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Dissertations / Theses on the topic 'Siwe Disease'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Wang, Tingrong. "Experimental acute tubulointerstitial disease caused by cimetidine." Virtual Press, 1993. http://liblink.bsu.edu/uhtbin/catkey/879842.

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Cimetidine is a histamine H2-receptor antagonist that is among the most widely prescribed drugs in the world. In addition to its inhibitory action on gastric acid secretion, a possible role in kidney tubulointerstitial disease has been suggested. Isolated reports have also suggested an association between cimetidine administration and acute interstitial nephritis. The present study examined the effect of cimetidine on renal function in the rat. The nine rats used in this study had normal renal function and urinalyses before treatment with cimetidine. The cimetidine treated rats then developed

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2

Lee, Anne Maureen. "Size at birth and neonatal fibrinogen." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327261.

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3

Seeger, Joost. "Ischaemic preconditioning in exercise and disease : one size fits all?" Thesis, Liverpool John Moores University, 2016. http://researchonline.ljmu.ac.uk/4550/.

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Ischaemia reperfusion injury (IR-injury) occurs when blood supply to a certain area of the body is blocked, and is subsequently followed by reperfusion. During the period of ischaemia, tissue is damaged as a result of lack of oxygen. Rapid reperfusion is mandatory, but unfortunately causes damage in addition to the damage induced by ischaemia alone. While a prolonged period of ischaemia is harmful to the bodily tissue, short periods of ischaemia interspersed with short bouts of reperfusion have protective effects. This mechanism is called ischaemic preconditioning (IPC). In this thesis, the im

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4

Kennedy, Allyson E. "Identification of size and shape changes in orofacial development and disease." VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4143.

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Among the most prevalent and devastating types of human birth defects are those affecting the mouth and face, such as orofacial clefts. Children with malformed orofacial structures undergo multiple surgeries throughout their lifetime and struggle with facial disfigurements, speech, hearing, and eating problems. Therefore, facilitating new research in cranio- and orofacial development is paramount to prevention and treatment of these types of birth defects in humans. Xenopus laevis has emerged as a new tool for dissecting the mechanisms governing facial development. Thus, molecular analyses acc

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5

Jumper, Natalie. "Application of a site-specific in situ approach to keloid disease research." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/application-of-a-sitespecific-in-situ-approach-to-keloid-disease-research(f0a9bcae-93f0-4335-8839-afa5747f40d6).html.

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Keloid disease (KD) is a cutaneous fibroproliferative tumour characterised by heterogeneity, locally aggressive invasion and therapeutic resistance. Clinical, histological and molecular differences between the keloid scar centre and margin as well as recent evidence of the importance of epithelial-mesenchymal interactions (EMI) in KD pathobiology contribute to the complexity and diversity of KD, which coupled with the lack of a validated animal model have hindered research and effective management. Despite significant progress in the field of KD research, reliance on conventional monolayer cel

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6

Huang, Yidi. "Comprehensive Computational Analysis of Disease-site Microbiome in Patients with Myeloid Malignancy." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1575466186675208.

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7

Zhao, Kun. "Mathematical Methods for Network Analysis, Proteomics and Disease Prevention." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/math_diss/6.

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This dissertation aims at analyzing complex problems arising in the context of dynamical networks, proteomics, and disease prevention. First, a new graph-based method for proving global stability of synchronization in directed dynamical networks is developed. This method utilizes stability and graph theories to clarify the interplay between individual oscillator dynamics and network topology. Secondly, a graph-theoretical algorithm is proposed to predict Ca2+-binding site in proteins. The new algorithm enables us to identify previously-unknown Ca2+-binding sites, and deepens our understanding

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8

Zeng, Ke Han. "Innovative cuboid method to attenuate noises from site-measured heart sound signals." Thesis, University of Macau, 2015. http://umaclib3.umac.mo/record=b3335275.

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9

Nilsson, Greger. "Cardiovascular Side Effects of Radiotherapy in Breast Cancer." Doctoral thesis, Uppsala universitet, Enheten för onkologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179811.

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The aim of the thesis was to study cardiovascular side effects of radiotherapy (RT) in breast cancer (BC). In a study base of 25,171 women with BC diagnosed 1970-2000, we found a statistically significant 12% increase of stroke, compared to the stroke incidence in the background population. A case-control study of 282 cases with BC followed by a stroke and 1:1 matched controls with BC but not stroke was performed. In women irradiated to internal mammary chain (IMC) and supraclavicular lymph nodes (SCL) vs. a pooled group of women not irradiated or irradiated to targets other than IMC and SCL,

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10

McLoughlin, David J. "Analysis of the ligand binding site of the human 5-HTâ†1â†A serotonin receptor." Thesis, University of Kent, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285980.

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11

Allen, John. "Measurement and analysis of multi-site photoplethysmographic pulse waveforms in health and arterial disease." Thesis, University of Newcastle Upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247830.

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12

Garcia, Cheslymar. "Assessment of Bacteriuria and Surgical Site Infections in Dogs with Cranial Cruciate Ligament Disease." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/90406.

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Objective: The aims of this prospective clinical cohort study were to determine the prevalence of asymptomatic bacteriuria in dogs with cranial cruciate ligament disease and to determine which clinical parameters and clinicopathologic data are associated with asymptomatic bacteriuria. Another aim was to determine the incidence of surgical site infections in dogs with and without asymptomatic bacteriuria. Results: In 156 dogs with cruciate ligament disease, the prevalence of asymptomatic bacteriuria was 7.1%. Furthermore, the prevalence was 12.4% in female dogs and 0% in male dogs. The most co

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13

Butnor, John Robert. "Influence of site factors and vascular conductivity on the development of procerum root disease." Thesis, This resource online, 1996. http://scholar.lib.vt.edu/theses/available/etd-11182008-063437/.

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14

Gonnelli, Adriano. "Novel LRRK2 substrates at the presynaptic site in vesicle recycling pathways in Parkinson's disease." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3426750.

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Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease (AD) affecting about 1-2% of the population over 65 years of age (Farrer, 2006). The pathological hallmarks of PD are the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the presence of intracellular proteinaceous inclusions called “Lewy bodies” (LB) in surviving neurons (Damier et al., 1999; Frank et al., 2007). The etiology of PD is unknown, with a complex relationship between environmental and genetic factors, and aging being a required factor. The majority o

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15

Phoku, Nkosinathi Terrence. "Cardiovascular risk factors among 15-20 years old rural subjects residing in Dikgale Demographic Surveillance Site (DDSS), Limpopo Province." Thesis, University of Limpopo (Turfloop Campus), 2013. http://hdl.handle.net/10386/1048.

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Thesis (M.Sc. (Chemical Pathology) --University of Limpopo, 2013<br>Cardiovascular diseases (CVDs) are among one of the well documented conditions and pose a significant health burden in the world as they areconsidered to be of adult onset. However, recent studies have shown that in developed countries CVD risk factors are becoming prevalent in young people which isof great concern. Therefore, the aim of this study was to determine if CVD risk factors are present in young subjects aged 15-20 years of age residing in a rural area of a developing country. Methods: Subjects aged between 15-20 ye

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16

Kervinen, M. (Marko). "Membranous core domain of Complex I and mitochondrial disease modeling." Doctoral thesis, University of Oulu, 2006. http://urn.fi/urn:isbn:9514281187.

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Abstract Human mitochondria contain a circular genome called mitochondrial DNA (mtDNA). It encodes subunits of the respiratory chain enzymes involved in energy conservation in oxidative phosphorylation and the necessary RNA needed for their expression. Errors in these genes have been shown to cause diseases, called mitochondrial diseases, which mainly affect tissues with high energy-demand, such as brain, heart, and skeletal muscle, or to lead to the production of harmful by-products in the form of reactive oxygen species (ROS) during cellular respiration. ROS damage lipids, proteins, and DNA,

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17

Cheung, Yin-bun. "Size at birth and postnatal growth and development, morbidity and mortality /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21796361.

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18

Lombaard, Ansie. "On the human side... of illness and research." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/50051.

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Thesis (DPhil)--Stellenbosch University, 2004.<br>ENGLISH ABSTRACT: This qualitative study comprised an in-depth investigation into the subjective - the explicitly human - experience of those suffering from Myalgic Encephalomyelitis (ME). I was, firstly, concerned with the nature and meaning of the social side of illness, that is, the sufferer's encounters with doctor, family member, friend and acquaintance alike. I was, secondly, set to develop greater insight into the essentially personal experience of being ill. I was able to conclude that, even amidst the inhumane presence of utter ig

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19

Beiersdorfer, Alex. "Site-specific Regulation of Myosin Binding Protein-C." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1511856330493573.

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20

Palmer, Benjamin L. "Effect of welder group size on individual respiratory exposures to welding fumes." Oklahoma City : [s.n.], 2010.

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21

Spotswood, Timothy C. "Echocardiographic changes of left ventricular size and function in a canine normovolaemic anaemia model." Diss., University of Pretoria, 2006. http://hdl.handle.net/2263/23732.

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The objective of this study was to non-invasively document the changes in echocardiographic variables of left ventricular size and function during acute normovolaemic anaemia. This model was developed as a pilot study with the purpose of providing baseline information to investigate the pathophysiology, and more specifically the effect on the heart, of canine babesiosis-induced anaemia. The study group comprised of 11 mature healthy Beagle dogs that weighed between 9 and 15 kg. Severe normovolaemic anaemia was induced over a 3-4 day period by serial bleeding while maintaining normovolaemia by

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22

Andersson, Anne. "Long-term side effects after treatment of Hodgkin's lymphoma." Doctoral thesis, Umeå universitet, Onkologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-43287.

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Background Long-term side effects associated with the treatment of Hodgkin’s lymphoma (HL) have frequently been reported during the last decades. Studies have shown increased mortality in HL survivors. Following Hodgkin’s lymphoma, second malignancies (SM) and cardiovascular disease (CVD) are the most common causes of death in individuals treated for HL. This study investigates the incidence of side effects such as SM, CVD and infections in a cohort diagnosed with HL in Sweden between 1965 and 1995. In addition, this study identifies covariate risk factors for late side effects in order to dev

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23

Dixon, Justin Alexander. "Disease, morality and bioethics : an ethnographic study of a TB vaccine trial site in South Africa." Thesis, Durham University, 2017. http://etheses.dur.ac.uk/12266/.

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This thesis offers an ethnographic account of the work of a research institute called the South African Tuberculosis Vaccines Initiative (SATVI), which has been running tuberculosis (TB) vaccine trials in the Western Cape since 2001. The chapters show that SATVI has become deeply embedded in the local socioeconomic and healthcare landscape through the ground-level conduct of its vaccine trials. However, the significance of the trials in people’s lives goes beyond providing access to resources against the backdrop of withdrawing state structures. The focus is on how the trials have become entan

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24

Jones, Ann Elizabeth. "Hippocampal and entohrinal cortex size in subjects at-risk for Alzheimer's disease : a controlled MRI study /." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487848078449575.

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25

Zastrow, Stefan, Anh Phuong, Immanuel von Bar, Vladimir Novotny, Oliver W. Hakenberg, and Manfred P. Wirth. "Primary Tumor Size in Renal Cell Cancer in Relation to the Occurrence of Synchronous Metastatic Disease." Karger, 2014. https://tud.qucosa.de/id/qucosa%3A70551.

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Objectives: To investigate the controversially discussed relationship between tumor size and the occurrence of primary synchronous metastatic disease in renal cell cancer (RCC). Patients and Methods: A consecutive RCC cohort of 2,058 patients (150 primary metastatic) who underwent surgery between 1995 and 2010 was investigated. Rates of synchronous metastases were calculated for stratified groups of tumor size. Uni- and multivariate logistic regression models were calculated for the correlation of tumor size with primary metastatic disease. Results: The rate of metastatic disease increased wi

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26

Han, Yi. "Identification of the SV40 large T antigen integration site in TRAMP mice /." Free to MU Campus, others may purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p1422928.

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27

Borde, Hema Ann. "Development of a plasmid reporter system to identify group B meningococcal genes specifically expressed in vivo utilising Cre/loxP site-specific recombination." Thesis, University of Surrey, 2001. http://epubs.surrey.ac.uk/843998/.

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Attempts to produce an effective vaccine against group B meningococcal disease have been unsuccessful due to poor immunogenicity of the capsular polysaccharide, and high variability in the currently identified outer membrane proteins. There is therefore a need to find other vaccine candidates. It is clear from studies of bacteria such as Salmonella typhimurium, that successful pathogens have the ability to specifically express genes in response to an in vivo environment. Many of these in vivo-expressed gene products will contribute to virulence of the organism and may therefore be target antig

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28

Soares, Silvia. "Fish farm health evaluation : interpretation of site mortality records." Thesis, University of Stirling, 2012. http://hdl.handle.net/1893/9268.

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In aquaculture worldwide, diseases are a significant constraint to economic expansion. The Scottish salmonid industry has experienced many cycles of development, with episodes of little or negative profitability caused by excess of production, and times of crisis due to different disease problems. In Scotland, the early implementation of regulation largely contributed to the control of infectious disease outbreaks. The recent Chilean outbreak of infectious salmon anaemia (ISA) illustrated the threats and the impacts of disease in the aquaculture industry and the importance of implementing good

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29

Demaree, Nancy. "Place, Disease and Mortality: Trimble County, Kentucky 1849-1894." TopSCHOLAR®, 2000. http://digitalcommons.wku.edu/theses/716.

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This researcher describes the characteristics of place...physical, cultural and human...of a small Kentucky county and looks at the incidence of disease and dying that occurred in that place in the last half of the nineteenth century. The impact of death on particular subsets of the general population was given a closer evaluation. Very young, females and the slave/Black communities were investigated individually. The overall site and situation of all aspects of Trimble County, Kentucky were viewed in an effort to support the notion that it is the manner in which man interacts with this enviro

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30

Boyers, Albert S. "SPECT myocardial perfusion scans : a left ventricular defect size estimation algorithm and a three dimensional computer simulation." Diss., Georgia Institute of Technology, 1991. http://hdl.handle.net/1853/14879.

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31

Zheng, Henry Public Health &amp Community Medicine Faculty of Medicine UNSW. "Walking interventions to prevent coronary heart disease in Australia - quantifying effect size, dose-response and cost reductions." Awarded by:University of New South Wales. Public Health & Community Medicine, 2009. http://handle.unsw.edu.au/1959.4/44750.

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Coronary heart disease (CHD) is the single largest cause of death in Australia. Lack of physical activity is a primary risk factor for CHD. The thesis aimed to quantify the efficacy of walking in reducing CHD risk. Meta-analyses were performed for the quantification with the application of random-effect meta-regression models. The thesis also aimed to quantify reductions in CHD-related direct healthcare costs, productivity loss and disease burden resulting from walking interventions in Australia, using the population attributable fraction model, the work and leisure models, and the consumer

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32

Cirnaru, M. D. "IMPACT OF LRRK2 KINASE ACTIVITY AT THE PRE-SYNAPTIC SITE: EARLY AND LATE EFFECTS ON PARKINSON'S DISEASE." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/353078.

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Parkinson’s disease (PD) is a common neurodegenerative disease clinically characterized by bradykinesia, rigidity and resting tremor. PD is characterized pathologically by the degeneration of nigrostriatal dopaminergic neurons and the presence of Lewy bodies containing a small protein, alpha-synuclein. Mutations in Leucine-rich repeat kinase 2 gene (LRRK2) are associated with familial and sporadic Parkinson’s disease (PD). LRRK2 is a complex protein that consists of multiple domains executing several functions, including GTP hydrolysis, kinase activity, and protein binding. There are many sing

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33

Romo, Lindsay S. "Alterations in mRNA 3′UTR Isoform Abundance Accompany Gene Expression Changes in Huntington's Disease." eScholarship@UMMS, 2017. http://escholarship.umassmed.edu/gsbs_diss/916.

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Huntington’s disease is a neurodegenerative disorder caused by expansion of the CAG repeat in huntingtin exon 1. Early studies demonstrated the huntingtin gene is transcribed into two 3′UTR isoforms in normal human tissue. Decades later, researchers identified a truncated huntingtin mRNA isoform in disease but not control human brain. We speculated the amount of huntingtin 3′UTR isoforms might also vary between control and Huntington’s disease brains. We provide evidence that the abundance of huntingtin 3′UTR isoforms, including a novel mid-3′UTR isoform, differs between patient and control ne

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34

Crino, Michelle Anne. "Food environment interventions to address obesity and related non-communicable diseases in Australia." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/18511.

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In less than 30 years the prevalence of overweight and obesity has nearly doubled worldwide. Unhealthy food environments encourage unhealthy diets and energy overconsumption, which is a prevailing driver of unhealthy weight gain, and are seen as an important contributor to the obesity epidemic. This thesis aimed to identify potential public health actions to improve the nutritional composition of the Australian packaged food environment in an effort to address obesity and related non-communicable diseases (NCDs). The research comprises of three components: (i) a review of the existing eviden

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35

Moore, Brad E., and L. Lee Glenn. "Importance of Effect Size, Control Groups, and Frequency of Use in Preventing Sexually-Transmitted Diseases." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/7495.

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36

Fedele, Stefania. "Repetitive elements in the mouse brain: expression and regulation." Doctoral thesis, SISSA, 2012. http://hdl.handle.net/20.500.11767/4715.

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Retrotransposons are expressed in a cell type-specific manner contributing to cellular differentiation and physiological activities. In brain they are expressed as independent transcriptional units or embedded in transcripts regulating RNA splicing, dendritic localization and translation. They can also mobilize to a different genomic position changing the DNA landscape of neurons. The contribution of repetitive elements to the structure of the transcriptome of an adult neuron is still unclear. To this purpose, I have analyzed the expression and regulation of the two families of retrotransposon

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37

Gyenes, Gábor. "Cardiac side-effects of adjuvant radiotherapy for early breast cancer /." [Budapest] ; Stockholm, 1997. http://diss.kib.ki.se/1997/963-9106-04-6.

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38

Cnossen, Claire. "Changes in the size distribution of granules in the gonadotropes of rats with long-term polycystic ovarian disease." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=61881.

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39

Aburad, Luiz Gustavo. "Efeitos de uma nova intervenção interdisciplinar baseada na abordagem \"Health at Every Size®\" sobre o perfil lipídico em mulheres obesas." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/6/6138/tde-14022019-111743/.

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Introdução: A obesidade é um problema de saúde pública, de etiologia multifatorial, relacionada à incidência de comorbidades, como as doenças cardiovasculares - causa número um de mortes, globalmente. Contudo, os tratamentos para reverter essa condição não surtem efeito em longo prazo, fazendo com que novas intervenções para seu tratamento sejam utilizadas, como a abordagem Health at Every Size® (HAES®), que ainda mostra resultados inconclusivos quanto à melhora no perfil lipídico relacionado às doenças cardiovasculares. Objetivo: Analisar os efeitos de uma nova intervenção interdisciplinar ba

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Seifferth, Todd A. "In-vivo strain measurement in the vicinity of an end-to-side anastomosis in the canine femoral artery." Thesis, Georgia Institute of Technology, 1990. http://hdl.handle.net/1853/18977.

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Khalife, Natasha, Vivette Glover, Anna-Liisa Hartikainen, et al. "Placental Size Is Associated with Mental Health in Children and Adolescents." Mittuniversitetet, Institutionen för samhällsvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-17060.

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Background: The role of the placenta in fetal programming has been recognized as a highly significant, yet often neglected area of study. We investigated placental size in relation to psychopathology, in particular attention deficit hyperactivity disorder (ADHD) symptoms, in children at 8 years of age, and later as adolescents at 16 years. Methodology/Principal Findings: Prospective data were obtained from The Northern Finland Birth Cohort (NFBC) 1986. Placental weight, surface area and birth weight were measured according to standard procedures, within 30 minutes after birth. ADHD symptoms, p

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Prinz, Stephanie Jeanette [Verfasser]. "Analysis of Genotype-Phenotype Relationships based on Drug Side Effects, Disease Symptoms and Mouse Phenotypic Traits / Stephanie Jeanette Prinz." München : Verlag Dr. Hut, 2016. http://d-nb.info/1106593456/34.

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Loureiro, Liliana Raquel Rodrigues. "DJ-1 mutants binding partners: insights into Parkinson's Disease." Master's thesis, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/12583.

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Mestrado em Biotecnologia - Biotecnologia Molecular<br>Parkinson´s disease (PD), the second most common progressive neurodegenerative disorder, is a multifactorial disease caused by both genetic and environmental factors. Among the genes associated with PD, DJ-1 is a multifunctional protein involved in oxidative stress response and neuroprotection. DJ-1 mutations, such as L166P, M26I and E163K lead to loss of protein function causing early onset autosomal recessive PD. Moreover, the residue C106 is considered crucial in DJ-1 function as a sensor of oxidative stress. In this study, one missense

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Gudmundsson, Anders. "Studies on particle size-selective sampling of aerosols relevant for deposition in the human airways and onto the eyes." Lund : Dept. of Industrial Engineering, Division of Working Environment, Lund Institute of Technology, Lund University, 1995. http://books.google.com/books?id=XWZtAAAAMAAJ.

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45

Kativhu, Chido L. "PhoP-regulated genes contribute to Mycobacteria tuberculosis-induced burst size necrosis in macrophages." eScholarship@UMMS, 2021. https://escholarship.umassmed.edu/gsbs_diss/1120.

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Tuberculosis (TB) is primarily a pulmonary disease caused by Mycobacterium tuberculosis (Mtb). Mtb is highly infectious, but studies have shown that only 5–15% of Mtb-infected individuals develop TB disease. The Bacille Calmette-Gu.rin (BCG) vaccine is the only commercially available Mtb vaccine, but its efficacy varies based on the strain used. The Mtb PhoPR-mutant variant, MTBVAC, has been tested as a possible attenuated live vaccine against Mtb. Although it has successfully conferred durable CD4+ T-cell responses in infants, it has also resulted in adverse effects. Our goal is to identify P

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46

Carvalho, Gomes Paula Alexandra de. "Surface plasmon resonance as a tool in the functional analysis of an immunodominant site in foot-and-mouth disease virus." Doctoral thesis, Universitat de Barcelona, 2000. http://hdl.handle.net/10803/2793.

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A fast and direct surface plasmon resonance (SPR) method for the kinetic analysis of the interactions between peptide antigens and immobilised monoclonal antibodies (mAb) has been established. Protocols have been developed to overcome the problems posed by the small size of the analytes (< 1600 Da). The interactions were well described by a simple 1:1 bimolecular interaction and the rate constants were self-consistent and reproducible. The key features for the accuracy of the kinetic constants measured were high buffer flow rates, medium antibody surface densities and high peptide concentratio

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Rurak, Brittany K. "Decline in motor control in aging and Parkinson’s disease: The role of cortico-cortical connectivity measured using dual-site TMS." Thesis, Rurak, Brittany K. (2021) Decline in motor control in aging and Parkinson’s disease: The role of cortico-cortical connectivity measured using dual-site TMS. PhD thesis, Murdoch University, 2021. https://researchrepository.murdoch.edu.au/id/eprint/64831/.

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Parkinson’s disease (PD) is a chronic, progressive, and disabling neurological condition characterised by motor- and non-motor symptoms. A debilitating motor symptom of PD is resting tremor, which is the involuntary shaking of one or multiple body parts that substantially affects activities of daily living and functional independence. As PD resting tremor is not associated with the typical progressive degeneration of dopaminergic neurons in the basal ganglia, other brain regions likely play a role in tremor production. The overarching aim of this thesis was to use dual-site transcranial magnet

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Gomes, Paula Alexandra de Carvalho. "Surface plasmon resonance as a tool in the functional analisys of an immunodominant site in foot-and-mouth disease virus." Phd thesis, Instituições estrangeiras -- -University of Barcelona -- -Department of Organic Chemistry, 2000. http://dited.bn.pt:80/30419.

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A fast and direct surface plasmon resonance (SPR) method for the kinetic analysis of the interactions between peptide antigens and immobilised monoclonal antibodies (mAb) has been established. Protocols have been developed to overcome the problems posed by the small size of the analytes (< 1600 Da). The interactions were well described by a simple 1:1 bimolecular interaction and the rate constants were self-consistent and reproducible. The key features for the accuracy of the kinetic constants measured were high buffer flow rates, medium antibody surface densities and high peptide concentratio

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49

Mensah, Eric. "Creation of a Site-Directed Mutant of Hen Egg White Lysozyme Working Toward Site-Specific Oxidation as it Relates to Protein Structure." Connect to resource online, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1251756763.

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Passare, Galina. "Drug use and side effects in the elderly : findings from the Kungsholmen Project /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-365-5/.

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