements of a fractal approach to the study of the social and economic space of mono-territories. The methodological basis for the application of the fractal approa

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Linder, Matthias, David Grundmann, Caroline Kellner, et al. "Intravascular Lithotripsy-Assisted Transfemoral Transcatheter Aortic Valve Implantation in Patients with Severe Iliofemoral Calcifications: Expanding Transfemoral Indications." Journal of Clinical Medicine 13, no. 5 (2024): 1480. http://dx.doi.org/10.3390/jcm13051480.

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(1) Background: Transfemoral transcatheter aortic valve implantation (TAVI) has become the standard treatment for most patients with severe symptomatic aortic stenosis. Intravascular lithotripsy may facilitate transfemoral TAVI (IVL-TAVI) even in patients with severely calcified iliofemoral disease. We assessed technical aspects and clinical outcomes of this novel approach compared to alternative transaxillary access (TAX-TAVI). (2) Methods: IVL-TAVI was performed for severe iliofemoral calcifications precluding standard transfemoral access in 30 patients from 2019 to 2022 at a single academic

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Tremel, Wolfgang, and Karl-Ludwig Stork. "[TaTe4]4[PtI6]I2, ein neues quaternäres Tellurid-Iodid mit Kettenstruktur / [TaTe4]4[PtI6]I2, A New Quaternary Telluride-Iodide with Chain Structure." Zeitschrift für Naturforschung B 48, no. 9 (1993): 1155–60. http://dx.doi.org/10.1515/znb-1993-0901.

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[TaTe4]4[PtI6]I2 was synthesized from the elements at 680°C. Its crystal structure was determined using single crystal methods. The structure of the quasi one-dimensional compound [TaTe4]4[PtI6]I2 (P1̄, Z = 1, a = 16.831(1), b = 17.740(1), c = 19.018(1)Å, α = 93.57°, β = 94.08°, γ = 102.09°) consists of Ta(Te2)2 chains separated by PtI6 groups and I atoms. The formal oxidation state assignment [(Ta5+)(Te22-)2]4[(Pt4+)(I-)6](I-)2 indicates that semiconducting properties are to be expected for this material.

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SHEVCHENKO, Liubov, and Anastasiia KULISH. "Peculiarities of accounting and taxation at agricultural enterprises." Economics. Finances. Law 11, no. - (2022): 19–21. http://dx.doi.org/10.37634/efp.2022.11.4.

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The paper is devoted to determining the features of accounting and taxation at agricultural enterprises, principles, advantages and disadvantages for further improvement. Agriculture is one of the leading branches of our country's economy. In recent years, there have been significant changes in the organization of accounting of agricultural enterprises. A number of changes to the legislative and regulatory acts regulating accounting at these enterprises were put into effect. The taxation system on which agricultural enterprises can be subject to changes has also undergone changes, in particula

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Лебедева, Екатерина Владимировна. "О правовом статусе холдингов в Российской Федерации". Азиатско-Тихоокеанский регион: экономика, политика, право 26, № 4 (2024): 139–48. https://doi.org/10.24866/1813-3274/2024-4/139-148.

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The peculiarities of the historical development of Russia gave rise to the emergence of special subjects of legal relations, which are interconnected legally and economically legal entities, controlled and managed in a certain way. Currently in Russia, most large businesses are represented by associations of legal entities, which are referred to as holdings. Meanwhile, the current civil legislation does not directly determine the existence of such an entity as a holding. At the same time, other branches of legislation (antimonopoly, tax, administrative, etc.) certain groups of subjects of lega

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Krasnonosova, O. M., and R. V. Kharchenko. "State Policy Tools in the Field of Support and Stimulation of Small Business Development." PROBLEMS OF ECONOMY 4, no. 46 (2020): 42–47. http://dx.doi.org/10.32983/2222-0712-2020-4-42-47.

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The definition of state policy on business regulation is understood here in accordance with the current Commercial Code of Ukraine, namely: it is a system of economic, social, organizational, legal and political support of a favorable business climate so as to form and develop small business. This understanding allows us to distinguish three blocks within state policy. The first block includes fiscal components of economic relations, primarily related to financing (this block includes monetary policy, investment policy, antitrust policy, depreciation policy, innovation policy); the second bloc

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13

Dedy Pratama, Hendro Sudjono Yuwono, Rudi Supriyadi, Herry Herman, Fachreza Aryo Damara, and Avicenna Akbar. "Antioxidant Properties of Curcumin and Its Impact on Arteriovenous Fistula Maturation in End-Stage Kidney Disease Patient with Diabetes Mellitus Type 2." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 7624–29. http://dx.doi.org/10.26452/ijrps.v11i4.4107.

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The risk of maturation failure in arteriovenous fistula (AVF) remains high. Curcumin poses antioxidant effects may enhance AVF maturation. This study evaluates the antioxidant effect of Curcumin on AVF maturation among type 2 diabetic patients (T2DM) with end-stage renal disease (ESRD). This was a single-blinded, randomized controlled trial conducted in three tertiary hospitals in Jakarta, Indonesia. Patients underwent the first hemodialysis. A total of 67 patients divided into groups of Curcumin, acetylsalicylic acid, and placebo. After 4 weeks, TAC level among the curcumin group was signific

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Yang, Liufeng, Yuanyue Li, Qian Hu, Tingting Zhang, Mengyue Cui, and Jie Zhang. "Investigating the association between BRCA1/2 copy number variation and homologous recombination deficiency score in ovarian cancer: A cross-sectional study." Journal of Clinical Oncology 41, no. 16_suppl (2023): e17584-e17584. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e17584.

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e17584 Background: PARP inhibitors (PARPi) have shown significant clinical benefit as maintenance or systematic therapy in patients with ovarian cancer (OC) with BRCA1/2 mutation or positive homologous-recombination deficiency (HRD) status. However, patients with BRCA1/2 mutation not only showed better efficiency of PARPi, but also higher HRD score than other populations. Therefore, patients with BRCA1/2 mutation have received much attention. However, there are many kinds of variants in BRCA1/2 of OC patients. The purpose of this study is to explore the distribution of BRCA1/2 copy number vari

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15

Erten, Fusun, Besir Er, Ramazan Ozmen, et al. "Effects of Integrated Extracts of Trigonella foenum-graecum and Asparagus racemosus on Hot Flash-like Symptoms in Ovariectomized Rats." Antioxidants 14, no. 3 (2025): 355. https://doi.org/10.3390/antiox14030355.

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Vasomotor symptoms, such as hot flashes (HFs), commonly affect women during menopause, leading to a reduced quality of life. The current study evaluates the combined effect of active components Asparagus racemosus (AR) and Trigonella foenum-graecum (TFG) in a single oral formulation (IAT) for alleviating menopausal symptoms in ovariectomized rats. Following bilateral ovariectomy, the animals were randomly assigned to nine groups: (1) Control, (2) Ovariectomy (OVX), (3) OVX+TA1 (TA: Combination of Trigonella and Asparagus; TFG 30 mg/kg + AR 30 mg/kg), (4) OVX+TA2 (TFG 30 mg/kg + AR 15 mg/kg), (

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16

KURU, MUSHAP, CIHAN KACAR, HASAN ORAL та ін. "Effect of two prostaglandin F2α injections administered 24 hours apart on the pregnancy rate of Simmental cows subjected to the Ovsynch or Ovsynch + Controlled internal drug release (CIDR) protocols". Medycyna Weterynaryjna 76, № 10 (2020): 6451–2020. http://dx.doi.org/10.21521/mw.6451.

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The aim of the present study was to determine the effects of one or two doses of prostaglandin F2α (PGF) on the pregnancy rate (PR) in Simmental cows subjected to the Ovsynch or Ovsynch + Controlled internal drug release (CIDR) protocols. On d 0, 100 µg gonadorelin diacetate tetrahydrate (GnRH) was injected into cows in group 1 (n = 50) and group 2 (n = 40) and CIDR was intravaginally inserted. On d 7, 25 mg dinoprost tromethamine (PGF2α, PGF) was administered, and GnRH was injected 56 h later. Fixed-time artificial insemination (TAI) was performed 16 h after GnRH injection. In group 3 (n = 62

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17

Padhiar, Bela B., and Sreelakshmi T S. "A therapeutic evaluation of various modalities of treatment of keloid-A randomized open label study." IP Indian Journal of Clinical and Experimental Dermatology 9, no. 2 (2023): 109. http://dx.doi.org/10.18231/j.ijced.2023.018.

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Keloid and hypertrophic scar are the result of abnormal growth of fibrous tissue following healing of a cutaneous injury in predisposed individuals. Some treatment options are pressure garments, radiation therapy, excision, intralesional injections, cryotherapy, silicone gel dressing and lasers though no single modality is completely effective.To study the efficacy, to compare and to study the adverse effects of 4 different modalities of treatment of keloid namely, Intralesional triamcinolone acetonide (TAC), Intralesional triamcinolone acetonide and 5-fluoro uracil (5-FU), Intralesional triam

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Zhou, Qin, Yu-feng Gao, Xiao-miao Zhao, Fa-ming Pan, and Xu Li. "Single Nucleotide Polymorphisms rs2227284, rs2243283 and rs2243288 in the IL-4 Gene Show no Association with Susceptibility to Chronic Hepatitis B in a Chinese Han Population." Infection International 3, no. 1 (2014): 16–21. http://dx.doi.org/10.1515/ii-2017-0068.

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Abstract Objective To investigate the relationship between single nucleotide polymorphisms (SNPs) of the interleukin-4 (IL-4) gene and outcome of hepatitis B virus (HBV) infection in a Chinese Han population. Methods Total of 501 patients with chronic hepatitis B virus (HBV) infection and 301 controls with selflimiting HBV infection were studied. Three tag SNPs in the IL-4 gene (rs2227284G/T, rs2243283C/G and rs2243288A/G) were genotyped by the Multiplex snapshot technique. The genotype and allele frequencies were calculated and analyzed. Results The three SNPs showed no significant genotype/a

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Karamık, Kaan, Mehmet Kısaarslan, Hakan Anıl, and Nihat Ateş. "Efficacy of tamsulosin versus silodosin as medical expulsive therapy on stone expulsion in patients with distal ureteral stone: A retrospective single center study." Yeni Üroloji Dergisi 18, no. 1 (2023): 1–7. http://dx.doi.org/10.33719/yud.2023;18-1-1118339.

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Objective: This study aimed to compare the efficacy of tamsulosin and silodosin as medical expulsive therapy in patients with symptomatic uncomplicated distal ureteric stones. Material and Methods: The data of adult patients who had distal ureteric stones in size between 4 and 10 mm and were treated with medical expulsive therapy between June 2019 and January 2022 were retrospectively documented. Patients were divided into two groups. Patients in Group 1 received silodosin 4 mg, and Group 2 received tamsulosin 0.4 mg. Therapy was given for a maximum of 3 weeks. Stone expulsion rate, time to st

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Pancarci, Sükrü Metin, Örsan Güngör, Osman Harput, and Oguz Calisici. "Effect of One-Day Delaying CIDR Administration in 5-Day Cosynch Protocol in Dairy Heifers." Animals 11, no. 5 (2021): 1402. http://dx.doi.org/10.3390/ani11051402.

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Effect of one-day delaying progesterone administration at the beginning of 5-day Cosynch protocol was investigated in Holstein heifers for the first artificial insemination (AI). Heifers received a synchronized ovulation and timed AI (TAI) with CIDR inserted on day (d) 0 (CIDR-5; n = 206) or d 1 (CIDR-4; n = 192). In both group, GnRH was administered on d 0 followed by a single PGF2α injection and CIDR removal five days later from GnRH. On d 8, TAI and GnRH administration were concurrently conducted. Heifers detected in estrus up to 24 h prior to TAI were inseminated without GnRH administratio

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Kortman, Maud, Maarten Kreek, Anouk de Jong, et al. "NCOG-19. FUNCTIONAL OUTCOME AFTER RE-RESECTION OF TUMOR PROGRESSION, MIXED LESION OR TREATMENT-ASSOCIATED EFFECTS IN IRRADIATED DIFFUSE GLIOMAS (GRADE 2-4): IDENTIFYING CLINICAL AND RADIOLOGICAL DETERMINANTS." Neuro-Oncology 26, Supplement_8 (2024): viii228. http://dx.doi.org/10.1093/neuonc/noae165.0901.

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Abstract In cases of radiological progression in patients with irradiated diffuse gliomas, recurrence-resection is frequently performed. In our previous histological evaluation 19% of these re-resection cases were found to be due to treatment-associated effects (TAE). Limited literature substantiating which patients will benefit from surgery and which patients will deteriorate postoperatively is available. We aim to (a) describe the functional outcomes after re-resection of an irradiated diffuse glioma in adult patients; (b) compare early functional outcomes between patients with TAE versus pr

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Shao, Xiangzhi, Bing Chen, Lielie Zhu, et al. "The Effects of Adding Di-Tan Decoction (DTD) and/or Electroacupuncture (EA) to Standard Swallowing Rehabilitation Training (SRT) for Improving Poststroke Dysphagia (PSD): A Pilot, Single-Centred, Randomized Trial." Evidence-Based Complementary and Alternative Medicine 2022 (December 8, 2022): 1–13. http://dx.doi.org/10.1155/2022/2011597.

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Objectives. To evaluate the effect of adding Di-tan decoction (DTD) and/or electroacupuncture (EA) to standard swallowing rehabilitation training (SRT) on improving PSD. Methods. In total, 80 PSD patients were enrolled and randomly assigned to the DTD, EA, DTD + EA or control group at a 1 : 1 : 1 : 1 ratio. All patients received basic treatment and standard SRT. The DTD group received DTD orally, the EA group received EA, the DTD + EA group received both DTD and EA simultaneously, and the control group received only basic treatment and standard SRT. The interventions lasted for 4 weeks. The ou

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Czarnecka, Paulina, Kinga Czarnecka, Teresa Baczkowska, Beata Lagiewska, and Magdalena Durlik. "Real-life comparison of efficacy and safety profiles of two prolonged-release tacrolimus formulations in de novo kidney transplant recipients: 24 months of follow-up." PLOS ONE 18, no. 1 (2023): e0278894. http://dx.doi.org/10.1371/journal.pone.0278894.

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Introduction Calcineurin inhibitors constitute a cornerstone of immunosuppressive therapy in kidney transplant recipients. There are two main formulations of tacrolimus (Tac) which exhibit a prolonged-release mode of action: Advagraf® (MR-4) and Envarsus® (LCPT). However, they are not bioequivalent. Data comparing both once-daily prolonged-release formulations of Tac are insufficient. Objective The aim of the study was to compare safety and efficacy profiles of once-daily LCPT and MR-4 formulations of tacrolimus in adult kidney transplant recipients. Patients and methods An observational, coho

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Rudakova, Olga V., Nelli N. Orlova, and Yulia N. Kovalenko. "Confidence as Sociocultural and Economic Phenomenon." Economic Environment, no. 4 (46) (2023): 19–27. http://dx.doi.org/10.36683/2306-1758/2023-4-46/19-27.

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The important role of confidence in public life consists in possibility of the effectiveness increase of all social phenomena and processes. In addition, confidence acts as a leading element of the mechanism of society integration into a single system. The purpose of the study is to analyze the role of confidence in culture transmission, which is a social experience accumulated in the process of people's joint activities. Confidence is an integral part of society's life and manifests itself in all its spheres, including economy. The research uses theoretical and empirical methods, in particula

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Ashley, M., A. Sisodiya, M. McEwan, J. McAughey, and K. Prasad. "Comparison of Mouth Level Exposure to ‘Tar’ and Nicotine in Smokers of Normal and Superslim King Size Cigarettes in Romania." Beiträge zur Tabakforschung International/Contributions to Tobacco Research 24, no. 6 (2011): 277–88. http://dx.doi.org/10.2478/cttr-2013-0908.

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AbstractFilter analysis methodology can be used to estimate smokers’ mouth level exposure (MLE) to ‘tar’ and nicotine from spent cigarette filters. Variation in smoking behaviour and cigarette design are known to have an impact on the range of ‘tar’ and nicotine MLE. Most ‘King Size’ (KS) cigarettes have a circumference of about 25 mm and are 83-84 mm long, with filters 20-27 mm in length. Recently, a slimmer format, described as a ‘King Size Superslim’ (KSSS), with a circumference of 17 mm, has become popular in several countries. Although several studies have estimated the MLE to ‘tar’ and n

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Suat, Çakına, Ceyda İrkin Latife, and Öztürk Şamil. "The Cardioprotective Effect of N-acetylcysteine on Doxorubicin Induced Cardiotoxicity in Heart Tissue of Rats." INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND ANALYSIS 07, no. 01 (2024): 159–63. https://doi.org/10.5281/zenodo.10527135.

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Doxorubicin (DOX) is a chemotherapeutic agent and is widely used in cancer treatment. There are some studies suggesting oxidative stress-induced toxic changes in the liver due to DOX administration. The aim of this study was to reveal the oxidative damage of DOX in liver tissue at molecular level and to evaluate the protective effect of N-acetylcysteine (NAC) against DOX oxidative damage. Twenty four rats weighing 150-200 g were randomly divided into four equal groups; group I : control, group 2: received a single dose of DOX, group 3: received NAC for 28 days and group 4: received a single do

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Umoh, Idongesit Bassey, and Imoh Emmanuel Ukoh. "Evaluation of Body Weight, Serum Glucose Level, and Oxidative Stress Parameters of Streptozotocin-Induced Diabetic Rats Administered Insulin and Alkaloid Leaf Extract of Jatropha tanjorensis." African Journal of Medicine, Surgery and Public Health Research 2, no. 3 (2025): 413–35. https://doi.org/10.58578/ajmsphr.v2i3.6813.

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This study investigates the therapeutic potential of alkaloid leaf extract of Jatropha tanjorensis (ALEJT) in managing diabetes mellitus (DM), particularly its effects on body weight, serum glucose, and oxidative stress parameters, in comparison to insulin. DM is associated with weight loss and elevated oxidative stress, prompting the need for alternative therapies. Forty female albino rats (150–200 g) were divided into four groups (n = 6). Group 1 served as the normal control, while diabetes was induced in Groups 2–4 via a single intraperitoneal injection of streptozotocin (STZ, 80 mg/kg). Ra

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Payne, E., JF Smith, BC Cope, and LT McGowan. "Studies on the role of liver cytochrome P-450 and oestradiol metabolism in the effects of nutrition and phenobarbital on ovulation rate in the ewe." Reproduction, Fertility and Development 3, no. 6 (1991): 725. http://dx.doi.org/10.1071/rd9910725.

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Coopworth ewes were differentially fed to produce 60 heavy (62 kg) and 80 light (45 kg) ewes. They were then fed a low protein (100 g protein kg-1 dry matter) pelleted ration. On Day 7 of the oestrous cycle after synchronization the following treatments were commenced in groups of 10 ewes: 4 low liveweight groups received low protein (LP), high protein (HP; 230 g protein kg-1 dry matter), LP + phenobarbital (PB; 1 g per os per day in gelatin capsules for 10 days) and LP + triacetyloleandomycin (TAO, 0.5 g day-1 in capsule for 10 days); while 3 high liveweight groups received LP, HP and HP + ca

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Rushing, Calvin J., Bryon J. McKenna, Gregory C. Berlet, and Antonio M. Malloy McCoy. "Lateral Instability in Total Ankle Arthroplasty: A Comparison Between the Brostrom-Gould and Anatomic Lateral Ankle Stabilization (ATLAS)." Foot & Ankle Orthopaedics 7, no. 1 (2022): 2473011421S0005. http://dx.doi.org/10.1177/2473011421s00056.

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Category: Ankle; Sports; Other Introduction/Purpose: Lateral ankle instability is not uncommon after osseous cuts and soft tissue releases are performed during Total Ankle Arthroplasty (TAA), particularly with varus malalignment. The purpose of the present study was to compare the outcomes of ankles that underwent TAA with concurrent Brostrom-Gould (BG) or Anatomic Lateral Ankle Stabilization (ATLAS) at a minimum of 1-year follow-up. Methods: Thirty-eight TAA's underwent BG (21 INFINITY, 4 CADENCE) or ATLAS (13 INBONE-2) between August 2015 and February 2019 at a single institution and were at

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H Zander, Richard. "On the Origin of Taxa." Journal of Theoretical Physics & Mathematics Research 3, no. 1 (2025): 01–20. https://doi.org/10.64030/3065-8802.03.01.06.

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The fundamental structure of the Biosphere how taxa resiliently survive millions of years—can be based on principles and laws of physics, particularly through analogy with relationships of classical mechanics and the Pareto alpha index matching a fractal dimension. Like physical conservation laws, these controlling elements survive intact during system change. Arguments are advanced to support the hypothesis of a quadratic origin of taxa based on symmetry breaking and mirror parity, which is extensible from bryophytes to all taxonomic groups. A minimally monophyletic group is one ancestral spe

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Huang, Yan, Peifang Jiang, Jiazheng Li, et al. "Single-Cell RNA Sequencing Unveils the Hallmarks of Populations at Different Stages of HTLV-1 Infection." Blood 138, Supplement 1 (2021): 3323. http://dx.doi.org/10.1182/blood-2021-152438.

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Abstract Background Adult T-cell leukemia-lymphoma (ATL) is an aggressive mature T-cell neoplasm caused by human T -cell leukemia virus type 1 (HTLV-1). Up to 5% of infected individuals develop to ATL. HTLV-1 preferentially infects CD4 + T cells, and stimulates cell proliferation and prevents cell death by apoptosis. The viral oncogene-encoded proteins, Tax and HBZ, play important roles in viral infection and cell immortalization. However, the host factor of developing from carrier to patient is not clear. Results To characterize the heterogeneity of ATL patients, we performed single-cell RNA-

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Faisal Lutfi, Mohamed, Abdel-Moneim Hafez Abdel-Moneim, Ashwag Saleh Alsharidah, et al. "Thymoquinone Lowers Blood Glucose and Reduces Oxidative Stress in a Rat Model of Diabetes." Molecules 26, no. 8 (2021): 2348. http://dx.doi.org/10.3390/molecules26082348.

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The aim of the present study was to assess the short-term effects of Thymoquinone (TQ) on oxidative stress, glycaemic control, and renal functions in diabetic rats. DM was induced in groups II and III with a single dose of streptozotocin (STZ), while group I received no medication (control). The rats in groups I and II were then given distilled water, while the rats in group III were given TQ at a dose of 50 mg/kg body weight/day for 4 weeks. Lipid peroxidase, nitric oxide (NO), total antioxidant capacity (TAC), glycated haemoglobin (HbA1c), lipid profiles, and renal function were assessed. Mo

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CAKINA, S., T. GULYASAR, A. ÖZEN, et al. "Comparison of Protective Effects of Melatonin and Amifostine on Radiation-Induced Renal Oxidative Stress in Rats." Journal of the Hellenic Veterinary Medical Society 71, no. 1 (2020): 2005. http://dx.doi.org/10.12681/jhvms.22948.

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In this study, we aimed to compare the protective effects of melatonin and amifostine on radiation-induced oxidative stress. Fifty female Wistar rats (3-4 months old, weighing 200±25 g) were divided into five groups (with ten rats each) and treated as follows: control (Cont), radiotherapy alone (RT), radiotherapy + amifostine (RT+AMI), radiotherapy + melatonin (RT+MEL), radiotherapy + amifostine + melatonin (RT+AMI+MEL). Rats were irradiated individually with a single dose of 8 Gy and amifostine (200 mg/kg) and melatonin (10 mg/kg) was administered to rats 30 minutes before irradiation. At the

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Urrutia-Hernández, Thania Alejandra, Jorge Arturo Santos-López, Juana Benedí, et al. "Antioxidant and Hepatoprotective Effects of Croton hypoleucus Extract in an Induced-Necrosis Model in Rats." Molecules 24, no. 14 (2019): 2533. http://dx.doi.org/10.3390/molecules24142533.

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The aim of this study was to evaluate the antioxidant and hepatoprotective activity of Croton hypoleucus (EC). The present work reports the first pharmacological, toxicological, and antioxidant studies of EC extract on liver injury. Liver necrosis was induced by thioacetamide (TAA). Five groups were established: Croton Extract (EC), thioacetamide (TAA), Croton extract with thioacetamide (EC + TAA), vitamin E with thioacetamide (VE + TAA) and the positive control and vehicle (CT). For EC and EC + TAA, Wistar rats (n = 8) were intragastrically pre-administered for 4 days with EC (300 mg/kg.day)

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Barto, Tara L., Clarissa F. Morency, Nicoline Schaap, Ami B. Patel, and Daniel J. Monticello. "Intestinal Absorption of Lipids Using a Pancreatic Enzyme-Free Nutritional Supplement in Patients with Cystic Fibrosis: A Randomized, Double-Blind, Crossover Pilot Trial." Nutrients 14, no. 3 (2022): 680. http://dx.doi.org/10.3390/nu14030680.

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Nutritional supplements for patients with exocrine pancreatic insufficiency (EPI) typically utilize pancreatic enzyme replacement therapy (PERT) which is associated with gastrointestinal side effects. We evaluated serum triglyceride levels in patients with cystic fibrosis following consumption of an enzyme-modified oil oral nutritional supplement (EMO-ONS) versus a standard triacylglycerol-based ONS product (TAG-ONS) used concomitantly with PERT and patient tolerability between the two approaches. Ten subjects with CF and EPI taking PERT were enrolled in a single-center, double-blind, cross-ov

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Huang, Kun-Long, Ching-Chang Tsai, Hung-Chun Fu, et al. "Prophylactic Transcatheter Arterial Embolization Helps Intraoperative Hemorrhagic Control for REMOVING Invasive Placenta." Journal of Clinical Medicine 7, no. 11 (2018): 460. http://dx.doi.org/10.3390/jcm7110460.

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Objectives: The purpose of this article is to investigate the estimated blood loss in pregnant women undergoing cesarean section and placental extirpation to treat abnormal placentation and compare the outcomes of those who underwent prophylactic transcatheter arterial embolization (TAE) with those who did not. Methods: A retrospective study was conducted on 17 pregnant women diagnosed with abnormal placentation in 2001–2018 in a single tertiary center. The patients were diagnosed by surgical finding, ultrasound, or magnetic resonance imaging (MRI). These patients were divided into two groups:

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Ghasemi, Farshad, Mobina Mohammadi, Fatemeh Ghaffari, Ali Hosseini-Sharifabad, Navid Omidifar, and Amir Nili-Ahmadabadi. "Therapeutic Potential of Pentoxifylline in Paraquat-Induced Pulmonary Toxicity: Role of the Phosphodiesterase Enzymes." Drug Research 74, no. 05 (2024): 241–49. http://dx.doi.org/10.1055/a-2314-1137.

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AbstractPentoxifylline (PTX), a non-selective phosphodiesterase inhibitor, has demonstrated protective effects against lung injury in animal models. Given the significance of pulmonary toxicity resulting from paraquat (PQ) exposure, the present investigation was designed to explore the impact of PTX on PQ-induced pulmonary oxidative impairment in male mice.Following preliminary studies, thirty-six mice were divided into six groups. Group 1 received normal saline, group 2 received a single dose of PQ (20 mg/kg; i.p.), and group 3 received PTX (100 mg/kg/day; i.p.). Additionally, treatment group

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Cakina, Suat, Samil Ozturk, and Latife Ceyda Irkin. "The Preventive Effect of N-Acetylcysteine on Liver Tissue Against Doxorubicin-Induced Oxidative Stress in Rats." Acta Natura et Scientia 5, no. 1 (2024): 11–18. https://doi.org/10.61326/actanatsci.v5i1.2.

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Doxorubicin (DOX) is a chemotherapeutic agent and is widely used in cancer treatment. There are some studies suggesting oxidative stress-induced toxic changes in the liver due to DOX administration. The aim of this study was to reveal the oxidative damage of DOX in liver tissue at molecular level and to evaluate the protective effect of N-acetyl cysteine (NAC) against DOX oxidative damage. Twenty four rats weighing 150-200 g were randomly divided into four equal groups; group 1: control, group 2: received a single dose of DOX, group 3: received NAC for 28 days and group 4: received a single do

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Richter, Felix. "A broad introduction to RNA-Seq." WikiJournal of Science 4, no. 1 (2021): 4. http://dx.doi.org/10.15347/wjs/2021.004.

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RNA-Seq, named as an abbreviation of "RNA sequencing" and sometimes spelled RNA-seq, RNAseq, or RNASeq, uses next-generation sequencing (NGS) to reveal the presence and quantity of ribonucleic acid (RNA) in a biological sample at a given moment.[1][2] RNA-Seq is used to analyze the continuously changing cellular transcriptome (Figure 1). Specifically, RNA-Seq facilitates the ability to look at alternative gene spliced transcripts, post-transcriptional modifications, gene fusion, mutations/single nucleotide polymorphisms (SNPs) and changes in gene expression over time, or differences in gene ex

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Rech Feldmann, Cristina, Jessica Nespolo Martins, Fabio Shiniti Mizutani, Danilo Lazzari Ciotti, Victoria Alberton, and Simone Beatriz Alberton. "EVALUATION OF VOLUMETRIC MAINTENANCE AFTER SINGLE AND MULTIPLE DENTAL EXTRACTION USING LAMINATED TITTANIUM SHEET -." Health and Society 2, no. 04 (2022): 187–202. http://dx.doi.org/10.51249/hs.v2i04.902.

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The post-extraction border preservation is a fundamental procedure to the maintenance of alveolar volume prioritizing an aesthetical and functional improvement in the im- plant’s positioning. This thesis’s objective was to evaluate the titanium membrane (Sur- gitime Titânio Seal® – Bionnovation, Brasil) covered post extraction alveolar bone di- mensional alterations, while comparing areas to unitary and multiple exodontias. 20 pre and post-operation tomographical exams were evaluated, from areas where unitary den- tal extractions (G1) and multiple dental extractions (G2) occurred. In every cas

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Silbernagel, Guenther, Juergen Machann, Susanne Unmuth, et al. "Effects of 4-week very-high-fructose/glucose diets on insulin sensitivity, visceral fat and intrahepatic lipids: an exploratory trial." British Journal of Nutrition 106, no. 1 (2011): 79–86. http://dx.doi.org/10.1017/s000711451000574x.

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An increasing amount of fructose in the diet is suggested to play a causal role in the pathogenesis of the metabolic syndrome, type 2 diabetes and fatty liver. Our aim was to investigate and compare the effects of very high fructose and very high glucose in hyperenergetic diets on glucose and lipid metabolism and on fat depots in healthy humans. We conducted an exploratory, prospective, randomised, single-blinded, intervention trial. Participants in addition to a balanced weight-maintaining diet received 150 g of fructose or glucose/d for 4 weeks. Insulin sensitivity was estimated from oral gl

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Mironenko, A. V. "Study of the Cumulative Properties of the Long-acting Preparation "Flyblock insecticidal tag." Russian Journal of Parasitology 14, no. 3 (2020): 99–103. http://dx.doi.org/10.31016/1998-8435-2020-14-3-99-103.

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The purpose of the research is to study the cumulative properties of the long-acting preparation "Flyblock insecticidal tag". Materials and methods. The cumulative properties of the "Flyblock insecticidal tag" preparation were studied by the subchronic toxicity method on 20 male guinea pigs, which were divided into experimental and control groups of 10 animals each. A solution for impregnating a polymer plate of the preparation "Flyblock insecticidal tag" was applied to the skin, on a previously trimmed area of the coat 4 × 4 cm in size in the spinal column using a disposable syringe for injec

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Díaz-Peña, Roberto, Ana M. Aransay, Beatriz Suárez-Álvarez, et al. "A high density SNP genotyping approach within the 19q13 chromosome region identifies an association of a CNOT3 polymorphism with ankylosing spondylitis." Annals of the Rheumatic Diseases 71, no. 5 (2012): 714–17. http://dx.doi.org/10.1136/annrheumdis-2011-200661.

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ObjectiveTo identify genomic variants in the 19q13 chromosome region associated with ankylosing spondylitis (AS) in human leucocyte antigen (HLA)-B27-positive populations.MethodsHigh-throughput genotyping of 1536 haplotype-tag single nucleotide polymorphisms (SNPs) was performed in 249 patients with AS and 302 healthy controls. Some of the identified associations were validated by genotyping four SNPs in two additional cohorts consisting of 412 cases/301 controls and 144 cases/203 controls. All individuals selected (both cases and controls) were HLA-B27-positive.ResultsTwo markers in two diffe

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Fuji, Shigeo, Takahiro Fukuda, Sung-Won Kim, et al. "Low-Dose ATG-F Reduces Non-Relapse Mortality after Reduced-Intensity Bone Marrow Transplantation from an Unrelated Donor: A Single-Center Analysis of 65 Patients." Blood 110, no. 11 (2007): 5070. http://dx.doi.org/10.1182/blood.v110.11.5070.5070.

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Abstract Background: In Japan, peripheral blood stem cell transplantation from an unrelated donor has not been approved. Therefore, for unrelated bone marrow transplantation with a reduced-intensity conditioning regimen (u-RIST), low-dose TBI has been added to facilitate engraftment. However, non-relapse mortality (NRM), which was mostly related to GVHD, was extremely high (54% at 1 year) after u-RIST with cladribine/busulfan/TBI 4 Gy (Kim et al. ASH 2006). To overcome this problem, we introduced antithymocyte globulin (Fresenius: ATG-F) at a lower dosage of 5–10 mg/kg to replace TBI. This stu

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López-Helguera, I., P. Whittaker, A. Behrouzi, and M. G. Colazo. "12 INITIAL GONADOTROPIN-RELEASING HORMONE TREATMENT INCREASED PREGNANCY PER TIMED INSEMINATION ONLY IN ACYCLIC BEEF HEIFERS SUBJECTED TO A 5-DAY CO-SYNCH PROTOCOL." Reproduction, Fertility and Development 28, no. 2 (2016): 135. http://dx.doi.org/10.1071/rdv28n2ab12.

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We have shown that inclusion of initial gonadotropin-releasing hormone (GnRH) in a 5-day Co-synch protocol is unnecessary to achieve acceptable pregnancy rates in dairy heifers (2011 Theriogenology 76, 578). This study determined the efficacy of a modified (without initial GnRH) 5-day Co-synch protocol for timed AI (TAI) and the effect of interval from progesterone device removal to TAI on pregnancy per TAI (P/TAI) in acyclic and cyclic beef heifers. Heifers (n = 1062; 302 to 515 kg of body weight, and 13 to 15 months of age) at 2 locations were assigned to either a 5-day Co-synch protocol wit

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Jones, Michael K., Andrew Kent, Kellen Gil, et al. "Outcomes of Haplo-Cord and Dual-Cord Transplants: A Single-Center Retrospective Analysis." Blood 142, Supplement 1 (2023): 7084. http://dx.doi.org/10.1182/blood-2023-190558.

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Background: Despite the concurrent use of tandem haploidentical-umbilical cord (haplo-cord) and dual-umbilical cord (dual-cord) allogeneic hematopoietic stem cell transplant (HSCT) approaches for over a decade, there have been few comparisons of their outcomes (van Besien et al. Hematologica, 2016). No previous studies have evaluated differences following identical conditioning regimens. We report a retrospective analysis comparing patients treated with haplo-cord or dual-cord HSCTs at our institution following the same conditioning regimen. Methods: Between 10/2012-10/2022, 70 haplo-cord and

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Rosenfeld, Warren N., Jonathan M. Davis, Lance Parton, et al. "Safety and Pharmacokinetics of Recombinant Human Superoxide Dismutase Administered Intratracheally to Premature Neonates With Respiratory Distress Syndrome." Pediatrics 97, no. 6 (1996): 811–17. http://dx.doi.org/10.1542/peds.97.6.811.

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Objective. As a first step in the evaluation of recombinant human CuZn superoxide dismutase (rhSOD) in the prevention of neonatal lung injury, safety and pharmacokinetics of intratracheally (IT) administered rhSOD were studied. Methods. Twenty-six preterm infants weighing 750 to 1250 g with respiratory distress syndrome were studied in three sequential groups (placebo, 0.5, and 5 mg/kg). Placebo or rhSOD was administered IT 30 minutes after the first surfactant dose. Serial blood and urine studies, rhSOD levels, tracheal aspirate fluid (TAF) markers of acute inflammation, radiographs, and ultr

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Khamdiyah Indah K. "ANALYSIS OF ANTIHYPERTENSION THERAPY IN HYPERTENSION BPJS PATIENTS IN PURBALINGGA DISTRICT." Jurnal Cakrawala Ilmiah 2, no. 4 (2022): 1283–300. http://dx.doi.org/10.53625/jcijurnalcakrawalailmiah.v2i4.4315.

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Hypertension is a problem in the world because hypertension is one of the entry points for other disease risk factors. According to basic health research data (Rikesdar, 2018) the incidence of hypertension cases is 34.1%. According to the Purbalingga Health Office, the number of cases of hypertension in 2017 was 1,252 cases (14.26%) of 144,633 people aged 18 who had high blood pressure measured at the puskesmas and its network. Each antihypertensive drug will always show a different effect on blood pressure patient. This research was conducted to find out the therapeutic profile of single and

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Pejcic, Ivica, Svetislav Vrbic, Sladjana Filipovic, et al. "The effect of combined chemotherapy with or without potentiation with interferon alpha or tamoxifen for melanoma." Archive of Oncology 12, no. 1 (2004): 25–28. http://dx.doi.org/10.2298/aoo0401025p.

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BACKGROUND: Metastatic melanoma has shown only limited responsiveness to chemotherapy or immunotherapy. The most commonly used single-agent chemotherapy comes from the nitrosourea group of agents and provides response rates of less than 20%. Several cytotoxic agents have been combined with no dramatic benefit. The incorporation of tamoxifen or interferon in chemotherapy regimens has proven effective in some trials. METHODS: From July 1998 to March 2002, 45 patients with metastatic melanoma were enrolled for the study. None of the patients had previously received chemotherapy. The aim of the st

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Takagi, Shinsuke, Mitsuhiro Yuasa, Naoyuki Uchida, et al. "Cord Blood Units Containing Lower CD34+ Cells (0.5 - 1.0 x 105 /kg) Could be Alternative Donor Candidates for Single-Unit Cord Blood Transplantation for Adults: A Retrospective Study of 421 Patients in a Single Institute." Blood 132, Supplement 1 (2018): 2089. http://dx.doi.org/10.1182/blood-2018-99-119827.

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Abstract BACKGROUND: Cord blood is an established alternative donor cell source for allogeneic hematopoietic cell transplantation. However, engraftment failure is still a major concern after transplantation, especially for patients transplanted lower doses of donor cells. Higher CD34+ cell dose leads to a secure and fast engraftment, and the units of cord blood which contain CD34+ cells of 1.0 - 1.7 x 105 /kg at freezing or 1.0 - 1.2 x 105 /kg at thawing are recommended (Thomas' Hematopoietic Cell Transplantation, 5th Edition). Actually, most adult patients cannot obtain such sufficient cell d

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