Academic literature on the topic 'Singola molecola'

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Journal articles on the topic "Singola molecola"

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Pancani, Roberta, Alessandra Pagano, Marta Lomi, Elisabetta Casto, Sara Cappelli, and Alessandro Celi. "Farmaci antitumorali e tromboembolismo venoso." Cardiologia Ambulatoriale 31, no. 2 (2023): 139–48. http://dx.doi.org/10.17473/1971-6818-2023-2-6.

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Studi di popolazione hanno evidenziato un incremento dell’incidenza di tromboembolismo venoso (TEV) nei pazienti neoplastici in corso di trattamento con farmaci antitumorali. Sono state condotte ricerche cliniche allo scopo di chiarire il possibile ruolo di singoli agenti antitumorali nella modulazione del rischio di TEV, riscontrando fra essi alcune differenze. Gli studi disponibili presentano diversi limiti: non consentono un confronto diretto tra molecole poiché gli schemi di trattamento si basano generalmente su combinazioni di farmaci e spesso per ricavare dati su una singola molecola è n
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Marcucci, Guido, Drew Watson, Shweta Kapoor, et al. "Superior therapy response predictions for patients with acute myeloid leukemia (AML) using Cellworks Singula: MyCare-009-01." Journal of Clinical Oncology 38, no. 15_suppl (2020): e19502-e19502. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e19502.

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e19502 Background: Despite using cytogenetic and molecular-risk stratification and precision medicine, the current overall outcome of AML patients remains relatively poor. Therapy selection is often based on information considering only cytogenetics and single molecular aberrations and ignoring other patient-specific omics data that could potentially enable more effective treatments. The Cellworks Singula™ report predicts response for physician prescribed therapies (PPT) using the novel Cellworks Omics Biology Model (CBM) to simulate downstream molecular effects of cell signaling, drugs, and r
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Stein, Anthony Selwyn, Drew Watson, Shweta Kapoor, et al. "Superior therapy response predictions for patients with myelodysplastic syndrome (MDS) using Cellworks Singula: MyCare-009-02." Journal of Clinical Oncology 38, no. 15_suppl (2020): e19528-e19528. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e19528.

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e19528 Background: Despite using cytogenetic and molecular-risk stratification and precision medicine, the current overall outcome of MDS patients remains relatively poor. Therapy selection is often based on information considering only cytogenetics and single molecular aberrations and ignoring other patient-specific omics data that could potentially enable more effective treatments. The Cellworks Singula™ report predicts response for physician prescribed therapies (PPT) using the novel Cellworks Omics Biology Model (CBM) to simulate downstream molecular effects of cell signaling, drugs, and r
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Wen, Patrick Y., Drew Watson, Shweta Kapoor, et al. "Superior therapy response predictions for patients with glioblastoma (GBM) using Cellworks Singula: MyCare-009-03." Journal of Clinical Oncology 38, no. 15_suppl (2020): 2519. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.2519.

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2519 Background: Despite using cytogenetic and molecular-risk stratification and precision medicine, the current overall outcome of GBM patients remains relatively poor. Therapy selection is often based on information considering only a single aberration and ignoring other patient-specific omics data which could potentially enable more effective treatment selection. The Cellworks Singula™ report predicts response for physician prescribed therapies (PPT) using the novel Cellworks Omics Biology Model (CBM) to simulate downstream molecular effects of cell signaling, drugs, and radiation on patien
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Ahluwalia, Manmeet Singh, Drew Watson, Shweta Kapoor, et al. "Superior therapy response predictions for patients with low-grade glioma (LGG) using Cellworks Singula: MyCare-009-04." Journal of Clinical Oncology 38, no. 15_suppl (2020): 2569. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.2569.

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2569 Background: Despite using cytogenetic and molecular-risk stratification and precision medicine, the current overall outcome of LGG patients remains relatively poor. Therapy selection is often based on information considering only a single aberration and ignoring other patient-specific omics data which could potentially enable more effective treatments. The Cellworks Singula report predicts response for physician prescribed therapies (PPT) using the novel Cellworks Omics Biology Model (CBM) to simulate downstream molecular effects of cell signaling, drugs, and radiation on patient-specific
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Marcucci, Guido, Drew Watson, Prashant Ramachandran Nair, et al. "Assessment of Cellworks Omics Biosimulation Therapy Response Predictions for Patients with Acute Myeloid Leukemia (AML) Using Cellworks Singula™: Mycare-020-01." Blood 136, Supplement 1 (2020): 35. http://dx.doi.org/10.1182/blood-2020-142184.

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Background. In addition to clinical considerations (e.g., age, de novo vs secondary disease, comorbidities), therapy selection for AML patients is often based on information considering only cytogenetics and/or molecular aberrations and ignoring other patient-specific omics information that could potentially enable selection of more effective treatments. In turn, despite using cytogenetic and molecular-risk stratification, the current overall outcome of AML patients remains relatively poor. The Cellworks Singula™ report predicts clinical response to physician-prescribed treatments using the no
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Stein, Anthony S., Drew Watson, Prashant Ramachandran Nair, et al. "Superior Therapy Response Predictions for Patients with Myelodysplastic Syndrome (MDS) Using Cellworks Singula™: Mycare-020-02." Blood 136, Supplement 1 (2020): 9–10. http://dx.doi.org/10.1182/blood-2020-142214.

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Background: Therapy selection for MDS patients is often based on information considering only cytogenetics and single molecular aberrations and ignoring other patient-specific omics data that could potentially enable more effective treatments. In turn, despite using cytogenetic and molecular-risk stratification and precision medicine, the current overall outcome of MDS patients remains relatively poor. The Cellworks Singula™ report predicts response for physician prescribed treatments using the novel Cellworks Omics Biology Model (CBM) to simulate downstream molecular effects of cell signaling
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Velcheti, Vamsidhar, Michael Castro, Drew Watson, et al. "Superior overall survival (OS), progression-free survival (PFS), and clinical response (CR) predictions for patients with non-small cell lung cancer (NSCLC) using Cellworks Singula: myCare-022-05." Journal of Clinical Oncology 39, no. 15_suppl (2021): 9117. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.9117.

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9117 Background: The Cellworks Singula Therapeutic Response Index (TRI) has been developed to assist clinicians and NSCLC patients in choosing between competing therapeutic options. In contrast to approaches that consider single aberrations, which often yield limited benefit, Cellworks utilizes an individual patient’s next generation sequencing results and a mechanistic multi-omics biology model, the Cellworks Omics Biology Model (CBM), to biosimulate downstream molecular effects of cell signaling, drugs, and radiation on patient-specific in silico diseased cells. For any individual patient an
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Wen, Patrick Y., Michael Castro, Drew Watson, et al. "Superior overall survival (OS) and disease-free survival (DFS) predictions for patients with glioblastoma multiforme (GBM) using Cellworks Singula: myCare-022-03." Journal of Clinical Oncology 39, no. 15_suppl (2021): 2017. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.2017.

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2017 Background: The Cellworks Singula Therapeutic Response Index (TRI) has been developed to assist clinicians and GBM patients in choosing between competing therapeutic options. In contrast to approaches that consider single aberrations, which often yield limited benefit, Cellworks utilizes an individual patient’s next generation sequencing results and a mechanistic multi-omics biology model, the Cellworks Omics Biology Model (CBM), to biosimulate downstream molecular effects of cell signaling, drugs, and radiation on patient-specific in silico diseased cells. For any individual patient and
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Goglia, U. "Incretins in healthy and type 2 diabetic people." Journal of AMD 27, no. 2 (2024): 96. http://dx.doi.org/10.36171/jamd24.27.2.3.

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Nell’ultima decade abbiamo osservato sempre maggiormente la diffusione e l’utilizzo di farmaci analoghi recettoriali degli ormoni incretinici nella gestione e nel trattamento di soggetti con diabete mellito tipo 2 ed affetti da obesità. Infatti dalla pubblicazione sul New England Journal of Medicine dello studio Leader nel 2016, che valutava gli effetti cardiovascolari della liraglutide, numerose ulteriori evidenze hanno confermato i benefici clinici degli analoghi recettoriali singoli e doppi di tali ormoni. Ma quale è il ruolo specifico di tali molecole (Glucagon-like Peptide-1 [GLP-1] e Glu
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Dissertations / Theses on the topic "Singola molecola"

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CHOUDHARY, DHAWAL. "Studio a livello di singola molecola del folding, misfolding e aggregazione di proteine e dell’attività chaperonica della HSPB8." Doctoral thesis, Università degli studi di Modena e Reggio Emilia, 2020. http://hdl.handle.net/11380/1199862.

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Negli ultimi decenni le pinze ottiche si sono rivelate una tecnica sperimentale estremamente efficace per eseguire studi di spettroscopia di forza a livello di singola molecola. In particolare, un’applicazione delle pinze ottiche che sta avendo una rilevanza biomedica sempre più importante è quella relativa allo studio dei processi di ripiegamento corretto (folding), non corretto (misfolding) e dell’aggregazione di proteine. Di forte rilevanza biomedica è anche la possibilità offerta dalle pinze ottiche di caratterizzare in grande dettaglio i meccanismi molecolari che mediano le interazioni tr
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BUGLIONE, ENRICO. "Nanomeccanica per la Ricerca sul Cancro." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/304787.

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Nonostante gli enormi passi avanti sulla comprensione dei meccanismi d’azione del cancro e nello sviluppo di farmaci antitumorali, la maggior parte delle forme di cancro è ancora incurabile. La ragione di tale insuccesso è radicata nella complessità di questa malattia, che è ancora poco conosciuta sia in fase di insorgenza, dovuta alla misregolazione di oncogeni, sia in fase di metastatizzazione delle cellule cancerose. Lo studio di tali caratteristiche da un punto di vista meccanico può fornire una visione differente dei meccanismi di azione del cancro ed aiutare a contestualizzarli all’inter
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CORTI, ROBERTA. "Single molecule force spectroscopy of proteins and DNA." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/273770.

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Negli ultimi decenni, lo sviluppo di nuove tecniche di singola molecola ha creato le basi per nuovi paradigmi nel campo della biofisica. In particolare, la nanomanipolazione di singole biomacromolecole ha permesso la caratterizzazione meccanica di proteine e DNA, cercando di evidenziare la relazione fondamentale tra struttura e funzione biologica. Nel corso degli anni sono stati sviluppati diversi metodi di nanomanipolazione: tra questi, il Microscopio a Forza Atomica (AFM), il Magnetic Tweezers (MT) e il Flow-Stretching (F-S) accoppiato a fluorescenza. Queste tre tecniche sono state utilizza
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Murello, Anna. "La spettroscopia di forza basata sull'AFM nello studio dello spazio conformazionale e dei processi aggregativi di proteine prioniche." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8878/.

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Le malattie neurodegenerative sono caratterizzate da aggregazione proteica, dipendente dalla perdita della usuale struttura fisiologica funzionale delle proteine coinvolte, a favore di conformazioni tossiche (patologiche). Il modello corrente descrive questi cambiamenti conformazionali come eventi rari e ritiene che non esista una sola conformazione patogena, ma che tali possibili conformazioni siano piuttosto eterogenee. La caratterizzazione di queste strutture è, di conseguenza, difficile con le tradizionali tecniche in bulk che permettono di studiare solo la conformazione media e non rendo
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Rajagopal, Senthil Arun. "SINGLE MOLECULE ELECTRONICS AND NANOFABRICATION OF MOLECULAR ELECTRONIC DEVICES." Miami University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=miami1155330219.

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Sikor, Martin. "Single-molecule fluorescence studies of Protein Folding and Molecular Chaperones." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-138521.

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Ökten, Zeynep. "Single molecule mechanics and the myosin family of molecular motors." [S.l.] : [s.n.], 2006. http://www.diss.fu-berlin.de/2006/6/index.html.

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Zhao, Xiaotao. "The synthesis and single-molecule conductance of conjugated molecular wires." Thesis, Durham University, 2014. http://etheses.dur.ac.uk/10634/.

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The past decades have seen the fast development of electronic devices in the industrial sector. There is increasingly rapid growth in the demand for alternative electronic building blocks to compliment, and possibly replace, the conventional silicon-based products. Electronic devices based on organic molecules, especially those based on single molecules, receive intense studies both theoretically and experimentally. In this presented work, a new family of oligo(aryleneethenylene)s (OAE)s with molecular lengths (N…N distance) of ca. 2-6 nm were designed to investigate the length dependence of c
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Lange, Jeffrey J. "Studies of molecular motions by fluorescence microscopy at single molecule and single fiber levels." Diss., Manhattan, Kan. : Kansas State University, 2009. http://hdl.handle.net/2097/1629.

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Rüttinger, Steffen. "Confocal microscopy and quantitative single molecule techniques for metrology in molecular medicine." [S.l.] : [s.n.], 2006. http://opus.kobv.de/tuberlin/volltexte/2007/1434.

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Books on the topic "Singola molecola"

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Dinman, Jonathan D. Biophysical approaches to translational control of gene expression. Springer New York, 2013.

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Kaila, M. M. Molecular Imaging of the Brain: Using Multi-Quantum Coherence and Diagnostics of Brain Disorders. Springer Berlin Heidelberg, 2013.

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Wernsdorfer, W. Molecular nanomagnets. Edited by A. V. Narlikar and Y. Y. Fu. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533060.013.4.

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This article describes the quantum phenomena observed in molecular nanomagnets. Molecular nanomagnets, or single-molecule magnets (SMMs), provides a fundamental link between spintronics and molecular electronics. SMMs combine the classic macroscale properties of a magnet with the quantum properties of a nanoscale entity. The resulting field, molecular spintronics, aims at manipulating spins and charges in electronic devices containing one or more molecules. This article first considers molecular nanomagnets and the giant spin model for nanomagnets before discussing the quantum dynamics of a di
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Launay, Jean-Pierre, and Michel Verdaguer. The localized electron: magnetic properties. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198814597.003.0002.

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After preliminaries about electron properties, and definitions in magnetism, one treats the magnetism of mononuclear complexes, in particular spin cross-over, showing the role of cooperativity and the sensitivity to external perturbations. Orbital interactions and exchange interaction are explained in binuclear model systems, using orbital overlap and orthogonality concepts to explain antiferromagnetic or ferromagnetic coupling. The phenomenologically useful Spin Hamiltonian is defined. The concepts are then applied to extended molecular magnetic systems, leading to molecular magnetic material
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(Editor), John E. Gilbert, Y. S. Han (Editor), J. A. Hogan (Editor), Joseph D. Lakey (Editor), D. Weiland (Editor), and G. Weiss (Editor), eds. Smooth Molecular Decompositions of Functions and Singular Integral Operators. American Mathematical Society, 2002.

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Orrit, Michel. Single-molecule spectroscopy. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198768609.003.0006.

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This chapter gives an overview of the main optical methods used to detect and study single molecules and other small objects (nano-objects). Much of the work so far has exploited the excellent sensitivity and selectivity of fluorescence, but several new techniques, mostly based on nonlinear optics, have recently reached the single-molecule or single-nanoparticle regime. The chapter briefly discusses some results with reference to published reviews. Single-molecule techniques have now been incorporated into the arsenal of the physico-chemist and the cell biologist. However, the recent developme
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Appasani, Krishnarao, and Raghu Kiran Appasani, eds. Single-Molecule Science. Cambridge University Press, 2022. http://dx.doi.org/10.1017/9781108525909.

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Single Molecule Science (SMS) has emerged from developing, using and combining technologies such as super-resolution microscopy, atomic force microscopy, and optical and magnetic tweezers, alongside sophisticated computational and modelling techniques. This comprehensive, edited volume brings together authoritative overviews of these methods from a biological perspective, and highlights how they can be used to observe and track individual molecules and monitor molecular interactions in living cells. Pioneers in this fast-moving field cover topics such as single molecule optical maps, nanomachi
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Launay, Jean-Pierre, and Michel Verdaguer. Electrons in Molecules. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198814597.001.0001.

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The book treats in a unified way electronic properties of molecules (magnetic, electrical, photophysical), culminating with the mastering of electrons, i.e. molecular electronics and spintronics and molecular machines. Chapter 1 recalls basic concepts. Chapter 2 describes the magnetic properties due to localized electrons. This includes phenomena such as spin cross-over, exchange interaction from dihydrogen to extended molecular magnetic systems, and magnetic anisotropy with single-molecule magnets. Chapter 3 is devoted to the electrical properties due to moving electrons. One considers first
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Divan, Aysha, and Janice A. Royds. 5. Molecular interactions. Oxford University Press, 2016. http://dx.doi.org/10.1093/actrade/9780198723882.003.0005.

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Every nucleated diploid cell in the body, with the exception of B and T cells of the immune system, has the same genome as its originating single fertilized egg. During development, this single cell differentiates into a complex multicellular organism composed of various cells and tissues each carrying out specialized functions. Although each cell contains a genome of data it needs to select the relevant information from this genetic blueprint to fulfil its own specific function. ‘Molecular interactions’ shows that proteins must be produced in the right place and at the right time. This requir
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van Ruitenbeek, Jan M. Quasi-ballistic electron transport in atomic wires. Edited by A. V. Narlikar and Y. Y. Fu. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533046.013.5.

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This article describes quasi-ballistic electron transport in atomic wires. It begins with a review of experiments on the conduction properties for single metal atoms. Nearly all the information on the properties of such nanocontacts should be extracted from the current and voltage only. Nevertheless, a wide range of techniques has been developed to obtain detailed information. The article proceeds by considering various experimental techniques for characterizing single-atom contacts, along with their application for the study of conducting chains of individual metal atoms and for metal–molecul
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Book chapters on the topic "Singola molecola"

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Loseva, Elizaveta, Jaap van Krugten, Aniruddha Mitra, and Erwin J. G. Peterman. "Single-Molecule Fluorescence Microscopy in Sensory Cilia of Living Caenorhabditis elegans." In Single Molecule Analysis. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3377-9_7.

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AbstractIntracellular transport of organelles and biomolecules is vital for several cellular processes. Single-molecule fluorescence microscopy can illuminate molecular aspects of the dynamics of individual biomolecules that remain unresolved in ensemble experiments. For example, studying single-molecule trajectories of moving biomolecules can reveal motility properties such as velocity, diffusivity, location and duration of pauses, etc. We use single-molecule imaging to study the dynamics of microtubule-based motor proteins and their cargo in the primary cilia of living C. elegans. To this end, we employ standard fluorescent proteins, an epi-illuminated, widefield fluorescence microscope, and primarily open-source software. This chapter describes the setup we use, the preparation of samples, a protocol for single-molecule imaging in primary cilia of C. elegans, and data analysis.
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Pilizota, Teuta, Yoshiyuki Sowa, and Richard M. Berry. "Single-Molecule Studies of Rotary Molecular Motors." In Handbook of Single-Molecule Biophysics. Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-76497-9_7.

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Hornung, Tassilo, James Martin, David Spetzler, Robert Ishmukhametov, and Wayne D. Frasch. "Microsecond Resolution of Single-Molecule Rotation Catalyzed by Molecular Motors." In Single Molecule Enzymology. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-261-8_18.

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Dulin, David. "An Introduction to Magnetic Tweezers." In Single Molecule Analysis. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3377-9_18.

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AbstractMagnetic tweezers are a single-molecule force and torque spectroscopy technique that enable the mechanical interrogation in vitro of biomolecules, such as nucleic acids and proteins. They use a magnetic field originating from either permanent magnets or electromagnets to attract a magnetic particle, thus stretching the tethering biomolecule. They nicely complement other force spectroscopy techniques such as optical tweezers and atomic force microscopy (AFM) as they operate as a very stable force clamp, enabling long-duration experiments over a very broad range of forces spanning from 10 fN to 1 nN, with 1–10 milliseconds time and sub-nanometer spatial resolution. Their simplicity, robustness, and versatility have made magnetic tweezers a key technique within the field of single-molecule biophysics, being broadly applied to study the mechanical properties of, e.g., nucleic acids, genome processing molecular motors, protein folding, and nucleoprotein filaments. Furthermore, magnetic tweezers allow for high-throughput single-molecule measurements by tracking hundreds of biomolecules simultaneously both in real-time and at high spatiotemporal resolution. Magnetic tweezers naturally combine with surface-based fluorescence spectroscopy techniques, such as total internal reflection fluorescence microscopy, enabling correlative fluorescence and force/torque spectroscopy on biomolecules. This chapter presents an introduction to magnetic tweezers including a description of the hardware, the theory behind force calibration, its spatiotemporal resolution, combining it with other techniques, and a (non-exhaustive) overview of biological applications.
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Duwez, Anne-Sophie. "Single-Molecule Measurements of Synthetic Molecular Machines at Work." In Single Molecular Machines and Motors. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-13872-5_1.

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Ganzhorn, Marc, and Wolfgang Wernsdorfer. "Molecular Quantum Spintronics Using Single-Molecule Magnets." In NanoScience and Technology. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-40609-6_13.

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Taran, Gheorghe, Edgar Bonet, and Wolfgang Wernsdorfer. "Single-Molecule Magnets and Molecular Quantum Spintronics." In Handbook of Magnetism and Magnetic Materials. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63210-6_18.

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McCauley, Micah J., Joha Joshi, Nicole Becker, et al. "Quantifying ATP-Independent Nucleosome Chaperone Activity with Single-Molecule Methods." In Single Molecule Analysis. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3377-9_2.

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AbstractThe dynamics of histone-DNA interactions govern chromosome organization and regulates the processes of transcription, replication, and repair. Accurate measurements of the energies and the kinetics of DNA binding to component histones of the nucleosome under a variety of conditions are essential to understand these processes at the molecular level. To accomplish this, we employ three specific single-molecule techniques: force disruption (FD) with optical tweezers, confocal imaging (CI) in a combined fluorescence plus optical trap, and survival probability (SP) measurements of disrupted and reformed nucleosomes. Short arrays of positioned nucleosomes serve as a template for study, facilitating rapid quantification of kinetic parameters. These arrays are then exposed to FACT (FAcilitates Chromatin Transcription), a non-ATP-driven heterodimeric nuclear chaperone known to both disrupt and tether histones during transcription. FACT binding drives off the outer wrap of DNA and destabilizes the histone-DNA interactions of the inner wrap as well. This reorganization is driven by two key domains with distinct function. FD experiments show the SPT16 MD domain stabilizes DNA-histone contacts, while the HMGB box of SSRP1 binds DNA, destabilizing the nucleosome. Surprisingly, CI experiments do not show tethering of disrupted histones, but increased rates of histone release from the DNA. SI experiments resolve this, showing that the two active domains of FACT combine to chaperone nucleosome reassembly after the timely release of force. These combinations of single-molecule approaches show FACT is a true nucleosome catalyst, lowering the barrier to both disruption and reformation.
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Xie, X. S., and H. P. Lu. "Single-Molecule Enzymology." In Single Molecule Spectroscopy. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56544-1_13.

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Dovichi, N. J., R. Polakowski, A. Skelley, D. B. Craig, and J. Wong. "Single-Molecule Enzymology." In Single Molecule Spectroscopy. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56544-1_14.

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Conference papers on the topic "Singola molecola"

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Armani, Andrea M., Yasaman Moradi, Marko Lilic, and Luciana Custer. "Nonlinear organic small molecule imaging agents." In Single Molecule Spectroscopy and Superresolution Imaging XVIII, edited by Rainer Erdmann, Felix Koberling, and Mike Heilemann. SPIE, 2025. https://doi.org/10.1117/12.3049087.

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Yeo, Wei-Hong, Yang Zhang, Junghun Kweon, Cheng Sun, and Hao F. Zhang. "Single-molecule localization uncertainties induced by molecular labeling." In Single Molecule Spectroscopy and Superresolution Imaging XVII, edited by Ingo Gregor, Rainer Erdmann, and Felix Koberling. SPIE, 2024. http://dx.doi.org/10.1117/12.3001243.

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Vargas-Hernandez, Sofia, Tyler Nelson, Yuya Nakatani, et al. "Use of single molecule techniques to investigate molecular mechanisms behind memory formation (Conference Presentation)." In Single Molecule Spectroscopy and Superresolution Imaging XVI, edited by Ingo Gregor, Rainer Erdmann, and Felix Koberling. SPIE, 2023. http://dx.doi.org/10.1117/12.2650681.

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DREWSEN, M. "COLD MOLECULAR IONS: SINGLE MOLECULE STUDIES." In Proceedings of the XXI International Conference on Atomic Physics. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814273008_0031.

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Marchetti, Laura, Fulvio Bonsignore, Rosy Amodeo, et al. "Single molecule tracking and spectroscopy unveils molecular details in function and interactions of membrane receptors." In Single Molecule Spectroscopy and Superresolution Imaging XIV, edited by Ingo Gregor, Rainer Erdmann, and Felix Koberling. SPIE, 2021. http://dx.doi.org/10.1117/12.2578193.

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Hill, S. C., M. D. Barnes, W. B. Whitten, and J. M. Ramsey. "Modeling Fluorescence Collection from Single Molecules in Liquid Microspheres." In Laser Applications to Chemical and Environmental Analysis. Optica Publishing Group, 1996. http://dx.doi.org/10.1364/lacea.1996.lwd.7.

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Optimization of molecular detection efficiencies is of central importance in analytical applications involving single molecule detection.1 In addition to limitations imposed on the fraction of molecules which can be detected by the average signal-to-noise ratio, experimental factors such as excitation inhomogeneity and molecular diffusion conspire to further limit "molecular detectability." Recent single molecule detection experiments in microdroplets suggest that such experimental limitations can be significantly reduced primarily because the molecule cannot diffuse away from the excitation v
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Kamenetska, Maria. "Self-Assembled Organometallic Molecular Wires in Single Molecule Circuits." In 2021 IEEE 16th Nanotechnology Materials and Devices Conference (NMDC). IEEE, 2021. http://dx.doi.org/10.1109/nmdc50713.2021.9677552.

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Hall, Drew A., Nagaraj Ananthapad Manabhan, Chulmin Choi, et al. "A CMOS Molecular Electronics Chip for Single-Molecule Biosensing." In 2022 IEEE International Solid- State Circuits Conference (ISSCC). IEEE, 2022. http://dx.doi.org/10.1109/isscc42614.2022.9731770.

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Lermer, N., M. D. Barnes, C.-Y. Kung, W. B. Whitten, and J. M. Ramsey. "High-Speed Single Molecule Detection in Microdroplet Streams." In Laser Applications to Chemical and Environmental Analysis. Optica Publishing Group, 1996. http://dx.doi.org/10.1364/lacea.1996.lwb.7.

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The detection of individual fluorescent molecules in liquids has been of great interest in recent years. Various fluorescence-based techniques shown to provide single molecule sensitivities include confocal microscopy [1], flow cell techniques [2], and levitated microdroplets [3]. The application of the microdroplet technique to single molecule detection offers many advantages. First, fluoresence decay rates and total fluoresence yield have been shown to be enhanced in glycerol microdroplets [4]. Additionally, the droplet confines the single fluorophore to a small volume thereby removing diffi
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Yildiz, Ahmet. "Dissecting the Molecular Mechanism of Kinesin with Single Molecule Imaging." In Laser Science. OSA, 2009. http://dx.doi.org/10.1364/ls.2009.lsthf3.

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Reports on the topic "Singola molecola"

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Iancu, Violeta. Single Molecule Switches and Molecular Self-Assembly: Low Temperature STM Investigations and Manipulations. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/955626.

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Darrow, C., T. Huser, C. Campos, M. Yan, S. Lane, and R. Balhorn. Single Fluorescent Molecule Confocal Microscopy: A New Tool for Molecular Biology Research and Biosensor Development. Office of Scientific and Technical Information (OSTI), 2000. http://dx.doi.org/10.2172/792442.

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Jeans, C., M. Thelen, and A. Noy. Single Molecule Studies of Chromatin. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/877892.

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Lu, H. Peter. Single-Molecule Interfacial Electron Transfer. Office of Scientific and Technical Information (OSTI), 2017. http://dx.doi.org/10.2172/1410506.

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Ho, Wilson. Single-Molecule Interfacial Electron Transfer. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1419408.

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Castro, A., and E. B. Shera. Single-molecule electrophoresis. Final report. Office of Scientific and Technical Information (OSTI), 1996. http://dx.doi.org/10.2172/272560.

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Chen, Peng. Single-Molecule Visualization of Living Polymerization. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada606984.

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Michael Holman, Ling Zang, Ruchuan Liu, and David M. Adams. Single Molecule Spectroscopy of Electron Transfer. Office of Scientific and Technical Information (OSTI), 2009. http://dx.doi.org/10.2172/966129.

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Borzenets, Ivan. Magnetic Avalanche Detector using Single-Molecule Magnets. Office of Scientific and Technical Information (OSTI), 2025. https://doi.org/10.2172/2524002.

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Lee, Ji-Young. Single Molecule Screening of Disease DNA Without Amplification. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/897373.

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